LOCUS NC_010723:6 26592 bp DNA linear BCT 25-AUG-2011 DEFINITION Clostridium botulinum E3 str. Alaska E43, complete genome. ACCESSION NC_010723 SOURCE Clostridium botulinum E3 str. Alaska E43, complete genome. COMMENT locus start: 420025; locus end: 446616 FEATURES Location/Qualifiers source 1..26592 /organism="Clostridium botulinum E3 str. Alaska E43, complete genome." gene 0..1481 /gene="" /locus_tag="" /db_xref="420025..421506" CDS 0..1481 /gene="" /locus_tag="" /product="putative extracellular solute-binding protein" /translation="LKKYLLPISLIFMVGAFLLGFIQIDNVSSDKKGEEVINYGVEDI PENLKTVTNLSKRNEDIICAISKGLVSKDIDNNIVPSLAKEIIKSEDGIEYEFKINDN IYWSDGSKITSDDVIVFFRELLKEDDEENIHALLDVYGAREFKDGKTTFEKGVAIKSK DNSVIIRLNAKNDKFLSELTKPQYRLRKYLIMWENIKKNYNDLVYSGDYKITSFVDDK ITLQSNNNDENRRVINLINDSNVELSMASFEIGERDVVINPPQSQLNKLNNDGSLITM PKDTGVYLYINDKNNISLQGRREIYKYISESMEEYSSSNEKSFELAEGSYFRENKEDL TKLQTRKVISNKEEAWSPPKVLTILCRDDSINRELCRVIAKWFDENTDISIKYSLLKD DEFNDEELQKRYDMILINNEANIFDKDKFYKKFVNYMSDDEKEILLSSNCNDDVYINL ENKIFEEYKIVPLIFYNENIAYSKKISNIKMDGNGNIDFSSIQ" gene complement(1554..3191) /gene="" /locus_tag="" /db_xref="421579..423216" CDS complement(1554..3191) /gene="" /locus_tag="" /product="hypothetical protein" /translation="LRYIGPFFRMNSLSQKEISNQLFYLSKESVKTIVLNSKCGLLIP IRVSKKSSSTNDISILNDFSPLICIYKKSSPMFIHNKTSHGFDESTFKKEINPSTNAL MTLCLLELSDYYSNYDKDNRNIISFEKPFKYIAKQQLKFYSKNLRNNEGVFVDKKNTS DGNSKGFNLIDKSDKFNFCDQSFMMVAYYLYSFYNKSDVDSNDYERFSNEILCVLRDY KESLYDLSFEENLNILLCLNIFCKYSESYIAKDLILDLSDFLINRFMIKDYYVNSLEN CCLLAICLMESYKHTNIISFKETSKEINDKLLSLYDNDKNIFIKLTDKKETKYSCLEI NLYLLSLMIYAKEDDKISELKPIISNIYRKLYVNNNLLTSWPEAPTLDEVERYKNLSL KSEDMLDETYFRMPNLPSPESNGLAPVFVKNLSYSRKKDCFTVPKVSFDSNKNMFSFL LFIYFLKDDIEKEMGFNKIKTNITDCRTTTDINEDEIINSAELNDIEIENINISTNLN SSVPDSPKLTTDLNKTTSTLDIKSKKSSKDKSSNKKS" gene 3436..4185 /gene="rph" /locus_tag="rph" /db_xref="423461..424210" CDS 3436..4185 /gene="rph" /locus_tag="rph" /product="ribonuclease PH" /translation="LRIDGRKNEQIRHVKVTRHYTKYAEGSVYIEVGDTKVLCNVSIE DKVPPFMKGTGSGWITAEYNMLPRSTETRKIRDIARLKIDGRTMEIQRLIGRALRSVV DLKALGEKTLWIDCDVIQADGGTRTTAISGAFIALVDAVNKLHKIKPFKIYPIRSFVA AVSVGIVNEEKILDLCYQEDSKAKVDMNIIMTDEGSFVEVQGTGEESPYTRTELNELL DLGEKGIKQMINVQKESLKMDSLWIGTGGNN" gene 4189..4806 /gene="rdgB" /locus_tag="rdgB" /db_xref="424214..424831" CDS 4189..4806 /gene="rdgB" /locus_tag="rdgB" /product="non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family" /translation="MKKLILASNNIKKIKEMKELLKDLNIEIKSLNEENINIDVEEDG STFEENAKKKAKEIYDFLNLRNERNFLVLSDDSGLEVDYLNGAPGIYSARYAGEHGND EKNNEKLLMELSNVPTNKRTAKFVCQIAMFDEEGRYYSITGEANGFVLEKRQGNDGFG YDPLFLYRPLNKTFAELTLEEKNNISHRGVALKKLKKTILNLISE" gene 4818..5297 /gene="" /locus_tag="" /db_xref="424843..425322" CDS 4818..5297 /gene="" /locus_tag="" /product="phosphodiesterase, family" /translation="MLIAVISDTHRMSNYIKMASEYIKEADIVIHLGDNVEDAEEISK EFNGEVYIVSGNCDYKDKYPKEGIIDIEGIRIFFTHGDLYGVKYGLNNIYYKTKELKA DIALFGHTHISMIEKYDDVILMNPGSLSLPRSRGRYIGFIKVEKGENPSVYLKEMGI" gene 5426..5501 /gene="" /locus_tag="" /db_xref="425451..425526" CDS 5426..5501 /gene="" /locus_tag="" /product="tRNA-Pro" /translation="RGVAQMGARVVWDHEVAGSIPVTPT" gene 5520..5593 /gene="" /locus_tag="" /db_xref="425545..425618" CDS 5520..5593 /gene="" /locus_tag="" /product="tRNA-Gly" /translation="AGVAQW*SPSLPS*LREFDSHHPL" gene 5621..5749 /gene="" /locus_tag="" /db_xref="425646..425774" CDS 5621..5749 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MNVKSDLNMRMKKLLDIIRRITYNDKGSSVKEFKSGFEGLKK" gene 5829..5907 /gene="" /locus_tag="" /db_xref="425854..425932" CDS 5829..5907 /gene="" /locus_tag="" /product="tRNA-Arg" /translation="CVFSSAG*SNALLRRGPGVRIP*DAP" gene 5912..5989 /gene="" /locus_tag="" /db_xref="425937..426014" CDS 5912..5989 /gene="" /locus_tag="" /product="tRNA-Pro" /translation="SGCGADGSARGLGP*GRRFDPCHPD" gene 6011..6084 /gene="" /locus_tag="" /db_xref="426036..426109" CDS 6011..6084 /gene="" /locus_tag="" /product="tRNA-Gly" /translation="AGVAQW*SPSLPS*LREFDSHHPL" gene 6098..6176 /gene="" /locus_tag="" /db_xref="426123..426201" CDS 6098..6176 /gene="" /locus_tag="" /product="tRNA-Arg" /translation="CVFSSAG*SNALLRRGPGVRIP*DAP" gene 6180..6257 /gene="" /locus_tag="" /db_xref="426205..426282" CDS 6180..6257 /gene="" /locus_tag="" /product="tRNA-His" /translation="GECSSVGRAPVCGTGCRGFESHRSP" gene 6259..6335 /gene="" /locus_tag="" /db_xref="426284..426360" CDS 6259..6335 /gene="" /locus_tag="" /product="tRNA-Gln" /translation="LGCRQAVRQWTLTPLCVGSNPAIPA" gene 6340..6417 /gene="" /locus_tag="" /db_xref="426365..426442" CDS 6340..6417 /gene="" /locus_tag="" /product="tRNA-Lys" /translation="WFTSSVGRAHDF*SWCPGFDSRVSH" gene 6424..6510 /gene="" /locus_tag="" /db_xref="426449..426535" CDS 6424..6510 /gene="" /locus_tag="" /product="tRNA-Leu" /translation="CRCGGIGRRTRLRI*RFTAWGFDSLHLH" gene 6514..6590 /gene="" /locus_tag="" /db_xref="426539..426615" CDS 6514..6590 /gene="" /locus_tag="" /product="tRNA-Gly" /translation="SRSDSMVECHLAKVDVAGSSPVFCS" gene 6607..6680 /gene="" /locus_tag="" /db_xref="426632..426705" CDS 6607..6680 /gene="" /locus_tag="" /product="tRNA-Gly" /translation="AGVAQW*SPSLPS*LREFDSHHPL" gene 6692..6769 /gene="" /locus_tag="" /db_xref="426717..426794" CDS 6692..6769 /gene="" /locus_tag="" /product="tRNA-Lys" /translation="CVISSVGRAPDS*SGCPGFDPLITH" gene 6776..6853 /gene="" /locus_tag="" /db_xref="426801..426878" CDS 6776..6853 /gene="" /locus_tag="" /product="tRNA-His" /translation="GECSSVGRAPVCGTGCRGFKSHRSP" gene 6858..6932 /gene="" /locus_tag="" /db_xref="426883..426957" CDS 6858..6932 /gene="" /locus_tag="" /product="tRNA-Gln" /translation="WDVAKR*GNGL*LHYA*VRILPSQ" gene 6953..7030 /gene="" /locus_tag="" /db_xref="426978..427055" CDS 6953..7030 /gene="" /locus_tag="" /product="tRNA-Lys" /translation="WFTSSVGRAHDF*SWCPGFDSRVSH" gene 7035..7121 /gene="" /locus_tag="" /db_xref="427060..427146" CDS 7035..7121 /gene="" /locus_tag="" /product="tRNA-Leu" /translation="CRCGGIGRRTRLRI*RFTAWGFDSLHLH" gene 7125..7201 /gene="" /locus_tag="" /db_xref="427150..427226" CDS 7125..7201 /gene="" /locus_tag="" /product="tRNA-Gly" /translation="SRSDSMVECHLAKVDVAGSSPVFCS" gene 7215..7288 /gene="" /locus_tag="" /db_xref="427240..427313" CDS 7215..7288 /gene="" /locus_tag="" /product="tRNA-Gly" /translation="AGIVYR*YSSLPSWKGGFDSHYPL" gene 7334..7410 /gene="" /locus_tag="" /db_xref="427359..427435" CDS 7334..7410 /gene="" /locus_tag="" /product="tRNA-Arg" /translation="ASIAQLDRALDFESKRRRFESC*MY" gene 7896..8018 /gene="" /locus_tag="" /db_xref="427921..428043" CDS 7896..8018 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKTSNYLSKDFRYVNFNLNKRIYGVKDKISDGEIAINLVN" gene 8356..8802 /gene="" /locus_tag="" /db_xref="428381..428827" CDS 8356..8802 /gene="" /locus_tag="" /product="endothelin-converting enzyme 1" /translation="MLHQTVNAYYNPTKNEIVFLSAILQNPFYDIKNSKVQNLVGIGA VIGHELTHAFDNTGSKFDECGNLNNLCTYKYYEEFNIRSKNVIDYYSHIQINSGEFVN GKLTVGEDVSDFLGASIIDIANSINNANLKELFKNYEIIWREISTK" gene 8803..8937 /gene="" /locus_tag="" /db_xref="428828..428962" CDS 8803..8937 /gene="" /locus_tag="" /product="endothelin-converting protein 1" /translation="MELHLLKNDVHSPKKVRVNTVLSQFEDFYNAYCIKQGGDMYISQ" gene 9352..10858 /gene="rrsK" /locus_tag="rrsK" /db_xref="429377..430883" CDS 9352..10858 /gene="rrsK" /locus_tag="rrsK" /product="16S ribosomal RNA" /translation="ESLILAQDERWRRA*HMQVER*SFFGSGLAADG*VTRGQPAS*R GIAFRKED*YLIRL*FRMKRQ*KE*SAMRWARVALASW*GNGLPRRRCVADLRG*SAT LGLRHGPDSYGRQQWGILHNGGNPDAATPRE**RSSDCKTLSLGTIMTVPKEEATANY VPAAAVIRRWQALSGFTGRKGSVGGYLSGM*NTRA*PECCIPNWISRVQERKVEFLV* R*NA*ILGRTPVAKATFWTVTDTEARKRGERTGLDTLVVHAVNDEY*V*ELSWLLCRR *RIKYSAWGVRSQD*NSKELTGARTSSGACGLIRSNAKNLT*T*HLLNYS**RKSLR* QEDRWCMVVVSSCREMLG*VPQRAQPLLLVATI*LSTLARLPWLTRRKVGMTSNHHAP YV*GYTRATMAGTKRCNTARWS*TIKPVSVRIVG*NSPT*SWSC**SRIRMSR*IRSR ALYTPPVTP*ELAIPKVRELTRKGGSDLR*GQRLG*SRNKVAVGEPAAGSPP" gene 10982..11058 /gene="" /locus_tag="" /db_xref="431007..431083" CDS 10982..11058 /gene="" /locus_tag="" /product="tRNA-Ile" /translation="GLIAQLVRAHA**A*GRWFESI*AH" gene 11237..14146 /gene="rrlK" /locus_tag="rrlK" /db_xref="431262..434171" CDS 11237..14146 /gene="rrlK" /locus_tag="rrlK" /product="23S ribosomal RNA" /translation="GQATKGAW*MPWHQEPMKDAISCDKLRVDAHSQRSEDFRMRKLT WETPCIVK*IHSFMKVNPGN*NI*VPGGRERKIDFLSSGERKGKSPNQRFIFGVADRT LTRNYS*PNTTGKLDRRG**SCR*KL**SSSDPEYHETRETLWEAGRTTSQG*ILPDD R**SSTVRER*KEPREGSEIEPETMCLQPIKAPYVCDDVLFVERANELRYVARLST*G TEPKGNRVLIGRLVACCRPETG*PIHGQVEARVKPRGGPNHVAVEKAWDELWIAEKFQ SNSDIAGSPRNSFRASVGKCEYWG*STEWARGHSAYRTLSNSEYQILSVRQSDCER*V P*SKGKQPRSSAKVPKCKLSGKGCGISKTTRMLA*KQPLIKRVRNSSLVKRSCAENVR GSNLPPKLRVHTIV*AVEERRNRAEVVP*GAVD*LRVRMLALVARCG*ESHRPNT*GF LRKVRPLRVSRDLS*GRKA*AMDNRLIFRYHYYRYYRWCDGEG*DVLAIGC*SKRLGS *NRQIRSNNSEA*WGRF*GTEVSDSMLPRKASRKRNSARTANRHR*VRRES*GRRKNC S*GTRQIDPVTSGEGVPARAGRRE*AQATV*QKHRSLLKRKLMYRG*RLPGAGRLRGT LSVSEGVNLSPSKRRP*L*RS*GSEIPCQVSSDPHEWRNDLCTVSTANPAKL*CE*RC SLPAIGRKDPVELYCSLALNFGIVCTG*VGDWEIRASALMESSLGYHPDSTGILTGCH ESGDRTLLGGQFDWGGRLLKSNGGAQRFPQNGRKSFVECKGIREPDCETYKSSRDESR A**SGGTSWEGHRSTDKSYLGDNRLISPKSSHRRGGLAPRCRLVASWG*SRSQGLGCS PIKAARELGSERRETVRSLSVAGAGNLRRAVLSTRGPGWTDLWCTSCFARSIAG*LSR DGINAESI*A*SLLQDEISHSVS**DPLKTTRLIGQRCKCGNIFS*LILIGRGLD" gene 14206..14282 /gene="" /locus_tag="" /db_xref="434231..434307" CDS 14206..14282 /gene="" /locus_tag="" /product="tRNA-Asn" /translation="FRDSSMVEHSAVNR*AGGSSPLRGA" gene 14467..15414 /gene="" /locus_tag="" /db_xref="434492..435439" CDS 14467..15414 /gene="" /locus_tag="" /product="polysaccharide deacetylase family protein" /translation="MSNNVNYRRRRDGKNKKKKIILFSSIVLVVIVSGMLSAKYIHSK SINADASERTNNNEIINENKVDAAPKEELKLDNSGYLTAEEDPNADSAAFVEKYLYEQ SLGKMPEGADGHKVAYLTFDDGPSESVTPEVLKVLKEKDVKATFFTLGKSINESDRTK ELLKEIVKDGHAVASHTYSHDYKYLYPHRTVSIENFMGDIEKNNETFRQVLGKDFVTK TIRFPGGLMSWNGQDAIKEKLQEGGYSYIEWNALSKDAEGKTKVASELLEEVKKSVAG REKAVILMHDASGKDETAKALPGVIDYLREQGYEFKSIK" gene 15516..16205 /gene="" /locus_tag="" /db_xref="435541..436230" CDS 15516..16205 /gene="" /locus_tag="" /product="alkaline phosphatase synthesis transcriptional regulatory proteinphoP" /translation="MRRILLVEDEESIRGFIKINLKRNDFEVIEAECGEDGLKAAEKF SIDLAVLDVMLPGIDGFKVCDELRKRYPKMGIIMLTARTQDMDKIMGLEYGADDYIIK PFNPLELILRIKAILRRTGDESQVKENIDKLIREPFIIDLYSQKLFKDNIEIDVTPKE YLLMKLFLKNPNKAFSRDELLNLIWGYDYFGDPKLIDVNIRRLRSKIEDTPSEPEFIE TIWGKGYRWKG" gene 16210..17607 /gene="" /locus_tag="" /db_xref="436235..437632" CDS 16210..17607 /gene="" /locus_tag="" /product="alkaline phosphatase synthesis sensor protein PhoR" /translation="MKSIKNTLIRSFIFLILFIVICMNILLGTLVKKYYYDNAETLLR NQIEIATNFYNKYLYRSSLIENIYDNVDSFWNKNNAEVQILDEKGNLLMDSIGVYDND LHEKPDVKKAINGESGSYVGNVSYSNYKVMSVSEPLLNDNEVIGIIRYVISLEEINNE LKNIVFCFMLISILVLFLGIIISLILSNKIINPIKKLTDISQKMANGNLNVRNNISGE GEVAQLANTLDYMAEEIIKREKLKDDFISSVSHELRTPLTSIKGWVITLQDDNTDKET FKLGFNILEKETDRLSNMVEELLDFSRLINGKMQLKREKVNVMELIEYIESYMIPRAL KECINFNVLSNLDNKIYYLDIDRMKQVLINLIDNSFKFVNKNGNVNVIFNEGEDDLKI VVEDNGCGISKSDLPRVKEKFYKGANSKSQNGIGLSICEEIVNLHNGYLDIVSEEGKM TRITILIPNIRETDV" gene 17604..19061 /gene="" /locus_tag="" /db_xref="437629..439086" CDS 17604..19061 /gene="" /locus_tag="" /product="putative lipoprotein" /translation="MKKFINIFLVVLISFFITGCNEVSQNKIYKIKAPQNNSLSIKGV WRVDNYKVLDDDIYSLNNRKFLVGEDIEICNEYIALKNIEYSNISYKLKLVKDDYVIS YEEKYNIGNLNLNKENYEVISVFNDNNIIFEFIKDTSESGLIFYNGALYNVSLVGQIN EDIENNIKKEEHKSDSRLVNDYNSPVGVYLGIKSKNKEDNTEEYKTLYVSFKDGKLQP IREKEGLIVPRMNGIWYINKEFVEKNDYYYEYFDAKPINNKEFANSSNKKIENIDKNK YISINFVGNDYIATEVYEGKNFDGEYGKYEVLPIDNITSNIPIVISDIFPADDSKSFK QTYDKVINSFSDEDKQKYSPYMNYSNFSLKRVNGKWTVVGKISPAYGIDGSGYDYTLN LKQNKKLLNYDSLLIPWKTLKRELPGIKDAFTSPNKRIALILTEKALLIDEIENYKIN NVPLDIIDMNENDEIIMAEWCIGDYVDNWEKPFLN" gene 19349..20731 /gene="" /locus_tag="" /db_xref="439374..440756" CDS 19349..20731 /gene="" /locus_tag="" /product="TldD