LOCUS NC_015732:22 18865 bp DNA linear BCT 11-OCT-2011 DEFINITION Spirochaeta caldaria DSM 7334 chromosome, complete genome. ACCESSION NC_015732 SOURCE Spirochaeta caldaria DSM 7334 chromosome, complete genome. COMMENT locus start: 3145634; locus end: 3164498 FEATURES Location/Qualifiers source 1..18865 /organism="Spirochaeta caldaria DSM 7334 chromosome, complete genome." gene 0..377 /gene="" /locus_tag="" /db_xref="3145634..3146011" CDS 0..377 /gene="" /product="response regulator receiver protein" /translation="MSTILIIDDDSTIQDVAEAILKNQGHTVLKALDTLQAERYLSSS CIDLILLDIVLPGQGGLEYLMDIRNRHPNIAVIVMSGKVRTDLLPVKKLAQQFGAVCI LSKPFTAPELIESVTAALKSSCN" gene complement(441..1223) /gene="" /locus_tag="" /db_xref="3146075..3146857" CDS complement(441..1223) /gene="" /product="tRNA/rRNA methyltransferase SpoU" /translation="MAELDLAWFAELKDRELRKERIIIAEGRLVAERTAAFCDALGIL CVPAALEDAEAISRGTIPIQVLSEAEISKLAGYPFHRGLLFAARRPELQPLSEAGTLV ASGQRLVVLPQITDPENLGAIIRTAAALGWDGILLGPRSADPYSRRVLRCSMAAVFAL PIYTFHGAGELELLASTGWELWAAMLSPDSCSPESLRQVKKLALMLGNERFGLSQEML NRSCAQVTIPQRRFEVDAVDSLNVAAAAAILLWEGRPGLISG" gene complement(1216..1953) /gene="" /locus_tag="" /db_xref="3146850..3147587" CDS complement(1216..1953) /gene="" /product="hypothetical protein" /translation="MKHWYPAVVCFLLFISCASNPEIGGMCQSSYGNFIIHHVDERVT VLEDLVRALEAAESAGAEFFNVSVPVTHVYIYTDHQQFVTKKYGLIGRLLNLEWYIGD NIGEKVLLLSPDHPTRVHDYDSILGAVGHEYIHTVIYRLYPHCPLWLNEGVALYLTNG SRGKAIHQSMEFPPEKILTSGNPLYFANHNGYSFADSFIQYVLEIFGKEALFRLLERG DYEKALGLDRSQVYQGWKAWFMGRTNG" gene complement(1981..3390) /gene="" /locus_tag="" /db_xref="3147615..3149024" CDS complement(1981..3390) /gene="" /product="Tryptophan synthase beta chain" /translation="MSIHDKKPYGPIRVVLSEDEMPRQWYNLAADFKTPMLPPLGPDG KPVTPDMLSAIFPAPLIEQEVSQERWIDIPEPVLEILSRWRPSPLHRAVALERALGTP ARIYFKNESVSPAGSHKPNTAVAQAYYNKISGVKKLTTETGAGQWGSALAFSCALMGM ECKIYMVKVSFEQKPFRKLMMQTWGGTCIPSPSPYTEAGRSVLAKDPNCPGSLAIAIS EAVEEAVSDKTGSTKYALGSVLNHVMLHQTIIGQEVKAQLAKIGERTPDSVIACVGGG SNFAGLAFPFVKDKIEGANIDIIAVEPASCPTLTKGVFAYDLGDMSGMTPLLPMHTLG HEFIAPTIHAGGLRYHGMAPLVSKAVLDGLVEPRSVHQLECYDAAVTFARTEGIIAAP ESSHAIAMAIREAKQAKEEGKEKVIVFGLSGHGLMDLAGYEKYFAGQLQDYEFSGEDL ENSLKCIQSFPKPPAAVAR" gene complement(3467..4606) /gene="" /locus_tag="" /db_xref="3149101..3150240" CDS complement(3467..4606) /gene="" /product="glycosyl transferase family 2" /translation="MLVIFTIFFFIIFVGLHLVLMAGLYLEYRRDLSARNNVLTGTIS VSIIIPVHNEANRISALLKSLLKQDYPLIELLFIDDRSTDETASIIHEFSKQFNLEGH LCRLLQLTENPGPNYKQFGLIKGFEAAAGELVLLTDADCELPTTWVSGMVKRMSNLNT GLVIGPVFKKTPQASFLYKTQAFDHVVRYGYLAASTAIGAPGGGFGNNMAVRKSVLDA AGGYGAVPFSVTEDAALISFINQKTPCKIRASLGPDIHVLTETEPTWKQFFIQGLRWT KGGIFSPDRSTRLSFNMLMLMISLGMVALPLLVLESLLWPLPVAVWVAMSMNTIAAIV ISGEHLKDLRPIDFLIQIFIIPMLNVVLTLMVLLRLPVYWKGKKV" gene 4695..4768 /gene="" /locus_tag="" /db_xref="3150329..3150402" CDS 4695..4768 /gene="" /product="tRNA-Ala" /translation="GELAQLARAIGSQSIGQGFESPIL" gene complement(4940..6943) /gene="" /locus_tag="" /db_xref="3150574..3152577" CDS complement(4940..6943) /gene="" /product="AAA ATPase central domain-containing protein" /translation="MEGFTYWDYRYTELLLQCWNTQEHGDDLYDLIHNQCDLLKVLIP NISAEEKDSVNRDKAVNEIKEYVSMHMQRTNPKLTELADRFNLQAHHIKIVEFLYIYG SMNAFTAYFEKQSAACQLVILTTWVHISKNELVAELRLHSPMGKLGLLEFERFALFDL RHINIRVGLNKYVHNYLEDINNRPLSSFLLHVLEPPYFALETFDLPEATILSAKAALK RHGPAFLLFYGEPGTGKSELSKALSLSCNLIPYSLMTDDVDGSRPLSNLYLSAKLLDS KKEVLIIDEADTLLNSEDVLSAQGTPSTFKAIVNQFLDNATIKIIFITNQTNRIPASV LRRMHIIIGFKPASIQYRKQMWETNNNVTNLFSSTDIDKLAKDFKANPSRIRQVYEIC SLLKEDCESQERILEVAKDMLSRSQEMLMKDNQKINNKIEEIDVGLLHLSIDPYVLLD RIKKWYDTFSRTQQGLNILFYGLPGTGKSALAIHIATELQLQPIIKRASDLFSPYVGV TEDRIRDAFKEAENNVLILDEADSFILNREKNERSWERSQTNEFLNQMDDFKGLFIAT TNFIKALDGASFRRFPYKVEFYPPTPDQRLTLARRYFSHITFDTEACFRIHNLEGLVP GDFSSVAKRLAFVDSPTPQEIISELELELKSRSHLQHTIGFKV" gene complement(7001..8764) /gene="" /locus_tag="" /db_xref="3152635..3154398" CDS complement(7001..8764) /gene="" /product="hypothetical protein" /translation="MKYEPLSIEEILSNNYYIIPRYQRNYAWEKTEIAQLIRDINEYS