LOCUS NC_012811:9 18203 bp DNA linear BCT 26-AUG-2011 DEFINITION Methylobacterium extorquens AM1 megaplasmid, complete sequence. ACCESSION NC_012811 SOURCE Methylobacterium extorquens AM1 megaplasmid, complete sequence. COMMENT locus start: 1138897; locus end: 1157099 FEATURES Location/Qualifiers source 1..18203 /organism="Methylobacterium extorquens AM1 megaplasmid, complete sequence." gene 0..743 /gene="" /locus_tag="" /db_xref="1138897..1139640" CDS 0..743 /gene="" /locus_tag="" /product="Short-chain dehydrogenase/reductase" /translation="MQVIVITGGSRGIGAAAARACAARGMGIILTYNSQREAAEAVVA EVEARGVRGVALPLDVSDTASFCAFRVAVADSLREVWNGIALHGLVNNAGFGLYSPLD AVTEAQFDGLFSVHLKGPFFLTQALLPLIGEGGAIVNLTSATTRVATAGVAPYASFKG GLEVLTRYMAKELGPRRVRANAVSPGAIRTDLGGGLTDEFEALLASQTALGRVGEADE VGRVIASLLADDLGWVNGQSLEVGGGYCP" gene 721..1110 /gene="" /locus_tag="" /db_xref="1139618..1140007" CDS 721..1110 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LAAAIVPEGARIMLDHVFLTVSDLGRSTAFYQAALAPLGVTDRL DYDGRDGPPGHPDLKGLGAGGRMFLWLRAGEAEGRAVHVGFVARSREEVEAAYDAALA AGAVSNCAPGPRVHYDPRYYAANVRVK" gene 1156..1269 /gene="" /locus_tag="" /db_xref="1140053..1140166" CDS 1156..1269 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LDFATEGLRCTLDIPLDQQDRFTSFRELADGRPFGTA" gene complement(1802..1939) /gene="" /locus_tag="" /db_xref="1140699..1140836" CDS complement(1802..1939) /gene="" /locus_tag="" /product="hypothetical protein" /translation="LSLESRYKRREYHPDRMHGGTLHGAAQTYNLSCFHVSFGGAVRT G" gene 2133..2942 /gene="phnC" /locus_tag="phnC" /db_xref="1141030..1141839" CDS 2133..2942 /gene="phnC" /locus_tag="phnC" /product="phosphonate transport protein (ABC superfamily, atp_bind)" /translation="MLSVEKLEVTYPGGIKALRPTTLTFRKGEFVVLLGPSGAGKSTL LRCLNGLVPATNGRVSVPELGDIAASRTVLRRHRAATGMVFQQHHLIGRLSALANVLM GRLGHQNALRSLWPPSRSDQHLGLEALERVDLLDRAVTRVDLLSGGQQQRVGIARAVA QRPRLILADEPVASLDPAAATRVLDLLRSICRADGISAVVSLHQVDLARQFADRVIGV RGGEVVFDGAPARLSDCDLERIYGARPAEALNDALEAPRARRGAIYAVQTA" gene 2955..3827 /gene="ptxB" /locus_tag="ptxB" /db_xref="1141852..1142724" CDS 2955..3827 /gene="ptxB" /locus_tag="ptxB" /product="putative phosphonate transport system substrate-binding protein" /translation="MISRRTFGAGLALSAFLRAGPSLAQGADPDTLKVALLPDESAST IIQNNQGLKTYLEQGLGKRIELVVTTDYSSMIEAMRFKRIDLAYFGPLSYVLAKSRSP GIEPFAALVSGGQPTYSSYLIANVTAGIARTEDVKGKTVGFGDTASTSSHLIPRALLK NAGLEAGKDYSFQHLGTHDAVARAVQAGHVQAGGLSKPIFTSLVATKSIDPAKVHVVA ESRPIPNYPWTVRGDLAPGLKEKIKTTFLEIKDPAILKPFKAEAFSPITDADYDVLRE TAKLLNIDLTKVKS" gene 3831..4664 /gene="ptxC" /locus_tag="ptxC" /db_xref="1142728..1143561" CDS 3831..4664 /gene="ptxC" /locus_tag="ptxC" /product="putative phosphate permease component of ATP-dependent phosphate uptake system" /translation="MAQARSLASTAGAADGYDIVLGRVRVAAVRRLLLALPAAAAVLA CLWQVGLLDPVRLAEGAPAMVQLLDEMTPPDFTRWRSWVGPILDTLAMSVAGTVLAVT LSLPLGLLAAPNTSPHPLVYRTFRLLLNALRSVPELIMGIFFVAAVGFGALPGVLALG LHSTGMVGKFFAEAIEHADHKPIEAARAAGASPLQVITHAVLPQVLPQLTDTTLYRWE YNFRASTVLGVVGAGGIGFELIASLRLLQYDQVAAIMLCILAAVTLVDALGGVLRRRL K" gene 4673..5692 /gene="ptxD" /locus_tag="ptxD" /db_xref="1143570..1144589" CDS 4673..5692 /gene="ptxD" /locus_tag="ptxD" /product="Phosphonate dehydrogenase (NAD-dependent phosphite dehydrogenase)" /translation="MRPKVVVTNPVFPETIELLRKHCDVDINPSPEPWPAVEVRRRCS DADALLAFMTDSVDAGLLEACPRLKVVACALKGWDNFDVEACTRAGVWLTAVPDLLTE PTAELAVGLAIGLCRNVLAGDRAVRAGFDGWRARMYGSGLYGSVLGVAGMGKVGQAVT RRLKGFGARELLYFDEQALPAALEVELGARRVSWETLVSRSDVLILALPLTPGTRHLL DDEALATARPGLRIVNAGRGSVVDEAAVADALAGGRIAGYAADVFEMEDWALDDRPQR IATGLLADGNRTLFTPHLGSGVVDTRRQIEAAAAHNLLAALEGRVPPDAINRPEPLRS