LOCUS NC_017276:4 19204 bp DNA linear BCT 09-SEP-2013 DEFINITION Sulfolobus islandicus REY15A chromosome, complete genome. ACCESSION NC_017276 SOURCE Sulfolobus islandicus REY15A chromosome, complete genome. COMMENT locus start: 362417; locus end: 381620 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.620704; n0_4mer:D = 19.574822; n0_4mer:PS = 26.592764 FEATURES Location/Qualifiers source 1..19204 /organism="Sulfolobus islandicus REY15A chromosome, complete genome." gene complement(1..1398) /gene="" /locus_tag="" /db_xref="362417..363814" CDS complement(1..1398) /gene="" /product="group 1 glycosyl transferase" /translation="MIVSVTAELGLDIGQNFAGGLGILEGDKFYAASRLSINYTVITL FYRRGYVNGEEKQKELLSNLNKEWESEITLGGQRIKVEYLAYTLNTAKAIFANPLNTK FNDQLYVENSDEERFYKCLLLARVAENYINERIGWDKVKYVDMQEACPAFLPLIRYFP SYRIIIHTPAPWGHPTFPSYLFKKEFGYEFPLDHVVMTDIGLSSSIEGIVVSKKMLKH VGRTFPQHMYKIRAVTNGVEIPRWRHPLLNDVKDLDDFIKKRKEVKRDIIKKLGKDTD KPTIAWLRRITAYKRPDFILRLIDDLKDDVFFIIGGLAHPKDYSAVEMERRLKEISEM KNNVIFVRGADANLMKLAIWASDIWTFTPFSGWEASGTSFMKAGINGVPSIASRDGAV PEIINDGYNGWLFGEDRETLLPLNVYDDNKEYEEFLKKIKLALSQFYEVGYNAYKTFP TYCAMDRLMKEYGYP" gene complement(1443..2036) /gene="" /locus_tag="" /db_xref="363859..364452" CDS complement(1443..2036) /gene="" /product="hypothetical protein" /translation="MKKAELLFNAYKSRKEIEPFPLTEDEAKKVKEEFIEILINSEGL GGYKLSGFGEGVLTKPMITRENTVELWFRNHKLEVEIVTLVENGEVKRTFLGLEIPAP RFTTWDLPSHYIVADNIFAARLYVGPEIDPPFGSFKLYINDKFVGEGEPKYKPEEKVK EYMKGYVSLGVFIGPTSVKKGDKIRVEGKKSISVSLI" gene 2128..3681 /gene="" /locus_tag="" /db_xref="364544..366097" CDS 2128..3681 /gene="" /product="aldehyde dehydrogenase" /translation="MVFVNEKTYQRYVEERREEEFHKEYERALNHIELGKEYPILIGK DEIKLSSKYIVKTPVDTSLTFAITQKDDGNNLRKAIKIARESFDYWQYSDWKDRVEFA YKAAEELRRRKFELAAIITYENGKNRYEAIAEVDETIDYFLYYAKLLEDNRGYIRQME GRIYKNEKAFSVMRPYGTWLIISPFNFPLAITATMTLGALLTGNTVVVKPSSDTPVSA YMLVTIMRRAGFPLEAVNYVTIPGELITPALDEVDGFAFTGSRDVGHKLLKTFINRKP RPAVLELGGKNATIITAKADLNKAIEGTFKGAFGYGGQKCSATSRAFVESPIYDEFLK RLKEKVEKTVIGDPRKRETFLGPIINKGAIEKFRRYVKQAVEEGGKILVGGRVIDDEK IYLVEPTIIVELPYSSPLWKTELFVPILLVKEVKSLEQAVKLANDVDYGLTAGIFSDD PKEIQYLFDHIEAGVVYANRTAGSTTGAMPGVQPFGGWKDSGWTGRNAGGPYYLLSFM REQARTVYD" gene complement(4140..4502) /gene="" /locus_tag="" /db_xref="366556..366918" CDS complement(4140..4502) /gene="" /product="VapC-type toxin" /translation="VTKEKGWNRITELLKDSETLDLALVEVSNVIWKKVVLTNEITPQ DANKAIMIVKEYLPQLLTVNKSVKLLERAIDISIREKLTIYDSLYIALAESKRSKLLT SDKKQYEVARKYVDSELF" gene complement(4525..4746) /gene="" /locus_tag="" /db_xref="366941..367162" CDS complement(4525..4746) /gene="" /product="VapB-type antitoxin" /translation="MKMVYSLRIDKELREEMEKYDIKWNEEIEGFIRKRLEELKKEEI LKRINEILSTMPETNSSSAEMVREDRDNN" gene complement(5591..6822) /gene="" /locus_tag="" /db_xref="368007..369238" gene complement(7313..7873) /gene="" /locus_tag="" /db_xref="369729..370289" CDS complement(7313..7873) /gene="" /product="LmbE family protein" /translation="MQVLIVAPHPDDETLCCGGVVQIFKERGYKVSVVVVTDGRYGSP DEKLKGSMELVEIRRQEALRASKILGIDEITFLSFEDSKVIEKEVEKALVEFLHDKDV VLSPIPFDSHPDHAKIGKVMEKLYPKAYFYLIWGSMQANWREVRFDIRKYREVKIRAI NEYKSQIGGLHLDRFTGDYEVFWMKV" gene complement(7878..9023) /gene="" /locus_tag="" /db_xref="370294..371439" CDS complement(7878..9023) /gene="" /product="group 1 glycosyl transferase" /translation="MNVLAVVDFGLNEKTGGYKRNLEIMKRLSRNINVDIIPSLRNVR LYSCRKDLITLLESLNSTPDYILELLEKSSGVEEFLNGLKTKRYDIAVVYSNSSENVR LARRITSAPIGVQLQLEPFYRDMTTLFKIKFRGITGRAVKKFKEAMEESKREEVKWKE LIERGDLNFAISVSKVPLINSSLDKLLSYRVTKPGNAFDEDLLKFRRERDKEDYAVYF TRLMPEKGLFEIPLIWKKLRRDVKLYVIGEFVDERDKDDFLSLIKRLDVNVEYVGFKE KEELYNTVAKAMFTVYPSHYDSFSLVILESLALGTPVFAYDTLALKEIYGNVKGVHLA REDDVKGLADLISNFKSEEVVPIPEEYSSWDKVAEAELEDIKAFAKR" gene 9178..9711 /gene="" /locus_tag="" /db_xref="371594..372127" CDS 9178..9711 /gene="" /product="Appr-1-p processing protein" /translation="MYKNPYGLEIHLIKGDITEMEADAIVNAANSYLQHGGGVAYAIV KKGGYVIQKESDEYVEKYGPVPVGEVAVTSAGKLKSKYVIHTVGPRYGIEGKDKLESA