LOCUS NC_017160:7 18764 bp DNA linear BCT 04-SEP-2013 DEFINITION Yersinia pestis D182038 chromosome, complete genome. ACCESSION NC_017160 SOURCE Yersinia pestis D182038 chromosome, complete genome. COMMENT locus start: 905783; locus end: 924546 COMMENT n1_4mer:GRV/n1_4mer:RV = 2.333806; n0_4mer:D = 33.186743; n0_4mer:PS = 18.543492 FEATURES Location/Qualifiers source 1..18764 /organism="Yersinia pestis D182038 chromosome, complete genome." gene complement(-933..17) /gene="iucB" /locus_tag="iucB" /db_xref="904849..905799" CDS complement(-933..17) /gene="iucB" /product="putative siderophore biosynthesis protein IucB" /translation="MGPHAKLIHSGGSFYCEHLGKALTLGLGLDGSAVLHLPGPLPPG WLVQALDQLFIAAPQLTGIALPYAEWRDAPQAMALFALISSDYVAREIFYQLPLWLGA ERNRTAGQMQYDTERHLWYPQRPPRPDGEVYRRFDPNIKRTLSFRLPEVDHDAPQFTR WMNSPRVDAFWEMSGPLDVQAAYLQRQLDSPYCYPLLGCFDDQPFGYFEVYWAAEDRI GRHYRWQPFDRGLHMLVGEENWRGAQYIHSWLRGLTHYLYLDESRTTRVVAEPRIDNQ RLFHHLPAAGYHTLKEFDFPHKRSRLIMNQRADFFREGTR" gene complement(1..1071) /gene="iucA2" /locus_tag="iucA2" /db_xref="905783..906853" CDS complement(1..1071) /gene="iucA2" /product="aerobactin synthetase subunit alpha" /translation="MHPWQADHLLKQDWCQQLVQQNALHDLGEAGERWLPTSSSRSLY SPSNRDMVKFSLSVRLTNSVRTLSVKEAKRGMRLARLAQTPRWQELQARYPTFRVMQE DGWAGLRSADFTLQEESLLVLRDNLLFSQPDSQTNVLVTLTQAAPDGGDSLLASAVRR LAARLNLPLQQAAFCWLDAYCQHVLLPLFSTEADYGLVLLAHQQNILVEMQQDLPVGM LYRDCQGSGFTQSALPWLAEIGEAEAENSFSEQQLLRYFPYYLLVNSSLAVTAALAAA GFDSEENLMVRVRDALSALRTCAKNTLCLDYVLDSPHWHCKGNFFCYLHDHNENTIVD PAVIYFDFVNPLHQGVIHGATR" gene complement(1164..1772) /gene="iucA1" /locus_tag="iucA1" /db_xref="906946..907554" CDS complement(1164..1772) /gene="iucA1" /product="aerobactin synthetase subunit alpha" /translation="MTIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHI PLSSSHAIHIALCHISPTQHHHYLFPAYLHQQGNDRQDDDTPVKLGIEQLVTLLLEKP TVKGELSDDVVARFRQRVLESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAF HPAPKSHQPFNEKQAQRYLPILPPASHYAGLQSINATCAAIA" gene 1912..3135 /gene="" /locus_tag="" /db_xref="907694..908917" CDS 1912..3135 /gene="" /product="hypothetical protein" /translation="MRISSESDARSSGLTSSTHWPLAFCVGLLGIGQNGLLVVLPVLV SRTHLSLSVWAGLLTLGSMLFLVGSAWWGRQSEIRGCKFVVIMALAGYLLSFVLLALA VWGLSAGWLSEMAGLGWLIVARIIYGLTVSGMVPASQTWALQRAGYEQRMAALATISS GLSCGRLLGPLCAALALSIHPIAPLWLMAIAPLIALLVVYRQYNDPPLPPVVHQQNRL RLNMLPYLLCALLLAATVSLMQLGLAPHLSRLFSHSATTVSHHVAILLSIAAGCTLLA QFLVVRPQRFTPPQLLLVAALLMVLGLGLMCVQPLVLFYLGCALASFGAAMATPGYQL MLNDRLSTGKGSGVIATSHTLGYGMSALMVPVVAKFYGESQLVAAAFMMAILLGGISG WLWCQHRTTAHSVGE" gene complement(3425..4258) /gene="" /locus_tag="" /db_xref="909207..910040" CDS complement(3425..4258) /gene="" /product="hypothetical protein" /translation="MTNKIMPKVNREGRRSFLQKSIAVVATGVVTHAFSAPNITLEKD TKPQPGTCILSVEQMAGPYIKSNMPIRRNIAENENGVPLLLKITVIDSNSCRPLEYYY VDIWQCNARGRYSGWSYVDPDKDAPSGEVASINRTDEKSFLRGSQVTDSHGLVRFTSI YPGFYAGRAVHIHFAIKPPKASPQEVDKYSFISQLYFPEEFNSEIEQRAEYSLRKIKR LINSDDEIFNEANGENAVLAVSKINENDINDGVLAEITIAINKDILSKRIDPKDILKI T" gene complement(4635..6011) /gene="" /locus_tag="" /db_xref="910417..911793" CDS complement(4635..6011) /gene="" /product="hypothetical protein" /translation="MLTRRKFLMMSAGAGLLLSVPMLARTGVQPAQAATAITQVFGDG IRLTAVAVEYPTEVSAEGLNPADFHVEGRTVTGVWTSTSTNPADIAPSGRYMIIALSP DDKNATLAEQVQPNSKNNSNKSANGRGGPGNAGDIPAYDTVYRTAQATVLRLPSVHTA SGDTLPASEKALTTQYVENLIVDDFQQLEFYDEKTGKKLKYNLFIPKDYSPDKDYSPD KNYSPDKAWPLVLFMHDAGATSDVTRTTLYQGLGAIAWASPEDQAQRPCFVLAPQYEE IIADDDSKTSDMLDTTIDLINVLSEQYNIDKSRIYATGQSGGCMMTIAMNIKYPDFFA ASFLVAGQWDPALVKPLAQQKLWILVSQDDNKAWPGQNAIIDVLEKEGVQISRAIWDG TWNEEQFRQAFEQIEAEKSPINYVAFREGTVIPEGQSTEGASGHRNTWRIAYTISPIR EWIFRQQR" gene 6573..7316 /gene="yspR" /locus_tag="yspR" /db_xref="912355..913098" CDS 6573..7316 /gene="yspR" /product="quorum-sensing transcriptional