LOCUS NC_013730:28 18457 bp DNA linear BCT 27-AUG-2011 DEFINITION Spirosoma linguale DSM 74, complete genome. ACCESSION NC_013730 SOURCE Spirosoma linguale DSM 74, complete genome. COMMENT locus start: 4399643; locus end: 4418099 FEATURES Location/Qualifiers source 1..18457 /organism="Spirosoma linguale DSM 74, complete genome." gene 0..1337 /gene="" /locus_tag="" /db_xref="4399643..4400980" CDS 0..1337 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MDRGIIEKKDVDSLARCRRQIEQVSGLGSGEGWTTADFDHLSEA ILATTGACLSVTTLKRVWGKVRYDSSPTTTTLNVLVQYLGYSNWHDFQDQAPQPNPVA DRTLPRRIDSSPVHTNSRRLGNRVIHYKVAICLIGLLTFMVVSDGQKPLSPQDFSFRS RPVTYGIPNSVVFDYDATASPTDSVFIQQSWDPTRRQLVSRTGHQHTSIYYHPGYFLA KLVVGKQIVREHDLLIRSDGWHIAVLQEPVPVYFKADEVIGQGKLSLPVSLIESSHVP MQPQPPVVRYRYIRELAGLRSDNFVFETRLRHDYRIGAAACQQTRLMIHGVGDMFFIP LSAKGCVSDLFLGVADHQVDGHNTDLSAFGVNLSKWVTLRCAVIQNKARIWVNGQLAY QAIIRTSPVDLVGITYEFTGTGSVDYCRFSRPTGELVFADSFDSRANPLTSKK" gene 1730..2719 /gene="" /locus_tag="" /db_xref="4401373..4402362" CDS 1730..2719 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MYAQYTQRAVGGYTVFTIPFEGDSVTFAVVAKPGELRARKPIFL FRQGSLPIPLFTINPKNNRPSLTELPISCYDHEAEYYSIMIAKPGVPIIANDAYLDTL FTTRNNPKPAMYPPQYQAHNYLDYYVRQTNAVLKFVLQQPWADVKRVVLAGGSEGYGV AIKTAYSNPEVTHLIAFSGFLDGRQQGIIREERMKGYTGEYTQEQAQQRVNGLQQQWS QICADSLNTSAKVGDPNRTHYSFSIDFRGYLLALTIPILIIYGTADIGATSNDVLPLE FAKRGKKNLDIKAYPNHDHTFYKLTYDGKGKIISKIYNGVAVEKDYFQWLHEH" gene 2744..3070 /gene="" /locus_tag="" /db_xref="4402387..4402713" CDS 2744..3070 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKPIVLLVTATFNGLGLTTLLGQTRYATADTAYVQAVEQALGHL EKGQCQPCLTAYQKAFKIAQKSALSTMRAALCAYQCQQPALAKTYIQQAVDINYSIAE DIWIDY" gene 3107..3697 /gene="" /locus_tag="" /db_xref="4402750..4403340" CDS 3107..3697 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKDLVQDIFEKKDAQLGINQSLKAQLQTIYTTDQQPRSRIDSLI RVYGQNSPQLQQLWQSIHREDSINLVKIEQIIRQYGYPGRRLVGAKLANTAWLIIQHS PLAIQEKYFPLIEQAANQEEMSKTNMALLIDRIRVYKGQNQLYGTQVKIESTGQKSFY PIEDQKNVNKRRSQVGLDSLEEYAKQFGFEYKPTGN" gene complement(3912..4832) /gene="" /locus_tag="" /db_xref="4403555..4404475" CDS complement(3912..4832) /gene="" /locus_tag="" /product="transcriptional regulator, AraC family" /translation="MKGEPKHKPRIYQSITEMQRAFGLPKPLHPLISLLDQNNVQITT EMLAPTFVMEFYNITYNESAGCKMRYGQTTYDFDEGGMFFSSPGQPLTGLQTAESSSG FTLLIHPDFLRNYPLDTKIKNYCFFSYSVTESLHLSDKEKKIITAMAKNIGDELETAI DDLSQDVLVAQLELMLNYSQRFYQRQFRTRKPINNALLEKVDRLLHTYFADETALLDG LPTVQFLSDQLQVSPRYLSDLLRSLTGQNTQQYIHQKLIEKAKQVLTISNLTVGEIAY QLGFEHPQSFSKLFKLKTNLSPLEFRQSFN" gene complement(4897..5703) /gene="" /locus_tag="" /db_xref="4404540..4405346" CDS complement(4897..5703) /gene="" /locus_tag="" /product="short-chain dehydrogenase/reductase SDR" /translation="MTKTIFITGASAGIGKATAKLFAAKGWHVIATMRKPENEKELNG LANVTLLPLDVTDRKQIKETAQKALVLGPVDVVFNNAGYALLGALEAISDEEIVRQME TNFLGVVRVTQAFIPYFREQKAGLFITTGSSAGLMGFPVSSMYDASKWALEGWSESLS FELNEFGIGIKTIEPGLVATEIADRAIFAAHPAYEAIMNRFTAMLAPDKAVSTAEQIA EVVYGAATDGTNTLRYVCGDDAKAWYAQRLAAGDEAFREGLKQMLAQVNV" gene complement(5916..6422) /gene="" /locus_tag="" /db_xref="4405559..4406065" CDS complement(5916..6422) /gene="" /locus_tag="" /product="GCN5-related N-acetyltransferase" /translation="MVNHNLTYRKANISDVPNIVGLTLSAYHDYQAVLAPADWARMET NLANKSLFVELLGKAAAFVCEKDNQLAGVIFLVPKGNPTTIFPADWSYIRLLGVDPTY RGLGIGRKLTQLCVQHAQATSEIGVALHTSEFMNAARQMYEALGFKQDKELAPMYGKR YWLYKLNF" gene 6812..7012 /gene="" /locus_tag="" /db_xref="4406455..4406655" CDS 6812..7012 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKNRHRSLLLFFVFTVLGGFNLSSLLGRPIFENMRGGDVAHLIG TIVMFGLAILCLKEYFFGRRSS" gene complement(7458..8393) /gene="" /locus_tag="" /db_xref="4407101..4408036" CDS complement(7458..8393) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKKILNQFGEKPLIRKEGGSLVQQEHIKKQISILAELESLIPPL LEDEYKQLEENIKNEGCREPLLVWQRSIEDGPQEEVQYLLIDGHNRYGICKRNSIDFK ISLREFTDIDAVKNFMIDNQLGRRNLTPEQMSYLRGQKYNALKKKLGRPGQVESLPLH PASKSAILPKKDPIRTEQVLADQFKVSPKTIRLDASYAKGLDKLAEPLKKEVLARKVK