LOCUS NC_010723:5 21782 bp DNA linear BCT 25-AUG-2011 DEFINITION Clostridium botulinum E3 str. Alaska E43, complete genome. ACCESSION NC_010723 SOURCE Clostridium botulinum E3 str. Alaska E43, complete genome. COMMENT locus start: 371741; locus end: 393522 FEATURES Location/Qualifiers source 1..21782 /organism="Clostridium botulinum E3 str. Alaska E43, complete genome." gene 0..581 /gene="" /locus_tag="" /db_xref="371741..372322" CDS 0..581 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MINTHKLIAENILNNTNSKSIYLINDYRFIWGNIKPDCVLKYKM IKHYFIESIDMIIKKIEKLCSLSLQDVYYKMSVNKFSEELGVICHFICDYFCAPHYYR WEFKNTSQVKNHVMYEKDLAKIAKEFNSNGIITSNIDANNIKEFIYDLQNQYEGSMDF KNDLTYAYYACDSIVNMVLNKVFLNECSLSKVV" gene 706..1071 /gene="" /locus_tag="" /db_xref="372447..372812" CDS 706..1071 /gene="" /locus_tag="" /product="cadmium efflux system accessory protein" /translation="MNNETNFVESCKCNIIHEDTVIKVKDSLPQEETLYDLAELFKVF GDSTRIKIICALFESELCVCDMAALLGMTQSAISHQLRTLKSARLVKFRRQGKVIYYS LDDEHIKHIFDEGFKHITE" gene 1089..3350 /gene="cadA" /locus_tag="cadA" /db_xref="372830..375091" CDS 1089..3350 /gene="cadA" /locus_tag="cadA" /product="cadmium-translocating P-type ATPase" /translation="MENEIKLSLKGLDCANCANKIERKVNDMEDVYEADMNFSLGKLT VKLHENKDRDKVFNLIKDIVNKLEPDVIVINEKDNISYNLNTNETNHNNKCNKTCCNH DSCSSHNHEKHHVHSHDNQDNFIETEECEPNSKIKLFDKKKFFYENQIFIIGLILYII AVLFKENSYLNISIFVLSYILIGGDVLKTAFNNILIGEIFDENFLMTIATIGALAIGE YPEAVGVMMFYKIGELFQGYAVNKSRKSITSLMNIRPEYANVITEYGEKRVSPEEVNI DELIVIKPGERIPLDGIVVEGKGSVDTSALTGESLPREINIDDELLSGSINLSSVIKL KVTKIFSESTVSKILNLVENSSSKKAKTEKFITKFSRLYTPIVVFLAIAVAIIPPIII SGEVFSDWIYRALIFLVISCPCALVISVPLGLFAGIGGASKKGILIKGGNYIEVLKNV DTIVFDKTGTLTKGVFKVTEINSIDMKKEDFLRIVALGESFSTHPIAQSIVKEFNGIL EKRYVENYQELSGHGIKAIIEGKNVILGNYKLLEDNNINIEKVEKPGTVVYVVINNKY SGNIVIADEIKEDSIEAINKLKNIGIKKTVMLTGDNKIVANSIGKSIGVDEVKSELLP NDKVLEIEKLISSSTSKGKVMFVGDGINDAPVLARADIGIAMGGIGSDAAIEAADVVL MKDNPTALVDAIKIAKKTNAILWQNIIFALGVKVFVLVLGALGIANMWEAVFADVGVT LIAILNSMRSLKN" gene 3783..4415 /gene="" /locus_tag="" /db_xref="375524..376156" CDS 3783..4415 /gene="" /locus_tag="" /product="redox-sensing transcriptional repressor rex" /translation="MDKNKNISMAVIKRLPKYHRYLNELMKNDVDRISSKELGEKIGF TASQIRQDLNCFGDFGQQGYGYNVKELYTQINSILGLDKEYNAVLIGAGNIGQAIANY SRFDKLGIMITAIFDANPKLIGIKIRDIEIRDIDELGSFLKSDSVDIGVICVPKKSAQ KVSDELVNGGIRGIWNFAPIDLVVPEDVKVENVHLSESVSTLIYQLHQQR" gene 4764..5546 /gene="crt" /locus_tag="crt" /db_xref="376505..377287" CDS 4764..5546 /gene="crt" /locus_tag="crt" /product="3-hydroxybutyryl-CoA dehydratase" /translation="MELKNVILEKEGHLAIVTINRPKALNALNSETLTDLDTVLENLE NDSNIYAVILTGSGEKSFVAGADISEMKDLNEKQGREFGELGNKVFLRLENLDKPVIA AISGFALGGGCELSMACDIRIASEKAKFGQPEAGLGITPGFGGTQRLARIVGLGKAKE MIYTCDIIKAEEAYRIGLVNKVVSLESLMDEAKAMANKIIANAPIAVKLCKDAINRGM QVDIDKAVLIEAEDFGKCFSSEDQTEGMTAFLERREKNFQNK" gene 5627..6766 /gene="" /locus_tag="" /db_xref="377368..378507" CDS 5627..6766 /gene="" /locus_tag="" /product="acyl-coa dehydrogenase, short-chain specific" /translation="MNFQLTREQELVQQMVREFAENEVKPIAAEVDETERFPMENVEK MGKIGMMGIPFAKEFGGAGGDVLSYIMTVEELSKVCATTGVIVSAHTSLCASVINEHG TPDQKAKYLPELCQGKKIGAFGLTEPGAGTDAAGQQTTAVLDGDHYVLNGSKIFITNG GVAETFIIFAMTDKSQGTKGISAFIVEKSFPGFSIGKLEDKMGIRGSSTTELVMEDCI VPKENLIGKEGKGFGIAMKTLDGGRIGIAAQALGIAEGAFEEAVNYMKERKQFRRPLS AQQGLQWYIAEMDVKIEAARHLVYKAACKKQNGQPYSVDAARAKLFAAEVAMDVTTKA VQIFGGYGYTKDYPVERMMRDAKITEIYEGTSEVQKMVIAGSILR" gene 6784..7566 /gene="" /locus_tag="" /db_xref="378525..379307" CDS 6784..7566 /gene="" /locus_tag="" /product="electron transfer flavoprotein, beta subunit/FixA family protein" /translation="MNIVVCVKQVPDTTAVKIDPKTGTLIRDGVPSIMNPEDKHALEG ALQLKETLGAKVTVISMGLPMAKATLREALCMGADEAILLTDRALGGADTLATSKALA GVIAKLDYDLVFAGRQAIDGDTAQVGPEIAEHLNIPQVTYVQGVEAKGEGTLLVNRAL EDGYEKIEIKTPCLLTAIEELNEARYMNVANIFSTNDNEIKVMSADDIDVDKAELGLK GSPTKVKKSMTKEVKGAGEVVNKPAKEAVTYVLGKLQEKHYI" gene 7589..8596 /gene="etfA" /locus_tag="etfA" /db_xref="379330..380337" CDS 7589..8596 /gene="etfA" /locus_tag="etfA" /product="electron transfer flavoprotein, alpha subunit" /translation="MNIADYRGVWVFAEQREGELQKVSLELLGEGRKIADKLGVELTA LLLGNNIENLSKTLAEHGADKVLVADDKNLEHYTTDAYTKVICDLANERKPGILFIGA TFIGRDLGPRVAARLSTGLTADCTSLDVEVEDGALLATRPAFGGNLMATIACPEHRPQ MATVRPGVFGKVNTDGSNCTVEKVEVKLADSDVRTKVVEIIKAHKDVVDISEAKILVA GGRGMGSKENFTLLQELAEVLDGTVAGSRAAVDNGWLERDYQVGQTGKTVRPSIYIAC GISGAIQHVAGMQESDMIIAINKDETAPIMQVADYAIVGDVKKVLPELIAQAKAVKSA E" gene 8700..9548 /gene="" /locus_tag="" /db_xref="380441..381289" CDS 8700..9548 /gene="" /locus_tag="" /product="3-hydroxybutyryl-coa dehydrogenase" /translation="MKKVFVLGAGTMGAGIVQAFAQHGYEVIVRDIKDEFVERGIAGI NKGLTKQVAKGRMTEEVKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKREIFAEL DEICKPETILASNTSSLSITEVASATKRADKVIGMHFFNPAPVMKLVEIIRGMATSQE TFDAIKELTVAIEKNPVEVAEAPGFVVNRILIPMINEGIGILAEGIASVEDIDTAMKY GANHPMGPLALGDLIGLDVCLAIMDVLYNETGDTKYRAHSLLRKYVRAGWLGRKSGKG FYDYSR" gene 9708..10142 /gene="" /locus_tag="" /db_xref="381449..381883" CDS 9708..10142 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MLKETAIKYWDDKYDLNCAECLIYASNEEYDLNLSKDALKTMAA FGGGMAIGDVCGVISGAIAVIGIMFTDISGHKSPIVKKMTTEFINKFKNKLGSNNCIE LRKEYRKSKKEGTCIVMVETAADILESIVNRDNNFKLDSNKY" gene 10232..11158 /gene="" /locus_tag="" /db_xref="381973..382899" CDS 10232..11158 /gene="" /locus_tag="" /product="8-oxoguanine DNA glycosylase" /translation="MDYKSIETSENGVIIRGVKNFNLKHIFECGQIFRFEEIEDDNFI VIAFGKLIELVQKKDDVFIYNTTEKEFKEIWLNYFDLDRDYSIIKEELSKDELLKQSI EFGSGVRVLNQDPFEMLISFIISARNSIPSIRKTVNKISEQWGNKIEYKGKVYYAFPT IEQIKDAKLDEIKETGASFRSKYLIDTIENVHNSIGNKSNLSENEKELLNKYDLKYIK GLSDDECHAALQEFKGVGAKVADCIMLFSMGKTSAFPVDVWVKRAMMHFYNAEEGSLN KIRVFARNKFGKLSGFAQQYLFYYARENNIKV" gene 11320..12804 /gene="" /locus_tag="" /db_xref="383061..384545" CDS 11320..12804 /gene="" /locus_tag="" /product="iron-dependent hydrogenase" /translation="MFKFENQLIKLKHDVLSNIVRLAKEDNINKENLDKIPYEMLPGN EPQYRESVVHEREVLLERLKLASGFIPNGKGTDELVNIEDEKQILYVIKNACDMCPTK KFEVTDACRNCIAHKCQSVCNFGAITYVDGKAYIDPDKCKECGMCKKACPYDAIAEDM RPCKRSCPTGALDINSDKRAMIKQEKCVNCGACMAACPFGALEDRSLLVKIVKELTNN SNIYAVVAPAITGQLGPKTGYGQVKNAIKKLGFTDMVEAACGADAVTVHESNEFVERM ENGDPYMTNSCCPGFLSYIEKMMPDQVDRISGTVSPMVAAGRFIKANDKDAKVVFIGP CTAKKSEILRDSIKDAVDYVLTFEELLALFEGFNIDPANFYDIVVDEASIFGRGFGVG GGLTAAIENYIKDKGIDCEFKPVKVSGGAEIKKTMMMAKMGRLPGNFIEGMMCEGGCI NGSGKILSPMKAKSSFNKVNQQATMKNVLENSKIDDYKDIDLER" gene 13003..13698 /gene="" /locus_tag="" /db_xref="384744..385439" CDS 13003..13698 /gene="" /locus_tag="" /product="alkaline phosphatase synthesis transcriptional regulatory proteinphoP" /translation="MKILLVDDEESILNLIKMNLIFENYEVITAECGIDAINLFKSES PDLIVLDLMLPDKDGFEVIHEFQSINSEVPIIILSARDQLNNKLLGLQLGADDYITKP FDSRELILRIRAISRRINKAKAIGKNEIKNKTNDIIEKGFIKIIVPERRVFIDDKEVI FTHIEFEIILLMVQNPFKVFTREELLDKIWGYSFVGNTRAVDIHIKRIRQKLIGNEDV IKTIYGVGYRLEV" gene 13702..15117 /gene="" /locus_tag="" /db_xref="385443..386858" CDS 13702..15117 /gene="" /locus_tag="" /product="two-component sensor histidine kinase" /translation="MNWGIKGKIVIMNIFILIIAILSIYVVTIYTLYSRVINNSIDML RKESYTSQSFIMKYLETEDDFHVENVLNEMSPFIATYLSNNCKFRVQIYNNSSLIGDS DNYPNISKDDDVVTALKGNKSYIIRRIEESSYILFSSPIYYSDGTIGCIRYVYDLNNE NTIITNTILSMVLFAIVAIIFSSMMSNSFSNRIVRPIVSLKNIARKVSFGDFSKKISI NSKDEIEDLSNSFNIMSNNIEIMIENLKDEKETQKRFLDNVTHEFKTPLAAILGYSDL LLRVKEKKDIEQCVKYIVQSSNRLLKLVEQLLDLSRLNKNELEVKNENVDIKSIIETA AMMLNPRMNKFGIKLNMNLISKSVYADKEKTEQVILNLLDNAIKYSECTEIDIYMENN EDYEIIYIIDNGQGIPKEDLKNVFENFYTAHKALQKKYGGSGLGLAICKEFMEKQSGK IEISSLNGTTVKLSFKHAISN" gene 15142..15981 /gene="" /locus_tag="" /db_xref="386883..387722" CDS 15142..15981 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MINFNYKIVINLFVILVILLASIYVYLKSSIYNNLIVLDDKEQV MQHSSHSIPVKVELYSRRWGKLIINSNDEIKEFWNIVEAMPKSNNFYNSKIENSFNEI TGTIYYLDGEKGTLYLNNTLRIDDIYYGGNDSSAYINRIKNYINDIFCTPSVLSELIN DKNKITIVDVYNNTKKCGSNDKVLIKDEVMNLKRIIDNKKLEWAVANKGDLNYHIRIY REESEEFHDNKIEDDSNSYDVISLDIYENDYVIVRDYGDEIVNSFYMEGDLNNICDNL FNQ" gene 16002..17051 /gene="" /locus_tag="" /db_xref="387743..388792" CDS 16002..17051 /gene="" /locus_tag="" /product="ABC transporter, substrate-binding protein" /translation="MLNKRRGILLIFVLLIICILNGCSSNISSGKASSKEIPNLKNEN LVVYVAFNEDEAKVLLDGFKEKTGCNYTFLRYPTEELADKIKSQETLGEADIFLGGTA DAVELLKMNDCLEKYTINSSSEIPIEYMDSDGYWIGLYVEALSIAINEDRWEKEFNDI EKPKTLEELVNPKFKGEIVLADPRTSGTGYTLLSYLVQTMGKDDALEFFKKLKNNVGQ FTDSGFTPAKKVGMGEYLLTVNFINQQLIVKNSGFNIESIVPDNTGWTICPIAKIKDG KNKKASEAFMNYCVTKEAGISLKDFSMGFSTIPGVNYPNIEKDFTSYKLSKEYDFKKA AKDRKELLEDLEEIM" gene 17455..17739 /gene="groS" /locus_tag="groS" /db_xref="389196..389480" CDS 17455..17739 /gene="groS" /locus_tag="groS" /product="chaperonin GroS" /translation="MRIKPLGNRVVIKRLEAEEKTKSGIVLTGSAKEVPQEAEVVAVG PGSIVDGTKIEMEVKVGDKVLYSKYSGTEVKLDGEEYMILKQDDILAIVE" gene 17753..19375 /gene="groL" /locus_tag="groL" /db_xref="389494..391116" CDS 17753..19375 /gene="groL" /locus_tag="groL" /product="chaperonin GroL" /translation="MAKMLKFGEDARRSMQVGVDKLADTVKVTLGPKGRNVVLDKKFG SPLITNDGVSIAREIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREG LKNVTAGANPMLIRNGIRMAVDKAVEEIKKISKPVEGKEDIARVAAISAADEEIGKLI ADAMEKVGNEGVITIEESKSMGTELDVVEGMQFDRGYVSPYMSTDTEKMEAVLDNPYI LITDKKIGNIQEILPILEQIVQCGKKLLIIAEDIEGEAMATLVVNKLRGTFTCVAVKA PGFGDRRKEMLQDIAILTGGTVIAEELGRDLKEVTLDMLGQAESVKVSKDNTVVVNGK