QNGESKNYYLGSLVCFKREDGVFELVDGQQRFTTLVLINLVLKNWNYENKDNDILFVV KTSNLKFDSRKRVQNYIDRLYNTDKNDFINVLCDFNDQDISIVAIKDAIEIIQEELRS IENVTDFSDTFYNKVYLFHVDIPKDTDLNHYFEIMNNRGEQLEKHEIVKALLMGKLAT DDEMDHQKFAMIWEACSDMSNYVNVKMEDADNETNDHVSYTLKEIIEHNNDKDTINKE KYTQDKYKSIINFSNFLLQVLKLRYEQVALDDKKLLQQFKEIDPEPKIFINDLLKYRK MFDTYVIKQDITNADETKQNWGIRKLDNADSNTIIKTFEDDEEIVKIELMLYYSDSSN TYNDWLHKIMKWLSKNENPTAEKYRQELWEIAKSKFNRVCLSYPNITIYNLYFIDFLL WKLYKEKKEGAPDTIINKIENIKNKFNNFKFRQLTSREHLLSQEHARRNDPENISLYN GIGNLCLISASQNSKGNKENPIDKKKLFQDDNSSLKRLIMFESFENNTWGKEQIRKHQ EEIKKLVDIYLSQNTPISSHP" gene complement(8754..10118) /gene="" /locus_tag="" /db_xref="3154388..3155752" gene complement(10225..10629) /gene="" /locus_tag="" /db_xref="3155859..3156263" CDS complement(10225..10629) /gene="" /product="hypothetical protein" /translation="VTGIGTLIGYIDYVQEETVAVLSTYMITQDENYLVSYEIKNGTE KRELLGRYERKGYRFLAATEEYYLICNDFWYVSLDRCSNGVAREHISEPCIGIKEVVI NYKKKDKKALIGFQHGRFVYYYDELFQLVTIE" gene 10682..11668 /gene="" /locus_tag="" /db_xref="3156316..3157302" CDS 10682..11668 /gene="" /product="hypothetical protein" /translation="MYKQLSEILTAARLISRTSGATIKELENHLHLSRRSVYRLLDTL EELGYPLYDEFHGKERVIFLNEHRDNLRWWIPYPQVELNSEDIILLEYLFKEAAKTSA VANEIRRLKEKLGPLLAEGGYTLAGDLHQSGILPAPSLSKKFDASKHQLLKTILQGIQ ERAVCIVSYQAISSATVKTFRIHPLILMEKYGGLYLFVFVPYYGNIRILAVERIKNFE LTEEEFAMPAHFTPEPWLTDPFGIILNKTFTARIWFSPEQAPYIQELNWPEGSNLETQ NDGSLILTVQTAADYELKRWVLSFGSSACLLEPEHLRREIQKELQDMENLYQ" gene 11738..12376 /gene="" /locus_tag="" /db_xref="3157372..3158010" CDS 11738..12376 /gene="" /product="hypothetical protein" /translation="MKNKTFFLLILAMTLLLSSCIEITQHIRLENNTIINNTRIVIQK ALLTMAQSYGNDSDLSSLEFNDETIYQISEQIPKENFVSIKKVNNELENGLEITVRYP RTKRPTVQNDDVAPIFYPYLKNKTLVVEFNNMSSTNIDENNQMVSAILSGFKYRLFID SSVLSSPKKATLYTKDEETTYTMPLINYSNFTLVEISMAYLLSGQSLRLVIE" gene complement(12396..13190) /gene="" /locus_tag="" /db_xref="3158030..3158824" CDS complement(12396..13190) /gene="" /product="phosphonate-transporting ATPase" /translation="MISLQDCIVVFNANTPDERRALNSIRLMIGQGDFVTVIGSNGAG KSTLLNLIAGSVRPSSGSIVIDGIDRTGEPEYLRARSIGRVFQDPLAGTAAEMTVEDN LAVAARKGRKPLTIAMTRARKVEFRDRLAELGIGLENRMKENVSRLSGGQRQALTLLM AVIARPSILLLDEHTAALDPANAEKVLELTQRFAQEYELSVIMVTHDMARAITIGNRL VMMDKGEIIMDVSGTEKSSLTVDALVHRFREIRKQEFAGDRALLVE" gene complement(13187..14113) /gene="" /locus_tag="" /db_xref="3158821..3159747" CDS complement(13187..14113) /gene="" /product="ABC transporter integral membrane subunit" /translation="MISAILVEGLIYGILAMGVFITFRVLDFPDLTVEGSFPLGAAVA ASCLTAGIPFPVAALIAITAGALAGTMTSLIHTGLKVPPLLAGIVVMTGLYSINLRVM GGRSNIQLISNRPLIQFSATWFPALPPEVASALFFLLLAIIIMVLLDLFFHTEFGLTM GALGDNVKVVIASGSNPTTFKAAGVALANALVAFAGALASQHHGFADVNLGAGVVALG LASVMIGELVLRTNRIGLQLFRVVLGAIIFKAILFGARFYGYIAGITPNDLRLLTALM IVLSLVLGQWKSALQDQRAQQASLQRKAEEVL" gene complement(14138..15130) /gene="" /locus_tag="" /db_xref="3159772..3160764" CDS complement(14138..15130) /gene="" /product="ABC transporter substrate binding protein" /translation="MKKSVKMIGYTLIGLGLVALAACGAGSVKKVSDEPKIGVAKIVA HPALDALEKGIVEEITAAFPKAKIDLQNANGEPATASQIAQKFKVDKVNVAVGIATPT AMALANVLTDIPVIYSAVTDPVAAGLVASYDKGGEHITGTSDLPPLEGQLDTLIALAP NIKRIGHIYNAGEANSVTTAAKAEAYVKSKGLEFVTATVTNSAEVSQALTSLVGRVDG IYLSTDNTVFSAISTVADICLKAKLPLVTADPSSAETVPVLAAVGFNYYEMGKATGRI VVEVLKGKKTADIPTYFAKDPKEQALVINLDVAKKIGVTVPQAYIDRASLVIGK" gene complement(15223..16674) /gene="" /locus_tag="" /db_xref="3160857..3162308" CDS complement(15223..16674) /gene="" /product="Malate dehydrogenase" /translation="MNVDISLKDLDSLFPGDFTEEQKARAKTLFLKNLSLEAHQFYGG KMQTLPRCGIFGFNWFNVWYTPGVSKISTTIRDDNDSSFALSSRGNMVAVVSDSTRVL GDGDCTPPGGLGVMEGKAMLMKYLGGVDAVPLCVDSRDASGKNNPDKIIEFVKMVQHS FGAINLEDISQPNCFKVLDELRETCDIPVWHDDAQGTACVTLAGLINALKLVNKKLSE VRIVLLGAGASNTTIARLLMTDGADPAKIIMFDSQGSLHTGRKDIETDTRNYRKWELC QKTNPQGIKDMDTAIKGADVLIALSTPGPDTVKREWVRSMAEKAIVFACANPVPEIWP YAAKEEGAYIVATGRGDFPNQVNNSVCFPGILKGALLVRSRKITDGMAIRCAHSIADF AERRGISPENIIATMEETEVFAVEAADVAMQAIAEDVARVPMTWDEVYQQAKADIAAS RSLVADMQRLGHIKEPPQEMLEAALQSAIEAVK" gene 16878..17111 /gene="" /locus_tag="" /db_xref="3162512..3162745" CDS 16878..17111 /gene="" /product="CopG-like DNA-binding protein" /translation="MPNVTMSIDEELLKSARKIAIEKNTTVSDMVRSYLTNLVKSETI RREYVADELERLFNKSTAHSQGIRLTRDALHDR" gene 17101..17523 /gene="" /locus_tag="" /db_xref="3162735..3163157" CDS 17101..17523 /gene="" /product="PilT protein domain-containing protein" /translation="MTDKIIFLDTNILVYANDNAYPEKQKIARNYIREVIITGNGYIS TQVLAEFWVTVTQKLPTCLSQDLAREQISLFSNFHIIPVEYPTILEAIRLQERYQISF WDAQIIASALQVNATVLLTEDLQHGLSINSITIQNPFL" gene complement(17518..18864) /gene="" /locus_tag="" /db_xref="3163152..3164498" CDS complement(17518..18864) /gene="" /product="PTS system Galactitol-specific IIC component" /translation="MQVLSDVISWIFSFKVYLLLPILFFIIALFSKMPLGKALLQSLK VGIGFAGVFLIFDAFLGMMHPAVQAMVEARNLQFPIIDAGWPPLAAITWSSWIAPLII LLVLFLNVLMLLLRWTTVFYIDIWNYWHFALIGSMLMAVGIPLPLALAGSLFAALLVF KMSEMTTPYVQNVAGITGVSISPLTVAGFAPWAIAMDAVIEKIPGLRWLHWNPSRSEG PWAVLGEPMIVGLFMGLLFGYLAAYDVKQILETAVKIAAIMFLLPHCGSLIGDATGSI SRAASERMAPLFGRRTIAIAMDTGFLMKIPSVIVTGMLLMPISLALAFVLPGNKVLPA GDLPNLMSIFSVVVLISGGNVIRAILIALPVIIAFLYSATALGPLITELAQKAGTIPG VSEGSSLVVSSFTDGGNPLRFWIFELFRGNLIALVLIVPVAVLLWYASKKASRAQL" ORIGIN 1 atgagtacca tactaattat agacgatgac agcaccattc aggatgtggc tgaagcaatc 61 cttaaaaacc aggggcatac cgtcttaaaa gctctcgaca ccctgcaagc tgaacgttat 121 ttatcctcat catgtataga tcttattctg cttgatattg tgttacccgg tcaaggcggc 181 ctggaatacc tcatggatat caggaatcgg catccaaaca ttgctgttat tgttatgtct 241 ggtaaggtgc gaacggacct cttaccggta aaaaagctgg cccagcaatt tggcgccgtc 301 tgtattcttt caaaaccctt tacagcacca gaattgattg aatctgtaac agctgctctg 361 aaaagcagct gtaattaact gcggcctggg ttgcggctac tgccatacac taggagcctg 421 tcggacaagt ccgacaggct cctagccaga aataagccct ggccggcctt cccagaggag 481 tattgccgcg gcagcagcta cattaaggga gtccacagca tccacttcaa aacgcctctg 541 tggaatcgta acctgtgcac aagaccggtt caacatttcc tgagacaagc caaaccgctc 601 attacccaac atgagagcaa gttttttcac ctgacggagg gactcggggc tacaggagtc 661 tggactgagc atggccgccc agagttccca tcccgtgctt gcgaggagtt ccaattcacc 721 ggcaccatga aaggtataga tgggtaatgc aaacaccgca gccatagaac agcgaagcac 781 ccgccggcta tacggatcgg cagaacgagg gcccagcagg attccatccc atccaagagc 841 cgcagcggtt ctgataatgg cccccagatt ttccgggtct gtaatttgtg gcaaaacaac 901 aagtcgctgc cctgaagcaa ccagcgtccc cgcttcggac agaggttgta gctcaggccg 961 ccgggccgca aacagtaagc cccgatgaaa gggatagccc gcaagcttgc tgatttctgc 1021 ttcgctcaga acctgtatgg gaattgttcc tcggctgatg gcctctgcat cttccaaagc 1081 ggcgggcaca caaagtattc ccagggcatc acaaaaggct gcggtccgtt cagccacgag 1141 ccgaccttca gcaataataa tcctttcctt acggagttct cggtctttaa gctcggcaaa 1201 ccaagccagg tccaactcag ccattggtac gacccataaa ccaggctttc cagccctgat 1261 acacctggga ccgatcaagg cccagagctt tttcataatc accccgttcc agcaaacgga 1321 acagagcttc tttgccgaat atttccagca catattgaat aaaagaatcg gcaaagctat 1381 agccattatg gttggcaaaa tacagcgggt ttccagatgt cagtattttt tccggaggaa 1441 attccataga ttgatgaatt gctttgccgc gactgccgtt ggtgagatac agggccaccc 1501 cttcgttaag ccagaggggg caatggggat ataaccgata gatgaccgtg tgaatatact 1561 catggccaac tgcaccaaga atactgtcat aatcatgcac cctggttgga tggtctggcg 1621 agagaagcaa taccttttcg cctatattat ccccaatgta ccattcaaga ttcagaagcc 1681 ggccgatgag gccatacttc tttgtcacaa actgctgatg gtctgtatag atatatacat 1741 gggtaacagg aacggaaaca ttaaaaaact cagcccccgc gctttctgca gcttccagag 1801 ctctgaccag atcttccaga actgtcaccc tttcatcaac atgatgaatg ataaaattgc 1861 cataagaact ttgacacatt ccccctattt cgggattgct tgcacaggag ataaagagca 1921 gaaaacaaac aacagcaggg taccagtgtt tcataccctg ctgttatagc agaaaggact 1981 tttaccgtgc aacggcagcg ggtggctttg gaaagctctg aatacatttc agagaatttt 2041 ccaaatcttc accggagaat tcataatcct gcaactgtcc agcaaagtac ttttcataac 2101 ccgccaagtc cataagcccg tgaccggaaa gaccgaaaac aataaccttt tcctttcctt 2161 cttccttggc ctgttttgct tcccggatcg ccatggcgat ggcgtggctc gattcgggag 2221 ctgcgataat gccttcggtt cgggcgaagg tgaccgccgc atcatagcat tcaagttgat 2281 gaaccgatct gggttctact aggccgtcga ggaccgcttt ggataccagc ggagccatac 2341 catggtaccg gaggccccct gcatgaatcg