LNKGDVIALGDRQEPISPIATPNELIAVLKSDHSPQPAITRSSADGQNVNLQYKVSQV VSLVQKLSYPSESLVSTCEEMIQTLQSIVNELKRT" gene complement(8414..9367) /gene="" /locus_tag="" /db_xref="4408057..4409010" CDS complement(8414..9367) /gene="" /locus_tag="" /product="Cobyrinic acid ac-diamide synthase" /translation="MLTHQEAVQFLSKKPALSVSAIEKEAGLPVSTLPKALAGHRTLN QKHLTALEPVLLEYGLTEFRYRKARVISVVNHKGGVGKTTTTINLGRALALQTYKVLI VDMDSQGNLSQSVGVDNPEEQLYEALVHQKELPVLGVTENFDLVPSNLELAKYERDLT HSPSGSLRLKASLAPVLDKYDFILIDCPPALNIFTNSALIASTSALVVLEPETSAVKG MNNLFELIEEIRRFFNERLTIDGVLLTRVDRRLVLHKEIIQAVRQDLADFVVFQTEIR LSAALKESQYAQLDIFRYHPASPGAQDYQALANEYLGNLSY" gene 9735..9902 /gene="" /locus_tag="" /db_xref="4409378..4409545" CDS 9735..9902 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MATESKAPKTSAKKSSASGQLAPKSNMKAGLGLFKDKIVCESSA WEDDLRVTIKQ" gene 9899..10309 /gene="" /locus_tag="" /db_xref="4409542..4409952" CDS 9899..10309 /gene="" /locus_tag="" /product="PilT protein domain protein" /translation="MKKYLLDTHIIIWWLTDSPDLPASIRTILQNRTNEFYVSHESLR EIVIKAKLKRADFQLNGITIAEIANALRKTLGVKLLSSRVVYLAKLEALIPVHNDPFD HILISQAIVERLILISHDGNFPFYEAQGLKLLRA" gene 10411..10572 /gene="" /locus_tag="" /db_xref="4410054..4410215" CDS 10411..10572 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MMYLLQEMDFSLNDVSFEELVITISSLYYVIYGCNQLTIRCIFS KTLFISTHF" gene 10592..11164 /gene="" /locus_tag="" /db_xref="4410235..4410807" CDS 10592..11164 /gene="" /locus_tag="" /product="" /translation="MLFGYARVSTQDQNLALQLDDLKKAGCQKIFQEKVSSAKVRPQL QKMLEVLRQGDTLIVWKLDRLGRSLKELFTLINDFQAKEIGFRSLNDAIDTTTAQGRL VFNLFASLAEFERDMIRERTKAGLAAARARGRVGGRPKGLSAEAQAKARAVKSIYALK THTILEIGQLFHLSRATVYRYLAWKEAHKD" gene complement(11300..13732) /gene="" /locus_tag="" /db_xref="4410943..4413375" CDS complement(11300..13732) /gene="" /locus_tag="" /product="TonB-dependent receptor plug" /translation="MKIINILLVLMLQLCVHTGIAQNQAAGYSIRGIISDSASHNALT FITVNLIKSPATVLKVDYSKADGSFSFAGLESGSYTLAVVGVGYKTTRITVELPDSSQ KAGDLGNIPLMPDLVGLKEVVVKASKQIVKQEIDRITYDMQADPENKVFNALEMMRKV PLLSVDADNNVYLKGNADFRILINGKPSSMMERNYRDILRSMPASSIERIEVITTPPA KYDAEGLAGIINIITRKPVDNGYSGTVNVSERFPVGGPGVGGTVSAKFNKLGMTLMTG GNQYRIPSIRTMSERATRGQDPTYLTQNGTNRSTNYSGYLGYEISYEFDTLNLISAQF NINGSQARGFVSQNSLLMADSGLLEQYGLANTSRDLGRGMDAAFNYQRSAKVNKNQLL TFSYRYFGYSNNQKGQIDITERINVNLPDYRQVNNQQFSEQTLQVDYVYPIKKLNVEA GLKAIMRDNRSDFQFESFVTAANAFDPDPFRSNRFTNTQNVFGAYNTYQYTFKKWGLK AGARIEQTFVKADFVSTGSRVNQNYVNVIPSLSINRKLKNNAGFNFGYTQRIQRPGIY QLNPFVDRSNPSFERSGNPVLRPAFVNDFQLGFSTSKKVSLNIGLGYTHLRDMIMAVA VFNPQTNITRLTFGNTGRARLFMLMLNSNYSINKNWNLSLNSRVAHGRVFGVVDGQAV SNQGFMYQANLSTGYKLAKGWRVNGNLNVVGPNINIQGTTNSIVSSSLSVSKDMFNYK LALSAAVNNPFTQFRNAYRETFGPNFNQVDLRRDYFRSFTVSLNYKFGKLKEAIKKNK RGIRNDDVQTDN" gene complement(13916..14260) /gene="" /locus_tag="" /db_xref="4413559..4413903" CDS complement(13916..14260) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MSGDDIKHILIALGAFAGIFGIVYVFLMTRSRERMAMIERGVDA SIFSGNNAGSSTLKFGMLFVGIAIGIIGGHVLHDYYGFFKGTSFLAMIFLFGGLSLIL NFVIEQRWARKK" gene 14451..15002 /gene="" /locus_tag="" /db_xref="4414094..4414645" CDS 14451..15002 /gene="" /locus_tag="" /product="RNA polymerase, sigma-24 subunit, ECF subfamily" /translation="VKQPEDQVYIDKVRNGDSASYAFLVDRYKHMAYTIALRVMGNAE DAEDAAQDGFVKAYQQIHQFEGKSKFSTWLYTIVYRVAITRLEQQRVTTVPIHEEMTD AYTLQDYTSQLEHLQVSQQQNYIKEAIGRLPTTEGLLITLYYLDEKSIREIEVITGLS ASNIKVKLFRARKVLEDQLRFLL" gene 15037..15525 /gene="" /locus_tag="" /db_xref="4414680..4415168" CDS 15037..15525 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MEDEKEDRFRRLIQKVGPDNPGADFTSAIMKQVQAESELDLANE AALIQLLQAHPLVEKPSAAFSRRVMNQIRVSQPKLVEPIIRPWVWYMIAASLIMIIFF CILFLPSGPGQSASSDLNRFLSGIEGTLDTLPISYPLTIFAVSILMVSDYFLRRNLTV NV" gene 15956..16378 /gene="" /locus_tag="" /db_xref="4415599..4416021" CDS 15956..16378 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MSEGEKKLLASREEQRIGETEFYKSFPLKRYSEITHITSEIDKA IAEKDSVALDLLTYLVLHYLPSDSRYVELLNELLLASYHHKHQEVAKRLQKLKSPCRV VLPFRTKTVTWGYSTLVRSDVNRSADAGQPSPKRIFHE" gene