LOCUS NC_010516:6 17730 bp DNA linear BCT 25-AUG-2011 DEFINITION Clostridium botulinum B1 str. Okra, complete genome. ACCESSION NC_010516 SOURCE Clostridium botulinum B1 str. Okra, complete genome. COMMENT locus start: 583870; locus end: 601599 FEATURES Location/Qualifiers source 1..17730 /organism="Clostridium botulinum B1 str. Okra, complete genome." gene 0..524 /gene="" /locus_tag="" /db_xref="583870..584394" CDS 0..524 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MVQSKNKQLVRGALLIAVGLLLPYLFHGIKNAGSIFLPMHIPIL IAGFILSPYFALAVGVLTPLLSHLFTGMPPFPFVYVMVVELLTYGVVISILYNKKKMG IYPSLIIGMLSGRLANILCNYLVLHLIMAKPFKFPVVLAGLFVKGLPGIIIQLILIPI LVKSLGKVELGKAV" gene 526..1116 /gene="" /locus_tag="" /db_xref="584396..584986" CDS 526..1116 /gene="" /locus_tag="" /product="methlytransferase, homolog" /translation="MNDKEFFNNLADKWDDMCFHSKEKIEYILSKANLKEGDRVLDIG SGTGVLIPYLENIISNNGNIAAIDIAENMLKVSKEKNKYSNLKFIVGDFLEYKSKKTF NCITAYSCYPHFKDKDKLAHRAYELLEEGGRLVIAHSESKEKINSRHKDVDHKIKSHI LPKVKYTAELMEKHNFKTIYTEDNEECYIYIGTRNK" gene complement(1202..1441) /gene="" /locus_tag="" /db_xref="585072..585311" CDS complement(1202..1441) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MGIIVNLDVIMAKRKMSLKELAEKINLTNANLSILKNNKAKAIR FSTLEAICRELNCQPGDILEYKEDPSKADKEDELI" gene complement(1462..1944) /gene="" /locus_tag="" /db_xref="585332..585814" CDS complement(1462..1944) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKETFSIKFIKVILMILIFGCTCMLWKYGFMTLFAPEKIPDGFP NIILFLFTTGVYIVVAWNLLKIVFSIDSTPFSLKNVKNFKIIGYLMLFLSLIDAIESI VNFKKSDDLVALGIILDKGIVGIRPSCILYLVLGIMALVLAEIFKKAVKIKDENDLTI" gene 2561..3790 /gene="" /locus_tag="" /db_xref="586431..587660" CDS 2561..3790 /gene="" /locus_tag="" /product="putative nuclease SbcCD, D subunit" /translation="MRILHTSDWHLGKNLEGFSRMDEQERFIEDFINIVDKNNIDMVI IAGDIYDNGNPSARAEKMFYDCIKKVSNKGERLVLIIAGNHDNPERLVAASSLAYDEG IILMGTPKTIVPKGKYGNFKVINSDLACLEIEVKEEKAVIISLPYPSEKRLNEILSKE MDNDEDRRKTYSERIGDIFSNLQEKYYKDNTVNLAISHIFVNGSEETDSERPIQLGGS LAVDVDKLPKKAQYIGLGHLHKPQKVRGIDNAYYSGSPLPYSKSERGYSKGCKIIEAH PGKKAIIEEVYFNNYKPIEVWHCNGIKEAINKCEENKEKDMWLYLHIKTKEYISTEDI KALKEIKKDIVEIVPEIEEKREETFNGNIKEKSMAELFKSFYLNQRGIEASEELMDLF LSIAQEEDEYETEETCD" gene 3765..7295 /gene="sbcC" /locus_tag="sbcC" /db_xref="587635..591165" CDS 3765..7295 /gene="sbcC" /locus_tag="sbcC" /product="exonuclease SbcC" /translation="MKPKKLVIKGLNSFIEKQEIDFETLVNRGLFGIFGPTGSGKSSI LDAITMALYGDIARDSTQFINLDMDSLFVSYEFQIASVDEREDYIVSRTVKRDKKGGY KTTAARLVKNTYEEEEIIADKPRDIQKNIESIIGLTAEDFTRSVVLPQGKFSEFLKLS GKSRRDMLERIFGLEKYGKKLLERIRKARNKEISSLTLIEGRLEQYKDISKEKLQELK IQYENLLKEKSKIAKEKEESNKLYEKYKNIWELQEELNVYLNKLENLKKGLLNIEEKK IKVEKGKNALSVKPYIDELSKIESDRDINKEELQTAMEQLRNIDLNLKNIEEEYKKVS KDKEEEIPLLMQKENNLLQAIEIKKKVEVIKRERADLVQKYKEKESLIRNKNIDKKHI EEDINKISGEVKLKEEEINFLKIDGDRREKIQKLYEIDKEYKRLNLEVCNITERINIK IKSLKEYELKYKDTLETQRDINKKLEYVSDKREDLIKNSPGNNDILLDKKDYINKLME IFNDLNKMNDRKQELEKNLKEKQVVKLNLEKQYKEILQTLKAREEKIMSLEGKIKDIE KMDMASILAANLKEQESCPVCGSMHHIKLAEKVDIKELEILKEDHRNAFKELENIKIE EKEKNILLISVEKEEELILEELENLKEQLKDRNLEDLRGRLQKEKNDFEKLNENIKDW EKEKLILEENINKLQKEKSHIDKEEAKNHEAISKEKELIASIKKDMEEREILFKEKEK EYLNLKEEIKVSNVEEEINRIRASDKKIEEYNKAIKNEREILESENNKREETIKQINI MEIELGKIIEAGKEKKNFIDKEEEEIKKLNVGEISIEHLDQVKKSIGNIKEKEEILKS KLELEVKNREIIWKNKISKEQIKINLEKLYNEKYIQLNKALEENKFHTLEDAKLMLIC KEEIKELEKEIEEFEKEYNSLNINIERVNKKLKGERIEEGSWKDIRLKKENKEKELED IIKNIVIEEKLISDMENNIKALKDLLDEKEKVAHKKALLEDIDKLVQGNKFVEFVAMN QLEYIVFEASKRLKDITRGRYALELDCNGNFTMRDDFNGGGIRPTNTLSGGETFLTSL ALALALSSQIQLKGSSPLEFFFLDEGFGTLDSELLDTVMTSLENLRSDRLSVGIISHV EELKNRVPIKLIVDPAVPGEGGSKIRIEYS" gene 7323..7871 /gene="" /locus_tag="" /db_xref="591193..591741" CDS 7323..7871 /gene="" /locus_tag="" /product="hydrolase, NUDIX family" /translation="MKKLEEKILYEGKWISFKEISYLNNEEKLLKWEAVERTNTTKAV VIVAKLVPTERYVFIKQYRPAIDNYVIGFPAGLLEQEDVEAEAKRELKEETGYVGRVI DISPEIRPNPALLTDYTILVQMEIDENDELNKNPKQELEPSEDIEVMLVSKEESRDFL IEQKNNGVDVGVGPWYIFGFKL" gene 8700..9551 /gene="" /locus_tag="" /db_xref="592570..593421" CDS 8700..9551 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MHFKKENVKRLILVIMGSLIYAIGVNMFLIPHKLLSGGVAGIAI MLQYLTNIQSGYYILLINIPIFLIAFKEVDLDFGIFSFVGMISMSSFLILSRNYMDFY AMNDILISCICGGVLSGAGMGLIFRNRASQGGTDVISVLVKRKFGIKISTIDFMINCV VVTIGALIGSFEVAVYTMISMFVKSQVMGKVIEGFDGKKILFVVTDHDAEIKKQLVER LGVGATIMYGEGAYSGAKRKIIYCIMTTQQIVKAKKIIEDFDEHALISVSNTTECQGG GFKAAAF" gene 10022..10387 /gene="" /locus_tag="" /db_xref="593892..594257" CDS 10022..10387 /gene="" /locus_tag="" /product="putative cadmium resistance transcriptional regulator CadC" /translation="MDKEKQIDTCTCNVIHHDVVDKVKDNMIEEDKAQDLGDFFKVLS EPTRIKILYALSSSEMCVCDISNLLNMTQSAVSHQLKVLRTARLIKFRKDGKVVYYSL DDSHVENVFKQGLEHIMHR" gene 10463..12691 /gene="cadA" /locus_tag="cadA" /db_xref="594333..596561" CDS 10463..12691 /gene="cadA" /locus_tag="cadA" /product="cadmium-translocating P-type ATPase" /translation="MIIKKKLLLKGLHCANCAAKIERAVQKLNIIEEANYNFNNSTLI INLEETHKDSIIKTIQEIVDRIEPGVKVIDKENLKRTVVHAPVKNSSNLKMQNNKEEN LKLDKKENSYEHNHDHSHGHSHDGEDSDELEKKTLIRIISGVVLLILATVLKSKETLS IGLYLASYVLIGGKVILSSIRNISKGQVFDENFLMAVATVAAIGVKQYPEAVAVMLFY EVGEFLQDKAVNKSRKSITSLMNIRPDYANLVRGEDIEVVSPEDINIDDIIMVKPGEK IPLDGIVVEGQSFVDTSAITGESLISEVSKDSNVLSGYINKNGVIKIKITKTFGESTV SKILELTENASATKANTEKFITKFARYYTPVVVFAALALSVIPTLILKDPDISKWIYR AAVFLVVSCPCALVISIPLSFFAGIGGASKKGVLIKTGTALEALNDADTIVFDKTGTL TKGVFKVSKIESEEGVNTEELIEYAALVESYSNHPIAKSILKYYEKTIDNKRIEGYEE IVARGVTAYIDGKKVYAGNNKLMEELNINYKKAQEDGVILYIALEDKYIGYIVINDEI KKDSKETIKSLKDIGIKKAAMLTGDRKSTANNIGTFLGMDEIYSELLPQEKVEKMQTL KSKTSKDGKIVFVGDGVNDAPVLAMSDIGVSMGGLGSDAAIEASDLVLMSDEPSKLVD AIKIARKTHKIVWQNIIIVLIIKFAVLALAIMGKSTMWMAVFADVGVALIAVINALRI LK" gene 13112..13186 /gene="" /locus_tag="" /db_xref="596982..597056" CDS 13112..13186 /gene="" /locus_tag="" /product="tRNA-Glu" /translation="GFLVKRLRRHPLTVESGVRLP*EL" gene 14021..15397 /gene="" /locus_tag="" /db_xref="597891..599267" CDS 14021..15397 /gene="" /locus_tag="" /product="PhoH family protein" /translation="LKLTYVLDTNVILYSPGAIFSFADNDVVIPEVVLEELDSFKKNN NDLGANARHAARIIDKLRKDGSLIDGIVLPGGGTLRVEMNHYDVKLPPSWDKNKPDNR IIQVCKGLKEKGEEVVLITKDTFERIKADTINIDVEDFYEKVVPEYESQYKGRCDAFA SHSTLESFYKNRYMDVESLFFYSEEKNDYYKADININEFILIKSMENPKQTALGRYNG EKVVPLFYKDVKPLGISPRNIGQKFMLEAFLTDSKNAPLVIVKGPAGTAKTLFSLATG LHKVMEEGEDGYRKILICRPNVTMDEDIGFLPGTEEEKIMPFMRPIFDNLEILVDSDE KERYKNEKELYDKIKELFDRRIITTEAVAYLRGRSIVKNWVIIDEAQNLTPKQVKAVI TRVGQGTKLILVGDPDQIDQPFLDSRSNGLCYASEKMRGSKLCYQVTLKDHECERSPL AYEGAKRL" gene 15665..16669 /gene="" /locus_tag="" /db_xref="599535..600539" CDS 15665..16669 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MENKEKKSKNKKFSFKIFLYFIIFELFFTAATAPFIIFHGPFKN VKKTMVGAAMTTLKHQYIAKTFLSDAKIKEILGEDSIQTIKQDKNSVLKFENKHDSTI ERYDISYGKKFKGYMLVVHDPSRVKVGYSSKLPVQGELTSQIARNKRAVAAINAGGFT DKSANSKWTGTGGNVEGVIISKGEIKYNSNKQGEFTGDVAAITKKGALVVGKHSIQEL KDLNVQEAITFGPALVVKGQGTITSGDGGWGMAPRTAIGQREDGAILMLVIDGRQASS LGATLKDVQDIMLQYDAYTATNLDGGSSTTMYHEGEVINNPANSLGERSVPSILYVEP" gene 16679..17695 /gene="" /locus_tag="" /db_xref="600549..601565" CDS 16679..17695 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKVVKKIILWVMISLTLQFAGLFYIDKYFLASGGTRIKAKKVTN TGTENKDYDVNIPENVEELDVSFNGKYISYFKDNKLNIISTKNGEKKNIEFDSKKDKL EYIWLSDRNRIIYAENKEGQVLLNSYDVDKDQKDKICEFNFESSSAKIEDIKAAPLMN