IFKSLLKADELSLTSIALPAISTGIYGYPYEICARVMANILKNYKAKSLRKVIVCLYS QDAYDIFKKVFDSILKS" gene complement(10097..11302) /gene="" /locus_tag="" /db_xref="372513..373718" CDS complement(10097..11302) /gene="" /product="IS200/IS605 family OrfB protein" /translation="MWRAKEKSDKIQLSFKYKIYPTREVEEKLIKVMQIEAKVYNALL DVVNNARKEGKKITPKDTQNMLKDLKIEGKELVYSKALQMVNNQLWYNINALHEQKKK GKKVGKLRYKKILKIINYNQSGFKVEGDKLTLSKIGEIKVLFHRPLEGEVKGVIIKKS STGWYAIFQVEVEKKPLEKTGKVVGIDLGVEKLVTTSDGVVIENPKVFDKVERRIKIL QKSLSRKKKGSRNYEKVRKKLAKLHEHVKNLMSDYIHKVTSWLVEEYDEIYVEDLDVK EMVEDGESKVLRKHILHSNFSKFVSYLSYKAERAGRRVVKVDPRNTSKTCAKCGYVKK DLALADRVFVCPKCGWAVDRDYNASLNILHAGSGQPLEPVDRGPLLYIPFSEGVYSRF PGRSRKSPS" gene complement(11277..11684) /gene="" /locus_tag="" /db_xref="373693..374100" CDS complement(11277..11684) /gene="" /product="IS200/IS605 family OrfA transposase" /translation="MRYRLDRGSHSVYALYYHYVQVVKYRRKVFDNEEIINFLKEQIQ EISKTFEVEVIDIGVDKDHFHMLFKAKPTLNIPRYVNAIKTITSREIQRKFPQVKEKL WKGHFWSPSYFLATSGQVTLEVLKKYVESQGEE" gene 11791..11964 /gene="" /locus_tag="" /db_xref="374207..374380" CDS 11791..11964 /gene="" /product="flavohemoprotein" /translation="VARSHVRAGIKPEQYPLVGELSLDAIKEILNPPEEVLKAWEKAY NYLTKILREKEQK" gene complement(11991..13046) /gene="" /locus_tag="" /db_xref="374407..375462" CDS complement(11991..13046) /gene="" /product="ATPase" /translation="VLVIYFDFKPKETKEDLFDREEELKKLLSSKDDSIILLTGIRRI GKTSLLKVFLNESKLPYALVDVRYPLTSYRSLYTIFSNVLSQLNKERRVAEVLKYVKG ISLFGINISLSWDPKNRPSLLEIMDKVDESVKVIIAFDEAQNLRGKLANVFLSILAHC YDYCKNVTFILTGSEIGLLYDFLKIDDPSSPLYGRHVEEIRLKRFSNEKSLEFLREGF RQANISPNESVLEYAVSKLDGIVGWLTEFGYRCVKIGEVKREIVDEILEIASKLAMEE LSHFSKDYVIVIEAIAKGHSRWSELKRYLEDKKKRVVYDAELKRYLDKLEKMGYVVKK ESREYDLADPVLKNALA" gene complement(13439..14344) /gene="" /locus_tag="" /db_xref="375855..376760" gene complement(14722..14901) /gene="" /locus_tag="" /db_xref="377138..377317" CDS complement(14722..14901) /gene="" /product="hypothetical protein" /translation="MRSILKIIVGVTMLSGAIGLDYIGASFQSLSVLVVSMILAIAGA MVGIRGLMEFLGERF" gene complement(14917..15894) /gene="" /locus_tag="" /db_xref="377333..378310" CDS complement(14917..15894) /gene="" /product="oligopeptide/dipeptide ABC transporter ATPase" /translation="MVMRLHVGSISNYIVKVENLKVYFTKGGIFSKKYIVKALDNVTL SIKEKEVMGVVGESGSGKTTLGRVTIGLQKPTAGDIYIRVDKREINVNKAKLKDISKY VQMIYQDPYSSIDPIMRVYDVLAMPLKYKKEIDIDGKIEEAMRLVDLPLELLENRVYQ LSGGQRQRLSIARAIVVNPKYIVADEPTTMLDASLKGEILKIIKDARESKGFSFMLIT HELPIAKIISDRIAVLYLGKVVELGNSNEIIKNPLHPYTQGLIEVYPRIDPSLRDKMK EIKIKVDIVRPDKGCVFYPRCPFAMPKCKEQEPALKEISPGHYVACWLY" gene complement(15863..16801) /gene="" /locus_tag="" /db_xref="378279..379217" CDS complement(15863..16801) /gene="" /product="oligopeptide/dipeptide ABC transporter ATPase" /translation="MLLEVRNLKVYFYTKRGIVKAVDDVNLYLDKGEIIGLAGESGSG KSTIGYTIMRLVPFPGKIEGGEILFKGENILKLDEETFRKNYRWKKIAMIFQGSMSGF TPVFKIRDQIIEVLRIHGWTGDYDKRVEELFKMVNMDPQLAEKYPHELSGGQKQRAFI AMALALNPEILIADEPTTALDVMVQEHILNLLKKLRKELNLSIIFITHDLALLSEISD RDYMLYAGKVMESGPSEVIFKKPRHPYTSLLVESIATLDKDIIKGIPGSMPDLSNPPV GCRFNTRCPFARDICFKEEPKMKAFSDGDEVACWLY" gene complement(16803..18155) /gene="" /locus_tag="" /db_xref="379219..380571" CDS complement(16803..18155) /gene="" /product="dipeptide/oligopeptide/nickel ABC transporter permease" /translation="LSKRHIGFSSYLRDFLSSKIGLVGLIILIILLIFTGIAISIPAK VYASWNNPASWNQYPEHVPPAWLSIFYPNKYFTTEELSPINISLYSPAKNIFVAIITY QFNWSKVLPAYNVYFIVSTNITPIEEVIYWSKPDGYTLQINVPNGVFNVPFDLTSIRG DILNYISSITGKTPNIVNSTVLSSALFNSPKSNFTTTEQGRYVVKIEIVSSSPMNITK SRLLLLGNSYGLMGTDYFGRPLDLGVLLGLPNALEIGALTSLVAVLVGIFVGGISGYL GGNKDSAIQWLTLVFLALPALPFLVAVSFVTEPNLEIEALLIAFLSWPFYAIIARSMA LSIKSNSFVEADKLLGIPSYRVFFTHFMPRLIPITVAYMALGVPAGILLAQTLAFLGI APANIVTWGGILDAAETYQAQVNGWWWWVVFPGAMIVIVAIPFVLIGFAIERVTLGER" gene complement(18158..19204) /gene="" /locus_tag="" /db_xref="380574..381620" CDS complement(18158..19204) /gene="" /product="dipeptide/oligopeptide/nickel ABC transporter