regulator" /translation="MHSVFNRSNEVIETLRDYIDRKLTIYDSPKYTYMVINKKNPGDI FIVTSYPNEWAELYTNNNYQNIDPVVLIAFRRFSPFSWDENITVLSELKLSKIFTLSK KYNIVNGFTFVLHDTMNNLAMLSLIMDDSALNGVESRVLNDRDRLQMLLIETHEKMLT LSQRNMNIQERQGKGMPGKAILSPRENEVLYWASMGKTYQEIAIITNITPRTVKYHIG NVVKKLGVINAKQAIGLGVELEIIKPILA" gene complement(7297..7824) /gene="ytbI" /locus_tag="ytbI" /db_xref="913079..913606" CDS complement(7297..7824) /gene="ytbI" /product="N-acylhomoserine lactone synthase YtbI" /translation="MEFDEYDNSDTRYLLGIYQGQLICSVRFIELHLPNMITHTFNAL FDDVALPKRGYIESSRFFVDKTRAKLLFGNHYPISYLFFLSIINYSRHNGYTGIYTIV SRAMLTILKRSGWQVEVIKEAHITEKERIYLLHLPIDRDNQARLLLQVNQRLQDPCSV LSTWPISLPVMPESA" gene 9350..9772 /gene="" /locus_tag="" /db_xref="915132..915554" CDS 9350..9772 /gene="" /product="CAAX amino terminal protease family protein" /translation="LQDMLIPGLALLGLTAIFQFFGQPEPWVESLLQPSTFTQILLVI TICVFAPISEEIIFRGFLLNAGIGFGRRGRLLAVVITSLLFALVHTQYLYPATFVSLF VFSAILCEVRIRTGSLLMPMVLHSANNIASVAWVLTLS" gene 12894..13394 /gene="" /locus_tag="" /db_xref="918676..919176" CDS 12894..13394 /gene="" /product="hypothetical protein" /translation="MSSSSFQNEIPKARINIKLDLHTGGAQKKVELPLKLLVMGDYSN GQEQRPLSEREKLNINKNNFNSVLAEFQPSLKLAVPDTLAGDNTDTAVSLTFNDMKDF EPENVARQIPQLRALLAMRNLLRDLKSNLLDNATFRRELENILKDDALSDELRAELAA LAPKEG" gene 13443..14981 /gene="" /locus_tag="" /db_xref="919225..920763" CDS 13443..14981 /gene="" /product="hypothetical protein" /translation="MSVQENRAQGTATTVLKNSPAAQGVYAALFEKINLSPVSSLAGI EAFQNNDALAEATTDERVTAAVSVFLDLLKQSAKKVEKLDKTLLDGHIAALDDQISRQ LDAVMHHPDFQRVESTWRGVKSLIDQTDFRQNVRIELLDISKDHLVQDFEDAPEISQS GLYAQTYIQEYDTPGGEPIAAAISNYEFDRSPQDIALLRNISKVAAAAHMPFIGSVGP EFFGKENMEDVAAIKDIANYFDRAEYIKWKAFRDSDDSRYIGLTMPRVLGRLPYGPDT VPVRSFNYVEQVKGPDHDRYLWTNASFAFAANMVKSFIKNGWCVQIRGPQAGGAVTNL PIHLYDLGTGNQVKIPSEVMIPETREFEFANLGFIPLSYYKNRDYSCFFSANSAQKPA LYDTADATANSRINARLPYIFLLSRIAHYLKLIQRENIGTTKDRRLLELNNWVRGLVT EMTDPGDDLQASHPLRDAKVTVEDIEDNPGFFRVKLYAVPHFQVEGMDVNLSLVSQMP KAKA" gene 15098..16345 /gene="" /locus_tag="" /db_xref="920880..922127" CDS 15098..16345 /gene="" /product="hypothetical protein" /translation="MAVMHPWGVLQATFELDALAQGRLKAARLHVRFQDGVLVDTECA DVLPPTLTLAASLPAEASDATVMLAIPQLYANGGNCLQPDERGERPVRYRQAWRDVQN QFGDDKKQVAVMYHQLTLRLDTQENGDYQVCPVARLLRDAQGRWTLDPGFIPPMLSLQ ASAWCGEQLELLMVQLRARLQRLMGMRRESNARMADFAVADVSLFWLLNALNSAEPVL GNFQRYPQVHPERLYQELARLAGSLLTFSLEHEVTAIPVYQHEQLTRVFPPLFALLNI LLEASLPSRVVAIELVHEPRINQWRATLRDPRLREGADFYLSVRSSLPAAQLQTQFPQ LCKAGAPDEVGNVVNVALSGIPLRPLSHVPAAIPLRLENQYFSLDLSHPAATQMMETG ACVFYVPGTLGEIQLELFAVLRA" gene 16342..17028 /gene="" /locus_tag="" /db_xref="922124..922810" CDS 16342..17028 /gene="" /product="hypothetical protein" /translation="MNPHLTEHPPVGDIDALLQDTWLQVISLRQGVTCAEGEGQAFWQ RCVADIERVHQALKDAGHSEQSCQHIRYAQCALLDETVKGRGVQDDAYFVWCHSPLQA HFFNTLDAGSQLYERMRAVLREPAPDRAVLTCFHRVLMLGFLGGYASPAASEREQLID QLSVQVPAFSVAPSRGILASAASRNRLGIWLRYWPVRLGLAALMVALLWWGLDHWLSG LLATLLPEPV" gene 17028..18764 /gene="" /locus_tag="" /db_xref="922810..924546" CDS 17028..18764 /gene="" /product="hypothetical protein" /translation="MSRWWQRGLWLWAGLLAVILCLAFLPLSPWGRWLMLAWVVLICM LGGSRAGRQAAGASSDPLFAGLATENGLLPENSRLPVVLVCGDGLASWFGRERSHQSA QGCWLRVDDISTLRQFARQLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQ LMQLRRDSRHPVPLLLSSTVATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAE SRAVQAERLKQAVLFSSQHDWLNAQVLPVLQAPNADVAPLAPQQIIQQQVASLADPVP ASLWQHWLAAHTTLTQVAGWHPPPPAAHDALPLPDFVFSALPLGSGVSSRRRVLRHGV TLLTLAAMVALCSSAWQNRQLLHRVAFDIRQYHSVAMTDYSPKAQAVAVLRRDAGLLD EGYRNGEPLRLGLGLYRGERLRPPLLAAIKSYIPPPPPPPAPPAPKTVRLDSLSLFDV GKFTLNAGSTKMLVTALIDIKAKPGWLIVVAGHTDITGDAQANHILSLKRAEALRDWM LSTSDVSPTCFAVQGYGATRPIADNDTPDGRALNRRVEISLVPQADACQVPDVKTASQ DESDVSTQEMEK" ORIGIN 1 ttagcgtgtg gccccatgga tcaccccctg gtgcagaggg ttaacgaaat cgaagtagat 61 cactgccgga tcaacgatgg