LYAAG" gene 5720..6589 /gene="" /locus_tag="" /db_xref="1144617..1145486" CDS 5720..6589 /gene="" /locus_tag="" /product="putative transcriptional regulator" /translation="VLNLQYVETLLAVLATGSFHAAGRRLGLSQPTVSQHVRKLETAL RVTLVERDPAGCRPTPQGRALLPHAEALIRAGRRAEEAVAGNRLAIGASGNIGTFLMP EILRRYGDTGAAPADAEISTNTHLLARLEAGEIDVALLEWWEGRSGLVARVWHREPLV VIVDPSHRWARQARVTPQDLTNASLLAGEPGSGTGRVLREALGAVGASFRVDRQLGST EAVKRAVRAGLGISIVMACSVRDEVGNGVLVALPVEGAELAKSLYAAHRDPLPDTARA SGFLHVLTAAVGC" gene complement(6762..7529) /gene="" /locus_tag="" /db_xref="1145659..1146426" CDS complement(6762..7529) /gene="" /locus_tag="" /product="putative short-chain dehydrogenase-like protein" /translation="VTGGSSGIGLELAKLFAADSYDLLIAARSEHVDEVASRMREAGT SVEACRADLSTPEGVEALHAAIQAAERPLEAIAINAGVGLGGPFVENRWEDELNLMRI NVVETVHLAKLVVPGMVARGRGRVLFTSSISGTTPVPFEAVYGASKAFVLSFAEAIRN ELRDTGVTVTALLPGQTETNFFHHARMDDTSIGAGPKSEPADVAKAGYEAMMDGREKV VAGSIATHLEAAVLNRILPDSMKAERHRKMSEPGGAE" gene 7846..8340 /gene="" /locus_tag="" /db_xref="1146743..1147237" CDS 7846..8340 /gene="" /locus_tag="" /product="putative acetyltransferase" /translation="MRVAMLIRTVLSEDAPAIWSIIEPVIRAGETYTLDRDMTEEQAL AYWMGSDKETFVAEEDGVILGTYYMRPNQAGGGRHVCNCGFMVSDAATGRGVAGRMGE HALAHARSRGYRGMQFNFVVSTNERAVRLWQKLGFEIVGRLPLAFHHPAHGDVDALVM FQAL" gene 8916..9953 /gene="" /locus_tag="" /db_xref="1147813..1148850" CDS 8916..9953 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MHSLNRPAGLVAFALLGAVSMLPPGSAQAAESAQGIYVLGNRGP LAGVTPPPGFYFESETYFYQGNLSGNRTFQSGGVVAANVKLDTSATFMTPVWVTPVEI LGGNLGFSLTIPFGTPNVSAGAVFFSPRIDRIIAGRERDAVFNVGDIYLASFVGWHSG NFHWSATVLGVVPSGSYETGQLSNISLNRHALDLSGALTYLDPVLGYELSVVPGITFN WINPATQYLTGTEFHLEWSASKYLSQQLSVGVVGYFYDQLTGDGGPGNRIGPFRGQVT AIGGQIGYTFKVGEIPVSTNIRVLREFNATNRFEGTATYLTISAPLWVAPGAAVADAK PTMTNRVVRKF" gene 10007..10453 /gene="" /locus_tag="" /db_xref="1148904..1149350" CDS 10007..10453 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MGQPSRWAAAYLGLLVLQTAAASSLFWMILPILRRMISRLGEPL DLEAWRLATVTGSVIVLQSCYWIRHQRAPVYAAFRNVVIGHLLMFASRASFFFGGAFF SLIYFRHVPELSVLPPLGQGFAKALAIFVILFSLFCYSLELERLGK" gene complement(10580..11485) /gene="" /locus_tag="" /db_xref="1149477..1150382" CDS complement(10580..11485) /gene="" /locus_tag="" /product="hypothetical protein" /translation="VIGRTKTDGPADYAAVHKIQAGYKVTRLSEWGKEVKPVEIKIDP SIDMKTPPKVQVDTMPAAKYFALGAELMKLHPPHITDQPIVAQLKKIGIEVGKSFDMS KLDPEVQKALDAAPADAQRLMAWKLPTLARVVNGWSMNTDTMGVYGNYYLKRAIVTQQ GLGANVPEDAIYPLNLGDEAGKLLDGASKYTLHFDKASVPPVNAFWSITLYDPEGFQV PNALNRFAVSSWMPFKYNGDGSLDLYFQNENPGKDKEANWLPAPKGGFNLTMRLYAPK SDALTGRWNPPAVTRMQAAPALAAQ" gene complement(11433..11672) /gene="" /locus_tag="" /db_xref="1150330..1150569" CDS complement(11433..11672) /gene="" /locus_tag="" /product="hypothetical protein" /translation="LPMLDMWTDVFASPGWRTTGTKAGTFLITPPGWRPDLRDRFVEE FKLPKRDTAHRCAHALCLGDRANQDGWSGRLCRRA" ORIGIN 1 atgcaagtca ttgtgatcac aggtggtagc cgcggcatcg gcgccgccgc cgcacgagcc 61 tgtgccgccc gcggcatggg gatcatccta acctacaaca gccagcgcga ggccgccgag 121 gccgttgtcg ccgaggtcga ggcgcgaggt gtgcggggcg tcgcgctgcc gctcgacgtc 181 tctgataccg caagcttctg tgcattccgg gtggcggtcg cggactcact gcgggaggtc 241 tggaacggca tcgcgctgca cggtctcgtc aacaatgcag ggttcggcct ctacagcccg 301 ctcgacgccg ttaccgaggc gcagttcgac ggcctgttct cggttcacct gaagggaccc 361 ttctttctca cccaggcgct cctgccgctg atcggggaag gcggtgccat cgtcaacctg 421 accagcgcga cgacccgcgt ggcgacggcc ggggtcgctc cctacgccag cttcaagggc 481 gggctggagg tgttgacccg ctacatggcc aaggagctcg gcccgcgccg cgtccgcgcc 541 aacgccgtct cgccgggcgc gatccgcacc gacctgggcg gcggactgac