LOCUS NC_010382:6 18636 bp DNA linear BCT 06-OCT-2011 DEFINITION Lysinibacillus sphaericus C3-41, complete genome. ACCESSION NC_010382 SOURCE Lysinibacillus sphaericus C3-41, complete genome. COMMENT locus start: 4479464; locus end: 4498099 FEATURES Location/Qualifiers source 1..18636 /organism="Lysinibacillus sphaericus C3-41, complete genome." gene complement(0..698) /gene="" /locus_tag="" /db_xref="4479464..4480162" CDS complement(0..698) /gene="" /product="50S ribosomal protein L1" /translation="MAKKGKKLQDAAKLIDRNSLYSAQEAIELAQKTSTVNFDATVEV AFRLGIDTRKNDQQIRGAVVLPNGTGKTQRVLVFAKGEKLKEAEAAGADYVGDAEYIQ KIQQGWFDFDVIVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAIEEIKAGK VEYRADKAGIIHAPIGKVSFSAAKLVENFLAVFDVVQKAKPAAAKGTYMKSVNITTTM GPAVKIDAANVVVK" gene complement(815..1240) /gene="" /locus_tag="" /db_xref="4480279..4480704" CDS complement(815..1240) /gene="" /product="50S ribosomal protein L11 (BL11)" /translation="VAKKVIKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNA RTADQAGLIIPVEISVFEDRSFTFITKTPPAAVLLKVAAGIQSGSGEPNRKKVATVKR DKVREIAETKMPDLNAASVEAAMLMVEGTARSMGIVIED" gene complement(1498..1842) /gene="nusG" /locus_tag="nusG" /db_xref="4480962..4481306" CDS complement(1498..1842) /gene="nusG" /product="transcription antitermination protein" /translation="MMRKVFPGYVLVELIMTDDSWYVVRNTPGVTGFIGSSGGGAKPT PLLPEEADRLLQQMGMTDKIVEVDISIGEAVEVLEGPFAHFQGRVEEIDTEKGKIKVS VDMFGRETMYGV" gene complement(2345..2497) /gene="" /locus_tag="" /db_xref="4481809..4481961" CDS complement(2345..2497) /gene="" /product="transcription antitermination protein NusG" /translation="MSEMRKTSWPKSKELTKYTVVVISTVVVMALFFVLVDLGISSLF RWYLDL" gene complement(2803..3450) /gene="" /locus_tag="" /db_xref="4482267..4482914" CDS complement(2803..3450) /gene="" /product="RNA polymerase sigma-H factor (sigma-30)" /translation="MFKNSIVQVTQDFERFNDEELIEMVHQGNTDALDYLITKYRLLV RAKARSYFLIGADKEDIVQEGMIGLYKAIRDFKGDKLASFRAFAELCITRQIITAIKT ATRQKHIPLNSYVSLDKPILDEESDRTLMDVLTGAIMDDPEELIIHREEFGYLEEKMS EILSELELQVLALYLDGRSYHEISAKLNRHVKSIDNALQRVKRKLERHLVLEEMS" gene complement(3519..4031) /gene="" /locus_tag="" /db_xref="4482983..4483495" CDS complement(3519..4031) /gene="" /product="hypothetical protein" /translation="MKNILLVDGYNMIGSWKELRPLRDTNFEDARKRLIELMAEYKAA MGWRVIIVFDAHLVPGVEQSYLESDVEVIYTRKNETADERIEKMTHELKARNVQIHVA TSDMAEQSVIFGNGALRKSARELEIDTSIIQHKISHAVKRKHESRPPSRIELKPDVAI AFEKWRRGLK" gene complement(4034..4786) /gene="" /locus_tag="" /db_xref="4483498..4484250" CDS complement(4034..4786) /gene="" /product="trmH family tRNA/rRNA methyltransferase yacO" /translation="MTEQNGEIIAGKNPVLEALRSGRDMNKVWIAEGVKKSGVNELLD LARERGVIVQFVPKKKVDQLSSANHQGIVASVAAYKYAELEDLFAAAAKKQEDPFFLI LDELEDPHNLGSIMRTADAIGAHGIIIPKRRSVSLTAVVAKSSTGAIEHVPVVRVNNL AQTVDELKERGIWIAGTDAKGSVDYRKMDATLPLAIIIGSEGKGMGRLLKEKCDFLYH LPMVGHVTSLNASVAAALLMYEVYRKRQEANE" gene complement(4792..5205) /gene="" /locus_tag="" /db_xref="4484256..4484669" CDS complement(4792..5205) /gene="" /product="hypothetical protein" /translation="LDKLRNEDVKQLNALALAYMGDAVLEQKIREHLLRSGRVKPNTL HREATRYVSAKAQSMIVHRMMDENYLTEEELAVFRRGRNAKSGSVPKNTDVQTYRNSS GFEAVLGSLYLLNELERVYEIIAYAIQIIEESKGV" gene complement(5211..6611) /gene="" /locus_tag="" /db_xref="4484675..4486075" CDS complement(5211..6611) /gene="" /product="cysteinyl-tRNA synthetase" /translation="MSIQIFNSLSRQKETFVPLEEGKVKMYVCGPTVYNYIHIGNSRP VIVYDTVRRYFQYKGYDVKFVSNFTDVDDKIIKAANELGEEVHELTERFIAAYFEDVT ALGCKKADVHPRVTEHMADIIQFIQVLIEKGYAYESAGDVYYRTRKFNGYGKLSHQSV DDLKIGARIEAGEKKDDALDFALWKAAKPGEIFWESPWGNGRPGWHIECSVMAREHLG DTIDIHAGGQDLTFPHHENEIAQSEAHNDKTFARYWMHNGYINIDNEKMSKSLGNFIL VNDIRKQIDPQVLRFFMLSVHYRHPINFAKDLVEAASAGLERIRTAYNNVKHRLTTTV SLGDHSDEWLNKITEQKAQFEEAMDDDFNTANGISVLFELARIANIYLNETNTCKKVL ETFIETFEVLGDVLGIEFAKEEELLDEEIEALLQERVEARKNRDFARSDEIRDHLQAQ GIILEDTRQGTRWKRG" gene complement(6608..7246) /gene="" /locus_tag="" /db_xref="4486072..4486710" CDS complement(6608..7246) /gene="" /product="Serine acetyltransferase" /translation="MKEDVETIFENDPAARSVLEVVLTYSGLHATWAHRVAHWFFKKR