LIYVKVNVGGNNNRLYSVNIMKEKDRIDIMTEAVGDMNIIPHEDILIYEDKINKKIFA THNESSINIGGVTSPKLLSIDDNDNVYIGELKEDEVVKIYYGNVKNNTSTWKALDIPN GAKVKDIYVSPLGSVYVNDDLKGVIKEISTGKETKYSGVMMKMYIDGVASISDGKLVK TKFK" ORIGIN 1 atggtacaat caaaaaataa gcaattggtt agaggggcat tattaatagc agtagggtta 61 ttattgcctt atttgtttca tggaataaaa aatgcaggat caatattttt accaatgcat 121 attccaattc ttatagcagg ttttatattg agtccttatt ttgctttagc agtaggagta 181 ttaactccct tattgagtca tttatttaca ggtatgccac cattcccatt tgtctatgta 241 atggtagttg aattattaac ttatggagtg gttatatcaa ttttatataa taaaaagaaa 301 atgggaatat atccatcatt aataatagga atgttaagtg gaagattggc taatatatta 361 tgtaattatt tagttttaca tttaataatg gcaaaacctt ttaaatttcc agttgtatta 421 gcagggttat ttgtaaaagg tttgccgggt ataattattc aattaatact tatacctata 481 ttagttaaat cattagggaa agtagaatta ggaaaggctg tataatatga atgataaaga 541 gttttttaat aatttagcag ataagtggga cgatatgtgt tttcattcaa aagagaaaat 601 agaatatatt ctttcaaaag caaatttgaa agaaggagat agagttttag atataggtag 661 tggtacagga gtacttatac cttatttaga aaatattatt tctaataatg gtaatatagc 721 tgctatagat atagcagaaa atatgttaaa ggtatcaaaa gaaaaaaaca aatactctaa 781 tttaaagttt atagtaggag attttttaga gtataaatct aaaaaaactt ttaattgcat 841 aacagcatat tcttgttatc ctcattttaa ggacaaggat aaattagcac atagagccta 901 tgaactactc gaggaaggtg gtagattagt tatagctcat agtgaaagta aagagaagat 961 aaactctaga cataaagatg tagatcataa gataaagtca catatattgc ctaaggtgaa 1021 atatactgca gaattaatgg aaaaacataa ttttaaaact atatatacag aggataatga 1081 agaatgttat atttatatag gtacaagaaa caaataattt gattagataa attttatgta 1141 tgattaacca aaataaaagt gtggagtaaa aatataaaaa ctactccaca cttttacttt 1201 atttaaatta attcatcctc tttgtcagcc ttgcttggat cttctttgta ttctaaaata 1261 tctccgggtt gacaattcaa ctccctgcat atagcctcta aggtagaaaa tcttatagcc 1321 tttgctttgt tattttttag aattgataag ttagcattag ttaaattaat tttttcagct 1381 aattctttaa gagacatctt tcgttttgcc attataacat cgagattaac tataattccc 1441 atacaaaatc tcctatcctg tgttatattg ttaaatcatt ttcatctttt attttgacag 1501 cttttttaaa aatctcagcc aaaactaaag ccataatacc taacactaaa tataaaatac 1561 aacttggtct aataccaaca attcccttat ctaaaataat acctaaagcc acaagatcat 1621 ctgatttttt aaaatttact atactctcta tggcatctat aagagataaa aataacataa 1681 gataacctat tattttaaag tttttaacat tttttaagga aaaaggggta gagtctatac 1741 taaacacaat ctttaagaga ttccatgcaa caacaatata aactccagtg gtaaatagga 1801 aaagtataat attaggaaaa ccatcaggta ttttttctgg agcaaataaa gtcataaaac 1861 catatttcca aagcatacat gtacaaccaa atattaaaat cattaaaatt actttaataa 1921 attttattga aaaagtttct ttcataaata aattactcct atctatgttt ttatatggat 1981 gaactagaaa attttgtatt ttacaattat aatatacagc atatcttatt gtgtgtcaat 2041 aatatattat tgaattacga taatatctta ttgtttatag ataaaattat ccgaaggcta 2101 tccgctctaa tgctcctatt ttcttcaaag tggaagtaaa gagtggttac gtccttggat 2161 aaccattttc taagctctag taggagcaaa aactccttct gaagctaaga accttgttta 2221 ttataaatat aataatacta ctctttttaa agatcttagt ttttatagat aagaggggaa 2281 ttacatttat aagcgtaaca atagttacat tctaaaaaat atatatctat ggtttgaaag 2341 agattctata ctatatattt accaaaagat ttaaatatag ctacaagtag caatagttta 2401 cgttataata taaataataa tatgatttgt ttatttttat tttttgatat tttatagtat 2461 agataacaat ataatttatt tttatataga ttgtgagtag aataagcaaa ataatttaat 2521 aagatggaaa gttaactaga tacaaaaggg agatgaagat catgagaata ttgcatacct 2581 ccgattggca cttgggaaag aaccttgaag gctttagtag aatggatgaa caggaaagat 2641 ttatagagga ttttattaac attgtggata aaaataatat agatatggtg ataatagctg 2701 gagatatata cgataacgga aatccatcgg ctagagcaga aaaaatgttt tatgattgta 2761 taaaaaaagt aagcaataag ggagaaagat tagttttaat tatagcaggt aatcacgata 2821 atccagaaag attagttgct gcaagttctt