ggatgagttc 601 gaggcgctgc tcgcctcgca aacggcgctt ggacgcgtgg gcgaagctga cgaggtcggg 661 cgcgtcatcg cgagcctgct cgcggacgac cttggctggg tgaacgggca atcgctcgaa 721 gttggcggcg gctattgtcc ctgagggagc gcggatcatg ctcgaccacg tcttcctgac 781 ggtcagcgac ctcgggcgct cgaccgcctt ctaccaggcg gccctggcgc cgctcggcgt 841 caccgaccgc ctcgactacg acggacgcga cgggccgccc ggccatccgg acctgaaggg 901 actcggcgcc ggaggacgca tgttcctctg gctgcgcgcg ggcgaggctg aggggcgggc 961 tgtgcatgtt ggtttcgtag cgcgctcacg cgaggaggtc gaagccgcct acgacgcggc 1021 actcgcggcg ggtgccgtga gcaattgcgc gccgggaccc cgtgtccact acgacccgcg 1081 ctactacgcg gcgaacgtcc gggtgaagta gcccccgaaa tgaccggaca gccgggagct 1141 cggtggcgtc gttcggttgg atttcgccac ggaagggctg cgctgcacgc tcgacattcc 1201 cctcgaccaa caggaccgtt tcacctcctt ccgggaattg gcggacggcc gaccgttcgg 1261 cacggcctga gggctgaggc ggttcctgat tgccggtcgc ttctccaacc tgagaggaca 1321 gcgcaagccc acgcgatctg tgcgtctcgg ctacgtgctt ggccgtaagt tcccgtgaca 1381 gtctgggcat ctggccgcac gcggcgtcgc tgcagtccta cggacgggca tgtgggcctg 1441 tggcctgtgg aatcaggtca cacaacgcgg cagcctgctg caaggatgcc cgatcggtga 1501 ccgtctcgcc ggtcgccgca cgcgagtgcc ctttgccttg ttcgcgcacg gcttcggccg 1561 ccggtctttc gtctgtcccc cacacccggc gcgccggcac attataaggg gccacaacat 1621 actgatgtcg tgcccacccc cggggaggtc cgcttctccg ctcggagcag acgcctcatc 1681 gagccaagcg ccaggtctgc aaagggtcag gagttcgcgc tccgattgtt ctgctgtgcg 1741 ccagcagcgg accttgagcc aaagctggaa agcggacttt cggcttcgcg catcccagtc 1801 attcacccgg ttctgacggc acctccgaag ctgacgtgga agcagctcag gttataggtc 1861 tgggccgcgc catgaagcgt tccaccgtgc atgcggtcag gatggtattc ccgcctttta 1921 tatcgggatt ccaggctcaa attccggtgc tcgggaagtt ctcgtcaccc gaacaggccg 1981 caagcatctc ctcgcgcgga gcaataggcc cgatctcacg tccccgactc agcctgagcc 2041 gagccacttc gtgtcatccg tccgtcacgt cgccccgcta ctcggatagc caatcaatcg 2101 acggcctcga ttggcttttc gaatggacac gggatgctct ccgttgagaa actggaagtc 2161 acctacccag gtggcattaa ggcgttgcga ccgacaaccc tgacatttcg caagggtgag 2221 ttcgtggtcc tgctcggtcc atcaggtgcc ggcaagtcga cccttctgcg ttgcctgaac 2281 ggcctcgtcc cggcaacgaa cggccgcgtg tcagtcccag agttgggaga catcgccgcg 2341 agccgtaccg tcttgcgccg gcaccgggca gcgacaggaa tggtcttcca gcagcaccac 2401 ctaatcggcc gcttgagcgc acttgccaac gttctcatgg gccggctcgg tcatcagaac 2461 gccctgcgct ccctctggcc cccgtcgcgg agcgatcaac acctcggatt ggaagccttg 2521 gagcgcgtag atctcctcga ccgcgccgtt acccgcgtgg atctactctc cggcgggcag 2581 cagcagcgcg tgggcatcgc acgcgcggtc gcgcaacggc cccgccttat cctcgccgac 2641 gagccggtgg ccagcctgga tccggccgcc gcgacgcgtg tgctcgatct ccttcgcagc 2701 atctgccgag cggacggcat ctcggccgtg gtgagcctgc atcaggtcga tctggcccgg 2761 cagttcgccg accgagtgat tggggttcgt ggcggcgagg tggtgttcga tggtgcgccg 2821 gcccgccttt ccgactgcga cctagagcgg atctacgggg ctcgacctgc ggaggctctt 2881 aacgatgccc ttgaggcgcc tcgcgcgcgg cggggcgcaa tctacgccgt acaaacagct 2941 tgaaggacac ccaccatgat ttcgagacgt accttcggcg ccggcctagc gctgagcgct 3001 ttcctgcgcg ccggcccatc actcgcgcag ggcgcggatc ccgacacgct caaggtcgcg 3061 ttgctgccgg acgaaagcgc atcgacaatt atccagaaca atcagggcct gaagacctac 3121 ctcgaacagg gtctcggcaa gcgcattgaa ctcgtggtca ccaccgatta ctcgtccatg 3181 atcgaggcca tgcgcttcaa acgcatcgat ctcgcctact tcgggccgct ctcctacgtg 3241 ctcgccaaga gccgttcgcc gggaatcgaa cccttcgcag cgctcgtgtc cggtggacag 3301 ccaacctact ccagttatct gattgccaac gtgaccgcag gcattgcgcg caccgaggac 3361 gtgaagggca agacagtcgg cttcggcgac acggcctcca cgtcaagcca cctcatcccg 3421 cgggccctac tcaagaacgc tggcctcgaa gccggcaagg attacagctt ccagcatctc 3481 ggcacccatg acgcggtcgc gcgggccgtg caggctggtc acgtgcaggc cggtggcctc 3541 agcaaaccca