LOCUS NC_017276:8 18410 bp DNA linear BCT 09-SEP-2013 DEFINITION Sulfolobus islandicus REY15A chromosome, complete genome. ACCESSION NC_017276 SOURCE Sulfolobus islandicus REY15A chromosome, complete genome. COMMENT locus start: 774690; locus end: 793099 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.684303; n0_4mer:D = 18.655764; n0_4mer:PS = 31.824826 FEATURES Location/Qualifiers source 1..18410 /organism="Sulfolobus islandicus REY15A chromosome, complete genome." gene -885..8 /gene="" /locus_tag="" /db_xref="773804..774697" CDS -885..8 /gene="" /product="ABC transporter" /translation="MIVVSSIVKKYGNKIALDNVSLEVKKGEFVSLIGPNGAGKTTLI RILLTLMKPDKGEVQILGENPFRNKRIFKAIGYVQEIPNYPPFLTGRQVLELSAKIRG VDKSEVKRVLEFVEMENYANNPIIKYSKGMVQRIAIAESLLGNPSILIMDEPNMGIDP IFSLKTRELLNKLKRKDNVSILMTSHELEDVKKLSDRIFMIYKGKIVFSGTVEDMIKE FLGIQVIVETDEIENAEEALKGIEYVKGVFNDGNRLIVKLNEDRREDLLRDLVTSGVK VKGFYIDLNLEEAYMRALRNV" gene 1..834 /gene="" /locus_tag="" /db_xref="774690..775523" CDS 1..834 /gene="" /product="putative ABC-2 type transport permease" /translation="MFEIMLYEWRRAIARKKVIVLSIITFIFELGTYLAIYLAPSHSL KTLIIPLSPYLWALGVLLPQVLLIHFLAISIASGSMAEEYEQGTVDYFISKPITRLRF IMEKWLGSFSLLLIIYLFMVVLALILSSLLFGVQSELIVLPELFFSIIFSTLVFLNIA FAIGEILRRSNLSFTISGFILIASIIVSDVLIFVSVITHNSNYETISEYLPTWGSTEL PFMLLQNSPLSAIARGLNILPSISNNVSLAIVSIVVYSLLPLVLSIINFLGRDISKKV S" gene 970..1458 /gene="" /locus_tag="" /db_xref="775659..776147" gene 1513..1866 /gene="" /locus_tag="" /db_xref="776202..776555" CDS 1513..1866 /gene="" /product="" /translation="MHVNIGFSSIYVILAVNAWTGEVVVSLVRRPNSESVKYFLRYFK RRFGSGRVYMVMDNYSPHKTKGTLEVCRRKGIHPIFTPPYSPELNMAEAVFKSLKEYM SNKIFYTIEDVKKLY" gene 1965..2720 /gene="" /locus_tag="" /db_xref="776654..777409" CDS 1965..2720 /gene="" /product="hypothetical protein" /translation="VLIYPEHRYIDLDRNGKQKSGIIPPNVVVGNAFNSFSFFLEAPR PISWEDGRDLEKVWKFYSLVRPDMLIYEGIEVDIVDFNGDIPIKRPHYIVEFKELENW WKRWRYLKDYKPLSGNEWRARWLKGLYEGLAEVLGVKEKELPSFSEGETKRLKEYKVI ELYKAIYRPKKGMVISRVSVDITVKDDLGEGIILVDDVRFDYNKLKDIVDELTNTNSV ENVDIRELAYKFALSKRDEFIAWLKSQGISLSL" gene 3088..4341 /gene="" /locus_tag="" /db_xref="777777..779030" CDS 3088..4341 /gene="" /product="hypothetical protein" /translation="MLILATLGSDKSVTTINAILTEIFTGLNPNKIIIFREDPQKKDI KGMEKALEYLGVNTLIEEKVIGEGIKLWREKIRNEEIDIFDITPGRKYMALSATYYSR AEEIRYVYLKDEREGYNIFGYVPFEQLKVINVRIGDEIPYDPPLTQNVNEAESLLDVD SLRAFINILGLHGKVEINGIDLENPDQVEEICLFRSGKYKYEEEKDIIKEAERGSLFL ADTNVYIRLGNRLRSLVYNRKYGFRLLSSKNTFNELYNHTAQDTQKIDENKVKFILGM LSYRSLHVPPITSQVRSSGDMGLINEALEIKKNVEDNVVLITADKALGLTAQSKGLRT IILSKVRKEIGEWDIGELLFCLSFYNDYRNGIRRMIEISLNGSKIAELHSYYHLQERR VKVRVVDKRYNYPKILEILSEILAT" gene 4534..5001 /gene="" /locus_tag="" /db_xref="779223..779690" CDS 4534..5001 /gene="" /product="hypothetical protein" /translation="VIVLPKGYLNLGGYTINSSDNDGVVPGEFAFSFYRSTLPDEKNV EDEIRSIVSKAANNVNVKYEMEVKSYVPGSLTPKDSKLVKVAEECVYRVINVLPETII AQIRYDGVFFRPFAEVINIGPGDNAHIPNESVSNIVKTSRIYGCIISTLFLRD" gene 5224..5433 /gene="" /locus_tag="" /db_xref="779913..780122" CDS 5224..5433 /gene="" /product="VapB-type antitoxin" /translation="MAKTITISNKAYEALLKEKKEGESFSDVIIRLTSSGNKEKLLKF AGIWKDAKIDDVMKELEEMWSKWNV" gene 5421..5813 /gene="" /locus_tag="" /db_xref="780110..780502" CDS 5421..5813 /gene="" /product="VapC-type toxin" /translation="MECLDSDIIIDFLKGRDEAVNYIKKSKEELAITSINVFEVYFGG YKIGKTKCLEDFFSSLKILTLDYNASKKAAEIGTKLSNEGRQIEVKDLLIASICIVNG CTLVTSNIKHFSRINELKLKNWRNEVFY" gene 6059..7264 /gene="" /locus_tag="" /db_xref="780748..781953" CDS 6059..7264 /gene="" /product="IS200/IS605 family OrfB protein" /translation="MSDVGLRFRAYADEQTLRALKAQLRLACEVYNTLRWADIYFHER DGKGLTKTELRQLALDLRKQDKQYQHLYSQTLQQIADRFYDARQRFFEGLAHFPKEKK AHKWYSLVYPQSGWKVMKVREIRTKSKKNKKKVMTLQLSNLGIFNVVVHRDFQLEKVE RVVVKLAPSGRLYITFVVDQEYPQLPKTNKVVAVDVGVEKLLTTSDGEYVPNMRPYEK ALNKMKRLHKALSRKKFLSHNWFKAKVKLARAYEHLKNLRMDMYMKLGKYFAEHYDVL