LOCUS NC_010718:23 19079 bp DNA linear BCT 25-AUG-2011 DEFINITION Natranaerobius thermophilus JW/NM-WN-LF, complete genome. ACCESSION NC_010718 SOURCE Natranaerobius thermophilus JW/NM-WN-LF, complete genome. COMMENT locus start: 2977021; locus end: 2996099 FEATURES Location/Qualifiers source 1..19079 /organism="Natranaerobius thermophilus JW/NM-WN-LF, complete genome." gene complement(0..920) /gene="" /locus_tag="" /db_xref="2977021..2977941" CDS complement(0..920) /gene="" /locus_tag="" /product="binding-protein-dependent transport systems inner membrane component" /translation="VHIYIIKRLLQAIPVLFIVTIITFSLVHIMPGDPALIMAGEDAD PETVERMREAMGLHRPIHEQYLDWLSGVLQGDLGTSLRDHRPVLPSILQRLPATLHLV LASFVVSFSIGIPIGILSAVKQNTVIDSIARVFALLGISLPNFWLGLMLMFIFSHRLQ LLPASGSGTIWHLIMPAIALGTASAGLITRLTRSSMLEVIRQDYVRTARSKGLGEKAI IYKHALKNAMLPVVTIVGLQLAARLGGSVIVETVFAYPGMGRFAFERMMARDMPMIMG ILFVFAVIFIVINLITDICYGFLDPRIRYD" gene complement(1099..2673) /gene="" /locus_tag="" /db_xref="2978120..2979694" CDS complement(1099..2673) /gene="" /locus_tag="" /product="extracellular solute-binding protein family 5" /translation="LFRKRLLTILTCILIFSLTIVTACSSDEEAGDTGPAESTDELVW GITEEADTLDPRATVSTYSVEVFEMVFNSLVYPDGDLEIQKDLATDIEVKDDDVTYVF ELRDDVTWHDGEPLTAHDVEFTYETILDPEFGSPHKERIDYIKRVEAIDDYTVEFETE DPHAAFLHDLDRFIVPKHAAPRNPFEDVDEVEEEKEGEDVFAYEPIGSGPFKVVEWRP NDTLTLERYEDYHEGPAELKKIIRREIPEVEAIYADLMAGDIDKGIVPDQEIDDIDEN PDYTLIQERTLNYFPIFINHGYDGHDKLSQLEVRRALNKAADYDQIVEHIFPTSYRAH TPIIEGTWAHDPDAVRVYEHDPEKARELLEEAGYEEGIELELIMSDSNTNMEFGEMLS AQFEEAGIDLDVNTMDFGAMLDRTLDGDYQLSSVGMTNMTDPDEFMQRYVDGGGASNY ENPEMDELIIEARRTVDDQEKRAELYSEIQEIFSEEAVDIPIRNSTILVVWNSDFNMD YNYIERYRNMKDAYWD" gene 3232..4233 /gene="" /locus_tag="" /db_xref="2980253..2981254" CDS 3232..4233 /gene="" /locus_tag="" /product="agmatinase" /translation="MSRRSLWRGLYRKDFSPGEADFTILGIPFDKGCSFREGTCSGPE YIRSSSDRNPPVTEDGAQLTASVCDMGNIPFQDVFETQRDYFEKVQDQVEEIFKAKYL QNDHMFPIFLGGDHSITIPLLRAIDQVYKGDEEDIAIIHFDTHLDICDTLDENPLSHG STHRRGWELDVFKPEHTYFVGIRCSEAQEHNFLHGKQTNIVTAKQIFMEGPLKMAQQI ADLVGNRKTYLTLDIDVLDPAFAPGTGTPVAGGLSSRELLIMLEELSKLNLIGMDLVE VSPPWDNSEITLYSAQKIIFEMMGYMAPKDKKGDSILNQFSLKQTGSFNYQYYDSQA" gene complement(4202..4789) /gene="" /locus_tag="" /db_xref="2981223..2981810" CDS complement(4202..4789) /gene="" /locus_tag="" /product="orotate phosphoribosyltransferase" /translation="MTKDNRIMEIFEQTGAITHGHFLLTSGRHSDCYVQCAQVLQYPY YTEQLVQELGKKLPGDYDMIVGPAMGGVILSYEMARYYNVKAVFSERQKGKMTFRRGF EISPGQKVLVVEDVVTTGGSVQEVIDLVNEKGAIVSNVAALVDRSGGNISFSGVENGF VSLIEMNIKSYEEQDCPLCEQGSTPVKPGSRNIDS" gene complement(4782..5615) /gene="" /locus_tag="" /db_xref="2981803..2982636" CDS complement(4782..5615) /gene="" /locus_tag="" /product="orotidine 5'-phosphate decarboxylase" /translation="MEIEISTESGGIWYMKDKGDNNRNDQPAREKSTDLEDKLIVALD MPDRTQALSLVDELGEQIKWYKIGLELFCSQGPEIISELVDRDKKVFLDLKLHDIPNT VSRTAKELVRRGASMINVHTAGGKDMMARTVEEVHTEASGRGITPPKIVGVTVLTSLG QNEFNNQLGFNGHIEDKVVEWAQMARNSGLDGVVASAKEAAQIKEKLGAEFLIVTPGI RLASDDKSDQKRVLTPDKALNKGATHIVVGRSITGKEGPGQKKTAVQEIYNCMRSEQN D" gene complement(5606..6517) /gene="" /locus_tag="" /db_xref="2982627..2983538" CDS complement(5606..6517) /gene="" /locus_tag="" /product="dihydroorotate oxidase B, catalytic subunit" /translation="MADLKVNFAGIPMKNPVASASGTFGFGFEYQSVISPHELGALVV KGLTLSPKRGNQGTRLHETASGLLNSIGLENPGIDNFINEILPDLRQCDATTLINISG GNDEEYVEITQKLNNCQGIAGLEVNISCPNIREGGLVYGVDPELTYRLVSKVRQSTSF PVIVKLSPNVTDITEIAKACERAGADGLSLINTVAGMAIDIDQKEPVFDNISAGLSGP AIKPIALKAVYQVSQAVDLPVMGMGGIYNYQDAIEFILAGATSVALGTVNFAEPTAAK SIIQGIDNYLEREGYLSVNDIRGLAWK" gene complement(6510..7337) /gene="" /locus_tag="" /db_xref="2983531..2984358" CDS complement(6510..7337) /gene="" /locus_tag="" /product="oxidoreductase FAD/NAD(P)-binding domain protein" /translation="MWYDELGKISYHTKIAPQIFLMKIKLPKISTSIHPGQFVNIQVN GAYDQKEDSFATIISDPLLRRPISVYDVCPQEGELSIMYQVVGRGTQILSSQAEGTRL KVMGPLGNGFSLDEGQKVALVSGGIGIAPLYLLSKKLASNNCQPHLLAGFSGEEQVRL LQDFHELNNMNIKLATDDGSAGYHGQVTDLLKNFLSSYQEQIDMVVTCGPEIMMKKVV DLATRANLPVKLSVERKMACGVGACLGCTCESVDNQSYKHACIDGPVFWGNEVKLNG" gene