FYFMARAISQISRFFTGIEIHPGAKIGRRFFIDHGMGVVIGETCEIGDNVTLYQGVTL GGTGKEKGKRHPTLEDNVLVATGAKVLGSITIGENSKIGAGSVVLKEVPPNATVVGIP GKIVLKDGVRLEKKLDHQNIPDPVEERCQAFEKQIVILRQEIERLQKERETQ" gene complement(7718..9178) /gene="" /locus_tag="" /db_xref="4487182..4488642" CDS complement(7718..9178) /gene="" /product="glutamyl-tRNA synthetase" /translation="MTKEVRVRYAPSPTGFLHIGGARTALFNYLYAKHHNGKFIVRIE DTDIERNVEGGEASQLDNLKWLGIEYDESIDIGGPYAPYRQMERLDIYKEHAEKLLAQ GAAYKCFCSSEKLEASREEQKARGVAAPTYDGTCRHLSAEEVAAKEAAGEPYTIRMRV PENVTYDFEDLVRGQVTFESKDIGDWVIVKANGIPTYNYAVVLDDHFMEISHVFRGEE HLSNTPKQMMIFDAFGWEYPRFGHMTLIINENRKKLSKRDESIIQFVTQYKDLGYLPE AMFNFFALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPSMFDKQKLTWMNNQYIKKLS LEEVVALSLPHLQKAGLLPDELSAVQHAWATDLIGLYHDQMSFGAEIVELSSLFFKDH IEYDEEAKAVLAGEQVPEVMAAFKAQLEELEEFTPDAVKAAIKAVQKATGHKGKNLFM PIRVVTTGETHGPELPNAICLIGKEKAIDRVEKFAQ" gene complement(9268..9744) /gene="" /locus_tag="" /db_xref="4488732..4489208" CDS complement(9268..9744) /gene="" /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase" /translation="MFRIGQGFDVHAFEEGRPLIIGGITIPHEKGLVGHSDADVLLHT VTDAALGAIGEGDIGRHFPDTDPAFKDADSAKLLEYIWKIVEDKGYILGNVDCTIMAQ RPKMAPYIEQMQNRIAELLHAEPSQVNVKATTTERLGFTGREEGIAAMATILLMKK" gene complement(10088..10783) /gene="" /locus_tag="" /db_xref="4489552..4490247" CDS complement(10088..10783) /gene="" /product="2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase" /translation="MQYEVVLPAAGSGKRMGAGQNKLFLKLLKKPILIHTLEVFQQDP FCTGIWLAVKPEERIYIQELLDEYRITKVKGLPNGGAERQHSVHSCMKEMEQVDIVLV HDAARPFITHAIIANLVQSAHDFGAAIAGVRAKDTMKKVRNGVIEETVDRDSLWMIQT PQAFRFDLIVEAEDVAEKVGFLGTDEAMLVERLGHTVHIVESSYENVKMTTQEDLLFG EAILRKRALQLNE" gene complement(10795..11880) /gene="" /locus_tag="" /db_xref="4490259..4491344" CDS complement(10795..11880) /gene="" /product="hypothetical protein" /translation="VKKFVQIAFLLIGGALGLVFLPPLYELLHLSSNPWLDNPYVSVA LGALLLFTLSFAFSDYFVKLISWMEEVLFKVPVGDLLFGTLGLIIGLIVAYFLGFAIN SVKFPVITEVVPIILSFVLGYLGFRLGFRKRDELIQLFTLRSNQTKKKVAEGNEIQEV RGSYKLLDTSVIIDGRIADISETGFIEGILIVPQFVLTELQHIADSSDTLKRTRGRRG LDILRKLQDERNTNVEITDEDFEDVQEVDLKLVRLAKKMGTDTQIVTNDFNLNKVCEL HHVKVLNINDLANAVKPVVIPGEDMQVVVIKDGKEHNQGVAYLDDGTMIVVEGGRSYI GQAITVTVTSVLQTSAGRMIFAKPKDD" gene complement(12097..13473) /gene="radA" /locus_tag="radA" /db_xref="4491561..4492937" CDS complement(12097..13473) /gene="radA" /product="DNA repair protein radA-like protein (DNA repair protein sms-like protein)" /translation="LAKKKTKFVCSGCGYESAKWMGRCPGCGEWNKMVEEVEVIAKGP RGAFQHSATVTQKAIPIIQVEASEESRVATEMGELNRVLGGGIVPGSLVLIGGDPGIG KSTLLLQVSALLSNKGHRVLYISGEESIRQTKLRAERLGVISQELYIYSETNLEFLNQ TIEEVQPKFVIVDSIQTVFHPEVTSAPGSVSQVRECTAELMRIAKTKGIAIFLVGHVT KEGQIAGPRILEHMVDTVLYFEGERHHNHRILRSQKNRFGSTNEIAIFEMLQGGLKEV LNPSELFLQERSQGAAGSTIVASMEGTRPILVEIQSLVTPTSFNYPKRMATGVDQNRV QLLMAVLEKRMGLMLQAQDAYIKVAGGVKLDEPAIDLAVLTSIVSSFKDQAVRATDCF IGEVGLTGEVRRVSRIEQRVIEAAKLGFKKVFIPASNIGGWDFPQGIEIVGVETIKDA LNACFREL" gene complement(13565..16006) /gene="" /locus_tag="" /db_xref="4493029..4495470" CDS complement(13565..16006) /gene="" /product="negative regulator of genetic competence clpC/mecB" /translation="MFNRFTQRAQKVLQLAQEEAIRWKHESIGTEHILLGLIREGGGI AAKALEAIDISPQMIEAGIEELVGKGKEDVGPIVHYTPRAKKVIELSVDESRKLGHSY IGTEHLLLALIREGEGVAARVLNNAGVGLNKARQQVLLLLGNNDNAQSGQQAAQAANT PTLDSLARDLTQIAREGTLDPVIGRSKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIA EGLAQQIINNEVPEILRDKRVMTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIIL FIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEYRKYIEKDAALERRF QPIQVDEPTVEEAILIIQGLRDRYEAHHRVKITDEAIEAAAKMGDRYISDRFLPDKAI DLIDEAGSKVRLRSFAVPPNLKALEDKLENVRSEKNAAVSGQEFEKAAALRDTEQKLK DEIEATRKNWKEEQGKAESKVTVDDVAAVVSMWTGIPVAKIASEESSKLLQLEEELHK RVVGQGEAVEAISRAIRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAEVMFGDE DAMIRVDMSEYMEKHSTSRLVGSPPGYVGFDDGGQLTEKVRRKPYSVVLLDEIEKAHP DVFNILLQVLEDGRLTDSKGRVVDFRNTVVIMTSNVGADALKYQKSLGFNVGGADSKH KDMKSTMLEELKKAFRPEFLNRIDEMIVFHSLEKEHLKEIIAMMGNALTKRLKEQDIS LELTDAALEKIAQEGYDPQYGARPLRRALQKQVEDRLSEELLKGNVEKGNHVIIDYVN