LOCUS NC_014253:7 18547 bp DNA linear BCT 09-OCT-2011 DEFINITION Methanohalobium evestigatum Z-7303 chromosome, complete genome. ACCESSION NC_014253 SOURCE Methanohalobium evestigatum Z-7303 chromosome, complete genome. COMMENT locus start: 933261; locus end: 951807 FEATURES Location/Qualifiers source 1..18547 /organism="Methanohalobium evestigatum Z-7303 chromosome, complete genome." gene 0..899 /gene="" /locus_tag="" /db_xref="933261..934160" CDS 0..899 /gene="" /product="beta-Ig-H3/fasciclin" /translation="MKIRYLVVLLTISMVLVSGCVQTEQQTEKNIVETAQDSDSFNTL VQAVQEAELVETLSGEGPFTVFAPTDEAFDKLPEGTLEELLNDKEKLRKVLTYHVVSG KYMANEVVEMDSIKTVQGENLSITANGGVMVNDANVTQTDIESSNGVIHAIDKVILPP SMTETEEMNIVETAISEGSFNTLVQAVQAAGLENTLRGDGPYTVFAPTDEAFEKLPEG TIENLLADEEQLTNVLTYHVVSGEYMANEVVEMESIETLQGSTLEITTTDSEVNIGNA TVVQTDIKCSNGVIHVIDEVLIP" gene complement(966..1241) /gene="" /locus_tag="" /db_xref="934227..934502" CDS complement(966..1241) /gene="" /product="hypothetical protein" /translation="MVIIKEIDISGLAKILAIANGTAGFIYGMFTTMAAFSGYLPGEG IFSILLGQWSIVMLPVFYGVSGYLIGLIAGYIYNKTVGSKGFEVKTK" gene 1458..2084 /gene="" /locus_tag="" /db_xref="934719..935345" CDS 1458..2084 /gene="" /product="hypothetical protein" /translation="MQNFIVKTYRYKDLPGNARRNAIHEYKEKIHKNGIVDGIIQNRL KQSLKRKGLPTKDINFSVGTRNEDFVHFYGPVAIKQFIDTFNQSLEDYPELNKLDDME QNAVFQIEPVSCVFCENQNNMTVKYDLLNSEIDGNKYHSELASLSRFIHQKSLETAGS LIDEAYRVASDQYNENVIENELIKWDYEFLENGAFINPALFDKISYMG" gene complement(2107..2226) /gene="" /locus_tag="" /db_xref="935368..935487" CDS complement(2107..2226) /gene="" /product="hypothetical protein" /translation="MGLKDKLLGFLSEKNVEEPRNKREHDMMKREKMRNQKQG" gene complement(2277..5939) /gene="" /locus_tag="" /db_xref="935538..939200" CDS complement(2277..5939) /gene="" /product="5-oxoprolinase" /translation="MKSENWQFWIDRGGTFTDIVAKKPNGKLVTHKLLSTNPEQYHDA AIQGIKDILNSSNDAPVPADKIDVIKMGTTVGTNALLERKGEKTVLVITKGFKDALRI GYQNRPDIFALEIIKPQQLYDCVIEVSGRYNADGQVINPLEFESVREKLKSAYDSGLN SIAIAFMHAYRYPSHEIKIAEIAKEIGFSQISMSHETSPLIKLISRAETTIVDAYLSP VLGRYINDIISMLKNNQTHEKDDETEKTRLMFMQSNGGLVNADSFQGKDCILSGPAGG VVGAVTTSSMAGFDKVISFDMGGTSTDVAHYRGEYERSFENIIGGIHLRSPMMQIHTI ASGGGSILHFDGERFRVGPDSAGSDPGPACYRRGGPLTVTDCNLMLNKINPEYFPHVF GPDANLPLDNQLVFEKFDELVDKITSYTGKNHTIEEVAEGFLDVAVENMANAIKKITT QRGYDIKEYALCCFGGAGGQHACKVADKLGINKIFIHPYAGVLSAYGIGLADQKEILE HAVEQQFDNKVLNNIKEIFLKLEKKGKNRLLRQGITSDKISSVPKIHLRYKGSDTTLM VDFVEGMDKESIISNFNKKHKQRFGFMSPEKTVVVEAVSMEVIGASDMKSEPVQKISK NNECVLTGNIEMFTDNKYHDTPVFRREDIKPGCRINGPAVIIENTSTIVIEPLWRAEI TEQNHIILTSTHQGFDGDFIGTEVDPVILEIFNNRFMSVAEQMGYTLQNTAHSVNIKE RRDFSCALFDKKGNLVANAPHIPVHIGSMSECVKSLINNKGTDMKKGDVYMLNSPYHG GTHLPDITVVTPVFDNDNNIYSYIASRGHHADIGGITPGSMPPDSKNIHEEGVFTDGI KLVDSGHFQENELFKWLNSGDYPARNPEQNVSDLHAQIAANEKGSQELKNLKDQYSLE TIKAYMEYVQDNAESEVCKVIGKLNNGIFSYQMDDGSIIKVQIKIDNENKSACIDFTG TSAQLFNNFNAPVSVCKAAILYVFRTMIESDIPLNDGCLRPIDIIVPKGSMLNPVYPA AVVAGNVETSQYIVDTLFGALGVMAASQGTMNNFTFGNKFHQYYETICGGSGAGAGFH GTDAVHTHMTNSKITDPEVLESRYPVILEEFSIRKNSGGCGMYKGGNGIIRKIRFLEE MDAAILSSHRKYPPFGLYGGIPGKCGSNRVIRKDGSVIEMGGKAKFRVYKDDVFTIET PGGGGYGYENTYISKQ" gene 6073..6492 /gene="" /locus_tag="" /db_xref="939334..939753" CDS 6073..6492 /gene="" /product="hypothetical protein" /translation="LNKYENRVIVGLFLIIMGTFLKWHDFMEYYRAYGPSGIGEVSQR VTGTVAGYDLIAGKVIFALSLILVVLIFLPKPALYHKRLLSAEFFLTSVITGLFVIGG LIPVFTPTQNIGPGIGLVVLFAGCIITLVYLKKDLNS" gene complement(6572..7612) /gene="" /locus_tag="" /db_xref="939833..940873" CDS complement(6572..7612) /gene="" /product="hypothetical protein" /translation="MILMMLILMLLVSGCTSQRSELTADQIKQTTIEKFETIDDYTYT MNITLPNNSTNYIVSEVSYKEPGKEKMTLHRYPENTDFTAVNNGSTIWIYNSEDNIAT RNPSGVTSLLELNPLNYRSFIKLINNSSPELLGSETLNGKQSYIMQFKLNTQQSIIPL SKTKTWIGKENYLPVKSELYINDTLIITAFFRDFKINENVSDSVFEYTPPENAIIMEP DNTLPQTINLDEAKSKVDFNIKIPTYLPKNYEMDYIQYVPEDSSVVIYYENDRYRDIL