complement(7327..8652) /gene="" /locus_tag="" /db_xref="2984348..2985673" CDS complement(7327..8652) /gene="" /locus_tag="" /product="dihydroorotase, multifunctional complex type" /translation="MGILLKGGIIYTGEPVSDGTQMDILIEDGMIKDQQRNINPEELG KSESEQLEIIDVSGLTIVPGLVDMHVHLREPGFEYKETIATGTKSAARGGFTSIACMP NTKPTADNSGTIEFIKQRAKEQGLVHTYPIAALTVDRVGKEIVEMDDLYSAGAVAFSD DGSWVHDSGVMRTALEYSQLFNVPVISHCEDEGLSDSGQVNEGYLASVMGLSGIPNES ESIAVARDVMLSELTGAHLHIAHISTAQSVDIIRKAKDRGVPVTAEVTPHHLILTDST IQNYNTMAKVNPPLRTEEDVKALRQGIKEGVIDCIATDHAPHSTDEKNVEFDNAPFGL VGLETAFSVSKKALVDSGVLSLSELIEKMSTNPAKLLKLPSGKLVHEAPADLTILSLD EKYTVNPGDFASLGKNSPFAGWELEGKIVATMVSGEFSYRQFGSDDHVV" gene complement(8636..9577) /gene="" /locus_tag="" /db_xref="2985657..2986598" CDS complement(8636..9577) /gene="" /locus_tag="" /product="aspartate carbamoyltransferase" /translation="LGLQRKSLLGLKDMEKSEIESILDSTESMKEIVQRKNKKLPTLK GFSMVNLFYEPSTRTRSSFEMAGKYLGADTTNMSASASSVAKGENLIDTGKTLEAMGI NLIVMRHPLAGAPRLLANNLSCSIINAGDGYHEHPTQALLDMFTIKEYKGSLKGLKVT IIGDIYHSRVARSNIWGLTKMGADVRLAGPPTLLDQRVFTEMGASCYYRVEDALADAD VVMALRIQRERQGKTLLPSLREYARLYGINQERFKLAKKDALLLHPGPVNRGIELTSE LMNSEKSVIEEQVTNGVAIRMALLYHLSGGEDNGDIA" gene complement(9806..10354) /gene="" /locus_tag="" /db_xref="2986827..2987375" CDS complement(9806..10354) /gene="" /locus_tag="" /product="Uracil phosphoribosyltransferase" /translation="VVQEKAEIMDQEKFNRTLTRISHEIIEKNKGIDDLVLIGIRTRG VPLAERLAHKIEEIEGESIATGLLDITLYRDDLSTLSEKPILNKTEVPFSIKNKKVVL VDDVLYTGRTARAALDAVIDLGRPKYIQLAVIVDRGHRELPIRADYVGKNVPTSKKEL ISVRLSEIDGEDRVMIEETVKE" gene 10841..12193 /gene="" /locus_tag="" /db_xref="2987862..2989214" CDS 10841..12193 /gene="" /locus_tag="" /product="amino acid carrier protein" /translation="MEFLLTINDALNEIVWGPPFLILLVGTGLYLTIRLRFFQFTHFG TSWKETIIERIKKTESGEAGAITGFQAITSAMAATIGIGNIAGVATALHLGGPGALFW MWITALVGMATKFGEAALGVKYRTDEDGEISGGVMYYIQNGLGKNWMWLAILYALFAG IAAFGIGNMVQSNTVAEAVADDFGVPMYITGLVAAVLVALVILGGIKRIAQVAEILVP IMTVVYILGALVIILMHLPEVPGAFRDIFVHALNPGAAGGGAAGAGIMVAIRYGVARG IFSNEAGLGAASIVHAQARNTPAKQGMWGIWEVFIDTILVGTMTALAILVTGALESGE TGAVLTSEAFNRGLPGPGGVFITIAIMVFAYTTMLTWSFYGEKSWEYIFGPKIRIPYR IIFLILIFTGAVGALEVVWDFADTMNGLMAAPNLIALIALGGVLAKEKDKYINNELDK" gene complement(12368..13633) /gene="" /locus_tag="" /db_xref="2989389..2990654" CDS complement(12368..13633) /gene="" /locus_tag="" /product="major facilitator superfamily MFS_1" /translation="MKLTANFSLKNYRRVVWGVLALAYLLGFFHRYSLGVVADTLREE LALSGTALSNLASIYFYSYALMQIPSGILADTVGPRKVATIGFLLASSGSVLMGISQE IALLYLGRFLVGIGVAGLLICIFKIQSVWYRPEEFATMTGWSALMGNSGALFATTPFA VMVLNLGWQNSFILIGLFSFIILGLIWTFVRDDPQDLDYPPINRHHSTQSFKTINLSK GFKSVLSNSNTWFCFVILMGLHGAMMSFSGVWGVTYLQSSYEIAKDQAASLIFVFTLG VIVGSPVMGKLSDRLGNRKLLIQISAAVFLIFWLYKLVLWQGTPPTIHLPFLYFMGGF FAIFAMLCQAVGKESNDPSYTGIAVSVINTAPFIGTTVMNFFIGIVLDITGHTGVYGY RLGFLIYAVFSLIALICAYFLKEKSVHSS" gene complement(13617..14840) /gene="" /locus_tag="" /db_xref="2990638..2991861" CDS complement(13617..14840) /gene="" /locus_tag="" /product="N-acetylglucosamine-6-phosphate deacetylase" /translation="MALILRNAQLITEQGVLSPGYLIAGNDGYIWDLGRDVDDNVLAP SDTSIDQGELGLIESKEIDLQGKYLAPGFIDLHTHGGLGFDIMDADTKGLEKISAFYL KQGVTGFLATTFSSSWSEIKQAVGTVRKYLDNKASNQIDTNLLGMHLEGPFINPEKKG VQTEKNIIPPSLKSVNELWELAGAHLYMISLAPEMKNASQLIKWGRRHNIIMSAAHTD ATYEEMNNAFSAGLSHGAHLFNGMSAIHHRAPGAAIALLLHPEATIELIVDGKHLHPA ILDLVIKQKPLDKIVLVTDSIRGTGLEEGKFQLDKQIVTVKNNTAKTQEGQLAGSTLT IPEALKNIMKFTSLSLTEAVKMISLTPAKILGLSQERGSLLPGKRADAAVLTEKLEVK NTILKGKLINNEINS" gene 15220..15852 /gene="" /locus_tag="" /db_xref="2992241..2992873" CDS 15220..15852 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MVQIAGSAESEFADAAKQGLTPEVDFYIGRNIILFGYHIHHFYF GILLLAIAGWIAIVGSKHFSREHAALCYGAGLGLFMDEIGLLLTWGDYYSSLTYLLSL FLAGILLNIVFFPYFWKDVKNNLIASRPDSSFWNRAFKNHKVIEVVDNMSEKTEQSTK ASLVFSGIVYIAMGGLILIFPEFVYYWIAGGFFLQGIASFVNAWQQKESN" gene complement(16041..17282) /gene="" /locus_tag="" /db_xref="2993062..2994303" CDS complement(16041..17282) /gene="" /locus_tag="" /product="amidohydrolase" /translation="MKDTTKNIIFENVKLFDGEKIIENATIVIKDGLIADVLDKDEAI