permease" /translation="MGFTTYMIKKVLIYFSVLLATLTILYIFTFPILQEVIAKSINFQ VAQFSQTLFKNAHNLNSTQIQIAVEKYRESLIAAYGLNQPIIDKYFIQMYNLMRFDFG TAYFLQAPSGSREVSSIIAYYLPNTILLFTTATIVFIVAGTIIGLLSAKSKFWEKVIA IIAVIHSSIPTWWLGFVLIAALAYAVKVFPPGGMTSVPPPKNPFDYGISVLYHMSLPL ITIFIVNVGGFAYIVRSLVTSIMKEDFVITAKARGLPDSRILYRHVLRSASPSIATQA ILALAGSLGGSLTTEVVFEWPGVGLLTYVAITLNDLPVILGITYVLTIVLLLGLFLGE LVYGLLDPRIKVGE" ORIGIN 1 ttaaggatat ccgtactctt tcatgagcct atccatggcg caataggtcg gaaacgtctt 61 ataagcgtta tatcccacct cgtaaaattg acttaacgct aacttgatct ttttgagaaa 121 ctcctcatac tccttgttat catcgtaaac gttcaatgga aggagagttt ccctatcttc 181 accaaaaagc catccattat agccgtcatt tattatctct gggacagcac catctctaga 241 cgctatagat gggactccat taattcctgc cttcatgaaa ctagtaccac tggcctccca 301 accggagaat ggtgtaaatg tccatatatc actggcccat atggcgagtt tcattaaatt 361 tgcatcagca ccccttacaa agattacatt gtttttcatt tcagaaattt cctttaatct 421 tctctccatt tccacagcag aataatcctt aggatgagct aatccgccta ttataaagaa 481 aacgtcgtcc tttaaatcat caattaatct taaaatgaaa tctggtctct tatacgctgt 541 aatcctcctt aaccaagcta tggtaggttt atcagtatct tttcccaatt tcttaataat 601 atctctttta acttccttcc tctttttgat gaagtcgtcc agatctttaa cgtcattaag 661 taatggatgt ctccatcttg gaatttcaac tccattagtc actgccctta ttttatacat 721 gtgttgagga aaagttctac caacatgttt taacatcttt ttcgatacta caataccttc 781 tattgacgat gaaagtccaa tatctgtcat caccacgtga tctagaggaa actcataacc 841 gaactccttt ttaaacaaat atgaaggaaa ggtgggatgg ccccaaggtg caggtgtatg 901 aattataatt ctataactgg ggaaatacct tatgagtgga aggaaggctg gacaagcctc 961 ttgcatatca acgtatttta ccttatccca tcctattctt tcgttaatgt aattttccgc 1021 aaccctagct aatagaagac atttataaaa cctctcctcg tcgctattct ccacgtaaag 1081 ttgatcatta aacttagtgt ttaatggatt agcaaagata gcttttgcag tatttaaagt 1141 gtaagccaaa tattcaacct ttattctttg acctccaagg gtaatttcac tttcccattc 1201 cttatttaaa ttagataata gttctttttg tttttcctct ccgttaacat agcctcttct 1261 ataaaatagc gtaattactg tatagttaat acttaatcta gatgcagcgt aaaatttatc 1321 cccttcgaga atacctaggc ctccagcgaa attttgacca atgtccaagc caagctcagc 1381 tgtaacgctt acaatcatat ctctttgctt cctcaatgat agattaaaaa actatttgca 1441 aatcatatta gacttacgct tatacttttc ttaccctcca ctcttatctt atctcctttt 1501 ttaacgctag tcgggccaat aaatactccc aaggaaacgt aacccttcat gtactcctta 1561 accttttcct ctggcttata ttttggctca ccttctccta cgaacttatc gtttatataa 1621 agcttaaatg aaccgaaagg aggatcaatt tctggtccta catacaacct agctgcaaag 1681 atattatctg caacaatgta atgtgaaggg agatcccatg tagtaaacct tggagctgga 1741 atttccaatc ctaggaatgt ccttttaact tcgccgtttt caactagggt aactatctca 1801 acttctaatt tgtgatttct aaaccacaat tctaccgtat tttctctggt tatcattggc 1861 tttgtcaata ctccttcccc gaaaccagat aatttgtacc cgcctaaacc ctcgctattt 1921 ataagaatct ctataaattc ctccttaacc ttcttagcct catcttcagt taggggaaag 1981 ggttctatct ccttcctact cttgtatgcg ttaaataata actcagcttt tttcattaat 2041 atttaacgag aaaaattaga ttaaatattt ttcctagtca atatgtgagt ggaatagtct 2101 tatatcccta gctatcaaat attacacatg gtatttgtaa atgaaaaaac ttatcaaaga 2161 tatgtagagg agagaaggga ggaggaattt cataaggaat atgaaagagc gttaaatcat 2221 attgaacttg gaaaggagta tcctatcttg attggtaagg acgaaatcaa actttcatcc 2281 aagtatatag ttaaaactcc agttgacaca agtttaactt tcgcaattac tcaaaaggat 2341 gatggtaata atttacgtaa agcaataaag attgctaggg aatcctttga ttactggcaa 2401 tactcagatt ggaaagatag ggtagagttt gcatataaag cagctgagga gttaaggaga 2461 agaaagttcg agcttgccgc aataataact tacgaaaacg gtaaaaacag atatgaagca 2521 atagcagaag tagacgaaac cattgattac tttctctatt acgctaagct tttagaggat 2581 aataggggat acataagaca gatggaaggt aggatataca agaatgaaaa agcattttcg 2641 gtaatgagac cttatggtac ttggttaata atttccccat tcaactttcc attagccatc 2701 actgccacaa tgactttagg agcactactg actggaaata cagtagtagt gaagccgtca 2761 tcagatactc ccgtttcagc ctatatgctt gtaaccatta tgagaagagc gggattccca 2821 cttgaagcag taaattacgt cacaataccc ggagagctta taacaccagc cttggatgag 2881 gttgacggtt tcgcatttac gggttctagg gatgttggac acaaattgct aaagacgttt 2941 ataaatagga agccaagacc agctgttctc gaattgggcg