LOCUS NC_012623:1 17897 bp DNA linear BCT 06-SEP-2013 DEFINITION Sulfolobus islandicus Y.N.15.51 chromosome, complete genome. ACCESSION NC_012623 SOURCE Sulfolobus islandicus Y.N.15.51 chromosome, complete genome. COMMENT locus start: 160224; locus end: 178120 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.634971; n0_4mer:D = 17.071984; n0_4mer:PS = 25.922768 FEATURES Location/Qualifiers source 1..17897 /organism="Sulfolobus islandicus Y.N.15.51 chromosome, complete genome." gene complement(-265..4) /gene="" /locus_tag="" /db_xref="159958..160227" CDS complement(-265..4) /gene="" /product="4Fe-4S ferredoxin" /translation="MMDILKRLSLNKYNVDRTTHIEVNTDICLTCKDKPCTKVCPAGT YEPSPDGRIIVHYERCLECGAALVACPYGAIKFRFPEGGISYKYG" gene complement(1..1224) /gene="" /locus_tag="" /db_xref="160224..161447" CDS complement(1..1224) /gene="" /product="FAD dependent oxidoreductase" /translation="VSFDADIVIVGGGLAGLSAAITANREGLSTIVLERGEYSGSKNV SGGRMYVHALSQLFPDALERAPLERPVTKETYEIYCEEGKKITFSFQHKTKNSYTILR AKFDQWLAKEAENEGVLISYTTLIINARREKDYVVIETNRGELKAPLVIDAGGITAPV SRFLGVKKLEPKTLMLGVKEVLDIKPEIPENEGEARTIMGLIGNLKGGGFVYTNKDTL SIGVTIKVESLYNSSIPSHEIVERFRESLGLSGNILEYSAHLIPYYGYDKIGKIHDKN LILVGDAAGFLINDGFNIRGMDLAIGSGIIAGKAAKKIKELNDYSRTDIYYEMLKESF VLKDMKTALRSFSVLSEEEVFTKYPKVICNVLGKLFTVTGDGKERPINVLLQESKSEN VNTTKMLSDLMRLFI" gene complement(1244..1600) /gene="" /locus_tag="" /db_xref="161467..161823" CDS complement(1244..1600) /gene="" /product="hypothetical protein" /translation="MFGKLVAVIDKLNEGNVIEAGNELLSVAKDYENQDKIIDLLAEI EKEIKEFRSSNDFLHRDDSPFMEVVKKSIEDMRVCRENKLKALILHTLYIISNGNEIL LNMIKKANIGKPNTYI" gene complement(1629..2048) /gene="" /locus_tag="" /db_xref="161852..162271" CDS complement(1629..2048) /gene="" /product="UspA domain-containing protein" /translation="MKRILVGYDGSENAERALDFAIELASKFSARLFVVEVIDLTLFY NSGVLPPLEATKSLEEKAKKDVKKAIEKAKSKGVDTEGITLEGDPAHSILEFAKDNQV DVIVIGSRGLSKVQRIFLGSVSNKIVQESRIPVIVVK" gene complement(2083..2961) /gene="" /locus_tag="" /db_xref="162306..163184" CDS complement(2083..2961) /gene="" /product="aldo/keto reductase" /translation="MEDVKKFKYFTVSSLAFGTWRIGGGYWYASHDRDNEWVSAIRKA IELGIRLIDTAEMYGNGHAEELVGEAIKRFNRDELFIVSKVWPSHAEYDNVIKSAKNS SKRLGTYIDLYLLHSPSRVPICKTISAFEKLVDDGVIRYFGLSNFDVDQIERARECVS KYEIVAIQNHYSLLNRDDERKALAYAEKNGLMYMAYTPLENGILARNEFLASIGKRYN KTATQVALNWYITGRNSLIPIVKASKIPHVEENAGAMGWRLSEEDWREIDEHFREKSY FLDKFVSSLKSIRPWS" gene 3063..4100 /gene="" /locus_tag="" /db_xref="163286..164323" CDS 3063..4100 /gene="" /product="pyruvate dehydrogenase" /translation="MIIKPEPSLKDLSYLIESSGLKPSDLLNMYRRMLTIRYFEETIR KIYHEGKNPFNMASGIIRGEMHLSIGQEAVAVGTLYKVRDEDVVVSTHRPHHHAIAKG VDANKLVAEILGKVTGLCRGKGGHMHLFDKTKNFACSGIVGASFPQAAGAAFAFKYSG KDNVAIAFAGEGAANHGTFAETLNIASAWELPLILVIEDNKYADSTPKSFVMSTTFHY QRGLTYNVPSYLVDGMDVIDVYSTARKAIERARKGFGPTLIEALTYRYVGHFEGDSEE YRTKEEVEMWSSLDPIRRLENRILRLNYADNEILAKLREEARKQVQDAIDFALRSPYP DPNEALTGVFA" gene 4327..4482 /gene="" /locus_tag="" /db_xref="164550..164705" CDS 4327..4482 /gene="" /product="" /translation="MVTPGLPHQNNLQQIGYKLLSMLNFKGKKGEEVARTLISACLWN DSVESKS" gene 4641..4790 /gene="" /locus_tag="" /db_xref="164864..165013" CDS 4641..4790 /gene="" /product="hypothetical protein" /translation="MKPWIEYYNGPVPYEHLSARHKTGATGYSCVRKYVSRRLKVFIK THLEP" gene complement(4755..5993) /gene="" /locus_tag="" /db_xref="164978..166216" CDS complement(4755..5993) /gene="" /product="transposase mutator type" /translation="MTKSKNNPGRGNTIRESNTMKVMEEIREKIRKAIKEGVSLREIE EIILQEAMMEEREAYLEVEDDHKNGTYFRYLGTGDGVLRLRVPRTRKGGFRPKILPEK YERTSPDYEDFLQQLVLSGMTPSQVKAVLAAKGIPYSEIVMNRVAERISNKLKEYKSR ELPHDLLALYIDVKIVKVRISESIMERAIYIAIGVDLEGNKFVLDYEVRDREDLDGWK SFLSGLVSRGVSRVDVIVSDDFSGLDRVVSTLFPSSQHQLCITHMVRNLMRVLPDKEE LMIRVRDLKSSRKVEEGRKAILSLSQLVQPFSPARAKRLLDAADKYCSFLNFPREIRH YLYTNNTSESFNSILARFEEELGGYFPSLRSLEVYLYVSIHESNSRWKFRPMSVIRHY SYHLKQLHASRFQVSLDEDF" gene 6066..6536 /gene="" /locus_tag="" /db_xref="166289..166759" CDS 6066..6536 /gene="" /product="" /translation="VPVGDVKVFEEFDGDYTTNSKRHRRDEQVKFRLLVYSKEEVRRK SLVYFARATNLDLSKREVLDLYNKVRGPIETSYRNIKAFLPFTGSTKFVFRTLIFVLA VAFYSLYTVFKGEVGREEFRLLLILLFPDLFNPENFTFNVIETLIYTIDLFLRR" gene 6765..7739 /gene="" /locus_tag="" /db_xref="166988..167962" CDS 6765..7739 /gene="" /product="transposase IS4 family protein" /translation="MLNFQGEKVEKVAKTLIPACLWNDSVENKSRAYDVSPQTVRNYV VKQGMEVIEKLLERARKISLEILKGVKEIDLSIDWTTKTWYGKPVKGSSEKGNSWNYA TTKYKGKVLLLAFIPQVNGMTKDEIVKVLVEQVMAMGFKIRLMTLDAGFYTVDVLNFI SQFKYIVAVPVGDVKVYEEFDGEYMTNSKRHRRDGQVKFRLLVYSKEKVRRKSLVYFA RATNLDLSKREVLDLYNKVRGPIETSYRNIKAFLPFTGSTKFVFRTLIFVLALVLYSL YTIFKGEVGREEFRLLLILLFPDLFNPENFTFNIIETLIYTIDLFLRR" gene 8755..9030 /gene="" /locus_tag="" /db_xref="168978..169253" CDS 8755..9030 /gene="" /product="AbrB family transcriptional regulator" /translation="VLSYEYILRVDEKGRIMIPKEVRDKLKIFNSVRLIVNESGEIII KKMERNIEKYAGYFRVDWSKLAGMDIDKILDEALRERSEKWLRDILT" gene 9006..9140 /gene="" /locus_tag="" /db_xref="169229..169363" CDS 9006..9140 /gene="" /product="hypothetical protein" /translation="VVKRYFDVNVFLYFLTNHPNYFQRAKEWFQNTNEIYTGEITIIN" gene 9149..9340 /gene="" /locus_tag="" /db_xref="169372..169563" CDS 9149..9340 /gene="" /product="hypothetical protein" /translation="LKKLTGKSDEEILNVLSSFFRDAEINLDHLETSDLEKVREIVEK FKLDFEDAIHFFYRKRLVS" gene 9429..10013 /gene="" /locus_tag="" /db_xref="169652..170236" CDS 9429..10013 /gene="" /product="hypothetical protein" /translation="MIYVFKGLSGYIILFLLMIGEGLGLPLPSEVIMPLVGYYSYLGS ISLYIAIIVGTLGSLVGSIIAYVIGYNLGLPFLKRYGKYILIDEGKIEALHNWFLRYG DIAVFGFRFVPGLRALISYPAGIGQMKIPKFLGFTFLGHTIWDIVLSLVGYELANQIN FVVTLAEKFGNYILIVVVIIIVIYILVRVLRNRQ" gene 10108..10725 /gene="" /locus_tag="" /db_xref="170331..170948" CDS 10108..10725 /gene="" /product="hypothetical protein" /translation="MAKSTTTKVGSAIGRTIVYIILYVTVSAIVKFLIEVLLPSVHLN AVSYESYIQILLALAFGYLIVSGISLIFYYSLLPKYGHPTATAVRNVMRIIGIGALVA AIAGAVAGGAAGVALGGFIGIVIGFASQQVLGQAVAGMFLLIARPFKINDNVNLVGED GIVEDVSTLFTTVIKSDGTKVLIPNNAIIGNKIYLKPVQQQQKSS" gene 11139..12455 /gene="" /locus_tag="" /db_xref="171362..172678" CDS 11139..12455 /gene="" /product="hypothetical protein" /translation="MNDEELLKIMSEWNFWGKEKPKVGIERECYVERIIKLLNSVKVI AISGVRRAGKSFIVREVLNRLINNGVNPEDTLIIRLDDERLLNLNYELLLKIYNLYLT YVKKDKSKPTYLVLDEAQEVEGWERFVRGLEERCEAKIVVTGSSAKLLSSEFTTLLSG RHVEVRVTPLSFLEVLEFKGIKIKGVLELAENIDRIGKELVEVMNYGGFPDVVLNPEV RAELVHSYFDTIIVKDVVNRYKLRREDKIRTLAKFYVSSSASKITYNSVSKFLKIPVK TVERYSEYLEKSFLVFFLKNYSISPKAVENSPRKVYVIDNGFLKYFSTASLGRIFETL IVQHLYRYAVRRFYELYYWSSEDSEIDVILKSGKKILPIQITYELNDENEERELKSLK KFKKYANYDNSLVITFEQEIEIEGIKVLPAYKFLLNLEDLLDSLIS" gene complement(12763..13830) /gene="" /locus_tag="" /db_xref="172986..174053" CDS complement(12763..13830) /gene="" /product="transposase IS116/IS110/IS902 family protein" /translation="MVGSISEAKSSVSGVTDPYCRTEHCGKIHPYRCDKEVGVLGIDV SKDNLITSRGGKYENNLKGYEKILDMKPCTIVLEPTGVYSIKPSQYFKEKGIRVLQVS PNVLSREKDFREKKTDFYDAEKLENMVDKAKEYEYNVLRELVTLYLFLKDMEVKQKNR LKRALFLVSDNDKINKERLERLASGDFAQEVLYQLEYTPIVLEEVKILAKALFETQEK LKEVKEMIESQVPEDHVLLTIPGVGKLAAGIIIGVVGDIRRFPKPESFVAYCGLDPVV ERSGKAVVSKGISRRGNKYLRSLFYFLAQMNCSKNPTLLRFYESHKDKLHGRKLYTAL ARKLAKVVWSVWYNNKPYEPK" gene complement(13857..14582) /gene="" /locus_tag="" /db_xref="174080..174805" CDS complement(13857..14582) /gene="" /product="hypothetical protein" /translation="MKWGPSLLLLTLLLLPIFFLPTNGLIARFGWGGGASYSTYSENI VVQPSSTQLVTVSQTGSSLLNLPWLNPTYVSIYNTYYLQVLPNQEYISNNVSLSLSSS QIALNVTWLLASSSNTGSYGSIAIGYGVNFPSGFTGSYASALPYASDGIVVYLEKGSF PTYRIFVYFDGVKQLNVSVGSISVGQQIGLGFWYLPASNQLYVYYYNGTLKTFSIIPD QVINNQFSSLSLNTYIGFISSRE" gene complement(14622..14852) /gene="" /locus_tag="" /db_xref="174845..175075" CDS complement(14622..14852) /gene="" /product="hypothetical protein" /translation="MKIYFPSLCISPPPSPSVQISQQPAIVVNQPPPPWYVQYIPEFI