tagcctatga tgagggaata atacttatgg 2881 ggactcctaa gactatagtt ccaaagggaa agtatgggaa ttttaaggta ataaattcag 2941 atttagcctg tttagaaata gaggtaaagg aagaaaaggc agtgattata tctttacctt 3001 atcctagtga gaaaagatta aatgaaatac tgtctaaaga aatggataat gatgaggata 3061 gaagaaaaac ttattcagaa aggataggag atatattttc taatttacag gaaaaatatt 3121 ataaagataa cactgttaat ttagctattt ctcatatatt tgtaaatgga tcagaggaaa 3181 cagattctga aaggccaata caacttggag ggagtctagc agtagatgta gacaagttac 3241 ctaaaaaagc ccaatatata ggtcttgggc atctgcataa accacaaaag gtaaggggga 3301 tagataatgc ctattattct ggctcaccac tgccttatag taaaagtgaa agaggatata 3361 gtaaaggatg caagataata gaggcacatc cagggaaaaa agctattatt gaagaggttt 3421 attttaataa ctataaacct atagaggtat ggcattgcaa cggtataaaa gaggctataa 3481 ataaatgtga agaaaataaa gaaaaggata tgtggctata tttacatata aaaacaaagg 3541 aatatataag tacagaagat ataaaagcct taaaagaaat aaaaaaagat atagtagaga 3601 tagtaccaga aatagaggaa aaaagagaag aaacttttaa tggaaatata aaagaaaaat 3661 ctatggcaga attatttaaa tccttttatt taaatcaaag aggaatagag gctagtgaag 3721 aattaatgga tttattttta agtatagctc aagaggagga tgaatatgaa accgaagaaa 3781 cttgtgatta aagggctaaa cagttttata gaaaaacagg aaatagactt tgaaacttta 3841 gtcaatagag gtttgtttgg catatttggc cctacaggca gtggaaaatc cagtatatta 3901 gatgctataa ctatggcttt gtatggagat atagcaagag atagtactca gtttataaat 3961 ttagatatgg attctttatt tgtaagctat gagtttcaga tagcatcagt agatgaaaga 4021 gaagattata ttgtttctag aactgtaaaa agagataaaa aaggtggtta taagactacc 4081 gcagctaggt tagttaaaaa tacttatgag gaagaggaaa taatagcaga taagcctaga 4141 gatatacaaa aaaatataga gtctataata ggtttaacag cagaagattt tactcgctca 4201 gtagtattac cacaaggtaa atttagtgag tttttaaagt taagtggaaa aagtagaaga 4261 gatatgttag agagaatatt tggattagag aagtatggca aaaaactttt agaaagaata 4321 agaaaagcaa gaaataagga aatatcctct ttaacattaa tagaaggaag attagaacag 4381 tataaagata tatccaagga aaaattacag gaactaaaaa tacaatatga aaatttgtta 4441 aaagaaaaat ctaaaatagc gaaagaaaaa gaagaaagca ataagcttta tgaaaagtat 4501 aaaaatatat gggaacttca agaggaatta aatgtttatt taaataaatt agaaaatctt 4561 aaaaaagggt tgctaaatat tgaagagaaa aaaataaaag tagaaaaggg aaagaatgca 4621 ttaagtgtta aaccctatat agatgaactt agcaaaattg aatcagatag agacataaat 4681 aaagaggaat tacaaactgc aatggagcag ttaagaaata tagatttaaa tttaaaaaat 4741 atagaagaag aatacaagaa agtatcaaag gataaagaag aagaaatacc tttattaatg 4801 cagaaagaaa ataatttact acaggctata gaaataaaga agaaggttga agttataaaa 4861 agggaaagag cagatttagt acaaaaatat aaggaaaagg aaagcttgat aagaaacaaa 4921 aatatagata aaaagcatat agaggaagat ataaataaga tttctgggga agtaaaatta 4981 aaagaagaag aaataaattt tttgaaaata gatggagaca gaagagaaaa gatacaaaaa 5041 ctatatgaaa tagataaaga atataaaaga ttaaatttag aagtttgcaa tataacagaa 5101 agaataaata taaaaataaa gagcttaaaa gagtatgaat taaagtataa agatacatta 5161 gaaacacaaa gagatataaa taaaaaatta gaatatgttt cagacaaaag agaagattta 5221 ataaaaaact ctcctggtaa caatgatatt ttgcttgata aaaaagatta tataaataaa 5281 ttaatggaaa tttttaatga tttaaataaa atgaatgata gaaaacagga attagaaaaa 5341 aatttaaaag aaaaacaagt agtaaaatta aatttagaaa aacaatataa agaaatatta 5401 caaacattaa aggctagaga agaaaaaatt atgagcctag agggaaaaat aaaagatata 5461 gaaaaaatgg atatggcctc tatattagct gctaatttaa aggaacaaga atcttgtcct 5521 gtatgtggat ctatgcatca tattaaatta gctgaaaagg tagatataaa agaattagaa 5581 attctaaaag aagatcatag aaatgcattt aaagaattag aaaatataaa aatagaagaa 5641 aaagaaaaaa atatactttt aatttctgtg gaaaaagaag aagaattaat attagaggaa 5701 ttagaaaatt taaaagagca attaaaagat agaaacttag aggatttaag gggaagacta 5761 caaaaagaaa aaaatgattt tgaaaaatta aatgaaaata taaaagactg ggaaaaagaa 5821 aaattaatat tagaagaaaa tataaacaag