QDDQAEFTGQVYNLKGRTLLPGFIDAHTHLDLHGMADTYDENLVEDKLRAIRAAKEME TTLQAGFTTIRNLGSVNGIDISVKAAVEQGIINGPRILTSGKILCITAPGSEYFNGLY EEVNGYDAFKEAAREQLKLGADVLKIMATGAIMNPGGVAGAVQPDVDEIKAVVEEGDK LNKKVASHAHGAEGIKNSIKAGVHTIEHGTFADEEALEMMLQHNIYYVPTLAPDYFMT EYGKEGGVAPFMVEKLKHKKEARIKTLRKAVEMGIKVASGSDAGTPYNFQGNNAREMA LMVEYGIMSSQEALKTGTKIAAKACGLEGEVGQIKQGMEADLIVIDGNPVEEINLITD TKNIQLIMKSGKIVKDVLSRS" gene complement(17416..18156) /gene="" /locus_tag="" /db_xref="2994437..2995177" CDS complement(17416..18156) /gene="" /locus_tag="" /product="glucosamine-6-phosphate isomerase" /translation="MKLTVVDNYFQLSQKAAEIITDQIISKPNTILGLPTGRTPLGMY ESLISRYQQGQLTFKDVTTFNIDEFLGISEDNPISYHSYMNYYFFDHIDIDKENTFLP PSNPEDPIIAAANYEQKVKENPVDLMILGLGTNGHIGFNEPGNSLREDTHVTELSDQT IINNKKLLKKTLGNESKDDYAIPDKAITMGIGTILSAQKLLIIANGSEKAPVIKQLFS PEITTRLPASLVKLHSNVTIIVDGEAYN" gene complement(18214..18699) /gene="" /locus_tag="" /db_xref="2995235..2995720" CDS complement(18214..18699) /gene="" /locus_tag="" /product="PTS system, glucose subfamily, IIA subunit" /translation="VVASSKWTEIKAPFSGKVVDLNEVEDPKFAQGEAGKGAAITPSE ETDGILVSPVKGKITKTFDTNHGIGLATEDGLEILINIGSETVQLEGYGFEGLVEEGE QVDESQPLIKFDHQIIKQAGKSLVTPVVITDSNRIEEVEYNSGNETEAGDVLFKAKIT G" ORIGIN 1 ttagtcatat cttatccttg gatctaaaaa tccgtagcag atatcagtta tcaagttaat 61 cactatgaat attactgcaa atacaaacag aatccccatg atcataggca tgtctcttgc 121 catcatgcgt tcaaaagcaa atctccccat tccgggatag gcgaaaaccg tttcaacaat 181 caccgaacca ccgagtctag cagctaactg taaaccaact atagtcacaa ctggtagcat 241 agcgtttttc aaagcatgtt tatatataat tgctttttct cccaaccctt tagatctggc 301 agttctaaca taatcctgtc taataacttc taacatactg gaacgcgtca atcgggtaat 361 caaacctgca gaggctgttc ccaaggcaat ggcaggcata attaaatgcc aaatcgtccc 421 actaccactg gctggtagca attgtaatct atgtgaaaat ataaacataa gcatcaatcc 481 cagccaaaag ttaggtaagg aaattcccaa aagagcaaac acccgagcaa tggaatcaat 541 aactgtattt tgcttgactg ccgacaaaat tccaatggga attccaattg aaaaagatac 601 tacaaaggat gccaatacaa ggtgaagagt cgcaggaagc ctttgcagaa tcgacggtaa 661 aactggtcga tgatcacgta aggaggtacc aaggtcaccc tgtaatactc cactcagcca 721 gtccaagtac tgttcatgaa ttggcctgtg aagacccata gcttcgcgca ttctttccac 781 cgtttcggga tcagcatctt ctcccgccat aattagcgct ggatcgccag gcatgatgtg 841 taccagtgaa aatgttatta tagttacgat aaaaagtacc ggaattgctt gaagcaatct 901 ttttattata taaatgtgca cgaacctacc tccttccaat attacaacga atattattta 961 ggaatatact tgtatttgga actaccatgt atttaggggc gggggagtta agccccgccc 1021 ctaattggga actggtaata cctacaagtt ttattttgta taactcattt gtcttagata 1081 tcaggtctca taattattct taatcccagt aagcatcctt catattacga tatcgctcaa 1141 tatagttgta gtccatatta aaatcagaat tccaaactac aagtattgta ctatttctga 1201 tgggaatatc aaccgcctct tcactaaaaa tctcttgaat ttctgagtac agttctgctc 1261 ttttttcttg atcatccacg gtccttctag cttctataat caactcatcc atttcgggat 1321 tttcataatt ggaagcccca cctccatcta catatcgctg cataaattca tcaggatctg 1381 tcatattagt catcccaact gaactaagct gataatcacc atcaagagta cggtccaaca 1441 tggcaccaaa gtccatggta ttgacatcta agtcaatgcc ggcttcttca aattgtgcac 1501 ttaacatttc accaaactcc atattggtgt tagaatcact catgatcaat tctaattcaa 1561 taccctcttc gtaacctgct tcttctagta gttctctagc tttctctggg tcatgttcat 1621 aaactcgaac tgcatcaggg tcatgggccc aagtcccttc tatgatggga gtatgagccc 1681 tgtatgaagt agggaaaatg tgttcaacta tttgatcgta atcagcagcc ttatttaatg 1741 cacgacgcac ttctaattgg cttaatttat catgaccgtc gtagccgtga ttgataaaaa 1801 tcggaaagta atttaaggtt cgttcctgta tcaaagtata atcgggattt tcatcaatat 1861 catcaatttc ttggtcaggc actatccctt tatcaatatc accagccatt aagtccgcat 1921 atatcgcttc cacttctggt atttcgcgtc taataatctt cttcagttca gccgggcctt 1981 catgataatc ctcataccgt tctaaggtca gtgtatcatt aggtctccat tcaactactt 2041 taaaaggacc tgaaccgata ggttcatagg caaaaacgtc ttctccctct ttttcttctt 2101 ctacttcatc cacatcctca aaagggtttc taggagctgc atgttttgga acaatgaatc 2161 tatctagatc gtgtaaaaaa gcagcatggg ggtcttcagt ttcaaattca acggtataat 2221 catctattgc ttctaccctc ttaatgtaat caattcgctc tttatgaggt gatccaaatt 2281 ctggatctaa aatggtttca taggtaaact ccacatcatg agcagttaaa ggttctccgt 2341 catgccatgt gacatcgtct cttaattcaa aaacataagt gacatcgtca