DEFIVKKKEGVSISK" gene complement(15999..17108) /gene="" /locus_tag="" /db_xref="4495463..4496572" CDS complement(15999..17108) /gene="" /product="putative ATP:guanido phosphotransferase" /translation="MMIESFLERATPTWMRIEDDYSDIVISTRIRLARNLDGYRFPLS FSENEALQVEQAVTHAVSDSPTLQNDYAYFSINDLTPLQRQILVEKHLISPQLAKKEQ VGSVLLSQDESVSIMVNEEDHLRIQCMTASFQLQNAYEQANKIDRILEKVLPYAFRDT FGYLTSCPTNIGTGLRASVMMHLPALTLTGQMNQIINAMTRLGMTVRGIYGEGSENLG NVYQVSNQITLGKTEEDILADIQSVAEKIIQKERHARGRLMEKAELALEDRVYRALGT LTYARILTSEEAATCLSNVRLGVDLQLIDGILATTLNECVVSMQPGFLQHYAGEALPP AERDRVRAEMLREALIQTHTNKPNNGEKGEDLYDV" gene complement(17105..17653) /gene="" /locus_tag="" /db_xref="4496569..4497117" CDS complement(17105..17653) /gene="" /product="hypothetical protein" /translation="MEMICEHCKQRNATVTVTQVQNGQKVEHHYCDVCASQFHPFHAE FKQEPVSIQQLLSNWFGSPTWQKVGEKQQTQPQQQTCPQCEFTYKQFLKEGKFGCPSC YDTFSEHLPKLFNRIQAGPQHIGKMPGAHSNVYVIKKQIEEIRKRMKFAVDEEQFEEA AKLRDEVKELEKQLQFEGGDVS" gene complement(17661..18158) /gene="ctsR" /locus_tag="ctsR" /db_xref="4497125..4497622" CDS complement(17661..18158) /gene="ctsR" /product="transcriptional regulator" /translation="VKQARCIPKMRNISDIIEGYLKQVLELGGEGHIEIKRSEIADKF QCVPSQINYVINTRFTAERGYLVESKRGGGGYIRILRVRANSQIDLIDDVLRHIEGGA SQTMAEDLVYRLIDEQVISKREAKLMLAAIDRSTIDLHLPLRDIIRAKILRAMLTTIK YEQQK" gene complement(18399..18605) /gene="" /locus_tag="" /db_xref="4497863..4498069" CDS complement(18399..18605) /gene="" /product="hypothetical protein" /translation="VKAISIQAILFQLVMAVLLAVSGVLSFFIIGIPFLIVFGIMLFV VPIIGIVKALTDEPWRYPIVGRWV" ORIGIN 1 ttattttact actacgttag cagcgtcaat tttaacagct ggacccattg tagttgtaat 61 atttacagat ttcatgtaag tacctttagc tgcagcaggt ttcgcttttt gaactacatc 121 aaatacagct aagaagtttt ctactaattt tgctgcagag aaagaaactt taccgatagg 181 agcgtggatg ataccagctt tatcagcacg gtattctact ttaccagctt tgatttcttc 241 gatagctttt gttacatcga aagtaactgt accagtttta gggtttggca ttaagccttt 301 aggtcctaat acacgaccaa gtttacccac ttcacccatc atgtcaggag ttgctacgat 361 tacatcgaaa tcaaaccaac cttgttggat tttttggatg tactctgcat cacctacata 421 atcagcacca gctgcttctg cttctttaag tttttcacct ttcgcgaata ctaatacgcg 481 ttgagtttta ccagtaccgt ttggtagtac tactgcacca cggatttgtt ggtcgttttt 541 acgagtatca atacctaagc ggaaagcaac ttctacagta gcgtcgaagt ttactgtgct 601 agttttttga gcaagttcga ttgcttcttg tgcactgtat agtgagttac gatcaattaa 661 tttagctgca tcttgcagtt ttttaccttt tttagccatt atatatttcc tccttgattg 721 tggttataac ggattttacc tcccacgaat aaaggttgcg tgttcacaaa gaaacttcgc 781 aaccttccaa aaaacaaaac atcaagtaac tgggattagt cttcgataac aatacccatg 841 cttcgtgcag taccttctac cattaacata gcagcttcta ctgaagcagc gttaaggtct 901 ggcattttag tttcagcgat ttcgcgaact ttatcacgtt taaccgttgc cactttttta 961 cgatttggtt caccagatcc agattggata ccagctgcta ctttaagtag aactgctgca 1021 ggtggagttt ttgtaatgaa agtgaaagaa cgatcctcga atactgaaat ttcaactgga 1081 ataataagac cagcttgatc agcagtacgc gcgttgaatt ctttacagaa tcccatgatg 1141 ttcacacctg cttgacctaa tgcaggacca accggtggag ctggattagc tttaccagca 1201 gggatttgaa gttttacaac tttaataact tttttagcca cgagacacac ctccttaagt 1261 ccgtgatgtg gtaattgggt tgcccctccc actcaatatc tgtctgtcag ctaagtgccg 1321 ataacattaa aattatcatt acagacgtca aacaaaagta tgacagtctg acctatgaaa 1381 tgataccact tttaattttt ttaagcaagt agtaattaac aaaatctgcg aaacgtctac 1441 caattggcat gtcacagttc tagaaattgt actataattt ttgaatttgt tcgaagatct 1501 agactccata cattgtttcg cgaccaaaca tatcaactga cacttttatt tttccttttt 1561 ctgtgtcaat ttcttcaaca cgtccttgga aatgagcgaa cggcccttct aatacttcaa 1621 ctgcctcacc aatagagatg tccacttcaa caatcttatc agtcataccc atttgttgta 1681 atagacgatc cgcttcttca ggtagtaaag gtgttggttt tgctcctcca ccagaggacc 1741 cgataaagcc tgttacaccc ggcgtattac gcactacata ccaagaatca tctgtcataa 1801 taagctctac taatacataa cctgggaaaa ctttacgcat catcgtacgc tttttcccat 1861 tccttcattt ctgtttcctc atgctcagga acaatcactc ggaagatttt atcttgcatt 1921 cccattgttt ctacacgttt tttctaggtt tgcttttact cggttctcat accctgaata 1981 cgtatgaaca acataccaat ttttctccat aactactagg actcctcgtc cgtccctccc 2041 ttacaaataa