IVAGIVATVLTFYFSPELRNGLISKIRRYTRK" gene complement(14899..15810) /gene="" /locus_tag="" /db_xref="175122..176033" CDS complement(14899..15810) /gene="" /product="hypothetical protein" /translation="MRKALLALLTLSIELLILATPTGAITASQIGASQIVNTYNSDNW AGVAYSVEWKSWFTNYWGPILWASESIYVGNLTLGYISYPNYIYTEDISIWIGLSPAQ IGYGTDSSSGSEQTNFIQAGFDIDVGSYVSVNYFVTTIVNGQLVYNNENYVPAGKATY LDVFLENLGNGTALAQLYVYYANGTYWTTTIYTSIPWTNTGSAMSIVEAPSFSTSGPY AELPYVSGGMIHFTFSYVGSDGNEHIGPSNNPVGNMYADVYTLNEPSTYNVAQAQIYN GWANNNGGWDYLYQFYYPGAGQTTYGL" gene complement(15847..16194) /gene="" /locus_tag="" /db_xref="176070..176417" CDS complement(15847..16194) /gene="" /product="hypothetical protein" /translation="MRILKIVWILFILLNVYDVIISAIYWLKENAIFEENYFIWFYYY YEGHISFILALLMLISVKLLFFTGVYWYTGLFDLLKVSKYKWLSLLPFVVLSILIDTQ NTFILLFNYAPPF" gene complement(16204..16410) /gene="" /locus_tag="" /db_xref="176427..176633" CDS complement(16204..16410) /gene="" /product="" /translation="YLYKLLTSKAVSPYVYPLCLMPLSSSVSLKQHIRYTEHAKTCPV CGKEFAKTDALLDHVCKKHNICVS" gene 16614..17637 /gene="" /locus_tag="" /db_xref="176837..177860" gene complement(16806..16873) /gene="" /locus_tag="" /db_xref="177029..177096" CDS complement(16806..16873) /gene="" /product="tRNA-OTHER" /translation="YDVRPPYLALVRQRSRVQIPAA" gene complement(17589..17897) /gene="" /locus_tag="" /db_xref="177812..178120" CDS complement(17589..17897) /gene="" /product="zinc finger C2H2-type domain-containing protein" /translation="MLYVSLRAVYKWVCPICLTPFETYQAFIMHLRYEEKEKTCRYCG KTFANTDGLLDHIGKKHVWLPWGRHKERGGDGDPTTTLNPSKSYAICSILDNHSAYLR" ORIGIN 1 tcatataaat aacctcataa gatcagataa catcttcgta gtatttacgt tttcgctttt 61 actttcttga agcaaaacgt ttattggcct ctcctttcca tcgccagtca ctgtaaataa 121 cttgcctaga acattacaaa taaccttagg gtacttagtg aaaacttcct cctcacttaa 181 tacactaaaa gaccttaaag ctgttttcat atcctttagc acaaacgatt ctttgagcat 241 ctcgtaatag atatcagttc tactataatc gttaagctcc ttgatcttct tggcagcctt 301 tccagcaata attccagaac ctattgccaa atccattcct ctaatattaa atccgtcatt 361 tattagaaat ccagctgcat cgcctactaa gattaaattc ttgtcatgaa tcttacctat 421 cttatcataa ccgtaatatg gaattaagtg tgcggagtat tcgagtatat tcccgcttaa 481 gcctaacgat tccctaaatc tttccacaat ttcatgtgat ggtatactag aattatataa 541 cgattcaact tttatcgtaa cacctatgga taatgtatcc ttatttgtgt agacgaaacc 601 tcctcctttc aaatttccta ttaaccccat tatagttcta gcctcaccct cattttctgg 661 tatctctggt ttaatatcca acacctcttt aactcctaac attaaagttt taggttctag 721 ttttttaact cctaagaatc tagacactgg agcagtaatt ccacctgcat ctataaccaa 781 aggtgcctta agttcacctc tgtttgtttc tattaccacg tagtcttttt cccgtctagc 841 gttgattatg agcgtagtat aagaaatcaa tactccctca ttttcagcct ctttagctag 901 ccattgatcg aatttagccc ttaatatagt ataactattt ttagttttat gttggaatga 961 aaaagtgatt ttctttcctt cctcacaata aatctcatat gtttctttag ttactggtct 1021 ttctaagggt gctctctcta atgcatctgg aaatagttgt gataatgcgt ggacatacat 1081 tcttcctcca gaaacgtttt tacttccaga atattctccc ctttctaata caattgtaga 1141 caatccttct ctgttcgcag taattgcagc agaaagtcca gctaatcctc ccccaacaat 1201 tacaatatcg gcgtcgaagc tcacactatt atattttgaa aggtcatata tatgtgtttg 1261 gctttcctat atttgctttt tttatcatgt tcaataatat ctcatttcca ttactaatta 1321 tgtaaagtgt atgaagtatt aatgctttta atttgttctc cctacatact ctcatatctt 1381 caatactttt cttaaccact tccataaaag gggaatcatc tctatgtaaa aagtcattac 1441 tacttctgaa ttcctttatc tctttctcta tttcagctag caaatctatt atcttatctt 1501 gattctcata atcctttgct actgatagca actcattacc agcttcaatc acgttacctt 1561 cattaagctt atcaataacc gctactagct ttccaaacat aaaaaataat ttgaattcgc 1621 tcccttattt acttaactac aattacggga atcctggatt cttggacaat tttattcgat 1681 acactcccta ggaatatgcg ttgaaccttt gataaacctc tactcccaat tactattaca 1741 tcgacttggt tatctttagc aaactctaga atagaatgag ctggatctcc ctctaaagta 1801 ataccctctg tatctacacc tttgctttta gccttttcta ttgctttttt aacatctttc 1861 ttagctttct cttctaagct cttagtagct tctaatggag gtaatacccc tgaattataa 1921 aacaatgtaa