tccttgactt 2401 caatatcagt tgccagatct ttttggattt ccaaatcacc atctgggtaa accagtgaat 2461 taaaaaccat ttcaaaaact tctacagaat atgtagaaac tgtagctcta gggtcaaggg 2521 tatcggcttc ttcagtaatt ccccaaacca gttcatcagt ggattcagca ggaccagtgt 2581 cgcccgcttc ttcatcagat gagcaagcag tgacaatggt tagggaaaag attagtatac 2641 aagttaatat tgtcaacaac ctttttctaa acaaattcat tccccctcga aaatatttta 2701 tttgggtttt gtattgcgga taatttactt tataatagta catattttta ttgatggacc 2761 acctccaggt cacacagtcg ttacccagtc gaactacttt ctttatttca attccactct 2821 agctattccc ttttttggac gctatctttt ggaattccaa ttttctgcaa tttttgattt 2881 tgtttccttt tgaaacaagg tttaaccaag ggatgatagt acattatttg ctttcagaca 2941 gtgttccctt tatttttcta taaaaaattc ttatttcctg ttagtattaa aaaattattt 3001 cactatgtaa caaagatgta aggtgatact aagtatagat cttagaaatt ttgatatctt 3061 taacaaaatt aactttaata aaaattaaca gttaaaatct ctaaagcagg aataatcaag 3121 taggtcgcga aatttataac ttgttaagct ataatcaaac tagcacacaa atccttgtcc 3181 tagatttgga caaggataat actacaacta tacaagtaga ggtgatcagt aaatgagtcg 3241 aagaagtttg tggcgaggtt tatatcgcaa agacttttct ccaggtgaag ccgattttac 3301 aattttaggt attccctttg ataaaggttg tagttttagg gaaggtacgt gctccgggcc 3361 tgagtacatc cgctcaagtt cagatcggaa tcctcctgtt acagaagatg gggcacaatt 3421 aactgccagt gtttgtgata tgggaaatat cccttttcaa gatgtcttcg aaactcaaag 3481 agattatttt gaaaaagtac aagaccaagt tgaagaaatt ttcaaggcca agtatctcca 3541 aaatgatcac atgttcccaa ttttcttggg cggagatcac tcaataacca tacctttgtt 3601 aagagctata gatcaggtct ataaaggtga cgaagaagat atcgccatta ttcactttga 3661 cactcatctc gatatatgtg acacattgga cgaaaatccc ctttcccatg gcagtaccca 3721 taggaggggc tgggagttag atgttttcaa gccggaacac acttattttg tcggaatcag 3781 atgttcagaa gcccaagaac ataatttcct ccatggaaaa cagactaata tagtcacagc 3841 aaagcagatc tttatggagg gccctcttaa aatggctcaa caaatcgctg atttagttgg 3901 aaatcgcaaa acttatttaa ctttggatat cgatgtctta gatccagctt ttgctccagg 3961 aacgggcact cctgtggcag gagggctaag cagccgggaa ctgttaataa tgctagaaga 4021 attatctaaa ctaaatttga ttggcatgga cttggtagag gtatctccac cttgggataa 4081 ttctgaaatc actctttact cggctcaaaa aattattttc gaaatgatgg gatacatggc 4141 accaaaagat aaaaagggtg actccatctt aaatcagttt tccttaaaac aaaccggttc 4201 ttttaactat caatattacg actcccaggc ttaacaggtg tgctcccctg ttcacacagg 4261 ggacaatcct gttcttcata ggatttgata ttcatttcta ttagggaaac aaatccattt 4321 tcaacccctg aaaaacttat attcccacca cttctatcca caagggcagc cacattgctg 4381 actattgcac ctttttcatt aacaagatca ataacttctt gaacagaacc tccagttgta 4441 accacatcct cgacaactaa aactttttgt ccgggagata tttcaaagcc cctacgaaaa 4501 gtcattttcc ctttctgccg ttcggaaaat actgctttca cattgtagta tcttgccatt 4561 tcataggaga gaatcacacc tcccatggct ggtcctacga tcatatcata gtcccctggc 4621 aactttttac ccagttcctg aactaactgt tcagtataat acggatattg aagaacctgg 4681 gcacattgaa cataacaatc actgtgtctg cctgatgtta ataagaaatg tccatgagtt 4741 attgcacctg tttgttcaaa aatttccata atacgattat ctttagtcat tttgctcact 4801 cctcatacag ttatatatct cttgaaccgc tgttttcttt tgccctggcc cttctttgcc 4861 agtaattgat cgtcctacca ctatatgggt agcaccttta tttaaagcct tatctggagt 4921 caacacccgt ttttggtcac ttttatcatc agaagccaac cgaattcccg gtgtaactat 4981 taaaaactct gctcccaact tttctttgat ctgggctgct tctttagctg aagctaccac 5041 tccatctaac ccactatttc gggccatttg agcccattcg acaactttat cttctatgtg 5101 accattaaac cccaattgat tattaaattc attctgtccc aaactagtca ataccgtcac 5161 accaactatt ttaggtggtg tgattcctct accacttgcc tctgtgtgta cctcttccac 5221 agttctagcc atcatgtcct taccgcccgc tgtatgaaca tttatcatag atgcgcctct 5281 tcgtactaat tctttagctg ttctggaaac agtattggga atatcgtgaa gttttaaatc 5341 caaaaatact tttttatctc tatccaccaa ttcagatatg atttctggtc cctgggaaca 5401 aaataactct aaaccgattt tataccactt aatttgttct cccaactcat caaccaggga 5461 aagggcttgt gttcggtcag gcatatccag ggctacaatc aatttatcct ctaggtcagt 5521 tgacttttcc cttgctggct gatcatttcg attattatct cctttatcct tcatatacca 5581 gatccctcca gattcagtac tgatttctat ttccatgcca aacctctgat atcatttact 5641 gaaagatacc cttctcgctc caagtagttg tcaatcccct gaattattga tttggcggct 5701 gtaggttcag caaaattaac cgttcccaaa gctactgaag tcgcgccagc