tgggggcaat aaactcgtgg cccagggtat 2401 gcatgggaag gagcggtgtc atcccggaca tgtctcccag gtcataggca aaaacaccct 2461 tggtaagggt cggacatgaa gcgggttcta ccgcgataat atcgatatta gccccttcga 2521 tcttatcctt tacaaagggg aaagcaaggc ctgcaaaatt ggatccgcca cccacacagg 2581 caatgaccga atcgggggtc cgttcgccaa tcttcgctaa ctgggccttt acttcctgac 2641 caataatggt ctgatgcagc atgacatgat tcaggaccga cccaagggca tacttggttg 2701 aacccgtctt gtcagacacc gcttcttcca ccgcttcact gatggcgatg gcaagactac 2761 cgggacaatt ggggtccttt gcaagaacag accggccagc ctcagtatag gggctcggac 2821 tgggaataca ggtgccgccc caggtctgca tcatcaattt acggaagggc ttctgctcaa 2881 agcttacctt aaccatgtaa attttacatt ccatacccat gagggcacag gagaaggcca 2941 gggcacttcc ccattggcca gcccctgttt cagttgttag ttttttaact cccgatattt 3001 tattgtaata ggcctgggcg accgccgtgt ttggcttgtg acttcctgcg ggggatacgc 3061 tttcattttt aaaataaatc ctggctgggg tacctaaggc ccgctcaagg gctaccgccc 3121 gatgcaaagg cgacggccgc cagcgggaca aaatctccag caccggttca ggtatatcaa 3181 tccagcgctc ctgggacact tcctgctcaa taaggggggc tggaaaaata gcggaaagca 3241 tatccggtgt tacgggcttt ccatcgggcc ccaggggagg cagcatgggg gttttgaaat 3301 ccgccgccag attgtaccac tggcggggca tttcatcttc cgaaagcacc acccggattg 3361 gtccataggg ttttttatcg tggatagaca taattggctc cttttatgtt tctatatata 3421 gatacattat gtataacata ggaactaacc tttgacaagt ctttttttta aacttttttg 3481 cccttccaat agacaggcaa gcggagtaga accatcaggg tcaacacaac attcaacata 3541 ggaataatga aaatctgtat aaggaaatct ataggacgca ggtcttttaa atgttctcct 3601 gaaatgacaa tcgctgcaat ggtattcatc gacatagcaa cccacacggc caccggcagg 3661 ggccaaagca ggctttccaa aacaagtaac ggaagggcta ccattccgag acttatcatc 3721 aacataagca tgttaaaaga aagtctggtt gacctatcgg gactaaaaat acctcctttt 3781 gtccagcgga gaccctgaat aaaaaattgt ttccatgtcg gttcagtttc agtgagcaca 3841 tgaatatcag gacccaggct agccctgatt ttacagggag ttttctggtt gataaaggaa 3901 atcagcgctg catcttcggt aacactgaaa gggactgcac cataaccacc agcagcatct 3961 aatacagact tccttaccgc catattattt ccaaagccgc caccaggagc tccaatagct 4021 gtggaagctg ctaaatatcc ataccgaacc acatgatcga acgcctgggt tttataaaga 4081 aaggacgctt gaggtgtttt tttaaaaacc gggccaataa caaggcctgt attcagatta 4141 gacatacgct taaccattcc actaacccag gttgttggca gttcacaatc cgcatcggtc 4201 agcaatacca gttctccagc agctgcttca aaccccttga tcaaaccaaa ctgtttataa 4261 ttgggccccg gattttcagt aagctgtagt aatcgacaca aatgaccttc gagattaaat 4321 tgtttactaa attcatgaat tatagaagct gtttcatcgg tcgatcggtc atctataaaa 4381 agcagctcta taagaggata atcctgcttt aaaagcgatt ttagaagcgc agaaatccgg 4441 tttgcttcgt tgtgaaccgg aataattata gaaactgata tggttccagt tagtacgttg 4501 ttgcgcgcac tcaggtctct gcgatattcc agatagagac ctgccataag caccaaatga 4561 agaccaacaa aaatgatgaa aaaaaagata gtaaaaatca ccagcatatt acaaaccata 4621 caatgaaaca tcatattgtc aagaactaag cggtcttgat ttttacgtta tgttgatggt 4681 aatatagatc ttgacgggga attagctcag ttggctagag cgattggttc gcaatcaata 4741 ggtcaggggt tcgaatcccc tattctccaa tcatgaaaaa ccggcctttg ggccggtttt 4801 ttactttaga atgaataggg gattcgaacc gagtgagcac cgcgcggaag cgtgggaagg 4861 tgcccatgga ggggcaccgc cagcgaacga ggcggcccgg aaacctgagg cacgatgccg 4921 aaggttgtag ggcgaatccc ctatacttta aaaccaatag tatgctgtag atgactgcgg 4981 cttttgagtt ctagttccag ttcgctgatt atttcttggg gtgtcggact atctacgaac 5041 gcaagccttt ttgcaacgct tgaaaagtcg ccagggacca ggccttccaa gttgtggata 5101 cgaaaacaag cttctgtatc aaaggttata tgggaaaaat agcggcgggc caaagtaaga 5161 cgctgatctg gagttggcgg gtagaattca accttatagg ggaaacggcg gaagcttgca 5221 ccatccaggg ccttaataaa gttagttgtg gcaataaaca ggcccttaaa atcatccatc 5281 tgattaagaa attcattggt ctgactgcgt tcccaactcc tttcattttt ttcgcggtta 5341 aggataaaag aatcggcttc atctaaaatc aggacattgt tttcagcttc cttaaaggca 5401 tcacggatcc gatcttccgt aacaccaaca taaggactaa aaagatcgct tgccctttta 5461 atgataggct gaagttgtaa ctcagtggca atatgaatag ccaaggctga ttttcccgta 5521 ccgggtaatc cataaaaaag gatatttaat ccttgctggg ttcgagaaaa tgtatcatac 5581 cattttttaa tccgatctaa aaggacatag ggatctattg aaagatgtaa aagccccaca 5641 tcaatttctt caattttatt atttatcttc tgattgtctt tcataagcat ttcctgactg 