tgttttcgtt gtgatcgtgt agatagcaga agaaattacc 121 tttgcagtgc caatgtgggc tatcaagtac gtaatccaga cataaggtgt ttttggcgca 181 agtacgcagg gcgctgagtg cgtcacgcac acgaaccatc aaattttcct cgctgtcgaa 241 acctgcggca gccaaggcag ccgttaccgc gaggctggag ttcaccagca ggtaatacgg 301 gaagtaacgt aataattgct gttcgctaaa gctattttcc gcttcggctt cgccaatttc 361 cgccaaccac ggcagcgcgc tctgggtaaa gccgctccct tggcagtcgc ggtacaacat 421 accgacaggc agatcttgct gcatctccac cagaatattt tgctgatgcg ctaacaacac 481 cagcccgtag tcagcctcgg tgctgaacag tggcaataag acgtgctggc agtaagcatc 541 cagccagcag aaagcggcct gttgcaatgg cagattcaga cgggcagcca aacgacgcac 601 agcactggcc agcaggctgt cccccccatc gggcgcggct tgtgtcaagg tgaccaacac 661 attggtctgg ctatcgggtt ggctgaatag caggttgtca cgtagcacca acagactctc 721 ttcttgaaga gtgaaatcgg ctgaacgcaa accggcccaa ccatcttcct gcatcacacg 781 gaaagtcggg tagcgcgctt gcagctcttg ccagcggggc gtttgagcca aacgtgccaa 841 gcgcataccg cgtttggcct cttttaccga cagggttcgt actgagttgg tcaggcgcac 901 actgagtgag aacttgacca tgtcgcggtt tgacgggctg tacagtgaac gtgaagagct 961 ggtgggtagc cagcgttcac ccgcttcgcc cagatcatgc aacgcgtttt gttgtactaa 1021 ttgctggcac cagtcttgtt tcaataggtg atcggcttgc caggggtgca tggggagcag 1081 ccaaacgtca tcggtaaaat gcgcgagtaa ttgtggggcg ctttcgctgg caaagcgttg 1141 cagccggtgt tgtagcgtta gctttaggct atcgccgcac aggtagcgtt tatcgactgc 1201 aaaccagcgt agtgggaagc gggaggcaaa atcgggagat aacgctgggc ctgtttttca 1261 ttaaaaggtt gatgggattt cggtgccggg tgaaaggcat ggccggccag taatccttgt 1321 tctgcctggg caaaattaag tggtttatcg cgtaatgacg gccaatccag acgaatatta 1381 atcgcttgct gagtattatc atgactttct agcacccgtt gacggaaacg agcaaccaca 1441 tcatcagaca gctcaccttt taccgttggc ttctccaaca gaagcgtcac caactgttcg 1501 atcccgagtt ttaccggggt gtcatcatcc tgcctatcat taccctgctg atgcaggtag 1561 gcagggaaca gatagtgatg atgctgtgtt ggggagatat ggcataaggc aatgtggata 1621 gcgtgtgaag aagaaagagg aatgtggagt tgtgggtacg gttggtggcc cgctgccgga 1681 acgatctgcc agtcctgggt ttcacgaatc agcgcgttga ggaaacattg agcagccaca 1741 tcggttgcta aggtttctac tgggatagtc atgatgtcat gtcgcttatt aatccattga 1801 gaacgattct tatatcaata gtggttatca ttatcaattg gaatatgata caatttttca 1861 ataaatctcc ttcaaaaaac cacactttta ttaacggtta atttactttt aatgcgcata 1921 tcctcagagt ctgacgctcg ctcaagcggg cttacatcgt ctacccattg gcctttagcg 1981 ttctgcgttg ggttactggg catcgggcaa aacggtttat tagtggtgtt accggtattg 2041 gtaagccgca ctcatctgtc attgtcggtg tgggcgggtc tattgacact tggctcaatg 2101 ctatttttag tgggatcggc atggtggggc cggcaatcgg agatccgtgg ctgcaaattt 2161 gttgtcatca tggcactggc aggttacttg cttagctttg ttttattggc gctggcggtg 2221 tgggggttgt cagcagggtg gttatcggaa atggccggtc tgggctggct aatcgtggct 2281 cgtattattt atggcctgac cgtctctggt atggtgcccg ctagccagac ctgggcacta 2341 cagcgtgccg gttatgagca acggatggcg gcgctggcga ccatcagttc ggggctgagc 2401 tgtggccgtc tgctcggccc attgtgtgcc gccctcgcgc tctcaataca cccgatagcc 2461 cccctgtggc tgatggcaat tgcaccactg atcgcactgc tggtggtgta tcgccaatac 2521 aatgacccgc cgttaccccc agtggtgcat caacaaaacc gtttacgcct caatatgttg 2581 ccttatttac tgtgcgcgtt gttgctagcg gcaaccgtca gcctgatgca acttggcctg 2641 gcacctcact taagtcgatt gtttagccat tcggccacca cggtgagcca ccacgtggcc 2701 attttgctta gcatagccgc gggttgtacg ttgctggcac agtttctggt ggttcgtcca 2761 caacgtttta cgccacctca gttgctgcta gtggcagcct tgctcatggt gcttggcttg 2821 gggctgatgt gtgttcaacc gctggtatta ttctatctag gttgtgcgct ggcttctttc 2881 ggcgccgcga tggcgacacc gggttaccaa ctgatgttga acgaccggtt atctactggc 2941 aaaggctccg gcgtgatcgc taccagccat acattgggct atggcatgag tgcattgatg 3001 gtgccggtag tcgcaaaatt ttatggtgag tcacagttgg tagccgcggc gttcatgatg 3061 gccattttgt tggggggaat cagtggctgg ctgtggtgcc agcatcgaac aaccgcccat 3121 tctgtgggag agtaactggc gctgcccggc cagcatcggt gacaaacggt tggcgtgggt 3181 tggtccgtta gcggtgatgg tcgcgccgcc cgatgatgag