tcttcacgtc gctagtcgcg acgaagagca tcgacccggc caaggtccat 3601 gtcgtggcgg agagccgccc gatcccgaac tatccctgga cggtgcgcgg cgacctcgcg 3661 ccgggcctca aggagaagat caagaccacc ttcctggaga tcaaggatcc ggccatcctg 3721 aagccgttca aggccgaggc cttctcgccc atcacggacg cggactacga cgtgcttcgg 3781 gaaacggcaa agctcctcaa catcgacctg acgaaggtga agagctgagc gatggctcaa 3841 gcccgatcac tcgcgtcgac ggcaggcgcc gctgacggct acgacatcgt tctcggacgt 3901 gtccgcgtcg cagccgtccg gcggctcctg ctcgccctgc cggccgcagc cgccgtcctc 3961 gcctgcctct ggcaggtggg gctcctcgat ccggtgcgcc tcgccgaagg cgcacctgcg 4021 atggtgcaac tcctcgacga gatgaccccg cccgacttta cgcggtggcg ctcctgggtt 4081 ggaccgatcc tcgacacgct cgcgatgagc gtggccggca cggtgctcgc ggtgaccttg 4141 tccctgccac tagggctgct ggctgcgccg aacacgagcc cgcacccgct cgtctaccgc 4201 acgttccgcc ttctgctcaa cgcgctcagg tcggtccccg agctgatcat gggcatcttc 4261 ttcgtggcgg cggtcggctt tggcgcgctg ccgggcgttc tagcgctggg cctgcattcg 4321 accggaatgg tcggcaagtt cttcgccgag gcgattgagc acgcggacca caaaccaatc 4381 gaagcggcgc gcgcggccgg cgcctcaccc cttcaggtca tcacgcatgc cgtgctgccc 4441 caggtcctgc cgcagctcac cgacacgacg ctctaccgct gggagtacaa cttccgggcc 4501 tcaactgtgc tgggggtcgt tggcgcgggt ggcatcggct tcgagctcat cgcttctctg 4561 cgcctcctcc aatacgacca ggtcgcagcc atcatgctgt gcatcctggc tgccgtcact 4621 ctcgtcgacg ccttaggcgg tgttctgcgc cgccggctca agtgagaaac tccatgcgtc 4681 ccaaggtcgt cgtcacgaac cccgttttcc ccgagacaat cgaactccta aggaagcact 4741 gcgacgtcga catcaacccg agtcctgagc cctggccggc ggtggaagtg cgccgccgct 4801 gctcggatgc ggacgccttg ctcgccttca tgacggacag cgtggatgca ggcctcctcg 4861 aggcctgccc ccgcctgaag gtggtggcct gcgcgctcaa gggctgggac aacttcgatg 4921 tcgaagcctg cacgcgggcc ggcgtgtggc tcaccgccgt tcccgacctg ctgaccgaac 4981 cgacggcgga actggcagtt ggcttggcca tcgggctttg tcgcaacgta ctggcaggcg 5041 accgcgcggt acgtgccggc ttcgacggct ggcgagcgag aatgtacggt agcggcctgt 5101 acggcagcgt tctcggcgtc gccggaatgg ggaaggtggg gcaggctgtc acgcgcaggt 5161 tgaagggctt cggcgcacgg gagctcctct acttcgatga acaggcactt ccagccgcct 5221 tggaggtgga gctcggcgct cgccgcgtgt cctgggaaac gctggtcagc cgaagcgacg 5281 ttctgatcct ggcgcttccc ctgacaccgg gcacacgcca cctgctcgac gacgaagcac 5341 tcgccacagc gcgtcccgga ttgcggattg tcaacgccgg ccgtggctcg gtcgtggacg 5401 aagcagccgt agccgatgcc ctcgcgggtg gccggattgc gggctacgcg gccgatgtgt 5461 ttgagatgga ggattgggca ctggatgacc gcccccagcg catcgcaacc gggctgctcg 5521 cagacgggaa tcgaacgctg ttcacgcctc acctcggctc gggcgtcgtc gacacgcgcc 5581 gacagattga ggcggcagct gcacataatc ttctggccgc cctggagggc cgagtacccc 5641 cggacgcgat caaccgcccg gagcccctgc gtagcctcta tgccgcgggc tgagcccgga 5701 cagggaaaag ggggtcgcta gtgctgaacc tccaatacgt ggagacgctc ctcgcagttc 5761 tggcgacagg tagcttccac gcggcaggcc gacgcctcgg cctgtcacag cctacggtct 5821 cccagcacgt acgaaagctg gagacggcgt tgcgggtgac gcttgtcgag cgtgatccgg 5881 caggatgccg tccgacgccg caggggcgcg cgctgctgcc tcacgccgag gcgttgatcc 5941 gggccggacg gcgggcggag gaggctgttg cgggaaaccg gctcgcgatt ggcgcttcgg 6001 gcaacatcgg caccttcctg atgccggaga tcctgcgacg gtatggggac acaggcgccg 6061 ctcccgcaga cgcggagatc tcgaccaaca ctcacctcct tgcacggctc gaagccggcg 6121 agatcgacgt tgcgctactg gaatggtggg aggggcgatc cggtctggtt gcccgcgtat 6181 ggcatcgcga accgctcgtt gtcatcgtgg atcccagcca ccggtgggct cgacaggcac 6241 gtgtgacgcc acaggacttg accaacgcat cgctgctcgc aggcgaaccc ggaagcggga 6301 cgggacgagt gcttcgcgag gctctcggtg cagttggagc aagtttccgt gtcgatcggc 6361 aactcggcag cacggaggcc gtgaagcgag cagttcgagc cggactgggc atctcgatcg 6421 tcatggcgtg ttcggttcgg gatgaagtgg gaaacggcgt tctggtcgcg ctgcccgtgg 6481 aaggcgcaga actcgcaaag