complement(16407..16754) /gene="" /locus_tag="" /db_xref="4416050..4416397" CDS complement(16407..16754) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MDIPFDTEWSDEARLTFDRLPVDVQAGLIKQLPELVKNYADLYR RRPAESVCVGTTSHMQVPGWSMWLRLETEYHEDEVGPVLFIHGFDELSGKEFEQSLSA AKSMPGRINPSNS" gene complement(16794..17126) /gene="" /locus_tag="" /db_xref="4416437..4416769" CDS complement(16794..17126) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MYTLGLIKTERPNVLINPVGHSTPQAVYEWLERFFNLIDFTLET PISQEAVEQVLQSGKVGRINTNGYQVALLFGKTDVIQDATTRYIHLMPRSDDDVDMSK IENLVIPD" gene complement(17218..17757) /gene="" /locus_tag="" /db_xref="4416861..4417400" CDS complement(17218..17757) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MNTFFDELNVDHILHFIRSYRRLEQMPLEDGFAELACVAKSNQP AEEKRLRQHFRNHWYSKERAFGRFYLNLPHYRQLYLLHQWDLVHYEDATYLWECERDG RFALMAQAPPLTRQLHALVLFFENHGINRQLTPTLELDNVPTEFDQRFGNSANWGEYI LSIDQPDGLLRELLHHGRL" gene complement(17821..18387) /gene="" /locus_tag="" /db_xref="4417464..4418030" CDS complement(17821..18387) /gene="" /locus_tag="" /product="Resolvase domain protein" /translation="MNKLFGYARVSTLDQNLDTQLDALQKVDCDEIFQDKITGISTSR PALDAMLSQLRSGDTVVVARFFRLGRSRDHLISMLGEFARKGIHFKALDLGVDSSTPG GKLVLQIFAALAEYDRESILEKTRAGQLLAKAKGKHIGRPVGLDAEKFAKVKKALDRG LSVAETVSLTGISMSSVKRYRKQILMTN" ORIGIN 1 atggacaggg gtattatcga aaaaaaggat gtggatagtt tagcccgttg ccgccgccaa 61 atcgagcagg tcagcggtct ggggagtggg gagggatgga cgacggcgga ctttgatcac 121 ttgagtgagg ccattctggc aaccaccggg gcttgcctaa gcgtaacgac gctcaagcga 181 gtatggggta aagttcgcta cgattcctcg cccaccacaa ccacgctaaa cgtactggtc 241 cagtatctgg gttattcaaa ctggcatgac ttccaggatc aggctcctca acccaacccg 301 gtagcggatc gaacgttgcc acgccgtatt gattcctcac ccgttcatac aaactcgcgt 361 cggctaggaa accgggtcat tcactataaa gtggcgattt gcttaatcgg tctactcact 421 tttatggtgg tatcggatgg acaaaaaccc ctttcgcctc aggatttctc cttccgtagc 481 cgcccggtca catatggaat tcccaactcg gtggtgttcg attacgatgc gacggcttca 541 ccgacagatt cggtgttcat tcaacagtct tgggacccca cccggcgtca gcttgtatcc 601 cgcacgggtc atcaacatac ctcgatctat taccatccag gttactttct agctaaactg 661 gtggtgggta aacaaatcgt tcgcgagcac gatctgctta tccgctcgga tggctggcat 721 atcgccgtct tacaagagcc agtgccagtc tacttcaagg cggatgaggt gatcgggcaa 781 ggaaaactca gcctgcccgt atcgctcatt gaatcgagtc acgtgccgat gcaaccccag 841 ccacccgtgg tacggtatcg ctacattcgc gagttagcgg ggttacgatc ggataatttt 901 gtgttcgaaa cccggctccg ccatgattac cggatcgggg ccgccgcttg tcagcagacg 961 cgcctgatga tccatggtgt tggcgatatg ttttttatac cgctgtcggc gaaaggttgc 1021 gtttctgatt tgtttctagg cgtagcggac caccaggtag atggacacaa tacagacctg 1081 tcggccttcg gggttaactt gtccaaatgg gttacgctgc gttgtgcggt tatccagaac 1141 aaggcacgca tttgggtgaa cgggcaactc gcttatcaag caattattcg gacgtcgccg 1201 gtcgatctgg tcgggattac gtacgaattt acggggacag ggtcggttga ttattgccgg 1261 ttcagccgcc cgacgggtga actcgtcttt gccgatagct ttgactcacg agccaaccca 1321 ctcaccagca aaaagtagtt tggcctggtc tagttgtaaa cggttgtcaa tgtcgatttc 1381 agtcgattaa atagttcctg aactatcggt aactaagcgg ttctgttcat ggatgaacca 1441 ccggcttatt gggcttccaa cagactttgg ttaacgatta ctaataccca gaagccattc 1501 atacacttaa tatcagataa tcctcctcag tgagacgcgg aagcattcat gtatccgctt 1561 caagaactgg gcttttggtg agacggttga tattcacttg ccctcattta acaaatctta 1621 acttggagac aaaagtctgg ccgtccacct ttgcttgacc actaagatcg gctaagcttg 1681 tgaagttctt cctgttttcc gcttgcctaa ttttctcggc aattaacagt atgtatgctc 1741 agtatacgca acgtgcggtt gggggctata ctgtctttac cattcccttc gaaggcgatt 1801 cggtcacatt tgccgtagtt gctaagccag gcgagctaag agccaggaag cctatttttt 1861 tgtttcggca aggctccctg cctattccct tgtttacaat caatcccaaa aataatcggc 1921 cttcgttaac ggagttaccg attagttgct acgatcatga agcagagtac tatagtatca 1981 tgattgcgaa gcccggtgtt ccaatcattg caaatgatgc ctatttagat acgttgttta 2041 cgactcgaaa caatccaaaa ccagctatgt atccacccca gtaccaggct cataattatc 2101 tggactacta tgtacgtcag acgaacgccg tcctgaaatt tgtgcttcag caaccttggg 2161 ccgatgttaa acgagtagtg ttggcgggtg gttcggaagg