ggtctataac ttctactaca aatagtctag cggaaaattt actagccaat 1981 tctattgcga aatctaatgc tctttcagcg ttctccgaac catcatagcc aactaggatt 2041 ctcttcatag atattaacca gattacatgg atttaaaatt aactaggacc aaggtcttat 2101 cgatttcaga gacgagacga atttatctaa aaagtaactc ttctctctaa aatgctcatc 2161 tatttccctc caatcttctt ccgacaatct ccagcccatt gcaccagcat tctcctcaac 2221 gtggggtatt ttggaagcct taactattgg tattaaacta tttctaccag tgatatacca 2281 gtttaaggct acttgggtag cagtcttatt gtacctctta cctatgcttg ctaagaattc 2341 gtttctcgcc aatattccat tttccaatgg agtataagcc atgtacatca atccattttt 2401 ctctgcataa gctaaagctt tcctctcatc atccctattt agcaggctat aatgattctg 2461 aattgccaca atctcgtatt tactaacaca ctctctagct ctctcaattt gatctacatc 2521 gaaattgctt aggccaaaat accttattac accatcatca actaacttct caaatgcact 2581 tattgtctta caaatgggta ctcttgaagg ggagtgaagt aaataaaggt cgatgtatgt 2641 gcctagcctt ttagaactat ttttagctga ctttatcaca ttatcatatt cagcatggct 2701 aggccaaacc ttggagacta taaacagctc atctctatta aatctcttaa ttgcctcacc 2761 tactaattcc tcagcgtgac catttccata catttcggca gtatcaatga gccttattcc 2821 tagctcaatt gccttacgaa tcgcactcac ccactcgtta tctctatcat gagaagcgta 2881 ccaataacct cctccaattc tccaagttcc aaaagccagt gacgatacgg taaagtattt 2941 aaatttctta acgtcctcca taaatatatc ttaaatttgt accttttaaa aattgcttct 3001 taatgtacat catatctaat ataggaagaa aaggatataa gtacataatt taatttatta 3061 atatgataat aaaaccagaa ccctcattaa aggacttatc atatctaata gaaagttctg 3121 gactgaaacc gagtgatcta ctcaatatgt ataggagaat gttaacgata aggtattttg 3181 aggaaacgat aagaaaaata tatcatgagg ggaagaatcc cttcaatatg gcttctggta 3241 taattagagg ggaaatgcac ttatccatag gtcaagaggc agtagctgta ggtacattat 3301 ataaagttag ggatgaagac gtcgtagtga gtactcatag acctcatcat catgcgattg 3361 cgaagggcgt agacgcaaac aagctagtag ctgaaatttt aggtaaggta actggacttt 3421 gtagaggaaa aggaggacac atgcacttgt tcgataaaac taaaaacttt gcttgtagcg 3481 gtattgtagg ggcatctttt ccccaagctg ctggtgctgc tttcgcattt aaatattctg 3541 gtaaggataa cgtagctata gcatttgcag gtgaaggagc agcaaatcac ggcactttcg 3601 ctgaaacgtt aaatatagca agtgcatggg aactaccatt aatattagtt atagaggaca 3661 ataagtacgc tgattccaca cctaaatcct ttgtaatgtc aactaccttt cactatcaaa 3721 ggggattgac atataacgtt ccgtcatatc tagttgatgg aatggacgta atagatgtct 3781 attcaactgc aaggaaggcg attgagaggg ctagaaaggg ttttgggcct acattaatag 3841 aagctctaac gtatagatat gtgggacatt ttgagggaga tagcgaggaa tatagaacta 3901 aagaggaagt cgagatgtgg agttcactag atcccataag gagattggag aaccgaatat 3961 tacgtttaaa ctatgcagat aacgaaatcc tagctaaatt aagagaagag gctagaaagc 4021 aagttcaaga tgcaatagat ttcgccctta gaagtcccta tccagaccct aatgaggcat 4081 taacgggtgt cttcgcatga aaataagggg aattgcacaa gcgatttcag aagcgataaa 4141 gcaggaaatg gaaagaaatg acagaattgt ggtgttcggt agacccaaaa tcgtattatg 4201 aaaaataatt ctaacagaat aatatcgatt catgatagat aacaggattt atatgagtat 4261 taagaattca attgaagaaa gggtttaaga tgagggagat gtggtattac cacgtgacat 4321 aggaagatgg taacacccgg tctccctcac caaaacaact tacaacaaat aggatataaa 4381 ttactttcca tgctgaactt caagggaaag aaaggggaag aggtggcgag aaccctcatc 4441 tcagcgtgtt tatggaacga ttcggtggaa agcaagtcga gagagtgtcc caagtgcaaa 4501 taattgaata aatctatgta aaggtttata gctaataatt caaaagatat cgtgaattac 4561 tgagaaattt tgaattttcg cttgaagcaa aaagtcgcgt aatatttaaa gggaaccggg 4621 acgatgtagt accgattcac atgaagcctt ggatagaata ctacaacggc ccggtcccct 4681 atgaacattt atcagcaagg cataaaacag gggctactgg gtatagttgt gtaagaaaat 4741 atgtaagcag aaggttaaaa gtcttcatca agactcacct ggaaccttga agcgtggagt 4801 tgtttgagat gatatgagta atgccttatc accgacatgg gcctgaactt ccaacgcgaa 4861 ttactttcat ggatcgaaac gtagagatag acctccaagg agcgaagaga gggaaagtaa 4921 cctccgagct cctcctcgaa cctagccagg atcgagttga aactctccga cgtgttatta 4981 gtgtagaggt agtgtctaat ctccctgggg aagttgagaa aggaacaata cttgtcagca 5041 gcgtcaagaa gcctcttggc tcgggctgga gaaaagggtt ggacaagttg gctgagggac 5101 aatatagcct tccttccctc ctccaccttc ctggaggact ttagatccct