LOCUS NC_012125:26 18435 bp DNA linear BCT 10-SEP-2013 DEFINITION Salmonella enterica subsp. enterica serovar Paratyphi C strain ACCESSION NC_012125 SOURCE Salmonella enterica subsp. enterica serovar Paratyphi C strain COMMENT locus start: 4559990; locus end: 4578424 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.547730; n0_4mer:D = 35.655804; n0_4mer:PS = 35.253990 FEATURES Location/Qualifiers source 1..18435 /organism="Salmonella enterica subsp. enterica serovar Paratyphi C strain" gene complement(1..1971) /gene="vexE" /locus_tag="vexE" /db_xref="4559990..4561960" CDS complement(1..1971) /gene="vexE" /product="Vi polysaccharide export protein" /translation="MSLHSTFKKISPTTLLKQEDWEGLCLYFSQHPEKVRDSAGNEQN IILFAIACLRKDETDVGLTLLSDRVLTAKNGRDLLRRWVISPLASSQPDAVLQVVNKL LAVNVCQPEDVLLVASVLLKSKQYATVADLAEQAWLAFSGNSQIFALHLRTLVLMDKE LQAISLARTQAQEVPPRGDMIATCLSFLNKSRLPEDHDLARALLPFFALERQESAGLA VDTLCAVGKYQEAIQTGESALARGLDGAALRRSLGLAYYQSGRSREAKLQAAEHWRHA LQFNSDNVRIVTLYADALIRTGQNEKAIPLLQQSLATHPDLPYVRAMYARALRQVGQY TAASDEFVQLAREKGVTSKWNRYAAAALLQAGKTSEAESVFEHYIQARASHLPQSFEE GLLALDGQISAVNLPPERLDWAWEVAGRQSGIERDEWERRAKWGYLADNFLLDWLECR GEQADEPMYRLADISHVEQFFQRLQLDQRGCIIVSAHLGAMYAGPMILSLLEMNSKWV ASTPGVLKGGYGERLISVSDKSEADVVRACMQTLHSGQSLVVAIDGALNLSAPTIDFF GQQITYSTFCSRLAWKMHLPTVFSVPIWKNRHIHFVLERMVDPLKFESQLSFTERWKE NYLQCVTRILQSDPENLRLSGGIWRNIIRRDS" gene complement(1991..3295) /gene="vexD" /locus_tag="vexD" /db_xref="4561980..4563284" CDS complement(1991..3295) /gene="vexD" /product="Vi polysaccharide export inner-membrane protein" /translation="VENSERIKKWKEERAKVAQESRASRLQQKEDERALRQTEKSADA KSHHNPDAGWSATDADSVRRASLVIKERRVQQAKQSLRRLFLYIALPLLVIMLMSWIL TSHFYSADATFIVQTDASQDNFSGTSFFGAGNKMSEGFQVREFILSKEMMDRMEKELG FLSYFAQDDIALFSRFHAPLGINDDPYRYYLSKVSVAVDIQQGMLRLNVKARSAKQAE FFAQRILSFAEQHVNTVSARMQKERILWLENDVKSAQENLGAARLELLKIQHIQKDID PKETITAIYQLIAGFETQLAEAKAEYAQLMVNGLDQNPLIPRLSAKIKVLEKQIGEQR NRLSNKLGSQGSSESLSLFEDLRLQSEIAKARWESALQTLQQGKLQALRERQYLLIIS QPMAESDTTRYADGTKWLLFFVLLGITYLVTSLLITIRRMRE" gene complement(3318..3959) /gene="vexC" /locus_tag="vexC" /db_xref="4563307..4563948" CDS complement(3318..3959) /gene="vexC" /product="Vi polysaccharide export ATP-binding protein" /translation="VVLDKTDFVMGYHEHIGILAAPGSGKTTLTRLLCGLDAPDEGDF IGLRGDALPLGANSFILPGLTGEENARMMASLYGLDGDEFSHFCYQLTQLEQCYTDRV SEYSVTMKTHLAFAINLLLPCRLYIADGKLYTGDNATQLRMQAALACQLQQKGLIVLT HNPRLIKEHCHAFGVLLHGKITMCEDLAQATALFEQYQSNQATIQTEDYSFDI" gene complement(4039..4833) /gene="vexB" /locus_tag="vexB" /db_xref="4564028..4564822" CDS complement(4039..4833) /gene="vexB" /product="Vi polysaccharide export inner-membrane protein" /translation="MNILKNNSYYFMKLITVCELIILLMSRDIKTRYNGNLLNYMMVL AVPLVWISITVISFQYLNRSVPISTDDISFVIAGILPYLLFRYTITATMRTHSFSTSL AVVSQVKKRHVIFSLAAVEFVNAVIIYIIISLINFLIFSRWEAQKPFLIFEGMVIAWL LGLSFGYFCDALSERFPLVYKAVPVMLRPMFLISAVFYTANELPYSLLSIFSWNPLLH ANEIVREGMFEGYHSLYLEPFYPLAFSATLFLAGLIFHLICDTENH" gene complement(4843..5910) /gene="vexA" /locus_tag="vexA" /db_xref="4564832..4565899" CDS complement(4843..5910) /gene="vexA" /product="Vi polysaccharide export protein" /translation="MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPT LKLSAPDTVPKTIVDPVFAANNWHWTSLAKGDVLHITILSSGGAGYLSNNASGDRADF ENILVTDSNTVQVPYAGTIPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMV TVEGSGKTGRYPLEQSMNRLSHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQ YPGLDIALQPDDRITLRQVTEYVNVLGAAGVQGKYALVQRHSSVVDALALAKGLNDNL ADPQAIFLYKHNEAEQAKQQMRKLNIYHVDMSQPNSVFLAQAIRVDNGDVIYISNASL TDFAKVKAAFDSFLTRGTNSF" gene complement(5955..7691) /gene="tviE" /locus_tag="tviE" /db_xref="4565944..4567680" CDS complement(5955..7691) /gene="tviE" /product="Vi polysaccharide biosynthesis protein TviE" /translation="MITQEEKLAALGKTCLTLKQEKKLAQAVALIDSELPTEALTSLA MLKKAEFLHDVNETERAYALYETLIAQNNDEARYEYARRLYNTGLAKDAQLILKKVSN GVQKKYNNYLGKINKICDLLERLEGKAIPVGTNTCIIAMKHAILFYRNRQPRQLPVGS