gaaagaatgc tacaataatt 3001 accgcaaagg ccgatttaaa taaggcgatt gaaggtactt ttaaaggtgc tttcgggtat 3061 ggagggcaaa aatgcagtgc aacttctagg gcatttgttg agagtccaat atatgacgag 3121 ttcttgaaga gactaaagga aaaggttgag aagactgtaa taggcgatcc gaggaagagg 3181 gagacctttt taggtccaat aataaataag ggggctattg aaaagtttag aagatatgtt 3241 aaacaagcag ttgaagaggg tggtaaaata ctggtgggag gaagggtaat tgatgatgaa 3301 aagatctatc tagtggagcc gacgataatt gtggaattac catactcaag tccattgtgg 3361 aagactgaac tattcgtacc aatcttacta gtaaaggagg tcaaaagcct tgaacaagct 3421 gtgaaactcg ccaacgatgt tgattatggc ttgactgcag gtatcttctc tgatgatccc 3481 aaggagatac aatatttgtt tgaccatatt gaagctggag ttgtctatgc taatagaact 3541 gctggatcta ccactggagc tatgccggga gtacagccat ttggaggttg gaaggattcg 3601 ggttggactg gaagaaatgc tggaggtcca tattatctcc tctcgttcat gagagaacaa 3661 gctaggacag tatacgatta aggtaacctt tttattagta aactttcata tcaattagtg 3721 aataagatgc tttcagtatt ttctggagcg actcatggat cccataatga acttcttggg 3781 gtagtatgta gcctcacttg taataattgg attagctgta acgattaaca aagagagaag 3841 agaggaaaaa caatatcttt ttccttgcct acttcctttt ttgacttaat tttctcgttc 3901 acgccaagcc taagcttctc taaccgttat taattgagac tttagcttca ctgtttgtta 3961 cctaaatata tacacttttc ccatatttca agaaaacttc ctcctcttct tactgttatt 4021 atttattctt gtgataaacg ttagtgaaag ctatagtctt taaaaccttt gtaagatcaa 4081 gcaacactat catatattat cagttaaaat tttcttttct gcacaattta ggtcttagtc 4141 taaaataatt ccgagtccac gtattttctt gcaacctcat attgcttttt atcgctggtt 4201 aataatttac ttctcttgct ttccgctaag gcaatatata gcgagtcgta tatagtcagt 4261 ttttccctta tagagatatc tatagctctt tccaagagtt taacgctttt atttacagtc 4321 agcaattgag gtagatattc cttaacaatc ataatcgcct tattggcatc ctgtggagta 4381 atctcgtttg ttaacaccac tttcttccaa ataacattgg aaacttctac tagcgccaga 4441 tctagagttt cactatcctt tagtaactcc gtaattctat tccatccctt ctccttagtc 4501 acgtattttg ctataactga cgcatcaatt attatcccta tcttccctca ccatttccgc 4561 actacttgaa ttagtttccg gcatggttga aaggatctca ttaatcctct ttagaatctc 4621 ctcttttttc aattcctcaa gccttttcct tatgaaaccc tctatctctt cattccactt 4681 tatgtcgtac ttttccatct cctcacgtaa ttctttatct atccttaaac tgtataccat 4741 tttcataata tattttacgt ttatggcaaa tataaatctg tcgatataga ttgaagactg 4801 tatcgcagat taaaagagga gaggtgttac aaaatgaaga acaagtttcg cctctttgag 4861 gcgtggtaaa gttttaatct tagttgagag gcactacatg cttcgccttt aatagacttg 4921 agtttgctac cgtaggagaa tgtcccaagc ggaaataatt gaataaatct atgtataagt 4981 ttgtggataa ttattcaaaa gaaaaatgaa ttattgagaa attttgaatt tcctcttgaa 5041 gttaaaggtg gagtaatact caaaggtagc cgggaccatg tagtactgat ccacatgaaa 5101 ccttagatag aataccacaa gggctcggtt ccctatgaag aattatcatc aaagcataaa 5161 acacttgtga aaattaacta cgtactaatc actagtattt ccgggaagtt cttagcgttc 5221 agttttatct aatcctaagt attttattgc attaagatta aacttatact tattttcctc 5281 aaagaactgc ttaatacaat ttacaacttt attcatcgag tgaaatactt tattactcat 5341 gtatgtcttg aagggcttga agaccgcctc tgccatatta agctcaagcg aatagggagg 5401 agtaaatatg ggatgaatgc ccttcctgcg acaaacctca agcgtaccct tagtcttgtg 5461 aggagaataa ttatccataa tcatgtagac cctcccatta ccaaaactta aagcacctca 5521 agaagtactt aagagactca gaattggggc tactgggtat agttatgtaa gaaaatacgt 5581 aagcagaagg ttaaaagtct tcatcaagac tcacctgaaa ccttgaagcg tggagttgtt 5641 tgagatgata tgagtaatgc cttatcaccg acatgggctt gaactcccaa cgcgaattac 5701 tttcatggat cgaaacgtag aggtagacct ccaaggagcg aagagaggga aagtaacctc 5761 cgagctcctc ctcaaaccta gccagggtcg agttgaaact ctccgacgtg ttattagtgt 5821 agaggtagtg tctaacctcc ctggggaagt tgagaaagga acaatacttg tcagcagcgt 5881 caagaagcct cttggctcgg gctggagaaa agggttggac aagttggctg agggacaata 5941 tagccttcct tccctcctcc acgttcctgg aggactttag atccctaact ctaatcatta 6001 gttcctcctt gtccgggagg accctcatga ggttcctaac catgtgtgtt atacagagct 6061 ggtgttgaga ggagggaaag agcgtggaca cgacgcgatc gagtccagag aagtcatcgc 6121 tcacgattac gtcaaccctg ctgactcccc tgcttacgag tccgcccaag aaggacttcc 6181 aaccgtcaag gtcctcccta tccctaactt cgtagtccaa gacgaactta ttcccttcta 6241 agtcaactcc