ctacaaaaag aaaaaagcca tatagataaa 5881 gaggaagcta aaaatcatga agctatatca aaggaaaaag aattaatagc ttctataaaa 5941 aaggacatgg aagaaagaga aatattattt aaggaaaaag aaaaagaata tttaaattta 6001 aaagaagaaa ttaaagtttc taatgtggaa gaagaaataa atagaattag agcttctgat 6061 aaaaaaatag aggaatataa taaggctata aaaaatgaaa gagaaatttt agagagtgaa 6121 aataataaaa gagaagaaac aattaaacag ataaatatta tggaaataga gctaggcaaa 6181 ataatagaag cgggaaaaga aaagaaaaat tttatagaca aagaagagga ggaaataaaa 6241 aaattaaatg tgggagagat ttctatagaa catttagacc aagtaaaaaa atccataggg 6301 aatataaagg aaaaagaaga aatcttaaaa tctaagttgg agttggaagt taaaaacaga 6361 gaaataatat ggaaaaataa aataagtaag gaacaaataa aaattaactt agaaaaactt 6421 tataatgaaa aatatattca gttaaataaa gccttagagg aaaataaatt tcatacttta 6481 gaagatgcaa aattaatgct aatatgtaaa gaagaaataa aagaattaga aaaagagata 6541 gaagaatttg aaaaagagta taatagttta aatataaata tagaaagagt aaataaaaaa 6601 ttgaaggggg aaaggataga ggaaggaagt tggaaagata taaggcttaa aaaagaaaat 6661 aaggaaaaag aactagaaga tataattaaa aatattgtaa tagaagaaaa acttataagt 6721 gatatggaaa ataatataaa ggcactaaag gacttattag atgaaaaaga aaaggtagct 6781 cataaaaagg ctttattaga agatatagat aaattagttc agggaaataa atttgtagag 6841 tttgtggcta tgaatcagtt agagtatata gtttttgaag cttctaaaag acttaaggat 6901 ataacgagag gaagatatgc attagaatta gattgtaatg gaaactttac tatgagggat 6961 gactttaatg gagggggtat aagacctaca aatactttgt ctggagggga aaccttctta 7021 acatcattgg cactagcttt ggcgctatct tcacagatac aactaaaagg aagctcccct 7081 ttagaatttt tctttttaga tgagggattt ggaactttag atagtgagct tttagataca 7141 gttatgactt ccttagaaaa tttaagaagt gatagattaa gtgtaggaat aataagtcat 7201 gtagaggaac ttaaaaatag agtaccaata aaacttatag tagatcctgc ggtaccagga 7261 gagggtggaa gtaaaataag aatagagtat agctagtagt agataattta tggaggtaat 7321 tagatgaaga aattagaaga gaaaatatta tatgaaggta aatggataag ttttaaggaa 7381 ataagttatt taaataatga agaaaagctt ttaaaatggg aagcagtaga gagaaccaat 7441 acgactaaag ctgtggttat tgtggcaaaa ttagttccaa cagagcgata tgtatttata 7501 aaacaatata gaccagctat agataattat gttataggat ttcctgctgg attattagaa 7561 caggaagatg ttgaagcaga ggctaaaaga gaattaaaag aagaaacagg ctatgtaggt 7621 agggttatag acataagtcc agagataaga cctaacccag ctttattaac agattacact 7681 atattagttc aaatggagat tgatgaaaat gatgaattaa ataaaaatcc taagcaagaa 7741 ctagaacctt cagaggatat agaggttatg ttagtgtcta aagaagaaag tagagacttt 7801 ttaatagaac aaaaaaataa tggagtagat gtgggagtag gtccttggta catatttgga 7861 tttaaattgt aattaatttt ttattaaaat aatataattt tgttttttat ttaaatagag 7921 gaaataagat gtttcaaaat aaaatttatt ttgaaacatc ttattttttt tgtttcataa 7981 agtaagtaat aaaaaataga aaaaatttat caatatttta attaaattgc aaagtatttc 8041 tatgtaataa ttttatataa aaaatatata caattaatga aaaatatata taagtttaaa 8101 aaatatataa catttgcata attcccatca aaaaagaaat gaaataaaaa tttcattggc 8161 gtataattgg gatataatta aatatagtaa catattatta acgaaactag aatctattga 8221 taaataatag gttgacacat tataaaaata tttatatatt aaataaaaag aaggttttta 8281 ttcatttttt taagatattt gtaaaataaa aatttaattt atgaattaaa aaaatataaa 8341 aaatatttat ttgatgaaaa tgcaagtttt cattcaatat gtttcatagc tactatttaa 8401 tcttacaaaa attttataca atataatcta tcaggataaa aaagcaaaga aaataaagga 8461 aaataaaaat atcatcgttg cacaatccat agtagcctaa taaaaaaata aacggggtgt 8521 taaagatatg tttgacagtg ggtaatatat taaattccct aataaatgaa tatttgaaaa 8581 ttaattattc atttacctaa aaataattac taataaaaat attttttaaa agaataaaca 8641 tataaattta tatgttatag taaaaaaagt ctaattttgt tttggaggtt tttatttatc 8701 atgcatttta aaaaagaaaa tgtaaaaagg ttaattttag taataatggg aagtttaata 8761 tatgccatag gagttaatat gtttcttata ccacataaat tactaagtgg tggagttgct 8821 ggtattgcaa taatgttaca atatttaact