aagtgaaaat gaatcgcgat atgctagatg caatccttac ccttttcaca 2101 aacatctcat ataaacatag ccttttccta taaagaaagc ctgaagatat gtatcgaaac 2161 tagcatagtc atctatcgct actatcatac ttatcataat gagattaact tactgccatt 2221 cacttcatcc atatcacttg cacataaaga tagaattacc tgctgaatga agataaaaca 2281 aacgaaaaaa cccgttattg caatggacgg gctatttcat aagtattaac atgctattta 2341 ctaaattata aatctaagta ccagcggaat aatgatgaaa tacctaagtc aactaacaca 2401 aaaaataaag ccataacgac aacagttgaa attacaacga ctgtatattt agtcagctct 2461 ttacttttcg gccagcttgt tttgcgcatt tctgacatta catcactgaa aaagcctttg 2521 atcttgccca ttctagctta acctccgaat caatcaaaat ctgtctattt acatatcatt 2581 ttataacgtt tgtttatgca ctgtatgttc attgcaatgc gagcaaaatt tctttaattc 2641 gaggcgtaca gtggagcctt ctttagccgg gaacgtgtaa tttctcgatc cacatttctc 2701 gcaatttagc acgacttttt ttgccataca ctcacctttt tcggcacttt atctttttaa 2761 gactaacacc tatatttgtc aatgtcaata aagcctatga cctctaagac atttcctcaa 2821 ggactaaatg tcgctctaat ttgcgcttca cccgctgcaa agcattatca atggatttca 2881 catgacgatt taattttgca gaaatttcat gatatgatcg gccatctaga tatagagcta 2941 aaacctgtaa ctctagttca cttaaaatct cactcatctt ttcttctaaa tatccaaatt 3001 cttctctatg aattattaat tcttctggat catccatgat agcgcctgtt aaaacatcca 3061 ttagcgttcg gtctgattct tcatctaaaa tgggcttgtc caaagaaaca taggagttga 3121 gaggtatatg cttttgccta gtagccgttt taatagcggt aataatttgc cttgtaatac 3181 atagctcagc aaatgcccgg aaagaagcaa gcttatcccc tttaaaatca cgaatcgctt 3241 tatacaaacc aatcatgccc tcttgcacaa tatcttcctt atcagcacca attaagaaat 3301 aggatcttgc cttcgcccta actaacaaac ggtatttcgt aattaaataa tccaacgcat 3361 ctgtattacc ttgatgcacc atttcaataa gctcttcatc attgaatcgt tcaaaatctt 3421 gtgtcacttg tacaatgcta tttttaaaca tggtatcacc tcagccacaa cagataatta 3481 ggaacagtat aacggaaatg gaaaatatgc gtcaatcaat catttcaatc cacgtctcca 3541 tttttcgaat gctatcgcca catccggctt taattctata cgtgaaggtg gtctactttc 3601 atgtttcctt tttacagcat gagatatttt atgctggata atgcttgtat ctatttctag 3661 ttctctcgct gattttctca aagctccatt accaaagatc acactttgct ctgccatatc 3721 ggaagttgct acgtgtattt gtacatttct agccttaagt tcatgcgtca ttttttcaat 3781 acgttcatct gctgtttcat ttttccgagt ataaatgact tcaacatcac tttctaaata 3841 agattgctct acgcctggta ctagatgtgc gtcaaaaaca ataattacgc gccaccccat 3901 agctgcttta tattcagcca taagttctat caaccttttg cgagcatcct caaaatttgt 3961 atcccgcaat ggtcgaagct ctttccagga cccaatcata ttatagccat caactagcaa 4021 aatgtttttc attgttactc attcgcttct tgacgcttac gatacacttc gtacattaat 4081 aatgctgctg ccactgaagc attcagtgat gtcacatgcc ctaccatcgg taaatgatac 4141 aagaagtcac atttctcttt taataagcga cccattccct taccctcact accgataatg 4201 atagccaatg gtaatgttgc atccattttc cgatagtcta cagagccctt cgcgtctgta 4261 ccagcaatcc atatacctcg ttcttttagt tcatccactg tttgagccag attgtttaca 4321 cgtactacag ggacatgttc aatagcgcct gttgaagact tcgccacgac agctgttaaa 4381 cttactgaac ggcgctttgg aataataata ccatgcgctc ctattgcatc agctgttctc 4441 ataatagaac ctaggttatg tggatcttca agctcgtcta agattaagaa aaagggatct 4501 tcttgttttt ttgcggctgc agcaaataaa tcctccagtt cagcatactt atatgctgca 4561 acagaagcaa caataccttg atgatttgca cttgataatt ggtcgacctt ctttttcgga 4621 acaaactgaa cgatcactcc acgttctcga gctagatcta gcagttcatt gacacccgat 4681 ttttttaccc cctctgcaat ccatacttta ttcatatcgc gtcctgaacg aagtgcttct 4741 aacactgggt ttttaccggc aataatttct ccattttgtt ctgtcattct ttctacactc 4801 ctttcgattc ctcgattatt tgaatagcat atgcaatgat ttcatacacg cgttcaagtt 4861 catttaataa atataaacta ccaagtaccg cctcaaagcc agagctattt cgataagttt 4921 ggacatctgt attctttggt acagagccgg acttggcatt acgtccacga cggaacactg 4981 ccaactcctc ctctgttaaa taattctcat ccatcatacg atgaacaatc atagattgtg 5041 cctttgccga aacgtaacgc gttgcctctc gatgaagtgt attcggttta actcgacctg 5101 aacgaagcaa gtgttctcgt atcttttgct ccaatacggc gtcacccata taggctaacg 5161 ccaacgcatt taattgctta acatcttcat tgcgaagttt atccaactta attaccctcg 5221 tttccatcta gttccttgtc gcgtatcttc taaaatgata ccttgggctt gcaaatggtc 5281 acgaatctca tcagaacgag caaaatcacg attcttacgt gcctctacac gctcttgtag 5341 tagtgcttca atttcttcgt ctaataattc ttcttctttt gcaaattcga