LOCUS NC_014650:16 19134 bp DNA linear BCT 06-SEP-2013 DEFINITION Geobacillus sp. Y4.1MC1 chromosome, complete genome. ACCESSION NC_014650 SOURCE Geobacillus sp. Y4.1MC1 chromosome, complete genome. COMMENT locus start: 3438466; locus end: 3457599 COMMENT n1_4mer:GRV/n1_4mer:RV = 2.192604; n0_4mer:D = 29.380269; n0_4mer:PS = 23.174042 FEATURES Location/Qualifiers source 1..19134 /organism="Geobacillus sp. Y4.1MC1 chromosome, complete genome." gene complement(1..735) /gene="" /locus_tag="" /db_xref="3438466..3439200" CDS complement(1..735) /gene="" /product="CRISPR-associated protein Cas5, Hmari subtype" /translation="MKMLIFDLIGKMGHFRKIDTNSSSLSYAFPPRTTIVGMIAGILG MERDSYYEVFSPDQCQIAISVRTPIRKVMQTVNYMFVKSKAHLNNSGGHTQIPLEFVL PGGEEANLRYRIYFSHSDRSVYESVKERIQSGRYVYPPYLGLSELLGQLQWVAEAEGM LKESNDLVPIHSVVRIPDLRERSIQFSRDTRFLKEFMTRQFTNERMIQETDYYLFEQS RQLIAVPAVPYIAVAYGEAKENILWM" gene complement(750..1685) /gene="" /locus_tag="" /db_xref="3439215..3440150" CDS complement(750..1685) /gene="" /product="CRISPR-associated protein, Csh2 family" /translation="MNNSDILFLYDAKLTNPNGDIDEENRPRMDYERSLNLVSDVRLK RYIRDYLEQIGHEIFVGKVDGETVNATERMKRLFEKYDGKVNINKLSKEQQNWMLDQF IDVRMFGATMPIKSEDKGSSMTFTGPIQFNWGYSLNKVTLVESASITSHFGSDDKNDG GNIGKDYRVYYSFLAFHGVISGHRAAHTRLTEEDIHLFDQAVVKAIPLSATRSKVGQY PRLYVRVEYHSPEFIAGDLRDLVHLEETEGLRSISEVTLHVDALVNKLLEVNGEIARI HYWQDSNLTLNYEGQKGLLADLLPSELADKLVSVL" gene complement(1848..3818) /gene="" /locus_tag="" /db_xref="3440313..3442283" CDS complement(1848..3818) /gene="" /product="CRISPR-associated protein, Csh1 family" /translation="VIKTIYTLGSKYLTEEKPSMIQAMTLPIAKSDGATKYVVIVDFS IAEKKIRLTPKEIGASTSSELLWIGTADGAASPQWYGTVSNVEYLLSQTIPNLLERWD QKDFYYSLLKEARDVFFLDLGAAKKSDERYRYVFNPAYVSGELTETEGKKAVKEVAKQ FQAFMEKEANVNIKDVLLYSLAINGQLVVSQPEYERLVIAEKLSVFEDAKKGVCALTN KEAFVTGETTKLKFNYYINDKISFASDLEKKSFVKNLSISKDAYQAIMAGEAYILRHF NTRFSGLPCYIIPDFLYDVPFANVPLQDISEHIHQFVRTVKTVETAEDLHREIEDYKE FDEQMDNHISLHFLFYTKAQSALKVNKLLSDVPLTHLRRLSFEMRKTGEIGQRFFGSE KFNLGLEPIYYLIPMRVQRGENFEKRKILQVYESLLTNKPLSYRWLITQFVQLAKVHM YANYNLYQYSSDKEEPNDFRLVNAMVRAQLFLKMLQNLNLIKEEREMTKVTYDLPDAH MIEYMETMNYNVAQSSLFLLGYLIAKIGAEQVRRTKARAEALGQAWGGKTVNKPILSK INYHGMNKQRLMLLSHEVFDKLRQLKIASLQNETVYIEHKRLFDLALQEKWNLSDRES VFYLLSGYAYGTKRILNSSKKDNSDPDFENEE" gene complement(4002..4181) /gene="" /locus_tag="" /db_xref="3442467..3442646" gene complement(4318..5073) /gene="" /locus_tag="" /db_xref="3442783..3443538" CDS complement(4318..5073) /gene="" /product="DeoR family transcriptional regulator" /translation="LLAIERRQKIIEIIQKDKRALVSDLSKRFNVTEETIRRDLEKLE KEGIVTRTYGGAILNQHTNVDLPFATRKDINIPIKQEIAKKAINYIDERDSLFVDSSS TCFELVKLLENNRIVTVITNSAKILNEISSDSLHIISTGGTLRPYSSSLVGSIPQETV KKYNTDWAILSCKGIDMNRGIMDSNELDAELKKVMVQQASKTMMLVDHTKFDKVAFTS FLDFQQIDYLVTDKKPSDEWIKFLHEQNVTVIY" gene complement(5483..5777) /gene="" /locus_tag="" /db_xref="3443948..3444242" CDS complement(5483..5777) /gene="" /product="" /translation="MAKKVQTFHIYSEERKREVVRVKLEGAGLICSSANILELRAQMA KWIKKIQRGESLKDQRGVWNRKHFSSLEKENAYWKVQVEWLKSTSQFTREGIIL" gene complement(5998..7275) /gene="" /locus_tag="" /db_xref="3444463..3445740" CDS complement(5998..7275) /gene="" /product="hypothetical protein" /translation="MADGAKGGLKATITVAMSNYLEAGSIVAGAGGLSLWVEYLKLDD IKVGLLGAVSANGFGSAVGAFIGGILVDRFGRKFIYKYDLLVYMLGVLLITLSFNFPM LLLGYIITGLAVGAGIPAAWTYISEEAPANERAARVGWGQFARSVGPVISLLLSVLLA PLGILGSRIIFAQLFVVAAITWIMQQQIRESMIWEEERQKQAELKAKYQISKSSTKEL FTIKANLHAMILLIGIYCFWNLVAGVMGYFMPYIYEKVGGLTAAQANLLQAFLWILTV ASTYFVFIKLGDKVNRRVLYGLGALMEIVAWIILSFAGMGKIQLMLFVILWGTAAGFG AQAFYALWAGELFHTKYRAKAQGFLFSVARIAVGLISLVVPTMITQLGFKFAGTVMIG FLLIAAIIGVAMAPETRGKTLKEIQQERYGTNY" gene complement(7369..7683) /gene="" /locus_tag="" /db_xref="3445834..3446148" CDS complement(7369..7683) /gene="" /product="L-rhamnose 1-epimerase" /translation="MIRKASIMFVNKDSYEEYKRRHDEIWPEMVTELKAHGAHNYSIF LDKETGRLFAYLEIEDEKLWEQMAETEICQKWWKYMKPIMKTNPDNSPVSINLDEVFH LE" gene complement(7716..8549) /gene="" /locus_tag="" /db_xref="3446181..3447014" CDS