aatatacaat caggatatta tattcttctt 8881 ataaatatac ctatatttct tatagctttt aaagaagtgg atttagattt tgggattttt 8941 agctttgtag gaatgataag catgtcttca tttttaattt taagtagaaa ttatatggac 9001 ttttatgcta tgaatgatat tttaatttct tgtatatgcg gtggtgtttt aagtggagct 9061 ggtatgggat taatatttag aaatagagct tcacaaggag gaacagatgt aatatctgtt 9121 ttagtaaaaa gaaaatttgg aataaaaata tcaactatag attttatgat aaactgtgta 9181 gtagttacta taggagcatt aataggaagt ttcgaagtag ctgtttatac aatgatatct 9241 atgtttgtaa agtcacaggt tatgggaaaa gttatagaag gttttgatgg taagaagata 9301 ctatttgttg taacagacca tgacgcggaa ataaaaaaac aactggtgga aagattaggg 9361 gtaggtgcaa ctattatgta tggtgaaggc gcttattctg gagcaaaaag aaaaataata 9421 tattgtataa tgactactca acagatagta aaagctaaaa aaataataga agattttgat 9481 gaacatgcat taatatctgt atctaatact acagaatgtc aaggtggagg ttttaaagca 9541 gcggcctttt aaaaataaaa aaataataag attaattatt aattgagaaa ataatgaggg 9601 tttatattaa aatactttta atataaaccc tcatttttat ctttaattag tggctagctt 9661 caaagcttcc acaatctgtg gattcaacac ttgcagcctc atgtgtatgc ttagttactt 9721 ggattttgtt aagtgtacaa tagtctgtgc tttgagcgtg atatttacat tcgtgaacac 9781 tacatcctat actatcatta tgattcatat taaattacct cctacaaatt gaaatgtttt 9841 tttatttctc tattattatt tgattataga ttttttttat gtgtagaaaa aatagtaaat 9901 tatttttaaa ataatattgt aatttaaaaa taaatgtgat acattatatt taaacatatg 9961 aacaattatt catgtgttca catataatat taattaggat agagataaag gagaatgcaa 10021 atatggataa agaaaaacag atagatactt gcacatgcaa tgtaattcat catgatgtag 10081 tagataaagt taaagataat atgatagaag aagataaagc acaggattta ggagattttt 10141 ttaaggttct atcagaaccg actagaataa aaattttata tgcattatca tcatcagaaa 10201 tgtgcgtatg tgatatttca aatcttctta atatgacaca atcagcggtg tctcatcaac 10261 ttaaagtttt aagaacagct agacttataa aatttagaaa agatggtaaa gttgtttatt 10321 attcattaga tgactcacat gtagagaatg tatttaagca aggactagaa cacataatgc 10381 atagataaaa ttaagtttaa tattttattg taattttaga aattttgatt ttttaataat 10441 tattttagaa ggatggtggg attatgatta taaaaaagaa attgctttta aaaggcttac 10501 attgtgccaa ttgtgcagcg aaaatagaac gagctgtgca aaagctaaat ataatagagg 10561 aagctaacta taattttaat aattcaactt tgattattaa cttagaagaa actcataaag 10621 acagtattat aaaaacaata caagaaatag tagatagaat agaacccggg gtaaaggtaa 10681 tagataaaga aaatttaaaa agaacagtag tgcatgcccc tgttaaaaat agtagtaatt 10741 taaagatgca gaataataaa gaggaaaatt tgaaattaga taaaaaagaa aatagttatg 10801 agcacaatca tgatcatagt catggacaca gtcatgatgg agaagatagt gacgagttag 10861 aaaagaagac tcttataaga attatttcag gagtggtttt attaatttta gctaccgtat 10921 tgaaatctaa agaaactttg tctataggtc tatatttagc ttcatatgta ttaattggag 10981 gtaaggtaat attaagttct ataagaaata tatctaaagg acaagtattt gatgagaact 11041 ttttaatggc tgttgcaact gtagcggcta taggagtaaa acagtatcca gaagcagtag 11101 cggttatgct attttatgaa gtaggggagt tcttacaaga taaagctgtt aataaatcta 11161 gaaaatctat aacatcactt atgaatataa gacctgacta tgccaattta gttagaggtg 11221 aagatataga agtagtttct ccagaagata ttaatataga tgatattata atggtaaaac 11281 cgggagaaaa aattcctcta gatggtatag ttgtagaagg acaatctttt gtagatacat 11341 cagctataac aggtgaatct ttaataagtg aagtttcaaa agatagtaat gtattaagtg 11401 gatatataaa caaaaatggt gttataaaaa taaaaattac aaaaaccttt ggagaatcta 11461 cagtgtccaa aatattggaa ttaacagaaa acgcatcagc tactaaggca aatacagaaa 11521 aatttataac aaagttcgcc agatattata ctcctgtagt tgtttttgct gctttagctt 11581 tatcagtaat tcctacacta atactaaaag atccagatat atctaaatgg atttatagag 11641 cagctgtatt tttagtagta tcttgtccat gtgctttagt aatatcaata cctttaagct 11701 tctttgctgg tattggaggg gcatctaaaa aaggcgtttt aataaaaaca ggaacagcat 11761 tagaagctct aaatgatgca gatacaatag tatttgataa aacaggaact ctaactaaag 