aactctaatc 5161 attagttcct ccttgtctgg gaggaccctc atgaggttcc taaccatgtg tgttatacag 5221 agctggtgtt gagaggaggg aaagagcgtg gacacgacgc gatcgagtcc agagaagtca 5281 tcgctcacga ttacgtcaac cctgctgact cccctgctta cgagtccgct caagaaggac 5341 ttccaaccgt ccaagtcctc cctatcccta acttcgtagt ccaagacgaa cttattccct 5401 tctaagtcaa ctcctatggc aatgtaaatg gctctctcca tgatcgactc gctgattctg 5461 acctttacga tcttcacatc gatgtaaagg gctaggagat cgtgaggtag ttcgcggctc 5521 ttgtattcct tgagtttgtt ggatattctc tcggcaaccc gattcattac gatctcacta 5581 tacggtattc ccttggctgc taacacggcc ttgacttgac ttggagtcat gcctgataga 5641 acgagctgct ggaggaagtc ctcgtaatct gggctggtcc tctcgtactt ctccggaagg 5701 atcttgggtc tgaagccacc ctttctggtt ctcggtactc tgagtcttaa tactccgtct 5761 ccggttccca gatatctgaa gtaggtcccg ttcttgtggt cgtcctcaac ttctaggtag 5821 gcttccctct cttccatcat ggcctcttgc aagattatct cctctatttc ccttaggcta 5881 actccttctt tgattgcctt tcttatcttt tctcttattt cttccattac cttcatggta 5941 ttactctccc ttatggtatt accccttccg gggttatttt tactttttgt cattattttt 6001 caccttttgc taccacaact ataactggta gccccttcat ttcacagttt aagtatatag 6061 ttgctgtgcc tgttggggat gttaaggtgt ttgaggagtt tgacggggat tacacaacta 6121 atagtaagag gcataggagg gatgagcagg tcaagttcag gcttctcgtg tacagcaagg 6181 aagaagtgag gagaaagagt cttgtttatt ttgctagggc tactaatcta gacctatcca 6241 agagggaagt gttggatttg tataataagg taaggggtcc catagagacc tcttatagga 6301 acattaaggc ttttcttcca tttactggtt ctactaagtt tgtttttcgc acgttgatct 6361 tcgtgctggc cgtggccttc tactccctgt acaccgtgtt caagggggag gtggggagag 6421 aggagtttag attattatta attcttttat ttcctgattt attcaatcca gagaatttta 6481 catttaatgt aattgaaaca cttatttaca ctatagattt atttttaagg aggtgatttt 6541 gggtctaccg tgttcggtag acccaaaatc atattagaaa aaatatttct agtaggataa 6601 tatcgaattt ataaaagata aagaaattta taagagtata aagaattcaa ttgaagaaag 6661 ggtttaaggt gagggagatg tggtattacc acgtgagtaa gtgagatggt aacacccggt 6721 ctccctcacc aaacattcaa caaataggat ataaattact ttccatgttg aacttccaag 6781 gggaaaaggt agagaaggta gcgaaaactc tcatccccgc gtgtttgtgg aacgactctg 6841 tagagaacaa gtccagagcg tatgacgtat ccccacagac cgtgaggaat tacgtagtga 6901 aacaagggat ggaagtgatt gaaaagctat tggaaagagc taggaaaata tccttggaga 6961 tattaaaggg ggtaaaggag atagatcttt caatagactg gacaaccaag acgtggtatg 7021 ggaaaccagt gaaagggagc tctgaaaaag gaaactcgtg gaactacgca acaaccaagt 7081 ataaggggaa agtactttta cttgccttta ttccgcaagt gaacggtatg actaaggacg 7141 agatagtgaa ggttcttgtg gagcaagtaa tggcaatggg attcaagata aggttgatga 7201 ctcttgacgc tggtttctac acagttgatg tgctcaattt catttcacag tttaagtata 7261 tagttgctgt gcctgttggg gatgttaagg tttatgagga gtttgacgga gagtatatga 7321 caaatagtaa gaggcatagg agggatgggc aggtcaagtt caggctcctc gtgtacagca 7381 aggaaaaagt gaggagaaag agtcttgttt attttgctag ggctactaat ctagacctat 7441 ccaagaggga agtgttggat ttgtacaata aggtaagagg tcccatagag acctcttata 7501 ggaacattaa ggcttttctt ccatttactg gttctactaa gtttgttttt cgcacgttga 7561 tcttcgtgct ggcccttgta ctctactcct tatataccat attcaagggg gaggtgggga 7621 gagaggagtt tagattatta ttaattcttt tatttcctga tttattcaat ccagagaatt 7681 ttacatttaa tataattgaa acacttattt acactataga tttattttta aggaggtgat 7741 tttgggtcta ccgtgttagg agaggacgta acgtattggg gggcagtgtt tggatttaca 7801 atgggtttat ttgagaagtt cgatagaaaa agggttttcg acacgccaat agcagagcaa 7861 acttttatgg gaatggcagt aggcgcagca gctgctggct tacatccagt agtttccttg 7921 atgttcgttg atttcttagg agctggattc gatcaaatgt acaaccatat ggccaaaaat 7981 tactatatga gtggtggaca attcccaatg ccagtaacta taataacagc aataggagga 8041 gggtatggag attcatctca gcattctcaa gtgttataca gtttgtttgc ccacttacct 8101 ggatttaagg ttgtagtacc atcaacgcca tacgatgcta aaggtttagt aactaaggcg 8161 ttaagggatc caaatcccat cgtagtgttt gggcataaat tattaactgg attaccgttc 8221 ttaccctttg agggtacaga ggaggaagtc ccagatgagc cttatgaggt tgagtttggt 8281 aaggctgctt taagaagaga aggtaatgac ttaacaataa tttccgcagg attaatggtt 8341 cataggagtt tgagggctgc