VMEDIHVKQIVGKSLRRLRMRLHDVAFHEFRSIMEYQVGKYGKEIRFVNPAFTSMICA RCGYVKKDLALADRVFVCPSCGWTVDRDYNASLNILSRSGLERPLVPVELRPLPLASL GCEAGSHVR" gene 7716..8684 /gene="" /locus_tag="" /db_xref="782405..783373" CDS 7716..8684 /gene="" /product="CRISPR-associated protein" /translation="MNKVHVSAVGTSLLKNSLSADNVKKEVEDLGLKDWDRLKFDDDR QNKIRDNFTTLKDLLLNFLKSKGKEASAELDSLLSAIEKLQHKKEELYVFLYTTNTWN SKLAGEVIKNYLEEEGIKSELATVKSISSEETFHEGIEDLFDKVIYKILKFKEEGKEV YINATAGLKPETTFLTLAGLLAGADLVYYKYQEFNDVVFLPSPPITISPRYLEWLIEF ANYGYTLSEKKAEELGIPVRLLEVRNLVERKGEDAYRLKDWVRKMLGIYLPAGVTSMY YKVIVEGEEEKVFDNETEAYNYMEKKRKEGKRVRVEVPNKVYFLGL" gene 8647..8991 /gene="" /locus_tag="" /db_xref="783336..783680" CDS 8647..8991 /gene="" /product="hypothetical protein" /translation="LKFQIRCISLDFELEIEGVKIKAKIDTGFDGEIIVNKEVFDKIP YDPSQGPRICTASMECYSTYVKLAKIKYLGKEVISTVLNSPVIEKNIVGEGLLRKVGA IINYKDNTIEDI" gene 9155..9406 /gene="" /locus_tag="" /db_xref="783844..784095" CDS 9155..9406 /gene="" /product="hypothetical protein" /translation="MINKITIRNFKSLESVDVDLKKINVLIGPNGSGKTAFVESLLLS RNIISKLLGYSPFGMWWGYENVVYKRDTSRSIVIEFKIF" gene 9538..9717 /gene="" /locus_tag="" /db_xref="784227..784406" CDS 9538..9717 /gene="" /product="hypothetical protein" /translation="MIYYSQILCLPWRNFSLIFNTFNYSMDLHASMKDWGYPAKGRKG NGSYSGKAQGLRIDM" gene complement(10072..10461) /gene="" /locus_tag="" /db_xref="784761..785150" CDS complement(10072..10461) /gene="" /product="hypothetical protein" /translation="VSEVLNYTLQEIHEGKYKIETDEENLELILHPVLLKVFKKDDKY SFVVQNIISVNTDKPRFGPLCSSNTLNSRPARIRKTEVLNEPKIVLKIDEKIFNIIVN VTNISIYPDYRDSFGSPCVMVSTVVLY" gene complement(10454..10720) /gene="" /locus_tag="" /db_xref="785143..785409" CDS complement(10454..10720) /gene="" /product="hypothetical protein" /translation="MEEWGISQSGSQISTNFQSLSFSSAPFQVLVDNDFGNLIVEFKR SVEKSFEGEAFVTIGVDENGRISYISIEPLDKDLKEGIKGIKSE" gene 11006..11476 /gene="" /locus_tag="" /db_xref="785695..786165" CDS 11006..11476 /gene="" /product="PaREP1 domain protein" /translation="MEELIKKAEDIGINVEDVLISLISKNDPKEEIKLRLDLAKKYMK ECEEYLKKNDPVQASEKAYKVAEELIKALSEKFNLEEYQKTLKEGRWYAYLLVSASSK LSQKLGDWVLSGWDAGYSLHVWGFHEAKLAINDILPRVEKVRKMLEESEKILAN" gene complement(11682..12092) /gene="" /locus_tag="" /db_xref="786371..786781" CDS complement(11682..12092) /gene="" /product="PIN-domain protein" /translation="VKLKVLVDTNIIIEKRNKLFNLLGSYDPVYSDLVLVEVMEVIRK NALEAMKKNKREVANKYLAFGREFLKMLYQQNVQLEYPNIKDFVEAFEVMKDKDVDAV DAVLAVIAKRQGVNVLSNDKDWDRLKDYAKRVNI" gene complement(12095..12607) /gene="" /locus_tag="" /db_xref="786784..787296" CDS complement(12095..12607) /gene="" /product="hypothetical protein" /translation="LTREKLREIESLRSTTEILNNILLMTTTYLQSLYPISSLYAPPF RVLRIEYDNEGNPIYFTTYGDWLKYVRDSNLEETVLPDVNSLDLEEVMKDLGWEYKIE IKHNLTPVDQEAKIIYLSDCSLVKRVEYIVLSLTLINGLGEEIIPVCGEFTMDKYKGH LSQQLYWLSK" gene complement(12610..13209) /gene="" /locus_tag="" /db_xref="787299..787898" CDS complement(12610..13209) /gene="" /product="hypothetical protein" /translation="MTEFRYASVSLITNSSKDAILKVLSNDKVNLKLPLISVSESLYP NVPVPSSLLTTITYDDLQLLIYEVSFTEKKKIILQAALGKTTDEKVEDAILKLSELGK LLNIDYLIEVMLIYVLDVELRGLSKYKKAGYVLLDYSNEGDLRESEYLSSINVLPYVL DTRKSLVEIIYRNRQVSVDVIKSLINEIEKIVRGDEKLA" gene complement(13494..14453) /gene="" /locus_tag="" /db_xref="788183..789142" gene complement(14522..15523) /gene="" /locus_tag="" /db_xref="789211..790212" gene complement(15748..16443) /gene="" /locus_tag="" /db_xref="790437..791132" CDS complement(15748..16443) /gene="" /product="nitroreductase family" /translation="MDVFEEFYLKTQNFTFTLIPDNYPKVYEGVKVISLPKPREIREN FQRVITSRSSTRKFKEEKVDIHTISDLLYYSVGVRKKDSEIIYRMFPSAGGLAETEVY LIPFISDLEIGVYHYNPLYHSLEKLNNEIQLEILKSNIVSSIPDINTIPLLIILTTRY WKVLVKYGNRGARFALIDAGIVMENLYLVATALSLGICAVGGFNDYILNTALNLKEGE AVIGVLVVGKKME" gene complement(16453..17751) /gene="" /locus_tag="" /db_xref="791142..792440" CDS complement(16453..17751) /gene="" /product="hypothetical