FGRLALCTGSLGSGGAERQISRLAIEIARKYRQKGKIGGLKVEEPVELIIRSLTPELR QDFFLKEVLEEQVEVLEIAKITGNLFDDATIESPELRLLLSHLPPVCNYGIKHLVPHL CERKLDYLSVWQDGACLMIALAALIAGVPRIQLGLRGLPPVVRKRLFKPEYEPLYQAL AVVPGVDFMSNNHCVTRHYADWLKLEAKHFQVVYNGVLPPSTEPSSEVPHKIWQQFTQ KTQDADTTIGGVFRFVGDKNPFAWIDFAARYLQHHPATRFVLVGDGDLRAEAQKRAEQ LGILERILFVGVSRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTPAGGSA ECFIEGVSGFILDDAQTVNLDQACRYAEKLVNLWRSRTGICQQTQSFLQERFTVEHMV GTFVKTIASQPR" gene complement(7691..10186) /gene="tviD" /locus_tag="tviD" /db_xref="4567680..4570175" CDS complement(7691..10186) /gene="tviD" /product="Vi polysaccharide biosynthesis protein" /translation="MNLMKSSRMFTLTAIGSCRIVSPVKRAQPYFNFQANFKRIYGFT HTSSEALQQIRFILGLIDIPEKVRPFIFRPNVNYSNTDVHSRSDFYIIEISSQKKIMA YGFCLQINYLTRHFYEFFSQTERACMYWSLATQGNQHKLLAYLKDDPCFAGMSEDDRA LLSNINVEQMDEHAIEQDMMEIVQLLGRDRVMFMTHVDAVTRAGTVILSRSRLIKNVD TIAARMDIPCVNPTNLMGKWGQKRALEKNGDDLTHYTDMFGDAIVAAIFKGVINNTNH HLDEGRQEKQDQIREITLSITKQLADGDIIAASQQLFAALRNQQQEPVLIQLRSVIFS HLGYYEQAYQDISDVEKIIGTTDSTLRCRLRSLHGLARWREALSTAEMMLSNEIEDEE VLTVAAGSADALQLFDKSYHYWKRVLLLNPETQSGWVNFLSSTQYFNDGNAFSEAFHA GIQSQRLNDTFMETALSLAIKFSDELIFMHALEQLLRHESEFALTVLSTIHDTGLVIR TAFCIKNMSYHQALRTSYKDKIHDVFEAWNNTALSLHSVDDFVSLSTSLAYSYSAFMV YPHSRISRFNNEVKMAWRDKLREMYEREDYENILAGAKIVWPLLKFDPVSTVYCARTL VNLGAWKDACTLAHMTLIRNSNITSLQSIMLRSIRHINNIPFLIDLIANVMSITLSFQ NASMNKLFEKECRNVATRALKYVRQKKTEGRLNEALSVLISLKRIEPDVSRLMREYKQ IIRLFNESRKDGGSTITSYEHLDYAKKLLVFDSENAYALKYAALNAMHLRDYTQALQY WQRLEKVNGPTEPVTRQISTCITALQKNTSGKS" gene complement(10210..11256) /gene="tviC" /locus_tag="tviC" /db_xref="4570199..4571245" CDS complement(10210..11256) /gene="tviC" /product="Vi polysaccharide biosynthesis protein, epimerase" /translation="MTAYEELRTKLVLAPKRWLITGVAGFIGSGLLEELLFLNQTVIG LDNFSTGYQHNLDDVRTSVSEEQWSRFIFIQGDIRKFTDCQKACKNVDYVLHQAALGS VPRSLKDPIATNSANIDGFLNMLTAARDAHVSSFTYAASSSTYGDHPDLPKIEERIGR PLSPYAVTKYVNELYADVFARSYEFNAIGLRYFNVFGRRQNPNGAYSAVIPRWILSLL KDEPIYINGDGSTSRDFCYIENVIQANLLSATTNDLASKNKVYNVAVGDRTSLNELYY LIRDGLNLWRNEQSRAEPIYKDFRDGDVKHSQADITKIKTFLSYEPEFDIKEGLKQTL KWYIDKHSTLYSSV" gene complement(11259..12536) /gene="tviB" /locus_tag="tviB" /db_xref="4571248..4572525" CDS complement(11259..12536) /gene="tviB" /product="Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase" /translation="VFGIDEVKIAIIGLGYVGLPLAVEFGKSRQVVGFDVNKKRILEL KNGVDVNLETTEEELREARYLKFTSEIEKIKECNFYIITVPTPINTYKQPDLTPLIKA SETVGTVLNRGDIVVYESTVYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGD KKHRLTNIKKITSGSTAQIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLN IALVNELAIIFNRLNIDTEAVLRAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKSQGI GYYPEIILAGRRLNDNMGNYVSEQLIKAMIKKGINVEGSSVLILGFTFKENCPDIRNT RIIDVVKELGKYSCKVDIFDPWVDAEEVRREYGIIPVSEVKSSHYDAIIVAVGHQQFK QMGSEDIRGFGKDKHVLYDLKYVLPAEQSDVRL" gene complement(12781..13212) /gene="tviA" /locus_tag="tviA" /db_xref="4572770..4573201" CDS complement(12781..13212) /gene="tviA" /product="Vi polysaccharide biosynthesis protein" /translation="VNLNRYSLLNALNFFTRMSDINKIIVIISSSRLMPLARFWLTEC KNVIAVFDAATSVQDIIRNVSQHQSGEKILTEQRDYRFRINRKDIVKMKYFLSESGME ELQDRFMNSSSTMYRWRKELAVKFGVREPRYLLLPDSVTLL" gene 13860..14048 /gene="" /locus_tag="" /db_xref="4573849..4574037" CDS 13860..14048 /gene="" /product="hypothetical protein" /translation="MTGKPSERHTGFIISGEMMVRDCFGNEYLIHAGEAFEVSENHDA WVVGDTPCVALDFTHFLR" gene 14173..15684 /gene="" /locus_tag="" /db_xref="4574162..4575673" CDS 14173..15684 /gene="" /product="DNA helicase" /translation="MPHTDTPEQAAVIAWKGERLVVCAFAGSGKTTTLRRYAEENPTE RMLYIAYNRAIRDEAEQKFPFNVTCKTSHQLAWPTVGKHYSHRLINSLRLTYVARALN SRNWLLARLTLDVLNRFICSAATDITPEHMPDPDDCKGLQPGQILFSAKKIWAMMSAR QGDFPVTHDTYLKLYQLSKPNLSSRYTTLLFDEAQDANPVISAIVLNQTCRVVLVGDT HQQIYRFRGADNAMQAPQLENSDRLWLTHSFRFGPEVAGVANRLLALKGETHQITGKG GAGRVLLTMPRNFGHHAVLHRSVCGVIRTALHWSLAGRKVFWVGGMESYRIEDLLDLY