protein" /translation="MLEKSIVSQVLARCLITGGDFAEIFEDDSVNNSISLIDGKVEDA IGGRNYGIGIRIFKGLKSVYAYTNNNSLDSLLETAYRAALALGNANEEEKNIILNEKK IQTIHPIMFYPKDVNYNKKIDILKLAYNSAKNYNSEISQVITSYGDKEQNILIANSDG LYIEDKRIRTRLGINAIASKGSENQTGFEGPGRYMGIEMFESIDPEYHGMEAARIAHT MLHAKNCPAGNMAVAIDNGFGGVIFHEACGHALEASSVAKGNSVFANKLGEQIASTKV TAIDDGTIANAWGSLNIDDEGNKTQKNILIENGILKGYMIDKLNGRRMNMKPTGSSRR QSYKYQPTSRMTNTYIANGMDNPEDIIKSISDGLYAKKLGGGSVNPITGEFNFAVQEG YLVKNGVIKEPVRGASLIGKGSEVLMDIDMVGNNLELAQGMCGSSSGSIPTNVGQPMI RVKKMTVGGR" gene 20735..22078 /gene="" /locus_tag="" /db_xref="440760..442103" CDS 20735..22078 /gene="" /locus_tag="" /product="TldD/PmbA family protein" /translation="MEFNLFKEKLMSEAKKAGFDECEIYYSDAESLSINIYDGDVEKY KLNNSFGLSFRGKINEKMGYSYTEILDEDSISTLIENAKGAALVIENDDTQFIYEGDN EYKEINCYKNELDNIKPDKLIKLALEMERECKKQCDKVVNFGGCGIGYGKSSYGILNS KGLDLSTSRNHLTAYVVPIIEDNNEKYDGMGYVIAKGEADINPEKLAKDGLEEALSRI GGRSIESGKYKVVINNEAMVSLLGTFSGIFNAEQAQKGLSLLRGKEGEIIASDKVTLI DDPHLEDGLGTTAFDDEGVATYKKEVITNGKLNTLLYNLKTAHKANVKSTGNGFKSSY ASIVGISPTNFYIKPGKKDFEEICKEVNNGVIITEFAGLHSGANSVTGDFSLASKGFM IENGKKTFPIEQITVAGNFFTLIKDVEEIGSDLKFPMSSVGSPCVVIKELSIAGK" gene complement(22432..24282) /gene="" /locus_tag="" /db_xref="442457..444307" CDS complement(22432..24282) /gene="" /locus_tag="" /product="sulfatase" /translation="MHSNKNKITDFLNKSRLNQLILFLFPLISIFLKCIFFQGFITGS NPYSFNFNTGYDYARPFFNYYLAFILIFISFSLLFKGKARIIYLFTINILLTAIIVLD VCYFRGFLTVPSILIATQTANLDNLSGAVYSMFSPLDVIFIIDFFLFGIYVYFTRKYV SKINKRAIKTFLITFIMPILFIGYVPFNIHILNNKDVKDSYLYDNYDPTNTARYFSPI GYHIFDLYTVYRDSKPYEFTVEDENNLNKLFNMKNENLPNNDYFGISKGKNLIYIQVE SLESFVINKSINGKEITPVLNNLTSKGFYFPNVFEQVNEGTSSDSDLMVNTSMFPLRR GSTFFRYPNNTYNSLPDILEKNSYSSIAIHPDKGSFWNYSAGLKGIGFDKFNDYYSFN ADETIGMGISDASYFKQVVPMLKEQSNPFYALTVTLTSHGPFDIPKEYRELGLDPELD ASELGGYFESLHYTDAQIGNFLKLLHSEGLLENSVIAIMGDHTGVHKYYNNGIEKLSN KEDWYLDTGNPVVPLLIYDTSINTGKTFDLYGGQIDVMPTLLYMLGIDKEKYQNTALG RNLLNTNKSFAILTDGTIKDQNTLSDEDKETYKNILDLSDKMIRANYFKK" gene 24466..25044 /gene="" /locus_tag="" /db_xref="444491..445069" CDS 24466..25044 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKEIDCRGLSFPKTIRMVKKYFNSIGEGEAIVIIEKQADNSNIA NLAMNLGYHVDVEENDENIHIFIEKRGCLEAIDETVFSVLITSDKFGSGDSKLGKILL NDYLNALSDAIKLPKNIIFLNEGVKVFQDVSDNINWLENIKLLSQEGVSILVHDKSLE YYKLDISNNFSEVIDMSDLVDIINESNNLIKL" gene 25075..26031 /gene="gidA" /locus_tag="gidA" /db_xref="445100..446056" CDS 25075..26031 /gene="gidA" /locus_tag="gidA" /product="tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA" /translation="MLEYDLVVIGGGIAGMTAALGAAREGINNILIVEREHSLGGILN QCIHNDFGEKFVGEKVTGPEYIFFIEEKLKKLNIDIKLNTNVIDIIDDNKITYVNSIE GSKEINTKAIILATGSREVYTGSVMVPTHGLTGIFTLGSAHRLINLEGYLPGKKTVII AKNKWGFLVARRILIEGGSVEAIIIEEEIKELIDEEIENLINGFSLDIIENSRVVEIY GDSRINKIKILNLKEDVISKIECDSLILSVGFRPENKLAQSLKLDINKNTFVPEINDF KTSKESVFACGNLIYGKLALIMEETDGLNCGIRAAEYIKNIN" gene complement(26028..26591) /gene="" /locus_tag="" /db_xref="446053..446616" CDS complement(26028..26591) /gene="" /locus_tag="" /product="putative esterase" /translation="MIKHVDIIFLGDSLTFGYGVPKKDSWVYKIQNNINVTSLNNGCN GDTSIGMLNRYYEDVIRYTPTKIFIMCGSNDLLLGRTVKSIIENIELMIKDSLEINSN VVIGIPPSIIGAMANKLFSSSPFYTYAEENLIKLREAIINLAVNYSLSYIDFYSITLN NSDIYLDGIHLNSLGNEIMYKNAVSYF" ORIGIN 1 ttgaaaaaat acttgttacc tatatcctta atttttatgg taggtgcatt tttattagga 61 tttattcaga ttgataatgt ttcatcagat aaaaagggtg aagaggttat taattatgga 121 gtagaagata ttccagagaa tttaaagact gttactaatt tatctaagcg aaatgaagat 181 ataatttgtg cgattagtaa aggcttagtt tcaaaggata tagataataa tatagtacct 241 tccttagcta aagaaataat taagagtgaa gatggaatcg aatatgaatt taagataaat 301 gataatatat attggagtga tggaagcaaa ataacttcag atgatgtaat tgtatttttt 361 agagaattac taaaagaaga tgatgaagaa aatatacatg cattattaga tgtttatgga 421 gccagagaat ttaaagatgg gaaaactact tttgaaaagg gtgttgcaat aaaatctaaa 481 gacaatagtg tgataataag actaaatgct aaaaatgata agtttttaag tgaattaact 541 aaacctcaat atagactaag aaaatatttg attatgtggg aaaacattaa aaagaattat 601 aatgatttgg tttatagcgg ggattacaaa ataacatcat ttgtagatga taaaattaca 661 ttacaatcaa ataataatga tgaaaataga agagttataa atttaataaa tgatagtaat 721 gtagaattat ctatggcatc atttgaaatt ggagaaagag atgtagttat aaatccacca 781 caaagccaat taaataaatt aaataatgat ggaagtttaa taacaatgcc taaagataca 841 ggtgtgtatt tatacataaa tgataaaaat aatatttctt tacaaggtag aagagaaata 901 tataagtata tatcagaatc tatggaagaa tactcttctt caaatgaaaa atcatttgag 961 ttggctgaag gtagttattt tagagagaat aaagaagact taactaaatt acaaacaaga 1021 aaagtaataa gtaataaaga agaggcatgg tctcctccaa aagtacttac tatattatgt 1081 agagatgata gtattaacag agagctatgt agggttatag caaagtggtt tgatgaaaac 1141 acagatatat ctataaagta tagtttatta aaagatgatg aatttaatga tgaggaatta 1201 caaaaaagat atgatatgat attaattaat aatgaagcaa atatttttga taaagataag 1261 ttttataaaa aatttgttaa ttacatgagt gatgatgaaa aagaaatttt attatctagt 1321 aattgtaatg atgatgtata tataaattta gaaaataaga tttttgaaga atataaaata 1381 gtaccattaa tattttataa tgaaaatata gcgtattcta aaaaaatatc aaatattaaa 1441 atggatggta atggaaatat agatttttca tctattcaat aatttattgt agattaaggc 1501 tacatcattg ataataaatc catgatatag ccttatatat tttacaatac attattaact 1561 ttttttgtta ctagatttgt cttttgaaga cttttttgat tttatatcta aagtagatgt 1621 tgttttattt agatcagttg ttaattttgg agaatcagga actgatgaat tcaagtttgt 1681 actaatattg atattttcaa tttcaatatc atttaattct gctgaattaa tgatttcatc 1741 ttcattaata tctgttgtag ttctacaatc agttatattt gttttaattt tattaaatcc 1801 catttctttt tcaatatcgt ctttaagaaa atatataaac aatagaaaag aaaacatatt 1861 tttgtttgaa tcaaaagata ctttaggtac tgtaaaacaa tctttttttc tggaatagct 1921 taagttttta acaaatacag gagctaagcc attactttct ggactaggta agttaggcat 1981 tctgaaataa gtttcatcta gcatatcttc ggattttaag cttaaatttt tatatctttc 2041 aacttcatct aaagttggag cttcaggcca acttgttaac aaattgttat tgacgtaaag 2101 ttttctatat atgttagata taataggttt taattcggag attttatcat cttcttttgc 2161 ataaatcatt aaagatagta gataaagatt aatttctaaa caagagtact tagtttcttt 2221 tttatctgta agcttaataa aaatattttt atcattatca tatagactta ataatttatc 2281 attaatttct