gtacggcgtg gctattaaga 2221 ccgcttactc caaccctgaa gtgactcact tgattgcttt ttcaggcttc ctggacggtc 2281 gccaacaagg cattatacga gaggagcgga tgaaagggta caccggagaa tatacccagg 2341 agcaggcgca gcaacgtgta aacggattac agcagcagtg gagccagatt tgtgctgact 2401 cattaaacac atcggctaaa gtgggtgatc ccaatcggac gcactattcg ttctcgattg 2461 actttagagg gtacctgctg gccttgacga tacccatttt aatcatttat ggtacggccg 2521 atataggggc tacctccaat gatgttttac cgcttgaatt tgctaagcga ggtaagaaaa 2581 acttagacat taaagcttat cctaatcacg atcacacctt ttacaaacta acttatgatg 2641 gtaaaggcaa aatcattagt aaaatttata acggggttgc cgttgaaaaa gattattttc 2701 agtggttaca cgagcactag ccagatcgct tttccaaaca ttgtatgaaa ccaattgtcc 2761 tgctggtaac ggctactttt aatgggttag ggcttaccac tctattgggt caaaccaggt 2821 atgctactgc ggacacggcg tatgtccaag cggtcgaaca agccttaggt catcttgaaa 2881 aagggcagtg tcagccatgt ttaaccgcct atcaaaaggc tttcaaaatt gcccagaaaa 2941 gtgcccttag tacgatgaga gcggcacttt gtgcctatca gtgtcagcag cccgcgttag 3001 ccaaaaccta tattcagcaa gcggttgaca ttaattactc gatcgcagag gatatttgga 3061 ttgactatta gtctgcccct gagttcaccc cttttcgtac gtccacgatg aaggatttag 3121 tgcaggacat attcgaaaaa aaagatgctc agttagggat taatcagtcg ttgaaagctc 3181 aattacagac gatttatacc accgatcaac agccacgctc ccgtatcgat tcccttatac 3241 gtgtctacgg gcagaactcg cctcaactgc agcaactctg gcagtctatc caccgggaag 3301 attctatcaa cttggttaag atcgagcaga ttatccggca atatggatac cctggccgac 3361 gtttagtggg ggctaaacta gctaatacgg cttggttaat cattcagcat tcacccttag 3421 caattcagga gaagtacttc cctcttattg aacaagccgc caatcaggag gagatgtcaa 3481 aaacaaatat ggcgctattg attgatcgga ttcgcgtgta caaagggcag aatcagctat 3541 atggtactca agttaagatt gagtcaacag gtcagaaatc cttttatcca attgaagacc 3601 agaaaaacgt gaataaacgc cggtctcaag tcggattaga ttccttagaa gagtatgcca 3661 aacagtttgg ttttgagtat aagcccaccg gcaactagtg ccattggtta tcaattagta 3721 ctctctcaaa acgctccttg aagtgagatt aaccaagaat agttacaact acaaatcgca 3781 tcctccgcgg ctgcggttta aaaccaacga ttggcttaaa gaggctgaat aaatgcgtag 3841 gctacgaata ccgtttgacg gatttaaagg tgtaattggt ttttaattca atcgcggcaa 3901 acgcgaacgc ggtcaattaa acgactgccg gaattccagc ggagatagat tcgtttttaa 3961 tttaaataat ttgctgaatg actgcgggtg ttcaaatccc aactgatacg cgatttcgcc 4021 tacagtcagg ttgctgatcg tcagcacttg tttagctttc tcgatgagtt tttggtgaat 4081 gtattgctgc gtgttctgcc cggtgagcga ccgcaacagg tcgcttaaat agcggggcga 4141 aacctgtaat tggtccgaaa ggaattgaac cgttggcaac ccgtccagca aggcagtctc 4201 atcggcaaaa taggtatgca gcaacctatc gaccttttcc agcaacgcat tattgatcgg 4261 tttacgggtt ctaaactggc gttgatagaa tcgctgactg tagttcagca tgagctccaa 4321 ctgcgctact aatacatcct gactgaggtc gtcgatggct gtttccagct cgtcgccaat 4381 attcttcgcc atcgcggtaa taatcttttt ttctttatcc gacaggtgta gcgattcagt 4441 aaccgaataa gagaaaaagc agtaattttt gatcttggta tccaacgggt agttccgtag 4501 aaaatcggga tgtatcagca acgtgaagcc tgagctggac tccgcggttt gaaggcctgt 4561 taacggctgc ccgggtgatg aaaaaaacat accgccttca tcaaaatcat acgtagtttg 4621 cccgtatcgc attttgcaac ccgccgattc gttgtaggta atgttgtaaa actccataac 4681 aaaggtaggt gccagcatct cagtggtgat ctgtacgttg ttttggtcca gtaggctgat 4741 tagcggatgc agtggtttcg gtaaaccaaa agcccgttgc atttcggtaa tagactggta 4801 gatacgtggt ttgtgttttg gttccccttt catggttttc ttaataaatg ccggtacatt 4861 gtgttaacac agtgtaccgg caaagcaatt cctaaaatta cacgtttact tgggcaagca 4921 tttgcttcaa cccttctctg aaagcctcat cacctgcggc aaggcgctgg gcataccagg 4981 cttttgcatc gtcgccacat acatagcgta gggtatttgt gccatccgta gccgctccat 5041 acaccacttc ggcaatttgc tcggccgtag acaccgcttt atcgggcgcc agcatagccg 5101 taaatcgatt cattatcgct tcgtaggctg ggtgagcggc aaaaatggct ctatcggcta 5161 tttcagtagc caccaggcca ggctctatgg tcttaatgcc aatgccgaac tcgttcaact 5221 caaatgacag actttcgctc cagccctcca gcgcccattt gctggcgtcg tacatggagc 5281 tgacgggaaa acccatcaaa ccggccgaag acccagtggt gataaataac ccggctttct 5341 gctcccggaa gtaaggaata aacgcctgcg tcacccgaac tacgcccagg aaattggttt 5401 ccatctgccg aacgatctct tcatcgctga tggcttccag ggcacccagc aacgcatagc 5461 cggcattatt