protein" /translation="MQDLINEFLGPAFGYTIEKYDNIIITKLLNYVNYELLESELATQ YIKARYTKNFPVEFTPLLRYLKDIVPAGGKGEKEEESLKGAIGEFLERFYGYMTFFDD NTSIFGKVAEIKEKFDILPTSYKFFSREQLKKLFFFKDYSDEAVITFTRATSYKDNKT VYVPSQIIYLTDLIKPGEDLIAYSTTGGLSYHEDFEKAFIHGLLEYLERDAINISWIS RISPLRIRIPERLKRKYKVLENEDVICLRFINEFKGLFVIGCLGFINGFYVGGASADI TVENALRRAIYEVYQSISSFSKISEEEVKLAKKLTPDLLIDFWLVPLYYTYVRKDFLL NYLSSLKSINYEELEREESLSYKELIGEVLSQYKIIYKDFNVEKYIGRGKLVRVMVPD LTPAHTPDMPFLGHQRYYTIRKKIGLSEVELFTEEPVPFP" gene complement(17739..18281) /gene="" /locus_tag="" /db_xref="792428..792970" CDS complement(17739..18281) /gene="" /product="hypothetical protein" /translation="MSLNTEELKEIRMLVPEKEEKINAVINRIRFHYPQFVNVFNSIE EVPENEKVLIVSSSIHFLVSQPIDLTRFKKVLIAYIMDPYRFFIYVVNKKAIPCMYEI YLWLKNSRLILDVKVDGVMIKEATPALSDFSELLLLGFSKMLFNSDKFGGKLVYVDVM EGELIINTPLKIPGCPKCKI" ORIGIN 1 atgtttgaga taatgcttta tgaatggaga agggcaatag ctaggaagaa ggttatagta 61 ctatctataa taacgtttat atttgagctt gggacttatt tagcaatata cttagcacct 121 tcacactcac ttaagacctt aataatccct ctctctcctt atttatgggc tcttggagta 181 ttattaccac aagtgctcct aatacacttc ttagcaatat caatagcttc tggatcgatg 241 gcagaggagt atgaacaagg aacagtggat tatttcatat caaaaccaat aacgaggttg 301 aggtttatta tggagaagtg gcttggttca ttctccttac ttttaatcat ttacctattc 361 atggtagtgc ttgccttaat cctttcatct cttctctttg gagtacaaag tgagttaata 421 gtattacctg agcttttctt ttcgataata ttctcaacac tagttttcct caacattgcc 481 tttgcaatag gtgaaatact aaggaggagc aatctatcct ttacaattag tggatttatc 541 ttaatagcct caataatagt atctgacgta cttatcttcg tgtctgtaat aacgcacaac 601 agcaactatg aaacgatttc tgagtactta ccaacttggg gttccacgga gttaccattt 661 atgctattac agaactctcc attatcagca atagctagag gactgaacat tttaccttcc 721 ataagcaata atgtgagttt agcaattgtg tcgattgttg tctactccct tcttccctta 781 gttttatcga taataaattt tctgggaaga gacatatcga agaaggtaag ttagtgagat 841 catctggcaa tccagtattg attaaaacgt acttgttatc ctcgggttct taaaagaaaa 901 gagtagaatg ataatccata ccactagtat ttccgaaaag tttatagcct agtattacca 961 aattgaatta tgcaagattt agttaaagct tacgaggaag agaaggacgc gaggattaag 1021 gagaggattc ttgcggtgaa gctgcatgtg gttgacggta aatcggagaa agaagtttcg 1081 aaaatgctga acaagggtta ttccacaata aaattgtggg ttggcaagta caagaaagaa 1141 ggtcttgacg gactaagaga taaacctaga tcaggaagac caagaaaagc tgaggaagaa 1201 aaaataaaac aaatactaga agactagcct caaaaatacg gaatacaaga agagtactgg 1261 acaatgagaa cactaaaaat aaaacaacaa ggaatagagt acaagaaatc caggctatac 1321 gagatagttc acgaactagg atacaatcta gtaaaaccta ggcctactaa cgttcaagca 1381 agaaaggaca tgtgggaaga ctttaaaaaa aataaagaag ttggaagaag aggctctctt 1441 ctttctagac gagagtaggg cagtaattag cacgtcgatc cggaaggttt taagattggt 1501 agtaagcccg taatgcacgt caatataggt ttttcttcga tctatgtcat tcttgctgta 1561 aacgcttgga ctggtgaagt agttgtttct cttgttagga ggcctaattc tgagtctgtt 1621 aagtacttct tgaggtactt taagagacgt tttggtagtg gaagggtcta catggttatg 1681 gataattatt ctcctcataa gactaagggt acgcttgagg tttgtcgtag gaagggcatt 1741 catcccatat ttactcctcc ttattcgccc gagcttaaca tggccgaggc agtcttcaag 1801 tccctcaagg aatacatgag caataaaata ttttatacga tagaagacgt taaaaaactg 1861 tattaagcag ttctttgagg aaaataagta taagtttaat cttaatgcaa taacatactt 1921 agaattagat aaaactgaac gctaagaact tcccggaaat actagtgtta atttatcccg 1981 agcataggta tatagattta gacagaaacg gaaaacagaa aagtggtata attcctccta 2041 acgtggtagt agggaatgca tttaactctt ttagcttttt ccttgaagct ccaagaccta 2101 taagttggga ggacggtaga gatttggaaa aggtctggaa attttattcc ctagttagac 2161 cagatatgct aatttatgaa ggaattgagg tagatattgt agattttaac ggtgatattc 2221 ccataaagag gccacattat atagttgaat ttaaggagtt ggagaactgg tggaaaaggt 2281 ggagatatct taaggactat aagccattaa gcggtaatga gtggagagct agatggttaa 2341 agggactcta tgagggctta gctgaggtat tgggcgttaa ggaaaaagaa ttaccgtcct 2401 tctctgaagg agagactaaa agacttaagg aatataaggt gatagagtta tataaggcta 2461 tctataggcc taagaagggt atggtaataa gtagagtgag tgtcgatatt