WFSIDMSERMRHDRLTREYRDYDEYLQIAEDTGDVEMKQGIFILEQFFPLPDRLNTLR EQRVISESEADVTVCTAHRSKGLEWDRVKLHDDFLDILDPDMPESQRQDEINLMYVAA TRARKVLITDPILHELLIQPRAEDIAGTSADKSGESEVSTENDKKGTEYVPES" gene 15692..17257 /gene="" /locus_tag="" /db_xref="4575681..4577246" CDS 15692..17257 /gene="" /product="hypothetical protein" /translation="MEKKNFRQIEENKSGNAKKRLIPCTDGYFNPAAISDLLQHERRQ QWLRILWENSALPKERFERYFLLPLHGVVGLCQRLPASAQGKFAYTDGMVDYVIQTTV FAVRLSKGYMLPRGASAEEQSAQSVSWSAVVYYAALFHSLGRLWNIEGELRSGAVWRP GLSVPEEPYRFRFKAEPDIAGAQVYGELIALRFLPEPVLQWLGKNPDILRTLLAFISG RYSDAMDITDIVNEAIVHAGGIPLGFPIAQEEQTSELAEILNPAATVAPVLRKGSSTT PPDVPVMVDGGQETTVLLSSLDSDAKPERGEGQPTAETDPDVLQVMSILGGLTNTDTQ SPEKEGVNTETDMVAGESFPEVAVALETSAAEEVINDTVTTECTGSSSGGISSLSSTE LGDLFWSWLRDGLREGDIPVNTADACVHLTCGFVFISVPGVFFLFLKSHSRSCSSGLK ESGRKEQVQAAFEKMRKHRVSDSRRFWQCCLYEEPGGRGRYKKLTGYLIKMSEIYANG NFPDDSLFLKVIN" gene 17421..18435 /gene="" /locus_tag="" /db_xref="4577410..4578424" ORIGIN 1 ttaactatcc ctacgtataa tgtttcgcca aatcccaccg gaaagacgca gattttccgg 61 atcgctttgc aggatccggg taacacactg cagataattc tccttccaac gttcggtaaa 121 tgaaagctgg ctttcaaatt tcagcggatc gaccatcctc tcaagcacaa aatggatatg 181 cctgtttttc catatcggaa cactgaaaac ggtaggcaaa tgcattttcc aggcaagacg 241 agagcaaaat gtggagtagg tgatttgctg accgaaaaag tcgatagtcg gcgcactcaa 301 attcagcgcg ccgtctattg ccaccacaag cgactgtcca ctatgtaagg tctgcataca 361 ggccctgacc acgtccgctt cgcttttatc gctaaccgaa atcaatcgct cgccgtagcc 421 ccctttgagc acgccaggag tggaagccac ccatttgctg ttcatctcca gtaaggacag 481 gatcatcggc ccggcataca ttgcgcccag atgagccgat acaataatgc agcctctctg 541 atcgagttgt agccgttgga aaaactgttc gacatgcgat atgtcggcca atcggtacat 601 aggttcatca gcctgctctc cccgacattc aagccagtcg aggagaaaat tatcagcaag 661 atagccccac ttcgcccggc gttcccattc gtcgcgctcg ataccggact gtctgccggc 721 aacttcccat gcccagtcaa ggcgctcagg cggtagatta acggcagata tttgcccatc 781 aagcgccagc agcccctctt cgaatgattg aggcagatga cttgctctgg cctgaatata 841 gtgctcaaag acgctttccg cttcgcttgt tttccccgcc tgtaacaatg ccgccgcggc 901 ataacggttc catttactcg tcaccccttt ttcccttgcc agttgtacaa actcatcgct 961 ggcagcagtg tattgcccaa cctggcgcag tgctcgggca tacattgctc tgacataagg 1021 aagatcagga tgagtcgcga gcgactgctg cagtaacgga atggctttct cattctgacc 1081 cgttctgatt aaggcatcgg catacagggt cacgatacgt acattatcag agttaaattg 1141 cagggcatga cgccaatgct cagcggcctg aagcttcgct tcccgactgc gaccggattg 1201 atagtaagca agccccaggc tacgacgcag tgctgcacca tccaacccac gggctaatgc 1261 ggattcccct gtctgaatgg cttcctgata tttaccgaca gcgcacagcg tatcaaccgc 1321 cagccccgcc gactcctgcc tttctaacgc gaagaaaggg agcaatgcgc gggccaggtc 1381 atgatcttct ggtaggcggc ttttatttaa gaaactgagg caggtcgcaa tcatatctcc 1441 ccgtggggga acttcctgcg cctgtgttct ggccaacgag attgcctgta actctttatc 1501 catcagtacc agtgtgcgca aatggagggc aaaaatttgg ctatttcccg aaaaagcgag 1561 ccatgcctgc tcggctaagt cagcaacagt cgcatattgt ttactcttaa gcagcacgct 1621 cgcgaccagc aggacatcct ccggctggca cacattcacc gccagcagtt tattaactac 1681 ctgtagtaca gcgtccggtt gagatgatgc cagtggcgaa ataacccagc gtcgtaataa 1741 atcacggcca ttctttgccg tcagcacacg gtcagacaac aaagtcagcc cgacatctgt 1801 ttcatcttta cgcaaacacg cgatagcgaa gagaataatg ttttgctcat ttccagcact 1861 atctcgcact ttttcgggat gctgactgaa atagaggcat agcccctccc aatcctcttg 1921 tttgagtagg gtggttggcg atattttttt aaatgtagag tgcaagctca ttatatttcc 1981 ttactcagcc ttattcacgc atccgcctga tggttatcag gagagaagtc accaggtacg 2041 tgatgcccag caacacgaag aacagtaacc actttgttcc atcggcatag cgagtggtgt 2101 cagactcagc catcggttga gaaatgatca gcaaatactg tctctcacgt agagcttgaa 2161 gcttcccttg ctgtaaggtc tgtaaggcag attcccagcg tgctttggcg atctcgctct 2221 gcaggcgaag atcttcaaat aaggacaggc tttctgaaga gccttgcgac cctaacttat 2281 ttgacaagcg gttacgttgt tcgccgatct gcttttccag taccttgatt ttggccgaca 2341 ggcgaggaat aagggggttc tgatccaaac cattcaccat taattgcgcg tattccgctt 2401 tcgcctccgc caactgcgtt tcaaagccag caattaattg ataaatagcg gttatggttt 2461 ccttcgggtc