caggtgttgg ctactcacct 3241 tatgggctgc gctgcaatgg gtgcaaatgc atcgtgatat ccgccatcct atttccttga 3301 gctgtaaata atactttgta gttatttttc gccactgtaa aaggggacgg tgttcaatgg 3361 gatagctttc ataaaaaact aatttattga ttttagatac taataaaatt gaatgtgttt 3421 ggctctatgt gatctttaaa atatccttag ggtcaattct tttagacaag atatctttat 3481 ttattgctat cgttatttcc gccaaaacac catcattaat gtcattttca ttgattttac 3541 tcacggcaag gactgcattt tcaccatttg cttcgttaaa tatttcatca tcactattta 3601 ttaacctttt gatttttcta agcgaatatt cagcccgttg ttctatttcg ctattgaact 3661 cttctgggaa gtaaagctga ctaataaatg agtatttatc gacctcctga ggagatgctt 3721 ttggtggctt aatggcaaaa tgaatatgaa cagcacgccc ggcataaaac ccagggtaga 3781 tactggtaaa cctgacgagc ccatgactat cagttacctg tgagcccctt aaaaaacttt 3841 tctcatcagt tctgttgata ctcgcaactt ctccacttgg tgcgtcttta tcagggtcaa 3901 cataactcca tcccgaataa cgcccccgag cattacattg ccatatatca acgtaataat 3961 attctaatgg gcggcatgaa tttgaatcga taactgttat tttaaggagt aaaggcaccc 4021 cgttttcatt ttctgctatg ttccttctta ttggcatatt acttttaata tatgggccag 4081 ccatttgttc aacagataaa atacatgttc caggttgagg tttggtatct ttctctaatg 4141 taatgttcgg cgcagagaat gcatgggtca ctacaccggt agcaacgaca gcaatcgatt 4201 tttgtaagaa tgatctgcgc ccctcgcgat taacttttgg cattattttg tttgtcatgt 4261 cataaacctc tcttggttta tatggttaaa ttaacgttca cgtgtcgtaa atatctaatg 4321 catcccttcg gttgccttca aaaatagcca ttcaaaatca atgtaattaa atgaaaatat 4381 attttttatt gtgtttttat tgtctttttt tataaaaaaa atgataaatt tcatgcttaa 4441 ttattagcat gaaatttatc atagggaagg gacaattttg acaaaatgtt ctattgccta 4501 aaagtagatt cgctgattat gcaatagctt gagagtggct ttaatgctca ataaatcgtc 4561 gttttgtcga agggtgaggg ctgtcgaacg atcaaagaga agcgtgcggc gttgggtaag 4621 ccctcgttaa tcaactagcg ctgttgcctg aaaatccatt cgcgtatggg ggagatggta 4681 taggcaattc gccaggtatt gcgatgcccg ctggcacctt cggtggattg cccctcagga 4741 atcacggtgc cttcacgaaa tgccacatag ttaatcgggc ttttttctgc ctctatttgt 4801 tcaaaagcct gacgaaattg ctcttcattc catgttccgt cccatattgc acggctgatt 4861 tggacaccct ctttttccag aacatcaatg atggcattct gacctggcca ggctttgtta 4921 tcatcctgag aaaccagaat ccagagtttt tgctgggcaa gaggtttcac caacgcggga 4981 tcccactgac ccgcaaccaa aaaagaggcc gcgaagaaat ccggatactt gatgttcatc 5041 gctatcgtca tcatgcatcc acccgactgc cctgtggcat agatacggct cttatcaatg 5101 ttgtactgct ctgaaagtac attgataaga tcaatggtgg tgtccagcat gtcagatgtt 5161 tttgagtcat catcggcaat gatttcttca tactgaggtg caagaacaaa gcaggggcgc 5221 tgtgcctgat cttctgggct tgcccaagca atagcgccta agccttgata cagggtggtg 5281 cgtgtaacat cgctggtggc gccagcatca tgcatgaata acaccagcgg ccaagcctta 5341 tcagggctat agtttttatc agggctatag tctttatcag ggctatagtc tttggggatg 5401 aaaaggttgt atttcagctt tttacctgtt ttttcatcat aaaactcaag ctgctgaaaa 5461 tcatcaacga tcaagttttc cacatattgg gttgtcaacg ctttctcgct agcgggaagc 5521 gtatcaccac tggcggtatg aactgacgga aggcgcagta ccgtggcttg agctgtccgg 5581 taaaccgtat cataggcagg aatatcgcct gcattaccgg ggccgcctct tccattggca 5641 gatttgttgc tgttgttttt actatttggc tgcacctgtt cggccagcgt tgcattcttg 5701 tcatcaggtg atagcgctat aatcatatag cgtcctgagg gcgctatatc tgccggatta 5761 gtagaagtgc tggtccatac accggttact gttcgccctt caacatgaaa gtcggcgggg 5821 tttagccctt cagcgctgac ttctgtcgga tattcgaccg caacagcggt tagccggatc 5881 ccgtcaccaa aaacttgcgt aatggcggtg gcagcttgtg caggctgaac accggttcga 5941 gccaacatgg gtacagagag taaaagacct gctccggcac tcatcatcaa aaatttccgg 6001 cgtgttagca ttatttgtct cctttaactc agcacgttgt atctacttta gtttcatttt 6061 aacaaggctg taagaattta tgcgattcgt ggcaaatgga tgactcatat taccgcacca 6121 aaattacaat atttgggggt aaaaattatt tatttacgat gagagtctgg ttcacgctcg 6181 atattatctt cagttgctaa aaaaacaaac tgactgagtt tagaaaactg attaatgata 6241 cagaccttag ataaggaatt gacatggggc gagggacaat taatcacaat gaaaatattt 6301 gcaagacatt tagcaaaaat tgaggggagc tagacattat attaaatgct acagaagttc 