actgtaaaag 2521 atgatttagg tgaaggaatt atcttagtgg atgacgttag attcgattat aataaactta 2581 aggatattgt agacgagtta actaacacaa atagtgtaga aaacgttgat attagggagt 2641 tagcttataa gttcgcgtta agtaaaagag atgaattcat agcgtggtta aagtcacaag 2701 ggatttcctt aagtttataa taaattcatg aaatgatttt aaattatata aaatagtaaa 2761 gtgctaaaat ctataccaat tattttacac catattaaca atactgttta tggactaaaa 2821 gttaatttga taactaattt gaaagtgttt acatttagct acatttatga gaatttcacg 2881 caaagtgtaa cgataagtaa gtttttataa ctacacttat tcattagtaa cttaatattt 2941 cactatcatt agttcatgaa aaattattta tataaaaaat taattaaaat tatatgcata 3001 ataaattaaa gaatactgta tttaattact atcaagcact gatcatcacc aaaaaattat 3061 ttaccttaaa accaaaatta ataactgatg ttaatccttg ccacgttagg atctgataaa 3121 tcagttacca caattaacgc aatattaacg gaaattttta ctggattgaa tccaaataag 3181 attataatat ttagggagga tcctcaaaaa aaggacatta aagggatgga aaaagcatta 3241 gagtatttgg gcgtgaatac attgatagag gagaaggtca taggagaggg tattaagctg 3301 tggagagaga agataagaaa cgaggagatt gacatatttg atattacacc agggagaaaa 3361 tatatggcat taagtgcaac ctattacagt agggctgaag aaattagata cgtttattta 3421 aaggacgaaa gggagggtta taatatattt ggttacgttc ccttcgaaca attaaaagtc 3481 ataaacgtta ggattgggga tgaaatacct tacgatccac ctttaacgca aaacgtgaac 3541 gaggctgaga gtttattaga tgttgattca cttagagcct tcataaatat tttaggactt 3601 catggcaaag tagagataaa tggcatagat ctagaaaatc ctgaccaggt tgaagagatt 3661 tgtttattta gatctggaaa atataaatac gaagaggaga aggacataat taaagaggca 3721 gagagaggaa gtttattctt agctgacacc aatgtttata ttagactagg taataggtta 3781 aggagtttag tttataatag aaaatatggt tttagactac tttcatctaa gaacacattt 3841 aatgagcttt ataatcatac tgctcaagat actcagaaaa ttgacgaaaa taaggtaaaa 3901 ttcattttag gaatgttaag ttataggtca cttcacgtcc ctcctataac atcacaagtt 3961 agatcatcag gagatatggg attaataaat gaggcgttag agataaagaa aaatgtagag 4021 gataacgtgg tattaataac tgcagataag gctttaggcc ttacagcgca aagtaaagga 4081 ctaaggacta taattctgag taaggtaaga aaggaaattg gagaatggga tataggtgaa 4141 ttattattct gtctcagttt ctataacgat tatcgtaacg gcattaggag aatgatagaa 4201 ataagcctta acggaagtaa aattgcagag ctgcactctt attatcatct ccaagagaga 4261 agggtaaaag ttagagtagt cgataaaaga tataattatc ctaaaattct agaaatttta 4321 tcagaaattt tagctactta ataaggaata atagtataga taatattatt atcactacac 4381 ttattattat tattagaggt aacatttgaa taggaacagt agacgataat atcatctcta 4441 catcatacga tattattgta aggtaaacaa gcgttgctcc acttataagt aatactatta 4501 gtattacgat atttttatcg ttaagtttca tatgtgattg tattacccaa gggatattta 4561 aatctaggcg gatatacgat caactcttca gataatgatg gcgtagttcc aggagaattc 4621 gctttcagtt tctacagaag tactttacca gatgagaaaa acgtcgagga tgaaatcaga 4681 agtatagtaa gtaaggctgc aaataacgta aatgtcaaat acgaaatgga ggttaagtct 4741 tatgttcctg gatcacttac ccccaaggat tctaagttag taaaagtagc ggaggaatgt 4801 gtatataggg ttataaacgt attaccggag acgataatag cacaaatcag atatgatggt 4861 gttttcttca gacctttcgc tgaggtcata aatataggac ccggggataa cgcacacata 4921 cctaacgaga gtgtaagtaa catagttaaa actagtagga tatatggttg tattatctct 4981 acgttatttc taagggatta atcttttgtc aattaactaa ataactgaga aaattaatat 5041 ataccaaaaa ttaagaatat tttataaaaa attttataaa ttatttttaa attttagatt 5101 aatatggaaa atatattaat aagagttaaa ataggtaaaa cgaggtctaa gctattgcag 5161 tagccaatag tgccaagtta atatagataa gcttttaata taagtttaaa cataagttta 5221 aacatggcaa agactataac tatatcaaac aaagcatatg aagcccttct taaggagaag 5281 aaagaagggg aaagtttttc agatgtaata attaggttaa catctagtgg aaataaggag 5341 aaattactta aatttgcagg aatttggaaa gacgccaaaa tagacgatgt aatgaaagaa 5401 ttagaagaaa tgtggtccaa atggaatgtt tagatagtga tatcataata gacttcttga 5461 agggaagaga cgaggcagta aattatataa aaaagagtaa agaagaatta gctataactt 5521 ctataaatgt ttttgaggtt tattttggag gatataagat aggtaagacg aaatgcctag 5581 aagacttctt ttcctcgctt aaaatcttaa cgttagatta taacgcgtca aagaaagctg 5641 cggaaattgg aactaaatta tcgaatgaag gaaggcaaat tgaagtaaaa gatttgctta 5701 tcgcatctat