GNPENIKDRISQIKAQIEETSSEFDKEKLQERLAKLAGGVAVIKVGAATETELKERKL RIEDALAATKAAVEEGIVPGGGTAYINVINAVEKLTSDVQDTELGIKIIVKSLEEPLR QIASNAGVEGSVIIEKVKNSEVGTGYDALYGKYVNMIKSGIVDPTKVTRSALQNAASV SATFLTTEAAVAEIPQKEPAMPAPGMGMDGMY" gene 19588..19992 /gene="" /locus_tag="" /db_xref="391329..391733" CDS 19588..19992 /gene="" /locus_tag="" /product="putative pilin" /translation="LNNKFCLNNKYKKNKGFTLLELIAVMAIITILATAILPKVTGYI NEAKKTKVLDQCRKVVMAIESYNLTHSSNYEKNKNISNIKDDKSINKYLEDVEFNNLE LNTTIQNCYDILNGKEFKLKTGSEMLDLSTIN" gene 20327..21781 /gene="guaB" /locus_tag="guaB" /db_xref="392068..393522" CDS 20327..21781 /gene="guaB" /locus_tag="guaB" /product="inosine-5'-monophosphate dehydrogenase" /translation="MATIIKTAYTFDDVLLVPNKSEILPREVSVKTKLTKTISLNIPL MSAAMDTVTQSKMAIAMAREGGIGIIHKNMSIEQQAKEVDKVKRQENGIITDPIFLSK ENTLQDAENLMGQYRISGVPITENGKLVGILTNRDVTFETDFSKKISEVMTKENLITA PENTSIDEAKEILKKHKIEKLPLVDKDGNLKGLITIKDIDKAKQFPNAAKDLNGRLLC GATVGVTADMMDRVDALVKAKVDVITVDTAHGHSRGVMEAVKQIKVKHPDLQVIAGNV ATAEATEDLIKAGADCVKVGIGPGSICTTRVVAGVGVPQLTAVMDCAEVGKKYGIPVI ADGGLKYSGDIVKALAAGASVAMMGSLFAGCEEAPGEMEIYQGRSYKVYRGMGSLAAM ACGSKDRYFQDGNKKLVPEGVEGRVAYKGYVSDTIFQLMGGIKSGMGYLGSKDLDTLY ETARFVVQTASGYRESHPHDINITKEAPNYSVGQ" ORIGIN 1 atgatcaata ctcacaaact tattgcagag aatattttaa ataatacaaa cagtaagagt 61 atttatttaa tcaatgatta tagatttata tggggtaata taaaacctga ttgtgtactt 121 aaatataaaa tgataaagca ttattttatt gagagtatag atatgattat taaaaagatt 181 gaaaagttat gttctttatc gttacaagat gtttattaca aaatgtctgt aaataaattt 241 agtgaagagc ttggagttat ttgtcatttc atatgtgatt atttttgtgc tcctcattat 301 tatcgatggg aatttaagaa tacaagtcaa gtaaaaaatc atgttatgta tgaaaaggat 361 ttagctaaaa ttgccaaaga atttaattca aatggaatta taacttctaa tatagatgca 421 aataatatta aagaatttat ttatgattta caaaatcaat atgagggctc tatggatttt 481 aaaaatgatt taacatatgc ttattatgct tgtgacagta tagtaaatat ggttttaaat 541 aaagtgtttt taaatgagtg tagtttatca aaggtagtat aattagattt ttaagaaact 601 tatttttata agtttctttt ttgttgcata aatggaataa taggaatata atataaaaaa 661 acatatgaac aaataaacat atgaacatgt aaacggagga actgttatga ataatgaaac 721 taattttgta gaaagctgta aatgtaatat tatacatgaa gatacagtga ttaaggtaaa 781 agactcattg ccacaagaag aaacattgta tgatttagct gaattattta aagtgtttgg 841 agattctaca aggattaaaa taatatgtgc attatttgaa tctgaattat gcgtttgtga 901 tatggcagct cttttaggta tgactcaatc agctatatct catcaattaa gaacattaaa 961 gtcagctagg ttggttaaat tcagaaggca aggcaaagta atttattatt cattagacga 1021 tgaacatata aaacatatat ttgatgaagg atttaaacat attactgaat aagggggcgt 1081 aaattaatta tggaaaatga aattaaactt tcacttaaag gcttagattg tgctaattgt 1141 gctaataaaa ttgaaagaaa agttaatgat atggaagatg tttatgaagc tgatatgaat 1201 ttctcattag gaaaattaac agttaaattg catgaaaata aggataggga taaagtcttt 1261 aatttaatta aagatatagt taataaattg gagccagacg tgattgtaat taatgaaaaa 1321 gataatatta gttacaattt aaatactaat gaaacaaatc ataataacaa gtgtaataaa 1381 acatgctgta atcatgatag ctgttcatct cacaatcatg aaaaacatca tgtacattcc 1441 cacgataatc aggataattt tatagaaaca gaggaatgtg aaccaaatag taaaataaaa 1501 ttatttgata aaaagaaatt tttttatgaa aatcaaatat ttataatagg attaatctta 1561 tatataatag ctgttttatt taaagaaaat agctatttaa atatatctat atttgttttg 1621 agttatattt taattggtgg tgatgtatta aaaactgcat ttaataatat tttaataggt 1681 gagatttttg atgaaaactt tttgatgacc atagcaacaa taggagcatt agcaataggt 1741 gaatatccgg aagctgttgg agttatgatg ttttataaaa taggggagtt gtttcaagga 1801 tatgcagtta ataaatcaag aaaatctata acatcactta tgaatatacg tccagaatat 1861 gcaaatgtaa ttactgaata tggggagaaa agagtatctc cagaagaagt taatattgat 1921 gaattaatag ttataaaacc tggggagaga atacctcttg atggcatagt agtagaagga 1981 aaaggaagtg tagatacatc tgcattaaca ggggaatcac ttcctagaga aataaatata 2041 gatgatgaat tgttatcagg aagtataaat ttaagctcag ttataaaatt aaaggtaact 2101 aaaattttta gtgaatcaac agtatctaaa atattaaatt tagtagaaaa ttcaagtagt 2161 aaaaaagcaa aaacagagaa atttataact aaattttcaa gactatatac tccaatagta 2221 gtatttttag caatagctgt tgcgataatt cctcctatta taatttcagg agaagtattt 2281 tcagactgga tatatagggc actaatcttt ttagtaatat catgcccttg tgcattagtt 2341 atttctgtac cactaggact gtttgcaggg attggaggag catctaaaaa ggggatatta 2401 ataaagggtg gaaattatat tgaagtttta aaaaatgttg atactattgt gtttgataaa 2461 acaggaactt taacaaaagg agtatttaaa gttacagaaa ttaattctat agatatgaaa 2521 aaagaagatt ttttaagaat tgtggcttta ggtgaaagct tctctactca tccaattgct 2581 caatcaatag taaaagaatt taatgggatt ttagaaaaaa gatatgtaga aaattaccaa 2641 gaattatcag gacatggaat aaaagctata attgaaggga aaaatgttat attaggtaat 2701 tataagttac ttgaggataa taacattaat atagaaaaag tagaaaaacc aggaacggta 2761 gtatatgttg taataaacaa caagtatagt ggaaatatag taatagcaga tgaaataaaa 2821 gaagattcaa ttgaagcaat taataaattg