VVLQRPYMKPEKEPRIFGQENVTIGDDEGIYSNRTRTLEWNNKSVEYILQSEKLDKDE LIKIAESMEITQ" gene 7770..8018 /gene="" /locus_tag="" /db_xref="941031..941279" CDS 7770..8018 /gene="" /product="hypothetical protein" /translation="MVVPELSTIIIALIALAVIYFFFKTFKSLIVNAIVGLVILFGAN MLFGLGIAYTWLVILISAIGGALGALLIIVLHVFGIAF" gene complement(8023..9735) /gene="" /locus_tag="" /db_xref="941284..942996" CDS complement(8023..9735) /gene="" /product="signal transduction histidine kinase" /translation="VGLENDKIIVSNEWRKIHGCNNKVLTYNKLLQIVHPEDIPYMEN KLQDCLNNSSSYEIELRIIRKDTGEIRNVKTHGRIISDNDNNPIKMYGATQDITEWKK VHDELRKTADEFNYLFNNMNDAIFVQNLQGNFLNVNETAVKRLGYSRDELLSMAAQDV DYKYPSSGVKEKIDEILETGLLKFESVHITNNGTKIPVEVNSTLIHYRDKPAVLSIAR DITERKKAEEEKSVILNSTSEMIVFHNTEGKIKWCNKAFSKFTGFKQDELIGAYCYKL LHNKSDICDCCPISYIVKTGKHHEKITTFPNNVFNIKRDPVRDINGNIIGIISVSSDI TDKVRAEEKIKEYTNKLEEINTELENRVEEQTEQIRNAERMRELELHHRIKNNLQVIS SLINLQSEKFDDEEVYEAFIDTQNRIVSMSLVHQKLYQTSNLNSINFKDYIQDLLTHL TRLYGDNNITLDVDNIDNVYFDIDTIIPLAMLINELVSNSLKYAFSENESGEIKIMLH QIDNENYTLIVADNGRGIPEDIDIHDTDSLGLRLVNTLVDQIGGCLELERRKGSKFII EFGT" gene complement(9726..9875) /gene="" /locus_tag="" /db_xref="942987..943136" CDS complement(9726..9875) /gene="" /product="hypothetical protein" /translation="MWDSTEKASSDELQRYIEKLENENKELQKYKTLFKEAEYLSSVG SWEWD" gene complement(9976..10380) /gene="" /locus_tag="" /db_xref="943237..943641" CDS complement(9976..10380) /gene="" /product="hypothetical protein" /translation="MKFRVISTKSDIENIDKNDEYIHFAFRPSNTDIFNAISNNPDIK AIQIPSSYMKTLSKSMKMFFDIHNVSLIEGDIWGHRKDINEYYEVPDSVYKKLREMVN EGLSEDNIIEKMSKETRLDPDFIRFLLNHGNY" gene complement(10661..11386) /gene="" /locus_tag="" /db_xref="943922..944647" CDS complement(10661..11386) /gene="" /product="UBA/THIF-type NAD/FAD-binding protein" /translation="MISENEQNLYSRQIMMFGEEGQEKLKNSSVTITGSGGLGSPIAI YLAAAGVGKIRIIDHDTVALSNLNRQILHHHKDIGVLKVDSAKGKLNDLNPNIDIETF NETLSPDNIKNLIGKSHIVVDALDNYHTRFSLNEAAVQEQIPLVHGAVEGFHGQVTTI IPGETPCMRCFISKTPPKKTFPILGTTAGIIGTMQANEVIKYLTGSGKLLTGRLLLWD GFNSKTEEVPVNKNQYCEICATE" gene complement(11412..12126) /gene="" /locus_tag="" /db_xref="944673..945387" gene complement(12166..13326) /gene="" /locus_tag="" /db_xref="945427..946587" CDS complement(12166..13326) /gene="" /product="HtrA2 peptidase" /translation="MVDNKEHNVRSRILIVATVFFIAGLLVGGVSLALSLNPDENQNQ NQTQKNVHININKTINYSETYKELYNQVSDSVVSINIRESGLGSRISGQGSGFIYDSN RHILTNQHVIDGAENVEVVFSNGATQRANIVGSDKYSDIAVLRVDNIPEEENYSPSPL KLGNSSNIESGEFVMAIGNPFGLEGSITHGIVSATGRVLPTEEGFSIPNVIQTDAPLN PGNSGGPLLDLSGQIIGVNRAKSGDNVGFAIPANKARKVADSIIEKGEYEHAWIGISM VPVSYNAANYMDLNDTVSEGVMIVRVIDGGPAEKAGLEPGKQIVVNGEPTWVNGDIIL GMDNREIRNSDQLITYLDTKLPGDRIKLKIYRNENIKTVNVTLQDRPDNLLR" gene 13459..13698 /gene="" /locus_tag="" /db_xref="946720..946959" CDS 13459..13698 /gene="" /product="redox-active disulfide protein 2" /translation="MKIEVLGASGCSTCSKLKENIEKIVSEMGKSSEVEIVKIEDPVE IAKRGIMKTPVVVADGEVKFKGKVPSDDEIKEFLQ" gene 13933..15945 /gene="" /locus_tag="" /db_xref="947194..949206" gene complement(16113..16727) /gene="" /locus_tag="" /db_xref="949374..949988" CDS complement(16113..16727) /gene="" /product="4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein" /translation="MLKITPYLGILVLIVSIAGLWFPILGYFMLVVFAALLLISPFRG RWFCGNLCPRGSLNDFVVGKITKNKKIPETLKTLWLRVPVFAALMGFMGFRIMQTQGL INQIGMVFVVMCLVTTSIAVVLGISISPRTWCSFCPMGTAQRILGGNKYQLDIDEDRC ISCKKCDKSCPMHLKVHKNETKPDCIKCERCVNACPKGAIDFQD" gene complement(16762..17160) /gene="" /locus_tag="" /db_xref="950023..950421" CDS complement(16762..17160) /gene="" /product="transcriptional regulator TrmB" /translation="MIDFACKEFELDDVLKCALNLTKSELDIMNYFLRDTDRWVTTEN IATELKLDLSTVQKAVKKLHSNEVLKRSQNNLDNGGYVYIYRIYSRREIKNLIMDIVY TWVNRVDNELDQWIMGEQDKQYSKSEKAPI" gene 17377..18546 /gene="" /locus_tag="" /db_xref="950638..951807" CDS 17377..18546 /gene="" /product="major facilitator superfamily