Pre_GI Gene

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Host: NC_002950 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002950:2068500 Porphyromonas gingivalis W83, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
20693052069595291CRISPR-associated protein Cas2QuickGO ontologyBLASTP
206961520727103096CRISPR-associated protein Cas1QuickGO ontologyBLASTP
20727712073532762CRISPR-associated TM1791 family proteinQuickGO ontologyBLASTP
20735292073972444hypothetical proteinBLASTP
20739692074670702CRISPR-associated TM1792 family proteinQuickGO ontologyBLASTP
207468420758741191CRISPR-associated TM1793 family proteinQuickGO ontologyBLASTP
207587620775221647CRISPR-associated TM1811 family proteinQuickGO ontologyBLASTP
207751520789571443hypothetical proteinBLASTP
20789732079191219hypothetical proteinBLASTP
208155020834271878glucose-inhibited division protein AQuickGO ontologyBLASTP
208346120852601800excinuclease ABC C subunitQuickGO ontologyBLASTP
20852672085719453D-tyrosyl-tRNA deacylaseQuickGO ontologyBLASTP
20857242086074351hypothetical proteinBLASTP
20860612086930870deoxyribose-phosphate aldolaseQuickGO ontologyBLASTP
20869712087132162hypothetical proteinBLASTP
20872412088119879polyprenyl synthetaseQuickGO ontologyBLASTP
20882732088911639hypothetical proteinBLASTP