tatggcaatg taaatggctc tctccatgat cgactcgttg attctgacct 6301 ttacgatctt cacattgatg taaagggcta ggagatcgtg aggtagttcg cggttcttgt 6361 attccttgag tttgttggat attctctcgg caacccgatc cattacgatc tcactatacg 6421 gtattccctt ggctgctaac acggccttga cttggcccgg agtcatgctt gatagaacga 6481 gttgctggag gaagtcctcg taatctgggc tggtcctttc tctggaagga tcttgggtct 6541 gaagccaccc tttctggttc tcggtactct gagtcttaat actccgtctc cggttcccag 6601 atatctgaag taggtcccgt tcttgtggtc gtcctcaact tccaagtagg cttctctctc 6661 ttccatcatg acctcttgca agattacctc ctctatctcc cctaggctaa ttccttcttt 6721 gattgccttt cttatctttt ctcttatttc ttccattatc ttcatggtat tactctcctt 6781 tatagtatta ccccttccgg ggttattttt actttttgcc attatttttc acctttgact 6841 accacaacta taactggtag cccctcttcc cacgaaatcg tgtaatgtgc tcttgcccac 6901 tttcctccca acgaactacg ccacaacgac gttcacgttg accatcttta ccgcgtctct 6961 ataggaatag gagtagagta ccatgacgat tagtaacttc aggtaaatca gagtgccttc 7021 tcctagaact ctttctaaat ctagggtgtc taggacgggt ttgatatccg ttaaccattt 7081 ttccctccac ggtatatcct ctcttggggg gagagaatag tacactaagt ttgggatgcg 7141 tcttagtgta cgtgtcatgg tactactctc tcctcctata acttaagtat tactacaatt 7201 taatccaaga taatgctaag aatcaattta ttctcaaaaa ttaaaattca gttttttaca 7261 ttccggacac tctcacgtca tctgctatat ataaaacctc gaattccaca atttaaacct 7321 tcatccaaaa aacctcatag tctccagtga atctatccaa atgaagacca ccaatctgac 7381 ttttatactc atttatagcc ctaatcttga cctctctata ctttctaata tcaaacctaa 7441 cctctctcca attagcttgc atagaacccc atattaagta aaagtaagcc tttggatata 7501 acttctccat cactttacct attttagcgt gatctggatg actatcgaag ggtatcggag 7561 aaaggactac atctttatca tgtaaaaact ctactaacgc tttctcaact tccttttcaa 7621 taaccttaga gtcctcgaaa ctcaagaatg taatctcatc tatacctaaa atcttactag 7681 cccttaatgc ctcttgtctc ctaatctcaa ccaactccat acttcctttt aatttctcgt 7741 ctggagaacc gtatcttccg tcagttacta caacgacact taccttataa cccctttctt 7801 taaaaatctg aacaacccca ccacaacaca aagtctcatc atctggatgg ggtgcaacga 7861 tcaaaacttg catgggatta tctcttcgca aaggctttta tatcttccaa ttctgcttca 7921 gcaaccttat cccaagagga atattcctct ggaattggta ctacttcttc gctcttgaaa 7981 tttgatatta aatcagccaa acccttcacg tcatcctccc ttgccaaatg aactccttta 8041 acgtttccat atatttcctt caaggctaaa gtatcatagg caaatactgg agttccaagt 8101 gctaaagact cgagtataac aagggagaaa ctgtcgtaat gtgatgggta aactgtaaac 8161 atagcctttg ctacagtatt gtaaagttcc tctttttcct taaagcccac atattcaacg 8221 tttacgtcaa gtctcttaat taaggaaagg aaatcatcct tatctctctc atcaacgaat 8281 tcaccaataa catagagctt aacgtctctc cttaattttt tccatatcaa tggaatttca 8341 aaaagtccct tttccggcat gagtcttgta aagtacacag cgtaatcttc cttatccctt 8401 tctctcctaa acttcagtaa atcctcatca aaggcgttgc caggcttcgt aaccctatag 8461 cttaagagct tatctaaact tgaatttatt aagggaacct tgctcacaga aattgcgaag 8521 ttcaagtcac ctctctctat caattccttc cactttactt cttccctctt tgattcttcc 8581 attgcttcct taaacttttt aaccgctcta ccagttattc ccctaaattt tattttgaaa 8641 agtgttgtca tatctcgata aaatggttcc aattgtagtt gaacccctat aggtgctgaa 8701 gttattcttc tagcgagcct aacgttttca gaggaattac tataaacgac tgcaatatca 8761 tatcttttcg ttttaagtcc attcaagaat tcctcaacgc cactactctt ttctaatagt 8821 tcaagaatgt aatctggagt ggaatttaag ctctctagta gggtgattaa atctttccta 8881 catgagtaaa gcctaacgtt tcgtaaagag gggattatat ccacgttaat attccttgat 8941 aatctcttca tgatttcaag gttcctctta tatccacctg tcttctcgtt aagtccaaag 9001 tcaacaaccg ccaaaacgtt cattatctaa tgattaccga tatagccttt taaattatta 9061 tagattattg tctttagcat tcagattgct aggaaaatct tttagtttaa tctgaagata 9121 aaacgataga ataccctaaa cttaagatta taaaatccaa aagaagataa tgtaattatg 9181 tacaagaatc catacggcct cgagattcat ttaattaaag gtgatataac ggaaatggaa 9241 gctgatgcaa tagtcaatgc agctaattct taccttcaac atggtggagg agtagcttat 9301 gcaatagtca aaaagggagg ttacgtaatt cagaaagaga gtgacgaata cgtcgaaaaa 9361 tatggtccgg ttccagttgg agaagttgct gtaactagtg cggggaagtt aaaatctaag 9421 tatgttattc atacagtggg cccaagatat ggaattgagg gaaaggataa gcttgaatcc 9481 gcaattttca aatcattgtt aaaggctgat gaactttcgt