Pre_GI Gene

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Host: NC_002973 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002973:461712 Listeria monocytogenes str. 4b F2365, complete genome

Host Lineage: Listeria monocytogenes; Listeria; Listeriaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was isolated in 1985 in California, USA, during an outbreak of listeriosis among patients with AIDS. The strain is of serotype 4b and was isolated from a cheese product that caused the outbreak. This organism, which causes listeriosis, is one of the leading causes of death from food-borne pathogens especially in pregnant women, newborns, the elderly, and immunocompromised individuals. It is found in environments such as decaying vegetable matter, sewage, water, and soil, and it can survive extremes of both temperatures (1-45 degrees C) and salt concentration marking it as an extremely dangerous food-born pathogen, especially on food that is not reheated. This organism is enteroinvasive, and utilizes an actin-based motility system by using a surface protein, ActA, that promotes actin polymerization, to spread intercellularly using the polymerized cytoskeletal protein as a "motor". There are 13 serovars associated with Listeria monocytogenes, and the serovar 4b strains are more commonly associated with invasive disease.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4617124642942583glycosyl hydrolase family 38QuickGO ontologyBLASTP
464317465192876transcriptional regulator LysR familyQuickGO ontologyBLASTP
465310465879570acetyltransferase CysELacALpxANodL familyQuickGO ontologyBLASTP
465893466639747oxidoreductase short-chain dehydrogenasereductase familyQuickGO ontologyBLASTP
466835467260426hypothetical proteinBLASTP
4675164741036588wall-associated protein putativeQuickGO ontologyBLASTP
474103474585483hypothetical proteinBLASTP
474856474969114hypothetical proteinBLASTP
475465475815351hypothetical proteinBLASTP
475978476568591hypothetical proteinBLASTP
476595477041447hypothetical proteinBLASTP
477058477666609hypothetical proteinBLASTP
477810478076267hypothetical proteinBLASTP
478116478472357hypothetical protein
478648478902255hypothetical protein
478915479082168hypothetical protein
479199479693495hypothetical protein
479903480169267hypothetical proteinBLASTP
480288481076789hypothetical protein
481229481894666hypothetical proteinBLASTP
482137482376240hypothetical protein
482394482981588hypothetical proteinBLASTP
483006483152147hypothetical proteinBLASTP
483130483705576PBS lyase HEAT-like repeat domain proteinQuickGO ontologyBLASTP