5701 cggctgagca tatccttggc cacctctaga atccgttcct ggctttcgca gtcttccttg 5761 agtagggaac aaatttcata gacctgacgt atccgagatg ggtttgcctt aaaatccttg 5821 gcaagtttat ctatatccgt agaagaaaag aggttcgtaa cattattgtt tgtttcccac 5881 atttgttttc tatattgaat acttgcgggt ttaaaaccaa tgataatgtg cattcggcgc 5941 aggactgaag ctggaattct gttagtttga ttagtgatga atattatttt tattgttgca 6001 ttatctaaaa attgattaac aatcgctttg aacgtcgaag gtgtaccctg ggcagaaagc 6061 acgtcttcgc tgtttaaaag agtatccgct tcatcaataa tgagaacctc tttttttgag 6121 tccaataatt ttgctgaaag atagagattt gaaagaggac ggctaccatc cacatcgtcg 6181 gtcatcaaac tataggggat tagattacac gaaagagaga gggctttgct caactctgat 6241 tttccagtcc ctggctcacc ataaaaaagt aaaaaagcag gaccatggcg ctttaacgcc 6301 gctttagcag aaagtatggt tgcctcaggc agatcaaagg tttctaaggc aaaatagggc 6361 ggctctagaa catgcaataa aaatgatgaa aggggccgat tgtttatatc ttccaggtaa 6421 ttatgcacat atttatttaa gccaactctg atatttatgt gccttaaatc aaataatgca 6481 aacctttcaa attccaataa acctaacttt cccataggac tatgcagtct aagttctgct 6541 acaagctcat ttttcgatat gtggacccaa gtagtaagta taaccaattg gcaggccgca 6601 gattgttttt caaaatatgc agtaaaagca ttcatactac cataaatgta caggaactct 6661 actattttga tgtgatgagc ctgtaaatta aaacggtctg ccagctctgt cagcttaggg 6721 tttgtccgtt gcatatgcat cgatacatat tctttgattt cgttaactgc cttatcccgg 6781 tttacactgt ctttttcctc cgccgatata tttggaatga gcacttttaa taaatcacac 6841 tgattgtgaa taagatcata caaatcatca ccatgttcct gtgtattcca gcattgcagt 6901 aaaagctcag tataacgata atcccagtag gtaaagccct ccatactaaa acctccagga 6961 ttattgtaaa ttacaggagt gccaaatccg gtcacaggtg gctatggatg agaagaaata 7021 ggcgtatttt gtgataaata aatatcaact aactttttta tttcttcttg atgttttcta 7081 atttgctctt taccccatgt attgttttca aaactttcaa acattatgag gcgcttcaaa 7141 cttgaattat catcctggaa taattttttc ttatcgattg ggttttcctt attacctttc 7201 gaattttgag atgcggaaat taaacataaa tttcctattc cattataaag agaaatattc 7261 tcaggatcat ttcgtcgggc atgttcttgc gataaaagat gctctctaga agttaattgc 7321 ctgaatttaa aattattaaa tttatttttt atgttttcta ttttatttat aatagtatct 7381 ggagcgcctt ctttcttttc cttataaagt ttccaaagta aaaaatctat aaaatagaga 7441 ttatatatag ttatattagg gtagcttaaa caaactctat taaacttact ttttgctatt 7501 tcccacaatt cttgtctata cttttctgcg gtaggattct cgtttttgct aagccatttc 7561 attattttat gtaaccaatc attatacgtg ttactagaat cagaataata caacatcagt 7621 tctattttaa ctatctcttc atcatcttca aaggttttga ttatcgtatt agaatcggca 7681 ttatctaatt ttctaatacc ccaattttgt tttgtttcat ctgcatttgt tatatcttgt 7741 ttgattacat aggtatcaaa catctttcga tatttcagta aatcattaat aaatatttta 7801 ggttctggat cgatttcttt aaattgttgt aaaagttttt tatcatcaag tgctacttgt 7861 tcatacctta actttaacac ttgtagtaaa aaattagaga aatttattat agacttgtat 7921 ttatcttgag tatatttttc tttattaata gtatctttat cattattatg ttcaataatt 7981 tcctttaatg tataagagac gtgatcattc gtttcattat ctgcatcttc catttttaca 8041 tttacataat tggacatatc tgaacaagct tcccatatca tagcaaattt ttggtgatcc 8101 atttcatcat cagtagcgag ctttcccatc aaaagtgctt ttacaatttc gtgtttctct 8161 agctgttcac ctcgattgtt cattatttca aaataatgat ttaaatctgt atcttttggt 8221 atatctacat ggaataaata aactttatta taaaatgtat ctgaaaaatc tgtaacattt 8281 tctatagatc ttaattcttc ttggataatt tctatcgcat ctttgatcgc aactatactt 8341 atatcttggt cattaaaatc acataataca tttataaaat cgtttttatc agtattgtac 8401 aaacgatcta tatagttttg aacccttttt cgagaatcga acttaaggtt cgatgtttta 8461 acaacaaata gtatatcatt atctttattc tcataattcc aattttttaa gactagattt 8521 atcaatacaa gcgttgtaaa cctttgctgg ccatcaacca actcaaaaac accatcttca 8581 cgtttaaaac aaactagaga acctagataa taatttttac tttctccatt ttgcgaatat 8641 tcattgatat ccctaattaa ctgagctatt tcagtcttct cccaagcgta attgcgttga 8701 tatcgtggga ttatataata attatttgat aatatttctt ctatgcttaa gggctcatat 8761 ttcattttct attcctccat atataaattt acatattttt tcagttccaa taacactact 8821 ttcatttttc tttttataat ttttaaattg ataatcatgt aaatcggctg ggcttagact 8881 attgcttatt ctattaaaaa cttttattgc ttcactatgt ataattgttt ctacagtaat 8941 tctattcttc tcgcaacgca atgtataaac taatttataa aatgcttgat aaatattttc 9001 aaaatcatca ttaataaagc