taacctcaat agccttacct 9541 gcaatctcaa ctggaattta cggctatcca tatgagatat gcgctagagt tatggcaaat 9601 attctaaaga attacaaagc taagagttta agaaaagtta tagtctgcct ttactctcaa 9661 gatgcatatg acatttttaa gaaagttttt gattcaattt tgaaaagctg actcttaatt 9721 tcctaaatac taattccatt tccagtttca tatcgcttct tgggccaagc tatagatgct 9781 attaagccgt tgtcaacggt ttccaataga gcgtaaagtt tatattattt catcataaac 9841 ttttatacaa tgttaagacc taaggaagta tgccaacgct taggaatatc ctatgcaaca 9901 cttagagaat atgttaagaa gggttacatc aaaccagtag tactagagac tggaaagtgg 9961 aggttcagag aagaggatgt agaaaagtta atgggaatag taagtatgaa gcccaaaccc 10021 cgttaatata gagaatgtag aaaaaataga caaacctagt gaacaacccc gcccttacgg 10081 acgtggcatc tccacctcac gatggagatt tcctgcttct tccaggaaac ctactataca 10141 caccctcaga gaagggtatg tatagcagag gtcccctgtc cacaggctct aagggctgtc 10201 ccgaccccgc atgaagaata tttagagaag cattatagtc acgatctaca gcccaaccac 10261 acttgggaca tacaaacaca cggtcagcca aagccaagtc cttcttaacg tacccacatt 10321 tagcacatgt cttagaagta ttcctcggat ctactttcac taccctccta ccagctcttt 10381 cagccttgta ggagagatag ctcacaaact tagaaaagtt ggagtgaagg atatgctttc 10441 tcaaaacttt actttcacca tcctcgacca tctccttgac atcaagatct tccacataga 10501 tctcatcata ctcttctact aaccacgaag ttactttatg aatataatca ctcatcaagt 10561 tcttcacatg ctcgtgaagc ttagctagtt ttttcctaac cttctcgtag tttctagatc 10621 ccttcttctt tctagataat gatttttgta agatctttat cctcctctcg accttatcaa 10681 aaaccttggg gttctctatt actacaccat cagaggtggt tacgagtttc tccactccta 10741 agtctatccc aactactttc ccagttttct caagaggctt cttttccacc tcaacttgaa 10801 agatagcata ccaaccagtt gaactcttct ttattattac cccttttacc tcgccttcta 10861 acggtctgtg aaaaagcact ttaatctccc ctatctttga gagggtcagc ttgtctccct 10921 caaccttgaa accagattga ttataattga tgatcttcaa gatcttcttg tacctcagtt 10981 tcccaacttt cttccctttc ttcttctgtt cgtgaagagc attgatgttg taccataatt 11041 ggttgttaac catttgaagg gctttagagt aaactagttc cttcccttct attttcagat 11101 ctttcaacat gttttgagtg tctttaggtg ttatcttttt cccttctttc ctcgcgttat 11161 tcaccacgtc tagcaaggca ttgtatactt tagcctcaat ttgcatcact ttgatgagtt 11221 tctcctctac ttctctcgtt gggtaaatct tgtacttgaa tgagagttga atcttatcac 11281 tcttctcctt ggctctccac atattttttc agtacctcca gtgttacttg tccgctcgtt 11341 gctaggaaat aagatggtga ccagaagtgt cctttccaca atttttcctt tacttgtgga 11401 aattttctct gtatttctct agacgtgatt gtcttgattg cgttcacgta cctgggtata 11461 ttcagggttg gttttgcttt gaataacatg tggaagtggt ctttgtctac tcctatgtct 11521 atgacttcaa cttcgaatgt tttgcttatt tcctgaattt gttcctttag gaagttgatt 11581 atttcttcat tatcgaacac ctttctgcgg tacttcacca cttggacata gtggtaataa 11641 agagcgtaaa ctgaatggga tcctctgtcc aatctgtacc gcatagttat atctattttt 11701 taataactat aaaaatattt ctataagggg gctatccatc cctcacggaa ggggactttc 11761 gcccccttaa cccccgtaaa gttaaatcta gtggcaagaa gccatgtgag ggctggaata 11821 aaaccagaac aatatccctt agtaggggaa ttatcactag atgctattaa agaaattcta 11881 aatccaccag aagaagtact aaaagcttgg gaaaaagcat acaattattt gactaaaatt 11941 ctaagagaaa aggaacagaa ataatataat aaaatcgaaa tataatactt ttaagctaat 12001 gcatttttta acacgggatc tgctaaatca tattccctac tttccttctt tacaacataa 12061 cccatcttct caagcttatc caaatacctc ttcaactcag cgtcgtaaac tacccttttc 12121 ttcttatcct ctaaatacct ctttagctca ctccacctac tatgaccctt agcaattgct 12181 tctataacaa taacgtaatc cttcgagaag tgactcaatt cctccattgc aagtttactc 12241 gctatttcca atatctcatc aactatctcc ctctttactt ctccaatctt tacacaccta 12301 taaccaaatt ccgttaacca accaacaata ccgtcaagtt tacttacagc atattccaaa 12361 acgctttcat taggtgaaat gttagcttgt ctaaatccct ccctcaagaa ctccaacgat 12421 ttctcgttac taaacctctt taacctaatc tcctcaacat gcctaccgta aagtggcgat 12481 gaggggtcat ctattttcaa gaagtcatat aataatccaa tctcacttcc cgtgagaata 12541 aacgtaacgt ttttacagta gtcataacaa tgggctaaaa ttgagaggaa tacgttagct 12601 aactttcccc ttaaattctg agcctcatca aaggctataa ttacttttac gctttcgtca 12661 actttatcca ttatttctaa aagggatggt ctattcttag gatcccatga caacgatata 12721 tttataccaa agagggaaat tccctttacg tattttaaga