protein" /translation="MNSDRITLFILCLITFFGMSGSTLLGPVLPTIVEPLNTSREAVG LILAVYTLSTALFTLAIGSITDRINHKKILIPCLIVNGLSGMAAFFATDLTLLLFIRF IQGSAVAGMTPLAMTIIGGLYSGKQRIHAMGRRSMSIAIGAVSLPFIGGSMGIFGWNF PFLFYCLTIPIAIVAVFALPETNPEEFTGKATIELTDIKEALKDFRVSYTIFLSFAIA FLLYSVIIYVPFILEDSFDFTSQGAGIALSLRGASVIVVASQARKLSEIYSEHIVMSA GFGLLSAAIAGFPFVNTVSSTFLLLLLFGAGFGMIQPFLTTLIIQVSPSNIMGGIVSI FNTMKYIGQTAAPSVLGIILFYFNMDMIFIVSSIFGFIIALSVYLTKARFYETNQ" ORIGIN 1 atgaaaataa gatatttggt tgtattatta actatttcaa tggttttagt ttcaggatgt 61 gttcaaacag aacaacaaac agaaaagaat atagttgaaa ctgctcagga ttcagattca 121 tttaatacac ttgttcaggc tgttcaggaa gctgagttgg ttgaaacttt aagtggtgaa 181 ggtcctttca cagtttttgc accaacagat gaagcatttg ataaattacc agaaggcact 241 ctggaagaat tactcaatga taaagaaaaa ctgaggaaag tgctgacata tcatgtggtt 301 tctgggaaat acatggcaaa tgaagttgtg gaaatggata gcataaaaac agttcaaggt 361 gaaaatctat ctattactgc taatgggggt gtaatggtaa atgatgcaaa tgttacacag 421 actgatatag aaagtagtaa tggagttatc catgccatag ataaagttat attgccgcca 481 tcaatgaccg aaactgaaga gatgaatatt gtagaaaccg caatctcaga aggttctttt 541 aatacactgg tacaggcggt gcaagctgca ggtttagaaa atactctgag aggtgatgga 601 ccatacacag tatttgcacc aacagatgaa gcatttgaaa aacttcctga aggaacgatt 661 gaaaatttgc ttgcagatga agaacaatta acaaatgtat taacctacca cgtggtttct 721 ggggaataca tggcaaatga agttgtggaa atggaatcaa tagagactct tcagggcagt 781 acgcttgaaa taactacaac agatagtgaa gtgaatattg gtaatgctac cgttgtgcaa 841 accgatataa aatgcagtaa cggagttatt catgtaattg atgaggtttt aataccctaa 901 ttaaagcatg taaaattccg ctatctaaaa aataattttc agaaagggta tttccctttc 961 ttatttttac tttgttttaa cttcaaatcc tttagaccca acagttttgt tgtagatata 1021 tcctgcaatc aaacctatta gataccctga aacaccataa aaaacaggca gcattacaat 1081 agaccactgt cccaataaaa ttgaaaatat accttctccg ggtaaataac cactaaatgc 1141 ggccatagtt gtaaacatgc cataaatgaa tccagcagta ccgttggcta tagcaagtat 1201 ttttgctaac cctgagatgt cgatttcttt tattattacc attaatctcc ccccactcaa 1261 agttaagagc tttaatatgt aatattatag taattgacta tagatataat ttattagtta 1321 gctttttaca aaaccggtta caaatcagaa agtaatttat tgtcaaccgt taaactatta 1381 atactcgttt tctactgatt acttcagcta aacctctttg atactcctat attgacccgc 1441 cgtatatgag gaacccccat gcaaaacttt atagtaaaaa cctatagata taaagatctc 1501 cccgggaacg ccagaagaaa cgctatacac gagtataaag aaaaaatcca taaaaatggg 1561 attgtagatg gaataataca gaacaggtta aaacaatcat taaaaaggaa aggtcttcca 1621 accaaagata ttaatttctc agttggtaca cgaaatgaag attttgtgca tttttacgga 1681 cctgtagcaa ttaaacaatt tatagataca ttcaatcagt ctctggaaga ttatccagaa 1741 ctgaataaac ttgatgatat ggaacaaaat gcggttttcc agatagagcc tgtatcctgt 1801 gtattttgtg aaaaccagaa caatatgaca gtcaagtacg atttgctcaa ttctgaaatt 1861 gatggcaata aataccacag tgaacttgcg tcactttcaa gatttataca ccaaaaatcc 1921 cttgagactg ctggcagtct gatagatgaa gcatataggg tggcatcaga ccagtacaat 1981 gagaatgtga tagaaaacga gttaatcaaa tgggattatg aattcctgga aaacggtgcc 2041 tttataaacc cagcgttgtt tgacaaaata tcgtatatgg gatgaaccaa gaaagggttc 2101 atattaatta accctgtttc tggttcctca tcttttctct tttcatcata tcgtgttctc 2161 ttttgtttct cggctcttca acattttttt cgcttaaaaa tccaagtagt ttatctttaa 2221 gtcccatatt tttaagctcc gttccaaaca attttaaaaa cttatctgct atccaaatta 2281 ttgttttgat atatatgtgt tttcataacc gtaccctcct ccaccgggtg tctctattgt 2341 aaaaacatca tctttataca ctctgaattt tgcttttcca cccatttcta taactgagcc 2401 atctttgcga ataaccctgt tggatccgca tttaccggga ataccgccat acagcccaaa 2461 tggtgggtat tttctgtggc ttgacaatat ggcggcatcc atttcttcaa gaaaacgtat 2521 ttttcggatt attccatttc cacctttgta cataccacac ccaccgctgt ttttccttat 2581 tgaaaattct tccagtatta ccgggtatcg tgattccagt acttcagggt cggtgatttt 2641 tgaatttgtc atatgggtat gaactgcatc agttccgtga aatcctgctc ctgctcccga 2701 accaccacaa atcgtttcat aatattggtg gaacttgttt ccgaaagtaa aattgttcat 2761 tgttccctgt gaagcagcca taactcccag agctccaaaa agagtatcca ctatatattg 2821 