complement(7716..8549) /gene="" /product="rhamnulose-1-phosphate aldolase" /translation="MTGKLDILTAEFTQEMMKTTANLYRLGWDERNGGNISYLLKEEE VIPFLDINHVKRTMPIHFDASALAGKYFIVTGSGKYFKNVMDKPAENLGVIRVTEDGK AVDVLWGFEDGGGPTSELPTHFMSHIERLKADPNHRVIIHCHATHILGMTFTHSLDEK AFTKTLWQMCTECIVVFPEGVGIIPWMVPGTDAIGKATAAKMKDVRLVVWPHHGVFGA GTTMDEAFGLIETAEKAAQVYTIVCAQGGVKQAITDQQLLELADAFGVVPRQGILNTK K" gene complement(8561..9823) /gene="" /locus_tag="" /db_xref="3447026..3448288" CDS complement(8561..9823) /gene="" /product="L-rhamnose isomerase" /translation="MITSEVQEAYELAKKAYAKYGIDTDRVLDQLKNIKISLHCWQGD DVRGFINKDQALTGGIAVTGNYPGAARTPDELRQDLEKAFSLIPGKHKLNLHAIYVDT DEKIDFDEIEPRHYQKWVEWAKEQGLGLDFNPTCFSHPKADDGFTLSHPNKEIRDFWI EHCKRSRKIGEYFGKETGQTCVTNIWIPDGYKDIPVDRLAPRKRLEEALDEIFEEEID PKFNLDAVESKLFGIGSESYVVGSHEFYIGYALTRNKLICLDMGHFHPTETVSNKLSA LSLYSNGMLLHVSRPVRWDSDHVVIMDDELQEIARELVVNNLLEKTYIGLDFFDGSIN RVAAWVIGARSMLKALLRAFLEPIELLKEMELKGDYTSRLALREEFKSYPFGAVWDYY CASQGVPVREEWLAEVKNYEKEVLLKRI" gene complement(9792..11264) /gene="" /locus_tag="" /db_xref="3448257..3449729" CDS complement(9792..11264) /gene="" /product="rhamnulokinase" /translation="VIYVAVDIGASSGRLVLGEIKDNKLKIKEIHRFSNGFTVKDGTC YWDIDYLLNEILKGLQVVKSLGYDQCTVGIDTWAVDYVLLDQKGKRLREVVSYRDGRT KQTIEKVTKLVSKEKIYKKTGIQFLPFNTIYQLYEEDQEKLKNTNQILMVPDYLGYCL TGVAVTEVTNASTTQLLNLNSRTFDDELLDLISVKREQFARLVEPGTELGMLKKEWFS SFDLPNCKVITVATHDTASAVIGTPGFGENWAYLSSGTWSLLGIESAVPIVNELALQH NYTNEWGAFQTIRFLKNIIGMWIIQEVRRHLEQDYDFSQFVEEAKKVKGFHQFINFND ERFMNPANMIDEIQTYCKETNQKVPETVGELANCIYNNLAIIYAIAIQELEEITGKTI DQLHIVGGGAYNEHLNQLTADLSGKVVYAGPTEATAIGNLIMQMIATKEVKDLEAARQ LIRDSFEIKKYTPNEINRQAIIQKFKEVVLYDHVGSTGSL" gene complement(11354..12508) /gene="" /locus_tag="" /db_xref="3449819..3450973" CDS complement(11354..12508) /gene="" /product="iron-containing alcohol dehydrogenase" /translation="MSNAHVFYVPSTNLMGRGCLAKVGPFIKEFGFKKALVVTDKFLH KSGIAGKVLAVLDEIGVNYVVYDDVKPNPTTKNVYAGADLFKKNECDFLVSVGGGSPQ DTAKAIGLYVTNGGDIRDYEGVNKTKNKSVPIVAVNTTAGTSSEFTINYVITDEERNV KMVMVDKNSLVTISVNDPELMVDKPAALTAATGMDALTHAIEAVVTPGSYTVTDATAL AAIEIIFNYLPRAVKNGHDIEAREQMAYAMFLVGIAFNNAGLGMVHAMAHQLGGMYDL PHGVCNAMLLPIVERENAKRDPRKFRAIAKAAGIDVTGKTDEQCAEEVIEAIKALSRE IGIPSKLSELGVDEVDLEKLANNALKDACAPGNPFQPTKEEVISMFKEIL" gene complement(12836..13015) /gene="" /locus_tag="" /db_xref="3451301..3451480" CDS complement(12836..13015) /gene="" /product="hypothetical protein" /translation="MQSMHFGDELFTVYAKLARKSDISFQTSRIFTILREDTVIIQKH LHRCFFVYVYKKYGL" gene complement(13163..13609) /gene="" /locus_tag="" /db_xref="3451628..3452074" CDS complement(13163..13609) /gene="" /product="YbaK/prolyl-tRNA synthetase associated protein" /translation="MDNLKSILQENDVQFEVIHHESPIHTAQEGADYFGIEIGQTAPT LVLKSEKGYFAMIISGGRGRVNLEEVSEILGCNQLKMATPKEVQQITGYTVGSVPLVG LSLPCIVDKELFRYPFIYGGTGESTSTLKIAPNALEKLNQVVALLD" gene complement(14071..14539) /gene="" /locus_tag="" /db_xref="3452536..3453004" gene complement(15107..15538) /gene="" /locus_tag="" /db_xref="3453572..3454003" CDS complement(15107..15538) /gene="" /product="hypothetical protein" /translation="MKEKIKQLITSGDFQKAKEYIENEDRNTLEQVVLELGFDEESIS AYSFVCYLINNNETADYHYLASELLSTALCHLPDAYASALYHAKRAVELSPEDVSLKE HLLLFYEIPEKLISKEEAKAIAQEILKIITDNKMGKSCNFI" gene complement(15855..16352) /gene="" /locus_tag="" /db_xref="3454320..3454817" CDS complement(15855..16352) /gene="" /product="hypothetical protein" /translation="MENLEIILLDFRKEEIETLIHEELKLSTLNIKSSHFYDFNSGKD MEFPQVKNMKEILSPKGTGNIVLEQLQLGITLKNVVIVFSFDEECGDIVFNFPESEIF IGDKKEVKSRFEKLVNYLVKLKMKYNIPKVIIGYEPADDEDTMLIELSDNALNLEKVL EKILD" gene 16594..18123 /gene="" /locus_tag="" /db_xref="3455059..3456588" CDS 16594..18123 /gene="" /product="Integrase catalytic subunit" /translation="MLAMPEIHYIKHLRENKDLSISEIARKTGLNWRTVKKYADGNIG GQKIMKKKRGMMYELGYGEIIDDWLEEDAKLPRKERRTNRTMFEQLQKEHGFPGSYRT VCAYIQERKPHLKAEKEKRYERLEHPPGEAQVDFGTMQVVKDGALEDKKLLILSFPHS NAGFAHPLPSENRECFLEGLKQLFHQAGGVPRRLRMDNLPAAVVTVGKGDNRQYTEAF LRFQAHYGFEVQPCNPASGHEKGNVERKVYYVRHRCFVPAPVVESDEQLTEWLRVKMI