caaatttatc aatgaatgct atcataatat tctcaaatag 9061 atttctaact ttttcatctc cgctcctcga ccagccacta tatccaaaac aatattcttc 9121 ataaaattca acaaattgtt ttgattttgc ttttatttca tcttctttat ttaaatcaaa 9181 tatctgctca cgaagactaa tataataatc aacatattca aaaaatcttt taccgttaat 9241 tatggggctt gtaatttaga atgggaaagt ttgcgcaaca tttaaattta ttaatatttt 9301 attttttttt aaattttcaa ataatccatc taacattcgt attccggttt cataaggata 9361 tatttggggt tgtttaagtg aaacaccttt aaattcgtct atttcatctt ttgtaaaatt 9421 atatttatat tcatttttac tccatttacg aattctaaag agatgattgc cgagtattgg 9481 ttttaaagat ccgttactta tcgatttttc ccatcgttca acacattttt ctcgttcttc 9541 ttcactatcg gactccattt cacgtaaatg aaatgctttt aataaatcat acggttcaag 9601 tggtttacct cttgcatttt gagcatcaaa tagttgaaat gcttcttcct gatcaagaac 9661 tgtaaataga acaacttcac atttgttcat gatttttctt ctaaaatctt ttttatcttt 9721 atcgttttcc agttttgcac ttatccattg atttattaca tggtaattat aaacaatatt 9781 gttttttgaa atagcattgt ttttaattgg tttgtttagt aataacacat cttctttgtc 9841 atttttttcg tctaacgcgt ataataatat agaaatggtt ataagtctct gctgtccatc 9901 tacaatatca tatttaccat tattctcgtg aagaattata tttccaattc taaaatcctt 9961 atttttaata aggatatatt cataaatatc ttctaagagc tgaaaaacat ttttatcagt 10021 ccatttatat ggtcgttgat actcagggat ctccagattt aatgttttat ctagcaaagc 10081 atttaatttt attatttctt gtgttggtgt tgtagccata ctattcctct ttataaaagc 10141 caaaactatt aaaaataata aaatatatat tttaacatgg gaattataat ttatcaaaca 10201 caattttaaa tcattatgtt tccctctatt ctattgtcac cagctgaaat aactcatcat 10261 aataatacac aaaacggcca tgctgaaaac caatgagtgc ttttttatcc ttttttttat 10321 aatttattac aacctctttt atcccaatac agggctctga tatgtgctcc cttgcaacac 10381 catttgagca cctatccaaa gatacatacc aaaagtcatt gcaaataagg taatactctt 10441 ctgtagccgc aaggaaacgg taccccttac gttcataccg tcctagtagt tctcttttct 10501 ctgtaccatt ttttatttca tagctaacta aatagttttc atcttgggtt atcatatagg 10561 tggataaaac agctactgtt tcctcttgca cataatcaat gtaccctata agagtgccaa 10621 ttccggtcac agatatttca tcatttgcag aaatgcctat agtaggtcat aattaccata 10681 tcatgtataa acaattatca gagatactta cggcggcccg attaatatcc cgtaccagcg 10741 gcgcaacgat taaggagctc gaaaaccacc tgcatctatc ccgccgttct gtatatcggc 10801 ttctggatac tttggaagaa cttgggtatc ccttgtatga tgaatttcat ggcaaagaac 10861 gggtcatttt tcttaatgaa caccgggaca acctgcgctg gtggattccc tatcctcagg 10921 tagagcttaa ctcagaagat atcatactct tagagtattt atttaaagaa gccgcaaaga 10981 cctcagcggt ggccaacgag ataagacggc tcaaagaaaa attggggccc ctgctggcag 11041 aaggcggcta cacccttgct ggcgaccttc atcaatctgg aattcttcct gcgccttccc 11101 tttccaaaaa gtttgatgca tctaaacacc agcttcttaa aaccatactc cagggcatac 11161 aagagcgcgc agtctgcatt gtttcctatc aagccatatc gagcgcaacg gtaaaaacct 11221 ttcgtattca tccccttata ttgatggaaa aatatggcgg tttgtacctt ttcgtgtttg 11281 ttccctacta tggaaacatt cgtatattag ccgtcgaacg cattaaaaac tttgagctta 11341 ccgaagaaga atttgctatg ccagcccact ttactcccga gccatggcta acagacccct 11401 ttggcattat actcaacaaa acctttacag cccgtatttg gttttctccg gaacaagccc 11461 cctatattca agaactgaat tggcccgaag ggtccaatct ggaaacccaa aatgatgggt 11521 ccctgatcct taccgtacaa acagccgctg attatgaact aaaacgctgg gttctcagtt 11581 tcggttcatc agcctgtttg ctcgaacctg agcatttacg aagggaaata caaaaggaac 11641 ttcaggatat ggaaaatctg tatcaataac taaaaaaatt tgacaataaa taaaagcact 11701 atctacactt agtacaagaa cgttccaagg ggttatccat gaagaacaaa acttttttcc 11761 tccttatttt agcaatgact ttgctattat cttcctgtat tgaaataacc caacatatca 11821 gattggaaaa caataccata ataaacaaca caagaattgt tattcaaaaa gccttgctta 11881 ctatggccca gagttatggt aatgattctg acctgtcatc acttgaattt aacgatgaaa 11941 caatctatca aattagtgaa caaataccaa aagaaaattt tgtatcaatt aaaaaagtca 12001 ataatgaatt agaaaatggt cttgagataa ctgttcgata cccgcgaact aaaagaccca 12061 cagtacagaa tgatgatgtt gcaccaatct tttatcccta tttaaaaaat aaaaccttgg 12121 ttgtagaatt taataatatg agttctacca atattgatga aaataatcaa atggtttcgg 12181 ctatactttc tggctttaaa tatcgcttgt ttattgatag ttccgtatta agttcaccca 12241 aaaaggcaac tttatatact aaagatgaag aaacgaccta tactatgcct ctaataaact 12301 attcaaactt