Pre_GI Gene

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Host: NC_002950 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002950:1511955 Porphyromonas gingivalis W83, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
151195515144862532thiol proteasehemagglutinin PrtT precursor putativeQuickGO ontologyBLASTP
15146271515112486riboflavin synthase subunit betaQuickGO ontologyBLASTP
15150931515203111hypothetical protein
15152041515890687TPR domain proteinQuickGO ontologyBLASTP
15160761516759684DNA-binding response regulator LuxR familyQuickGO ontologyBLASTP
151682415186891866sensor histidine kinaseQuickGO ontologyBLASTP
15189711519186216hydrolaseQuickGO ontologyBLASTP
151916215198306692-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseQuickGO ontologyBLASTP
1520059152013577tRNA-AspQuickGO ontologyBLASTP
152044315216691227integraseQuickGO ontologyBLASTP
152179615238142019ATPase putativeQuickGO ontologyBLASTP
152467515267502076hypothetical protein
15267401527357618hypothetical protein
15274481527615168lysozyme-related proteinQuickGO ontologyBLASTP
15276921528120429hypothetical proteinBLASTP
15288861529302417hypothetical proteinBLASTP
15293861529712327BLASTP
152999815313171320MATE efflux family proteinQuickGO ontologyBLASTP
15314531532301849transcriptional regulator AraC familyQuickGO ontologyBLASTP
153242415335091086ISPg1 transposaseQuickGO ontologyBLASTP
15336721534352681hypothetical proteinBLASTP
15343901534704315hypothetical proteinBLASTP
15348371535244408hypothetical proteinBLASTP
15353701535732363lipoprotein putativeQuickGO ontologyBLASTP
153573915369411203integraseQuickGO ontologyBLASTP
153696715381961230integraseQuickGO ontologyBLASTP
15384881538688201BLASTP
15387901539257468hypothetical proteinBLASTP
15392841539742459hypothetical proteinBLASTP
15397221539859138hypothetical proteinBLASTP
15401001540459360hypothetical proteinBLASTP
15404661540987522hypothetical proteinBLASTP
15410001541227228hypothetical proteinBLASTP
15412501541531282hypothetical proteinBLASTP
15421221542766645hypothetical proteinBLASTP
15427631543335573hypothetical proteinBLASTP
15433501543961612methlytransferase UbiECOQ5 familyQuickGO ontologyBLASTP
154508015480883009type I restriction-modification system M subunit putativeQuickGO ontologyBLASTP
15482611548491231hypothetical proteinBLASTP
15486711549138468hypothetical proteinBLASTP
15491731549820648hypothetical proteinBLASTP
15498511550315465conjugative transposon protein TraQQuickGO ontologyBLASTP
15503281550906579conjugative transposon protein TraOQuickGO ontologyBLASTP
155090015519251026conjugative transposon protein TraNQuickGO ontologyBLASTP
155194815533091362conjugative transposon protein TraMQuickGO ontologyBLASTP
15532991553586288hypothetical proteinBLASTP
15535831554206624conjugative transposon protein TraKQuickGO ontologyBLASTP
155421815553241107conjugative transposon protein TraJQuickGO ontologyBLASTP
15553561555985630conjugative transposon protein TraIQuickGO ontologyBLASTP
155601215585372526conjugative transposon protein TraGQuickGO ontologyBLASTP
15585341558869336conjugative transposon protein TraFQuickGO ontologyBLASTP
15588731559175303conjugative transposon protein TraEQuickGO ontologyBLASTP
15593651560069705hypothetical proteinBLASTP
15600741560460387conjugative transposon protein TraCQuickGO ontologyBLASTP
15604471561256810conjugative transposon protein TraAQuickGO ontologyBLASTP