ttgtatagtt aatggttgca cactagttac atctaatatt aaacatttct 5761 cgagaataaa cgaattgaag ttaaagaatt ggagaaatga agttttttat tgaggttata 5821 aaacaataac ttttactcct tctttctcag caaattcctt aaccttatca gctgcagtta 5881 ttaaataata gttaaggtct ttagccaaaa gtactgcttc agtttcctca acgcttaacc 5941 cttctaaagg ttggaattta tcttaacaag gggttcaaag ggggcgaaag accccttccg 6001 tgagggagga gatggatagc ccccttattt aaataattct ttttcaaata ttctattaat 6061 gtctgacgta gggttacgct ttagagctta cgctgacgaa caaacattga gggcgttaaa 6121 agcccaattg aggttagcgt gtgaagtgta caacacccta cgttgggcag acatctattt 6181 tcatgagaga gacggaaaag gactcactaa gacggagttg agacaactag ctctcgatct 6241 aagaaaacag gataaacaat atcaacatct atattcccaa acactacaac agatcgcaga 6301 cagattctac gacgctagac agaggttctt cgaagggtta gcacacttcc ccaaggaaaa 6361 gaaagcacac aagtggtact cactagtata ccctcagtca ggttggaaag tcatgaaggt 6421 gagagaaata aggacgaaaa gcaagaagaa caagaagaag gtaatgacgc ttcagctttc 6481 aaacctaggt atcttcaacg tcgttgttca tagggatttc caactggaaa aagtggagag 6541 ggtagtagtc aagctggcac cttcaggcag attgtacatc actttcgttg tggatcaaga 6601 gtatcctcaa ctccccaaga caaacaaagt tgttgctgtg gacgttggtg tagagaaact 6661 tctcactacc tctgacgggg aatacgtgcc aaacatgagg ccttacgaga aggcactcaa 6721 caagatgaag aggcttcata aagctctttc aaggaagaag ttcttgtcac acaactggtt 6781 taaggcaaag gttaagcttg caagggctta tgagcacttg aagaacctga ggatggatat 6841 gtacatgaaa ctggggaagt attttgctga gcattatgat gttctcgtaa tggaggatat 6901 tcatgttaag caaattgttg gtaagtctct cagaaggctg aggatgaggt tgcacgatgt 6961 tgcttttcat gagtttagga gtattatgga gtatcaagtt gggaagtatg gtaaggagat 7021 tcgttttgtt aatcctgctt ttacttcaat gatttgtgct aggtgtggtt acgttaagaa 7081 ggacttggct ttggctgacc gtgtgtttgt ctgtccttcc tgcggttgga ctgtagaccg 7141 tgattataat gcttctctta atattctgag tagatcgggg ttggaacgac ccttagtgcc 7201 tgtggagctg agacctctac ctttggcaag cctcggctgt gaagcaggaa gccacgtccg 7261 ttagggcgtg gtagttcacg agagtaaacc aaaaccttga ctccttcatc caaagcctta 7321 ttaacatcta tcccttcctt tagtgcaaga gataagccag aggtcgtaat tattaaggaa 7381 tattttcttt taaacttttc aacaatcttg tccaatcttt taaaaaagat ttggagatat 7441 aaccggagtg tggacaataa ttttgttaat ccagtacaaa ttatataaag tataaattta 7501 ttttcaattc accacaagat ttgttagtta ataaaatata atattgcaat tttaaccatg 7561 ttcaaaagtt ttattgtaaa tcagagagtt taaatgatac gactttaagg aaattttaac 7621 caaatttcaa atgaacgaaa ttgttgtcca cactcgtccc aagtatagca actaatatta 7681 aaaccctttt aaacaacctg agtaattatt ataatatgaa taaagttcac gttagtgctg 7741 taggaacttc actattgaag aactcattat ctgcagataa cgtgaaaaaa gaggtggaag 7801 acctaggcct taaagattgg gatcgactta agtttgacga cgataggcaa aataagatta 7861 gggataattt tacaactctt aaagatctct tgcttaattt cttaaaaagt aaaggaaaag 7921 aagcctcagc tgaactagat tcgctacttt ctgctattga gaaattgcaa cataaaaagg 7981 aagagcttta cgtgtttctt tacactacta acacgtggaa ctctaaactt gcaggagagg 8041 taattaaaaa ttatttagaa gaagaaggga taaagtcgga gttggctacc gtaaagtcta 8101 tttcctctga agagaccttc catgaaggca tagaagatct attcgataaa gtgatataca 8161 aaatcttaaa atttaaggaa gaaggaaaag aagtttacat taacgcaacc gcaggcttaa 8221 agcccgagac cacattcctc acattagcag gacttttggc cggagcagat ttggtctatt 8281 ataaatatca agagtttaac gatgtagtct ttcttccttc acctccaata actatcagcc 8341 ctagatatct ggaatggtta attgaatttg ccaactacgg ctatactcta tcagagaaga 8401 aggcagaaga attgggaatt ccagtaaggc ttctcgaggt aaggaatctt gttgaaagaa 8461 aaggcgaaga tgcttataga ctgaaagatt gggtgagaaa gatgttaggt atttacttgc 8521 ccgcaggagt tactagcatg tactataagg taattgtgga aggtgaagaa gagaaagtgt 8581 tcgataacga gaccgaagcc tacaattata tggagaaaaa gagaaaggaa ggaaagagag 8641 taagagttga agttccaaat aaggtgtatt tccttggact ttgagttaga gattgaaggc 8701 gtgaaaatta aggctaaaat agacactggg tttgatggag aaataatagt aaataaagaa 8761 gttttcgaca agattccata cgatccttct caagggccta gaatatgcac agcctctatg 8821 gaatgctatt ccacgtacgt taaattggct aagataaagt atttagggaa agaagttata 8881 tcgactgtcc ttaactcgcc ggttatagaa aagaatatag