Pre_GI Gene

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Host: NC_002950 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002950:1334500 Porphyromonas gingivalis W83, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1334551133464393hypothetical protein
13346741334952279DNA-binding protein HUQuickGO ontologyBLASTP
13350641335555492anaerobic ribonucleoside-triphosphate reductase activating proteinQuickGO ontologyBLASTP
133558813379842397anaerobic ribonucleoside triphosphate reductaseQuickGO ontologyBLASTP
133851113396681158ISPg4 transposaseQuickGO ontologyBLASTP
13398221340724903ISPg3 transposaseQuickGO ontologyBLASTP
134146313415701085S ribosomal RNAQuickGO ontologyBLASTP
13417171344550283423S ribosomal RNAQuickGO ontologyBLASTP
1344669134474577tRNA-AlaQuickGO ontology
1344747134482074tRNA-IleQuickGO ontologyBLASTP
13448301344985156hypothetical protein
13451141345272159hypothetical proteinBLASTP
13453851346859147516S ribosomal RNAQuickGO ontologyBLASTP
13468591347077219hypothetical proteinBLASTP
13471061347273168hypothetical proteinBLASTP
1347511134760999hypothetical protein
134766013492911632delta-1-pyrroline-5-carboxylate dehydrogenaseQuickGO ontologyBLASTP
13493681350297930hypothetical proteinBLASTP
135030413515331230acetylornithine aminotransferase putativeQuickGO ontologyBLASTP
13517721351927156hypothetical proteinBLASTP
13519831352549567elongation factor PQuickGO ontologyBLASTP
13530851353591507DNA-binding protein histone-like familyQuickGO ontologyBLASTP
135389413551591266UDP-glucose-6 dehydrogenase putativeQuickGO ontologyBLASTP
135549213565741083phosphoserine aminotransferaseQuickGO ontologyBLASTP