11821 gtgtgtttaa agtatcaaaa attgagtcag aagaaggagt aaatacagaa gaattaatag 11881 aatatgcggc tttagtagaa agttattcta atcaccctat cgcaaaatct atactaaagt 11941 attatgaaaa aaccatagat aataaaagaa tagaaggtta tgaagaaata gttgcaagag 12001 gtgtaactgc ttatattgat ggcaaaaaag tttatgctgg taacaataaa ttaatggaag 12061 aattaaatat taactataaa aaagctcaag aggatggagt aatcctttat atagcattag 12121 aagataagta tataggttat atagttataa acgacgaaat aaagaaagat tcaaaagaaa 12181 caataaaatc attaaaagat ataggcataa aaaaagcagc tatgcttaca ggagatagaa 12241 aatctacagc taataatata gggacttttc taggaatgga tgaaatatac tcagaacttt 12301 taccacagga aaaggtagaa aagatgcaga ccttaaagtc taaaacatct aaagatggaa 12361 aaattgtttt tgtaggagat ggagtaaatg atgctccagt attagctatg tcagatatag 12421 gggtatccat gggaggatta ggatctgatg cagctataga agcatctgat ttagttttaa 12481 tgtctgatga gccatcaaaa ttagtagatg ctataaaaat agcaagaaaa actcataaaa 12541 tagtatggca aaatataatt atagttttaa taattaagtt tgcagtatta gctctagcta 12601 taatgggaaa aagtactatg tggatggctg tctttgccga tgtaggtgtg gctttaatag 12661 cagtaataaa tgcattaaga atactaaaat aaaaatttac taaaataata actttctaaa 12721 gaacaatagg aacgaatgat tttaaagaaa aatatttaat tatatttata tagtttcagt 12781 taagtaattt taggttcaga tggagtttgc ttagaacaat tatttttctc catctgaaca 12841 ttattattta tcagagagta ataaatatag aagattaatt tttatgaaag tataaaaaat 12901 tatcaaattg tataaacaga aatatactta tgagaaatta taagatgagc attaggtact 12961 tttatacatt cttgaataaa tgttatgcaa aaataaaaga tttaataatt taataaaaaa 13021 attaaaaaca aaagaaaata tttctaaaaa atattgactt aaaatttagg ctgtaatata 13081 attatagatg ttcaaagaaa ataaataatt gaggcttctt ggtcaagcgg ttaagacgcc 13141 accctctcac ggtggaatca ggggttcgac tcccctagga gctaccagat ttgaagaaat 13201 gctgcaaaca ctagtacttt tagtattttt ttatttaaat tttaaaatta agcatcgcaa 13261 tttattatgt ttgtttgctt tcaagatttt gtttttgagc tgcaatagtt aacaaaatag 13321 ttccgattgc agaaaggaga tttccaagta catttactta attggcatta ttccctttag 13381 ataattataa ggctattaaa tcagtagaga tagataattt aacagcctta tataatttaa 13441 gtccttcaca tatataactc cttttgtagt atataatata ttaaattatg taatataaaa 13501 tttgtttaat aaagtactct tatcaataat aaaaaatcaa ctatttagta tataaatatg 13561 ataagtatat aataaaatta aagtttggga gtaatatgga agtgtttttt aatctagatg 13621 tttttaatta tttttaaaga ataaatatta ggaagattta gaaaaaatat tgacaggtct 13681 taagaggtga tgtatagttt tattaagcgg tataatttac tacttaataa aactattttt 13741 actatttatt attatattat ataggggaca ttcttattta cgcctcttta ttttattttt 13801 atttaaaagg atttctattg atatatagag gtcctttttt atttaaaaga tttttgttaa 13861 tataaaaatt tttttatttc aaatcatata tataataaat taaataattt aaaaaatata 13921 atattaaaag tctataaata tttttaattt aataaaatag agaatttaat aaagttataa 13981 ctttatctga atataataat ataaagaagg gaggagtaga cttgaaacta acttatgtat 14041 tagatactaa tgttattttg tattcaccag gagctatatt ttcttttgca gataatgatg 14101 tagttatacc tgaagtagtt ttagaagaat tagatagctt taaaaagaat aataatgatt 14161 taggggctaa tgctaggcat gcagcaagaa taatagataa attaagaaaa gatggaagtt 14221 taatagatgg catagtatta cctggtggag gaactttaag ggtagaaatg aatcattatg 14281 atgtaaaatt gcctccgtct tgggataaga ataagccgga taacagaata atacaggttt 14341 gtaagggatt aaaagaaaaa ggggaagaag tagtattaat tacaaaggat acctttgaga 14401 ggataaaggc ggatactatt aatatagatg tagaagattt ttatgaaaaa gtagtaccag 14461 aatatgaaag ccaatataaa ggaagatgtg atgcttttgc atctcacagt actttagaaa 14521 gtttttataa gaatagatat atggatgtag agagcttatt tttttattca gaagagaaaa 14581 atgattacta taaagcagat attaatataa atgaatttat attaattaaa tctatggaaa 14641 atccaaaaca aacagctctg ggaagatata atggagaaaa agttgttcct cttttttata 14701 aagacgtcaa gcctttagga ataagtccta gaaacatagg acaaaagttt atgttagaag 14761 cttttttaac