Pre_GI Gene

Some Help

Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:5616000 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
561603256184072376hypothetical proteinBLASTP
561872556199961272hypothetical proteinBLASTP
56199865620975990carbon monoxide dehydrogenase accessory proteinQuickGO ontologyBLASTP
56210685621892825hypothetical proteinBLASTP
56222865623119834morphological differentiation-associated proteinQuickGO ontologyBLASTP
562369956247931095septum site determining proteinQuickGO ontologyBLASTP
562479056260911302hypothetical proteinBLASTP
56263725627001630hypothetical proteinBLASTP
56269985627498501hypothetical protein
56274825627787306hypothetical proteinBLASTP
56279075628140234hypothetical protein
56281275628567441hypothetical proteinBLASTP
56283155629013699hypothetical protein
562901056315172508ATP-dependent RNA helicaseQuickGO ontologyBLASTP
56315985631939342anti-sigma factor antagonistQuickGO ontologyBLASTP
56320695632509441anti-sigma factorQuickGO ontologyBLASTP
563282456352292406inorganic proton pyrophosphataseQuickGO ontologyBLASTP
56354465636042597hypothetical proteinBLASTP
563615856377471590rRNA or tRNA methyltransferaseQuickGO ontologyBLASTP
563793856401662229serinethreonine protein kinaseQuickGO ontologyBLASTP
56401635640504342hypothetical protein