aaaaatattg gtataaagaa gacagtaatg 2881 cttacaggag ataataaaat tgtagcaaat agtattggga aaagtatagg ggtagatgag 2941 gtgaaaagtg aacttttacc aaatgataaa gtattagaaa ttgaaaaatt aatatctagc 3001 agtacttcga aagggaaagt aatgttcgtt ggtgatggaa taaatgatgc accagttctt 3061 gcaagagcag atataggtat agctatggga gggataggat ctgatgcagc tatagaagcg 3121 gctgatgttg ttttaatgaa agataatcct acagcactag ttgatgctat aaagatagct 3181 aagaagacta atgctatatt atggcaaaat ataatttttg ctcttggtgt aaaggtgttt 3241 gtattagtat taggtgcttt aggaattgca aatatgtggg aggctgtatt tgctgatgta 3301 ggtgttactt taattgctat attaaattct atgagaagtt taaaaaatta attaaattaa 3361 aaaaatagtt atattttatt gtaaataata aaatactaat aagagcagtt tttattatag 3421 ctgctcttaa attttaaaaa aaattaaatt aatattgata tgtaaacatt tttaattttt 3481 ataaagtata attattaaat ataaacctag aaaaaaataa aattttatat tatgataaaa 3541 tatagatgat ttttatattt gcttatagtc atattaaaat aacatgattt ataggtgttt 3601 aaagggtatt ttataggtgt ttttagtaag ttattaaaat aacatttatt ttagtaatga 3661 gtatgttaaa ataatatttt atgaatattt taaagtttaa gtgtatctta tattacaata 3721 attagtaata aattagactt ttagagaaga gattaaatat aaataaaaat aaggagtaat 3781 gatatggata aaaataagaa tatatctatg gcagtgataa agagattgcc taaatatcat 3841 aggtatctta atgaacttat gaaaaatgat gtagatagaa tatcgtcaaa agaacttgga 3901 gaaaagatag gctttacagc atctcaaata agacaagatt taaattgttt tggtgatttt 3961 ggccaacaag gatatgggta taatgttaag gagttatata cacaaattaa ttcaatattg 4021 ggattagata aggaatacaa tgctgttttg attggagcag gtaatatagg tcaggcaata 4081 gctaattaca gtagattcga taagctggga attatgataa cagctatttt tgatgcaaat 4141 cctaaactta ttggaataaa aattagggat attgaaatta gagatattga cgaattagga 4201 agtttcctta aatctgattc agttgatata ggcgttatat gtgttcctaa aaaaagtgca 4261 caaaaggtta gtgatgagct agtcaatgga ggaataagag gaatttggaa ttttgcacct 4321 atagatttgg ttgttccaga agatgtaaaa gttgaaaatg ttcatttaag tgagagtgta 4381 tctacattaa tttatcaatt acatcaacaa agataaggtg agaatttgag gggttatata 4441 aaaaatatgt taataataca atattttatt gcaaataata attataagta ttataattta 4501 agaaaagaaa gatattgatt gcatattttt ttgcaagcaa ttgttaatat tataacaatt 4561 ggcgacaatt gttgacatga taagactaat gtaagccttt tatttttaaa ttcaattgtt 4621 aatattataa caattttaat tgaaaaataa attgctgaga attattttag aattaatttt 4681 taccatatct aaaatctaaa aatacaaatt tatttaagta aaaaatataa tttaaatata 4741 taagtttaag ggaggattat aaagatggaa ttaaaaaatg taattcttga aaaagaaggt 4801 catttagcaa ttgtgacaat taatagacca aaagctttaa atgcattaaa ttcagaaaca 4861 ttaacagatt tagacacagt tttagaaaat ttagaaaacg atagcaatat atatgcagtt 4921 atcttaactg gctcaggaga aaaatctttt gtagctggag ctgatatatc agaaatgaaa 4981 gatcttaatg aaaaacaagg tagagaattt ggtgaattag gaaataaagt tttcttaaga 5041 ttagaaaatt tagacaagcc tgtaattgca gctatttcag gattcgcttt aggtggcgga 5101 tgtgaattat ctatggcatg cgatataaga atagcttcag aaaaagcaaa atttggacaa 5161 ccagaagcag gtcttggaat aacacctggc tttggtggaa ctcaaagatt agctagaata 5221 gttggactag gaaaagctaa ggaaatgatt tatacatgcg atataatcaa ggcagaagag 5281 gcttatagaa taggattagt taataaagta gtttcattag aaagtttaat ggatgaagca 5341 aaagctatgg ctaacaaaat aatagcaaat gctccaatag ctgttaagct ttgtaaggat 5401 gcaataaata gaggaatgca agttgacata gacaaagctg tgttaataga agcagaagat 5461 tttggaaaat gtttttcaag tgaagaccaa acagaaggta tgactgcttt cttagaaaga 5521 agagaaaaga atttccaaaa taaataatta aaattaagtt aaaaatctaa aaaggttttt 5581 atataattga tcatcaatag agtgtaatca ataaggaggg taatttaatg aatttccaat 5641 taactagaga acaagaatta gtacaacaaa tggttagaga attcgctgaa aacgaagtaa 5701 agccaattgc tgctgaagtg gatgaaactg aaagattccc aatggaaaac gttgaaaaaa 5761 tgggtaaaat aggcatgatg ggtataccat ttgctaaaga atttggagga gcaggcggag 5821 atgttctttc atatataatg acagttgaag aattatcaaa agtatgtgca acaacaggag 5881 ttatagtttc agctcatact tcattatgtg catcagtaat aaatgaacat ggtactccag 5941 atcaaaaagc aaaatactta ccagaacttt gtcaaggtaa gaaaatcggt gctttcggtt 6001 taactgaacc gggtgctgga acagatgctg ctggacaaca aacaacagct gtattagatg 6061 gagatcatta tgtattaaac ggatcaaaaa tcttcataac taatggtgga gttgctgaaa 6121 cttttataat attcgctatg actgataaga gccaaggaac taaaggaatt tcagctttca 6181 tagttgaaaa atctttccca ggattctcaa ttggtaaatt agaagataaa atgggaatca 6241 gaggatcttc tactactgaa ctagtaatgg aagattgtat agtaccaaaa gaaaacttaa 6301 tcggtaaaga aggtaaagga tttggtatag caatgaagac tcttgatgga ggaagaattg 6361 gtatagctgc tcaagcttta ggtatcgcag aaggtgcttt tgaagaagct gttaattaca 6421 tgaaagaaag aaaacaattt agaagaccat tatcagctca acaaggttta caatggtata 6481 ttgctgaaat ggacgttaaa atagaagctg caagacattt agtatataaa gctgcttgca 6541 agaaacaaaa tggacaacca tactcagtag atgctgcaag agctaaatta tttgctgcag 6601 aagttgcaat ggatgttaca actaaagcag ttcaaatctt tggtggatat ggttacacta 6661 aagattatcc