aaatactaca tcgacaggtc ccagcaccag cgccttctgt gctgtttctt 5521 taatctgttt cctatccgtt acgtccaatg ggagcagcgt gacattggcc aacccattaa 5581 gttctttttc gttttctggt ttacgcatgg tagcaatcac atgccagcct ttggccgcaa 5641 acagttttgc cgttgcctta cctattccag ctgaagcgcc cgtaataaaa atagtctttg 5701 tcattttttc tcgtgtattt tcgagtgaca aagctcctgc gctaacgctg accggctgta 5761 gtgaaagtgg tatatcttgt agtcaaaatg gtaaagaact cgttcccaat tattttttta 5821 cgatgttcta ttccccactc agttaggtca cgcggttttt ttatgcaccc acttataaaa 5881 gcccattctc aattaatgct cctaacaaga aatggactaa aagtttagct tatagagcca 5941 atagcgtttc ccatacatgg gggccaactc tttgtcttgt ttgaagccta gtgcttcata 6001 catctgacga gcggcattca tgaattcgct ggtgtgcaga gccactccga tttcgctagt 6061 ggcctgagca tgctggacac aaagctgggt caattttctg ccgatgccca agcctcgata 6121 cgtaggatct actcctagta gacggatata actccaatcg gcgggaaaaa tagtggtagg 6181 gttgcccttc ggcaccaaga agatgacacc ggctaactgg ttatcttttt cacaaacaaa 6241 ggcagcggct ttgcccagta gctcgacaaa caggctctta ttggctagat tggtttccat 6301 cctggcccaa tccgctgggg ctagaaccgc ttgataatcg tgataggcac ttagtgtcaa 6361 cccaacgatg ttgggaacgt cggaaatatt tgccttacgg tacgtcaaat tatgattgac 6421 catctttcgt actatccaag agctaacggg atagccaaag tacgaaaata atagataagc 6481 atttatgtgc tgtgcatctc tttaaaggct cccaactgag atatcaaatg ttgctctgaa 6541 aaggcgttta aatcaacagt tccgtaaggc tctgtaaccg ggaagagggg ataaacctaa 6601 aaagatggta gcgatggccg accatcaaat tgccagttgg ctaccgccat cactcggatg 6661 taaaacactt cttttacaaa cgataaattt aggagaaagc acttaactta gattatacag 6721 caagaatcac cgtagcctaa agagtttgca aagagtattg gtcaataacc tttattagca 6781 cttattcgtg cggccctaat acaccaaaaa ctatgaaaaa tcgacacagg tctcttctcc 6841 tgttcttcgt gtttacagtt cttggaggct tcaacctgtc aagcctgcta ggtcgtccca 6901 tttttgagaa catgcgaggg ggagatgttg cacacctgat cggcacaatt gtgatgttcg 6961 ggcttgccat cttgtgtctt aaggaatact ttttcggccg tcgctcatca tgaagactgg 7021 gcatccccag caatagtata gtagtacgtg tctgcgacgc agactccgct tcacgtattc 7081 gcacttatac aacaggtcgt acgctactgc tgacgttgga cagttattaa aaagttagta 7141 tctcattaaa ggctccctcc tgagacgccg aagcatttat tgatctgctt catagttggg 7201 gcgtttaatt ggccagcctc ttataaaaac tgtcaagtgg ccagcagtcg gtgcgccgac 7261 ccgggtctga ccgtcgccac tgcggtacta ttcgtagcat acgaagtaca cctctttaac 7321 atttggtgac tcattggtga gtattacttg taagtcttac agtccggcga cataagtctg 7381 acctaaataa gtagcaggta agtcatttag aaaaggtggt aaaatttacc accttttcta 7441 cccttctcag gccaagcgtc acgtacgctt aagttcgttc acaatcgact gtagtgtctg 7501 aatcatttct tcgcaggttg agacaagact ttccgaagga taagatagct tttgcaccaa 7561 cgagaccact tgactaactt tatattgtaa attcacgttc tgcccatcgg ctgatgatct 7621 tgtgatagct ggctgagggc tatgatcgga cttcagaact gcgattagtt cattgggggt 7681 cgcaattggg gatatcggct cctgacgatc accaagggca attacatcgc ctttattcag 7741 ttttactttc cgggctagca cttccttctt aagcggctcc gccagcttat cgagcccttt 7801 ggcgtaactc gcatccagtc ggatagtttt gggacttact ttaaactgat cagccaaaac 7861 ctgttcggta cgaatcgggt cttttttcgg tagaatagcg ctttttgacg cgggatgcag 7921 gggtaagctc tccacctggc caggcctacc caatttcttc ttgagtgcat tgtacttctg 7981 cccacgtaga tacgacattt gctcaggtgt aagattgcgc cgaccgagct ggttgtcaat 8041 cataaaattt tttaccgcat ctatatccgt aaactcccgc agcgatatct taaaatctat 8101 gctgtttcgc ttgcagatgc catagcggtt gtgtccatcg atcaacaggt actgtacttc 8161 ttcttgtggg ccgtcttcaa tagagcgttg ccaaacaagt agtggctccc gacaaccctc 8221 atttttgata ttctcttcta gctgcttgta ttcatcttcc agcagcggag gtatcaatga 8281 ttcaagctcg gcaaggatcg aaatctgctt tttaatgtgc tcttgctgaa ccagacttcc 8341 cccttccttg cggatcaacg gtttttcgcc aaactgattt aatattttct tcataggaag 8401 gtaccgtcag ggtgttagta agaaagattc cccaggtatt cgttagccag agcctggtaa 8461 tcctgagcgc cgggcgaagc cggatggtaa cgaaaaatgt cgagttgagc atattgtgac 8521 tccttcaaag ctgcacttaa ccgaatctcc gtctgaaata cgacaaagtc agccagatcc 8581 tgccgaacag cctgaatgat ctctttatgg agcacgagcc gtcggtcaac ccgggtgaga 8641 agaaccccat caatcgtcaa ccgttcgtta aaaaatcgac ggatctcctc aattaactca 8701 aacaaattat tcattccttt aacggccgag gtttcaggct ccagcacgac