aatatctttt tgtatatgct gtatttttag caattcaagt cgagctgccc 2521 ccagattctc ttgggccgat ttaacatcat tttccagcca caaaatccgt tccttctgca 2581 tccgcgctga aacggtatta acgtgctgtt cagcaaaaga cagaatgcgc tgggcaaaaa 2641 actcagcctg tttcgcactc cgtgccttca cgtttaaacg cagcatgccc tgttgaatat 2701 cgacagcaac cgagactttt gataaatagt aacgataagg atcatcatta atacccagcg 2761 gcgcgtggaa gcgggaaaat aatgcgatat cgtcttgcgc gaaataagat aaaaaaccga 2821 gctctttttc catccgatcc atcatttctt tcgaaagtat aaactcgcga acctgaaagc 2881 cctccgacat cttattgcct gcaccaaaga aagatgttcc agaaaaatta tcctggctgg 2941 catcagtttg cacaataaag gtggcatccg cactataaaa atgcgatgtt aaaatccacg 3001 acataagcat aataaccagc agcggcaaag caatataaag aaagagccga cgtagcgatt 3061 gcttggcttg ctgaacacgt cgctctttaa taactaatga cgctctacgg acagaatcag 3121 catccgtcgc agaccacccg gcgtctgggt tatgatgact ttttgcatcg gccgattttt 3181 ccgtctggcg aagggcgcgt tcatcctctt tttgttgtag ccgcgaggct cggctttctt 3241 gtgctacctt cgctctttct tctttccatt ttttaatacg ttctgaattt tccacactct 3301 atccgtatat ttactaatta tatatcaaag gaataatctt cagtttgaat cgtcgcctga 3361 tttgactgat attgttcaaa aagcgcagtt gcctgcgcta aatcttcaca cattgtaatt 3421 tttccatgca gcagtacgcc aaacgcatga cagtgttctt taataagccg agggttgtgc 3481 gttagcacaa tcagcccttt ctgttgcagc tgacaagcta gcgccgcctg catacgcaac 3541 tgtgtggcat tatccccggt gtacagcttg ccatcagcaa tataaaggcg gcagggaagc 3601 agtaaattaa tggcaaatgc cagatgcgtt ttcatcgtga cagaatattc actcaccctg 3661 tcggtatagc actgttcaag ctgggtcaat tgataacaga aatgtgaaaa ctcatcgcca 3721 tccaggccat atagacttgc catcattcgc gcattctcct caccggttaa ccctggcaga 3781 ataaaagagt ttgcccccag tgggagcgca tcaccccgta gcccaataaa atccccctca 3841 tcaggagcat ccaggccaca cagcaacctg gttagcgtcg ttttgcctga accaggagcc 3901 gccagaatac cgatatgctc atggtagccc atgacaaaat ctgttttatc aaggaccacc 3961 cgcgggccct tatcagactc aaaatagcgt gtacaaccta ataaaccgaa cacgaatgcg 4021 tctctcctga agctaaagtc agtgattttc agtgtcacaa atcaggtgaa aaatgaggcc 4081 cgcgaggaat aacgttgcgg aaaatgccag agggtaaaaa ggttcaaggt acaaggagtg 4141 atacccctca aacatacctt ctctgactat ctcattagca tgtagtagag ggttccagct 4201 gaatatgctt aataatgaat aaggcaattc attcgccgta taaaagacag ccgaaatcaa 4261 aaacatcggt cttagcatca caggaacagc tttgtagacc agcggaaacc gttcagacag 4321 tgcgtcacaa aagtaaccaa acgataaccc cagaagccat gcgataacca tcccttcaaa 4381 aatcaggaac ggtttttggg cctcccaacg ggagaatata agaaagttaa ttaatgaaat 4441 aataatataa atgataactg cattaacaaa ttcgactgcg gcaagagaaa aaatcacatg 4501 tcttttctta acctgcgaga caaccgctaa cgatgtagag aatgaatggg ttcgcatggt 4561 tgcggtaatg gtataacgaa ataacagata cggtaatatc cctgcaataa caaaactgat 4621 atcgtcagtg gatattggca ccgagcgatt taaatattga aaagaaataa cggtaatgga 4681 tatccatacc agtggtacgg ccagcaccat catatagttt agtaaattac cgttatagcg 4741 tgttttgata tcgcgtgaca tcaataaaat aattaactca cagacggtaa tgagtttcat 4801 aaaataataa gaattatttt tcaaaatatt catatggcga cattagaaag aattagtgcc 4861 gcgggtcaaa aagctatcga atgcggcttt caccttagcg aaatcagtca aagaggcgtt 4921 cgagatatag ataacatcgc cgttgtccac tcgtatggcc tgcgctaaaa acaccgagtt 4981 aggttggctc atatcgacat gatagatatt cagcttacgc atctgctgtt tcgcctgttc 5041 cgcttcgtta tgcttgtaca gaaaaatcgc ttgcggatcg gcaagattgt catttaatcc 5101 tttcgcgagc gccaaagcat ccacgacgct ggaatgacgc tgaaccagag catatttccc 5161 ctgaacacct gctgcgccga gcacattaac atactcggtc acttgacgca gagtgatacg 5221 gtcatccggc tgtaaggcaa tatccaatcc gggatactga taaatatctg acagtcgcgc 5281 agtgaaataa tgctgctggc gcgtcacgtg aacttccatc atatctgtgc tggtattttc 5341 tactgccact gccgttgcca aaagatgact cagacgattc atactctgtt cgagagggta 5401 tcgacccgtt ttcccgctgc cctcgaccgt caccatggct ccggtgcggg cggtaagtgt 5461 cacaatcacc tgaggattca ggacaacgcg cgaaagtcgc tttttgatct catcagccag 5521 ttgcgtcaca tccaatccag aaaccgggat tgtcccggca taaggcacct gaacggtatt 5581 actgtcagtc acaagaatat tttcaaaatc cgcacggtcg ccgctcgcgt tattggataa 5641 atatccagcc ccgcccgagg ataaaatagt gatatgcagc acatcgcctt