agtagaaaga atgatgagag atgctaagat aactgaaatt tatgaaggaa 6721 cttcagaagt tcaaaaaatg gttatcgcag gaagcatttt aagatagata gggaggactt 6781 tagaatgaat atagtagttt gtgtaaaaca agttccagat actacagctg taaagattga 6841 tcctaaaact ggtacattaa taagagatgg tgttccatca attatgaatc cagaagataa 6901 gcacgcttta gaaggtgcat tacaattaaa agaaacttta ggtgcaaagg taactgttat 6961 aagcatgggc cttccaatgg ctaaggctac attaagagaa gcactatgta tgggagctga 7021 cgaagctatc ctattaacag acagagcatt aggtggagca gatactttag ctacttcaaa 7081 agcattagca ggagttatag ctaaattaga ttacgatcta gtatttgcag gaagacaagc 7141 tatagatgga gatactgctc aagttggacc agaaatagct gaacatttaa atattcctca 7201 agttacttat gttcaaggcg ttgaagctaa gggcgaagga actttattag taaatagagc 7261 attagaagat ggatatgaaa agattgaaat aaagactcca tgtctattaa ctgcaattga 7321 agaattaaat gaagcaagat acatgaatgt tgctaacata ttctcaacta acgacaatga 7381 aatcaaagtt atgagcgcag atgatataga tgtagataag gctgaattag gacttaaggg 7441 ttcacctaca aaggttaaaa agtcaatgac taaagaagtt aagggagcag gcgaagtagt 7501 taacaagcca gctaaagaag cagtaactta cgttttaggc aaattacaag aaaaacacta 7561 catctaggat aataggaggg taatttatta tgaatatagc agattacaga ggcgtttggg 7621 tctttgcaga acaaagagaa ggcgaattac aaaaagtatc tttagaatta cttggcgaag 7681 gtagaaaaat tgctgataag ctaggagttg agttaacagc tttattatta ggtaataata 7741 ttgaaaactt atctaaaaca ttagcagaac atggtgcaga taaagtttta gttgcagatg 7801 acaaaaactt agaacactac actactgatg cttatacaaa agttatttgt gatttagcaa 7861 atgaaagaaa accaggaata ttatttatag gagctacttt catcggaaga gatttaggtc 7921 ctagagttgc agctagatta tcaactggat taactgctga ctgtacatca ttagatgttg 7981 aagttgaaga tggagcttta ttagctacta gaccagcatt cggtggtaac ttaatggcta 8041 caattgcttg tccagaacat agaccacaaa tggctacagt aagaccagga gttttcggta 8101 aagtaaatac tgatggaagc aactgtactg tagaaaaagt agaagttaaa cttgctgata 8161 gtgatgttag aactaaagtt gtagaaatca ttaaagcaca caaagatgtt gtagatatat 8221 cagaagctaa aatacttgtt gctggtggta gaggaatggg ttcaaaagaa aactttactt 8281 tattacaaga attagcagaa gttttagacg gaactgtagc tggatcaaga gctgctgttg 8341 ataatggttg gttagaaaga gattaccaag ttggacaaac tggtaagact gtaagaccat 8401 caatctacat tgcttgtggt atttcaggag caattcaaca cgttgctggt atgcaagaat 8461 cagatatgat tatagctatt aacaaagatg aaactgcacc aataatgcaa gttgcagatt 8521 atgctatagt tggagatgtt aagaaggttt taccagaatt aatagctcaa gctaaagctg 8581 taaagagtgc tgaataatta aaagattata gtgtaaaatt attatatatt tcaaatcctt 8641 cattaaaaga tatttctttt aatgaaggat atttataaaa catttaaggg ggatttatca 8701 atgaaaaaag tttttgtact tggtgctgga acaatgggtg ctggaatagt tcaagcattc 8761 gcacaacatg gttatgaagt aatcgtaaga gatataaaag atgaatttgt tgaaagagga 8821 atagctggaa tcaacaaagg tttaactaag caagttgcta aaggaagaat gactgaagaa 8881 gttaaagaag aaattctttc aagaatttca ggaactactg atatgaaatt agctgctgac 8941 tgcgatttag tagtagaagc tgctattgaa aacatgaaaa taaagagaga gatatttgct 9001 gaattagatg aaatctgtaa accagaaact attttagcat ctaacacttc gtctttatca 9061 atcactgaag ttgcttcagc aactaagaga gctgataaag ttattggaat gcatttcttt 9121 aacccagctc cagtaatgaa gcttgttgaa atcattagag gaatggctac ttctcaagaa 9181 actttcgatg ctataaaaga attaacagta gcaattgaaa agaacccagt agaagttgca 9241 gaagctccag gatttgttgt aaacagaata ttaattccaa tgatcaacga aggtattgga 9301 atattagcag aaggtatagc ttctgttgaa gatatagata cagctatgaa atatggtgca 9361 aatcatccaa tgggaccttt agcattagga gatcttatag gattagatgt atgtttagct 9421 atcatggatg ttttatataa tgaaacagga gacactaaat acagagctca tagtttatta 9481 agaaaatatg taagagctgg atggttagga agaaagtctg gaaaaggttt ctacgactat 9541 tcaagataaa attacatttt tggactcaag cattatgctt gggtcttttt ttatttttat 9601 taaaattttg ttttaatatg aatttttttg atttatgata tttttaagag tatattagag 9661 tgatataatg tattaagaaa taattatttt ttataaggag agtttcatat gttaaaagaa 9721 acagcaataa aatattggga tgataaatat gatttaaatt gtgcagaatg cttaatatat 9781 gcttctaatg aagaatatga tttaaactta tctaaagatg cattaaagac aatggcagct 9841 tttggcgggg gaatggctat aggcgatgtg tgtggggtga tttctggagc tatagctgta 9901 attggaatca tgtttacaga cataagtgga cataaaagtc ctattgttaa aaaaatgact 9961 acagaattta taaataaatt taaaaataag cttggaagta ataattgtat tgaattaagg 10021 aaagaatata gaaagtctaa aaaagaagga acttgtatag ttatggttga aacagcagct 10081 gatattcttg aaagtattgt aaatagagat aacaatttta aattagattc taataaatat 10141 tagtgtaaac atttatttat attgtaaaag agttatttct ttcagataaa attcttatta 10201 tattataaag atagaaaggg gaattttaat taatggatta taaaagtata gaaactagtg 10261 aaaatggtgt aattataaga ggggttaaaa attttaactt aaagcatatt tttgagtgtg 10321 gccaaatttt cagatttgaa gaaattgaag atgataattt tatagttatt gcatttggta 10381 aattgattga attagttcaa aaaaaagatg atgtatttat atataataca acggaaaaag 10441 aatttaaaga aatatggcta aactattttg atttagatag