tactctggta gaaatatcca tggcatatct cttaagcggc caatctttac 12361 gtttggtaat tgagtaaggg gcgcttttta agaagtctat tccaccaaca acgcccggtc 12421 gccagcaaat tcctgtttgc gaatttcgcg gaaacgatgt accagggcat ctacggtaag 12481 gctcgatttt tctgtgcctg agacatccat gatgatttca cccttatcca tcatgacgag 12541 ccggtttcca atagtgatag cccgagccat gtcgtgggta accatgatga ccgaaagctc 12601 atattcctgg gcaaagcgtt gagtaagttc caaaaccttt tccgcattgg cagggtccag 12661 ggcggcggta tgctcatcca gaaggaggat gcttggccgg gcaatgaccg ccataaggag 12721 ggtaagggct tgccgctgac ctccagaaag acggctcaca ttttctttca tacggttttc 12781 caaaccgata cccaattcgg caagccggtc ccgaaactct acctttcgcg cccgggtcat 12841 cgcaatggta aggggtttcc gtcccttccg ggccgccaca gccaggttgt cttccacggt 12901 catttctgcg gcggtccccg ccagggggtc ctgaaacacc cggccgatcg atcgggcgcg 12961 aaggtactcc ggttcgccgg tccgatcgat cccatcgatc actatggagc ctgagctggg 13021 gcgaaccgat ccggcgataa ggttcagcag ggtgctcttg ccggctccat tggaaccaat 13081 gacggtgaca aaatccccct gtccgatcat caatctaatg gaatttaaag cccttcgttc 13141 atcgggggta ttggcattaa aaacgacgat acaatcctgc agactgatca tagtacttcc 13201 tccgccttcc gttgcaggct tgcctgctga gcccgctggt cctgcagagc gcttttccac 13261 tgaccgagaa caagggaaag gacaatcatc agggcggtga gaagcctgag gtcgttgggg 13321 gtaatccccg cgatataccc ataaaaccgg gccccaaaga gaatcgcctt aaagatgatg 13381 gcccccagca ctacccggaa cagctgaagc ccgatccggt tggttctgag gaccagttcg 13441 ccgatcatta ccgaggcaag tcccagggca acgacgcctg ccccaaggtt tacatcggca 13501 aaaccgtggt gctgacttgc cagggcgccg gcgaaggcaa cgagggcgtt tgccagggcg 13561 accccggcgg ctttaaaggt cgtcgggttc gaaccggaag caatgaccac ttttacattg 13621 tcccctaagg cgcccatcgt aaggccgaac tcggtgtgaa aaaagaggtc cagcagcacc 13681 atgatgatga tggctagtag caagaaaaag agtgcacttg ccacttcagg gggcaaggcg 13741 ggaaaccagg tggcgctaaa ctgtatgagg gggcggttgc tgatgagctg gatgttggat 13801 cggccgccca taacacgcag gttgatggaa tacaggcccg tcataacgac gataccggcc 13861 agaaggggcg gcaccttaag tcccgtgtgg atgagggatg tcattgttcc cgccagggcg 13921 cctgcggtta tcgcaatgag ggctgccacc gggaagggga tgcccgctgt aagacagcta 13981 gccgcgaccg cagcacccag gggaaaactc ccctccacgg tgaggtcagg gaaatcgagg 14041 acccggaagg tgataaacac ccccatggcc aggatgccgt aaattaagcc ttctaccagt 14101 atcgctgaaa tcatgaagta cgaaccttac ccttagtttt acttgccgat aacgagggat 14161 gcccgatcta tgtaggcctg gggtacggtg acaccgattt ttttagctac atccagattg 14221 atgaccagag cctgttcttt ggggtccttt gcaaagtatg tgggaatatc ggcggtcttt 14281 ttgcctttaa gaacttctac cacgatgcgg cccgtagcct tacccatttc gtagtagtta 14341 aagcccactg cggccagtac gggaacggtc tcagcagaac tggggtccgc cgttaccagg 14401 ggcaattttg cctttaggca gatatccgcc acggtagaaa tagcggaaaa caccgtgtta 14461 tccgtagaca ggtaaatacc atcgacccgg ccgacaaggg atgtcaaagc ctgggaaact 14521 tcagcagaat tggtaaccgt ggcggtaaca aactcaagcc ccttggactt aacataggct 14581 tctgccttgg cggcggtggt aaccgagttg gcttctcccg cattataaat atggccgatt 14641 cgcttaatgt ttggggccag ggcgatgagg gtatcaagct ggccttccag gggcggcagg 14701 tcagacgtac cggtgatatg ttcgcccccc ttgtcatagg aagccacaag gcccgccgca 14761 acggggtcag taacggcaga atagatgaca gggatgtcgg taagcacatt agccagagcc 14821 atggcggtgg gggttgcaat accgaccgcc acattgacct tatcaacctt gaatttctgg 14881 gcaatctggg aagccgtggc aggttctccg ttggcatttt gtaggtcaat ctttgctttt 14941 gggaaggcag cagttatttc ttctacaata cctttttcca aggcatccag ggcaggatgg 15001 gctactattt ttgccacacc gattttcggt tcatcggata ctttttttac tgaaccggca 15061 ccgcaggcgg ccagggctac aagtcctagg ccaatcaggg tatagccaat cattttcacg 15121 cttttcttca tattactact ccttaatgtt tcttttaata gaaacgttta caaaatatac 15181 cgatacggat gaactatgtc aagttaaaaa ggacttaaga agtttatttc accgcttcta 15241 tggcagactg taaggccgct tccagcattt cctggggtgg ttctttaata tgacctaacc 15301 gttgcatatc tgccactaaa gagcgagatg cggcaatgtc tgcctttgct tgctggtata 15361 cctcgtccca ggtcatggga accctggcta catcctccgc aatggcctgc atggccacat 15421 cggccgcttc taccgcaaag acctcggttt cttccatggt ggcaattata ttttcagggc 15481 taatcccccg tcgttccgca aagtcggcaa ttgagtgggc acagcggatc gccataccat 15541 cggtaatttt tctggatcga actaaaaggg ctcctttcag gattcccgga