tgaaatgctt caacaggatg gaatttcggc tgaggtaatt 8401 gatttaagaa cattaatacc tttagatgag gagactatag ttaagtctgc aaagaaaact 8461 ggaagggttt tgatagtgga tgaggattat atgagttatg gaatgacggg agaagtagcg 8521 tttagaatcc aagctaaagc attaaaggac cttaaggtac caattggtag gttagcagtt 8581 ccagatgttc caataccctt ctctgaacca ttagagaacg ctgtaatacc tagtattaag 8641 agaatatata atgaggcgag gaagttatat cagggaagtt aacgttaatc attctttttc 8701 ttttaaaaaa cttttatagt attaagttca atataaatag tagtgggaaa gcaagtgcta 8761 tcatatgagt atatattaag agtagatgaa aagggaagga ttatgattcc aaaagaagta 8821 agggataagc taaagatttt caattcagtt agactaattg taaatgagag tggtgaaatt 8881 attataaaga aaatggagag aaatatagag aaatatgctg gatattttag agttgactgg 8941 agtaaacttg caggaatgga tatcgataaa atattggatg aggcgttgag agagaggagt 9001 gaaaagtggt taagagatat tttgacgtga acgttttctt atattttcta actaatcatc 9061 ctaattattt tcaaagggca aaagaatggt ttcaaaatac aaatgaaatt tacacaggag 9121 aaattaccat tatcaattaa ttgtaatatt gaaaaagcta acaggtaaaa gcgatgagga 9181 aatattaaac gtgttatctt ctttcttccg agacgccgaa ataaatttag atcacttaga 9241 gactagtgat ttggaaaagg taagagaaat cgtggaaaag ttcaaattgg actttgaaga 9301 cgcaatacat ttcttttatc gcaaaagatt ggtgagttaa ttagcaatga taggaatatg 9361 caaagaattg gcgctagatt ctagccatga tgaaaaataa tttaattttg atttcacgtt 9421 aataatagat gatttacgta tttaaaggct tatcgggtta cattatcctt tttctcctca 9481 tgattggtga gggattagga ctgcctttac ctagtgaagt tataatgccg ttggtaggtt 9541 attattcata cttgggtagt atatccttat atatagctat aatagtaggt actttgggta 9601 gtctagttgg ctctataata gcatacgtaa taggttataa tctaggctta ccattcctaa 9661 agagatatgg gaagtacatt ttaatagatg agggtaaaat agaggcgtta cataattggt 9721 ttttgagata tggtgatatt gctgtatttg gatttaggtt cgtaccggga ttgagggctc 9781 tcatatcgta tcctgcgggg atagggcaaa tgaaaattcc taaatttcta ggatttactt 9841 ttttggggca cactatttgg gacattgtgc tttccctagt aggttacgag ttagctaacc 9901 agattaattt tgttgtaaca ctagctgaga aatttgggaa ctatatacta atcgttgtag 9961 ttataataat tgtaatttat attctggtaa gagtattacg caatagacag taaacttaaa 10021 ttattttaat ttattaataa attaagttaa tcttttacat aaaagttttt atatatgttc 10081 ctataagtta attgttaggt gataaatatg gcgaaatcta ctaccacaaa ggttggaagt 10141 gcaataggaa gaacgatagt ttatataatt ctttatgtca ctgtaagcgc gatagttaag 10201 ttcctaattg aggtgttatt accatcagtt cacttaaacg ccgtgagtta tgaatcgtac 10261 atacagatat tattggcact ggcatttggt tacctaattg tctccggaat ttctctaata 10321 ttctattatt ccctattgcc aaagtacggt catccaacag ctactgcggt aaggaatgtt 10381 atgagaatta ttggaattgg ggcactagta gctgcgatag caggtgcagt agctggtgga 10441 gcagccggtg ttgcattggg cggtttcata ggtatagtaa taggctttgc atcacaacaa 10501 gtattgggtc aagcagtcgc tggaatgttc ctattaatag ctagaccgtt taagataaat 10561 gataatgtta atctagtggg cgaagatgga atagttgagg atgttagtac gttatttacg 10621 actgtcataa aatcggatgg gactaaggta ctcataccca ataacgccat aatagggaat 10681 aagatttatt tgaaacctgt tcaacaacag caaaagagtt cttagtttaa aacttggaaa 10741 aataattttt ctcaatttta gtatcttttg tattataatt ccctctatta ttgaaactac 10801 tattttagct ttcatgaaac cgtagaacag atcatcagtt atattgcagt ttaaaaggag 10861 tcgtagcggg atttgaactc gggacctctg cccttaccag gacttatgta gttacattcc 10921 ttcattctat acaacatgtt catgttacac ctgagtatat ttaaaccata aacgccattg 10981 tataacatta gtaaaataac tcatataatt tgttattact cactttggca aagctttccc 11041 cccaaacttg tgtatagctt gtcatatgcg acaaactaaa atgtaagaaa tttgtcatat 11101 gtaacaaatt tatattagca gaagaattat actatattat gaatgatgag gaactcctta 11161 agataatgtc agagtggaac ttttggggaa aggaaaaacc caaagtagga atagagaggg 11221 aatgttatgt agagagaata ataaaactat taaatagcgt gaaagtcata gctatttctg 11281 gggttagaag agctggaaaa tcctttattg taagagaagt attaaacaga ctaataaata 11341 atggagtaaa cccagaagac actttgatta taaggctcga tgacgaaaga ttgttaaacc 11401 ttaactatga gttacttctg aagatatata acctttatct aacttacgta aaaaaagata 11461 agagtaaacc aacttatcta gtgcttgatg aagctcaaga ggttgaaggt tgggaaaggt 11521 tcgttagagg tttagaagaa agatgcgaag ctaaaatagt