ggaggtctct acattacccg caactacagc tgctggatat acaggattta acatcgaacc 2881 tttaggaaca atgatatcga ttggtctgag gcatccatca tttaacggaa tatctgattc 2941 aatcattgtt ctaaagacat aaagtatagc tgctttacac acagaaacgg gtgcattgaa 3001 gttgttgaac aattgtgctg atgtacctgt aaaatcaata caggcacttt tattctcatt 3061 gtcaattttt atctggactt ttataatact gccatcatcc atttgatagg aaaaaatccc 3121 attatttaac ttaccaatga ctttacacac ttctgattca gcattgtcct gaacatattc 3181 catgtaagct ttaatggtct caagtgaata ctggtctttt aagtttttca gttcctgaga 3241 acctttttca tttgctgcta tttgggcatg aaggtctgag acgttttgtt ctgggtttct 3301 tgcgggataa tcacccgaat tgagccattt aaacagttca ttttcttgga aatgtccgct 3361 atcaaccaat tttataccat cggtaaaaac accttcttca tggatatttt tactatcagg 3421 tggcattgat ccgggagtta tacctccaat gtctgcatga tgacctcttg aggcaatata 3481 agaatatatg ttgttgtcat tatcaaatac aggtgtaaca acggtaatat ctggcagatg 3541 tgttcccccg tgataaggag aattgagcat atatacatct cccttcttca tgtctgttcc 3601 tttattgttt atgagagatt ttacgcattc actcattgaa ccaatatgta caggtatatg 3661 gggagcattt gctacaagat tccctttttt atcaaaaagg gcgcaggaaa aatctcggcg 3721 ttcttttatg ttaacagaat gcgcagtatt ttgtaaagtg tatcccatct gttcagcaac 3781 agacataaag cggttgttga aaatttcaag tattaccgga tcaacttctg taccaataaa 3841 atcaccatca aaaccctgat gggtacttgt aagaattata tggttttgtt cagtaatttc 3901 ggctctccat aacggttcta ttacaatggt tgacgtgttt tcgataatta ccgcaggtcc 3961 gttaattcta catcccggtt ttatatcctc acgtctaaat accggggtat catgatattt 4021 attatcggta aacatttcta tgttcccagt gagtacacat tcattgtttt tgctaatttt 4081 ttgtaccggt tctgatttca tatcggaagc accgataacc tccattgaaa cagcttctac 4141 aacaactgtt ttttcaggag acatgaatcc aaaacgttgt ttgtgttttt tattaaaatt 4201 tgagattatg gattctttat ccatcccttc aacaaaatca accatgagtg tggtatctga 4261 acctttatat ctcaaatgta tttttggaac tgaacttatt ttatccgatg taataccctg 4321 tcttaaaagt cgatttttac cttttttttc aagttttaga aagatttctt taatgttgtt 4381 taatacttta ttatcgaatt gttgttctac agcatgttcc agtatttctt tctggtctgc 4441 aagccctata ccataggcag acaatacacc tgcatatgga tggataaaga ttttattgat 4501 acccagttta tctgctactt tgcaggcatg ttgaccacct gcaccaccaa aacagcataa 4561 agcatattct ttaatatcat atccgcgttg ggttgtgatt tttttgatag cgtttgccat 4621 gttttctaca gctacatcca gaaatccttc tgctacctct tcaattgtat gattcttacc 4681 tgtgtaagac gtgattttat caaccagttc atcgaacttc tcgaaaacca gctgattatc 4741 cagtggaaga tttgcatcag gtccgaagac gtgggggaaa tattcagggt ttattttgtt 4801 cagcattaga ttgcaatcgg taaccgtaag gggaccgccg cgccgataac atgcgggacc 4861 ggggtcggaa cctgcagagt caggaccaac tctaaaacgt tcaccatcaa agtgcaggat 4921 agagccaccg cctgatgcaa tagtatgtat ctgcatcatg ggtgaacgca gatgaatacc 4981 accaattata ttttcaaaac ttcgctcata ttcccctcta taatgagcca catcagtaga 5041 agtaccaccc atatcaaaac taatgacctt atcaaaacca gccatactgg atgtagttac 5101 agcacctaca acaccacctg caggaccgga aaggatacag tctttgccct gaaatgaatc 5161 tgcatttaca agtccgccat tggactgcat gaacatcaat ctggtttttt cggtttcatc 5221 atctttttca tgagtctgat tgtttttaag catagatatt atatcgttta tatatcttcc 5281 aagcacaggt gacagatagg catccactat tgtcgtttcg gcacggctta tcagttttat 5341 aagtgggctt gtttcatggg acattgatat ctgagaaaat ccgatttctt ttgcaatttc 5401 tgcaatttta atttcatgtg aagggtatcg gtaggcatgc atgaaagcaa tggcaataga 5461 gtttaatcca gaatcataag cggattttaa tttttcacgt actgattcaa attcaagtgg 5521 attaatcacc tgtccatctg cattatatct tccagaaact tctattacac aatcataaag 5581 ttgttgaggt tttataattt caagtgcaaa tatgtcaggt cggttctgat aaccgatacg 5641 taatgcatct ttaaaccctt tagtaattac aagaacagtt ttctcacctt ttctttctaa 5701 aagtgcattg gttcctacag ttgtacccat tttgataaca tcaattttat ctgcgggtac 5761 tggtgcatca ttggaagaat taagaatatc ttttattccc tgtatagctg catcatgata 5821 ttgttcagga tttgttgaaa gtaatttgtg agttaccagt ttcccattag gtttttttgc 5881 aacaatatct gtaaacgtac cgcctcggtc tatccaaaat tgccagttct cggatttcat 5941 gattaattca acaaagtctg ttgtgatata tcaactatat tatgcccatg