caggataaat 5761 tcaatggcat cctggtaatt ataaattcca cccatgccca tcaccggtaa gtcaactgct 5821 tggctcacct ggtaaactgc ttttaaggca ataggtttaa tggctgggcc agataggccg 5881 gccgaaatat tatcaaaaac aggctctttt tggtcaatgt caatagccat acctgcaaca 5941 gtatttatga gagaaaggcc gtcggcaccc gctcgttcac aagctttggc tatttcagtt 6001 atatctgtga cattggggga taatttcaca ataactggaa aggaagtgga ttgccgaact 6061 ttagaaacca agcgatatgt cagttcggga tctaccccgt ataccaatcc cccttctcgg 6121 atattaggac acgaaatatt aacttccaag cccgctatcc cttggcaatt attgagcttt 6181 tgtgtaattt ctacatattc ttcgtcgtta ccacctgaaa tgttaattaa ggtagtagca 6241 tcacattgac gtaaatcagg taatatttca ttaataaagt tgtcaatgcc gggattttcc 6301 agaccaatgg aattcaacaa gcccgaagct gtttcgtgca gcctggttcc ttgattaccc 6361 cttttgggag acaaagttaa tcccttaact actaaagcac caagctcgtg tggacttatg 6421 accgattgat attcaaaacc aaatccaaaa gttcccgatg ccgatgctac aggatttttc 6481 attggtattc ctgcaaaatt caccttaaga tcagccattt agtttcacct catttcccca 6541 gaagacagga ccatcgatgc atgcatgctt gtaggattga ttatccacag attcacaggt 6601 gcaaccaaga caggcaccaa ctccacaggc catttttcgt tctacagata attttacagg 6661 tagattagct cgagtagcta aatctacaac ttttttcatc attatttctg gcccacaagt 6721 aaccaccata tctatttgtt cctgatagct tgacaaaaaa tttttcaata gatcagttac 6781 ctgcccatgg tagcccgcag acccgtcatc agttgccagt ttgatgttca tattattcaa 6841 ttcatgaaaa tcttgcagta acctgacttg ctcttcccct gaaaaacctg ctagaaggtg 6901 gggctgacaa ttattagaag caagtttttt actcagcagg tataagggtg caatgccaat 6961 ccctcctgaa actaatgcaa ctttctgccc ttcatctaac gaaaagccgt ttcctaaagg 7021 acccataact tttagtcttg ttccttcggc ctgagatgac aaaatttgcg ttccacggcc 7081 gacaacctga tacatgatag atagttcccc ctcttgggga cacacatcgt aaacgcttat 7141 gggccttctg agcaggggat cacttataat tgtcgcaaag ctgtcttcct tctgatcata 7201 agctccattg acttggatgt tgacaaactg ccccggatga atactagtgc taatttttgg 7261 aagctttatc ttcattaaaa aaatttgtgg ggcaatctta gtgtgatagc ttatttttcc 7321 taattcatca taccacatgg tcatcgctcc caaattgtcg ataactaaat tcccctgaaa 7381 ccattgtagc gacgatttta ccttccaact cccatccagc aaaggggctg tttttgccca 7441 gggaagcgaa gtcgcctgga tttacggtat atttttcatc taatgacaaa atggtcaaat 7501 cagctggggc ttcatgtact aactttccac taggaagttt taacagctta gcaggatttg 7561 tggacatttt ttcaattagt tctgaaagtg acaacacacc actgtccact agagcttttt 7621 tggacacgga aaaggctgtt tccaaaccaa ctaatccaaa gggggcattg tcaaattcca 7681 catttttttc gtctgtactg tggggggcat ggtcagtggc tatacagtcg atcactcctt 7741 cttttatacc ctggcgtagg gccttaacat cttcttctgt tctgagagga gggtttacct 7801 tggccattgt attgtaattt tggattgttg aatcagttaa tattagatga tgaggagtaa 7861 cttctgcggt tacaggtact cctctatctt tcgcctttct aattatatca acggactggg 7921 cggtactgat atgagctatg tgaagatgag cacctgttaa ctcagaaagc atcacatccc 7981 gggctacagc gatactttcg gattcattgg gaattccgct tagacccatt acggaagcca 8041 gataaccttc atttacttga ccagaatccg aaagcccttc gtcttcacag tgacttatga 8101 caggaacatt gaatagttga gagtattcca aagctgttct catgacaccg gagtcatgta 8161 cccagcttcc atcatcagaa aaggctactg caccagcaga gtatagatca tccatttcca 8221 caatttcttt acctacccga tcaacagtta gggctgcgat gggatatgtg tgaactagtc 8281 cttgttcttt cgccctctgt ttaataaact caatagtacc actattatca gcagttggtt 8341 tagtatttgg catgcaagct atgctggtaa aaccacctct ggcggcactt tttgtcccag 8401 tggcgatagt ttccttatat tcaaaaccag gttctcttaa atgtacatgc atatcaacta 8461 atccaggtac aatagttagt cctgaaacat caattatttc aagctgctcg gattcggatt 8521 ttcccagctc ctcgggatta atattccttt gttgatcctt aatcatacca tcttctatta 8581 aaatatccat ttgtgttcca tcactaacgg gttctcctgt ataaataata cctcccttaa 8641 gcaatatccc cattatcttc acctccagat aagtgataaa gcaatgccat tcggatagca 8701 actccgttag tcacctgttc ttcaataact gatttttcgc tgttcattag ttcagaagtc 8761 aattcaatac cacgattaac aggtcccgga tgaagtagca aggcatcctt tttagcaagt 8821 ttaaatcttt cttgattaat cccgtataat cgggcatatt ctctcaaact tggtaacagt 8881 gtttttccct gtctttctct ttggattcga agtgccatca caacatcggc atcagccaaa 8941 gcatcttcta ccctgtaata acaactagcc cccatctctg taaacactcg ttgatcaagc 9001 aaagttggag ggcctgcaag tctaacatct gcacccattt tagtaagtcc ccagatatta 9061 gacctggcaa ctcgactgtg ataaatatca ccaattatag ttacctttaa tcctttgaga 