tagccaaaga 5701 tgtccagtgc cagttatttg cggcaaaaac cggatcgaca atagttttcg gcacagtatc 5761 gggagcgctt agttttaatg tcggcgtgac ttcgaccaga ttataacgag gatcgtcctg 5821 attaataagg ctggatttaa ataccgccct gggaatagtg catcccgaaa gcaggaaaaa 5881 tgtcgttagt aatatgatga tttttttcat aacttatttt ataaatgaaa tagctgaaaa 5941 atgatgccca ttaattaacg aggctgagag gcaatggttt ttacaaacgt tcccaccata 6001 tgttccacgg tgaagcgttc ttgtaaaaat gactgcgtct gttggcaaat accggttctg 6061 ctgcgccata aattgaccaa cttttctgca tagcggcaag cctggtcaag attgaccgtc 6121 tgtgcatcat caagaatgaa acccgaaaca ccctcaataa agcattctgc cgatccacct 6181 gcaggggttg aaatcaccgg caccccgacc atttgtgctt caataagcac attaggtagc 6241 ccttcataac gcgaaaacaa aatgaataca ttcatttttt gcagccaata ccctacgtca 6301 cgcgagacgc caacgaatag tattctctcc agaatcccta actgttcggc gcgtttctgc 6361 gcttcagcgc gtaaatcacc atcgcctacc agcacaaagc gcgtggcggg gtggtgttgt 6421 aaatagcgtg ctgcaaaatc aatccatgca aaagggttct tatcgcctac aaagcggaaa 6481 acgccaccaa tagtcgtgtc cgcatcctgg gttttttgcg taaactgctg ccagatttta 6541 tgtggcacct cagaagaggg ttcagtagat ggcggtaaga cgccgttata tacaacctgg 6601 aagtgcttcg cctccaactt cagccagtcg gcataatggc gagtcacaca atggttgtta 6661 ctcataaaat caacgccagg cacgaccgcc agcgcctggt agagaggctc atattccggc 6721 ttgaacagac gctttctaac caccggcggt aacccacgta atcccagttg aattctgggc 6781 acgccagcaa tcaatgctgc aagcgcaatc atcagacaag cgccatcctg ccaaacggag 6841 agataatcca gcttgcgctc gcataaatgg gggaccagat gcttgatgcc gtagttacac 6901 accggcggta gatgcgatag caataagcgc aactctggag attctattgt cgcatcgtca 6961 aacaagtttc cggtaatctt cgcgatttca agaacctcga cctgttcttc cagcacttct 7021 ttcaggaaaa agtcttgcct gagttccggt gtcagggagc gaataattag ttctaccggt 7081 tcttctactt tcaggccgcc aattttcccc ttttgccgat attttctggc gatttcgata 7141 gccagcctgg aaatctgacg ctctgcacca ccgctaccta gcgagccagt acagagcgca 7201 agacgaccga aagacccgac gggaagctgc ctgggttgac gatttctata gaacaagatg 7261 gcatgcttca ttgcaataat acaggtgttg gtccccacag ggatcgcttt cccttcaagg 7321 cgttcaagca aatcacagat cttatttatt ttgcctaaat aattgttata ttttttctgc 7381 acaccattgc taaccttttt aagaattagc tgagcatctt tggctagccc cgtattatat 7441 aaacgacgtg catactcata acgtgcttca tcattgtttt gtgcaatcag cgtttcgtag 7501 agcgcgtatg cacgctccgt ttcattgaca tcatgaagaa actctgcttt ttttagcatc 7561 gctaatgaag ttaaagcctc agtcggtaat tcactgtcaa ttaacgcaac agcttgcgca 7621 agcttcttct cttgttttaa tgttaaacac gtttttccta gtgcagctaa cttttcttcc 7681 tgcgtaatca ttacgacttc cctgatgtat ttttttgtaa tgcggttatg caggtcgaga 7741 tctgccttgt caccggctcc gttggtccat tcactttctc cagtcgctgc caatactgca 7801 aagcctgcgt gtagtcgcgt aaatgcattg catttaatgc ggcatatttc aaggcatagg 7861 cattttcgct atcaaaaacg agtaattttt tcgcatagtc tagatgttca taagacgtga 7921 tagtgctacc gccatccttc cgtgactcat taaataatct gataatttgc ttatattcac 7981 gcatcagacg agaaacatca ggctcaattc gtttcaggct aatcaataca gacaatgctt 8041 cattcagacg cccttcagtt ttcttctggc gtacatattt aagggctctg gttgcaacat 8101 tgcgacactc tttctcaaac aacttgttca ttgaggcatt ctggaatgat agagtaatgc 8161 tcatgacgtt agcaatcaaa tcaatgagga acggaatgtt gttaatatga cgtatgctgc 8221 gtaacataat cgactgcagg ctggtaatgt tcgagttacg aatcaaggtc atgtgggcca 8281 acgtgcacgc gtctttccag gcaccaagat tcaccagcgt tcttgcacaa tatacggtgc 8341 taacgggatc aaacttcaga agtggccaca ctattttcgc ccctgccagg atattttcat 8401 aatcctcacg ctcatacatt tctcttaatt tatcgcgcca tgccatttta acttcattat 8461 taaagcgaga aatacgtgaa tggggataaa ccataaatgc agagtagcta taggctagcg 8521 aagtactcag tgagacaaaa tcatcaaccg aatgtagcga cagcgcggta ttgttccatg 8581 cctcaaaaac gtcgtggatt ttatctttat acgaggtgcg aagcgcttga tgatagctca 8641 tattcttgat gcagaaagct gtgcggataa cgagaccggt atcatgaatc gtcgacaata 8701 ccgtcagcgc aaattctgac tcatggcgga gtagctgctc gagcgcatgc atgaaaatca 8761 attcatcact gaatttgatt gccaaagata acgccgtttc cataaacgta tcatttaggc 8821 gctgcgattg aatgccggca tggaaagctt cagagaatgc gttgccatca ttgaaatatt 8881 gcgtgctgct caggaaatta