ttactagttt ctttaaaaga aattatatta gtatgtttgt aagattccat 2341 taagcagata gctaataagc aacaattttc tagtgagttt acatagtaat cttttatcat 2401 aaatctattt attaaaaaat cacttaagtc cagtattaag tctttagcta tataactttc 2461 tgaatattta caaaaaatat tcaaacataa taaaatattt aagttttctt caaatgataa 2521 gtcataaaga gattctttat aatctcttaa tacacataaa atttcattag aaaatctttc 2581 ataatcatta ctatcaacat cagatttatt atagaaagaa tatagataat aagctaccat 2641 cataaaagat tgatcacaaa aattaaactt atcacttttg tctattagat taaaaccttt 2701 agaattacca tcagatgtat tttttttatc aacaaaaacc ccctcattat ttctaaggtt 2761 ttttgaatag aattttagct gttgttttgc tatatattta aatggctttt cgaaagaaat 2821 aatatttcta ttatctttat cataattaga gtaatagtca cttaactcta atagacataa 2881 agtcattaaa gcgtttgtcg aagggtttat ttctttctta aaagtagatt catcaaaccc 2941 atgtgaagtt ttattgtgta taaacatagg ggatgatttc ttatatatac atattagtgg 3001 agaaaagtca tttaatatgc taatatcatt tgtagaagaa gatttttttg aaactcgaat 3061 aggaattaga agaccacatt ttgaattaag aacaatagtt tttactgatt cctttgataa 3121 ataaaaaagt tgattactaa tttccttttg agaaagacta ttcattctaa aaaatggccc 3181 tatatatctc aattatattc acctctctaa aatttctcat actattaatt aatatgagtc 3241 aaattcaaaa atagtgcata aaatctaaat aaaaggtgaa attttttaat aaagatatta 3301 aaaaggtctt taaagtaatc tattatttat atattaatat ttaataaatt aagtaaaaac 3361 aataattgat ttttaaaata tatataatat aaaaaataat aaattttgaa atatatgtgt 3421 ttggagtgtg atttcgttga gaattgatgg aagaaaaaat gagcaaataa gacatgttaa 3481 agtgacaaga cattatacaa agtatgcaga aggttcagta tatatagaag tgggagacac 3541 aaaagtttta tgtaatgttt ctattgaaga taaagttcca ccatttatga aaggaacagg 3601 atcaggatgg attacagcag aatataatat gcttccaaga tcaacagaaa caagaaagat 3661 aagagatatt gcaagattaa aaatagatgg cagaacaatg gagatacaaa gacttatagg 3721 aagagctttg agatctgttg tagatttaaa ggctttaggt gaaaagacat tatggattga 3781 ttgtgatgtt attcaagctg atggtggcac aagaactaca gctatttcag gagcatttat 3841 agcattagtt gacgctgtta ataaattgca caaaataaag ccttttaaaa tatatcctat 3901 cagaagtttt gttgcagcag tgagtgttgg tatagttaat gaagaaaaaa tattagattt 3961 gtgttatcaa gaagattcaa aagcaaaagt agatatgaat ataattatga ctgatgaagg 4021 tagttttgtt gaagttcaag gtactggaga agagagtcca tatactagaa ctgagttaaa 4081 tgaattatta gatttaggag aaaagggaat aaaacaaatg attaatgttc aaaaagaatc 4141 attaaaaatg gattctcttt ggattggtac aggaggtaat aattagaata tgaaaaaact 4201 tattttagct agtaataata taaaaaaaat aaaagaaatg aaagaattat taaaagattt 4261 aaatattgaa ataaaatctt taaatgaaga aaatataaat atagatgtag aagaagatgg 4321 tagtacattt gaagaaaatg caaagaaaaa ggctaaagag atatatgatt ttttaaattt 4381 aagaaatgaa agaaattttt tagttcttag tgatgattca ggattagagg ttgattattt 4441 aaatggtgca ccaggaatat actcagctag atatgcagga gagcatggaa atgatgaaaa 4501 aaataatgaa aaattattaa tggaattatc aaatgtccct actaataaaa gaactgctaa 4561 atttgtgtgt caaatagcta tgtttgatga agagggaaga tattattcaa taactggaga 4621 ggcaaatggc tttgtgttag aaaagcgaca aggaaatgat ggatttggat atgacccttt 4681 gtttttatat agacctttaa ataagacttt tgcagagcta actttagaag aaaagaataa 4741 tataagtcat aggggagtag ctttgaaaaa attaaagaaa acaatattaa acctgataag 4801 tgaataggag aacaaattat gttaattgca gtaataagcg atactcatag aatgagcaat 4861 tatataaaaa tggctagtga atatataaaa gaagctgata ttgttataca tttaggagat 4921 aatgttgaag atgcagaaga aatatctaaa gaatttaatg gtgaagtcta tatagtaagt 4981 ggaaattgcg attataaaga caaatatcct aaagaaggaa ttatagatat agagggcatt 5041 agaatatttt ttactcatgg tgatttatat ggtgttaaat atgggttgaa taatatttat 5101 tataaaacaa aagagttaaa agcagatata gctctttttg gacatactca tatttcaatg 5161 atagaaaaat atgatgatgt aatattaatg aatccaggta gtttgtcatt accgagaagt 5221 aggggaaggt atattggatt tattaaggtg gaaaaagggg aaaatcccag tgtttatcta 5281 aaggaaatgg gtatataata taaaatatat gatatgaatt taactaaata tataaaaaaa 5341 tataataatt ttttaaaaaa gtattgacga attagtttag atattgtaga atagtcattg 5401 tcgtcaggag ataacaacaa tgactccggg gtgtggcgca gatgggagcg cgcgtggttt 5461 gggaccatga ggtcgcaggt tcgatccctg tcaccccgac caagttgaaa atgtaatatt 5521 gcgggtgtag ctcaatggta gagccctagc cttccaagct agttacgtga gttcgattct 5581 catcacccgc tccattaaca ttaacaacta attaatcctt gatgaatgtt aaaagtgatt 5641 taaacatgag aatgaaaaag ttacttgaca taattcgaag aataacttat aatgataaag 5701 gttcttcggt taaagagttc aaaagtggtt ttgaaggttt gaaaaaataa tcttaaaaaa 5761 acttgacaga acaaacctta tgaattaaaa taataaacgt tgtaacaaga gatacaaaaa 5821 aataaaatat gcgtctttag ctcagctgga tagagcaacg cccttctaag gcgtgggcca 5881 ggggttcgaa tcccttaaga cgcaccatta tctcggggtg tggcgcagat gggagcgcgc 5941 gtggtttggg accatgaggt cgcaggttcg atccctgtca ccccgaccaa ttacaacaaa 6001 aaaataaata tgcgggtgta gctcaatggt agagccctag ccttccaagc tagttacgtg 6061 agttcgattc tcatcacccg ctccactaaa ataaaatatg cgtctttagc tcagctggat 6121 agagcaacgc ccttctaagg cgtgggccag gggttcgaat cccttaagac gcaccattat 6181 ggtgaatgta gttcagttgg tagagcgcca gtttgtggca ctggttgtcg tgggttcgag 6241 tcccatcgtt caccccatat tgggatgtcg ccaagcggta aggcaatgga ctttgactcc 6301 attatgcgta ggttcgaatc ctgccatccc agccaatatg tggttcacta gctcagtcgg 6361 tagagcacat gacttttaat catggtgtcc cgggttcgat tcccgggtga gccaccaaaa 6421 aaaatgcaga tgtggcggaa ttggcagacg cactagactt aggatctagc gctttacggc 6481 gtgggggttc gactcccttc atctgcacca aataagcaga agtgactcaa tggtagagtg 6541 ccaccttgcc aaggtggatg ttgcgggttc gagtcccgtc ttctgctcca aaaaaaaaat 6601 taaatatgcg ggtgtagctc aatggtagag ccctagcctt ccaagctagt tacgtgagtt 6661 cgattctcat cacccgctcc actaaaacaa tatgcgttat tagctcagtt ggtagagcac 6721 ctgactctta atcagggtgt cccgggttcg atcccctgat aacgcaccag atgaatggtg 6781 aatgtagttc agttggtaga gcgccagttt gtggcactgg ttgtcgtggg ttcaagtccc 6841 atcgttcacc ccatgtaatg ggatgtcgcc aagcggtaag gcaatggact ttgactccat 6901 tatgcgtagg ttcgaatcct gccatcccag ccaattacat aattaaataa atatggttca 6961 ctagctcagt cggtagagca catgactttt aatcatggtg tcccgggttc gattcccggg 7021 tgagccacca aaaaatgcag atgtggcgga attggcagac gcactagact taggatctag 7081 cgctttacgg cgtgggggtt cgactccctt catctgcacc aaataagcag aagtgactca 7141 atggtagagt gccaccttgc caaggtggat gttgcgggtt cgagtcccgt cttctgctcc 