tagaaatctt 6001 taatacaaat aaaactttca ttatattcaa tatataataa aaatattgaa aattatggtt 6061 gtgggtgaag agattgaata aatatgaaaa cagggtaatt gttggattat ttttgataat 6121 tatggggaca tttcttaaat ggcatgattt catggaatat tacagggctt atggtccatc 6181 tggtattggt gaagtaagcc aaagagttac agggaccgtt gcaggttatg atcttatagc 6241 aggcaaggtg atttttgcat tatcattgat acttgttgta ttgattttcc ttccaaaacc 6301 tgcattatat cataaaagac tactttcagc ggagtttttt cttacatctg taattactgg 6361 actttttgtt attggaggac tgattcctgt atttacacca acccaaaata taggaccggg 6421 aataggttta gtggttttat ttgcaggatg cattattaca cttgtttacc ttaaaaaaga 6481 tttgaatagt taaaaatctg ttatctaata cggttaatat aaggatattt tcagatattt 6541 atataagggt aataaaaata gtaaatgcag aattattggg taatttccat ggattctgca 6601 atttttatca gttcatcctt gtccagtttt tcagattgta atatgtattc cacacttttg 6661 ttattccatt ccaatgttct ggtacggttt gaatatatac cctcgtcatc accaattgta 6721 acgttttctt ggccaaaaat acgtggttct ttttcaggtt tcatgtatgg tctttgtaac 6781 actacaagga tatctctgta tctatcattt tcataataaa tcactacaga tgaatcttca 6841 ggaacatact ggatatagtc catttcataa ttttttggta aataagttgg tatttttata 6901 ttaaaatcaa ctttgctttt agcttcatca aggtttatag tttgtgggag tgtattatcc 6961 ggttccatga ttattgcatt ttcaggtggg gtatactcaa atacactatc tgaaacgttt 7021 tcattaattt taaaatctct gaaaaatgct gtaataataa gagtatcatt tatatataat 7081 tcggatttta ctggtagata gttctcctta ccaatccatg tttttgtttt acttagtggg 7141 atgatacttt gttgagtgtt cagcttaaat tgcattatat aggattgttt tccgttcaaa 7201 gtttcagaac caagtagttc aggactactg ttgtttatca attttataaa acttcgatag 7261 ttaaggggat tcaattccag aagacttgtt acaccggaag ggtttctggt tgctatatta 7321 tcttcagaat tgtatatcca tattgtagac ccgttattaa ctgctgtgaa atcagtgttt 7381 tcgggatatc tatgtaaggt cattttttct tttcccggtt ctttatatga gacttcggat 7441 actatataat tcgtgctatt attgggtaat gttatgttca tagtataagt ataatcatcg 7501 attgtttcaa atttttcaat agtggtttgt tttatttggt cagctgttaa ttcactcctc 7561 tgactagtac aacctgaaac taataacatt aatataagca tcattaatat cattattaaa 7621 ttcagtttag tcgtttaaac ccctccaatt aaataatact atttttaata taaacgcgtt 7681 atcctaagca gacatctcaa gatatgtatt aaaaatacag gaacgtttaa atatcatctc 7741 cgcgagaaaa ataagtaagg agtggatttt atggtagtgc cagaattatc aactataatt 7801 attgcattga tagcattagc agtgatttat ttctttttca agacgtttaa atcattgata 7861 gtaaacgcca ttgtaggact ggttatttta tttggtgcaa atatgttatt tgggcttggt 7921 attgcatata catggcttgt aattttgatt agtgcaatag gtggggcatt gggtgcatta 7981 cttattatag tcttgcacgt gtttggaatc gcgttttaag atattaagta ccaaattcga 8041 taatgaattt gcttcctttt cttctctcca gttctaagca gccccctatc tggtcgacga 8101 gggtgtttac aagcctgaga cccaatgaat cggtatcatg tatatctatg tcttcaggaa 8161 ttcctctacc gttatcagct acaatcaatg tataattttc attgtcaatt tggtggagca 8221 taatttttat ttcacctgat tcattttcag aaaacgcata ttttaacgaa ttggacacaa 8281 gctcgttgat aagcatggca agcggtatta tagtatcaat atcaaaatat acattatcta 8341 tattatctac atccagtgta atgttgttat cgccgtataa tctggtaaga tgggttaaaa 8401 gatcctggat ataatcttta aaattgatac tgttcaggtt gctggtttgg tatagttttt 8461 gatggacaag tgacattgaa acaatacggt tttgtgtatc tatgaacgct tcatacacct 8521 cttcatcatc gaatttttca gattggagat taataagact tgatataacc tgaaggttat 8581 ttttgattcg gtgatgcagc tccagctccc tcattctttc agcatttcta atttgttctg 8641 tctgttcttc tacacggttt tcaagttcgg tgttaatttc ttccagttta tttgtatatt 8701 cttttatttt ttcttcagcc cggactttat cggtgatatc acttgaaaca cttattatac 8761 cgattatatt gccattaata tctcttaccg ggtctctttt aatgttaaat acattgtttg 8821 gaaatgttgt gattttttca tgatgtttac cggtttttac aatataactt atagggcaac 8881 aatcacagat atctgattta ttatgaagca gtttataaca ataagcacca atcagttcat 8941 cctgtttgaa ccctgtaaac tttgaaaaag ctttattaca ccactttatc tttccttcag 9001 tattgtgaaa tacaatcatt tcggatgtag aattaaggat tacacttttt tcttcttctg 9061 ctttttttct ttctgtaata tctctggcta tactgagaac agcaggtttg tccctgtaat 9121 ggattaaggt agaattaact tctacaggaa tttttgtgcc