LOCUS NC_009699:4 25515 bp DNA linear BCT 03-SEP-2013 DEFINITION Clostridium botulinum F str. Langeland chromosome, complete genome. ACCESSION NC_009699 SOURCE Clostridium botulinum F str. Langeland chromosome, complete genome. COMMENT locus start: 490652; locus end: 516166 COMMENT n1_4mer:GRV/n1_4mer:RV = 4.623520; n0_4mer:D = 22.051313; n0_4mer:PS = 42.123482 FEATURES Location/Qualifiers source 1..25515 /organism="Clostridium botulinum F str. Langeland chromosome, complete genome." gene 1..2601 /gene="clpB" /locus_tag="clpB" /db_xref="490652..493252" CDS 1..2601 /gene="clpB" /product="clpB protein" /translation="MDIEKLTLKVQQAINDSQLVAVKYNHQQIDTIHLFSALISQDDG LIPNILGKMGVNIRDINAETNRVLDSMPKVLGEGAQSSSVYPTRRFEEVLVKAESIAK DFKDSYISVEHVLLAVMDVDRNTVLPILEKFGVKKSEFLKALSAVRGSQRVDNQDPEG TYEALVKYGRNLVEEAKKHKLDPVIGRDEEIRRVVRILSRRTKNNPVLIGEPGVGKTA IVEGLAERIVRGDVPESLKNKIIFSLDMGALIAGAKYRGEFEERLKAVLKEVQNSEGR IILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELHCIGATTFDEYRQYIEKDKALE RRFQPVITDEPTVEDTVSILRGLKERFEIYHGIRIHDSAIVAAAKLSSRYITDRYLPD KAIDLIDEACAMIRTDIDSMPTEMDSMKRKIFQLEIEKEALSKEKDVASKERLEVLEK ELSELKEKDKEMTAKYENEKSHITKIRDLKEKLDDVRGQMEKAEREYDLNKVAELKYG LIPALQREIEEKEKLIKENSNGNAMLKEEVTEQEISEIISKWTGIPVTRLVETERQKL LQLGDQLETRVIGQGEAVKAVTNAVIRARAGLKDPRKPIGSFIFLGPTGVGKTELAKT LARTLFDTEENIIRIDMSEYMEKYSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVIL FDEIEKAHDDVFNIFLQILDDGRLTDNKGKVIDFKNTIIIMTSNLGSNYLLDNESKEG IDESVRTRVKEALKARFKPEFLNRVDDIIMFKPLTVEDIKRIIDIFLDDIRKRLKDKN IQLRITDSAKDIMAKEGYDPIYGARPLKRYIEDTIETEIAKQIIAGNIYEGTTVGVDL KGESIVIERI" gene complement(3264..3992) /gene="" /locus_tag="" /db_xref="493915..494643" CDS complement(3264..3992) /gene="" /product="CobB/CobQ family glutamine amidotransferase" /translation="MELNICHLYPDLLNVYGDIGNILVLKYRAQQRGIKINVSNVSIK DSFPIDKYDIALFGGGQDYEQSIVSKDMVETKKNDLTEYIEKGKVLLAICGGYQLLGK YYTTPEGEKLDGLDILDIYTEGGDIRFIGNTVIKNEEFNETYVGFENHSGRTYIGNLK PLGKVIAGYGNNGEDQEEGCIYKNTFCTYFHGSLLSKNPELADRLLSTALKNKYGEEV ELEPLDDNLEFKAKEFIINRESKA" gene complement(4050..5411) /gene="" /locus_tag="" /db_xref="494701..496062" CDS complement(4050..5411) /gene="" /product="UDP-N-acetylmuramyl tripeptide synthetase-like protein" /translation="VCKINIKSFFSIIISKMVLKLSKTLFKGGTNFPGKVALKLDKKI LKTVAKDYKVILVTGTNGKTTTTSMIYNMIKDSNKFVISNSTGANMFPGIVACFVENF SFNNKEEKYAVIEVDEANVKFITEYVSPEIITITNLFRDQLDRYGEVYTTLKKILEGI