cagggctgat 8761 gttgacgcaa tcagcgccga attggtaaag atgttcagcg ccggcggaca gtcgatgaga 8821 atgaaatcgt atttatccaa caccggagcc agggaagcct tcaatcgcag tgagccgctg 8881 ggcgaatggg tcaaatcccg ttcgtacttc gccaattcga gattactcgg caccaaatcg 8941 aagttttcag taacccccaa aacaggtagt tctttttgat gaaccagcgc ttcgtaaagc 9001 tgctcttcgg gattgtcgac ccctacgctc tgggaaaggt ttccctgaga atccatatcc 9061 acaatcagca ccttgtaggt ctggagagcc agtgcccggc caaggtttat agtagtcgtg 9121 gttttaccaa cacctccttt gtggtttaca acggaaatta cccgggcctt cctgtatcgg 9181 aattccgtca gaccgtactc tagcaaaaca ggctcaaggg ctgtaagatg tttttgattt 9241 agcgtacggt ggccagctaa tgctttgggc agggtgctta ccggcagtcc agcttctttt 9301 tcaatagcgg aaacagagag agctggtttc ttgcttaaaa attggacggc ttcttgatga 9361 gtaagcataa gagtggtgta aaatatgtct caatattagg gcttatttag atgatagcaa 9421 gatatttgac taaaaataaa gacattttgt tagtgtatat ttcggttacc cttaattatg 9481 tcatcaaagt agttaggcta taatttacaa gtagaccgta tcctacggat ggcgtttgac 9541 agaaattaga aattgagtgt atcgcaaaaa cactcattaa tttgggccgc tctagttagt 9601 acgtcttggg tagacgtaca tttgtcaaaa catttgtctg agcttctggg gatggcccaa 9661 cctaaaaagc gccgatcttt gcaaaacttt acttcggtgt aaaaacgtta tatttgtcaa 9721 acaactctca atgtgatggc aacagaatca aaagccccca aaacctcggc caagaagtcg 9781 tcggccagtg gccagttggc tcccaagtca aatatgaagg cagggctagg cttatttaag 9841 gataaaatcg tctgcgagtc gtcggcttgg gaagatgacc tgcgagtgac gattaagcaa 9901 tgaagaaata tttactggat acacatatta ttatctggtg gctaaccgat tcaccagact 9961 taccagcctc catccgaacg attcttcaaa accgtaccaa tgaattctac gttagccatg 10021 aaagcctacg tgagattgtc atcaaggcta agctaaagcg ggctgatttc caattaaatg 10081 gtattactat tgcggaaatt gccaatgcgt tacgcaaaac gctgggtgtg aaactactct 10141 catcgcgggt cgtctaccta gcgaaattgg aagccctgat accggtacac aacgacccct 10201 tcgaccatat tctgattagc caggccattg ttgagcgttt gatcctaatt agccacgatg 10261 gcaattttcc cttctacgaa gcacaaggcc taaagctact aagagcttaa gttaaatatg 10321 ctactgcccg caatttgtag gtcactagct gaagaggcac ctattcaaca taatcgtctc 10381 actaaactgc ctaaattatt atgaaggata tatgatgtat ctgcttcaag aaatggactt 10441 ctccttaaac gatgtatctt ttgaagaact agttattact atttcttctc tctattacgt 10501 tatatatgga tgcaaccaac tgactattag gtgcatcttc tcgaaaacgc tctttatcag 10561 tacgcatttt tgagaccgtt tcgcctattt ttatgttatt tggctacgca cgcgtatcaa 10621 cgcaagatca gaatttagct ctacaattgg atgacctgaa aaaagcaggc tgtcaaaaaa 10681 tctttcaaga aaaagtgtct tcggcaaaag tacggccaca gcttcaaaaa atgctggagg 10741 ttttgcgaca aggcgacacc ctcatcgttt ggaagctgga tcgactaggc agatcactaa 10801 aagagctttt tacattgatc aatgactttc aagctaaaga aattggcttc cgaagtttga 10861 atgatgccat tgataccact acggctcaag gacgtttagt gtttaattta tttgcctcgc 10921 tggccgagtt cgaacgggat atgatccggg aacgtaccaa ggcgggtcta gcggcagctc 10981 gtgccagggg acgagtgggc ggccgtccga aaggactctc tgctgaagct caagcgaaag 11041 cacgggccgt gaagtctata tatgccctca agacgcatac tattttagag attggtcagt 11101 tgtttcacct aagccgagca acggtgtatc gatatctagc ttggaaggaa gcacacaaag 11161 attgagtagt gaaggacatt gcttcataaa acgggccttt aatggaacga cttgttttaa 11221 taactgtcaa cttctatgcg tcgcatacaa tgatatggta tccgtcttaa ttgcccttaa 11281 atcggactac ctcacgtaaa ctaattatcg gtttgtacat cgtcattccg gatgcctcgt 11341 ttatttttct tgatcgcttc ttttagcttg ccgaatttat agttcaggct aacagtaaag 11401 gaccgaaaat aatcgcgtcg aagatctact tggttgaagt tcggcccgaa cgtttcacga 11461 tatgcattcc ggaactgggt aaacggatta ttgacggctg ctgagagggc taatttgtag 11521 ttaaacatat ctttactcac gctcaacgag gaactcacta ttgaattagt agtaccctga 11581 atgttgatat tggggccaac tacgttcagg ttgccgttca cccgccagcc tttggccagt 11641 ttgtagcccg ttgacaagtt cgcttggtac ataaagccct gattagaaac cgcctgacca 11701 tcgaccacgc caaagaccct accatgggca acccgagagt tcaggcttaa attccagttc 11761 ttattaatcg aataattgct attcagcatc agcataaata accgcgctcg tcctgtatta 11821 ccaaacgtta agcgggtaat attggtctgg ggattgaaaa cggccaccgc catgatcatg 11881 tcccgtaagt gagtatagcc taaaccgatg tttagggaga ctttttttga cgtactgaag 11941 ccgagctgaa aatcatttac aaaagcgggc cgtaagaccg gattgccgct acgctcaaaa 