Pre_GI Gene

Some Help

Host: NC_002950 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002950:353549 Porphyromonas gingivalis W83, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3535493546371089hypothetical proteinBLASTP
3547883558191032arginineornithine transport system ATPaseQuickGO ontologyBLASTP
3558483570261179serinethreonine transporterQuickGO ontologyBLASTP
357149357478330hypothetical proteinBLASTP
3576793591721494histidine ammonia-lyaseQuickGO ontologyBLASTP
359175359804630hypothetical proteinBLASTP
3598293610641236hypothetical proteinBLASTP
3609973621511155hypothetical proteinBLASTP
3622453635161272imidazolonepropionaseQuickGO ontologyBLASTP
363617364519903formiminotransferase-cyclodeaminase-related proteinQuickGO ontologyBLASTP
364568365083516DNA-binding protein histone-like familyQuickGO ontologyBLASTP
3657593677351977transcription termination factor RhoQuickGO ontologyBLASTP
367963368871909hypothetical proteinBLASTP
368882369841960glycosyl transferase group 2 family proteinQuickGO ontologyBLASTP
369894370796903tRNA delta2-isopentenylpyrophosphate transferaseQuickGO ontologyBLASTP
370813371382570hypothetical proteinBLASTP
371467371619153hypothetical proteinBLASTP
3716703751973528hypothetical proteinBLASTP
375202375747546hypothetical proteinBLASTP
376206376496291hypothetical protein
3772713784521182methionine gamma-lyaseQuickGO ontologyBLASTP