EKSPNSKLILNGDESLLGDLNNSLPNKVLYYGFSHFKNADTVIDVNADSKFCKKCKHP YSYEFLTYNHLGSYYCENCGYKRPNIIFSLDEVEDLTPKGSLVIIDNQEYYINQPGLY NVYNALCAYSMAKTLGIEKSIIFNSLKSQKSSFGRQESINIEGKDVKIILVKNPAGYD QAINTIVLDKKKLNLALLLNDNYADGRDVSWIWDVKFEKLKSLDIDNILISGVRLYDM AIRLKIAGLPNEKFKISQNHDNLLEDIKSCKEETVYILATYTAMTSFRKFLNSKGYIK KLW" gene 5676..6656 /gene="manA" /locus_tag="manA" /db_xref="496327..497307" CDS 5676..6656 /gene="manA" /product="mannose-6-phosphate isomerase" /translation="MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFHQDL ISVIKNGKLKGKTLKDAIELYKNKLMGDCIFDKYKDFPLLLKIISAEKKLSIQVHPGE KDILDLKENPKKEAWYVMEAKVGSYIILGSKIKDKTVLKQVIDDGTVENYLYKVPVKK GDIFYIDSGMIHAIGKGVTLIEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPN KKSGLKVQLKNCNKTYCFLSEAFAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYG EGRQNLSRGDSILIPAYMGDYTLRGNMNLLKFYIPDIEKSINSIVNIIKC" gene 7006..8121 /gene="" /locus_tag="" /db_xref="497657..498772" CDS 7006..8121 /gene="" /product="lipoprotein" /translation="MYRKKLNLKTVCAFILILFINILLISCKSGNSNKGIIVEKWDNF YEGNNIHFYYSDGKSPNSQQLKSKYSLDKLTSKGKDDLDKALEITSWLNNKLKFSKNS IKTEEDTLTILEKYKEGETVSDKEFNEIFTEAISSVGIYSRIGEFRVKNAQHSKKNDF FMVSEIWSDKYKKWIMIDVVNSCYMSKAGVPLSAIEILNNGISSLEINGVKDKNKYIK KMERYFYSYTIGIDNNIHDGVKSNSYITYIQSGQLPELKTIKGYIKPTIFVNNDSLFT ISPKIEYKDLQNDKKPTLIISKKNIEGKEEETPSFYVASFKDSVMVTEFYISVNGADF GKVSTIFELKLKEGRNSIKLSENGKDVVREVIVNYKK" gene 8229..9083 /gene="" /locus_tag="" /db_xref="498880..499734" CDS 8229..9083 /gene="" /product="UDP pyrophosphate phosphatase" /translation="MLLILKAIIIGIVEGITEFLPVSSTGHMIIAGSLIGFDGTVYRK AYTDMFSVVIQLGAILAVVVLYWDKIISTLKNFFPSDRVPVKKCGLKFWINIVIASIP AAIIGIPFNDKIEEKLFYPLPVTIALIVGAIWMIYAENRYRNNSKVISIDDVNAKQAI IIGVFQCLALWPGMSRSASTIIGAWIVGLSTVAAAEFSFFLAIPAMIGASGMSLIKHN VFSTCSSIELIALAAGFIVSFIVALVVIDKFIAFLKKKPMKVFAIYRIVLGIVLIILI YTNIITWH" gene 9493..10994 /gene="rrsG" /locus_tag="rrsG" /db_xref="500144..501645" gene 11137..11214 /gene="" /locus_tag="" /db_xref="501788..501865" CDS 11137..11214 /gene="" /product="tRNA-Ala" /translation="WGYSSVGRAPALQAGGQEFESPYLH" gene 11138..11213 /gene="" /locus_tag="" /db_xref="501789..501864" CDS 11138..11213 /gene="" /product="tRNA-Ala" /translation="GGIAQLGEHLPCKQGVRSSNLLIST" gene 11219..11295 /gene="" /locus_tag="" /db_xref="501870..501946" gene 11429..14330 /gene="rrlG" /locus_tag="rrlG" /db_xref="502080..504981" gene 14461..14577 /gene="rrfG" /locus_tag="rrfG" /db_xref="505112..505228" CDS 