tctctatatg cggctcaccg cgatccgttg cccgacaccg 6541 cgcgggcaag cggctttcta cacgtcctga ccgctgccgt gggctgctga gtcactcgag 6601 aatggtttgg gcgcgggaag cagaccgccg gcctgcggcc aaaatcggcc tcttggatcc 6661 gtattttgcc tacccggaag cggacctccc aagggcctgc tttgggtcag gagttctcat 6721 gctgcttata gtcagggctc aggcagctcc caaagcccag agctactctg cgccgcccgg 6781 ctccgacatc ttcctgtgcc gctccgcctt catggagtcg ggcaggatgc ggttcagcac 6841 cgcggcctct aaatgggtcg cgatactgcc ggccacgacc ttctcccggc catccatcat 6901 cgcctcgtag ccggccttgg ccacatcggc cggttcgctc ttcggacctg ccccgatgct 6961 ggtgtcgtcc atgcgcgcgt gatggaagaa gttggtctcg gtctgacccg gcaggagagc 7021 cgttacggtg acgcccgtgt cgcgcagctc gttgcggatg gcttcggcga acgagagaac 7081 gaaggccttg gaggcgccgt agaccgcctc gaatggcacc ggtgtggtgc cggagatcga 7141 cgacgtgaac aggacccgcc cgcggccccg ggcgaccatg ccgggcacaa cgagcttggc 7201 gaggtggacg gtctcgacga cgttgatccg catgaggttc agctcgtcct cccagcggtt 7261 ctcgacgaag gggccgccga gcccgacgcc ggcgttgatg gcaatcgcct caaggggccg 7321 ctcagcggct tggatagccg catggagcgc ttcaacgccc tccggtgtcg acaggtcggc 7381 tcgacaggcc tcgaccgacg tcccggcctc gcgcatccgg ctggccacct cgtcgacgtg 7441 ctcgctgcgg gcggcgatca gaaggtcgta gctgtcggcg gcgaacagct tcgccagctc 7501 cagcccgatg ccgctggagc cgcccgtcac caccgccagc cccttgcgct ctaggcttcc 7561 catcgtcggt cccgtctccg attgccctcg cgcttgtgcg gaggcgcaac gctccggcgt 7621 tcgagatgat cccgcattag cctccatgca ctgaaggtac cggcccttag gttgcgttgc 7681 gccacgagcc gatcttcggc cgtcaggaaa tgaaccgccg cttacgaccc tttgcagaag 7741 ccgggagcgt ccgcttgcag gctgctcgat gaggcaatga cctacgtctg tcgggtggga 7801 agccgaccca cggcctcatg gctttccggt ccttgcggtt accgctatgc gcgtcgccat 7861 gctgatccgt actgtcctct ccgaagacgc ccccgctatc tggtcgatca tcgagccagt 7921 catccgtgct ggtgagacct acacgcttga ccgggacatg acggaggagc aggcgctcgc 7981 ctactggatg ggatcggaca aggagacctt cgtcgccgag gaggacgggg tcatcctcgg 8041 gacctactac atgcgtccga accaagcggg cggtggtcgc cacgtctgca actgcggctt 8101 catggtgagc gacgctgcca ccgggcgcgg cgtcgcaggg cgtatgggcg agcatgccct 8161 agctcacgcc cggtctcgcg gataccgggg catgcagttc aacttcgtgg tgagcacgaa 8221 cgagcgggcg gtgcgcctct ggcagaagct tggattcgag atcgtcgggc ggttgccact 8281 tgccttccac catcccgcac acggcgatgt cgatgcattg gtgatgttcc aggcgctctg 8341 acagcctgtc gccaaggtat gcaatgcgtc gagaacggct ggtctgctct atgaccgggt 8401 cgagtggatt tccgccggtc cgctttcggt cgacaagata gggaagagaa caacgctttt 8461 ccgcccgctc acgaccctta acgggccctg ggaaggtccg ctctcgggct gctcgatgaa 8521 gcaaagcgta cgacctggtt gggtggtttc ctgcccttcc gcttccaagc tgataatggg 8581 ctaagcggcc gttggcgttc ccagatgtcg agcccaagcg gtttcttggg ggcgggcgaa 8641 cgtctggcta cgagcgtttt ccccagaagt ttgaatagct gactggcctt ctgggcgcgt 8701 aaagcctctg gtgtggacgc ttaagttctc cgcctgccta ctcaaaaaat gtttgaggga 8761 aagcgcacat agccagacaa atcatgctga cgaacattta tgatacacag ttcttaatcc 8821 aaaatcgcgc attcgatttt tgattgatac gcccagttcg ccatgaatat atttcctctg 8881 aggatgcagc ttcggacctt gtaggtggag ggcgcaatgc acagtctcaa tcgtccagca 8941 ggactggttg catttgcctt gctcggcgca gtcagcatgt tgccccctgg tagcgcccag 9001 gcagccgaat ccgcccaagg catctacgtt ctgggcaacc gcggaccgct ggcgggcgtg 9061 acgccgccgc ccgggtttta cttcgagagc gaaacctact tctatcaggg caatctctcg 9121 ggcaaccgaa ccttccagag cggtggcgtc gtcgccgcga acgtcaagct tgataccagc 9181 gcgaccttca tgacccctgt gtgggtcacc ccggtagaga tcctgggcgg gaacctcggg 9241 ttctccttga ccatcccctt cggcacccca aacgtgagcg ccggggcggt gttcttctcg 9301 ccacggatcg accgcatcat agccgggcgc gagcgcgacg ccgtgttcaa cgtcggcgac 9361 atttatctcg cctcgttcgt tggttggcac tccggcaact tccactggag cgccacggtc 9421 ctgggcgtcg tcccgtccgg ttcctacgag accggccagc