agattctaaa aatgcacctt tagttatagt aaagggacct gcaggtacag 14821 ccaaaacttt attttctcta gctacaggac ttcataaagt tatggaagag ggagaagatg 14881 gatatagaaa aattttaatc tgtagaccta atgtaactat ggatgaagat atagggtttt 14941 tacctggaac agaggaagaa aaaataatgc cttttatgag acctattttt gataatttag 15001 agattttagt ggattctgat gaaaaggaaa gatataaaaa tgaaaaagaa ttatatgata 15061 agataaaaga gttatttgat aggcgaatta taactacaga agcggtagct tatttgagag 15121 gtagatctat agtgaaaaat tgggttataa tagatgaagc tcaaaattta acaccaaagc 15181 aagtgaaggc ggttataact agagtaggac aaggaacgaa acttatatta gtaggtgatc 15241 cggaccaaat agaccaaccg tttttagact ctagatcaaa tggtttatgt tatgcatcag 15301 aaaaaatgag gggaagcaaa ctttgttatc aggtaacatt aaaggatcat gaatgtgaaa 15361 gatcaccatt agcctatgag ggagcgaagc gattataatt ttatactata tgtaagtaga 15421 gggtgcctca aaatcaaata tattttgagg tgccctctat attttatgtg atataattta 15481 ttacaatcag atttatgtaa gttaatgtat aaatagtttt aatttagaaa atatattgca 15541 gtttaaaggg aaataaaatg aattttagga agttttacaa tatttcataa agcttactat 15601 ttaaaaaaat ttatatttag tgtacaataa tgaaagatgt aaaataaaga gaaaggaatt 15661 tttagatgga aaataaagag aaaaagtcga aaaacaagaa attttctttt aaaatatttt 15721 tatattttat aatttttgaa ttgtttttta cagcagccac agcgcctttt ataatattcc 15781 atggtccttt taaaaatgtt aaaaagacta tggtaggagc agctatgact actttaaaac 15841 atcaatatat agctaaaaca tttttatcag atgctaaaat aaaagagata ttaggtgaag 15901 attctataca aactataaaa caagataaga actctgtgtt aaaatttgaa aacaaacatg 15961 atagtacaat agaaagatat gatataagtt atggcaaaaa gttcaaagga tatatgttag 16021 tagttcatga tccatctagg gtaaaggttg gatatagttc taagttacca gtacaaggag 16081 aacttacaag tcagatagca agaaataaaa gagccgttgc agcgattaat gcaggtggct 16141 ttacagataa atcagctaat agcaagtgga caggcaccgg tggaaatgtt gaaggagtaa 16201 taattagtaa aggtgaaatt aaatacaata gtaataagca aggagaattt acaggagatg 16261 tagcagctat aactaaaaag ggggctttag ttgtaggtaa acatagtata caagaattaa 16321 aagatttaaa tgtacaagaa gctataactt ttggaccagc cttagtagta aaggggcaag 16381 gcaccataac ttctggagat ggtggatggg gaatggcgcc tagaactgct attggacaaa 16441 gagaagacgg agctatactt atgctggtta tagatggtag gcaagcatct agtttaggag 16501 ctacattaaa agatgtacaa gatataatgt tacaatatga tgcatatact gctacaaatt 16561 tagacggtgg atcttcaact acaatgtacc atgaaggaga agttataaat aatcctgcta 16621 attctttagg agaaagatca gtaccatcta ttttgtatgt tgaaccttag gaggaaaata 16681 tgaaagtagt aaaaaaaata atattatggg taatgatttc attaacatta caatttgcag 16741 gattgtttta tattgataaa tattttttag catcaggggg aacacggata aaggctaaaa 16801 aagttacaaa tacgggaacg gaaaataaag attatgatgt aaatatacca gaaaatgtag 16861 aagagttgga cgtatccttt aatggaaaat atatttccta ttttaaggat aataaattaa 16921 atataattag tactaaaaat ggtgagaaaa agaatattga atttgatagt aaaaaagata 16981 aattagaata tatatggctt tcagatagaa atagaattat atatgcagaa aataaagaag 17041 ggcaagtatt attaaattct tatgatgtag ataaagatca aaaggataaa atatgtgaat 17101 tcaattttga aagttcaagt gctaaaattg aagatataaa agcagcacca cttatgaatt 17161 taatatatgt taaggtaaat gtaggtggca ataataatag attatatagt gttaatataa 17221 tgaaagaaaa agatagaata gacataatga cagaggcagt tggggatatg aatataattc 17281 ctcatgaaga tatattaatt tatgaagata aaataaataa aaagattttt gctacacata 17341 atgaatcatc tataaatata ggaggagtaa catcaccaaa attgttatct atagatgata 17401 acgataatgt atatatagga gaattaaagg aagatgaagt agtaaaaatt tattatggta 17461 atgtaaaaaa taacacatct acttggaaag cattagacat acctaatgga gctaaagtaa 17521 aagatattta tgtttcacca ctaggaagtg tatatgtaaa tgatgactta aaaggtgtta 17581 taaaagagat aagcacagga aaagaaacaa agtattctgg agttatgatg aagatgtata 17641 tagatggagt agcttctatt agtgatggta aattagtaaa aaccaaattt aaataataat 17701 ataaaattca aatgtatatg aaaataatta //