EDRSRLHYEKGVPIEELWKEDQKELKALPLDDLPIFSLDTVKVNKYGEITVDGEKWVI HQARVNQSLVVQKGWDRFICLSNQGEVVFEAPRPYMNQKQEIPWEEIFNDWEKKPRSV SYSRFFKYLPEKVQTYLTFRKEEVKQRVRGVRELLKSHTLKELDEWLNKEQRFDLAPH ELKVLLEAKQQAYPEKWEETYTPSVFVNYETDLHLYDQRLCPSWEGGANRDDSGHQRD L" gene 18095..18835 /gene="" /locus_tag="" /db_xref="3456560..3457300" CDS 18095..18835 /gene="" /product="IstB domain-containing protein ATP-binding protein" /translation="MTRDIKEICKALHLAYIADRFEEVPYETKEQFLRDVLALEVSSR QEAKRSKLIKKAKFRELKWLKDYEWSDHIHWPSTTTKEELCDLVFLERRQNVLLLGSP GTGKTHLATALGLKACEKGHEVRFFRVADLVAQLEEALKNGTLPRLKRQIETCELLIL DELGYVPFQKQGSELLFHIIADCYERKSVIVTSNLEFGQWNRVFGDNRLTAALVDRLV HHAHIIAFTGESYRLRHALSSVKKISSN" ORIGIN 1 ctacatccat aaaatgtttt cttttgcttc accataagca acggctatat atggtacagc 61 cggaacagcg attaattgcc gcgattgttc aaacaagtaa tagtctgttt cttgaatcat 121 tcgctcattt gtaaactggc gtgtcataaa ttcttttaaa aagcgggtat ctcttgaaaa 181 ttggatcgat cgctcgcgca aatcagggat tcgcacaaca gaatgaatcg gcaccaaatc 241 attgctttct tttaacattc cctctgcttc ggcgacccat tgcaactgcc cgagtaattc 301 agaaagccct aaatacggcg gataaacgta ccgtcccgat tgtattcgct ctttcacgct 361 ttcataaaca gagcggtcgg agtgggaaaa ataaatgcga taccgcaaat tggcttcttc 421 tcccccggga agcacaaatt caagcggaat ttgcgtatgt cctccgctat tgtttaaatg 481 ggctttggat ttgacaaaca tataattgac tgtttgcatc actttgcgaa tcggcgtgcg 541 cacagatatc gcaatttggc attggtccgg cgaaaatact tcataataac tgtcgcgctc 601 cattcctaaa ataccagcga tcattccaac aatcgtcgtc ctcgggggaa aagcatatga 661 caaggaagag gagttcgtat cgattttccg gaaatgcccc atcttcccga taaggtcaaa 721 aataagcatc ttcataaacg tcaccctttt tacaatacag aaacgagttt atccgccaac 781 tcggatggaa gaagatctgc caacaagcct ttttgccctt catagttcag cgttaaatta 841 gaatcttgcc aataatggat gcgggcaatt tcaccattta cttccaaaag tttattcaca 901 agtgcatcaa catgcaaagt aacttcggaa atgctgcgca gcccttctgt ttcttctaaa 961 tgcactaaat cccgcaaatc gccggcaata aattcaggag agtgatattc gacacgcaca 1021 tacaaacgcg gatattgccc gactttgctg cgggttgcgc tcaacggaat tgctttcaca 1081 accgcctgat caaacaagtg gatatcttct tccgtcaacc tcgtatgtgc cgcacgatgg 1141 ccacttataa cgccatgaaa cgccaaaaat gaataataga cgcgataatc tttaccgata 1201 ttgcctccgt catttttatc atcggaaccg aaatgcgacg taatgcttgc cgactcaaca 1261 agcgtcactt tatttaacga ataaccccag ttaaactgaa tcggaccagt aaacgtcatg 1321 gagcttcctt tatcctctga cttaatcggc attgtcgcgc cgaacatacg gacatcaata 1381 aattgatcaa gcatccagtt ttgttgttct tttgataact tattaatgtt caccttgccg 1441 tcgtacttct cgaacaaacg tttcattcgt tccgttgcgt taaccgtttc cccatcgact 1501 ttgccgacaa aaatttcgtg accgatctgt tctaagtagt cacggatata ccgtttcaaa 1561 cgaacatcgc tcactaagtt taacgagcgt tcgtaatcca tgcgcgggcg gttttcttca 1621 tcaatatcgc cgtttgggtt tgttaacttt gcatcataaa ggaataaaat atcgctatta 1681 ttcattttca ttcctcctca tatattagta aattttgcag tttattgatc acgccttgac 1741 catttatttg gaaggaagag tttccctcac tttatacggg attgggcttt ttgatattcc 1801 tccaaataaa ttgagggaat ctcttcttct ttgccattcg caatgcttta ctcttcattt 1861 tcaaaatcag gatcggaatt atcctttttg ctgctgttta aaatccgctt tgtgccatat 1921 gcgtagccgg acaacaaata aaaaacgctt tcacgatcgg ataaattcca tttttcctgc 1981 aacgctaaat caaaaagacg tttatgttct atataaacag tctcattttg caaagaagcg 2041 attttcagct gtctcagctt gtcaaatacc tcgtgtgaaa gtaacatcag cctttgctta 2101 ttcatgccat gataattaat ttttgataaa atcggcttat ttaccgtttt gcccccccag 2161 gcttgtccaa gcgcttctgc acgtgctttt gttctccgaa cttgttcagc gccaatcttc 2221 gcaattaaat atccaagcaa aaatagagag ctttgcgcga cgttataatt catggtttcc 2281 atatattcga tcatgtgggc atcaggcaag tcatatgtta cctttgtcat ctccctttcc 2341 tccttaatta agttaaggtt ttgcaacatt tttaagaaca attgtgcccg caccatcgca 2401 ttcactaatc gaaaatcatt gggttcttcc ttgtcgctac tatattgata aaggttatag 2461 ttagcataca tatgcacttt ggcaagctgc acaaattgcg tgatcaacca tcggtatgaa 2521 agcggtttat ttgtcaaaag cgactcgtat acttgcaaaa ttttgcgttt ttcaaagttt 2581 tccccgcgtt gaacgcgcat cggaattaag tagtagatcg gttccaagcc gagattaaat 2641 ttttcgctgc caaaaaagcg ttgcccgatt tctcccgttt ttcgcatttc gaaacttagc 2701 cggcgcaaat gagtgagcgg aacatcggat aacagcttgt