cctcagctac ccttctctcc 12781 ttatttagct gagatagtac atttgaaaat attgtgtaaa gtgatctata ggacgttaaa 12841 ggatatctaa catcgactaa tgcataaggt aacttgctct catttagaaa cactttgaga 12901 agtgacgttt ttccaattct tcttattcca gtgagtagga ttattgagtc atctttggac 12961 gataatagct ttttgagttc ttcttcccta tcgaataagt cctccttagt ttctttaggt 13021 ttaaagtcga agtagattac taacacccta ttagtatact agcaggatgt tattaaaatg 13081 ttttctaaat ctagtaatgt tgaaaccttt atctctctat cttagatcaa gaaaataaac 13141 gctccctaga tagaactcta ctatgttact tctattattt attaaattta ttttgaaaat 13201 agttctctaa gactcttaat gagattatca gcggtaagtt taggtattag agtgtactat 13261 gagaatcatt ttaaaatgtg taatataagt ctttaaaata aaataatgtc ttataaaatt 13321 aagaaaattc attttatata attatttttc actatgatat ataggtattt gaaacatttg 13381 agctaaatat atatatagta actagagtgt taagtatcat aatcttattt atacttcgtc 13441 agactttaaa gggcaaggga acttcattta gtattgacgt ccaaggttca ccacacctct 13501 tcacactgta cgtgaggtaa tttgctcccc tggatatgga gcgtaggaac ctctttgcgt 13561 cccatgttaa ggtctcgaag tccgtgtaga tattcgagta gagccttttc ttgaggactg 13621 cccaaggtcc ctcagctggg ctcttatccg gggagtaaga cggcaggtaa gcacactcca 13681 cgccattttc ctcaaggaat tccctcactt cattaccgtg cattctagcg ttgtccatta 13741 ctatcacggt cttctcgtcc tttattacct tcctcaatat gatatctttt gagttcagcg 13801 atggtttctt gtaggtcgaa taggagaaag atattccctc tttgctaatc gttattccgc 13861 ctactactgc aaacctcttc ctcttaggat taacccttat tcctcctcca acctttaccc 13921 ttgtttatgt aggacacgta agactcgtcg aagatgtgta ccttgtaccc ttcgcttatt 13981 tttttaaaag cttctctcct tgttccttca cccatccttc tacggtcttc tcgtctctct 14041 cgtaagtcct ctttcctttc ttatacttga agcccaactt cttgaggact gggcttaaac 14101 tcctcgggtt gtattttatt ccaaattcct tctcaagtat ataggctatg agcttcaagg 14161 ttcagaagtc gtagtccaag ccgaaatctc ttggactctt ttctaagatt tggacgagct 14221 ttttctcctc cttcagtttt gtggatccct tcctcggctt agcgctcaag tcgtcttttc 14281 tcaaccactt gcacacggta aagacggaga tgtcatactt cttggccacg tcctttattc 14341 tcataccttt ctccacgtct tttacagcgc taattctcct ctcttcctct tgtttcttgt 14401 tgagacttat accgtgcatt ctagattttg gcatacaatt tagtattact catgaaatat 14461 aaatcttgtc ctttaatctg aatgtagtgg ctgtatttct aatgctgagc cttccttcga 14521 ttagggccgt gagtggtaaa cctagtgata cttttctgct caatcccttc atcttcagtg 14581 tttcgactaa ggcttagata ttaagctcat taagttttct taaattcaaa atcaagcgtt 14641 gatttaaaag taggttccac gttaactcag ataaaaattg aagcaatcca cacaggaaaa 14701 agatagagaa tttgtaactt cttaaaatct ctctcctaaa aactccatta aaccccttat 14761 gcctaccatt gcaccggcta tagcaagtat catggatact accaaaacag ataggctttg 14821 aaatgaagct ccaatataat ccaatccgat tgctccgctt aacatcgtaa cgccaactat 14881 tatctttagt attgacctca ttccatttaa cctccatcaa taaagccaac atgccacgta 14941 atgacctgga gaaatttcct ttagcgccgg ttcttgttcc ttgcacttag gcattgcaaa 15001 cggacatctt gggtagaata cgcatccctt atccggccta actatgtcaa ccttaatttt 15061 tatttccttc attttgtctc ttagtgaagg atctattcta ggatatacct caattagccc 15121 ttgtgtatac ggatgtaatg ggtttttaat aatttcattt gaatttccta actctactac 15181 ctttcctaaa tataacactg caatcctatc agatattatt ttagctattg gtaactcgtg 15241 tgttataagc ataaatgaaa aacctttact ttctctagca tcttttatta tcttcaagat 15301 ctctcctttt aatgaagcat ctaacattgt agtaggttcg tctgcaacaa tgtatttagg 15361 gttgacaact atagctctag ctatacttag tctctgtctt tgtccaccag ataactgata 15421 taccctattt tccaatagtt ctagtggaag atcgactaac ctcattgctt cctctatttt 15481 tccatctata tcaatctctt ttttgtactt taatggcatc gctaaaacat cataaactct 15541 cattatagga tctatagatg aataaggatc ttgatatatc atttgaacgt atttgctaat 15601 atctttcaac tttgccttat ttacgttaat ttccctttta tcaactctaa tataaatatc 15661 accagccgta ggtttttgga gacctattgt cactctacct aacgtagttt taccagaacc 15721 gctttcacct acgaccccca taacttcctt ttcttttata cttaacgtta cattatccag 15781 tgctttaact atatacttct tactaaatat tccaccctta gtgaaataca cttttaggtt 15841 ttctacttta actatataat tactaataga gccaacatgc aacctcatca ccatctgaga 15901 atgctttcat tttaggttct tccttaaagc aaatatccct agcaaacgga catcgagtat 15961 tgaatctaca acctactggt