12001 ctggggtttg agcgatccac aaacggattg agttggtaga taccaggacg ttgaatgcgc 12061 tgggtgtagc caaaattgaa accggcgttg tttttcaact ttcgattgat gctcagcgac 12121 ggaatgacat tgacgtaatt ctgatttact cttgaacccg tggatacaaa atccgctttt 12181 acaaaggttt gttcaatcct tgcccccgct tttagccccc attttttgaa tgtatattga 12241 tacgtgttat aagcaccgaa aacgttctgc gtattggtaa accgattgct tcggaatggg 12301 tccggatcaa aagcattcgc tgccgtgaca aatgattcaa actgaaaatc gcttcggtta 12361 tcacgcatga tggctttcaa tcccgcttcg acgttgagtt tttttatcgg atacacataa 12421 tccacctgga gggtttgctc cgagaattgc tgattgttga cctggcggta atcgggtagg 12481 ttaacgttga tccgttcggt gatgtctatc tggccctttt ggttattgct gtaaccaaaa 12541 taccggtagg aaaatgtaag cagctggttt ttgttcactt tagcacttcg ttgatagtta 12601 aaggcagcat ccatcccgcg accaagatca cgactggtgt tggccagccc atattgctca 12661 agaagcccgg agtcggccat caggagggag ttttgggaga caaaccctct agcctgactg 12721 ccattaatgt tgaactgcgc actaatcagg ttaagcgtgt caaattcgta actaatttcg 12781 tagcccaggt aaccgctata attagttgat cggttagtgc cgttttgggt aagataggtc 12841 gggtcctggc ctcgggtagc gcgttcggac atcgttcgga tacttggtat tcgatactgg 12901 ttgccccccg tcatcaaggt catccctagc ttattgaatt tggcggatac tgtgccacct 12961 acaccaggcc cgcccaccgg aaaacgctcg ctaacgttga cggtgccact atagccattg 13021 tcgacaggtt tacgggtaat gatgttgatg atgcccgcca gaccttccgc gtcatatttt 13081 gccggggggg tagtgatcac ttcaatccgt tcaatcgagg aggcaggcat gctccgcagg 13141 atgtcgcggt aatttcgttc catcatgctt gacggtttgc cgttaatcag aattctgaaa 13201 tcagcatttc cttttagata aacgttattg tccgcgtcca ccgacagcag gggcactttc 13261 cgcatcattt ccaaggcatt aaagaccttg ttttcaggat cggcctgcat atcgtacgtg 13321 atacggtcaa tttcctgctt tacaatctgt tttgacgctt ttacaaccac ttccttcagg 13381 cccaccaagt caggcatcag cggtatgttg cctaaatccc ctgctttttg actggaatcc 13441 ggcaactcca ccgtgattct ggtcgtcttg tagcctacac cgacaacagc cagcgtataa 13501 cttcccgatt ccaaccccgc aaacgaaaat gagccatccg ctttggaata atcgactttc 13561 agaacggtag ctgggctctt tatcagattt accgttatga aagtcaatgc gttatggctt 13621 gccgaatcgg aaatgattcc gcgaatcgaa tagcctgctg cttgattttg ggcgataccc 13681 gtgtgtacac acaactggag catcaaaacc aaaagtatgt ttataatttt catacgttta 13741 ataatcaatc gattgaaaaa ggcatggcga tcccagtaag agattcaggc tcttttagag 13801 aaaagcatag gaacagaaat ggaacagtta tcggtagtag ccaaccagaa tcaggaaaga 13861 agcagattgt ctggctttat gcgctgttaa aaagcaggag agaggttaag gcaggttcac 13921 tttttcctgg cccaacgctg ctcaataacg aagttgagga ttaagctaag ccccccgaat 13981 aaaaatatca tggccaagaa agaggtgcct ttaaagaatc cataataatc gtgcagcaca 14041 tgcccaccaa taatgccgat ggcaattcca acgaacagca tcccgaattt gagggtagac 14101 gaaccagcgt tattgcccga aaatatggac gcgtcgactc ctctctcgat catagccatc 14161 ctttcccggg aacgggtcat caggaataca tacacgattc cgaaaatgcc ggcaaatgca 14221 cccagggcta taagtatatg ttttatgtca tcaccactca tacagctgtt cgtttaatag 14281 tttttattga ctgattttgc cccatatgac agatgaaaca aaaatcgggt tacagttttc 14341 gataaaaatt tatgggtaaa aaaaattgag tcaagctgta acctcctttt gaaaacgaat 14401 gtctaactgg gcaaggcgcg taaatggact gccaaattaa cgaatcggct cgtgaagcaa 14461 ccggaagatc aggtctatat cgataaagtc agaaatggag actcggcttc ctatgcattt 14521 cttgttgatc ggtataagca tatggcctat acgattgcgc tgcgcgtaat ggggaatgct 14581 gaagatgctg aagacgctgc acaggatgga tttgtcaaag cctatcagca aatccaccag 14641 ttcgaaggga aatcgaagtt ttctacctgg ctctacacca ttgtttatcg ggtagccatt 14701 acgcgattag agcagcaacg ggtaaccacg gttcctatcc atgaggaaat gacggatgca 14761 tatacgttac aggattatac ttctcaactg gagcatctac aggtgtccca acagcagaac 14821 tatatcaaag aagccatcgg ccgattaccg acaacagaag gattattgat tacgttgtat 14881 taccttgatg aaaagtcaat ccgagaaatt gaagtgatta ccggcttatc ggcatccaac 14941 atcaaggtaa aattatttcg ggccagaaaa gtattggaag accagttacg ttttttattg 15001 taaatgaacc gattgtcgat ttgaactgcc tttatttatg gaggacgaaa aagaagatcg 15061 tttcagaagg ctgatccaga aagtgggacc cgacaacccg ggtgctgact ttaccagtgc 15121 catcatgaaa caggtacagg ccgaatcgga actggacttg gcaaacgaag ccgccctgat 15181 tcagcttcta caagcgcatc ccctggtcga gaaaccatcg gcggctttca