tcacctttaa agccgactgc 2761 gcttttgtgt aaaaaagaaa atgcaacgaa atatggttgt ccatttgttc gtcgaattct 2821 ttgtaatctt ctatttccct atgcaaatct tccgctgttt caaccgtttt gacagtgcgg 2881 acaaactgat gaatgtgctc actaatatct tgaagcggga catttgcaaa cggcacatcg 2941 tatagaaagt ctgggatgat ataacaagga aggccgctga aacgagtatt gaagtggcgg 3001 agaatgtatg cctctcctgc cataatcgct tgataggcat ctttgctgat ggataagttt 3061 ttaacgaatg attttttctc aagatcgctt gcaaagctga ttttatcatt gatataataa 3121 ttaaacttca attttgtcgt ttctccagta acaaaggctt ctttgttcgt aagggcgcat 3181 actccctttt tcgcatcttc aaatacgctc agtttttctg cgataacaag ccgttcatat 3241 tctggctgcg aaactacgag ctgtccatta atggcgaggg aatacaaaag gacatccttt 3301 atattgacat tagcctcttt ttccataaaa gcttgaaatt gtttcgctac ttccttaacg 3361 gcctttttcc cctctgtttc ggtcagctca ccgctgacat atgccggatt gaaaacataa 3421 cggtatcgtt catccgattt ttttgccgcg ccaagatcca gaaaaaaaac atcgcgtgct 3481 tccttaagga gggaatagta aaaatctttc tgatcccagc gttcgaggag atttgggatc 3541 gtttgactaa gcaaatattc gacattgctc accgttccat accactgtgg gctcgcggct 3601 ccatccgccg taccaatcca cagcaactct gaagatgttg atgctcctat ttctttcggt 3661 gtcagcctta tttttttctc cgcaatagaa aaatcaacaa tcacaacata tttggttgca 3721 ccatctgact ttgcaatcgg caaggtcatc gcttgaatca tagatggttt ttcctctgtt 3781 aaatatttac tgccaagagt gtagattgtt ttaatcaccg tctgcacctc ctttaaagaa 3841 aaatgtaaat ttttgttgtt tgtttaaatt ttatcaatat taactgttat ttcaatattt 3901 tcatatatta tttaacattt tattcaaaaa tacgaatgac tttttaagct taacattttc 3961 ttaaaatcca gacacttaat ctaaacccta ttttgatgaa aaaagggctg gaatcgcctc 4021 catagccatg tagctagttt ttttaaattc atggcaacac aaaaaaagca tcgcctgcct 4081 taaaaatttt tccggacccg acaggccgtc taatgcagac catgcttctc tttcatatcc 4141 gcaaagactc gttcaattgt ttcttttctc cgaacatagc aaaacaaata tagatagtga 4201 ctgcccttag ttggggttac tgtcttcttt ttcactaaac tatgatcaga aaatctgatt 4261 caatttatta tttttatgcc acgctactgt tttacttctt cttaatttat ccataaatca 4321 ataaatcacc gtaacatttt gctcatgaag aaactttatc cactcatcag atggcttttt 4381 atctgtaact aaataatcaa tttgttgaaa gtctaagaaa cttgtaaacg caactttgtc 4441 aaatttcgta tgatcaacaa gcatcattgt cttacttgct tgttgaacca ttactttttt 4501 taactcagca tcaagttcat tggagtccat aattcctcta ttcatatcta tccctttaca 4561 gcttaaaata gcccagtctg tattatattt ttttacagtt tcttgtggaa tagaaccgac 4621 aagcgatgac gaataaggtc ttagtgtacc ccctgttgaa ataatatgta gactatcact 4681 tgagatctcg tttaaaattt tggctgaatt tgtaatgaca gttacaatcc ggttattttc 4741 caacaatttt acgagttcaa agcaagtaga actggaatca acaaacaatg aatcacgctc 4801 atcaatataa ttgattgctt tcttcgcaat ttcttgcttt attggtatgt tgatatcttt 4861 tctcgttgca aaaggcaaat ccacattcgt atgttggttt aaaatggctc cgccatatgt 4921 acgtgtaacg ataccttcct tctcaagttt ctccaaatct ctcctaatgg tttcctcagt 4981 tacattaaat cttttgctta aatcagacac taacgcacgt ttatcttttt gaatgatttc 5041 tataattttt tgtcgtcttt caatggctag caaattaatc aacccctaaa tcacgaccag 5101 tattaatttg attatcttta ttataaccaa ataaacaacc agaaataatg gttttatgca 5161 aggcagtcta atatttttta ttgaaaacta ttttgaatgc acataaccct gtcaagtaga 5221 caattatatt aagctccggt cttttcgcga tattccaccg ggaaaaggcc gttccatttt 5281 tctcggaaac cactatggtt gtaaaaagaa ataacgccct tgacattcta cggatggaaa 5341 acagcttcca gacgtaatgc ccttttagat cggcttttgc gccatttgta gtatcaatct 5401 ttggaaactt cgccaattca gaataaccat gcaaatggat gttttttccg taacttatcc 5461 ataatgagaa acttttctga ttttaagata attccttccc gtgtaaattg ggatgtgctt 5521 tttagccatt ccacctgcac tttccagtac gcattctcct tttccaaact ggaaaaatgt 5581 ttgcgattcc acactccccg ctgatctttc aatgattcac cgcgttgaat tttcttgatc 5641 catttggcca tctgggctct taattccaaa atgttcgcgg agctgcagat aagaccagcc 5701 ccttccaact tcacacgaac gacttcccgt ttccgctctt cggaatagat gtgaaaagtt 5761 tgtactttct tcgccataaa aaatcccctc ccaagtagac tcttaagcac atcatatcaa 5821 atcgctgtct acttgtaggg gataatacca ggctgcttaa tcagccatct tttttaatta 5881 ctgtctgctt gacaggagta agaccaaaac ctcacctctg agtgatgctg agccattccc 5941 tttttaaggt ttaaatttta acctctgatg gactgttgca tctcgtgaga caactcatta 6001 gtagttagta ccatatcttt cttgttgaat ttcttttaat