tacctaagac 5401 gtcacctagt acttcaaaag tttcaataaa tgtttctaac acttttttgc aagtattcgt 5461 ttcatttaaa taaatattag caatacgagc taactcaaat aataccgaaa tcccgttagc 5521 tgtattaaaa tcatcatcca tggcctcttc aaactgtgcc ttttgctcag taattttatt 5581 cagccactca tctgagtgat cgcctaagct tacagtagtc gtaagacgat gcttcacatt 5641 gttgtaggct gtacgaatgc gctctaagcc agctgaagct gcctctacta aatccttcgc 5701 aaaattaatt ggatgacgat aatgaacaga tagcataaag aagcgaagca cctgtggatc 5761 aatttgttta cgaatatcat tcaccaaaat aaaattccca agagatttag acatcttttc 5821 attatcaata ttaatataac cattatgcat ccaataacgt gcaaatgttt tatcattgtg 5881 agcttctgac tgtgcaattt cattttcgtg gtgtgggaaa gttaaatcct gcccaccagc 5941 gtgaatatca atagtatctc ctaaatgctc acgagccatt actgaacatt caatatgcca 6001 accaggacga ccattgcccc aaggactttc ccagaaaatt tcacctggct tcgctgcttt 6061 ccataaagca aaatctaatg catcatcttt tttctcacca gcttctatac gtgcaccaat 6121 ttttaaatca tctacggatt gatgtgataa tttaccatag ccattaaact tgcgcgtgcg 6181 gtaatacaca tcacctgctg actcataagc atagcctttt tcaattaaaa cttggataaa 6241 ttgaataata tcagccatat gctctgttac acgtggatga acatcggctt ttttgcaccc 6301 taatgcagta acatcttcaa agtacgcagc tataaagcgc tctgttaact catgaacttc 6361 ttcaccaagc tcattggcag ccttaataat tttatcgtct acatccgtaa aattggaaac 6421 aaactttaca tcatagcctt tatattggaa atagcgacgg actgtgtcgt aaactataac 6481 aggacgtgaa ttcccgatat ggatatagtt ataaacggta ggcccgcaga catacatttt 6541 tactttgcct tcttctagcg gaacaaaggt ttctttttgt cttgataatg agttgaaaat 6601 ttgaatactc attgtgtctc tctctccttt tgtaagcgtt caatttcctg tcttaatata 6661 acaatttgct tctcaaaagc ttgacaacgt tcttctacag gatcaggaat attttgatga 6721 tctagttttt tctctagacg aactccatct ttaagtacta ttttaccagg tataccgacc 6781 acagtggcat ttggaggcac ctcttttaaa acaactgacc ccgcaccaat tttactattc 6841 tcgccaattg taatagaacc taaaacttta gcgcctgttg ctacaaggac attatcctct 6901 aatgtagggt gtcgttttcc tttttctttc cctgtaccac ctagagttac cccctggtac 6961 aaagtcacat tatcaccgat ttcacatgtt tcaccaatca caacacccat accatggtct 7021 ataaaaaagc ggcggccgat tttcgcacca ggatgaattt caataccagt aaaaaagcgg 7081 cttatttgtg aaatggcacg agccataaaa taaaagcgtt ttttaaagaa ccaatgagcc 7141 actcgatgag cccatgtggc atgcaaaccg gaatatgtta ataccacttc caatacactt 7201 cgcgcagctg gatcattctc aaaaattgtt tccacatctt ctttcatcct tttaaacaca 7261 aaaaactccc cctttttatg ttgttcttgc tcaaattcct agaaaccctt tacacagaac 7321 cgacactgtc gtcaactttc tttagaattc tctgcctaag atgatgtggt atgtttgttt 7381 gaatgcctcc ctcttcatca aagaatgaag ataaaataaa aaacgcccct atcatcccaa 7441 aaaggaatga cagagacgct taaatttgcg tggttccact ctgattgaag gcaaaaagcc 7501 tcccactctg gtcgttcttt aacgagaacg aatcgataaa gcctactata gttcagcttt 7561 atgctcaaag gtgcatttca gttttgccta gactcagacc actttcagcc ggtgatggtc 7621 ctctctttag agcgtgcgcc acttacttct ccttatcaac gctttttcaa tgtaaataca 7681 ttttacaacg caagaatcaa ttgtcaatgg atttctattt attgcgcaaa tttttctaca 7741 cgatcaattg ctttctcttt gccaattaag cagatagcat tgggaagctc cggtccatgt 7801 gtttcacccg ttgtgacaac acggattggc ataaataaat ttttaccttt atgacctgtt 7861 gccttttgca cagctttaat agctgctttt accgcatctg gcgtaaattc ttctaattct 7921 tcgagctgtg ctttgaatgc agccattacc tctggtactt gctctcctgc taaaacagct 7981 ttggcttctt catcatattc aatatggtct ttaaagaata ggctagataa ttcaacaatc 8041 tctgcaccaa agctcatttg gtcatggtaa agcccaatta aatctgttgc ccatgcatgt 8101 tgcactgctg aaagttcatc tggtaaaagt ccagcttttt gtaaatgtgg taatgataaa 8161 gctactactt cttctaaaga tagtttttta atatattgat tattcatcca tgtcaacttt 8221 tgtttatcga acatagatgg tgatttagaa agacgttttt catcaaagat cttgataaat 8281 tcttctttag agaaaatttc ctcttcccct tctggagacc agccaagtaa agcaaagaag 8341 ttgaacattg cttcaggaag ataccctaaa tccttatatt gagtgacaaa ttgaataatg 8401 gactcatcac gttttgatag ctttttacgg ttctcattaa taattaacgt catatgaccg 8461 aagcgcggat actcccaacc aaatgcatca aagatcatca tttgttttgg cgtattagat 8521 aaatgctctt caccacggaa aacgtgagaa atctccatga agtgatcatc tagaactaca 8581 gcatagttat acgttggaat accgtttgct tttacaatta cccagtcgcc aatgtcttta 8641 gattcaaatg taacttgtcc acgaactaaa tcttcaaaat catatgttac attttctggt 8701 acacgcatac gaattgtgta tggctcaccc