7201 aaaaaaatta aatatgcggg tatcgtatat cggtaatact ccagccttcc aagctggaaa 7261 ggtgggttcg attcccacta cccgctccat ttaaacaact gataacagtt gtttttttta 7321 tttatattta ataagcatct atagctcagc tggatagagc gttggacttc gaatccaagc 7381 gtcgcaggtt cgaatcctgt tagatgtacc ataaacatag taataccaat agtttataga 7441 cagtataaac tattggtgtt ttttttatac ttatatgttc attttaatat tggtgtttat 7501 taacttagat atattttaaa ataatgataa tatatgaata attaaaattg ccagagtaaa 7561 tttatttaaa atactattat aattttattt aaactaaagg ctgtagtctg tatgtatcat 7621 ttaatgttaa ctaataatac aagtagagtt taaattatat aaatctttgt ataagatgga 7681 attataaata atgaagaatt tattaaataa aatattatat aggtttttag taatattttt 7741 aactatatta ttgtttttaa taattgttgt aactatgctt atgcatatag tatacataaa 7801 ataaatagta agagtgaaat aagatttgaa ttagataagc ttatgagtga aaacaatatt 7861 taggatataa aattattttt agaaactaat ctatttatga aaacttcgaa ttatttatca 7921 aaagacttta gatatgttaa tttcaattta aataaaagaa tttatggagt aaaagataaa 7981 ataagtgatg gagaaatagc aattaatttg gtaaactaaa tttttagtga gccattaggg 8041 aaaatatatg taaaaattat tttagtgaag aatctaagaa agaagtacaa gtattaactt 8101 cttaaataat agataatttt aaatgtagaa taaacaattt ggattgcatg actggatata 8161 cgcaagaaag agaaataaaa aatttaataa tgttaatgta tgatatccag aggtgtgtac 8221 aaattataca caattaataa taaaaagtca caataattgt ggatgtttat tagaaaacgt 8281 attaaaaata tgtaatttta aattaaagga ggaattatcc ttattgcata aagaagttga 8341 atacaattaa tgggagatgt tacatcaaac agttaatgca tattataatc caactaaaaa 8401 tgaaatagta tttctatcag cgatacttca aaatccattt tatgatataa aaaatagtaa 8461 agttcaaaat ttagtaggta ttggagcagt tattggtcat gagttaacac atgcatttga 8521 taatacgggt tctaaatttg atgaatgtgg aaatttaaat aatttatgta cttataaata 8581 ttatgaagaa tttaatatta gaagtaagaa cgttattgat tattattcac atattcaaat 8641 taatagtggg gaatttgtta atggaaaact tacagttggt gaagacgtaa gtgatttttt 8701 gggggcaagt ataatagata tagctaatag catcaataat gctaatttaa aggagttatt 8761 taaaaactat gaaattattt ggagagaaat aagtacgaaa taaatggaat tacatctttt 8821 aaaaaatgat gtacattcgc ctaagaaggt aagagttaat actgtactaa gtcaatttga 8881 agatttttat aatgcatatt gtataaaaca aggaggcgat atgtatatat cacaatagaa 8941 tataataaaa gtgtggtagt aagttgataa tatggtagaa acatggccta gtgtatcagt 9001 atgtggataa ttaagcaaaa tataataaat aataataaaa taaagatatt ctctaataac 9061 agaaatttag atatatattt acattatctg atatgataga ataaatctcg tcgctgaggt 9121 gacaacgaac aacgctatta attatgttta aataaaacat gaaaaaaagt gttgacacaa 9181 attgagataa atgataatat taagaagtcg cttgagtgcg acagattaaa acaaaagttg 9241 acaataaagt caaccgagaa aatttggtct ttgaaaattg aacagaaatc aagaaacatt 9301 aaaataaacc agcaattctt tatttgagta agtcaagatt aaacttttta ttgagagttt 9361 gatcctggct caggacgaac gctggcggcg tgcctaacac atgcaagtcg agcgatgaag 9421 cttcttcgga agtggattag cggcggacgg gtgagtaaca cgtgggcaac ctgcctcata 9481 gagagggata gcctttcgaa aggaagatta atacctcata agattgtagt ttcgcatgaa 9541 acggcaataa aaggagtaat ccgctatgag atgggcccgc gtcgcattag ctagttggta 9601 aggtaatggc ttaccaaggc gacgatgcgt agccgacctg agagggtgat cggccacatt 9661 gggactgaga cacggcccag actcctacgg gaggcagcag tggggaatat tgcacaatgg 9721 gggaaaccct gatgcagcaa cgccgcgtga gtgatgaagg tcttcggatt gtaaaactct 9781 gtctttgggg acgataatga cggtacccaa ggaggaagcc acggctaact acgtgccagc 9841 agccgcggta atacgtaggt ggcaagcgtt gtccggattt actgggcgta aagggagcgt 9901 aggtggatat ttaagtggga tgtgaaatac tcgggcttaa cctgagtgct gcattccaaa 9961 ctggatatct agagtgcagg agaggaaagt ggaattccta gtgtagcggt gaaatgcgta 10021 gatattagga agaacaccag tggcgaaggc gactttctgg actgtaactg acactgaggc 10081 tcgaaagcgt ggggagcgaa caggattaga taccctggta gtccacgccg taaacgatga 10141 atactaggtg taggagctgt catggcttct gtgccgccgc taacgcatta agtattccgc 10201 ctggggagta cggtcgcaag attaaaactc aaaggaattg acgggggccc gcacaagcag 10261 cggagcatgt ggtttaattc gaagcaacgc gaagaacctt acctagactt gacatctcct 10321 gaattactct taatagagga agtcacttcg gtgacaggaa gacaggtggt gcatggttgt 10381 cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt 10441 agttgctacc atttagttga gcactctagc gagactgccg tggttaacgc ggaggaaggt 10501 ggggatgacg tcaaatcatc atgcccctta tgtctagggc tacacacgtg ctacaatggc 10561 tggtacaaag agatgcaata ccgcgaggtg gagctaaact ataaaaccag tctcagttcg 10621 gattgtaggc tgaaactcgc ctacatgaag ctggagttgc tagtaatcgc gaatcagaat 10681 gtcgcggtga atacgttccc gggccttgta cacaccgccc gtcacaccat gagagttggc 10741 aatacccaaa gttcgtgagc taacccgtaa gggaggcagc gacctaaggt agggtcagcg 10801 attggggtga agtcgtaaca aggtagccgt aggagaacct gcggctggat cacctccttt 10861 ctatggagaa atctagttaa catgatgttt aactagtaat taaaatatac ttactttgaa 10921 aaagaaggtt taatttaatg tagattctgt tcaattttga aagactaagt ctttcaaaat 10981 gagggcttat agctcagctg gttagagcgc acgcctgata agcgtgaggt cgatggttcg 11041 agtccattta agcccaccat tgttctttga aaattgcaca tagaatacga agtttaaaga 11101 agattaatgc aaaagtcatg aaaatgatta agtaataaga ttcaataaat aagtatattg 11161 tatataatac aacaagccaa gaatatattc tttgtataaa taagaactat tcattaattg 11221 ttaaaattaa attaataggt caagctacaa agggcgcatg gtgaatgcct tggcatcagg 11281 agccgatgaa ggacgcgata agctgcgata agcttcgggt agacgcacat agtcagagat 11341 ccgaagattt ccgaatgagg aaactcacat gggaaacccc atgtatcgta aagtgaatac 11401 atagctttat gaaggtaaac ccagggaact gaaacatcta agtacctgga ggaagagaaa 11461 gaaaaatcga ttttcttagt agcggcgagc gaaagggaaa gagcccaaac caaagattta 11521 tctttggggt tgcggacaga acattaacga gaaattatag ttaaccgaac acaactggaa 11581 agttggaccg tagggggtaa tagtcctgta ggtgaaaatt ataatgatca agttctgatc 11641 cagagtacca cgagacacgt gaaaccttgt gggaagcagg gaggaccacc tcccaaggct 11701 aaatactacc tgatgaccga tagtgaagca gtaccgtgag ggaaaggtga aaagaacccc 11761 gggaggggag tgaaatagaa cctgaaacca tgtgcctaca accgatcaaa gcaccttatg 11821 tgtgtgatga tgtgcttttt gtagaacgag ccaacgagtt acggtatgta gcaaggttaa 11881 gtacttaagg tacggagccg aagggaaacc gagtcttaat agggcgacta gttgcatgct 11941 gtagacccga aaccgggtga cctatccatg gccaggttga agcgagggta aaacctcgtg 12001 gaggaccgaa ccacgttgct gttgaaaaag catgggatga gctgtggata gcggagaaat 12061 tccaatcgaa ctcggatata