tgtccaacat ctcgctcaat 9481 cgccatgccc tcgatctcag cggggcactc acctacctcg atcccgtcct cggctacgag 9541 ctttccgtgg tgcccggcat caccttcaac tggatcaatc cggcgactca gtacctcacc 9601 ggcaccgaat ttcacctgga atggtcggcc tcgaaatacc tgagtcagca gctgtcggtc 9661 ggcgtcgtcg gctacttcta tgaccagctc acgggcgatg gaggtccagg caacaggatc 9721 ggtccgttcc gagggcaggt cacagcgatc ggcgggcaga tcggctacac cttcaaggtc 9781 ggcgagatcc cggtctcgac gaacatcagg gtcctgcgcg agttcaacgc tacgaaccgg 9841 ttcgagggga cggccaccta cctgacgatc tccgcccccc tctgggttgc gcccggagcg 9901 gctgttgcag atgccaagcc caccatgacc aatcgggttg tccgcaagtt ctgaccaggc 9961 ttaggcggaa ggtcacggtg cgtgctgccc cgagcggagg tagccgtatg ggtcaaccct 10021 cacgatgggc ggccgcttac ctggggcttc tagtcctcca gaccgcagcg gcctccagtc 10081 tcttctggat gatcctgccg attttacgtc ggatgatctc ccgcttggga gagccgctgg 10141 atttggaagc ctggcgcctt gcgaccgtaa caggaagcgt catcgttctg caatcctgct 10201 actggattcg gcatcagcgc gccccggtct acgctgcgtt ccgaaacgtc gtgatcgggc 10261 acctgctcat gtttgccagt cgcgccagtt ttttcttcgg cggcgcattc ttctcattga 10321 tctacttcag acatgtgccc gagctcagcg tccttccacc cctcggccag ggttttgcga 10381 aggcactcgc catcttcgtg atcctgttct cgctgttctg ttactcgctc gaactggagc 10441 ggctcgggaa gtaatttgag gggtcttcca aagacgtcca gggatgatgt tgatggcgcc 10501 ctatacaagg cgagcgccca tgagctgcac tgtcctttat tagctaaagc atgcttgcca 10561 gcgagcgtcc cgagccaaat tcactgagca gccaaagctg gagctgcctg catccgcgtg 10621 acagcgggtg ggttccatct gccggtcagc gcatcagatt tcggtgcgta gaggcgcatg 10681 gttaggttga agccaccctt tggagcgggc aaccagttgg cttccttgtc cttgcccggg 10741 ttctcgttct ggaaatagag gtcgagcgag ccgtcgccat tatacttgaa cggcatccag 10801 ctgctgacgg caaagcgatt aagtgcgttc gggacctgaa agccctcggg atcgtagagc 10861 gtgatcgacc agaaggcatt cacagggggg acggacgcct tatcgaagtg aagcgtgtac 10921 ttgctggcgc cgtcgagcag cttgccagcc tcatcgccga gattgagggg ataaattgca 10981 tcttcgggga cgttcgcgcc gagtccttgc tgtgtaacga ttgcccgctt gaggtagtaa 11041 ttgccgtaaa cgcccatggt gtcggtgttc atcgaccagc cgttgaccac gcgcgccagc 11101 gtcggcagct tccaggccat cagcctctga gcatccgctg gcgcggcgtc cagggccttt 11161 tggacttccg gatcgagctt gctcatatcg aagcttttgc cgacttcaat accaatcttc 11221 ttcagttggg cgactatcgg ctgatcggtg atatgcggcg gatgcagctt catgagctcg 11281 gcgccgagcg cgaaatattt cgccgccggc atggtgtcca cctggacctt cggcggcgtc 11341 ttcatgtcga tgctcgggtc gattttaatt tcgaccggct tgacctcttt gccccattcg 11401 gacagccgcg tgaccttgta gccggcctgg atcttatgca cggcggcata gtcggccgga 11461 ccatccgtct tggttcgccc gatcacccag acataaggcg tgggcgcatc gatgcgctgt 11521 gtctcttttt gggagcttga actcttcgac gaacctgtcg cgcaggtcgg gccgccagcc 11581 gggcggcgta atcaggaagg tcccggcctt ggtacccgtc gttcgccaac ccggcgacgc 11641 aaagacatcg gtccacatgt cgagcattgg caaaaggtag aagcgcccat cggtgtccgg 11701 tgccgagatt gatcggcccc cacgcggtgg tccaagttct aagttagtgc agggtcggcc 11761 tttgctccac gggtcgcttg gccggcggag ccgaccgggt gagcgcagcc ggccaagcgg 11821 tgaaggccgg cacgaacacc tctggggccg gtggccggta gccgagcgag gcgtgcgggc 11881 gcacgccgtt gtaatgtaga cgccaactct cgatcacgat ctgcgcctcc ttgagcgtgt 11941 agaagatctc accgttcaaa agctcgtccc gtagtcgtgc gttgaagctc tcgacgtaac 12001 cgttctccca tggcgagccg ggtgcgatgt aggctgttct ggcgccgaca ccggtgatcc 12061 aggcctgcac ggacttggcg atgaactccg gaccgttgtc agagcggata tggccgggca 12121 cgccgcgcag gatgaacagg tcggacagca cgtcgatcac gtccgccgcc ttcagcttgc 12181 gtgcgacgcg gatcgccagg cactcccgcg tgaactcatc gaccacgttc agcatccgga 12241 acttgcggcc ctcgtgcgtg cgggcttcga caaagtcgta ggaccagacg tgatcgcgac 12301 gctccgcccg caatcgcagg caggaaccat ccccgtccca gatgcggccg cgcttgggct 12361 gccgagacgg gaccttcagc