tgttacggga tcatcagcaa 11581 aactgttaag ctcggaattt acaaccctac tttccggtag gcatgttgaa gttagagtta 11641 ctcctctatc tttccttgaa gtgctggaat ttaaagggat aaaaataaaa ggtgtgctgg 11701 aactcgctga aaacatagat aggataggga aagaattggt agaagtgatg aattatggtg 11761 gatttccgga tgttgtgctt aatcccgaag tgagggctga gctcgttcat tcttattttg 11821 acactattat tgtaaaagat gtcgttaata ggtataagct tagaagggag gataagataa 11881 ggactcttgc aaagttctac gtttcttcat ctgcctctaa aataacttac aatagcgtat 11941 caaagttcct taaaatccca gtaaagaccg ttgagaggta ttcagaatat cttgaaaagt 12001 cgtttctggt ctttttccta aaaaactatt cgatatctcc aaaggcggta gagaattcac 12061 ctaggaaggt ttacgtaata gacaacggct ttctgaagta cttttctact gcatctctcg 12121 ggagaatatt tgaaacactg atagttcaac atctgtatag atatgcggta agaagatttt 12181 atgaactgta ctattggtct tctgaggact cggaaattga cgttatttta aagagcggaa 12241 agaagattct gcctatacag ataacttatg aactaaatga tgaaaatgag gagagggagt 12301 taaagagttt aaagaagttt aagaaatatg ctaattatga taattcgctt gtgattacgt 12361 ttgagcagga gatagagata gaaggaatta aagttctccc cgcatataag ttccttttga 12421 atctggagga tttgttggac tctttgataa gctgacattt ggaaaaaaca gagaatgata 12481 gtctttttta tacttgctca agttataaag ggaaaggtaa aattggataa tgatcacgta 12541 tgagctcata acttatgagt tgacttatac tgatgttaac ctttaaagtc tgaggaagta 12601 aaatataagt ttaatcttaa tgcaataaca tacttagaat tagataaaat tgaggtctaa 12661 gaactttccg gcgttcagta ataaatattt cggttgaact tcaagcatag tgtcaactaa 12721 gattgccacg tgaattgaaa ggattcacgt ggcgattttg ggtcacttgg gctcataagg 12781 cttattatta taccaaacgc tccacacaac cttagccaac tttctcgcca aggcagtgta 12841 taacttccta ccgtgaagct tatccttgtg agactcgtaa aacctcaata aggtcgggtt 12901 ctttgaacag ttcatctgcg caagaaagta gaaaaggctg cgcaaatact tgttacccct 12961 ccttgagatt cccttactta ccaccgcctt accgctcctc tccactaccg gatctagacc 13021 gcaataagct acgaaagact caggcttagg gaagcgccta atatcaccta caacgccaat 13081 gattatccct gcagcaagct tcccaactcc cggaatcgtc agtaggacgt ggtcttccgg 13141 tacttggctc tctatcatct ccttgacctc ttttaacttc tcttgcgtct caaagagggc 13201 cttagccagt attttgactt cttcaagtac tattggcgtg tattcaagtt ggtagagtac 13261 ttcttgtgcg aagtctccgc ttgctagtct ttccaatctc tccttgttta tcttgtcgtt 13321 gtcgcttact aggaatagtg ctctctttag tctgttcttt tgttttactt ccatgtcctt 13381 taagaacagg tatagagtta cgagttctct aaggacgtta tactcgtact cctttgcctt 13441 gtcgaccatg ttttctaatt tttctgcgtc gtaaaaatct gttttctttt ccctgaagtc 13501 cttttccctt gatagcacgt ttgggcttac ttgtagtact cttattcctt tttccttgaa 13561 gtattgggaa ggctttattg agtatactcc ggtgggctct aggactatcg tgcaaggctt 13621 catatcgagg attttctcat agccttttag gttgttctcg tattttcctc ccctgctcgt 13681 gattaaatta tcttttgaca cgtctattcc taggacccct acctccttgt cacacctata 13741 tgggtggatt ttcccacaat gttcagtccg acagtagggg tcggtcacgc cggaaaccga 13801 agacttagct tcagaaatac taccgaccat actcccaacc ctaggagtat tactctttac 13861 tctctagagc taataaaacc tatataggta ttcagtgaga gagaggaaaa ttgattattg 13921 ataacttgat ccggtattat tgaaaaagtc tttaaagtac cgttatagta ataaacgtaa 13981 agttggtttg aagcgggtaa gtaccagaac cctaaaccta tttgttgccc aacactgatt 14041 gagcccacag acacgtttaa ctgtttcaca ccgtcaaagt atacgaatat tctatacgtt 14101 gggaaactcc ctttttccag ataaactaca atcccatcag aggcgtaagg taatgcggat 14161 gcatagctac ccgtaaaccc tgaagggaaa tttacaccgt agcctatggc gattgaaccg 14221 taggatcccg tattgcttga ggacgccaat aaccatgtga cgtttagagc gatttgtgat 14281 gatgaaagag aaagagatac gttatttgaa atgtactctt ggttcggcaa aacttgaagg 14341 tagtaagtgt tgtatatcga aacgtaagtt gggttaagcc atggaaggtt cagcaaacta 14401 gaacccgttt ggctcactgt aacgagttgt gtagaagatg gctgaacaac aatattctct 14461 gagtacgtag agtagctagc cccaccaccc caaccgaaac gtgctattaa tccgtttgtt 14521 ggtaagaaga agataggtaa gagtaagagg gttagtagta gtaaagatgg gccccacttc 14581 attaagcgat aaaaaattat gtggctttat aaagggctaa actacttccg agtgtagcgg 14641 cgtattttgc ttatcaaacc attcctaagc tcaggtgaaa agtaaaaagt taacacagta 14701 gctacaatac ccgccactat aatgaactct