gctgcttctt tagctgcaac ttcctcagct 8761 gagagatgac ggcatgtacc atcataagta ggagctgcta cacctcttgc tttttgttcc 8821 tcacgagatg cttccagttt ttctgaagaa cagaagcatt tgtaggctgc accttgcgct 8881 aatagttttt cagcgtgctc tttataaata tcaagacgct ccatttgacg ataaggcgca 8941 taaggtccac caatatcaat ggactcatca tattcaatac ctaaccattt taggttatct 9001 aactgagatg cttctccacc ctctacatta cgttcaatat ccgtatcttc aatacgtaca 9061 atgaatttac cgttatgatg ttttgcatat aaataattga ataatgctgt acgcgcccca 9121 ccgatatgta aaaaacctgt tggagatggc gcgtaacgaa cgcgaacttc tttcgtcata 9181 ttaaaagcct cctaaatttt cgatcaaaaa ttgactttgt tcattttacc actctgtaac 9241 tggaaataaa agcagagttc actcacattt atttcttcat caaaagaatt gttgccatcg 9301 ctgctatacc ttcttcacgt ccagtaaaac ctagacgttc agttgttgtc gctttgacat 9361 ttacctgtga cggctcagca tgtaacaatt ctgcaatacg attttgcatt tgctcaatat 9421 atggtgccat ttttggtcgt tgagccataa ttgtacaatc gacattacct agaatatatc 9481 ctttatcctc aacaattttc caaatgtatt ctaataattt tgctgaatct gcgtctttaa 9541 aagctggatc tgtgtctgga aaatgacgtc caatatctcc ttctccaatt gctcctagcg 9601 ctgcatctgt aactgtgtgt aataatacat ctgcatctga gtgtccaact aacccttttt 9661 catgtggaat agtaatacca ccgataatta acggacgccc ttcttcaaat gcatgtacat 9721 caaaaccttg tccaattcga aacatatgat agagagacta cgttagccat acatatggat 9781 aattctccta gtttgcctaa aatgcagtct cattcacctt ccttcacttt tatctattta 9841 gtcactatta taccctcaca ttttaacata tttcctagga aattgagctg atagcaaata 9901 gtcagcattt tcttatacca acagatccat tactccttgg tgtgctggct tatagttttt 9961 ccaagctaac caatcattat tacaacaggc gttaggacga ccactgaaaa ataaacatgt 10021 cccattctta ggcatcaata taaaatccca ttagcaacct atcactaatg agatttttaa 10081 actagtcact attcatttaa ttgcaatgct cgttttcgta aaatagcttc tccaaatagc 10141 aaatcctctt gtgtcgtcat ttttacattc tcgtagctgc tttccacaat atgcactgtg 10201 tgaccaagac gctcaactag cattgcttca tcggtaccaa gaaaacctac tttttcagca 10261 acatcctctg cctcaacaat taagtcaaaa cggaaggctt gaggcgtttg aatcatccat 10321 aagctgtcgc gatctactgt ttcctcaatg acaccattac gaactttttt cattgtgtcc 10381 tttgctcgga cacctgcaat ggctgcacca aagtcgtggg cactttgcac aagattggcg 10441 ataatagcat gtgtaataaa aggtcttgcc gcatcatgaa caagcacgat gtctacctgt 10501 tccatttcct tcatacatga atgtacagaa tgctgtcgtt cagcaccacc attaggtaaa 10561 cctttgactt tcgtaatacg atattcatcg agcaattctt gtatataaat acgctcctct 10621 ggttttactg ctagccaaat acctgtgcaa aaagggtcct gttgaaagac ctctaacgtg 10681 tgtatcagga taggcttctt taaaagtttt aaaaacaatt tattttgtcc tgcccccata 10741 cgttttccac ttcctgcggc aggtaaaact acttcatact gcatgttttc acttcctaat 10801 cgtccttcgg ctttgcaaat atcatacgac ctgctgacgt ctgcagcaca ctcgttactg 10861 ttaccgttat tgcctgtcct atatagctac gaccgccttc cacaacaatc attgtaccat 10921 cgtctaaata ggctactcct tgattatgct ctttgccatc tttaatgact accacctgca 10981 tatcttcacc tggaataacg acaggcttta cggcattcgc taaatcattt atatttaata 11041 cttttacatg atgtagctcg catactttat taaggttaaa atcatttgtg acaatttgtg 11101 tatcagtccc catttttttt gccagtcgta caagttttaa atctacctct tgcacatcct 11161 caaaatcctc atctgtaatc tctacgttcg tattacgttc atcctgtaat ttccttaaaa 11221 tatctaagcc tcgacgacct cttgtgcgct ttaatgtatc tgaggaatca gcaatatgct 11281 gaagctctgt taggacaaat tgaggcacaa ttaagattcc ttcaatgaat cctgtttcag 11341 aaatatcagc gatgcggcca tcaataatga cacttgtatc taacaatttg taacttcctc 11401 gcacctcttg aatttcatta ccctcagcaa cttttttctt tgtctgatta ctacgtaagg 11461 taaaaagctg gattaattca tccctttttc taaaacctaa acggaagcct agatatccta 11521 atacgaatga caggataata gggactacct ctgtaataac agggaacttc acactattaa 11581 tagcaaagcc taaaaaatac gctacaatta gccctattat taggccaagc gtaccaaata 11641 acaaatctcc gaccggaacc ttaaacagga cctcttccat ccagctaatg agcttcacaa 11701 aataatcgga aaacgcgaat gacaatgtaa acagtaaaag cgctcctaat gctactgata 11761 cgtaaggatt atcaagccaa ggattagatg ataaatgaag caattcgtat aatggcggta 11821 agaaaacaag gcccaatgct cctccaatca gtaaaaaagc tatctgaaca aattttttca 11881 caagctgtca cctcctattg ttagttaaga ttatacatag tttattatag aaaatccttc 11941 ttcagcccat cagattatca ttatttaact ctctctttcc aaccacacat tcaccctgca 12001 ttaactagga cgcctattcc tttacttgag tttcccactt tttacgtcaa