gtcgtcgggt 15241 tatgaatcag atcagggttt cgcagccaaa gctggtggag cccatcattc gcccctgggt 15301 atggtacatg atagccgcat cactgataat gatcattttt ttctgtatac ttttccttcc 15361 ttccggtccc ggtcaatctg catcgtcgga cctgaatcgg tttctttccg gcatagaggg 15421 aaccctggac acccttccga ttagttaccc actgaccatt tttgccgtta gtattctgat 15481 ggtatcagat tattttctaa ggcggaattt aactgtaaat gtctaactgc taacgtttac 15541 gtctggcgtc tattcccgtt tagctaacca gtgtacaggc agcggcaact agaataagtc 15601 aagcgcatgc gaccgatggc gtttgagcga tagtaaaaat cagtgtctct caaaaggctc 15661 ccatctgaga cgcagaagca gttgtgtatc cgcttcaaga actgggtgtt taaagaaact 15721 gtacagtaag agcatatagc cgggaatgtg ggcaaacttg aaagggtgat gatgacggac 15781 ggccgtcaaa tttccagtca gtcttggcca acacctggcc caagactctt cttctattaa 15841 cgatcaattc aataaaaagc acttatatta tctgtataac agtgtataac aaaacgtcag 15901 ttttgtttaa cttttcgtcc aggtaaacat aacgtggatt atacaacaga gactacatga 15961 gcgaagggga gaaaaaacta ctagctagtc gagaagagca aagaataggt gaaacggaat 16021 tttataaatc gtttcccttg aagcgatatt cagagatcac tcatataacc agtgaaatag 16081 ataaagccat tgctgaaaaa gactcggtag cacttgatct gttaacctac ttggtactac 16141 actacttacc ttctgatagt aggtatgtcg aactcctaaa tgaactctta ttagctagct 16201 atcaccataa gcaccaagaa gtggctaaaa gattacagaa gctaaaaagc ccatgtaggg 16261 tagttttgcc gtttcgtaca aaaaccgtca cttggggtta ctcaacatta gtacgatcgg 16321 atgtcaaccg gtccgccgat gcgggccaac cgtcgccgaa gcgaatattc catgaataac 16381 ttatcagatt gactccgtca agataagtta ggaatttgat gggttaatcc gaccaggcat 16441 cgatttagca gccgataggg attgctcaaa ctctttaccc gacaactcat cgaacccatg 16501 aataaagaga acagggccta cttcatcttc atgatattcc gtttctaagc gtaaccacat 16561 actccagcct ggaacttgca tatgggacgt cgtaccgaca cagacacttt cggcaggtct 16621 tcgccgatac aaatcagcat agtttttaac cagctcaggt aactgcttga tcagccccgc 16681 ctgtacgtca actggcaagc gatcaaaggt cagtcgggct tcgtcagacc attctgtatc 16741 gaaagggatg tccattgttt aatgagaggc tagtaaatca aatctccagc tcaattagtc 16801 agggataacc aagttttcga tcttactcat gtctacgtca tcgtctgaac gaggcatcag 16861 atgaatatag cgagttgtgg catcctgaat gacgtccgtt tttccaaaga ggagcgccac 16921 ctggtagccg ttcgtattga ttcgccctac tttaccgctt tgcaacacct gctcaacagc 16981 ttcctgggaa atgggggttt ctaaggtaaa atcaatcaga ttgaaaaacc gctctaacca 17041 ctcataaacg gcttgagggg tggagtgtcc aaccggatta attaacacat tcggacgttc 17101 tgttttgatc aaaccaaggg tgtacataac tagagattaa gtgaatgact tgtggacaat 17161 ataggttatg acgctgaagg gtgaatggca aaactcaaaa ataaattgag cgatcagtct 17221 atagccttcc gtgatggagt agctctctaa gtaatccgtc cggctgatct attgacagaa 17281 tatactcacc ccaattggct gaattaccaa atcgctgatc aaactcggtg ggcacattat 17341 ctaattcaag ggtaggggtt agctggcgat taataccatg attttcaaaa aataagacta 17401 gtgcgtgaag ctgcctggtc agcggtggcg cttgggccat taacgcaaag cgaccatccc 17461 gttcgcactc ccataaatag gttgcgtctt cgtaatggac caagtcccac tgatgcagca 17521 agtagagttg gcggtaatgc ggtagattca ggtaaaatcg accaaaggcc cgttccttac 17581 tataccagtg attgcgaaaa tgctgccgta atcgcttttc ttcagcaggc tgattggact 17641 tggccacgca ggctaattcg gcaaagccat cctctagggg catttgttcc agccgacgat 17701 agctacgaat aaaatggaga atatggtcta cgttcaactc gtcaaaaaag gtattcatcg 17761 ataagagata aggaatggaa tagtattgtc gaagcgtcga tccggcgaaa agtaaggcat 17821 cttaattagt cataaggatc tgttttcgat atcgctttac actcgacata ctgatgccgg 17881 tcagactgac cgtttcggca accgataagc cccgatccag tgccttcttt accttggcga 17941 acttctcggc atccaggcct actggacgac caatgtgttt cccctttgcc ttggccagta 18001 gttgacctgc tcgtgtcttc tctaagatac tttcccggtc atactcggcc aaagccgcaa 18061 aaatctgtaa gactaatttc ccccctggcg tactgctatc aacgcccaga tccaatgcct 18121 tgaaatgaat gcctttccgg gcaaactcgc ccagcatact gatcaggtga tcccggctac 18181 ggcccagccg aaagaagcgg gcgaccacca ccgtatcgcc tgaacgaagt tgagacagca 18241 tggcgtctaa agccggtcgg ctagtgctga tgcctgtgat cttatcctga aatatttcat 18301 cacaatctac tttttgcagc gcatcgagtt gggtgtctaa gttttggtcc agcgtggata 18361 cgcgagcgta gccaaaaagt ttgttcatag gttcaaaaag ctggtgtcac aaagataatt 18421 aattctttat tttaggtcct actttttgaa ccctgtt //