6361 tacttgcaga aacaggtgca cttctgtagc attttccttt attatttttg gtttttccct 6421 ggtattgact agacttttgt tgtcacctga ctcaagtagc taggtttttt catcaactta 6481 ctctatccat tatacgggaa cgggtatggg gcggtagttg tactaaggtg caatttccta 6541 ttgcacctta gtacagtaaa tggagaaagg gaatgcattc tgttttcaat aggagtaacg 6601 aggtaataga aacactgcgt gattatatcg acagaaaact taccatctac gacagtccaa 6661 aatataccta tatggtgatc aataaaaaga atccaggcga tattttcatt gtcactagct 6721 acccaaatga atgggctgaa ctctatacaa ataataacta ccagaatata gatcctgttg 6781 tcctgatcgc tttcaggcgg ttctctccgt tctcttggga tgaaaatatt actgtccttt 6841 ctgaactgaa attatcaaaa atcttcactc tctctaagaa atataacatt gttaatggtt 6901 tcacttttgt tctgcacgat acgatgaata atttggcaat gttgtcactc attatggatg 6961 atagcgctct gaatggagta gaaagtagag tgttgaatga tagggacagg ctacaaatgc 7021 tcctgataga aacccatgaa aagatgctta cattgagtca aagaaatatg aatatccagg 7081 aacgccaggg gaaaggtatg cccggtaaag ccattctatc cccgcgagaa aatgaagtgc 7141 tctactgggc cagcatggga aaaacctatc aagagattgc cataatcaca aatatcaccc 7201 ccagaacagt aaaatatcac ataggaaatg tggtaaaaaa gttgggtgta attaacgcaa 7261 aacaggcaat cgggcttggt gttgaactgg aaattattaa gccgattctg gcataacggg 7321 caacgatata ggccatgtac ttaatactga acatggatcc tgcaaacgct gattaacctg 7381 taaaagcagc cgtgcttgat tgtcccgatc tatcgggaga tgcagtaagt atatcctttc 7441 tttttcggta atatgtgctt ctttaatcac ctcaacctgc cagcctgatc gtttaaggat 7501 ggtcaacatt gctcggctga cgatagtata aatacctgtg tagccattat gtcgggagta 7561 attaataatc gataaaaaga ataagtagct tatggggtaa tggttaccaa aaagcaactt 7621 ggcacgggtt ttatcaacga agaaacggct cgattctata tagcccctct taggtaatgc 7681 cacgtcatcg aagagtgcat tgaaggtatg agtgatcata ttaggcaggt gaagttctat 7741 aaaacgcaca ctgcagatta gttgaccttg gtaaatacca aggagatagc gtgtatccga 7801 attatcatat tcatcaaact ccatgccgtt gctgcaattc acctcccagt taagacgatc 7861 cttaaacgtc tttttcctta atttatacag gtcctcagac cgtatatcgg tcaactcgtc 7921 gtatctgaca tcgaaaattt ctaacattat ctttcctgat atttaatact gccagtgtgc 7981 atatgttaaa ttgaattgta ttgtatcatc acaaaataag ttgtcacatt agggaataat 8041 tggattgcta atagttctgg gagtccgtta acgggtaaac aagtacgtct acccaacctc 8101 agaatctaca ttaactttac cataacttat gccgcataat ttaatctatg tgaagtggca 8161 cgctaaattt ttccatctgt gttgactata aggtgatatt gggtaattcc cccgaaaaaa 8221 cgtgtgttta taagtataat tctctcgtag catgaatcga ggcgatttgg atgaaaagat 8281 cacgttctag cgagagccaa attatggcta ttctggggca gatatgcttg ttgatgaatt 8341 gtgtcgtgac gatcgtttct ataaacagtt atcgctataa atgttactcc cgcttggcgg 8401 tatggccgca tctatagtga agtgtctcaa agcgctggag gacgaaaact gttggctgaa 8461 caaatgtatg ccaaagagaa gagtgcttaa gatctgaaat tattcggttg agatctcaaa 8521 aattgtttgg aactaaaacg gatctactta tattcacatc tgagatgatc tcaatttgaa 8581 agaataccgt taagaataaa cagcgtaaag aaattgtaga cgcgggattt tttaatattt 8641 tatatcgata attataattt ttataaataa aataaaatta aactccaatt caaatggata 8701 atcattccac aaaaaatcat ttaacttagt ttattagtct gatttttatg gtcatttgga 8761 ttttttgttc taattaattg attttgtaat gaataatgtg tcaatttctg ctttcgtcgc 8821 cgtccgctaa ggctaatctt tagcatattg ccatattaaa tgcattcgag tattcttcgc 8881 gcaatttgtg gctggaatta tttatcatct actttatagg catacaacca atgcatcatg 8941 acttctgggt gaaattactc aaaacagcgg gatgcataaa gcgtcagccg ctgcacgtat 9001 taccaagaag aatgcgtgtt atcgcttggg ttagtatcct acttcagtta agacttccct 9061 cagttttatc atttaaaccc gctattacca aatgcacaga tataattaac ggaatattac 9121 gatgaatgga aagattgacc gggttactca tgccctgact tgtgtttctg tttggatagg 9181 atggtttgca ctttcatttt ccctgctgct gtttcctggc tatgtgggaa tatatcgctc 9241 aggtatggcg actcctctgc tgtacatcgt tttctggctc ccctttacgc tactggcgtg 9301 gaagcattat cagaagtcgt ttggactgat gccgttggga agaataacct tgcaggatat 9361 gctgattccg ggccttgctt tgctgggatt aaccgctatt tttcagtttt tcggccagcc 9421 ggaaccctgg gtggaaagcc tattacagcc atcaactttc actcaaattt tgctggtgat 9481 aaccatttgc