gctggttctc ctcgaaatag ctttagggct agcgtcggaa 12121 aatgtgagta ctgggggtag agcactgaat gggctagggg gcatagcgct taccgaacct 12181 tatcaaactc cgaataccag atactatcag tccggcagtc agactgcgaa agataagttc 12241 cgtagtcaaa agggaaacag cccagatcgt cagctaaggt cccaaagtgt aagttaagtg 12301 gaaaaggatg tgggatttct aagacaacta ggatgttggc ttagaagcag ccactcatta 12361 aaagagtgcg taatagctca ctagtcaaga gatcctgcgc cgaaaatgtc cggggctcaa 12421 acttaccacc gaagctacgg gttcacacaa tagtgtgagc ggtagaggag cgtcgtaatc 12481 gggctgaagt cgtaccgtaa ggagcggtgg actgattacg agtgagaatg ttggcattag 12541 tagcgagatg tgggtgagaa tcccacaggc cgaataccta aggtttcctc aggaaggttc 12601 gtccgctgag ggttagtcgg gacctaagct gaggccgaaa ggcgtaagcg atggacaatc 12661 ggttgatatt ccgataccac tattatcgtt attatcgatg gtgtgacgga gaaggatagg 12721 atgtgctagc tattggatgc tagtctaagc gtttagggag ttagaatagg caaatccgtt 12781 ctaacaattc tgaggcgtga tggggaaggt tctaaggaac cgaagtatct gattccatgc 12841 ttccaagaaa agcatctaga aagagaaata gtgcccgtac cgcaaaccga cacaggtagg 12901 tgaggagaga atcctaaggc cggcggaaga attgcagtta aggaactagg caaattgacc 12961 ccgtaacttc gggagaaggg gtgcctgcga gagcaggccg cagagaatag gcacaagcaa 13021 ctgtttaaca aaaacacagg tctctgctaa agcgaaagct gatgtatagg ggctgacgcc 13081 tgcccggtgc tggaaggtta aggggaacac ttagcgtaag cgaaggtgtg aacttaagcc 13141 ccagtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct tgtcaggtaa 13201 gttctgaccc gcacgaatgg cgtaatgact tgtgcactgt ctcaactgca aatccggcga 13261 agttgtagtg cgagtgaaga tgctcgctac ccgcgattgg acggaaagac cccgtagagc 13321 tttactgtag cttagcattg aatttcggta ttgtctgtac aggataggtg ggagactggg 13381 aaatcagagc gtcagctttg atggagtcat ccttgggata ccaccctgat agtactggaa 13441 ttctaactgg atgccatgaa tctggtgaca ggacattgtt aggtgggcag tttgactggg 13501 gcggtcgcct cctaaaaagt aacggaggcg cccaaaggtt ccctcagaac ggtcggaaat 13561 cgttcgtaga gtgcaaaggc ataagggagc ctgactgcga gacctacaag tcgagcaggg 13621 acgaaagtcg ggcttagtga tccggtggta cctcgtggga gggccatcgc tcaacggata 13681 aaagctacct cggggataac aggctgatct cccccaagag ttcacatcga cggggaggtt 13741 tggcacctcg atgtcggctc gtcgcatcct ggggctgaag taggtcccaa gggttgggct 13801 gttcgcccat taaagcggca cgcgagctgg gttcagaacg tcgtgagaca gttcggtccc 13861 tatccgtcgc gggcgcagga aatttgagaa gagctgtcct tagtacgaga ggaccgggat 13921 ggaccgacct atggtgtacc agttgtttcg ccagaagcat agctgggtag ctaagtcggg 13981 acgggataaa cgctgaaagc atctaagcgt gaagcctcct tcaagatgag atttcccata 14041 gcgtaagcta gtaagacccc ttgaagacta caaggttgat aggtcagagg tgtaagtgtg 14101 gcaacatatt tagctgactg atactaatag gtcgagggct tgaccaatac ataattttta 14161 tatacaattt atgtgcaatt ttgaaagaac aatctttcaa ttagtattcc gcgatagctc 14221 aatggtggag cactcggctg ttaaccgata ggctggaggt tcgagtcctc ttcgcggagc 14281 caatttgata ttagtaaagt cgattagatc ggcttttttt tattgtctaa aattatttgt 14341 atacatgtaa taattttgta acaaaagtaa aaatactgta ttatataatt atatatgtag 14401 taatttgatg aactgaataa gtggacaaac ttatactaca ataaaagatt atgggggata 14461 acaataaatg agtaacaatg ttaattatag aagaagacgt gatgggaaaa acaaaaaaaa 14521 gaaaataata ttattttctt caatagtttt agtggtaata gtatctggaa tgctatcagc 14581 taaatatata catagtaaaa gtattaatgc tgatgcaagt gaacgtacaa ataataacga 14641 aattataaat gaaaataaag tagatgcagc tccaaaggaa gaacttaaat tagacaattc 14701 aggatattta actgcagaag aagatccaaa tgcagattca gcagcttttg tagaaaagta 14761 tttatatgaa caaagtcttg gtaaaatgcc agaaggtgct gatggtcata aagttgcata 14821 tttaactttt gatgatggtc catcagaaag tgtaactcca gaagttttaa aagtattaaa 14881 ggaaaaagat gttaaagcta cgtttttcac attaggaaaa tctataaatg aaagtgatag 14941 aactaaggag ttattaaaag aaatagtaaa agatggacat gctgtagcaa gtcacacata 15001 ttcacatgac tataaatatt tatatccaca tagaacagtt agtattgaaa attttatggg 15061 tgatatagaa aaaaacaatg aaacatttag acaagtttta ggaaaagatt ttgtaactaa 15121 aactattaga tttccaggtg gacttatgtc ttggaacggt caagatgcta taaaagagaa 15181 gttacaagaa ggtggataca gctatattga atggaatgct ttatctaagg atgcagaagg 15241 taaaacaaaa gttgcctctg agttattaga agaagtaaag aaaagtgttg ctggaagaga 15301 aaaggcagtt atattaatgc atgatgcatc aggtaaggac gaaactgcta aagcattacc 15361 tggagtaata gactatttaa gagaacaagg atatgagttt aaaagtataa aataaattta 15421 atgttatttt tataaatata taaagagact tttaaagtct cttttttatt ataataaaat 15481 ggtaagtagg tataatgtat ataggaggta tttattatgc gtagaattct attggtggaa 15541 gatgaagaaa gtataagggg atttataaag ataaatttaa aaagaaatga ttttgaagta 15601 atagaggctg aatgtgggga agatggactt aaggcggctg aaaaatttag tatagattta 15661 gcagttttag atgtgatgct tccaggtata gatggtttta aggtatgtga tgaattgaga 15721 aaaagatatc ctaaaatggg aattataatg ttaacagcac gtactcaaga tatggataaa 15781 ataatgggat tggaatatgg tgctgatgat tatataataa aaccgtttaa tccattagaa 15841 ttaattctta gaattaaagc aatattaaga agaactgggg atgaaagtca agttaaagaa 15901 aatattgata agttaattag agaaccgttc ataatagact tatattctca aaaattattt 15961 aaagataata tagaaataga tgttactcca aaggaatatt tgcttatgaa attgttttta 16021 aaaaatccta ataaagcatt ttcacgagat gaacttttaa atttaatatg ggggtatgat 16081 tattttggtg atcctaaatt aatagatgtt aatattagac gtctaagatc taagatagaa 16141 gatactccat cggaaccaga atttatagaa actatatggg gtaaagggta cagatggaag 16201 ggataataaa atgaaaagta ttaaaaatac actaattaga agttttatat ttttgatatt 16261 atttattgtt atatgtatga atatactttt aggcacactt gtaaagaagt attattacga 16321 taatgctgaa actttgttaa gaaatcaaat agaaatagca actaattttt ataataaata 16381 tttatataga tcaagtttaa ttgaaaatat atatgataat gttgattcat tttggaataa 16441 aaacaatgca gaggttcaaa tattagatga aaaaggaaat ctattaatgg attcaatagg 16501 cgtctatgat aatgatttac atgaaaaacc tgatgttaaa aaggctataa atggtgaaag 16561 tggaagctat gttggaaatg taagctacag taattataaa gtaatgtctg tttctgagcc 16621 attgttaaat gataatgaag ttataggaat aatcaggtat gttatatcgc tagaagaaat 16681 taataatgag ctaaaaaata tagtgttctg ttttatgtta atatctatac tagtattatt 16741 tttaggtata attattagtt tgattttatc taataaaatt ataaatccaa taaaaaaatt 16801 aactgatata tcacaaaaga tggctaacgg aaatttaaat gttagaaaca atataagtgg 16861 tgaaggggaa gttgctcaac ttgctaatac attagattat atggcagaag aaattataaa 