gttttccccc tcgtctccgg 6061 tgccatggca actccaatga tcgcagcaat aagcaggaat ccaatcataa ccgttccagc 6121 aaatttaaat cctaattgtg taatcatggt tggaaccact agtgaaatta atccaacggc 6181 tatacgagca acactgaaga gaaatccttg ggctttagca cgatatttcg tatggaaaag 6241 ctcgccggcc catagcgcat agaatgcttg agctccaaaa cctgcggcag taccccataa 6301 gataacaaag agcatcaatt gaattttacc catgccggca aatgagagaa tgatccaagc 6361 aacaatttcc attaaggcac caagtccata aagtacacgg cgatttactt tatcacctaa 6421 cttaataaat acaaaatatg ttgaagccac cgttaaaatc cataagaaag cttgtaacag 6481 attagcttgt gctgcagtaa gtccgcctac tttttcgtat atatatggca tgaaatatcc 6541 cataacaccg gcgactaaat tccagaagca atatattcct atcaataaaa tcatcgcatg 6601 cagatttgct tttatagtaa ataattcttt agtagaactt ttggaaattt gatatttagc 6661 tttaagttca gcttgttttt gcctttcctc ttcccatatc atagattcac gaatttgttg 6721 ttgcataatc caggtaatgg ctgcaacgac aaacaattgg gcaaaaatga tcctacttcc 6781 taaaatccct aatggagcta ataatacaga aagtaacaag gaaatgacag gacctaccga 6841 ccgagcaaat tgtccccatc ccacacgtgc tgctcgttca tttgcaggag cctcttctga 6901 tatatatgtc caggcagctg gaattcccgc acctactgct aagcctgtta taatatatcc 6961 taataataac atagggaagt taaaagaaag cgttatcaat aaaacaccaa gcatataaac 7021 aagaagatca tacttataaa taaattttct tccaaacctg tcaactaaaa tcccgccaat 7081 aaaagcacca accgctgatc cgaaaccatt tgcactaacc gcaccaagta aaccgacttt 7141 aatatcatct aactttaaat actctaccca tagtgaaagc ccccctgcgc ctgcaactat 7201 ggaaccggct tctaagtagt ttgacatagc tacagtaatt gtcgctttta atccaccttt 7261 cgcaccatcc gccataattt cctctcctcc aatatttagt gtccaataaa atacgcattt 7321 gctccatcca tccataaagg ttgaatggat ggagatgact attaaaactc actctaagtg 7381 aaatacttca tctagattaa tagatactgg actattatca ggattggtct tcattattgg 7441 tttcatgtac ttccaccatt tctgacatat ttcggtttct gccatttgct cccacaattt 7501 ttcatcttca atttctaaat aagcaaataa tctccctgtt tctttatcga gaaaaatcga 7561 atagttgtgt gcaccatggg ctttaagttc tgttaccatc tctggccaaa tttcatcgtg 7621 acggcgctta tattcttcat aactatcttt atttacaaac atgatacttg cttttctaat 7681 catcttaatt cacctctgta ttctttatag attcatcatt ttttggtgtt caaaatccct 7741 tgtctcggta caaccccaaa agcatctgcc aattctagta attgttggtc cgtaatggct 7801 tgttttaccc caccttgtgc acatacaatt gtatatactt gtgcagcttt ttcagccgtt 7861 tcaattaaac cgaatgcctc gtccattgta gtgccagcac caaatactcc atggtgaggc 7921 cacaccacta agcgaacatc cttcattttc gctgccgtcg cttttccaat tgcgtcagtt 7981 cctggaacca tccatggaat gattccaaca ccctctggaa atacaacgat acattctgta 8041 cacatttgcc ataatgtttt tgtaaatgcc ttttcatcca agctatgagt aaatgtcatc 8101 ccaagaatat gcgttgcatg gcaatgaatg attacacggt gattaggatc ggctttcaag 8161 cgttcgatat ggctcataaa atgtgtagga agttcacttg tcggtcctcc tccatcctca 8221 aacccccata aaacatcaac cgctttgcca tcctcggtta cccgaatgac accaaggttt 8281 tctgccggct tatccatcac atttttgaaa tatttaccgg aaccagtgac aataaaatac 8341 tttcctgcta gcgcagaagc atcaaaatgt attggcattg tacgtttaac atggtttata 8401 tctaaaaaag ggattacttc ttcttctttt agtaaataac tgatatttcc accgttacgt 8461 tcatcccaac ctaaacgata taaatttgcc gtggttttca tcatttcttg tgtaaactcc 8521 gctgttaaaa tatctaattt tcctgtcatt ttctctccac ctaaattctt tttagtaaca 8581 cttctttttc ataatttttc acttcagcca accattcctc acgaacaggc acaccttggg 8641 aagcacaata gtaatcccaa acagctccga aaggatagga tttgaattct tctcttaatg 8701 ccaaacgaga ggtatagtca ccttttaatt ccatttcttt taacagttct ataggttcta 8761 aaaaggcgcg aagcagtgct ttaagcatac tgcgtgctcc aatgacccaa gcagcaacgc 8821 gattgatgct accgtcaaag aaatcaagtc caatatacgt tttttcaagt aaattattca 8881 caaccaattc ccgtgcgatt tcctgcaatt catcatccat aatgactaca tggtcactat 8941 cccaacgaac aggacgactt acatgtagca acattccatt gctgtacaaa gaaagagcag 9001 atagtttatt tgaaacggtt tccgttggat ggaaatggcc catatccaag caaatgagtt 9061 tgttacgagt cagtgcatag cctatataaa attcatggga acctacaaca taactttctg 9121 aaccaattcc aaacagctta ctttcaaccg catctaagtt aaatttagga tcgatttcct 9181 cttcaaaaat ttcatccaat gcctcttcca gacgctttct tggtgccaag cgatccactg 9241 gaatatcttt gtatccatca ggaatccaaa tattagttac acatgtttgc ccggtttcct 9301 taccgaaata ttcgccgatt ttacgggaac gtttacaatg ttcaatccaa