attatttgtt atatgtacag 9181 attcaaattt taatagccca gtttcaagta tctcatctat cttttcttta acgccactgc 9241 tgggatattt gtaatcaaca tcctgtgcag ccattgaaag taattcatct ctggaatatc 9301 ccagtctttt aacagcagtc tcgttaacat tcaaaaaatt tccttgaagg ttttgaacaa 9361 aaatagcatc gttcatattg ttaaaaaggt aattgaattc gtctgctgtt tttctgagtt 9421 catcatgtac ctttttccat tcagtgatat cctgtgtggc tccgtacatt tttataggat 9481 tgttatcatt gtcacttatt attcttccat gtgttttgac attccttatt tcaccagtat 9541 cctttctgat tatacgaagt tcaatttcat aggatgatga attattcagg caatcctgca 9601 atttattttc catgtacggg atgtcttcag ggtgtacaat ctggagtaat ttattgtatg 9661 tcaaaacttt gttattgcat ccatgaattt tacgccattc atttgagaca atgattttat 9721 cattttctaa tcccactccc agctgcctac acttgacaga tattcggctt ctttgaaaag 9781 tgttttatat ttttgtaatt ccttgttctc gttttcaagt ttttcaatat acctctgtag 9841 ctcatctgat gatgcttttt cagtgctatc ccacattata ttcatcctta accagtatta 9901 accacccaat agtttgactt tggtaaaaaa gttatgtata gtgggatatt tctgtaattt 9961 tggtaaatgc acaaaatcag taatttccat gattgaggag aaatctgata aaatcagggt 10021 ctaatcttgt ttctttgctc attttttcaa taatgttatc ttctgataaa ccttcattaa 10081 ccatttctct taacttttta tatacactat caggcacttc ataatattcg tttatatctt 10141 ttctgtgtcc ccatatatct ccttctatga gtgaaacatt gtgtatgtca aaaaacattt 10201 tcatggattt tgagagcgtt ttcatgtatg agctgggtat ttggatagct ttaatatctg 10261 gattattgga aatagcatta aatatgtcag tatttgatgg tctaaaagca aaatggatat 10321 attcatcgtt tttatcaata ttttcaatat cgctttttgt acttataact ctgaacttca 10381 tgtaaatcac tctgtggttt taatttagtt aattgacaaa acttttcaac taaattttaa 10441 aatagtatgg tcaactattt aaaaattttg ttcactgcag aaaatataaa aatgaataac 10501 aaaacaaata atttgaattt ggtaaagttt tttaataaat caaaatcagt aaatggtaaa 10561 acccggaaca tggaaataat gtagctgaaa tcatttagat attatatcaa caatcattat 10621 tctatgttca cagatggtat attttggaaa acattcaata tttactcagt agcacatatt 10681 tcacaatatt ggtttttgtt taccggtact tcctctgttt tgctgttgaa tccatcccat 10741 aacaaaaggc gaccagttaa taatttaccg cttcccgtta gatattttat aacttcattt 10801 gcctgcatag taccaattat tcctgcagtt gttccaagaa taggaaatgt ttttttcggg 10861 ggagtttttg agatgaaaca tcgcatgcag ggtgtttctc cgggaataat agttgttacc 10921 tgtccatgaa aaccttccac cgcaccatgt accagtggaa tttgttcttg tactgcagct 10981 tcattgagtg aaaaacgtgt gtgataatta tccagtgcat ccacaacaat atgggattta 11041 ccaatcagat tttttatgtt gtcaggagaa agcgtctcat taaatgtttc tatatcgatg 11101 tttggattaa ggtcatttag ttttcctttt gcagaatcca cctttaaaac accaatatct 11161 ttatgatgat gaagtatctg gcggttcagg ttactcaatg ctacagtgtc atggtctata 11221 atcctgattt tacctactcc tgcagcagca aggtatatag ctattggaga accaagacct 11281 ccagaaccag ttatggtaac agacgaattt tttaatttct cttgcccctc ctcaccgaac 11341 atcataatct gccggctgta gagattttgc tcattttctg atatcattca ttataactct 11401 ccttttaacc attcaatcac ataggggtaa ctgttttttg taattgataa aaccattttc 11461 ataactaaaa agcagtgggt atactttaac ccctttttca atagcatgtt tataaatttt 11521 gtaaaattct ggatcgattc tcatatttgc tgtaaagcat tcagcatcgg gtctgaatac 11581 aagtattata attgcaccgg aatatccctg ttcaaccgct tttatcaact catttacatg 11641 ctttcccacg ggatgtaggg gcatctggaa ataatgcttt accgttattc tgaagggtgc 11701 atcctttaac ttctatccat gtcaatgaat cattttgttt tacaagaaaa tccagccggc 11761 tgtctccaaa tttttgttca ggtgttatac tatccacatt tccaagtggg ctgatttttt 11821 cattttcaat aaccagttct gctatttgtc tgtgatatac agaatttatc agaatccatt 11881 ttttatccgc ttttcctgca accatttccc agccggtctt tcgtttctga ccttctgctt 11941 ttcttagtag aactctattc ccgggatata gtatatcttc cagtcttcct gggtctttta 12001 tgtgtacttt ttcatttttg attggctctg ggctttttat gtcaactata ccaagaaacc 12061 tgttttctct ggatacaaaa attccttttg aatcccatga tatctgtaga actggtgtat 12121 tatccactta ttgcaccccg atataataaa aaaagttaga cctgttttac cgtaacaggt 12181 tatcaggtct gtcctggagt gtaacgttga ctgtttttat attttcattt ctgtagattt 12241 taagttttat tctgtcaccg ggtaattttg tatccagata tgttatcaac tggtcgctat 