agattactct attataaaag 10501 aagaattatc taaagatgaa ttattaaaac aaagtataga atttggaagt ggagttagag 10561 ttttgaatca agatccattt gaaatgctta ttagctttat aatttcagct agaaatagta 10621 ttccatctat aagaaagaca gtaaataaaa tatctgaaca atggggaaat aaaattgaat 10681 acaaaggaaa agtatattat gcatttccta caatagaaca aataaaggat gctaaattag 10741 atgaaataaa agaaacagga gcgtcattta gaagtaagta tttaatagac acaattgaaa 10801 atgtacacaa ttctattggt aataaatcaa atttatcaga gaatgaaaaa gaattgttaa 10861 acaaatatga cttaaaatat ataaaaggat taagtgatga tgaatgccat gcagctctac 10921 aagagtttaa aggagttgga gcaaaggttg ctgattgtat aatgttattt tcaatgggaa 10981 aaacatctgc atttccagtg gatgtgtggg ttaagcgtgc aatgatgcac ttttataatg 11041 cagaagaggg ttccctaaat aaaattagag tatttgcaag aaataaattt ggaaaattat 11101 caggatttgc acaacaatat ttattttatt atgcacgaga aaacaatata aaagtataaa 11161 atttgattta tatttacaaa aacttatagt tagtaaatat tatagcaaat tcagaaaaat 11221 ttgaataata tgattatgac atctatctaa ttattattat ggtataatta ccctatcatt 11281 acattaatat aataatttgt tgggagagtg tgtgcgtaat atgttcaaat ttgaaaatca 11341 acttataaag ttaaaacatg atgttttaag taatattgta aggttagcta aagaggataa 11401 tattaataaa gaaaatttag ataaaatacc ttatgaaatg ttaccaggaa atgaacctca 11461 atatagagaa agtgtagtac atgaaagaga agtattatta gaaagattaa aattagcatc 11521 tggatttatt ccaaatggaa aaggtacaga tgagttagta aacatagaag atgaaaagca 11581 aatattgtat gttataaaaa atgcatgtga tatgtgtcca actaagaaat ttgaagtaac 11641 tgatgcgtgt agaaattgta tagcacataa atgccaaagt gtttgtaatt ttggagctat 11701 tacttatgtg gatggtaagg cttatataga tcctgataaa tgtaaagaat gtggaatgtg 11761 taaaaaagca tgtccttatg atgctattgc agaggatatg agaccttgca aaagatcttg 11821 tccaactgga gcgttagata ttaatagtga taaaagagct atgataaaac aagaaaaatg 11881 cgttaattgt ggtgcttgta tggctgcatg tcctttcgga gcattagaag atagaagtct 11941 tttagttaaa attgttaaag aattaactaa taattccaat atttatgctg ttgtggctcc 12001 agcaataaca ggacaattgg gtcctaaaac tggctatgga caagttaaaa atgcaataaa 12061 gaaattggga tttacagata tggtagaagc agcatgtggg gctgatgcag taactgtaca 12121 tgaaagtaat gaatttgttg aaagaatgga aaatggggat ccatacatga ctaattcatg 12181 ctgtccagga tttttaagtt atatagaaaa aatgatgcca gatcaagtag atagaatatc 12241 tggaacagtt tctccaatgg ttgcagcagg aagatttata aaagccaatg ataaagatgc 12301 aaaagttgtg tttattggac catgtactgc taagaagtct gaaattttaa gagattcgat 12361 aaaagatgct gttgactatg tattaacatt tgaagaatta ttagcattat ttgaaggatt 12421 taatatagat ccagctaatt tttatgatat tgttgtagat gaagcttcaa tttttggtag 12481 aggatttgga gttggtggtg gtttaactgc tgctattgaa aattatataa aagataaggg 12541 tatagattgt gaatttaaac cagttaaagt ttcaggcgga gctgagatta agaaaactat 12601 gatgatggct aagatgggta gattacctgg aaatttcata gaaggaatga tgtgtgaagg 12661 tggatgtatt aatggatcag gaaaaatatt atcaccgatg aaagcaaaat catcatttaa 12721 taaagtaaat caacaagcta ctatgaaaaa tgtattagaa aattctaaga tagatgacta 12781 taaggatata gatttagaaa gataatttta aattgcaaaa aaagaagccc ttttaggact 12841 tctttttttg taaataaatt ggtaattatg tgtggataaa aaatgaaatt acatattttt 12901 taaactaaaa tattaaaaaa tgtacattaa gtaaaaaaaa gttactatat aattattaaa 12961 aggtgtatta tataaattat aggtatgttt aggggggaga tttatgaaaa ttttgttggt 13021 tgatgatgag gaatcaatat tgaatttaat aaaaatgaat cttatatttg aaaattatga 13081 agtaataaca gcagaatgtg ggatagatgc cataaaccta tttaaaagcg aatctcctga 13141 tttaattgta ttagatctaa tgcttcctga caaagatggg tttgaggtta tacatgagtt 13201 tcaaagcata aatagtgaag ttccaattat tatacttagt gcaagagatc aattgaacaa 13261 taagttatta ggtcttcagc ttggtgctga tgattacata acaaaaccat ttgatagtag 13321 agagctcata cttagaataa gagctatatc tagaagaata aataaagcta aggctattgg 13381 aaaaaatgaa attaaaaata aaacaaacga tattatagaa aaaggattta taaaaataat 13441 tgttcctgaa agaagagtat ttattgatga caaagaagtc atatttacac atatagaatt 13501 tgaaataatc ttactaatgg tacagaatcc gtttaaagtt tttacaagag aagaattatt 13561 ggacaagata tggggatata gttttgtagg aaatactaga gctgtagata ttcatataaa 13621 gagaattaga caaaagctta taggaaatga agacgttata aagacaatat atggagtagg 13681 atataggtta gaggtataac acatgaattg gggtattaaa ggaaaaatag taataatgaa 13741 tatatttatt ttaataatag ctatattgag tatatatgtt gtaacaattt atacactgta 13801 tagtcgagta ataaataatt caatagatat gctaaggaaa gaaagttata caagtcaatc 13861 atttattatg aaatatttag aaacggaaga tgattttcat gtagaaaacg ttttgaatga 13921 gatgagtcct tttatagcaa catatttatc taataattgt aaatttagag ttcaaattta 13981 taataattca tctttaattg gagattcaga taattatcct aatataagta aggatgatga 14041 tgtagtaacg gcattgaaag gaaataaatc ttatattata agaaggattg aagaatcttc 14101 ttatatatta ttttcaagcc caatttatta ttcggatggt actataggtt gtataagata 14161 tgtatacgat cttaataacg agaatacaat tataactaat actattttaa gtatggtttt 14221 atttgctata gttgcaataa tattttcgag