9121 gagcctttat attctttaat tgtaaacata tccaaaagcg cctgagtggg atgttcatga 9181 taaccatcgc cggcattaat tattgaacaa gataaattat ttgccagtaa acggggagca 9241 cccgccagtg gatgtcgcat cacaattaag tttattccca tggcttccaa cgtcttccct 9301 gtatcaatta ggttttctcc tttagcaaca ctactagcag aagcactcat atttgtcgta 9361 tcagcaccta agtacttacc cgccatttca aaggatgatc tggtcctggt gctaggttca 9421 taaaataaat tcaccatgga aaagcctttt aatgttggaa gttttttatt ctttctctgt 9481 actatctctt tcatactttc cgttgaatca agaatagatt ctatttctga cttttccata 9541 tcttttaatc ccagtagact ttttcgctgt agacccaatt tttaaccccc tatcataagt 9601 taattgtcaa taaatatcaa caagcaatac tcttcagatg taaaattgac cataaaaaaa 9661 cttcctatgc ttcattttgt gaagctaata ggaagttaca ctaagctaat tggacataat 9721 ttgacacaat acgcctagca tcacctccct tattagcctc acgggactaa tttcaaggga 9781 acttaatctt gtaaattaaa aatcctttat tcctttaccg tctcttcgat catgactctg 9841 tcttctccgt caatttcaga taatctaact gaaattaatt cttttttaga tgtaggaaca 9901 ttcttcccaa catagtcagc tctaattggc agttctcggt gtcccctgtc tacaattact 9961 gccagttgga tatacttagg tctacccaaa tcaattacag catccagagc tgctctggcc 10021 gtcctaccag tgtaaaggac atcgtcgact aatacaactt tcttattttt aatggaaaag 10081 ggaacctcag ttttatttaa aataggtttt tcagataaag tgcttaaatc atcccggtag 10141 agtgtaatat caagtaagcc agtagctata ctttcccctt ctatttcctc aattttatga 10201 gccagtcgtt ctgccagtgg tactcctcga gttctaatgc cgatcagaac aagatcatct 10261 atacctttat ttttctcaat aatttcgtgg gaaatgcgag tcaaagtacg attaaatttt 10321 tcttgatcca tgatctccgc tttttcttga accactttaa cacctccctg gaactcagcc 10381 ccattaaaat atttgtttat aaaaaattcc tatctcagtg agacaggaat attagcaaac 10441 ttatccaaag tatacataat actggagtac tctcccaaaa ttatgtacac atgtagccac 10501 catagatgcc ctcattatcc cttaacagtc tcactggact attttaaagg tcttctattt 10561 gagataaagt ttatctgact ttattgtata tgtcaatact tgcgaattcg acagaatttt 10621 cttgacagtg gcaattttca aattttatta ttaatttacc attatcataa ttttatttca 10681 taattattat tatcataaaa ggaggtgaaa gttggaagaa tactgagaag gataaaatgg 10741 ccttatttgg cacaaatcac aaagaactga agctggaatt ataagaatga gtattgtagt 10801 caatggctgt gtcacttcaa cattttaagg gagggaatta tatggaattt cttttaacga 10861 ttaatgatgc attgaatgaa atagtctggg gtcctccttt tctcatctta ttagttggta 10921 ccggactgta cttaacaatt aggttgagat tctttcagtt tactcatttt gggacgtcct 10981 ggaaggaaac gattattgaa aggattaaaa agactgaatc aggtgaagca ggggctatca 11041 caggctttca ggcgattact tccgccatgg cggcaacgat aggaattgga aatatcgccg 11101 gtgttgctac tgcccttcac ctgggtggac ctggagcgtt attttggatg tggattacag 11161 cccttgtagg tatggctact aagtttgggg aagctgcttt gggagttaag tacagaactg 11221 atgaagacgg agaaatttcc ggtggagtca tgtactatat tcaaaacggt ctaggaaaga 11281 actggatgtg gcttgccatt ttatatgctt tattcgccgg tatcgcagcc tttggaattg 11341 gaaatatggt acaatccaac acagtggctg aagcagtagc agacgatttt ggagttccta 11401 tgtatatcac tggtttggtt gctgctgtgc tagtagctct agttatcttg ggaggaatta 11461 agcgtattgc ccaggtagca gagatcctgg tacccatcat gacggtagtg tatatcttag 11521 gcgcccttgt aattatctta atgcatctac ccgaagttcc aggggcattt agagatatct 11581 ttgtgcatgc ccttaacccc ggtgctgccg gcggaggagc tgcaggagca ggtattatgg 11641 tcgccattcg ctacggtgtt gcccggggaa tcttctcaaa cgaagccggt ctaggtgctg 11701 cctctatcgt acacgcccag gccagaaata ctcccgccaa gcaaggtatg tggggtattt 11761 gggaagtctt tattgacact attctagtcg gtactatgac tgccctggcc attttagtaa 11821 caggagcact agaatcaggt gaaactggtg ctgtattaac atctgaagct tttaacagag 11881 ggttacctgg ccctggtgga gttttcatta ctattgctat tatggttttt gcttatacta 11941 ctatgcttac ctggtctttc tatggagaga aaagttggga atacatcttt ggaccaaaaa 12001 ttcgtattcc ttataggatt atattcttaa ttttaatttt caccggtgca gtaggagcct 12061 tggaagttgt ttgggatttt gcagatacca tgaatggctt gatggcagca ccaaacttaa 12121 tcgctttaat agccttaggt ggagtgctag ctaaagagaa agacaaatac attaacaatg 12181 aattagataa gtaataacaa actcccaaaa agcaatttaa aattttatat aataaagagg 12241 attccctcga gtttttggtt ttagagggaa tcctttttat tttccacatc cgatacaaac 12301 taaatatagg agtattgtga atcgcactaa ataagtaatt tattatatat ttcattatat 12361 atttcaattt agctagaatg cacggatttt tctttgagga agtaagcaca aattaaagct 12421 attaaagaaa atacagcgta