acccatccgc tttgagtttc aggattcaat aatagtacac 8941 gtttccaata atgatatgac ttatcaaaca gctgtaaagc atcggctgag ccggcggcaa 9001 cggtaaggac ttcttcatct tcaatttcat tggaaagcat catctctgcc gtcgataagg 9061 cttcccgcca acgcgctaat ccatgtagag acctcagccg acaacgtaat gtactgtcag 9121 tcgtaccgat aattttctca acatcactaa tatcctgata agcctgttca taataaccta 9181 aatggctgaa gattacggac cgaagttgga ttagaacggg ctcttgctgc tgatttctta 9241 atgcggcaaa aagttgttgt gatgcagcaa taatgtcgcc atctgcaagc tgcttagtga 9301 tcgataaggt aatctcacgt atttggtcct gtttctcttg tcgcccctca tcaagatgat 9361 gattagtatt attgatcact cccttaaaaa tagccgcaac gatcgcgtca ccaaacatat 9421 cggtataatg agtaagatcg tcgccatttt tttccagggc tcgtttctgc ccccactttc 9481 ccatcaaatt tgtcgggtta acgcagggaa tatccatcct ggcggcgatg gtgtcgacat 9541 ttttaatcaa ccgactacgg gatagaatga cggttccagc acgagtcacg gcatcaacat 9601 gtgtcataaa cataacgcga tcgcgaccaa gaagctgaac gatttccatc atatcctgtt 9661 cgatagcatg ctcatccatc tgctcgacat tgatattgct taataaggca cgatcgtctt 9721 ccgacattcc ggcaaaacag ggatcgtctt tgagataggc cagcagtttg tgttgatttc 9781 cttgcgtggc caacgaccag tacatgcacg cccgctctgt ttggctaaaa aattcataga 9841 aatgacgagt taaataattt atttgtaagc agaacccata ggccataatc ttcttctgac 9901 ttgaaatctc aatgatatag aaatcagaac gactatgtac gtcggtgttt gaatagttta 9961 cattaggtct aaaaataaat ggtcggacct tttcaggaat gtctatcaag cccaaaataa 10021 accgaatctg ctgtaatgcc tcgctgctcg tatgcgtaaa accatatatt ctcttaaagt 10081 ttgcctgaaa attaaaataa ggctgagctc gttttaccgg actcacaata cggcaactgc 10141 caatggctgt aagcgtaaac atccttgacg atttcattaa attcatccac gtgaaaggaa 10201 agtgagtagt tataccgagg aatacaaagt agaatgttta tcgatatacc attttagagt 10261 ctgcttaagt ccttctttga tatcaaattc aggctcatat gaaagaaatg tttttatttt 10321 ggtaatatct gcctggctat gcttaacgtc accgtcacga aaatctttat aaattggttc 10381 agctctactt tgttcgttcc gccataaatt aagcccatcg cgaattagat aataaagctc 10441 atttaacgaa gttctatctc caactgccac attatagacc ttatttttag aggctaaatc 10501 attagttgtt gctgataata gattggcctg aatcacattc tctatatagc aaaaatccct 10561 gcttgttgag ccatcgccat tgatataaat tggttcatct ttaagaagcg atagtatcca 10621 gcgaggaata actgccgagt acgctccgtt aggattttgg cggcgaccaa agacattaaa 10681 gtagcgtagg ccaatagcgt taaattcata gctacgtgca aacacatcag cgtacaattc 10741 attgacgtat tttgttaccg catacgggct gagtggtcga ccgatccgtt cctcaatttt 10801 aggtaaatcg ggatggtctc cataggtgct actgcttgcg gcgtaggtga aactagagac 10861 atgagcatct ctcgccgccg tcaacatatt taaaaaacca tcaatattgg cgctattagt 10921 cgcgatggga tcctttaggg aacgtggcac gcttcctagc gcggcttggt ggagaacata 10981 gtcaacgttc ttacacgctt tctgacagtc agtaaatttc ctgatgtcac cctgaataaa 11041 aataaatcgc gaccattgct cctcactgac ggacgtgcga acgtcgtcta gattatgctg 11101 ataaccggtg gaaaagttat ccagtccaat gacagtctgg ttgagaaaga gtaattcttc 11161 taataagccg gagccaataa agcctgctac gccagtgatc agccagcgct ttggtgccag 11221 aaccagtttg gtccgtagtt cttcgtaagc cgtcatgatt acaatctcac atctgactgc 11281 tcagccggaa gaacatactt caaatcataa agtacatgtt tatcttttcc gaagccgcga 11341 atatcctcac ttcccatctg tttaaattgc tgatgtccta ctgcaacaat gatcgcatcg 11401 tagtggcttg atttgacttc cgataccggg ataatgccat actctcgtct tacctcttcg 11461 gcatccaccc atggatcaaa aatatccact ttacaactat atttaccgag ttcctttacc 11521 acatcaataa tgcgtgtatt tctgatgtcc ggacagtttt ctttaaaggt aaagccgaga 11581 atcagcacgc tggaaccctc aacgttaatt ccttttttga tcattgcttt gatcaactgc 11641 tcggagacat agttgcccat gttgtcgttc aggcggcgtc ctgcaagtat gatttctgga 11701 taatagccaa tgccctgaga tttatgtgtc agataatagg gatctacgcc aatacagtga 11761 ccaccgacca gtcccggacg gaatggcagg aaattccatt tgctgccagc ggcacgtagc 11821 acggcttcag tatcgatatt taaacgatta aaaataatcg ccagctcatt gaccaaggca 11881 atattcagat cgcgttgcgt attttcaatc accttcgctg cctcagcaac tttgatgctc 11941 tctgctttat atgtacctgc gctgatgatc tgctgatata cttcatcgat aagttcggcg 12001 atctgtgcgg ttgaaccgga ggtgattttc ttgatgttgg ttaaacggtg ctttttatca 12061 ccgggattga tcctttccgg gctataaccg