Pre_GI Gene

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Host: NC_002950 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002950:1748582 Porphyromonas gingivalis W83, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
174858217496881107efflux transporter MFP component RND familyQuickGO ontologyBLASTP
174968517510521368outer membrane efflux proteinQuickGO ontologyBLASTP
175213417522411085S ribosomal RNAQuickGO ontologyBLASTP
17523881755221283423S ribosomal RNAQuickGO ontologyBLASTP
1755340175541677tRNA-AlaQuickGO ontology
1755418175549174tRNA-IleQuickGO ontologyBLASTP
17555011755656156hypothetical protein
17557851755943159hypothetical proteinBLASTP
17560561757530147516S ribosomal RNAQuickGO ontologyBLASTP
17575301757748219hypothetical proteinBLASTP
17577771757944168hypothetical proteinBLASTP
175852817596851158ISPg4 transposaseQuickGO ontologyBLASTP
1760322176042099hypothetical protein
176057917621861608phosphoenolpyruvate carboxykinaseQuickGO ontologyBLASTP
176248217637381257phosphoglycerate kinaseQuickGO ontologyBLASTP
17638451763952108hypothetical protein
176393617653301395hypothetical proteinBLASTP
176655217685281977glycogen debranching enzyme archaeal type putativeQuickGO ontologyBLASTP
176852517697871263glycosyl transferase group 1 family proteinQuickGO ontologyBLASTP
176978417710701287hypothetical proteinBLASTP
17710671771543477hypothetical protein