aattaaaaaa cccaatcgat aaccgtagac tcctgtatga 12481 cccgtaatat caagtactat tccaataaaa aagttcatca ctgtagtgcc aatgaatgga 12541 gcggtattta tcacactaac agcaattcct gtatatgaag gatcattact ttctttccct 12601 acagcctgac atagcatggc aaaaatagca aaaaagcctc ccataaagta tagaaacgga 12661 aggtgaattg tgggaggggt gccctgccat agcactaact tataaagcca aaatattaaa 12721 aaaacagcag cactaatttg tattaataat tttctatttc caagacgatc ggataactta 12781 cccattactg gagaacctac aataactcct aatgtaaaca caaaaatcaa agaagcagct 12841 tggtctttag caatttcata actggattgc aagtaagtta ctccccagac accagaaaaa 12901 ctcatcattg ctccatgtaa acccattaaa attacaaagc aaaaccatgt attagagttt 12961 gaaagtacac ttttgaagcc tttagataga ttaatagttt taaaactctg agttgaatgg 13021 tgtcggttta tcggaggata gtcaagatcc tggggatcat ctctgacaaa ggtccatatt 13081 aatcctaaga ttataaaaga aaatagaccg attaatataa aagagttttg ccatcctaga 13141 tttagtacca ttacagcaaa gggggttgtg gcgaaaagtg caccggagtt ccccattaaa 13201 gcagaccatc ctgtcatagt tgcaaattct tcaggccggt accacacgga ttgaatttta 13261 aagatgcaaa ttaacaaacc agccacacca attcctacga gaaaacgacc taaatagagc 13321 aaagcaattt cttgcgaaat tcccattaga acagacccgc tcgaggccaa taaaaatccg 13381 attgtagcca ccttccgggg gccgactgta tcagccaata taccagaagg aatctgcata 13441 agagcatagc tgtaaaaata aatagaagca agattactga gcgctgtgcc tgataatgcc 13501 aattcctctc tgagggtatc tgctacaacg ccaagagaat agcgatggaa aaagcccagt 13561 aaataggcaa gggctaacac cccccaaacc acccggcgat agttttttag agaaaaatta 13621 gctgttaatt tcattattta tcaattttcc ttttaaaatt gtgtttttta cttccagttt 13681 ttctgttaat actgctgcat ccgctctttt gccgggtaat aagctgcctc tttcctgtga 13741 caacccaaga attttggccg gtgttaaaga tatcatcttt acagcttcag tcaaagatag 13801 agaggtgaat ttcataatat ttttcagggc ctctggtata gtgagggtgc tgccagctaa 13861 ttgcccttct tgagtttttg cagtgttatt ttttacagta actatctgtt tatctagttg 13921 aaattttccc tcttctaaac cagtccctcg gatggagtca gtaacaagga caattttatc 13981 taagggtttc tgcttaatta ctaaatcaag gatagctgga tgaagatgtt tcccatcgac 14041 aattaattca atggtcgctt caggatgtag gagcaaggct atagcagcac caggagctct 14101 atggtgaatt gcactcatgc cattaaataa atgagccccg tgggataatc ctgcactaaa 14161 agcattgttc atctcttcat aagtagcatc tgtgtgggca gctgacataa ttatgttgtg 14221 tcttctcccc catttaatca gttgagatgc atttttcatt tcaggagcca gagatatcat 14281 gtacaaatgc gccccagcaa gttcccataa ctcgttaaca ctttttaatg aagggggaat 14341 gatatttttc tccgtttgaa ctcccttttt ttctggatta ataaaagggc cttctaaatg 14401 cattcccagt aaattagtgt caatttgatt gctagctttg ttatctaaat attttctgac 14461 agtccctaca gcttgtttga tttccgacca ggatgatgag aaagtagtag ctaaaaaacc 14521 agtcacaccc tgttttaaat agaatgcgct tattttttct agtccttttg tatccgcatc 14581 cattatatcg aatcctagtc cgccgtgagt atgtagatca atgaagcctg gcgccaagta 14641 ttttccctgt aagtcaattt ctttgctctc aatgagcccc aactctccct gatcaataga 14701 agtatcacta ggagccagaa cattatcatc aacatctcga cctaaatccc aaatatagcc 14761 atcgtttccg gctattagat aacccggaga aagaaccccc tgttccgtaa tcaattgtgc 14821 attccgcaaa atcagagcca tataaagccc tccctaaaat aattctacgt actacttagt 14881 tttaagatgt aaaagatgaa tattgataac tgtaaaactt caattaaact taaaagtatt 14941 caggtttggc aacagcttct aaatttaaaa tctttagaat tctcccaatt tcattatatt 15001 gttaatacat actttgaaca acctctttct gcatgactga cttcagtttt tgattaatag 15061 taataattat cttttgttgc taggaggaat ttgggtggtc ttgtagaact cgtctgtcga 15121 aaaggaggtg agatttatag ttaaaaagac catctcatca aggaaaattc cttttttaat 15181 aactatatca tactttgccg cctttataat catcagatta atggtacaaa tagccggttc 15241 tgctgaaagc gagtttgccg atgcagctaa acaggggtta acacccgagg ttgattttta 15301 tattggtagg aatatcattt tattcggtta tcatattcat cacttttatt tcggtatctt 15361 attactcgcc attgcgggtt ggattgccat agtcgggtca aagcatttct ctcgtgaaca 15421 tgctgcgtta tgttatgggg ctggtttggg tttattcatg gatgaaatcg gccttttact 15481 tacatgggga gactactatt ctagcctaac ttatctttta agcttatttt tagctggtat 15541 tttactaaat atagtatttt tcccgtattt ttggaaagat gttaaaaata atttaattgc 15601 cagtagaccc gactccagtt tttggaatcg agcctttaaa aatcataaag tgattgaggt 15661 ggttgataat atgagtgaaa aaacagagca aagcaccaaa gctagtttgg tgttttccgg 15721 aatcgtatac attgccatgg gaggacttat tctaattttc