Pre_GI Gene

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Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:5253923 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5253923525415923730S ribosomal protein S18QuickGO ontologyBLASTP
52542175254825609single-strand DNA-binding proteinQuickGO ontologyBLASTP
5254905525519529130S ribosomal protein S6QuickGO ontologyBLASTP
52555175255831315hypothetical proteinBLASTP
525605452571751122hypothetical proteinBLASTP
525727452583051032hypothetical proteinBLASTP
525838952599061518transmembrane proteinQuickGO ontologyBLASTP
526001652628052790penicillin-binding proteinQuickGO ontologyBLASTP
52630845263767684transcriptional regulator PadR-like familyQuickGO ontologyBLASTP
5263812526489410831L-myo-inositol-1-phosphate synthaseQuickGO ontologyBLASTP
526497252662341263hypothetical proteinBLASTP
52663495266840492hypothetical proteinBLASTP
526695952684011443RNA nucleotidyltransferaseQuickGO ontologyBLASTP
526864852710652418hypothetical proteinBLASTP
527111252733792268transmembrane proteinQuickGO ontologyBLASTP
527349852752191722hypothetical proteinBLASTP
52752495275962714RNA polymerase sigma-70 factorQuickGO ontologyBLASTP
52759595276882924hypothetical proteinBLASTP