Pre_GI Gene

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Host: NC_003103 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003103:1133806 Rickettsia conorii str. Malish 7, complete genome

Host Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
11338061134285480NADH dehydrogenase subunit IQuickGO ontologyBLASTP
113447211354911020NADH dehydrogenase subunit HQuickGO ontologyBLASTP
113558011376102031NADH dehydrogenase gamma subunitQuickGO ontologyBLASTP
11375981137954357hypothetical proteinBLASTP
113812311407592637aconitate hydrataseQuickGO ontologyBLASTP
11409411141279339ATP synthase subunit epsilonQuickGO ontologyBLASTP
114133711428361500ATP synthase subunit BQuickGO ontologyBLASTP
11429311143902972ATP synthase subunit CQuickGO ontologyBLASTP
114403511456361602ATP synthase subunit AQuickGO ontologyBLASTP
11457331146287555ATP synthase subunit DQuickGO ontologyBLASTP
114644911478281380dihydrolipoamide dehydrogenaseQuickGO ontologyBLASTP
11479791148143165similarity to strees induced DNA-binding proteins the dps familyQuickGO ontologyBLASTP
11486051148910306hypothetical proteinBLASTP
11494511149744294hypothetical proteinBLASTP
11498251150127303similarity to beta-lactamaseQuickGO ontologyBLASTP
11502661150538273similarity to beta-lactamaseQuickGO ontologyBLASTP
115070011530722373penicillin-binding protein 1aQuickGO ontologyBLASTP
115307611544131338hypothetical proteinBLASTP
11548361155051216hypothetical proteinBLASTP
11554291155581153hypothetical proteinBLASTP
11560961156449354hypothetical proteinBLASTP