gtgtttgctc cgatttcgga ggagattatc tttcgtgggt tcttactgaa 9541 tgcgggaatt ggttttggtc gcagagggcg gttgctggcg gtagtgatca cctcgctgtt 9601 gttcgctctg gtacacactc aatatctcta tccggcgacg tttgtttcgc tattcgtttt 9661 ttctgcgatc ctgtgtgagg tcagaatcag aactggtagc ctactgatgc cgatggtgct 9721 tcattctgcg aacaatatag cctccgtagc ttgggtgctg acgttgagtt aaggcggttt 9781 ttgggcgccc ctgtaggtag atgttggctt tgtgcgccaa ccaactttga acttaccggg 9841 caagcgcctt actctgaggc caacgatgac cgactgttta gtttatacac actgagctaa 9901 tccgtggtca gtttttgttg accattaccg tggtgagtgc tgtaccaggt aactttaata 9961 ttaaaattac gacagtgaat tattggtgct ttcccaactg ggaaaagtaa tataaaagac 10021 atgcagatgt tctttttgac aaagaagtca ttaaaaatac attaggtggg agtgttcttt 10081 ctcaggtcct tatctttaat gggtgaggtt ttttattgct actataactg tatttatatc 10141 tacaccttta atctataagc gttagatggt tttttagagt gttaattttt tgggggcggc 10201 atgttaaaaa atgtcataaa ttatgatgaa taaatttttt aaaataatat cgataaattt 10261 attggcaatt tctcttggtg gttgtgggat gatgcttaat cctctgctta tgaagcaggc 10321 tgaagttgaa cccaacaact tacctgatgg taagttagga caaccctatt atgctaaact 10381 tagaataacg gggggaggcg gtgctattgc ttcttttaag ggagaatcga tgccagttgg 10441 atcagggttg gtattaacat cggataatcc agagcgacca ccgggtagag atgaactggt 10501 tataaaaggc attcctgtga tatctggtga tattacgttt agagtcagcg gtgccttgtt 10561 tagtagtgca gataaaggtt attttggtaa agaatataaa ttaaaaatag ccgaataata 10621 ttaatttcgg taatgactcc aattggttga atttgatgta caatgcgatt ttttgaggtt 10681 tgctcatggc ttgcattaac gttcattgtc cccgttgtga ttctgctttg gtttatcgac 10741 atggtcagaa ccctaagggc caaagccgtt tccgctgccg tgagtgccgc tctgtattcc 10801 aactgaccta cacttatcag gccagaaagc ccgaagttaa agggcagatc gttgatatag 10861 cctttagcgg cacaggtgtg tgggatacgg caagaacgct aaaaatcggt atcaataccg 10921 ttatccgcac tttaaaaaac tcttgctgaa gcgaataacg tcctcgccag tcgctcatgt 10981 agacgtggcg ctcatctgtg aactcgatga gcagtggagt tttgtcggca acaaggccca 11041 tcagtagaaa ctacggagtc atcaatagta gtcaatgcga tgcttctgga ggaaagtata 11101 tcgaaagagg agttagataa atatggtgtt tggaatcaaa aataaattta tgttaaaact 11161 aattattttt attatctcag taattattat gattggtagt tacagttttg tctcggcctt 11221 gtacataagt atgttcgata ttacttctca cagaagcgtt gggatgatat ttatatcttt 11281 ttatttttta ttgattgcct cacctgtttt acttataact ttattcacaa gattcagggt 11341 tagttttgcg attttacttt gtggagtatg ttatttattc tttgaatggt actcgttgca 11401 ccctctcaga gttatattga tgggggcaag tgtagtaaat ggatatattt tcattttgac 11461 gactagaaaa atatggagcg tgtattcaat atagtgttca tcagataaac tactcgtttt 11521 tatctgatgg attcttatgg ctaatgttga tgtaaaatat ctgatttttc agcacaggct 11581 cggtgaaaaa aacatgggca gcggagccgt gggcattaac gttatcgctg tcaggcatgt 11641 tgccgaagct ttcaacttga atatgaatac cgcgtcagcc aatagggtat gaagatacaa 11701 attgttgagc atagaaacac agtaacctgt ccccacattg tgttttacaa catgaatact 11761 gggaatgtca ccacatcgtg ataaggaaat aaaaatgaag agaaaaaaat agtaggaagg 11821 aagacgttcc ttttgcgctg gttctgaaag ccttcagata gatagatacg atggccgcat 11881 gcgagtgaac gcctcaaaaa ctggggtcat tgggacaagt cccaggcggc aagccactgt 11941 gttgcagccc tacgccaaca tccaataagt gtgcattctt cgtaatttta attgcttccc 12001 atactcactc ggccactcaa tcctgccacg gtttatcatc accttttgta tctactcaaa 12061 tttacctaat ttcggaacgg tctgggggag gcgtttgtct attgaaatga cgtctgataa 12121 atgcaaaata tgacgcatta aaagacactg atattcgttt ttcttgaaaa caattagatt 12181 gagattattt actgtattga cctacataat cgaacccgat aatttattac ctctctacat 12241 tattagccgt gttaatgctc gggataatga actcagcatt ggcatcaatg acttaaactc 12301 tcgtattagt caatgatctg atttatctaa caattatgtt tatgttagta atgctttact 12361 gatttactaa agtaataagt gttctatttg tctaatttcc aacgaggcaa tattatcgtt 12421 ttagatctca tttatagaaa aatatttaca ggtaatttgt aggtatattc ctacaaatca 12481 cttcccaaat tcctcatttg gttttaatcc tgtttaatta cccctttaat aacagtgtgt 12541 tattacctgc cacgtaagaa acttcttaca aatcatatgg atgctatgta