Pre_GI Gene

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Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:5005913 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
50059135006737825hypothetical proteinBLASTP
50067505007181432regulatory proteinQuickGO ontologyBLASTP
50073675008239873DNA-binding proteinQuickGO ontologyBLASTP
50082365008451216hypothetical protein
50084445008689246hypothetical protein
50087115009085375hypothetical proteinBLASTP
50093945009873480hypothetical protein
50099035010520618hypothetical proteinBLASTP
50105215011432912hypothetical proteinBLASTP
501167050139942325hypothetical proteinBLASTP
50139915014383393hypothetical proteinBLASTP
50144245014741318hypothetical proteinBLASTP
50147925015124333hypothetical proteinBLASTP
50158835016191309integral membrane proteinQuickGO ontologyBLASTP
50164025017253852integral membrane proteinQuickGO ontologyBLASTP
501724350185771335integral membrane proteinQuickGO ontologyBLASTP
501859250201331542hypothetical proteinBLASTP
502017350216031431ATPGTP-binding proteinQuickGO ontologyBLASTP
502172350233511629hypothetical proteinBLASTP
50234295023974546acetyltransferaseQuickGO ontologyBLASTP
502410050242251265S ribosomal RNAQuickGO ontologyBLASTP