Pre_GI Gene

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Host: NC_002950 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002950:879930 Porphyromonas gingivalis W83, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
879930880292363lipoprotein putativeQuickGO ontologyBLASTP
880418880825408hypothetical proteinBLASTP
880958881272315hypothetical proteinBLASTP
881310881990681hypothetical proteinBLASTP
8821538832381086ISPg1 transposaseQuickGO ontologyBLASTP
883361884209849transcriptional regulator AraC familyQuickGO ontologyBLASTP
8843068856641359MATE efflux family proteinQuickGO ontologyBLASTP
886360886836477hypothetical proteinBLASTP
887543887971429hypothetical proteinBLASTP
8887708897981029hypothetical proteinBLASTP
8897988916631866hypothetical proteinBLASTP
8920888933501263hypothetical proteinBLASTP
893720893857138hypothetical protein
8956178969151299integraseQuickGO ontologyBLASTP
8973538985341182hypothetical proteinBLASTP
8985129025434032hypothetical proteinBLASTP
902871903764894mobilizable transposon excision protein putativeQuickGO ontologyBLASTP
9039009049641065mobilizable transposon hypothetical protein putativeQuickGO ontologyBLASTP
904961905272312hypothetical proteinBLASTP
90542990552193hypothetical protein
90556490565188tRNA-SerQuickGO ontology
9078949094741581hypothetical proteinBLASTP
909579910577999hypothetical proteinBLASTP
910562911332771hypothetical proteinBLASTP
911360911668309DNA binding protein excisionase family putativeQuickGO ontologyBLASTP
9116569128221167hypothetical proteinBLASTP