12301 ttctaatttc tctgttgtcc attcccagta ttatatcacc attgacccat gtaggttcac 12361 cgttaacaac aatttgttta cccggttcca atccggcttt ttcggctgga ccaccatcaa 12421 tcactcttac aatcataaca ccttctgata cagtatcgtt caggtccata taattggcag 12481 cattgtaact taccggtacc atactgatgc ctatccatgc gtgttcatat tctccttttt 12541 ctataatgga atctgcaact tttctggctt tgttagcagg aatggcaaaa ccgacattat 12601 caccactttt cgcccggttt acacctataa tctgaccaga aaggtcaagt agaggacctc 12661 cggaatttcc gggatttagt ggggcatcag tctggattac gttaggtata gaaaaccctt 12721 cttcagttgg cagtactctt ccggtagcac ttactatacc gtgggttata ctgccttcaa 12781 gaccaaacgg attaccaatc gccatgacaa attctccgga ttcgatattg gatgagttcc 12841 caagttttag tggagacggt gaataattct cttcttcagg gatattatcc actctcaaaa 12901 cagcgatatc cgagtattta tctgagccca ctatatttgc tctctgtgtt gctccgtttg 12961 aaaaaacaac ttctacattt tctgctccat cgattacatg ctgatttgtt aatatatgcc 13021 tgttagaatc ataaataaat cctgaacctt gacctgatat tcggctacca agaccgcttt 13081 ctcttatatt tatggatact actgaatctg aaacctgatt gtataattcc ttataggttt 13141 ctgagtaatt aattgtttta ttgatattta tatgaacatt tttttgtgtt tggttttgat 13201 tctggttttc atccggattc aatgaaagtg ccagtgaaac accaccaacc agtaaacctg 13261 ctatgaaaaa aacagttgcc acaataagta tccggcttct tacattatgc tctttattat 13321 ccaccattaa gttttaatta cgctattgat aaatttataa tttatgagat ttagcagtat 13381 tatttagtag gagataaatt tatgtaattc ttttacattt gtttcaataa atattgaaac 13441 aataatgagg tgataattga tgaagattga agtactggga gcaagcggat gttcaacctg 13501 ttctaaatta aaagaaaaca ttgaaaagat tgtatctgaa atgggaaaat cgagtgaagt 13561 tgaaattgta aaaattgaag accctgtaga aattgctaaa agaggtatta tgaaaacacc 13621 ggtagtagta gcagatggtg aagttaaatt caaaggcaaa gtaccttcag atgatgaaat 13681 taaagaattt ttacaataat ttaaagttaa atttatttta tttttgaatg atatagcaat 13741 accgcaattt tcaataaaat atttcacttt ttctactttt tccatttttg atattacgga 13801 taaattgaag tatcacaatt tcaccaattc atactgtttc actttaatat tacattatag 13861 attgcttata ttttagacat tatttgattt tttagaaaat gatgtttgat gaagtaactg 13921 gtttggtgat acagtggctg ataagagttt ttcaagttat agggattaca aaaataagta 13981 tacgagattg gtagggcttg aaagagaaga ggaaatgagg agacatcttg atgaaataaa 14041 aaacttgcat ccaaaagaaa gagaatcccg tggaagagct attcttaata tgaagggtag 14101 aaaccaagga aaaggacttg gtggtagata cattataaaa tttgtaaggg taaaaggcgg 14161 tcaattgcct gacacagaga tttctattgg cgactaggta atgataagca aaaacaaacc 14221 tcttgatccc aataatccgg aagccacggt aatagaaaaa accaattatt ccatttctgt 14281 atcatttaat agtaaacctc cggggatgat ttatggtaag ggtttaagaa tcgaccttta 14341 tgttaatgat ataacattcc aaaggatgct ggaatccata gaatactttg aaaatcctga 14401 aaatgacaaa tcccgtattc ataacatatt gattggaaat gcaagtccca tatttaatga 14461 aatgtcagag ccacaaatcc ataatgacaa tttaaattca tcccaaatca atgctgtaaa 14521 gaaatcgctt gagtcaaaag accttttttt agtacatggt ccaccaggaa ccggtaagac 14581 caccacacta atagaggtta ttgaacagca tatcgatagg ggtcataagg ttcttgcgac 14641 agctgattca aatgtggcag tggataatct ggtagatttt ttgaccagta aaaacaggaa 14701 agtggtaaga gtgggacatc ctgcacgtgt tacagaaaca ttgagacagc atacattgga 14761 tttccttgtt gaagataagg aaaaatacca gaaggctcag gaattgagga caaaagctaa 14821 tgaacttaat gaaaaacaga aagattatcc ctgctcaacc ggtagatgga gaagaggtct 14881 ttcaaatgat gcgataaaag accttgcaag aaaaggcaag ggttcaaggg gtattcctcc 14941 caaaaaaatg aaacaaatcg ccaaatggat tgaattacag gaacagataa attcaattat 15001 tgaaaaggcg aaaaaatttg aagatgaagc agtggatgaa ttgattcagg aaactgatgt 15061 agtttgtaca accaattcca ctgcagggag tgatttactg gaaaatgaat atttcgatga 15121 tgtggttata gatgaagcga cccaatccac agaaccatcc tgtttgatac ccatgaaaca 15181 tggaaataaa gtgatacttg caggggacca taaacagctc cctccaacaa tattaaatca 15241 ggaagcaaaa aaggaaggtc tggaagagac actttttgaa cggatgcttg aggttcacgg 15301 cacacagata aaacaaatgc tgaatatcca gtaccggatg aatactgaaa ttatgagttt 15361 tccaaataca catttttatg gaggagagtt gaaagctgca gacgaagtta aaaaccataa 15421 