16921 aagagaaaaa ttaaaagacg attttatatc atctgtatct catgaattaa gaacaccatt 16981 aacttctata aaaggttggg ttataacgct tcaagatgat aatactgata aagaaacatt 17041 taaattaggt tttaatatat tagaaaaaga aactgataga ttatctaata tggtagagga 17101 attattagat ttctcacgtc ttataaatgg aaagatgcaa ttaaaaagag aaaaagtaaa 17161 tgtaatggaa ttaatagaat atatagagag ttatatgata cctagggctt taaaggaatg 17221 tattaatttt aatgtattat ctaatttaga taataaaata tattatttag atatagatag 17281 aatgaaacaa gttttaataa atttaataga caattcattt aaattcgtaa ataaaaacgg 17341 gaatgttaat gttattttta atgaaggaga agatgattta aaaatagttg tggaagataa 17401 tggatgtgga ataagtaaaa gtgatttacc aagggtaaaa gaaaaattct ataagggtgc 17461 taattcaaaa tctcaaaatg ggatagggtt atctatttgt gaagaaatag ttaatcttca 17521 taatggttat ttagatatag taagtgaaga aggcaaaatg acaagaatta ctatattaat 17581 tcctaatata agggagacag atgtatgaaa aaatttataa atatattttt agttgttctt 17641 atatcttttt ttataacagg atgtaatgag gtttcgcaaa ataaaattta taaaattaag 17701 gcaccacaaa acaattcttt aagtattaaa ggagtatgga gagttgataa ttataaggtt 17761 ttagatgatg acatatattc acttaataat agaaaatttt tagtgggaga agatattgaa 17821 atatgtaatg aatatatagc attaaaaaat attgaatata gtaatatttc atataaatta 17881 aagttagtaa aagatgatta tgttatatcc tatgaggaaa aatataatat aggaaattta 17941 aatttaaata aagaaaatta tgaagtaata tcagtattta atgataataa tataatattt 18001 gaatttataa aagatacttc agaaagtgga cttatatttt ataatggagc tttatataat 18061 gtaagtttag tagggcaaat taatgaggat atagaaaata atattaaaaa agaagaacat 18121 aaatcagata gtagattggt taatgattat aattctcctg tgggagttta cctaggaata 18181 aagtcaaaaa ataaggagga caatacagag gagtataaaa cattatatgt ttcctttaag 18241 gatggaaaac tacaacctat aagagaaaaa gaaggtttaa tagttccacg tatgaatgga 18301 atatggtata taaataaaga atttgtagaa aaaaatgatt attattatga atactttgat 18361 gctaagccaa ttaataataa agagtttgca aatagtagta ataaaaaaat agaaaatata 18421 gataaaaaca aatatataag tataaatttt gttggtaatg attatatagc tactgaggtc 18481 tatgaaggga aaaattttga tggagaatat ggaaagtatg aagttttacc aatagataat 18541 ataacatcaa atataccaat tgttataagt gatatattcc ctgctgatga tagtaaatct 18601 tttaaacaaa cttatgataa ggttattaat agtttttctg atgaagataa acaaaagtat 18661 agtccatata tgaattatag caatttttca cttaaaagag taaatggaaa atggactgtt 18721 gtaggtaaaa tatcacctgc ttatggaata gatggaagtg gatatgatta tactttaaat 18781 ttaaagcaaa ataagaagtt actaaattat gattctcttc taattccatg gaaaacatta 18841 aagcgagaat taccaggaat taaagatgca tttacttctc ctaataaaag aattgcatta 18901 attttaactg aaaaagcatt gcttatagat gaaattgaaa attataaaat aaacaatgtt 18961 ccacttgata taatagatat gaatgaaaat gatgagatta taatggcaga atggtgtata 19021 ggtgactatg ttgataattg ggaaaaacca tttttaaatt aggctatatt ttattgtaaa 19081 atatatacaa gtaaaatgga tggaataatt gaacttatga atactaaata tgaatatagt 19141 ttaattagaa taccattttg tctaataaac atatgagtaa gtatctaaaa tatagtctga 19201 aattaagata gacttactat aatatggata gtattatagt agataatatg agattataat 19261 aatagtacat ttaaaatttt ttatagtatt tatattgtag tatgagttta tttttatata 19321 aaataacgaa agtataaggg aggatttata tgttagaaaa aagcattgta tcacaggtat 19381 tagcaagatg cttaataact gggggggatt ttgcagaaat ttttgaagat gattctgtaa 19441 ataactctat atcattaata gatggaaaag tagaggatgc cataggtgga agaaactacg 19501 gaattggaat tagaattttt aaaggattaa agagcgtata tgcatataca aataataata 19561 gtttagattc tttattagaa acagcttata gagcagcatt agctttaggt aatgcaaatg 19621 aagaagaaaa gaatattata ttaaatgaga aaaagataca aacaatacat ccaataatgt 19681 tttatcctaa ggatgtaaac tataataaaa aaatagatat tttaaaatta gcttataata 19741 gtgctaaaaa ttataatagt gaaatttcac aggttataac aagttatggt gataaggaac 19801 aaaatatctt aattgctaat agtgatggtt tatatataga agataaaaga attagaacaa 19861 ggcttggaat aaatgccata gcatctaaag gatcagaaaa tcaaacagga tttgaaggtc 19921 caggaagata tatgggaatt gaaatgtttg aaagtataga tcctgaatac catggaatgg 19981 aagcagcaag gatagctcat acaatgcttc atgcaaagaa ttgtccagct ggtaatatgg 20041 cagttgcaat agataacgga tttggtggag taatatttca tgaggcatgt ggtcatgcat 20101 tagaagcaag ctctgttgct aaaggtaatt ctgtttttgc taataaatta ggcgagcaaa 20161 tagcatcaac taaagtaaca gctatagatg atggtacaat agctaatgct tggggatcac 20221 ttaatataga tgatgaagga aataaaactc aaaaaaatat tttaattgaa aatggcatat 20281 taaaaggata tatgattgat aaattaaatg gtagaagaat gaatatgaaa ccaacaggta 20341 gttcgagaag acagagttat aaatatcaac ctacatcaag aatgactaat acgtatatag 20401 caaatggaat ggataatcca gaagatataa ttaaatcaat ttcagatggt ttatatgcta 20461 agaagttagg tgggggttca gtaaatccta taactggaga atttaacttt gctgtacaag 20521 aaggatattt agttaagaat ggtgttatta aggaaccagt aaggggcgca agtcttattg 20581 gaaaaggtag cgaagttctt atggacattg atatggtagg taataattta gaattagctc 20641 aaggaatgtg tggttcttct tcaggaagta ttccaactaa tgtaggtcaa cctatgatta 20701 gagttaagaa aatgacagtt gggggtagat agtacatgga atttaatttg tttaaagaga 20761 aactaatgag tgaagctaaa aaagcaggat ttgatgaatg tgaaatatat tattctgatg 20821 cggaaagttt aagtataaac atttatgatg gagacgttga aaagtataaa ttaaataatt 20881 catttggatt atcatttaga ggaaaaataa atgagaaaat gggatattca tacactgaga 20941 tattagatga agattctata agtactctta tagaaaatgc aaaaggtgca gcattagtta 21001 tagaaaatga tgatactcaa tttatatatg aaggtgataa tgagtataaa gaaattaatt 21061 gttataaaaa tgaattagat aatataaaac ctgataagct tataaaatta gctttagaaa 21121 tggaacgtga atgcaaaaag caatgtgata aagttgttaa ttttggtggt tgtggaatag 21181 gatatggaaa atctagttat ggaatattaa attcaaaggg gttagattta tcaacttcaa 21241 gaaatcactt aacagcttac gtagttccaa taatcgaaga taataatgaa aaatatgatg 21301 gcatgggata tgttattgca aagggagaag ctgatattaa tccagaaaaa ttagctaaag 21361 atggattaga agaggctctt tcaagaattg gtggaagaag catagaatca ggaaaatata 21421 aagtggttat aaataatgaa gctatggtat cattacttgg aactttttca ggaattttta 21481 atgctgaaca agcacaaaag ggattatctt tattaagagg taaagaagga gaaattatag 21541 cttcagataa agtaacttta atagatgatc ctcatcttga agatggactt ggaacaacag 21601 catttgatga tgaaggtgtt gcaacttata aaaaggaagt tataactaat ggaaaactaa 21661 atacattatt atacaattta aagacagcac ataaggctaa tgttaaatct acaggtaatg 21721 gatttaaatc atcttatgca tctatagtag ggattagccc