ttttgaaatt 12601 gaatttggtt gcattctgtt acatttaacg catttgcgtt aatcgaataa tgtttctaga 12661 ctgcgccatc cggtatttta ttgctctgct catgcgtgtg agaaatacct gtcagagact 12721 gtttcatgcc atccaatgaa tggatagggt tatcgataaa tattatttct ttactttata 12781 cacactgagc taatccgtgg gtggtgaatg ctgtgccagg taacgtagat tatttttatt 12841 cattctctct gtggtggatt tccttaattc ccttccctta ataaggaacg ttgatgtcct 12901 cttcaagctt ccaaaatgag atacctaaag cacgcattaa catcaaatta gacctgcata 12961 ctggcggggc gcaaaagaaa gtcgaactgc ctttgaagtt gttggtgatg ggcgattaca 13021 gcaacggtca ggagcagcgc ccgctgtctg aacgtgaaaa actcaatatc aataaaaata 13081 attttaacag tgtgctggct gaattccaac cgagcctgaa actcgctgta ccggacacgc 13141 tggccgggga taacaccgat acagccgtct ccctgacctt caacgacatg aaagatttcg 13201 agccagaaaa cgtggcccgt caaattccgc aactgcgtgc cttgctggcc atgcgcaacc 13261 tgctgcgaga ccttaaatcc aatctgctgg acaacgccac cttccgccgt gagctggaaa 13321 atatcctcaa agacgatgcc ttgagcgatg aactgcgcgc tgaactggcg gccctggcgc 13381 caaaagaggg ttaatcccgg gattggctgc ttgtcattag aaagaagaaa aggaacatgc 13441 tgatgtctgt acaggaaaac cgtgcgcagg gtactgcgac gaccgtatta aagaatagcc 13501 ctgcggcaca aggggtttac gccgccttgt ttgaaaaaat caacctgagc ccggtctcct 13561 cactggccgg tatcgaggcg ttccagaaca acgatgcgct ggcggaagcc accaccgatg 13621 agcgcgttac cgccgccgtc agtgtctttt tagacctgct gaagcagtcg gcgaagaaag 13681 tagaaaaact ggataaaacc ctgctggacg gccatattgc cgcactggat gaccaaatca 13741 gccgccagtt ggacgcggta atgcaccacc ccgatttcca gcgggtggaa tcgacctggc 13801 gtggtgtgaa gtcgctgatc gatcagaccg atttccgcca gaacgtgcgc atcgagctgc 13861 tggatatcag taaagatcat ctggtgcagg attttgaaga tgccccggaa atctcacaaa 13921 gcggtttata cgcccagacc tatattcagg aatacgacac ccccggcggc gagccgattg 13981 ccgcggctat ctccaactac gagttcgacc gtagcccgca agatatcgcg ttattgcgca 14041 atatctccaa ggtcgcggcg gcagcccata tgccgtttat cggttccgtt ggccccgagt 14101 tctttggtaa agagaacatg gaagacgtgg cagccatcaa agatatcgcc aactactttg 14161 accgtgctga atacatcaag tggaaagcct tccgcgactc ggatgattcc cgctatatcg 14221 gcctgaccat gccgcgcgtg ctggggcgtt tgccttacgg cccggacacg gtgccggtac 14281 gcagcttcaa ctacgttgag caggtgaaag ggccggatca tgatcgctac ttgtggacca 14341 atgcctcatt tgcctttgct gctaacatgg tgaaaagctt cattaaaaat ggctggtgtg 14401 tgcagatccg gggcccgcag gccggtggtg cggtcaccaa cttaccgatc cacctgtacg 14461 atctgggtac cggtaatcag gtcaaaattc cgtcagaggt gatgatcccg gaaacccgcg 14521 agttcgagtt tgccaatctg ggctttatcc cgctgtcgta ctacaaaaac cgcgattact 14581 cgtgcttctt ctcggccaac tcggcgcaga aaccggcgct gtatgacacc gcggatgcca 14641 cggccaacag ccgcatcaac gcccgtttgc cgtatatctt cctgctgtcg cgcattgccc 14701 attatctgaa actgatccag cgcgagaaca tcggcaccac caaagatcgc cgtctgctgg 14761 agctgaacaa ctgggtgcgc gggctggtga cggaaatgac tgatccgggt gatgatttgc 14821 aggcgtccca tcccctgcgt gatgccaaag tgacggtcga agatatcgaa gacaaccccg 14881 gcttcttccg cgtcaagctg tatgcggtgc cgcatttcca ggtggaaggg atggacgtca 14941 atctgtcatt ggtttcccaa atgccaaagg ctaaggcata aacggcgaca cgatgaaaat 15001 tgaacgccct ctgtgggctc gcgggatcct ggtgtctccg caacaatttc aacaacaggc 15061 ttcctgggag gcatggacca atgaatgcat tgcgcaaatg gccgtgatgc atccctgggg 15121 cgtgcttcag gccacttttg aattggatgc attggcacag ggccgcctga aagcggcgcg 15181 tttgcatgtg cgttttcagg acggtgtgct ggtggatacc gagtgtgctg atgtgctgcc 15241 gcccacgctg acgctggcag ccagtctgcc cgccgaggcc agcgacgcca cggtgatgct 15301 ggcgatacca caactgtatg ccaatggcgg taactgcctg cagccggatg agcggggcga 15361 acgcccggta cgctatcgtc aggcctggcg cgatgtccaa aatcagttcg gcgatgacaa 15421 aaagcaggtc gcggtgatgt accaccaact gaccctgcgg ctggacactc aggaaaacgg 15481 cgattatcag gtctgcccgg tggcgcgttt gctgcgggat gcgcaaggtc gctggacact 15541 ggatccgggc tttattccgc cgatgctgag cctgcaggcc agtgcctggt gtggcgaaca 15601 gcttgagtta ttgatggtgc aactgcgggc gcgtttgcag cgtctgatgg ggatgcgccg 15661 ggagagcaat