aagcaaaccg 15601 aattattcac ctgattggga aagtcacccc ggccagtggc tacaatgtaa gccccttctt 15661 ctttagccgc atagggccag atttcaggta ccggattggc acaagcaaag actatagcct 15721 tttccgccat agagcgaacc cattcccgtt taaccgtatc cggtccgggc gtagaaaggg 15781 caataagaac atcggcaccc ttaatagctg tgtccatatc cttaataccc tgggggttgg 15841 ttttttggca aagctcccat ttccggtagt tgcgggtatc agtttctata tccttccgcc 15901 ccgtatgcaa cgaaccctga gagtcgaaca tgataatctt tgccggatct gccccatcgg 15961 tcatgagcag gcgggcaata gtcgtgttcg atgcccccgc accaagcaac acaatccgga 16021 cctctgaaag ttttttattc accaacttca gcgcattgat gagccccgcc aaggtgacac 16081 aggcggttcc ctgggcgtca tcatgccaga ccggaatatc gcaagtctcc cgcagttcat 16141 caagaacctt aaaacaattg ggctgactga tatcttccag attgatggcc ccaaaggaat 16201 gctggaccat ttttacaaat tcaataattt tatcggggtt gttttttccg ctggcatccc 16261 gggaatcgac acagaggggc accgcatcca caccgcctaa gtatttcatc aacatggcct 16321 tcccttccat gaccccgagg cctccagggg gcgtacagtc tccgtcccca aggacccggg 16381 tggagtcgga aaccaccgcg accatgtttc cccggctgga aagcgcaaag gagctgtcat 16441 tgtcatcccg tatggtggtg gatatttttg aaaccccggg ggtgtaccag acattgaacc 16501 agttaaaacc aaaaatgccg caccggggca gggtctgcat tttaccacca taaaattgat 16561 gagcttcgag agaaagattt ttgagaaaga gggtcttggc ccgggctttt tgctcttcgg 16621 taaaatctcc agggaagagg ctgtccagat ctttaagact aatatctacg ttcatgtggc 16681 aatccttatt aagttaccgg atgcactagc agtgagtacc ggctattttg gcgtcagatt 16741 accacgaaac tatgtgaata tccagaacca gagacatttt atacaatcta aaagttggat 16801 ttataaaaga actatacatt ttattgaagg acatattata cttattacgt atcatacata 16861 ttatgtatgg aggtttttat gcctaatgta acgatgagta ttgatgaaga actattaaaa 16921 tctgcccgaa aaatagccat tgaaaaaaat acaaccgtat ctgatatggt ccgatcatac 16981 cttactaact tagtaaaatc ggaaacaata cgacgagaat atgtagcaga tgaacttgaa 17041 cggcttttta ataaaagcac cgcccattcg cagggtatac gactgactcg ggatgcgctc 17101 catgaccgat aaaataattt ttcttgatac caacatttta gtatatgcta atgacaatgc 17161 ttatccagaa aagcaaaaaa ttgcacggaa ctatattcgt gaggttatta taacaggaaa 17221 tggatacatc tctacccagg ttttggctga gttctgggtt acagttactc aaaaactacc 17281 cacatgcctt tcacaagacc tagctcggga acaaataagt cttttttcga actttcatat 17341 aataccagtt gaatacccaa ctattttaga ggctattcgg cttcaagaac ggtatcaaat 17401 ctccttttgg gacgctcaaa taatagcctc tgcattacag gtaaatgcaa cggtactgtt 17461 gactgaagat ttgcagcatg ggcttagtat aaattctatt acgatacaaa accccttttt 17521 ataattgggc ccgggaagct tttttagaag cataccaaag cagtactgct acaggaacaa 17581 tcagcacgag agcaatcaga ttaccacgga acaattcaaa tatccagaac cggaggggat 17641 ttccaccatc ggtgaaggag ctcaccacga ggcttgagcc ttccgataca ccgggaattg 17701 tcccagcctt ctgggcaagt tcggtaataa gcggccccag agctgtagca ctatagagaa 17761 aagcaataat aaccggcaag gcaataagaa tggctcggat cacattgccc ccgcttataa 17821 gcactactac agaaaagatg gacatgagat ttggcaaatc cccagcagga agcactttgt 17881 ttccaggcag tacaaaggcc agggcaagac tgatgggcat taaaagcatt ccggttacaa 17941 tcaccgaggg aatcttcatt aaaaagcccg tatccatagc aatggctatg gttcgtcttc 18001 caaaaagggg tgccatccgt tcagacgcag cccgggaaat agaacctgtc gcatcaccaa 18061 tcagggatcc gcaatggggc agaagaaaca taatcgccgc aattttaacc gccgtctcga 18121 ggatctgctt cacatcatag gctgccaaat acccgaaaag gaggcccata aataaaccaa 18181 caatcatggg ttccccgagg actgcccagg ggccttccga ccgggaagga ttccaatgga 18241 gccagcgcaa gccagggatt ttttcgatga ccgcatccat agcaatagcc cagggtgcaa 18301 aaccggcaac cgtaagagga ctaatgctca ctccggtaat tcccgccaca ttctggacat 18361 agggtgtggt catttcggac attttaaaaa ccagcagggc cgcaaataaa ctgccagcaa 18421 gagcaagcgg cagcggaata ccaaccgcca tgagcataga gccaatcagg gcaaaatgcc 18481 agtagttcca gatatcaata taaaaaaccg tggtccaccg gaggaggagc attaacacat 18541 tgaggaacag cacgaggaga atgatgaggg gcgcaatcca tgaagaccag gttatggcgg 18601 caaggggcgg ccatccggca tcgataatag gaaactgaag gttccgagct tcgaccatgg 18661 cttgaaccgc agggtgcatc atgccaagaa aggcatcaaa aataagaaaa acccctgcaa 18721 aaccgatgcc tactttaaga gattggagaa gagcctttcc gagaggcatt ttggaaaaca 18781 gggcgatgat aaagaataga attggaagta agagatatac cttaaatgaa aaaatccaac 18841 taatcacatc gcttaaaacc tgcat //