tatgatgagt aattcctttt ctaatagaat 14281 agttagacca atagttagtc ttaaaaatat tgcgagaaaa gtatcatttg gagatttttc 14341 taagaaaatt agtataaata gtaaagatga gatagaggat ctatctaatt cttttaatat 14401 aatgtctaat aatatagaga ttatgattga aaatttaaaa gatgaaaaag aaactcaaaa 14461 gagattttta gataatgtta ctcatgaatt taaaactcca ttagcagcaa ttttaggata 14521 ttcagattta ttgttaagag tgaaagaaaa gaaagatatt gaacaatgtg taaaatacat 14581 agtacaaagt agtaatagat tattaaaact tgttgagcaa cttcttgatt tatcgagact 14641 taacaaaaat gaattagaag ttaaaaatga aaatgtagat ataaagtcta taattgaaac 14701 tgctgcaatg atgttaaatc ctagaatgaa taaatttggt attaaactta atatgaattt 14761 aattagtaaa agtgtttatg cagataaaga aaaaacggaa caagttatac ttaatctatt 14821 agataatgca attaaatata gtgaatgtac tgaaatagac atatatatgg aaaataatga 14881 agattatgaa ataatatata ttatagataa tggacaaggc attccgaaag aagatttaaa 14941 gaatgtattt gaaaattttt atactgctca taaagcatta caaaaaaaat atggtggaag 15001 tggattaggg ttagcaatat gtaaagaatt tatggagaaa caatctggaa aaatagagat 15061 aagcagtttg aatggaacta ctgtaaaatt aagtttcaaa catgcaattt caaactgata 15121 taaagtaggg tgaaacaagt ttatgataaa ttttaactat aaaatagtga taaatctatt 15181 tgttatacta gttatattat tagctagtat atatgtatat ttaaaaagta gtatttacaa 15241 taatttgatt gttttagatg ataaagaaca agttatgcag cattcaagcc actcaatacc 15301 tgttaaagta gagctttata gtagaagatg gggtaaatta attataaatt ccaatgacga 15361 aataaaggaa ttttggaata ttgttgaggc tatgcctaag agtaataatt tttataattc 15421 aaaaatagaa aattcgttta atgagataac aggaactatt tattatttag atggtgaaaa 15481 aggtacttta tatttaaata atacacttag aatagatgat atttattatg gaggtaatga 15541 tagttcggca tatataaata gaattaaaaa ctacattaat gatatttttt gtacaccatc 15601 agtattatca gaacttataa atgataagaa taaaataaca attgtagatg tttataataa 15661 tactaaaaaa tgtggtagta atgataaagt tttaataaaa gatgaagtaa tgaatttaaa 15721 aagaattata gataataaaa agttagaatg ggctgtagcc aataaaggtg atttgaacta 15781 tcatataaga atttatagag aagaatcaga ggagtttcat gataataaaa tagaagatga 15841 ttcaaatagt tatgatgtaa taagtcttga tatttatgag aacgattatg taattgttag 15901 agattatggt gatgaaatag taaattcttt ctatatggag ggagatttaa ataatatatg 15961 tgacaattta tttaatcagt aatatttatt ggaggtaaaa atatgttaaa taaaagaagg 16021 ggtattttat taatatttgt tttacttata atttgtattc ttaatgggtg ctctagtaat 16081 atatctagtg gtaaagctag tagtaaagaa ataccaaatc ttaaaaatga gaatttagta 16141 gtttatgttg catttaatga ggatgaagcg aaggttttgc ttgatggttt taaagaaaaa 16201 acaggatgta attacacgtt tttaagatat ccaacagaag aattagctga taaaattaag 16261 agtcaagaaa ctttaggaga agcagatata tttctagggg gtacagctga tgctgttgaa 16321 ctattaaaaa tgaatgattg cttagagaaa tatactataa atagttcgag tgaaatccct 16381 atagaatata tggatagtga tggatactgg ataggattat atgttgaagc tttatcaata 16441 gcaataaatg aagatagatg ggaaaaagaa ttcaatgata ttgaaaaacc aaaaacacta 16501 gaagaactag taaaccctaa atttaaaggt gaaatagtac ttgctgatcc aaggacatca 16561 ggaactggat atactctttt atcttattta gtacaaacta tgggaaaaga tgatgcatta 16621 gaattcttta aaaagttaaa aaacaatgta gggcaattta ctgatagtgg atttactcca 16681 gctaaaaaag ttggaatggg ggaatattta ttgacagtaa attttataaa tcaacaactt 16741 atagttaaaa attcaggatt caatatagaa tctattgttc cagacaatac aggatggaca 16801 atatgtccta tagctaagat aaaggatgga aagaataaga aggcttctga agcctttatg 16861 aattactgtg taactaagga agcaggaata tctcttaaag atttttcaat gggattttca 16921 acaataccag gtgttaatta tcccaatata gaaaaagatt ttacttcata taaattaagt 16981 aaagaatatg attttaagaa agcagcaaaa gatagaaaag aattattaga agatttagaa 17041 gaaataatgt gataagaaaa ttaggatatt aaataaaatc atttatatat ttaatatcct 17101 aattttatta taacttaaat attaatgcat atattaattg ttataagtaa aaaataatta 17161 ataggctagt tttattaata aaaacataac caaacaataa aatacataaa tggaaataaa 17221 atatacaagt gtattgttaa aattaaaaaa gaaaataaga gaaaatataa gtaaatgaga 17281 gtaatatgta tgtaatatca aattttaaac ttataaagct atataatatt ataaaaaata 17341 tttgaattat atggtcataa aggatattat aataattgta ttagcactca atgctatcga 17401 gtgctaatag ttaattagaa aatatttaat atttaaaata taggagggac ttattatgag 17461 aataaaacca cttggtaata gagtagtaat caagagatta gaagcagaag aaaagacaaa 17521 gagcggtata gttttaactg gaagcgcaaa ggaagtacca caagaagcag aagttgtagc 17581 agtaggtcca ggaagtattg ttgatggtac aaaaatagaa atggaagtta aagtaggaga 17641 taaagtttta tattctaaat attctggtac tgaagtaaaa ttagatggtg aagaatacat 17701 gatattaaaa caagatgata tattagcaat agttgaatag gagagtggta taaatggcaa 17761 agatgttgaa atttggagaa gatgcaagaa gatctatgca agttggagtt gataaacttg 17821 ctgatacagt taaggtaaca ttaggaccaa agggaagaaa cgttgtttta gataagaagt 17881 ttggttcacc attaataact aatgatggag tttctattgc aagagaaata gaattagaag 17941 atccatatga aaatatgggt gctcaattag ttaaagaagt agcaactaaa actaatgatg 18001 ttgcaggaga tggtacaaca