tgggagaagg acttttaagg 8941 aaagtaggag cgataataaa ctataaagac aatacgatag aagatatata aagaagaagg 9001 aagtatattg tacaaatacg attttagatt gcaagttata actgctatct aaatcttact 9061 ttttatgtga aaaagaagcc tatttctatc aataatttgc agacaaaaga gttaagcgcg 9121 gtatctttat tattctaaaa ggaaacttag taatatgatt aataaaataa caataaggaa 9181 ctttaagagc cttgaaagcg tagatgttga tcttaagaaa attaatgttt tgatagggcc 9241 taacggttcg ggcaagacag cgtttgtcga atctctttta ttatcgagaa atataatttc 9301 taagctttta ggctattcac cgtttggcat gtggtggggt tatgaaaacg tagtttataa 9361 aagagataca tcaagaagta tagtcataga gtttaaaatt ttctagaatt aatacgccat 9421 gggtcagcta attttcttaa attaatatga gaaggatgag ctctaagttc aacatttaat 9481 taaaaagttt aagcttattc tagccaacta aatccttact aaaaagcgct agagaaaatg 9541 atttattaca gtcaaatatt gtgtttaccg tggcgtaatt tctccttaat ttttaatact 9601 ttcaattact ccatggattt acatgcatcc atgaaagatt ggggttatcc cgctaagggg 9661 cggaagggta acggaagtta ctctggtaaa gcccaagggc taagaattga tatgtaatcc 9721 tatgaagtcc aaacccctaa gttacaatgt tagataataa atatatatta cggtctttcg 9781 gtaaagttag caaaatttct taattgttga cggtttatta gtaggaaata atgtgataat 9841 tcttctttta ttatcagact ggacaaaaac cacgataaga tataaacaat taaagcttaa 9901 ttttttacaa taactttcct catcattaag ttttttggca aatactttct catctttaca 9961 aaactcatca attactctcc gaatttcacc tactatttct atcccgtaat ttttgcttag 10021 ttcttctaac ctaagtctta gcctttcttg ggcatgtatt gaaattcaca tttaatatag 10081 aaccaccgtt gagaccatta cgcatggcga gccaaatgaa tccctataat ctggataaat 10141 tgaaatatta gtaacattta ctataatgtt gaaaattttc tcatctattt tcaacacaat 10201 cttaggctca tttaaaacct cagtcttcct aatccgtgca ggcctggaat ttaaagtatt 10261 actagaacaa agagggccaa atcttggttt atcagtattc acagatataa tgttctgaac 10321 gacgaaagag tatttatcat ccttcttgaa cactttgagc aaaacagggt ggagaattaa 10381 ctctaagttt tcttcatcgg tttctatctt gtacttcccc tcatgaattt cttgtaaggt 10441 atagtttagg acttcactca cttttaattc cctttatacc ttcttttaga tctttatcca 10501 acggttctat tgagatataa gatatcctac cgttctcgtc gactccaata gtgacaaaag 10561 cctcaccttc aaagcttttc tcaacacttc tcttgaattc aactataaga ttaccaaaat 10621 cattatctac tagcacttga aaaggagcgc tagagaagga taaggactga aaattcgtgg 10681 aaatctgaga accggattga ctaattcccc actcttccat aattcctatt atgtactcta 10741 ggtattaaat tgttttgagc ataatgttgt cgttgacaaa ttaaacacaa gctcaattgt 10801 cttaacagtt tgcgtaaatt tccaatcaat agagtaaact catttatttt acacaaaaat 10861 atttaattaa tagttaaata attgaatcat cacgcgagag tttcaaactt tttagacagc 10921 tcaaaggctt ctctttattc gtactaatta tgtaagcact actagactaa aataatttat 10981 taattatcta tcacaattct cacatatgga ggagctaata aagaaggccg aagatatagg 11041 aattaacgtt gaagacgtac tgataagctt gataagcaag aatgatccta aagaggagat 11101 aaagcttagg cttgatcttg ctaagaagta tatgaaagaa tgcgaggagt acttaaagaa 11161 gaacgaccca gttcaagctt ctgaaaaggc ttataaagtt gcggaagagc taattaaggc 11221 tttgtctgag aagtttaacc ttgaagaata tcaaaaaacc ttgaaggaag gcagatggta 11281 tgcttacctc ctcgtgtcgg cttctagtaa gctctctcag aaattgggag actgggtatt 11341 gtcaggctgg gacgctgggt actcacttca cgtatggggt tttcatgagg cgaagcttgc 11401 aataaatgac attttaccga gagtagaaaa ggtaagaaaa atgcttgaag aaagtgaaaa 11461 aatacttgcc aattagtcat tgcttatcta aagtcatgga tatctaaatg atatttgatt 11521 aagtaatcta attaaaaggc aagaattatt aatattatat aaaccatact agtacagata 11581 actttattaa tttcatacaa atttttgtaa ctaaagagat aaaagagtta ttattttcaa 11641 ataaaatagt tattgacggt tatcttgccc tacatatgtt attatatgtt tacacgcttt 11701 gcgtaatcct ttagcctatc ccaatcctta tcgttagata gaacattaac tccttgcctt 11761 ttagcaatta cagcaagaac tgcatcaaca gcgtctacgt ctttatcttt catcacttca 11821 aatgcctcaa caaaatcctt tatgttcgga tattctaatt gaacattttg ctgatataac 11881 atcttcaaaa attctcgacc gaacgctaaa tatttattgg cgacttcccg tttatttttc 11941 ttcatagctt caagtgcatt tttccttatt acctccatca cttctacaag gacaagatcc 12001 gaatatactg gatcatagct cccaagtaag ttaaatagtt tatttctctt ttctataatt 12061 atattggtat caactagtac tttcaatttc