Pre_GI Gene

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Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:883500 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
883572883937366hypothetical protein
884059884292234hypothetical protein
884559885191633hypothetical protein
8855918870361446proteaseQuickGO ontologyBLASTP
887118887300183hypothetical protein
887475887681207transcriptional regulatorQuickGO ontologyBLASTP
8876988884927952-haloalkanoic acid dehalogenaseQuickGO ontologyBLASTP
888636888812177hypothetical protein
888992889162171hypothetical protein
889498889851354hypothetical proteinBLASTP
890067890906840RNA polymerase sigma factorQuickGO ontologyBLASTP
891284892279996AraC-family transcriptional regulatorQuickGO ontologyBLASTP
892951893352402peptidase inhibitorQuickGO ontology
893346893903558IS630 family transposaseQuickGO ontologyBLASTP
893900894439540IS630 family transposaseQuickGO ontologyBLASTP
894729895703975hypothetical protein
8961508972831134hypothetical proteinBLASTP
8976438990041362hypothetical proteinBLASTP
899196899828633methyltransferaseQuickGO ontologyBLASTP
900012900425414TetR-family transcriptional regulatorQuickGO ontologyBLASTP
9015049025921089hypothetical proteinBLASTP