Pre_GI Gene

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Host: NC_002950 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002950:115917 Porphyromonas gingivalis W83, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
11583511593399hypothetical protein
1159171183762460phenylalanyl-tRNA synthetase beta subunitQuickGO ontologyBLASTP
119142119309168hypothetical proteinBLASTP
119338119556219hypothetical proteinBLASTP
119556121030147516S ribosomal RNAQuickGO ontologyBLASTP
121143121301159hypothetical proteinBLASTP
121430121585156hypothetical protein
12159512166874tRNA-IleQuickGO ontologyBLASTP
12167012174677tRNA-AlaQuickGO ontology
121865124698283423S ribosomal RNAQuickGO ontologyBLASTP
1248451249521085S ribosomal RNAQuickGO ontologyBLASTP
1254811275082028DNA topoisomerase IIIQuickGO ontologyBLASTP
1288581299941137glycosyl transferase group 4 family proteinQuickGO ontologyBLASTP
1302411314491209UDP-N-acetyl-D-mannosaminuronic acid dehydrogenaseQuickGO ontologyBLASTP
1314711326941224hypothetical protein
1327311337711041glycosyl transferase group 1 family proteinQuickGO ontologyBLASTP
1338201350881269capsular polysacharride biosynthesis gene putativeQuickGO ontologyBLASTP