ccggaatttg tatattattg 15781 gatagcaggc gggttcttcc ttcagggaat cgcatctttt gtgaacgctt ggcaacaaaa 15841 agaatctaat taaaaggatg tactgtcaaa ccctcgctta atccgttcaa ttaaatttta 15901 cagtatcaat aactaaatat aacagcgcca attaaaaata gggctagtgg taaattttct 15961 attaccatag ccctttcttg ttttaccgat tcaccaaaca atacctagtt taccgcaaga 16021 aaatgtagtt aatttttgat gttacgacct tgacaggaca tctttgacga ttttacctga 16081 tttcattatt agttgaatat tttttgtatc tgtaatcaag ttaatttctt caacgggatt 16141 accatctatt acaattaaat ctgcttccat accctgtttg atttgtccta cttcaccctc 16201 taaaccgcag gctttagccg ctattttagt tcctgttttt agtgcttctt gacttgacat 16261 aataccatat tccaccatca aagccatttc ccgtgcgtta ttcccctgaa agttataggg 16321 ggtaccagca tctgagccac tagcaacttt aatccccatt tcaacagctt tcctcaaagt 16381 tttaattcta gcttcttttt tatgcttaag cttttctacc atgaagggtg caactccacc 16441 ttctttgccg tattcagtca taaaataatc aggagctaaa gtgggaacat aataaatatt 16501 atgttgtaac atcatttcta aggcttcttc gtcagcgaat gtaccgtgtt ctatggtatg 16561 gacaccggct ttaatggaat tcttgattcc ttctgctcca tgggcatggg atgccacttt 16621 tttattaagt ttatctccct cttcaacaac agcttttatt tcatcaacat ctggttgaac 16681 agcgccagcc accccacctg gattcattat ggctccagtt gccataattt tcaaaacatc 16741 tgcacccagt tttaattgtt cacgggctgc ttccttgaag gcatcgtaac cattaacttc 16801 ttcatataag ccattaaaat actctgatcc gggagcagta atacatagga ttttgccgct 16861 ggtaagaatg cgcggtccgt taataatccc ctgttcaaca gctgctttga cacttatatc 16921 aattccattt acagaaccca agttcctaat tgttgtaaac ccagcctgca gggttgtttc 16981 catttctttt gcagctctaa tagctctcaa tttatcctct actaaatttt catcataggt 17041 atcagccatc ccatgtaggt ctagatgggt atgggcgtca ataaaccctg gcagtaatgt 17101 cctgcctttt aagttataaa cttgacctgt aaattcagct tgatcatctt gtatcgcttc 17161 gtctttatcc aaaacatcag ctattaatcc atctttaatt acaatggtag cattctcaat 17221 tatcttttcc ccatcaaaca acttgacatt ttcaaaaatt atattcttgg ttgtatcttt 17281 cattttacta tcccctttcc aagccactta aaaataaaac cctggccatc attgggccag 17341 ggctgagatt ttgtaatccc atgttcccat atggtcttgt aataataatt atagcagtta 17401 ttccagaaaa agcaagttaa ttatatgcct ctccatcgac aattatagtt acattagaat 17461 gtagtttgac taaactagct ggtaatctag tagttatttc aggagagaac aattgcttga 17521 tcaccggtgc tttttcacta ccattagcta ttatcaggag tttttgggca cttaaaattg 17581 ttcctattcc catagttata gccttatctg gaatggcata atcatctttg gattcattac 17641 ctaaagtttt ttttagtaat tttttattgt ttattattgt ttgatccgat aattcagtca 17701 catgagtgtc ttctctgagg gagtttccag gttcattaaa accgatatgt ccattagtac 17761 ctaaaccaag tatcataaga tctacaggat tttctttgac tttttgttcg taatttgctg 17821 ctgctattat tggatcttct ggattactag gtggaagaaa agtattctct ttatcaatat 17881 caatgtggtc aaagaaataa tagttcatgt aagaatgata gctaatagga ttgtcttcag 17941 atatacctaa aaactcatca atattaaagg ttgtcacatc tttgaaagta agttgccctt 18001 gttgatacct ggagatcagt gactcataca tacctaaagg ggttcttccg gttggcaaac 18061 ccaaaattgt attgggtttt gaaataattt gatctgttat gatttcagct gctttttggc 18121 ttaattggaa atagttatcc actacagtta atttcatgtt tacacctcac agttgaggta 18181 gttatagtca aataatacag attatatttc tgtattatcc tgtgatttta gctttaaaca 18241 atacatcacc cgcttctgtt tcattaccgg aattatattc aacctcttca atccggttag 18301 aatcagttat tacgacagga gttaccagtg atttaccagc ctgttttata atttgatgat 18361 caaattttat taatggctga gattcatcta cctgttcccc ttcttcaacc aaaccttcaa 18421 acccataacc ttctagttgt actgtttcac taccaatatt aatcaaaatt tctaggccat 18481 cttcagtggc taaaccaata ccatgattag tatcaaaggt tttcgttatt ttccccttaa 18541 caggtgacac taaaatccca tcagtttctt ccgagggcgt tatagcagct cctttccctg 18601 cttcgccctg tgcaaattta ggatcttcca cttcatttaa gtcaacaact ttaccagaaa 18661 aaggtgcttt aatctctgtc catttcgaac tagctaccac tctatatctt cctcctttta 18721 ttaatattat aaactatttt ttctaagtac aaattttaat ttcttatagg agttgattat 18781 gtgaccctta atattcttct ttacattcag ctctttttcc tgctaatctt tgcttttttc 18841 acaaggcaat ctaaaataat ggcgctgtta tactccgttg ttgattatca tgttcaggga 18901 tgagtagttg atcaggacgt ttttattcta ctgcttggga gtttttaagt acctgcccga 18961 aatattggat gtgaaaataa agagttcaac tattaacata caactctaat acaactaaaa 19021 gaaaaaaagc tggaaggtaa agtaccactt cccttccagc tttaacaagc cttttctat //