aaatcacgaa 9361 tttccttatt aggatggctt aatgtaaacc catcatctgc ttttggatgg gaaaaacatg 9421 ttggattgaa atcaagacct aacccctgtt cttttgccca ttctacccat ttttgataat 9481 ggcgcggctc gatctcatca aaatcaattt tttcatctgt atctacataa atggcatgca 9541 aatttaactt atgttttcca ggaattaaag aaaaggcttt ttctaaatct tgacgaagtt 9601 catctggagt tctagcagca cctggataat ttccggtaac cgcaattcct cctgttaacg 9661 cttggtcttt atttataaac ccgcgaacat catcaccttg ccaacaatgt aaagaaatct 9721 tgatattttt taattgatct agtactcggt ctgtatcaat accgtatttg gcatacgcct 9781 ttttggctaa ttcataagct tcctgtactt ccgacgtgat catataaaac gacctcctta 9841 aatttttgaa taatagcttg gcgatttatt tcatttgggg tatatttttt aatttcaaat 9901 gaatctctta taagctggcg agctgcctct aaatctttca cttcttttgt cgcaatcatc 9961 tgcataatca ggtttccaat agcagttgct tcagtagggc cagcatagac gacttttcca 10021 ctcaaatctg ctgttagttg attcaagtgc tcattgtagg ctcctccgcc aacgatatgc 10081 agctgatcaa tggtttttcc ggtgatctct tctaattctt gtattgcaat tgcataaata 10141 attgctaaat tgttgtaaat acaatttgct aattcaccga cggtttcagg tactttttga 10201 ttggtttcct tgcaataggt ttgaatttca tcaatcatat tggcaggatt cataaaccgt 10261 tcatcattaa aattaatgaa ctgatggaac ccttttactt tcttagcctc ttccacaaat 10321 tgtgaaaaat catagtcttg ttctaaatgt cgtctaactt cttgaatgat ccacattcca 10381 atgatgtttt ttaagaagcg gattgtttga aaagcgcccc attcatttgt ataattgtgt 10441 tgtaacgcca attcgttcac aataggaaca gcgctttcaa ttcctaacaa agaccatgtt 10501 ccactgctta aataagccca attttctcca aaccctggag taccaatgac agcggatgcg 10561 gtatcatggg tcgcaacagt gataactttg caattcggaa gatcgaaaga agagaaccat 10621 tcttttttca acataccaag ctctgtacct ggttccacca gcctcgcaaa ttgctctctt 10681 ttcacggaaa ttaaatcaag tagctcgtca tcaaatgttc tgctatttaa atttaacaat 10741 tgcgtggtgg aagcgtttgt aacttcagtt acagctacac cggttaaaca gtaacctaag 10801 tagtccggaa ccattagtat ctgatttgtg ttttttagct tttcttgatc ttcttcatac 10861 aactgataaa ttgtattaaa aggtaaaaat tgaattcccg tttttttata aatcttttct 10921 tttgaaacta attttgttac tttttcaatc gtttgtttag ttcttccatc tcgataagaa 10981 acaacctctc gtaaacgctt acctttttga tccaataaga cgtaatcaac ggcccatgta 11041 tcaattccaa ccgtacattg gtcgtaaccc agggatttta ctacctgaag tccttttaaa 11101 atttcattta ataaatagtc aatatcccaa taacaagtgc catctttcac tgtaaatcca 11161 ttagaaaacc tgtgtatttc tttgattttt aatttattat ccttgatttc ccccaacact 11221 aaacgcccac tggatgcacc gatatccacc gccacataga tcaccgattt atctcctcct 11281 tcagctcatt acacgctact atgaatctag caaaacacaa aattggtgaa acgataacaa 11341 gaagatttca accttataaa atttctttaa acatagaaat tacttcctct ttcgtaggtt 11401 gaaatggatt acctggtgca cacgcatctt taagagcatt atttgctaat ttttccaaat 11461 ccacttcatc aacgccaagc tctgaaagtt tgcttggaat acctatttct ctcgataatg 11521 ctttaatcgc ttcaatgact tcttctgcac attgttcatc tgtttttcct gttacgtcaa 11581 ttcctgctgc ctttgcaatc gcacggaatt ttcttggatc ccgctttgca ttttcccgct 11641 ctacaatcgg cagaagcatt gcgttgcata caccgtgggg caaatcgtac attcctccaa 11701 gctgatgggc catagcatga accataccga ggcctgcatt gttaaaggca attccaacta 11761 gaaacatggc gtatgccatt tgttcacgcg cttcaatgtc gtgaccattt tttacggctc 11821 tagggaggta attaaaaata atttctattg ctgcaagcgc tgtcgcatcg gtaactgtat 11881 atgaacctgg agttacaacc gcttctattg catgtgtcag cgcatccata cctgtcgctg 11941 cagttaaagc agcaggttta tctaccatta attcgggatc attgacagaa atggtcacta 12001 aactattctt atctaccata accattttta cattacgttc ttcatctgtt ataacatagt 12061 tgattgtaaa ttcactggat gttccagctg ttgtatttac cgctacaatc ggaaccgatt 12121 tattttttgt tttgtttaca ccttcataat cgcggatatc gccgccgttt gttacataaa 12181 gtccaatcgc tttcgctgta tcctgtggcg agccacctcc aacggatact aaaaaatcac 12241 attcattctt tttaaaaaga tctgcaccag catatacgtt tttcgtagtt ggatttggtt 12301 tcacatcatc ataaacaacg tagttaacac ctatttcatc caataccgct aatacctttc 12361 cagcaatacc gcttttatgc agaaatttat cggttacaac caacgctttt ttaaaaccaa 12421 actctttaat aaacggacca actttcgcca aacaccctct tcccatcaaa ttcgtgcttg 12481 gcacataaaa aacatgcgca ttgctcattt tactacctcc attcgaatca agtatgttta 12541 tattttcaca aataatcata gatgtgggaa acaaagatta accaatacaa attactactt 12601 tcaattttta