accactactt agaaagccag tacagttgtt 12121 gcgagaggtg ccccttgtat ttatccatcg tgaactcccc gcatactgga ataatttcct 12181 cacctaagcc gttaatcaga gtcaatgaaa ggacaatgta ctccactctc tttactaagc 12241 tgcaatcgct caaatagatg atctttgcct cctgatctac aggagttagg ttatgcttta 12301 tttctatttt atattcccaa ccaaggtctt tcattacttc ttccagatcc aaagaattaa 12361 cgtcaggcaa aactgtctct tctaagttag agtccctcac gtatttcaac cagtctccat 12421 acgtcgtaaa atatattgga ttcccttcat tatcatattc tatacgcaat actctgaaag 12481 gtggtgcata taaactacta ataggatata aagattgtaa atatgtagta gtcattaata 12541 atatattatt tagtatttca gttgtagatc ttaaagactc tatctcgcgc aacttttctc 12601 tagtcaagct taagctaatt tttcatcacc tcttactatc ttctctatct catttattag 12661 acttttaatt acatctacgc ttacttgcct attcctataa attatttcga ctaaggattt 12721 cctcgtgtcg agaacataag gcaaaacatt tattgacgat aggtattcag actccctcaa 12781 gtcgccttcg ttactatagt ccaataacac gtagcctgcc tttttatatt tagataatcc 12841 gcgtaattct acgtccaaga cgtaaattaa cataacctca attaaatagt ctatatttaa 12901 caattttcct agctcagata acttcaaaat agcgtcctca actttctcat cagtagtttt 12961 acctaatgct gcctgcaaaa taattttctt cttctctgta aaggaaacct catatatcag 13021 taattgtaag tcgtcataag ttatagtagt aagaagggaa gaaggaacgg ggacgttagg 13081 atataatgac tcacttacag aaattaaagg caattttagg tttactttat cattagacag 13141 taccttcaaa attgcatcct tactagaatt agtaataagc gagacggaag cgtaacgaaa 13201 ctcagtcata attaaagttt agagtcaatt ctaataaagg ttaattagat ccatatcgac 13261 gttatttgta tattcattat ctgaagcaac gtaagtaatt tacactaacc gaatttacct 13321 gagaatgtcc ggaatgtaat tatctgaatg aatatataaa tggaatgata aatattaata 13381 ttatcagaag tataaaacct ggttaatctg gaaaaacttg atcatggaaa aatatcaagt 13441 taagaagatt tatttgtcat gcatggtgat gcttgagtgc gtgatgacgt ttcttagagt 13501 tgaactattc gacgtcctgg aggggttctc cgttggacgg ctaggaacat cctgatattg 13561 tagaagactc ccaggacgtg gaggaaggct tcgttcctcc acaccgtggt cccatagggc 13621 ctccagaact tgtacaggaa ggtaccgaag aactccacgt gggccctcag agtcgtgaaa 13681 ggtttctcca tagctatgag ctgggttggg gagggcgaga aacccctatc agctatctta 13741 atccccttga gcggggactt aaatctctca tccgagaagt tggcaggctt caccgtgatg 13801 gaccttacga agagggaagt ggagataact attagggcct tcagcccgaa gtgagagact 13861 cccctcttct tggtccactt ccccttgaat ctcctcttag ttctccccaa ggagagcagc 13921 ttcttggcct tcttcaagtt accttccttc ttctccagct ctgccttctc tcggaaggtc 13981 tccacgctcc tcttcccaaa aggtaagtct agaaggaagg agtcaacgag ccacgcaatg 14041 aagtccagga agtgggcact ggcagggagg taactgggta ggcacttctc ctcaagcttg 14101 aaggaaattt ccagcaactt cttccttact tcgtatactc ttcccacgaa atcgtgtaat 14161 gtgctcttgc ccactttcct cccaacgaac tacgccacaa cgacgttcac gttgaccatc 14221 tttaccgcgt ctctatagga acaggagtag agtaccatga cgattagtaa cttcaggtaa 14281 atcagagtgc cttctcctag aactctttct aaatctaggg tgtctagcac gggtttgata 14341 tccgttaacc atttttccct ccacggcata tcctctcttg gggggagaga atagtacact 14401 aagtttggga tgcgtcttag tgtacgtgcc atggtactac tctctcctcc cataacttaa 14461 gtattactac aatttaatcc aagataatgc taagaatcaa tttattctca aaaattaaaa 14521 ttcagttttt tacattccgg acactctctc gagcatagtc cacactactt acgcaagtga 14581 tgaaacctgc tttactcact agcgtcaaag ggcttattat aatacagcac agcccaagta 14641 ataacagcct agcacaagca gtaatcaact tcttacccct aagcctaccc ttatgatcct 14701 cataaaaacg cttaataata ggattaacct tgatagcagt caaagctgca agatagaaag 14761 ccctcctcaa aacagcatca cccctcttag aaatacctct caatacaaca ctcttaccac 14821 tagactcaac aaccgggtca agaccacaat aagcaacaaa cctcttctta tcactaaagc 14881 gcctaatatc accaacccta gccaaaataa tacaacccaa ggttttacca atacccggaa 14941 tagtgaaaat caaactatcc ttgggaacaa aattctcaag ctccttctca atctccctct 15001 tcctagcttc aagcctctcc aactcctcca aaagaaacct cagacaacac tataccatct 15061 ccactcctca aaacctcctc caaattcttc ctggacagac tatccctata gcctaaaagt 15121 accaaatccc tcctcagcct attcttaacc ctagcaatac tcctagtaac gaaatcccac 15181 tggctagtca actccctagc atcacttgtt gtaaacccac tacccatact tacaactatt 15241 tctgctagct