acatagaaat cctggttgaa agtcattccg 12121 gacatacgag caaggatcgg cacgcattct tcttcggtac atcccggata taccgtagat 12181 tcatatacca caatatctcc ccgattcagc actgtaccaa cggtttcact cgccttgatt 12241 agtggggtga ggtctggttg cttgtaggta tttatcggcg tcgggacggt gatgatgtaa 12301 aaattacatt ctttgatctt ctcaatctcg gaagtaaatt tcagataacg agcctcacgt 12361 aattcttctt cagtggtttc cagattgaca tccaccccat tctttaattc aagaatacgc 12421 tttttattaa cgtcgaagcc aacaacctga cgagatttgc caaattcaac tgccagagga 12481 agcccaacat atcccagccc aataatcgcg atttttacct cgtctatacc gaacactctt 12541 attaatcctt tactaaaatt ttatatttac aaagttaatt ctaggtgttt attcagatac 12601 gctaccgccc ctggccgtag cagccagtat ggttaatgaa aacgtatagc cgtacccctt 12661 tcttacttga atagaacaga agtcgctgag aatatatgta ttaacgccaa tgagtaacga 12721 aaataatttt gtgctgaaac gaaatacttg tccgtgtttt actcaataaa aattaccgca 12781 ttacagtaaa gtaactgaat ccggcaataa cagatagcgc ggctcacgta ctccaaattt 12841 tactgccaat tcttttctcc agcgatacat agtcgatgat gagttcataa atctatcctg 12901 aagctcttcc ataccacttt ccgaaaggaa atatttcatc tttactatat ccttacggtt 12961 aattctgaaa cgataatctc tctgctccgt caagatcttt tcaccacttt ggtgttgact 13021 gacatttctg ataatatcct ggactgatgt tgccgcatcg aaaacagcaa taacattttt 13081 gcactctgtc aaccaaaaac gtgcaagggg cattagtcgc gaacttgaaa tgataacgat 13141 tattttatta atatcactca ttcgcgtgaa aaaattcagg gcatttaaca ggctgtagcg 13201 atttaggttc acaaacaaat aatttctgtc atttgttatc agtgacactt cttcaataat 13261 gccagcagct ccaaccccga aatagatatc attcggaggc cagaaatgat gaaacctcat 13321 gaagtctcct atgctgaaat aacctaattt catctataga aaaggtacag gcaatatcta 13381 attctttgct cctgttaaca attaactaat aataaaatta ttaccctaat tttaatagta 13441 ctaacggcct aaacgggatt tttacacaac agagaattga tgtcaaacct gcacaattca 13501 ttgtttgtac ctatcaaaaa atcttattta gtctagaaaa tcgaatgata aattatgcta 13561 aattgtttgg atagggcgta ttttttaatc ctggcgacca taaaaaatgc taagccattc 13621 ctcaaaataa gaatattcct aatcgtattt gaaataatct gttacaaatt taattgtttg 13681 cacctttggg gttaaacctt aactgtacag aatcacaggc tgtattttaa ttactctttg 13741 ccctgtttcc atttcaaatt aaagatatgg ataatgacta ttgttagtta acttttccgt 13801 tgacgatgtc tacaaaatat tttctcgcta gatgtttgca ttagagtcac ccattaataa 13861 tgaccggaaa accgtcagaa cgtcatactg gttttataat ttccggtgaa atgatggtgc 13921 gtgactgctt cggaaatgaa taccttattc atgccggcga agcatttgag gtttctgaga 13981 atcatgatgc ctgggtagtg ggtgatactc cgtgtgttgc gctggatttc acgcatttcc 14041 tccgctgagg atatgaactt gatggtacag ggctggtttg cagaattctt ttttttggat 14101 ttataaattg cactggataa cagtctggcg ggttctcagg atgagcaaaa tgcttttatc 14161 cggagcccga ttatgcccca cactgatact cctgaacagg ctgctgtcat cgcatggaag 14221 ggcgaacgtc tggttgtctg tgcttttgcc gggagtggca aaaccaccac acttcgtcgt 14281 tatgctgagg aaaatccaac ggaacgaatg ctctatattg cttataaccg tgccattcgg 14341 gatgaggcgg agcagaaatt ccccttcaac gttacctgca aaacatcgca tcaactggcc 14401 tggccgacgg tcgggaaaca ttacagtcat cgtctgatta attcactacg actgacctat 14461 gtcgcccggg cgctaaactc ccgcaactgg ttgctggcca gactgacgct tgatgttctg 14521 aatcgcttta tatgcagcgc ggccaccgat attacgcctg aacacatgcc tgatcctgac 14581 gactgtaagg ggctacaacc aggtcaaatc ctgttttcag caaagaaaat ctgggcaatg 14641 atgtcggccc gtcaggggga ttttccggtc acccatgata cttatctaaa gctttaccag 14701 ttgagcaaac cgaatctttc ttcccgctat accacgttat tgtttgatga agctcaggat 14761 gccaatcctg tcatcagcgc cattgtgctc aaccagacct gccgggtagt tctggttgga 14821 gatactcatc agcaaatcta ccgctttcgt ggggcggata atgccatgca ggctccgcaa 14881 ctggagaact cagaccgtct ttggctaacc cacagctttc gcttcggtcc ggaggtagcc 14941 ggggtggcca acaggctgct ggccctgaag ggcgaaacgc atcagataac tggaaagggg 15001 ggcgcaggcc gtgttctgct cacaatgccg cggaattttg gccatcatgc tgttcttcac 15061 cgatctgtct gtggtgtcat ccggacggca ctgcactggt cgctggctgg caggaaagta 15121 ttctgggttg gtggtatgga aagctacaga attgaggatt tactggatct gtactggttc 15181 tcaattgata tgtcggagcg tatgcgacac gacaggctga cccgtgaata ccgggactat 15241 gatgaatatc tgcagatagc