aatgaaggaa 12061 atgcatgtca gaatagtatc taacatgcat ggttttccta taactctcta aaacaggcat 12121 ttaatgcatc ctttattgtt tctacaccga caatttcaat cccttgcgga aaatcccaac 12181 cacctatatt tgatgcagga atgaagactt ttttaaaacc aagcttcgcc gcttcaatga 12241 cacgctgctc gatacgggat actcgacgta cctctcctgt cagacccact tcaccaataa 12301 agcaatcggt tgcccttaca gcctgatcct taaagctaga cacgatgctt gtcagaacag 12361 ctaaatctat agcaggttcg tccaatttca caccaccagc aactttaata tatgcatcct 12421 gtgcttgtag catgagaccc atacgctttt caagcacagc catcagcaat tgcactctat 12481 tttgatctac cccggttgcc atccgtttag ggtaattaaa gcttgtaggc gtcactagcg 12541 actgaatttc aacgagtatt ggccttgttc cctccatcga ggcaacaatc gtggaacccg 12601 cagccccttg tgaacgctcc tgcaaaaata gctcagatgg gttcagcacc tcttttaaac 12661 caccctgtag catttcaaat atagcaattt cattggtaga gccaaagcgg tttttttgac 12721 ttcgtaaaat acgatgatta tgatgtcttt cgccttcaaa atataggact gtatccacca 12781 tatgttctaa aattcgaggc cctgcgattt gcccctcttt cgtaacatgc ccaactaaga 12841 atatagcaat cccttttgtt ttagctattc gcataagctc agctgtacac tcacgtacct 12901 gagatacact acctggcgca cttgttacct ctggatgaaa gaccgtttgt atggaatcaa 12961 caatgacaaa tttcggctgt acttcctcaa tcgtttgatt caaaaactca agattcgttt 13021 cggaataaat gtacagctct tgagagatta cccctaaacg ctctgctcgt agcttcgttt 13081 gacgaataga ctcctcacct gaaatataca gcacgcgatg gcctttattt gagagcaaag 13141 ctgaaacttg tagtaataat gttgatttcc caatcccagg atcgccacct attaatacta 13201 gagagccagg cacaatacca ccgcctaata cacgattcag ctcgcccatt tctgtcgcca 13261 ctcgagactc ttcactagct tcgacctgaa taatggggat tgccttttga gtaactgtag 13321 cagaatgctg gaatgcccct cttggtcctt tcgctataac ttctacttcc tccaccattt 13381 tattccattc tccacagcct ggacatcttc ccatccattt tgccgattca tagccacagc 13441 ctgaacatac aaatttcgtt tttttctttg ccaactttct ttcacctcga atatttgttc 13501 ttatattaat tgtacaaaaa aaaagacagc ttggcactta atgccttact gtctttagtt 13561 tgaaattatt tagagataga aactccctct tttttcttca caataaactc gtcatttaca 13621 taatcaatga taacatgatt acccttctcc acattaccct ttaataattc ttctgataat 13681 cggtcttcca cttgtttttg taatgctcga cgtagtggac gtgcaccgta ttgagggtcg 13741 tagccctcct gagcaatttt ttcaagcgct gcatctgtta attctaatga aatatcctgt 13801 tctttcaacc gctttgttag agcgttcccc atcatcgcaa tgatttcttt taaatgctct 13861 ttttctaatg aatggaacac aatcatttca tcaatacggt ttaagaattc tggacggaat 13921 gcttttttca attcttcgag catcgtactc ttcatatctt tatgtttaga atctgcacca 13981 cctacgttaa aaccaaggct tttttgatat ttaagagcat ccgcgccgac gttagaagtc 14041 attatcacta ctgtgttgcg gaagtctact acacgcccct tagagtccgt taatcgacca 14101 tcttcaagaa cttgcaggag aatattgaaa acatcagggt gtgctttttc aatttcatct 14161 agtaatacaa cagaatatgg tttacgacga accttttcag tcaattgacc accatcatca 14221 aagcctacgt agcctggagg tgaacctact aaacgagaag ttgaatgttt ctccatgtac 14281 tcagacatat cgacacgaat catagcatct tcgtcaccaa acatcacttc agcaagtgct 14341 cttgcaagct ccgttttacc aacaccagta ggacctaaga aaataaatga accgattggt 14401 cgttttggat ctttgaggcc cgctcttgca cgacggatcg cacgggaaat ggcttctact 14461 gcttcccctt gcccaaccac acgtttgtgt agctcttctt caagttgtaa taattttgaa 14521 gattcttcag aagcaatttt agctacagga attcctgtcc acattgatac aactgctgca 14581 acatcatcta ctgttacttt ggactcggct ttaccttgct cttctttcca attttttctt 14641 gtagcttcaa tctcatcttt aagcttttgc tccgtatctc ttaacgcagc agccttttca 14701 aactcttgac ctgatacagc agcattcttt tcagagcgaa cattttcaag cttatcttca 14761 agtgccttta agtttggtgg cactgcgaat gaacgtaagc gaacctttga tcctgcttca 14821 tcaatcaggt caattgcttt atctggtaag aagcggtcag aaatatatcg atcacccatt 14881 tttgccgctg cttcaattgc ttcatctgta attttcactc ggtgatgtgc ttcatagcga 14941 tctcgtaagc cttgaataat gagaattgct tcttccaccg ttggttcatc cacttggatc 15001 ggttggaaac gacgctctaa tgctgcatct ttttcaatat atttacgata ttcatcaagc 15061 gttgtcgcac cgatacattg cagctcacca cgcgctaagg atggttttaa aatatttgat 15121 gcgtcaattg caccttctgc accacctgca ccgattaaag tgtgtaattc atcaataaat 15181 aaaatgatat ttccggcttg gcggatttca tccattactt ttttcaaacg gtcctcaaat 15241 tccccacgat attttgtgcc tgcaacgaca gttcccatat ctagtgtcat cacacgtttg 15301 tctcgaagaa tttctggtac ttcattatta ataatttgct