ccctcgcgcc gccagatccg ctcgacccgc ttgtcgttga 12421 cgaaccagcc cgccgccttc agcaatgcac cgatcttccg gtagccgtag cgcccgtact 12481 ggcgagccag ttccacgagg tcggctgtca gcgcggcctc atcctctctt ccccgcggca 12541 ccttgcgctg cgtcgagcga tgctgcccga gcgcccgaca ggcgcggcgc tcggagacgt 12601 ctaggacgtt catgacatgc gcgatgcagg cgcgtcggcg cgcggggctg gtcagtttcc 12661 ccgagcggcc tcctgcagga tcagcttgtc gagggtgaga tccgcaaccg ccttgcgcag 12721 ccgctggttc tcaacctcca agtccttcat ccgtcgaacc tgatcgctct tcaggccgcc 12781 gtactccttg cgccagcggt agtaggtcac ttccgtcacg ccgatggccc ggatcgcctc 12841 cgccacgctc tggccctgcg agaccagaac atccacctgc cgcagcttgg cgaccacgtc 12901 ttccggcttg tgccgcttcg ttcccatctg tccgtcctca tctggctcaa aagccatacc 12961 tcagggcgga ccacttcaat ggctcttcgt cgggtttggt ggatcacgct gcgaggagga 13021 agcggcgacg caggaggtcg agcttggcgc ggccatacat cgaacgcttc aacagcttga 13081 ggcggttgac ctgcccctcg tcctgcccgc tgctccaggg caggcgaagg cctgcacgaa 13141 cagcggctcc atcctgagcg aggctgacgg cgaagctctc gaccacccgc acaccgcagg 13201 cacgggcgtc ggacaaccaa gcgtcgaagg cggtggtgat gccgggcttg gccggcgcgg 13261 cgccgcaacg gctgcgaacg attcgacaga accgccgacc gagcccgacg accttggcag 13321 cctcgtcatc ctgcagcacg cgcgcgacca ctgctgcggc gtcggcgtcg aggtcatccg 13381 gctcgcgcag gaggtgccac gacaactgct tcggcgaggg cagcggcggc gacgggggcg 13441 cgacctgcgc catgggcgac ggcgtcttga ggcgccagat cgtggtcctg gcggggcgcg 13501 tgcgccgctc ggacagccag cgtctgacct gcttgacggt gccgggaaag ccgcgatccc 13561 gcagctctcg ccagagctgc atggcgttct cgcaccccgc agcctggcga gcgtgcaggt 13621 gatcgagatg aggatcaagg atgctgcgcc ccggcccgcg cccgtcatgg cgtgggaagc 13681 cctcggcgaa ggcgtacttg cgcaccgtgg cgcgagccaa gccggtctcg cgattgatga 13741 gccggagcga ctgcccggcc gcacggcggc gacggacatc gtcgtagagc tcctcccacc 13801 gaccgaccgc tgcagcgcgg gcgagcgtct cggcgggtgc acgcggatag gctctggtgc 13861 gccgggtcga aggcgctggc gccgtgatcg gcggcaagag cttcaggcgc gggtggacac 13921 gggcgagcca acgctcgatc atctggcggg tgttgagcag gagatgccac cggtcagcga 13981 cctgcacggc cgccggcgcg ccaagcgtgg tgccgcgggc atactcggtc gaacgatcgc 14041 gcgccacgag ccggatctgt ggctggcggc ggagccatgc ggcccaggtc tcggccgagc 14101 ggtcagggag cagatcgaga gggcgatggc gttcgaggtc gacgacgatc gtgccgtagg 14161 tccgcccttt gcgcagcgcc cagtcatcga cgccgacgac acagggtcga ggcgccttcg 14221 gcagcggcac tccccggatc gtccgcagca gagtcgtggc gctggacggc atggccaggt 14281 gtgcgagcaa ccgggcagct ggctgtccgc cgagtgcgag accggtccgg gcctgcgccc 14341 cggccagccg gcgggtgcgt tgggcatggc gggcgagtag cttcgggaac cgttcggcga 14401 aggttcggcg ggggcaggct gggtcgcagc agtagaagcg ccgaacctcc aactgcagcc 14461 gaatggcctt gccgctggcc ggcaaatcgg caggccgtcg tcgataccgg ctatggaccg 14521 acgtgctgat ggctcggcac gtcgggcagc gggcgtggtc gggcttcgct tcggcgacga 14581 gggtgagggc ggtggggccg tcccgcgcga cgcggacgag gcggcagcca ggcaaaggga 14641 tgagctgggt catgccccga tctgcgaggc tgaaccgacc acgccaagac cccaaccgtc 14701 acgcacctcg atccaccaaa ctcggcgatg aaccacttca gtgggggcgg atcacgcgtg 14761 caacccgcaa tccggcgcga tcccgtatgc cgacggccgg catcttctca acaaccattc 14821 ccgcgagtcg gcggacttcc gtttccggcc gacgggatgg ttttaccgag ccgccctgcc 14881 tgatggacat ccagaccgac ccgatgccta tgggcaatcg cctaacttgg agggaaatga 14941 tgttctgaac gacaaatggg tgccaagtcg ccatcgcgcc cggttaacta ggggcaaccg 15001 ccttacggac tggaaacctc tgtagctcca ccacccaaat cctttcggat ctggtggata 15061 cgacatccta gcccgtctta ttcacgaggg cagtggatct gtggtggcga gcgtagcgta 15121 aagcattgat gtggcttagg gattgggtgc tgacgccaag tcctcagacc agatcgagcc 15181 cgccacgccc gccatgtccg atcctacgtg tctgccgttc gcgtttccat cggttcgagg 15241 caagaagctc acagctgctt tcgacggcgg acgcctgacc tcggacgggg