Pre_GI Gene

Some Help

Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:6444500 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
644451864464641947D-ribose ABC transporter permease proteinQuickGO ontologyBLASTP
644645464480221569D-ribose ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
644801964490831065LacI-family transcriptional regulator ribose operon repressorQuickGO ontologyBLASTP
64494416449773333hypothetical proteinBLASTP
64498716450188318hypothetical proteinBLASTP
64502296450627399hypothetical proteinBLASTP
645062464533262703hypothetical proteinBLASTP
645332364543301008hypothetical proteinBLASTP
64545626454924363hypothetical proteinBLASTP
64549036455595693hypothetical proteinBLASTP
64557286456090363hypothetical proteinBLASTP
645616064584362277exodeoxyribonuclease VQuickGO ontologyBLASTP
645867964599681290citrate synthaseQuickGO ontologyBLASTP
646062564628772253cation-transporting P-type ATPaseQuickGO ontologyBLASTP
64629836463222240copper chaperoneQuickGO ontologyBLASTP
64635336464231699TetR-family transcriptional regulatorQuickGO ontologyBLASTP
646439964667172319hypothetical proteinBLASTP