Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:2814360 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
281436028183824023hypothetical proteinBLASTP
28186572819433777hypothetical proteinBLASTP
281948228205581077integral membrane proteinQuickGO ontology
282060828227312124hypothetical proteinBLASTP
282365628252121557integraseQuickGO ontologyBLASTP
28253482826283936secreted proteinQuickGO ontology
28264472827148702hypothetical proteinBLASTP
282739628293811986hypothetical proteinBLASTP
282946028306561197Sfr proteinQuickGO ontologyBLASTP
283065328329622310penicillin binding proteinQuickGO ontologyBLASTP
28330152833686672rod shape-determining proteinQuickGO ontologyBLASTP
283370028347251026rod shape-determining proteinQuickGO ontologyBLASTP
283490828359391032rod shape-determining proteinQuickGO ontologyBLASTP
28362472836660414nucleoside diphosphate kinaseQuickGO ontologyBLASTP
28367852837141357hypothetical proteinBLASTP
283714828384821335folylpolyglutamate synthaseQuickGO ontologyBLASTP
283895728415812625valyl-tRNA synthetaseQuickGO ontologyBLASTP
284171928427261008hypothetical proteinBLASTP
284279828440841287ATP-dependent protease ATP-binding subunitQuickGO ontologyBLASTP
28442762844986711ATP-dependent Clp protease proteolytic subunitQuickGO ontologyBLASTP
28450372845696660ATP dependent Clp protease proteolytic subunit 1QuickGO ontologyBLASTP
284600028474061407trigger factorQuickGO ontologyBLASTP
2847576284765277tRNA-ProQuickGO ontology
28479832848177195hypothetical proteinBLASTP
284881228499811170integral membrane proteinQuickGO ontologyBLASTP
28499922850486495hypothetical proteinBLASTP
285051028516971188integral membrane proteinQuickGO ontologyBLASTP
285191128531521242hypothetical proteinBLASTP
28531632854005843DNA repair hydrolase fragmentQuickGO ontologyBLASTP
28541122854591480ribose-5-phosphate isomerase BQuickGO ontologyBLASTP
285480628560741269amino acid permeaseQuickGO ontologyBLASTP
28561042856250147hypothetical protein
28563292857072744biotin synthaseQuickGO ontologyBLASTP
285730028586851386amino acid permeaseQuickGO ontologyBLASTP