ttttagcatc attcttatca ctcttcttac ccctaaaatc cttaaacttc 15301 ttgagaataa agggattaat aatcctaact cacccattaa gtactttgct aggttaacgt 15361 ggtaaactcc agtactttca atacccactt tgcaaccctt aggcaaaatc ttccttatct 15421 cctcaaaccc ttgcctatca ttaggaaact cgtagtattt accttgaaaa tacatgatta 15481 atttatcttt tgatacatct attcctgcaa ctggggcctc catgtatact cacccttatg 15541 ttttattcgg gcttcaagcc caacttccgg tttgaattgg aggctgccaa gctaacaacc 15601 gagctttaag cccaaagagg tcaacggcct acaccccagt cagatctgta ttacacagat 15661 ctgactaata tgttttatat aaggaagtca gttacggaga ctgttattca tgttgtcgag 15721 taacttatga tactatttcc taagttacta ttccatcttc tttcctacta ctaatactcc 15781 tattactgcc tcaccctcct tcaggttaag tgccgtatta agaatatagt cattaaaacc 15841 gccaacggca catataccca ggctgagtgc tgtagctact agatataagt tctccatgac 15901 tattcccgca tcaatcaacg caaacctcgc acctctgtta ccatacttta ccaagacttt 15961 ccaatacctc gtcgttaaga tgataagcaa cggaattgta ttaatatctg gaatagaact 16021 aacaatattt gacttaagaa tttctaactg aatctcgtta ttaagcttct ctagagagtg 16081 atacaacgga ttatagtgat atacacctat ttccaagtcg gatataaaag gaattaaata 16141 cacctcggtc tctgctaaac ctcctgctga aggaaacatt ctatatataa tctcactgtc 16201 tttcttccta actccgacag agtaataaag taagtcagaa atcgtatgaa tgtctacctt 16261 ttcttcctta aactttctcg ttgaagacct agaagtgatt actctctgaa agttttctct 16321 tatctcccta ggtttaggta gggatataac cttaacccct tcataaactt tcggataatt 16381 atctggaatt aacgtaaaag taaaattctg tgtctttagg taaaattcct caaatacatc 16441 catcacgacc acctaaggga atggtaccgg ttcttcggta aatagttcaa cctcactaag 16501 tcctatcttc ttccttatag tataatatct ctggtgacct aagaaaggca tgtctggagt 16561 atgggctggg gttaggtcag gaaccatcac cctaaccagt tttcccctac ctatatactt 16621 ctccacgtta aagtccttgt aaattatctt atattggctt agtacctctc caataagttc 16681 cttgtaactt aacgactctt ccctttctag ctcctcgtaa ttaatgcttt taaggctgct 16741 tagataattc aacagaaagt ctttcctaac atacgtgtag taaagcggga ctaaccagaa 16801 atcaattaaa agatctgggg tgagcttctt tgcaagttta acctcctctt cacttatttt 16861 actgaaggac gaaattgact gataaacttc gtaaattgct ctccttaacg cattttcaac 16921 agttatatct gcagacgcac ctccgacata aaatccgttg ataaaaccta aacaacctat 16981 gacgaaaagg cccttaaact cgttaataaa gcgtaagcaa ataacatctt cgttttcaag 17041 tactttatac ttccttttta gtctctctgg gatccgtatt ctcaaagggc ttatacgtga 17101 aatccatgaa atatttattg catccctctc caagtattct aacaatccat gaataaacgc 17161 tttttcgaaa tcttcatgat atgataatcc tccggtggta gagtatgcta ttagatcttc 17221 accgggcttt atcaaatctg ttaagtaaat tatctgcgag ggtacgtaaa ctgttttatt 17281 gtctttatag gatgtagctc tggtaaacgt tataactgcc tcatctgaat agtccttgaa 17341 aaagaataac ttcttgagtt gttctcttga aaagaacttg taactcgtag ggaggatatc 17401 aaacttctct tttatttctg caacttttcc gaaaatagat gtgttatcgt caaaaaaagt 17461 catataaccg taaaatcttt ctaagaactc tccaatagca cccttaagac tctcttcctc 17521 tttttccccc ttacctcctg caggcacgat atcttttaag taccttaaaa gcggtgtaaa 17581 ttcaacaggg aaatttttag tatatctagc cttaatatat tgagtagcta attcagattc 17641 taacagctca tagtttacat agtttaaaag ttttgtaatt ataatattat catatttttc 17701 tatggtataa ccgaaagcgg gtcctaaaaa ttcattaatt aaatcttgca tttagggcac 17761 cctggaatct ttaatggtgt atttattatt aattccccct ccattacgtc tacatatact 17821 aatttaccgc caaatttgtc gctgttaaaa agcatcttag aaaatcccaa taataacaac 17881 tctgagaaat cacttagggc aggtgtagct tcttttatca taacgccatc aacttttaca 17941 tccagaatta acctagaatt ctttagccat aagtatatct catacataca agggatggct 18001 ttcttattga caacgtatat gaaaaaccta tagggatcca ttatgtacgc tataaggact 18061 tttttaaacc ttgttaagtc aattggctga ctgacgagaa agtgaatact actcgagaca 18121 attaatacct tttcgttctc tggcacctct tcaattgaat taaagacatt aacgaactgc 18181 ggataatgaa atcttattct attaattact gcatttattt tctcctcctt ttccggtact 18241 aacattctaa tttctttcaa ctcctccgtg tttaatgaca ttaagttgtt aaattcatct 18301 tcactaaact ctattaaacc tgaagcttcc gaatatgcaa gatacttatt ataattttta 18361 aatattaaaa aaaaaaggtg atatggttag ggtaggatgc atagtacatg //