aacaaatttt tatataaaac 21781 caggaaagaa agactttgag gagatatgta aagaggttaa caacggagta ataataactg 21841 aatttgcagg acttcattct ggggctaatt ctgttactgg agatttttct ttggcatcta 21901 agggatttat gattgaaaat ggaaagaaga cattcccaat agagcaaatt acagtagcag 21961 gaaatttctt tacattaatt aaagatgtag aagaaatagg aagtgattta aagttcccta 22021 tgagtagtgt aggttcacca tgtgttgtta taaaggaatt atcaatagca ggaaaataaa 22081 taatatattg tcttataaag ttgtgctgat attatagtat aaagcttgtg ggctgaggaa 22141 tttactttaa gaacactaaa atagatacta gtctaattaa tgcattatcc taatgaaaca 22201 ttgtgacaag caattaatta aacaaatatc tattaagaat tataaaaaat aaattacaat 22261 accactatgc aattatacta aaatatcaac atttatttaa aaagatattg ataatgtagt 22321 agatttattg aatagacata aaaaatagaa ggactaattt tgtagtcctt ctatttttta 22381 tttagctatg ttttgaatag gtgttaaaaa gatagcctaa ttatatagat tattattttt 22441 taaagtaatt cgcccttatc attttgtctg ataaatctaa tatgtttttg tatgtttctt 22501 tatcttcatc agaaagggta ttttggtctt ttatagtacc atctgttaat atagcgaatg 22561 atttatttgt atttagaaga tttcttccta aagcagtgtt ttgatatttt tctttatcta 22621 taccaagcat ataaagtagg gttggcataa catcaatctg tccaccatat aaatcaaatg 22681 tttttccagt attaatagaa gtatcataga ttaaaagtgg aactacaggg ttacccgtgt 22741 ctagatacca atcttcttta ttagataatt tttcaattcc attgttataa tatttatgaa 22801 cacctgtatg atcacccata atagctatta cactattttc taataatcct tcactatgta 22861 atagttttaa gaagttacct atttgagcat ctgtatagtg taagctttca aaatatccac 22921 ctagctcact agcatctaat tcaggatcaa gtcctaattc tctatactct tttggtatat 22981 caaatggacc atgacttgtt aatgttactg taagagcata aaatggatta gattgttctt 23041 ttaacattgg aactacttgt ttaaagtagc ttgcatcact tatacccatt ccaattgttt 23101 catctgcatt gaatgaatag taatcgttaa atttatcaaa tcctattcct ttaagtccgg 23161 cagaataatt ccagaaagaa cccttatcag gatgtatagc aatactgcta taactatttt 23221 tttctaatat atcaggtaaa gaattataag tattatttgg atatctaaag aaagtacttc 23281 ctcttcttag tggaaacata gatgtattaa ccattaaatc actatcagaa cttgtacctt 23341 cattaacttg ttcaaataca ttaggaaaat aaaagccttt agatgttaaa ttgttcaata 23401 caggagtaat ttctttgcca ttaatgcttt tatttataac aaaactttct aaagattcaa 23461 cttgaatata aattagattt ttacctttag atataccaaa gtaatcattg ttaggtaagt 23521 tttcattctt catattaaat aatttattta aattattttc atcttcaact gtaaattcat 23581 atggttttga atcacgataa actgtatata aatcaaatat atgatatcca attggtgaaa 23641 aatatctagc tgtgtttgtt gggtcgtaat tatcatataa ataggaatct ttaacatctt 23701 tattatttaa aatatgtata ttaaaaggaa cataacctat aaataatatt ggcataataa 23761 aagttataag aaaagttttt atcgctctct tatttatttt agatacatat tttctagtaa 23821 agtaaacata aattccaaat aaaaagaaat ctattataaa gataacgtct aaaggactaa 23881 acatagaata tactgcccca gacaaattat ctaaatttgc agtttgagtt gcaataagaa 23941 tagatggaac tgttaaaaat cctctaaagt aacaaacatc taatacgata attgcagtta 24001 agagtatatt tattgtaaaa agatatatta ttcttgcttt acctttaaat aaaagagaaa 24061 aacttatgaa tattaaaatg aaagctagat aataattaaa aaaaggtcta gcatagtcat 24121 aaccagtatt gaaattaaaa ctataggggt tactacctgt aataaatcct tgaaaaaata 24181 tacatttaag gaatatagaa attaaaggaa ataaaaatag tatcaattga tttagtctac 24241 ttttattaag gaaatcagta attttatttt tgttagaatg cataaattca cctcaatcta 24301 ctaattaata aaaaaatgat aatattatat tagtaattat tatcatttag ttaacatctt 24361 atattataca taaatacata aatcaaacaa cccatataaa attaaacatg atataattat 24421 cttatcttaa ttttataatt aatataaact aagggggaga aattttatga aagaaataga 24481 ttgtagaggt ttgtcttttc ctaagactat aagaatggta aaaaaatatt ttaattctat 24541 aggtgaaggt gaagcaatag ttattataga aaaacaggcg gataattcta atatcgctaa 24601 tcttgctatg aacttaggat accatgtaga tgtagaagaa aatgatgaaa atattcatat 24661 atttatagaa aaaagaggtt gcttagaggc aatagatgaa actgtatttt cagttttaat 24721 aacatctgat aaatttggat caggtgattc taaattagga aaaatattat taaacgatta 24781 tttaaatgca ttaagtgatg caataaagct tcctaaaaat attatatttt taaatgaagg 24841 cgtaaaagtt tttcaggatg tatcagacaa tattaattgg ttagaaaata taaaattatt 24901 atctcaagaa ggagtaagta tattagtaca tgataaatct ttagaatatt ataaattaga 24961 tatttctaat aatttttcag aggttattga tatgagtgac ttagtagata taataaatga 25021 atctaataac ttaataaagt tataatatgt gattagtata tttggaggaa atataatgtt 25081 agaatatgat ttagttgtga ttggtggagg aatagctgga atgacggctg ctttaggtgc 25141 agcaagagaa ggcataaata atatattaat agttgaaaga gaacatagtt taggtggaat 25201 actaaatcaa tgtattcata atgactttgg tgaaaagttc gtaggagaaa aagtaacagg 25261 acctgaatat atttttttta ttgaagaaaa attaaaaaag ttgaatatag atattaagct 25321 taatactaat gttatagaca taatagatga taacaaaata acttatgtta attcaataga 25381 aggaagtaaa gagataaata caaaggcaat aatattagca actggatcaa gagaagttta 25441 tacaggaagt gttatggttc caactcatgg gttaacaggt atatttacat taggctctgc 25501 tcatagattg attaatttag aaggatattt gccaggtaaa aagactgtaa taattgctaa 25561 aaataaatgg ggatttttag tggctagacg tattctaatt gagggtggaa gtgtagaagc 25621 tataataatt gaagaggaaa ttaaagaact aatagatgag gaaatcgaaa atttaataaa 25681 tggattttca ttagatatta tagaaaattc tagagtggta gaaatttatg gtgatagcag 25741 aataaataaa attaaaatat taaatttgaa ggaagatgta atttctaaaa tagagtgtga 25801 ttctttaatt ttatcagttg gatttagacc tgaaaataaa cttgctcaaa gtttaaagtt 25861 agatattaat aaaaatacat ttgttccaga aataaatgac tttaagactt ctaaagaaag 25921 tgtttttgct tgtggtaatt taatttatgg aaagttagct cttataatgg aagaaacaga 25981 tgggcttaat tgtggaataa gagcagctga atatattaaa aacataaatt aaaaataaga 26041 tacagcattt ttatacataa tttcattacc taatgaatta aggtgtattc catctaaata 26101 tatgtcacta ttatttaaag taattgaata aaaatctata taagagaggc tataattaac 26161 agctagattg attattgcct ctcttaattt aattaaattt tcctctgcat atgtataaaa 26221 tggagaggat gagaataatt tatttgccat agctcctatt attgaaggtg gaattcctat 26281 aacaacatta gagttaattt ctaaagaatc ttttatcatc aattctatat tctcaattat 26341 tgattttaca gttcttccta agagtaaatc attgctacca cacataataa atattttggt 26401 tggagtatat cttattacat cttcataata tctattaagc ataccaatac tagtatctcc 26461 attacagcca ttgtttaatg atgttacatt tatattattt tgaattttat agacccaaga 26521 atctttttta ggaacaccat atccaaaagt taaactatca cctaagaaaa taatatctac 26581 atgcttaatc at //