gcacggatgg ccgattttgc tgttgcggat gtgtcgctgt tctggctgct 15721 caatgccctt aacagtgccg aaccggtatt ggggaatttt cagcgctatc cgcaggttca 15781 tccagagcgc ctgtatcagg aactggccag gctggcgggc agcctgctga cgttctccct 15841 tgagcacgaa gtgacggcga tcccggttta tcagcatgaa caactgaccc gcgtctttcc 15901 cccgttgttt gccctgctga atattctgct ggaagccagc ctcccttcac gggtagtggc 15961 gattgagctg gttcatgaac cgcgtatcaa tcagtggcgc gcgaccctgc gtgaccctcg 16021 tctgcgcgaa ggggccgatt tctacctgtc ggtccgttcc tcgttgcccg cggcccaatt 16081 gcagactcag ttcccgcagt tgtgtaaagc cggtgcgccg gatgaggtcg gtaacgtggt 16141 gaatgttgcg ctgagtggga tcccactgcg cccgctgagc catgtcccag ccgccatccc 16201 cttgcggctg gaaaaccagt acttctccct tgatctcagc caccctgcgg cgacgcagat 16261 gatggagacg ggggcctgtg tgttctatgt acccggtacg ctgggtgaga tccaactgga 16321 gctgtttgcg gtgctacgcg catgaatcct cacctaaccg aacacccccc agtcggggat 16381 attgacgccc tgttgcagga cacctggcta caggtgatca gcctgcgtca aggggtaacc 16441 tgtgccgagg gcgaagggca ggcattctgg cagcgctgtg tggcggacat tgaacgtgtc 16501 catcaggcgc tgaaagacgc cggtcacagc gagcagagtt gccagcacat ccgatacgcc 16561 caatgtgcac tgctggatga gaccgtgaaa gggcgcggtg tacaggatga tgcctacttc 16621 gtgtggtgcc attcgccctt acaggcgcat tttttcaata ccctggatgc cggtagccag 16681 ctttacgagc ggatgcgcgc cgtgttgcgt gagcctgcgc cggatcgcgc ggtactgacc 16741 tgttttcacc gggtattgat gttgggcttc ctcggcgggt acgcctcccc ggcggcttct 16801 gaacgggagc aactgatcga tcaactgagc gtgcaggtac cggcgttcag tgtcgcgcca 16861 tcacgtggga tcctggcaag cgccgcctcc cgcaaccggt tggggatctg gttgcgttac 16921 tggccggtac ggctcgggct ggctgcgctg atggtcgcgc tgttgtggtg gggccttgat 16981 cactggctgt ccggtctgtt agccacctta ctgccggagc cggtgtaatg agtcggtggt 17041 ggcaacgtgg gttgtggctc tgggcgggtt tgctggcggt catcttgtgt ctggcatttc 17101 tgccgctctc cccgtggggg cgctggctga tgctggcatg ggtggtgctg atttgcatgc 17161 tgggcgggtc gcgggcaggg cggcaagcgg ccggtgcatc ctctgatccg ctgttcgccg 17221 ggttggcaac tgaaaacggt cttctgcctg aaaacagtcg cttaccggtg gtgttggtat 17281 gtggtgatgg tctggcgtca tggtttggtc gcgaacggtc acaccagagt gcacagggct 17341 gctggctgcg ggtggatgat atcagcaccc tgcggcagtt tgcccgacaa ctgctgtggc 17401 aacggccgga atgggccgct cagttggcgg tgatgatggt cgtgaacccg cagcaacgcc 17461 gcgatgagcg cctgctggcc gccgatctgc aagagctgcg ctggcaactg atgcaactgc 17521 gccgcgatag ccgccatcct gttcccttgc tcctgagcag cacggtggcc acctcggttg 17581 cccgtgatac ggtctggctg tcacagcagc agacaccgcc gctgacactc tggtcaaccg 17641 tctcgacgcc gggctctctg gccgactggc agcgtgcgga aagccgtgcc gtacaggccg 17701 aacgactgaa acaggcggtg ctgttcagca gccagcatga ctggctgaac gcacaggtgc 17761 tgccggtatt gcaggcaccc aatgcggatg ttgcccccct tgccccgcaa cagattattc 17821 aacagcaggt tgccagtctg gccgatccgg tgcctgcctc gctgtggcag cactggctgg 17881 cggcgcatac cacgctgaca caggtggcgg gttggcatcc accgccgccc gccgcccatg 17941 acgccttacc gctgccggat tttgtctttt cagcgcttcc tcttggtagc ggggtgtcgt 18001 cacgccgtcg ggtactgcgc catggtgtca ccttactgac gttggcggcg atggtggcgt 18061 tgtgcagcag cgcctggcag aaccggcaac tgttgcaccg ggtggccttt gatatccgtc 18121 agtaccacag cgtggcgatg acggattatt ccccgaaagc gcaggcggtg gcggtattac 18181 gccgtgatgc ggggctgctt gatgaagggt accgcaacgg tgaaccgctg cgtctgggcc 18241 tggggttata tcggggggag cggctgcgcc cgccgctgtt ggcggcgatc aaaagctaca 18301 tcccgccccc tccgccccct cccgcgccac cggcgccgaa aaccgtgcgc ctcgacagcc 18361 tgtcactgtt cgatgtgggt aaattcacgc tgaatgcggg gtccaccaaa atgctggtca 18421 cggcgctgat cgacatcaaa gccaaacccg gctggctgat cgtggtggcc gggcataccg 18481 acatcaccgg cgatgcgcag gccaaccaca ttctgtcgct taagcgcgcc gaagcattac 18541 gcgactggat gctgtcaacc agcgacgtct cgccgacctg ctttgcggtg caaggttacg 18601 gggccacacg ccctatcgcc gacaacgata ctcccgacgg tcgggcgctc aaccgccggg 18661 tcgaaatcag tctggtacca caggctgatg cctgtcaggt gccggatgta aaaacagcgt 18721 cacaggatga aagtgacgta tcaacgcaag aaatggagaa gtaa //