Pre_GI Gene

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Host: NC_003112 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003112:1423528 Neisseria meningitidis MC58, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
14235281424166639keto-hydroxyglutarate-aldolaseketo-deoxy- phosphogluconate aldolaseQuickGO ontologyBLASTP
142442514254651041alcohol dehydrogenase zinc-containingQuickGO ontologyBLASTP
142561914266681050AG-specific adenine glycosylaseQuickGO ontologyBLASTP
14268311427013183hypothetical proteinBLASTP
14270851427645561Cu-Zn-superoxide dismutaseQuickGO ontologyBLASTP
14282101429184975IS1106 transposaseQuickGO ontologyBLASTP
142944114316692229ABC transporter family proteinQuickGO ontologyBLASTP
14324821433021540IS1016C2 transposaseQuickGO ontologyBLASTP
14333581433792435hypothetical proteinBLASTP
14338331434024192FrpAC-related proteinQuickGO ontologyBLASTP
14340591434787729hypothetical proteinBLASTP
143480114360031203FrpAC-related proteinQuickGO ontologyBLASTP
14364341436796363hypothetical protein
14379981438492495hypothetical protein
14386201439048429FrpAC-related proteinQuickGO ontologyBLASTP
14392851439824540hypothetical proteinBLASTP
14399951440648654IS1016C2 transposaseQuickGO ontologyBLASTP
14412541442063810FrpC operon proteinQuickGO ontologyBLASTP
14428361443609774FrpC operon proteinQuickGO ontologyBLASTP
144362614491155490iron-regulated protein FrpCQuickGO ontologyBLASTP
144945714520602604aminopeptidase NQuickGO ontologyBLASTP
14521911452985795hypothetical proteinBLASTP
14537321454601870lipid A biosynthesis lauroyl acyltransferaseQuickGO ontologyBLASTP
14546521455188537Holliday junction resolvaseQuickGO ontologyBLASTP