tttggccgaa tgaacaactg taatctttgt ttctttttat ctagcaaaca 12661 aaacatttac aattaaatag taaccgtata caccttttgt tgtcaacata aacaaacata 12721 tttattgttg ttttttattt tattttttat gtttttgtca aatttatttt tttgttttca 12781 tgttttatgt ttgttttata tttgttttaa aacacaattg tatttgagca aattctcata 12841 aaccatattt tttatataca taaacaaaaa aacacctatg aaggtgtttc tgaataatca 12901 cggtatcttc ccgcaatata gtaaatattc ttgatgtttg aaagctgatg tccgatttac 12961 gagcaagttt tgcatagaca gtaaaaagct cgtccccaaa atgcattgac tgcatcagcc 13021 gtctctgcct ttttatacat atccaattga attgcttttt aacgcttatt ccattgttaa 13081 tctttacaat cttcttttga tcttcagttt gcaaaggtta tcgaaatatc taaaacggcg 13141 taatttatcc gatagcaacg ctttagtcta ataaagcaac aacttgattt agcttttcca 13201 aagcgttagg tgctattttt agtgtcgaag ttgattctcc cgttcctcca taaataaacg 13261 gataacgaaa aagttcttta tctactatac aaggcaaaga aagacctact aacggaacac 13321 tgccaacagt gtatccagtt atctgttgga cttcttttgg agttgccatt tttaattgat 13381 tacatcccag aatttctgac acttcttcca aatttacacg ccctcgacct ccagaaataa 13441 tcatcgcaaa ataacctttt tctgacttaa gaaccaatgt aggtgctgtc tggcctattt 13501 caattccaaa ataatccgca ccttcctgcg ccgtatggat tggactttcg tggtgaatga 13561 cttcaaattg aacgtcattt tcttgcaaaa tgctttttaa attatccata aacgggtgtc 13621 ccccttttta aagtttcctc gaaataattt ttaccgcaac tgactttcca atatcttaat 13681 tcaacgtact aatcaaattc tcctttgtaa tataaagaac aagtataata tgcaagcata 13741 tatgatttca tctattttcc atccttatgt taagatacaa actctcatgt ctatatgatg 13801 gcaaacttat gcgtttatct agtattctta acaatccccc attccttttc ctacgactcc 13861 ctattatctt tgaagaaaaa tgattataaa atttcaaata ttttcctgat gaccaataat 13921 aaaagggaaa cagttgggga tacgtataca atccagctaa acactccacc cacgttaact 13981 ttgtaaacga cttatttatc acaggatttt atgccattat cgcgctatca tgatggttca 14041 ggcaaatggg cagtatgtat taatttaaaa tcatcttaat ttggaaagat aactcccttt 14101 gattccctct ttgccagcga ttcctgatcc tttgatctga ggaataaccg aaaccaacag 14161 cattcctccc gcaaccaggc atccccatcc gcatatccgt tctccggtga tttgggatcg 14221 cattctccaa taaccgctgt acatcgtatc agccaagaag ctccaaaatg ttatcagcaa 14281 tcgtttggtc tgtctggcgc attgccgcgg ctgtccgata cagcaatcct tccgcttcgt 14341 tcagcttttc ttcatagcgg cggagccaat gaatcagctc atccttgaga ctatcgatcg 14401 cagcagtgct aatgccagga atctccatgg ctaaagaagg cagtgtccaa gaaagtgaag 14461 tccgcgcatg acagcaggcg tcttctccat cggggatatg cttcgctact atttccagtt 14521 cttccggttt gacttgaatc ttatcattgc cgctcctcta tttcagcgat ttccctgctt 14581 atttcatgaa gaagaccgtc tgccgttgca gccatcattt gccgcaagct cacagatatc 14641 gtctcatgcg ctttccccag cttttttctg ccaatgcgga ttgtcctcaa cggacaagat 14701 ttttaaagca aaagcaaagt actcatcata gtcctcatct tctaattcca gcccattgtc 14761 tgtttctaaa tagtgtctaa taaaccttta atccgcaaac cacctttcca ctctattatc 14821 agtgcggaac atactcgcca tccgcgtggt aaaattcgcg agtgccatgt tgaaattcct 14881 cggtcgcttc ttcgttctgt ctttgatgtg tatagttgta ctgccagctg tttatttggt 14941 tccattggga taatgattta acacctcgat aaattcatcc attttcttcc tctccacttt 15001 acagcctttc cggcaatatg tgcaccgttc ctcgaataat ggatactgcc gttttcagct 15061 catatggatt gactcactac atccaaacat catcagccat ctttgttcag ataaaattgc 15121 aactttttcc cattttatta tccgttatta tctttaatat ttcttgagca attgccttag 15181 cttcttcttt actaattaat ttttctggaa tttcatagaa taacaacaaa tgttctttca 15241 ggctaacatc ttcaggactt aattcaactg ctcttttagc atggtataat gcacttgcgt 15301 aagcgtctgg taaatgacac aatgcagtgc ttaataactc tgaagctaag taatgataat 15361 ctgcagtttc attattattt atcaaataac agacaaacga atatgcactt atactctctt 15421 catcaaatcc taattcaagt acaacttgct ctaaagtatt tctatcttca ttctcaatat 15481 attcttttgc tttttgaaaa tcacccgatg ttattaattg ctttatcttt tccttcatag 15541 ttatttcacc cacgcatcat attattctta ttgttccatc aggtcgtttt ttgtatgtcg 15601 cctgtactaa atgtccatta gctattctaa ctctagaaga aacagatttg taaggtatat 15661 ttgaaaaagg aaacccaaat aatatgctaa tttacaacac tcccttcaga ttccatgttg 15721 ccatggacac ccatgcgtta aactaactgc tacttttgcc tttgcagtct gggctgggac 15781 tttcccctat agaccacact ccatggctga ccatactaga agagcctcaa ggaactcctt 15841 gaggctcaaa ggacttaatc aagtattttt tctaacactt