gcttgaacca tctgttttaa aggaatcacc cgatgagttg atagaaaaaa tctgtgattt 15481 taaaaatggc attacttttg tagatactaa tggcaatttc agagaaaatg cacctaaagg 15541 ttctacctca aaagaaaacc cagaagaagc aaaaattgtg aaaaatatag ttgacagaat 15601 actaaacaaa ggaataaatc ctgaaaacat agggataata tcaccctacg atgcccagat 15661 tgaccttctt aaaaacaaaa ttgattttag cggacttgag attaaaacag ttgatggttt 15721 ccagggaaga gaaaaagatg ctattattct gtcactggta aggtcaaacc aaaacgggga 15781 tatcgggttt ttaacggatt tgagaagatt gaatgtatcc cttacaagag ccagaaagaa 15841 gttgataata atcggtgatg gagatacact cggaaccgat agaacctaca atgagctcat 15901 gaattatata gcagaaaatg gaaactattt aaacatttca atttgagttc atgaataaaa 15961 aatagtaagg atagtggtga actatccgtt taatcatttc ttttgttctt ttcttaaaaa 16021 gagcagtatt gcaataccaa gcacaccaac cagaagaaca gggtttgcgg ttggaactcc 16081 tgtccagtgg tcatatctaa aagtcacacc ggtttagtct tgaaaatcta tagctccttt 16141 tgggcacgca ttaacgcatc gttcacattt aatgcagtct ggtttagttt catttttgtg 16201 gactttaaga tgcatggggc atgatttgtc acacttttta catgaaatac atctgtcttc 16261 atcaatatcc agttgatatt tgtttccacc aagtatcctc tgggcagttc ccatcggaca 16321 gaacgaacac catgttctgg ggcttatgga tattccaagt acaactgcaa ttgatgtagt 16381 aacaagacac atcactacaa agaccattcc aatctggtta ataagtccct gtgtctgcat 16441 aattctaaat cccataaatc ccataagggc tgcaaataca ggaactctta gccagagggt 16501 cttaagggtt tctggaatct ttttattctt tgtaatttta cctactacga aatcattaag 16561 gcttcctctc gggcacaggt ttccacaaaa ccatcgtcct ctgaatggac ttatcaaaag 16621 caatgcagca aacacaacca gcatgaaata tccaagaatc gggaaccata gtcctgcaat 16681 ggatacaatc agtaccagta ttccaagata cggagtaatt ttaagcataa tattcacctc 16741 ctgatagttt ttgattatta ttttatattg gggctttttc tgattttgaa tactgtttat 16801 cctgttctcc cattatccat tggtcgagtt cattatcaac tctattaacc caagtgtaga 16861 caatatccat tatcagattc tttatctccc tgcggctgta tattctgtat atgtatacat 16921 atccaccatt gtcgaggttg ttctgtgacc tcttgagaac ttcatttgaa tgcagttttt 16981 taacagcttt ctgaactgtt gacaggtcaa gtttcaattc agtagcaata ttttctgtag 17041 ttacccacct atcagtgtct ctcaggaaat aattcataat atcaagttcg gattttgtta 17101 aattcagtgc acatttaagg acatcatcca attcaaattc cttacatgca aagtctatca 17161 tttgtatacc tctttggtac ttctaattat catcagtact gctatataat atcagtatta 17221 tataaagagt ttcaagtact gataaaaaca tgataaaaat agaagtactg ttaatctgga 17281 cgataaatta ttttaaggct ttatcttttt aataaatccg ttgtggttct ttacataggt 17341 tacaacttca taatcgagca aattttgtat tcaaaatatg aattctgata gaataacact 17401 gtttatattg tgcctgatca cctttttcgg gatgtcgggc agtacattgc tggggcctgt 17461 tttaccgacc atagttgaac ctttaaacac cagccgtgaa gcagtaggtc tgattctggc 17521 tgtatataca ctatctactg cattgtttac attggcgata ggaagcatta cagatagaat 17581 taatcataaa aaaatactga taccctgcct gatagtaaat ggtttatctg ggatggcggc 17641 cttttttgca acagatttaa ccctgcttct ttttatacgg tttatccagg gttcagcagt 17701 tgcaggaatg actcctcttg ctatgactat cattggagga ctgtacagcg gtaaacaacg 17761 tattcatgct atgggtagaa gaagtatgtc catagcaata ggtgcggtat ctttaccatt 17821 tatcggggga agtatgggta tttttggatg gaatttccca tttctttttt actgcctgac 17881 cattccgata gctatagtag cagtatttgc acttcctgaa acaaatcctg aagaatttac 17941 aggcaaagca acgattgaac ttacagatat aaaagaagcc ttaaaagatt tcagggtttc 18001 ctacacgatt tttttaagtt ttgcaatagc ttttctgctt tactctgtaa ttatctatgt 18061 accttttata ctggaagaca gttttgattt tacatcacaa ggggcgggta tagctctcag 18121 tttacgcggt gcatcggtta tagtggtggc ttcacaggca agaaaattgt ctgaaatata 18181 ttccgaacat atagtgatgt cagcaggttt tggtctgcta agtgccgcta ttgcaggctt 18241 cccatttgta aatactgtgt catcaacatt tttattgtta ctcctttttg gagcaggatt 18301 tggaatgata cagccatttt taacaacatt aataattcag gtatcaccga gtaacataat 18361 gggaggaatt gtttcgattt ttaatacaat gaaatatatc ggtcaaactg ctgcaccctc 18421 agttctgggt ataatcctgt tttattttaa tatggatatg atttttattg tatccagtat 18481 tttcggattc atcattgcac tatcagtcta tttaacaaag gcaaggtttt atgaaacaaa 18541 ccagtaa //