gcgtcctgtt 15301 gctcgctcag gctgcccggc ggatgcagat cggtgagaag ctcgccgcgg tgatccccga 15361 ccggcgtgac ccgagccgga tcgtgcatcc tctgcccgag atcctgctgg cgcgcatcct 15421 ggccatcgcc tgcgggtacg aggatgccga cgacctcgat cacctgcgcg tcgatcccgc 15481 cttcaagctc gcctgtggtc gcctacccga cagcggacgc gacttgatga gccagcccac 15541 cgtctcgcgg ctggagaaca cgccgggcct gcgtgacctg atccggctcg gacgggtgct 15601 ggtcgacctc tactgcgcca gctacgccgc gccaccggcg gctgtcacgc tggatatcga 15661 cgacacctgc gacgtggtcc atggccagca gcaactgtcg ctgttcaacg cccaccacga 15721 cgaacgctgc tttctcccca tccacgtcta cgacaccgcc acctcgcgcc cggtggcgat 15781 gatcctgcgg ccgggcaaga cgccttcggg tcgcgaagtc cggggccatc tgcgtcgtct 15841 ggtccgggcg atccgccgac actggccgac gaccgcgatc acgatccgtg gcgacggcca 15901 ttacgggcgg cccgaagcga tggactggtg cgaggacaac gacgtcgctt acgtcttcgg 15961 cctgaccggc accaagtcgc tcaccgccaa ggtcgagccg accgccgatc acatccgggt 16021 cgagcgggcc ctcagcaaca cagatgccgt gcgcggcttt gctgagacca cgcacgcagc 16081 caaatcctgg cggcagcacc gccgcgtcgc cgcccgcatc gaggcgaccc gccttggcct 16141 cgacatccgc tacgtggtca cgaacatcgc caccggtacg cccgaatggc tctacgccga 16201 gctgtactgc gcccgcggac aggccgagaa cctgatcaag ctccataagg gccagctcgc 16261 ttccgaccgc acctcctgcc ggcatccggc cgccaaccag atgcggctcg tgctgcacac 16321 cgccgcctat tggctgatgc tgaccgtgcg cgacgccatc ccggctcccc atcgcctggc 16381 caaggccgag ttcgcgacga tccgcctgcg cctgctcaag cttggggctc gcatccacga 16441 gaccactgcc cgtgttcgtc tcgccttcgc cgccgcctgt cccgaggccg acttgctgcg 16501 ccatatcgcg ggcgcactcg ccccagcgcc agcctgaacc acggggcgtg atgccccatc 16561 gacaccgctc ccgtccctcc agcgccgaca gcacaaccag atccatacgc gtcaggacag 16621 acgcacgatc ccgctcgcct tcagctcaaa acacgtcgcc agccaaaccc tggtgaataa 16681 agcgggctag tcccacgcgg gatgaggaag gcggagtcgt gccgtaaaac acgttcgttg 16741 agcggtatcg ttcgagaggg gggctgcaag aactgccctg gctccatgcg ccgctatcca 16801 ccccgtcgcc caacaggagg ctaaccacga cagcaagcaa cgccaagctc agacgcgacg 16861 aagacgctta agctttcgcc taaacgcctt cgaagctgag aaatcatccc ccgatccttg 16921 caagaaaacg ggatgatcag tctaaaatcc tgtgacacgg cgcaagcgcc ggcgcgcgaa 16981 gatttcacgc gtggagggtg ccataggcgg agtccgcctg caagtctcca cccggtctca 17041 gcttactcag cctatggctg ccggagaaac gacgccccca ctagggcgaa cgcccccggc 17101 tgcctccgtc cattccggcg caccacaagc gccaaaagac gcacgaggat gcgatgcccc 17161 atatgatcga acgatccccc gacgactggg agtcgccggc cgaaagcctg gccgaccggt 17221 tccccaccaa gttccgctcg aaggcgtcca cgcagggcgt gctcgtcacc acggattcgc 17281 ggccgcgcca gatcttctgg gacagtctcg gtgaattcgg cacgctcacc agtgtgctcg 17341 cccggcgcga catcgtcgag gtgcgcgagc agcaggaggc gctctatcgc gacgcggagg 17401 gtgtcgtccg ccgacacttc ttcgacttcg ttgtcacctt cgacgacggc acccgccggg 17461 cgctcgccta taagccgcgc gaccgagccg agaaggtcgg attcatcaac ttcctgaccg 17521 acctggccga acggatctcc ccggagatcg ccgacgagat cgtccccctg accgagttcg 17581 atctcccccg cgcgaccgtt cagaacgcga tcctcattca cgactgccag cgcgatccgc 17641 cggatgacaa ctgtccgtcg tcagatgatt tgggacattc agcggtgttc aggagcggag 17701 gctctggtcc atctggggtg agaggttagg cagcctgcgc gtgatggcgc aagcggcgat 17761 ccatcagggt ctggcgtttg atgcgttccc gctcggccag gatcccttcg ccgcgtccga 17821 agtagacgtc agcgggcgtc aggttgctca ggctctcatg ggctcgggca tgattgtagt 17881 gttcgacgaa gtcggcaacc tgcgtctcca gctcgccggg caagtaggcg tgttcgagca 17941 ggatgcggtt tttgagtgtc tgatgccaac gctcgatctt gccctgcgtt tgaggatggc 18001 atggcgcacc gcggatgtgg gtcatgcccc gaatgccgag ccagtcagcc aggtcgctgg 18061 cgacgtagct cggcccgttg tcggagagca ggcgtggccg ctgcatcacc cgcgcctgat 18121 cgagcccagc cgcacccagc gccaggtcga gcgtggcggt gacgtcgctg gcctgcatcg 18181 tggcgcacag cttccaggcg acg //