ggtatatatt gtacatacca tggtggtggt 14761 ggttgattta ctactattgc gggttgttga gatatttgaa ctgagggtga gggtgggggt 14821 gagatgcata aagaaggaaa gtaaatcttc ataatccatc taatttaaaa aggaaaaaag 14881 caataaaaaa gattttcctt atagcccata tgtagtttga ccagctcccg gatagtaaaa 14941 ttggtatagg taatcccatc cgccattatt attagcccat ccgttatata tctgagcctg 15001 agctacattg taagttgatg gttcgttaag agtataaacg tctgcataca tattacctac 15061 gggattatta ctaggcccaa tatgctcatt gccatcagaa ccgacatatg agaaagtgaa 15121 gtggatcatt ccaccagata catatggtaa ctcagcataa ggcccggaag ttgaaaatga 15181 aggtgcttcg actatactca tggctgaacc cgtattagtc catggtattg atgtatatat 15241 tgttgtagtc caataagtcc cattggcgta atatacgtag agttgagcta gcgctgtgcc 15301 gtttccaaga ttttctaaga acacatccaa ataagttgct tttccggcgg ggacatagtt 15361 ttcattatta tatacaagtt gtccatttac aatagtcgtc acaaaataat taactgatac 15421 atatgatccc acatcaatat caaaccccgc ctgaataaag ttagtctgtt ctgaaccaga 15481 tgaagaatcg gtaccgtatc ctatttgtgc gggacttaac ccaatccata tacttatatc 15541 ttcagtatat atgtagtttg ggtaagaaat gtaacctaac gtaaggtttc caacatatat 15601 actttcacta gcccacagta tgggccccca gtagtttgta aaccacgatt tccattcaac 15661 agagtaagct acaccagccc aattgtctga gttataagta tttactattt gacttgcacc 15721 tatctgactt gcagttatgg caccggtagg tgttgccaat attagtaact ctatggatag 15781 ggttagaagg gctagaaggg ccttcctcat tgtaagcgaa aaaagaatgt agactttata 15841 aagagcttaa aacggtgggg cgtagttaaa gagaaggata aatgtgtttt gtgtgtctat 15901 cagtatcgac aacacgacaa acggtagtaa tgaaagccac ttatacttac ttacttttaa 15961 taggtcgaaa agtcctgtat accagtagac tccggtgaaa aatagaagtt ttactgatat 16021 cagcattagt aacgctaaga taaacgagat gtggccttca taataataat agaaccagat 16081 aaagtagttc tcttcaaaga ttgcgttctc tttcaaccaa tatattgcag atattatgac 16141 gtcataaaca tttagtagga tgaagagaat ccatactatt ttaaggattc tcatcaacat 16201 cacctaacta acgcagatat tatgtttttt gcaaacatgg tctaagagtg cgtcagtctt 16261 tgcaaactcc ttaccgcaca ccgggcaagt ctttgcgtgt tccgtataac ggatgtgttg 16321 tttcagacta actgaggaac taaggggcat caaacagagg ggataaacgt aaggcgagac 16381 tgctttactc gtcagtaact tatagagata aataataaga aattcccgcc gggcgtatat 16441 tatctaattc gcaaaaatgg gcgtatgata ttggtcgtga agaaaatttg aattttttat 16501 attaatgaga aattttgcct tccactttca attcgtcgcg tttttacggc aaaaatttac 16561 gggttgtcaa tacttataaa catgtttttg gcaaccataa tactcgaggc gaaatgatag 16621 aaaaacaacg tagatataaa ttcgacgatt atctcttgag ggaaagaaaa ggtcggtatt 16681 atgtttacaa gctagagtat gaaaacggtg acacaaagga aacttacgtt ggtcctttag 16741 cggacgttgc tgaaaagcat attaaattga aagatgaaat tgggggtgtg gggtaccccc 16801 acaaagccgc ggccgggatt tgaacccggg acctctgcct taccagggct aaataaggag 16861 gccgaacgtc gtaaaatatc gttagttgcc aatttacgtc agtatgcgac ggaaggcaac 16921 ttaaacgcct tccgtgaata tctcttaaat gagaagaagc tcgatgagac tacagtgcaa 16981 acacgtttgc tttatttaaa gccggggaag aaaatagttt tcaataatca aagcgttaag 17041 tcgtaccgtg cgttcgcaaa gttcttagcg ttacgcggct taataagcga aaatttcgca 17101 aacgaaatat tgaaagagtt gaagagtgta aggacgcaaa gcgatttaag agtcccaaca 17161 ttagacgatg taaaacgtac actgcattta gcgaaagaat atagtgaaaa cgtttatttc 17221 gtttatcgta tcgctctgga aagcggaagt aggctttccg agattttatg cgtacttaaa 17281 gacccgagtc aagacgtttg tgattccggg atctgttatt atcccctggc atggcaacgc 17341 ggatataagg gcgttttcta cgtcttccat ataacgccgt tacgcaaagt cgacattacg 17401 agatacgcta tagctgattt cgaaaggcgt cgagacgcga tagcgataaa atacttccgc 17461 aaattcgtcg caacgaagat ggccgaactt tcgatacctc tcgacattat cgattttatc 17521 cagggtagaa agcctacccg cgtattaact caacactacg tttcactttt cggcatagcg 17581 aaagaacatt accgcaaata tgcagagtgg ttgtccaaaa tggaacatat ggcgtaagat 17641 tttgatgggt ttaaggtggt tgtaggatcc ccgtcaccac ctctttcttt atgcctaccc 17701 cacgggagcc acacgtgctt tttgcctata tggtctaata ggccatcagt gtttgcaaac 17761 gttttcccgc aatacctaca cgtcttctct ttttcctcat accttaaatg cataatgaaa 17821 gcctggtatg tttcgaaagg agttaagcaa ataggacaga cccatttata caccgccctg 17881 agtgaaacgt aaagcat //