ggatttgaga ggtctggcat ggatcctgga atccccttta 16021 ttatatcttt atctaatgtg gcaattgatt caacaagtag tgaagtataa ggatgtctag 16081 gttttttgaa gataacttct gatggtccac tttccataac tttacctgcg tatagcatat 16141 aatccctatc cgaaatctct gaaagtaagg ccagatcatg agttatgaaa attatggaca 16201 agtttaactc tttccttaat tttttcaata ggttaagaat atgttcttga accatcacat 16261 ctaaagccgt tgtgggttcg tccgctatta gaatctctgg atttaaggct agggccattg 16321 caatgaaagc cctttgtttt tgacctccag aaagttcatg ggggtacttt tcggccaatt 16381 gtggatccat gttaaccatt ttgaataact cctcaactct cttatcataa tctccagtcc 16441 aaccatgaat acgtaaaacc tcaattattt gatcccttat cttaaaaaca ggggtaaacc 16501 ctgacataga gccttggaat atcattgcta ttttcttcca tctataattt tttctaaatg 16561 tctcttcgtc cagttttagt atattttcac ctttaaatag tatctctcca ccctcaattt 16621 ttcccggaaa aggaacaagt ctcattatgg tatagcctat cgtactcttt ccagatccgc 16681 tttctccagc gagtccaata atttctccct tatccaaata taagttaaca tcgtcaacag 16741 cctttacaat acctctcttc gtgtaaaagt aaacctttaa atttcttact tctaataaca 16801 tcttacctct cacctaatgt gactctctct attgcgaaac ctattagcac gaaaggtatt 16861 gctacgataa caatcatcgc tccaggaaac acaacccacc accaccatcc gttaacttgt 16921 gcctgataag tttcggcagc atctaaaatt cctccccaag ttactatatt agctggagct 16981 attcctaaaa aggctaacgt ttgggctaaa aggattcctg cggggacacc taaagccata 17041 taagctactg ttattggtat taacctaggc ataaagtgtg taaagaatac tctatatgat 17101 ggtattccaa gtaatttatc agcctcaaca aaactatttg actttattga taaagccatt 17161 gacctagcta ttatagcgta aaatggccaa gacaagaatg ctattaggag ggcttcaatt 17221 tccagattag gttccgttac aaatgagact gcaactaaaa agggaagagc tggcaatgct 17281 aagaatacta aggtaagcca ctgtattgca gaatccttgt ttccacccag ataaccagaa 17341 attcctccga caaaaattcc cacgagtaca gcaactagtg aagttaatgc acctatttct 17401 aacgcattcg gcaatcctaa aagaactcct aaatctaatg gtcttccgaa ataatcagtt 17461 cccatcaaac cataggaatt acccaataag agcaaccttg actttgtaat gttcatagga 17521 gaagatgaca ctatttctat cttaactaca tacctccctt gttcagttgt tgtaaaattg 17581 gattttggag agttaaatag tgctgacgat aatacagtgc tattaactat atttggtgtc 17641 tttccggtaa tcgaagatat ataattcaaa atgtcacctc taatacttgt aaggtcaaat 17701 ggcacattaa atactccatt tggaacgttt atctgtaagg tataaccgtc tggtttactc 17761 caatatatta cttcctcaat aggggtaata ttggttgaga ctatgaaata tacgttatag 17821 gccggtaaga ctttggacca attgaattga tatgttatta ttgctacaaa tatatttttt 17881 gcaggtgaat atagggatat atttattggt gataactcct ccgttgtgaa atacttgttt 17941 gggtaaaaga tagataacca agctggaggt acatgttccg gatactgatt ccaggaggct 18001 ggattattcc aagatgcgta aacttttgca ggaatagata tggctattcc agtaaatata 18061 agtaaaataa ttaaaattat aagacctacc aatccgattt tactagacaa aaaatctcta 18121 agataagagg aaaaacctat atgtctttta ctcaatctta ttcacctacc tttattctag 18181 gatccaataa tccgtaaact aattccccta aaaacaatcc aagtaacaac acaattgtca 18241 aaacgtaggt tatccctaat atcactggta aatcatttaa ggttatggca acataagtta 18301 acaaacccac cccaggccat tcgaaaacaa cctctgtggt taaactacct cctaatgatc 18361 cagctagtgc taaaatagct tgtgtggcaa ttgatgggga ggcagagcgt aagacatgtc 18421 tatacaatat tctggaatct ggtaatcctc tagccttcgc tgtaatcaca aaatcttcct 18481 tcataattga tgtaactaaa cttctaacaa tatatgcgaa tcctccgacg tttacaataa 18541 atatagtaat caatggtaat gacatatgat ataaaacact tattccataa tcaaatggat 18601 tctttggcgg tggaactgag gtcattcctc caggtgggaa aactttaact gcatatgcta 18661 aagcagcaat taggacaaaa cctaaccacc aagtgggaat actagagtgt attacagcta 18721 ttattgcaat taccttctcc cagaatttag attttgcaga gagtaagcca attatagtcc 18781 cagctactat gaatactata gtagcagtag taaataagag aatagtattg ggcaaataat 18841 aagctataat tgaactaacc tctctagaac cagaaggagc ttgtaaaaag taagctgtac 18901 cgaaatcgaa acgcatcaaa ttatacattt ggataaaata tttatcgata attggttggt 18961 taagcccgta agccgcaatt aaagattccc tatacttctc tactgcaatc tgaatttgag 19021 tagagtttag attatgggca tttttaaaca aagtttgaga gaactgtgca acttgaaaat 19081 tgatactctt agctataacc tcctgcaata tgggaaaagt aaaaatataa agaatggtta 19141 aagtggctag aagaactgaa aaataaataa gtaccttttt tatcatatat gtggtaaaac 19201 ccat //