tttccaaatt aagcgcatta 15901 tcactaagtt cgattaacat tgtatcctca tcatcagcag gttcgtaacc tattataact 15961 ttaggaatat tatatttcat ttttaatttc actagataat taactaactt ttcaaacctt 16021 gatttaactt cctttttatc acctatgaat atttcgcttt ctggaaagtt aaaaacgata 16081 tctccgcatt cctcgtcgaa ggaaaaaacg attaccacat tttttaatgt tattcccaat 16141 tgcaattgtt ctagaacaat attgcccgtt ccttttggtg ataatatctc tttcatattt 16201 ttcacttgag gaaattccat atcttttccc gaattaaaat cataaaaatg tgatgactta 16261 atgtttaagg tagataattt cagttcttca tgaattagag tttcaatttc ctctttccta 16321 aaatccaata atataatctc taagttttcc attatcgcta acccctttta ctggtcaata 16381 aagcccttaa aagttccatc aagatttaaa cgcaccccac gtccatcagg aagttttttc 16441 tcaaggaact ctatgtttat tgcaaaataa aaatacagag ttctgcaagg aaaacgtgca 16501 gagcttgatt gggtaaaaaa aaagcttgcc agctcctaaa attccctcta ctgttaaggt 16561 tgtgaagact aaaacagtgg aggtaaagaa aggatgctag caatgcctga aattcattat 16621 atcaaacatt taagggaaaa caaagatctg tcgatctcgg aaattgcgag aaagacaggg 16681 ctgaattgga gaactgtcaa gaaatatgcc gatggaaata ttggcggaca aaaaatcatg 16741 aaaaagaaac gggggatgat gtacgagcta ggatatgggg agatcatcga tgactggctg 16801 gaggaggacg cgaagctgcc acgaaaagag cgaagaacca atcgaaccat gtttgaacaa 16861 ctgcaaaaag agcatggttt tcccggttct taccgaactg tatgtgccta cattcaggaa 16921 cggaagccgc atctcaaggc agaaaaggaa aaacgatacg aacggctgga gcatcctccg 16981 ggggaagccc aagtcgattt tggcacgatg caagtagtga aggatggagc tcttgaagat 17041 aaaaagctct tgattttgag cttcccccat agtaatgctg gatttgctca tcctctcccg 17101 tcagaaaata gggaatgctt cttggaagga ttgaaacagt tatttcatca agcaggggga 17161 gtgccgaggc gtttaaggat ggacaatttg cccgctgccg tggtgacagt cgggaaagga 17221 gataaccgtc agtataccga agcgtttctg cgtttccaag cccactacgg gtttgaagta 17281 cagccgtgca atcccgccag tgggcatgaa aaagggaatg tggagaggaa agtatactac 17341 gtacgccatc gttgtttcgt tcccgcccct gtggtggaaa gcgatgaaca gctgaccgaa 17401 tggctacggg tcaaaatgat cgaagatcgt tctcgccttc actatgaaaa aggagtgcca 17461 attgaagagt tgtggaaaga agatcaaaaa gagctgaaag cattgccttt ggacgatctt 17521 ccgatcttct ctttggatac ggtgaaagta aacaaatacg gggagattac agtggatggg 17581 gaaaagtggg tgatccatca agctcgggtg aaccagtctc tcgtggtgca aaaagggtgg 17641 gatcgcttta tctgcctatc caatcaagga gaagtcgttt ttgaagctcc tcggccgtat 17701 atgaaccaga aacaggaaat cccttgggaa gagattttca acgattggga gaagaagcct 17761 cgatccgtga gttattcgcg attttttaag tacttgccag agaaggtgca aacatatttg 17821 accttccgta aggaagaggt caaacagcgc gttcggggag ttcgggaact cttaaaaagc 17881 catacattga aagaactgga tgaatggttg aacaaagagc aacgattcga cttggcccct 17941 catgagttaa aggtgttgtt agaggcgaaa caacaagctt atccggaaaa gtgggaagaa 18001 acttacaccc cttcggtgtt tgtcaattat gagacggatt tacaccttta tgaccaacgg 18061 ctgtgtccgt catgggaagg aggggcaaac cgggatgact cgggacatca aagagatttg 18121 taaagcgttg catttggcgt atattgccga tcgttttgag gaggtgccat acgaaacaaa 18181 agagcaattt ttgcgggatg tactggcttt ggaagtctca tcgcgtcaag aagcgaaacg 18241 gtcgaagctg atcaagaagg ctaaattccg ggagttaaag tggctgaaag actatgagtg 18301 gtccgatcac attcattggc cctccacaac gaccaaagag gagctttgcg accttgtgtt 18361 tttggagcgg agacagaacg tattgctttt gggatcgccc ggaaccggga aaacccattt 18421 agccacggct ttaggattga aggcatgcga gaaaggccat gaggtgcggt ttttccgagt 18481 ggctgatctc gttgcccaac tggaagaggc cttaaaaaac gggacactgc cccgtctgaa 18541 acggcaaatc gagacgtgcg aactattgat tctcgatgaa ctgggatatg tgccgtttca 18601 aaaacaaggg tcagaactgc tttttcacat catcgcggac tgttacgaac gaaaaagtgt 18661 catcgtgacc tcgaatttag agtttggaca gtggaaccgg gtatttgggg ataaccgtct 18721 caccgctgcg ttagtggacc gtctggtcca tcacgcccat atcattgcct ttacaggaga 18781 aagctatcgt ctaagacacg cgctttcttc tgtgaagaag atatcatcca attagcaatt 18841 cattggaaaa atcgagctgc aagcctatgt attttttact gcaattctct gcattttttg 18901 cttgcaaaaa acaactctat ccccctagaa ttttttactc ttttaaatcc acctgttccg 18961 ttcaatattt cttggagatg ttttaatgcc atttgattta tttgggcagg acctcctttt 19021 actttccccc aaatatgtgg atttcttcct gcatgtttct gtaaagcatg acctactacc 19081 gtttctccac cctttttatg tgcagtagct gtctgtatta ttttattctt atct //