acagcaactt tattagctca agctattatt agagaaggtt 18061 taaagaatgt tactgcaggg gctaatccta tgcttattag aaatggtata agaatggctg 18121 ttgataaagc agtagaagaa attaagaaaa tttctaagcc agtagaagga aaagaagata 18181 tagcaagagt tgcagctatt tcagcagctg atgaagaaat tggtaagtta atagctgatg 18241 ctatggaaaa agtgggtaat gaaggcgtta ttactataga agaatctaaa tctatgggaa 18301 ctgagttaga tgtagttgaa ggtatgcaat ttgatagagg atatgtatca ccttatatgt 18361 ctacagatac agagaagatg gaagctgtat tagataatcc atatatttta ataactgata 18421 aaaaaatagg taatatacaa gaaatattgc ctatattaga gcaaatagtt caatgtggta 18481 agaagttatt aattatagct gaagacattg aaggtgaagc tatggcaaca ttagttgtta 18541 ataaattaag aggaacattt acttgtgtag ctgtaaaggc accaggattt ggtgatagaa 18601 gaaaagaaat gcttcaagat atagctatat taacaggtgg aacagtaatt gctgaagaat 18661 taggaagaga tttaaaagaa gttactcttg atatgcttgg tcaagcagag agtgttaaag 18721 taagtaaaga taatactgtt gttgttaatg gtaagggtaa tcctgaaaac ataaaagata 18781 gaatatcaca aataaaagct caaatagaag aaacttcttc tgaatttgat aaagaaaaat 18841 tacaagaaag attagctaag cttgctggtg gagttgctgt aatcaaagtt ggtgctgcaa 18901 ctgaaacaga gttaaaagaa agaaagctta gaatagaaga tgcgttagct gctacaaaag 18961 ctgcagttga agaaggtata gtaccaggtg gtggaactgc atatattaat gtaataaatg 19021 cagttgaaaa attaacatct gatgttcaag atacagaact tggtataaaa ataattgtaa 19081 aatcattaga agagccatta agacaaatag ctagtaatgc tggcgttgaa ggatctgtta 19141 ttatagaaaa agttaaaaat agtgaagtag gaacaggata tgatgcttta tatggaaaat 19201 atgtaaacat gataaagagt ggtattgttg acccaactaa ggttacaaga tcagctttac 19261 aaaatgcagc atcagtatca gcaacgttct taacaacaga agctgcggtt gctgaaattc 19321 ctcaaaaaga accagcaatg ccagcaccag gaatgggaat ggatgggatg tattaataaa 19381 taaaaaagac taccagttgg tagtcttttt tatgctttat aaaaatatat aactttttaa 19441 gcttgaaagg ctgttaaaat ttagtttaag ataattactt taaaataagt aattttatta 19501 taaatatata ttaacaatat ttgtatatta actgacttag atagcaataa ttaaaataat 19561 aatattttaa ttattggagg ataatatttt gaataacaaa ttttgtttaa ataataagta 19621 taaaaaaaat aaaggattta ctttattaga acttatagca gtgatggcga ttataacaat 19681 attagcaact gctattttac ctaaagtaac tggatatata aatgaagcaa aaaaaacaaa 19741 agtattagat caatgtagaa aagttgtaat ggcaatagaa tcttataatt taacacattc 19801 ttctaattat gaaaaaaata aaaatatatc taatataaaa gatgataaaa gtataaataa 19861 atatttggaa gatgttgaat ttaataattt ggagttaaat acaactattc aaaactgtta 19921 tgatatatta aatggaaaag aattcaaatt gaaaacaggc agtgaaatgc ttgatttatc 19981 tacaattaat tagtgaaatc gattaaatta aatagatttg taatttttgc aattttaatt 20041 tcaattttat tgactttgat catagcatac attataatat ttttaattaa acaaagaaaa 20101 tatttaaaaa ctcgtatata ccttgaatat ggcaaggagt atctaccaga aaccttaaat 20161 ttctgactat gagtgatatt aatactttag tatatttgag atatattaac gtattaactt 20221 cacttacgga gttaatgcgt ttttttttat acataaaaat ataagaaaaa tgcaagataa 20281 cattcaaaaa agtgaaaata tgaaataaaa aaatcggggg gataattatg gctacaataa 20341 taaaaacagc ttatacattt gatgatgtat tattagtacc taataaatca gaaatattac 20401 ctagggaggt aagtgtaaaa acaaaattaa ctaaaacaat atctttaaat atacctttaa 20461 tgagtgctgc gatggataca gtaacacaat ctaaaatggc tatagctatg gcaagagaag 20521 gtggaatcgg aattatccat aaaaatatga gtatagaaca gcaagcaaaa gaagtagata 20581 aggtaaaaag acaagaaaac ggaattataa ctgatccaat atttttatca aaagaaaata 20641 cacttcaaga tgctgaaaac ttaatgggtc aatacagaat atctggtgta cctataactg 20701 aaaatggcaa attagtaggt atacttacaa atagagatgt aacttttgaa acagatttta 20761 gtaaaaaaat atctgaagtt atgacaaaag aaaatttaat tactgctcca gaaaatactt 20821 ctattgatga agcgaaggaa attttaaaga agcataaaat agaaaagtta cctttagttg 20881 ataaagacgg aaatttaaaa ggattaatta caattaagga tattgataag gcaaaacaat 20941 ttcctaatgc tgcaaaagat ttaaacggca gattattatg tggggctact gttggtgtta 21001 cagctgatat gatggataga gttgatgcat tagtaaaagc taaagttgat gttattacag 21061 tagatactgc tcatggtcat tcaagaggag ttatggaagc tgttaaacaa ataaaagtta 21121 aacatccaga tctacaagtc atagctggta atgttgcaac tgcagaagca acagaagatt 21181 taataaaagc tggagctgat tgtgttaaag ttggtatagg accaggatca atatgtacta 21241 caagagtagt tgcaggtgtt ggagtaccac aattaactgc tgttatggat tgcgcagaag 21301 ttggtaaaaa atatggaatt ccagtaattg cagatggtgg attaaagtat tcaggagata 21361 tagtaaaggc tttagcagca ggagcatctg tagcaatgat gggatcatta tttgcaggtt 21421 gtgaagaagc accaggagaa atggaaatat accaaggtag aagttataaa gtatatagag 21481 gaatgggttc attagcagct atggcttgtg gatcaaagga cagatatttc caagatggaa 21541 ataaaaaatt agtaccagaa ggtgttgaag gtagagtagc atataagggg tatgtttcag 21601 atactatatt ccaattaatg ggcggaataa aatcaggaat gggatactta ggttcaaaag 21661 atttagatac tttatatgaa actgctagat ttgttgttca aacagcatca ggatatagag 21721 aaagtcatcc acatgatata aacataacta aggaagctcc aaattatagt gtaggacaat 21781 aa //