Pre_GI Gene

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Host: NC_003103 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003103:225956 Rickettsia conorii str. Malish 7, complete genome

Host Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
225956226321366similarity to prolyl endopeptidaseQuickGO ontologyBLASTP
226648226809162similarity to prolyl endopeptidaseQuickGO ontologyBLASTP
226910227494585similarity to prolyl endopeptidaseQuickGO ontologyBLASTP
2276712288731203coproporphyrinogen III oxidaseQuickGO ontologyBLASTP
229522229716195hypothetical proteinBLASTP
229730230050321hypothetical proteinBLASTP
230244230432189hypothetical proteinBLASTP
2304832316821200protonsodium-glutamate symport proteinQuickGO ontologyBLASTP
231723232037315periplasmic divalent cation tolerance proteinQuickGO ontologyBLASTP
232040232558519hypothetical proteinBLASTP
2326262338131188dihydrolipoamide acetyltransferaseQuickGO ontologyBLASTP
23397823676427872-oxoglutarate dehydrogenase e1 component EC1242QuickGO ontologyBLASTP
2368982383881491thermostable carboxypeptidaseQuickGO ontologyBLASTP
2385652402021638DNA repair protein RecNQuickGO ontologyBLASTP
240210240965756hypothetical proteinBLASTP
241198241368171similarity to cation transport regulator ChaBQuickGO ontologyBLASTP
2415052426261122dnaJ proteinQuickGO ontologyBLASTP
2427552446381884molecular chaperone DnaKQuickGO ontologyBLASTP
2447022461951494heat shock protease EC3421-QuickGO ontologyBLASTP
247010247210201hypothetical proteinBLASTP
247351247698348hypothetical proteinBLASTP
247866248339474hypothetical proteinBLASTP