gtgctaaccc ttcagcaatt 15361 gctgttttac caacacctgg ctcaccaatt aaaacagggt tattttttgt acgacgcgat 15421 aacacttcga taacacgtgt aatttccttg cttcgaccaa tcacaggatc taacgtgcct 15481 tcacgggcaa tttgagttaa atcacgggct aaactatcta atgtaggggt attcgcagct 15541 tgtgccgctt gttgacctga ttgcgcatta tcattattcc ctaataacaa taatacttgc 15601 tgacgtgctt tatttaagcc cacacctgca ttgtttaaga cgcgagctgc tacaccttca 15661 ccttcacgta taagggctaa cagcaaatgc tctgtaccga tatacgaatg gcctaattta 15721 cgagattcat caaccgatag ttcaattact tttttcgctc gtggcgtata gtgaacgatt 15781 ggaccaacat cttctttacc tttaccaact aattcttcaa taccagcttc aatcatttga 15841 ggactaatat caatagcttc taacgctttt gcagcaatac cgccgccttc acgtataagc 15901 cctaataaaa tgtgctctgt gccaatggat tcgtgcttcc aacgaatagc ctcttcctga 15961 gcaagctgta atactttttg cgcgcgttgt gtaaaacgat taaacatcat ataaatcctc 16021 tcctttttcc ccattattag gcttattcgt gtgtgtttga attaatgcct cacgaagcat 16081 ttctgctcgt acacgatcac gttcagcagg cggtaatgcc tcacctgcat aatgctgtaa 16141 aaaacctggt tgcatactga cgacgcactc atttaaagtt gttgcgagta taccgtcaat 16201 caactgtagg tcgactccta aacgaacatt cgaaagacag gtagccgctt cctcacttgt 16261 taaaattctt gcataagtaa gggtacctaa agctcgataa actcgatctt ctaaagcaag 16321 ctcagctttt tccatcagcc tacctctcgc atgccgttcc ttttgtataa ttttttcagc 16381 aacactttgt atatctgcta aaatatcttc ttctgtcttt ccaagtgtaa tttggttaga 16441 cacttgataa acgttcccta aattttcgct tccttcacca tatatacctc ttaccgtcat 16501 gcctaagcgt gtcatcgcat ttataatttg attcatctgt ccggttaacg taagagcagg 16561 tagatgcatc atcacagatg cccgaagccc agtaccaata ttcgtaggac agcttgttaa 16621 atagccaaag gtatctcgaa atgcataagg taagaccttc tctagaatac ggtcaatctt 16681 attcgcttgt tcataggcat tttgaagctg aaaactcgcg gtcatacatt gaatgcgcaa 16741 gtgatcctct tcattcacca taatactcac cgattcatct tgtgacagaa gcacagagcc 16801 cacctgctct ttttttgcaa gctgcggact aatcaaatgc ttttctacaa gaatttgacg 16861 ttgtaaaggt gttaaatcat tgatagaaaa ataagcataa tcattttgaa gcgttggact 16921 atcgcttact gcatgtgtaa ctgcctgttc cacctgtaaa gcctcgttct ctgaaaacga 16981 taatggaaaa cgatatccat ctaaatttcg agcaaggcga atacgtgtac taatgacaat 17041 gtcagaataa tcgtcttcaa tacgcatcca agtaggtgta gcacgctcta aaaacgattc 17101 aatcatcatg acacatcacc accttcaaat tgtagctgct tctcaagctc tttgacttca 17161 tcacgaagct ttgctgcctc ttcgaattgt tcttcatcta cagcgaactt catacgttta 17221 cggatttcct caatttgctt tttaatgaca tacacattgc tatgggcacc tggcatttta 17281 ccaatatgtt ggggaccagc ctgtatccga ttaaagagct taggtaaatg ttcgctaaaa 17341 gtgtcataac agcttgggca accaaactta ccttctttca aaaattgctt atacgtaaat 17401 tcacattgtg gacacgtttg ctgttgtggc tgtgtttgtt gtttttcccc caccttttgc 17461 catgtaggtg agccaaacca gttagataat aactgttgta tagaaactgg ctcttgttta 17521 aactctgcat gaaatggatg gaactgtgag gcgcagacgt cacaataatg gtgctccacc 17581 ttttgcccat tttgaacttg tgttacagta actgtcgcat tacgttgttt acaatgttca 17641 catatcattt ccatcacctc actatttctg ctgctcgtat tttatagttg tcagcatcgc 17701 ccgcaatatt tttgctcgaa ttatatctct taaaggaaga tgtaagtcga ttgttgagcg 17761 atcaattgct gctaacatta acttcgcttc tcgctttgaa attacctgct cgtcgatgag 17821 tcgatacact aaatcttctg ccattgtttg cgatgctcca ccttcaatat gccggagaac 17881 atcgtcaatt aaatcaatct gtgaattcgc gcggacacgt aaaattcgaa tgtatccacc 17941 accaccacgc ttgctctcta caaggtaacc tcgctcggca gtaaatcttg tattaatgac 18001 ataatttatt tgtgacggaa cacattgaaa tttatctgca atttcactac gttttatttc 18061 aatatgccct tccccaccta attcaagtac ttgctttaag taaccttcta tgatgtctga 18121 tatattacgc attttaggaa tacacctcgc ttgcttcact gactttgact atctttgact 18181 ttctttgagt atattataca aaacgcttga aaataattgc aatgatttcg cccagagaaa 18241 aatgaaatgc cttaaaaagt atattcaagc gtaaaaaata gcacttatta attaatggct 18301 atcgagcaca tttatttgct tcctacacct aatgtaccct ttttatccat agaaaaaacg 18361 caagcatatg caactagcat atacttgcgt ctataaaaat tatacccaac gacctacaat 18421 tggataacgc caaggctcat cagttaatgc tttgacgata ccgataattg gtactacaaa 18481 aagcataata ccgaaaacga ttaaaaatgg aatgccaatg atgaaaaagc ttaagactcc 18541 agagacagca agtaaaaccg ccatgacaag ttggaaaagt attgcttgga tagaaattgc 18601 cttcacttcc tcatccgtac taattaaaaa gaagat //