cgaagatacc ggtgatgtgg agatgaagca ggggatattt 15301 attcttgaac agttttttcc gttaccggac agactgaata cgttacgtga gcaacgcgtc 15361 atcagtgaat ctgaagctga tgtgacggta tgtacagcac acaggagtaa ggggctcgaa 15421 tgggacaggg tgaagttaca tgatgacttt ctcgatattc tggatcctga catgccggaa 15481 agtcagcggc aggatgaaat taacctcatg tatgtggcag ccacccgggc gcgtaaagtg 15541 cttataaccg atccgatatt gcacgagctt ctgatccagc cccgggctga agatatagcc 15601 ggaacttctg cggataaatc gggtgagtca gaagtgagta cagaaaacga taaaaaaggg 15661 actgaatatg ttccggaaag ttaagtcatg gatggagaag aaaaacttca gacagataga 15721 agaaaataaa tcgggaaatg cgaagaagag acttattccc tgtacggatg gatattttaa 15781 ccctgcggcc atttcagatt tgttacagca tgaacgacgg cagcaatggt taaggatttt 15841 gtgggagaac agcgcgctac ctaaagagcg ttttgaacgt tattttttac tccctttaca 15901 cggcgttgtg ggtttatgtc agagactccc ggcttcggct cagggaaaat ttgcctatac 15961 agacggcatg gtggattacg tcatacagac gacggtcttt gccgtacgtt tatcaaaagg 16021 atatatgctg ccccgaggtg catctgcaga ggaacaatcc gcgcagtcag tcagctggag 16081 tgctgtcgtt tattacgctg cattattcca ctcgttgggg cgcttatgga atattgaagg 16141 cgagctccgt agtggtgctg tatggcgccc gggattaagt gttccggaag aaccttatcg 16201 ttttcgtttt aaagcagaac ccgatatagc aggtgctcag gtttatggtg aattgatcgc 16261 tctcagattt ttgccagaac cggttcttca gtggctgggt aaaaaccctg atattctgag 16321 aacattgctg gctttcataa gcggacgtta cagtgatgca atggatatta cggatatcgt 16381 taatgaggcc attgtgcatg ccggagggat acctcttggt tttcccattg cacaggaaga 16441 gcagacttct gaattagcag agatactaaa ccctgccgcg acagtagctc ccgtgttgag 16501 gaaaggttct tctacaactc ctcctgatgt ccctgtcatg gttgatggag ggcaggagac 16561 tactgtcctt ttatcttccc ttgattctga tgctaagcct gaacgtgggg aagggcagcc 16621 tactgctgaa acagatccag atgttcttca ggtcatgtcg attctgggag ggctgacgaa 16681 cactgacaca cagtcgcctg aaaaggaagg cgtgaacaca gagaccgata tggtggcagg 16741 agaatcgttt ccggaagtcg cggttgcact tgagacttca gcagcagaag aggttatcaa 16801 tgacaccgtt accactgaat gcactggatc atcctcgggt ggcatatcat cgctttcctc 16861 aacggagctg ggagatttgt tctggtcctg gctaagggat gggcttcgtg agggggatat 16921 accagtaaat actgctgatg cctgtgttca tctgacttgt ggcttcgtat ttatcagcgt 16981 cccgggtgtt ttttttctgt ttttgaaatc acattcgcgt tcctgttctt ctggtctgaa 17041 agaaagcggg aggaaggagc aggtgcaggc ggcatttgag aagatgcgaa agcatcgggt 17101 cagtgattcc cggcgattct ggcagtgctg tctttatgaa gagccagggg gcagggggag 17161 atacaaaaag ttaacagggt atctgataaa aatgtcagag atttatgcta atggtaactt 17221 tcccgacgac agtttatttc taaaggtcat caattgaaat aaaatgtaac aaaataaata 17281 taagaaaagt cttaaaaaac catcagttcc tgtaacaaat tgaaatattt ttccgttgtc 17341 atgtgcatga aattacggga atttaaatcc acacaagctg tgtgtgtatt aataataaaa 17401 gctcaatagc ggtgataaaa atggaaacaa atattacctg gcaacaattg atagatgaat 17461 atttcttcgc aaaacctctg cgctcagcat ctgaatggag ttacaccaaa gtcttcaaat 17521 catttgtaca ttatatgggg ccgttaagct gccctaatga tgtgacatat cacaaagtgc 17581 ttgcctggcg ccgttttctt ttaaatagag aaaaagctgt ccggacgtac ctggaataac 17641 aaggtggcgc atatgcgggc catctttaac tacggaatac agcgagggtt actgcactat 17701 gacgaaaatc cgtttaacaa ttcggtagtt aaaccggaca agaagagaaa gaaaacgctc 17761 actcaggcac agattgagta tgcctatcag atcatggagc agtatgaaaa tcaggagaat 17821 acagggctgg gactgaaata ttcccgctgc gccttatttc ctgcatggtt ctggctcact 17881 gtcctggata cgctctatta cacagggata cgtcagaacc agttattaca tattcggctg 17941 aatgatgttg atttgagaga agggcagatt cggctgatta cggaggggtg taaaaatcac 18001 aaagaacact atgtgccggt gatcagtttt ctgcgtccac ggctgacctg tttaatggag 18061 aaagcgcaga gcgaaggatt gaaaggtaat gaccgcctgt tcaatattgc actttttacc 18121 ggcaaagatc ccgccattgg cgatgacatg gattctcctc aggtaagagc attcttccgt 18181 cgtctgtcca aggagtgtca gtttgcgatc agtcctcatc gtttcagaca cacgctggcc 18241 acggagatga tgaaaatgcc ggaacagaat ctgcatatgg cgcaaagtgt gctgggtcat 18301 tcaaacatga aatccacgct ggagtatgtg gagaatgata ttgcagtgat ggggagggct 18361 ctggaagcgc agtttatgca gattaaggca gcacatgccc gaagcattta cagtgggttg 18421 acaaagaata gataa //