14461..14577 /gene="rrfG" /product="5S ribosomal RNA" /translation="SGDYGLKVTPVPMPNTKVKLQSADGTAGEALWKSKSLP" gene 14585..14661 /gene="" /locus_tag="" /db_xref="505236..505312" gene 14586..14660 /gene="" /locus_tag="" /db_xref="505237..505311" CDS 14586..14660 /gene="" /product="tRNA-Asn" /translation="SAIAQRWSTRLLTDRLKVRILFAE" gene complement(15037..15900) /gene="" /locus_tag="" /db_xref="505688..506551" CDS complement(15037..15900) /gene="" /product="metallo-beta-lactamase family protein" /translation="MKLKKKNLIITCLLICLSIVFTACSQQSSNAVNTSNKSNELKVH YIDVGQGDSILVQTKDKNILIDAGTRKSSDSLISYLKKQHIKKLDYVIATHPHEDHIG GMPKVIEEFEISNFYAPKKTANTKIFKDMILQLKKKNLKINVAKKGISLDLSNNSSLD FLAPVKDNYENTNDSSAVIKLTHGNTKFLFTGDAEKTSEKDILNSNEDLSSNVLKVGH HGSHSSSSKEFLDKINPKIAIISCGKNNDYGHPHKETMKELNKRNIEVYRTDIDGNIV LTSDGENIKKN" gene 16037..16759 /gene="" /locus_tag="" /db_xref="506688..507410" CDS 16037..16759 /gene="" /product="1-acyl-sn-glycerol-3-phosphate acyltransferase" /translation="MKSFIFYLGFGFYMLLSLLRIIKLKYLKRKGNKEEIDRYINKSV VGWANFIVNGIGIKINKKGLENVPDGPCLFVGNHQGLLDVPVVVSSLDKYVGFVAKKE MLKLKILTYWMKEMKCVFMDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENL GEFKKGSMKLGIKAGVPIVPIAINGTYNVLEANGRKIKAADVDLIICPPIYPNELSKE EQNNLSATIKDIIQKELQKARN" gene 17491..18852 /gene="" /locus_tag="" /db_xref="508142..509503" CDS 17491..18852 /gene="" /product="HMGL-related enzyme" /translation="MMVKIVKSSYNHVLQNISSPNLYKDLFPYDEIPKVTFNDIQVPM DLPKDIWITDTTFRDGQQSMPPYTTEQIVKIYDYLHKLDNESGVIRQTEFFLYSEKDR KAAEICLDRGYKFPEVTSWIRASKEDFKLVKEMGIKETGMLMSCSDYHIFKKLNTTRE KAMSMYLEIAEEALANGIVPRCHLEDITRADFYGFVVPFVNKLMELSNKANIPVKIRA CDTLGLGVPYSGASLPRSVQGIIHGLRYCCNVPSERIEWHGHNDFYGVVANASTSWLY GCSSVNTSLLGIGERTGNCPLEAMIIEYGQLKGNTANMNLHVINEIAEYFEREMNYNI PSRTPFVGSEFNVTRAGIHADGILKNEEIYNIFNTEKILDRPVVVAVNQYSGLAGIAA WINTYFKLKGENKIDKKDERIVAIKEWVDNQYENGRTTIIGNNELEVIVKQLIPDLFR RAS" gene 18996..20921 /gene="" /locus_tag="" /db_xref="509647..511572" CDS 18996..20921 /gene="" /product="aconitate hydratase" /translation="LGLTLTEKIIKSHLVKGNMTKGEEIAIKIDNTLTQDSTGTMAYL QFEALGIDKVKTKRSVAYIDHNMLQSGPENADDHLYIQTVAKKHGIYFSKPGNGICHQ VNLERFGVPGETLLGSDSHTPTGGGIGMLAIGAGGLDVAVAMAGGEYYINMPKVVKVN LIGKLKPFVSAKDIILEVLRRLSVKGGVGKIFEYTGEGVKALTVPERATITNMGAELG ATTSIFPSDEITKDFLKAQEREEDYKYLVADEDAVYDEELEINLSELKPLAACPHSPD NIVPVSELKNIKVNQVAIGSCTNSSYRDMLRTASILKGKTVSENVSLVIAPGSKQVLN MMANNGALTDLVMAGARILECACGPCIGMGQSPCTDAVSLRTFNRNFEGRSGTKSANV YLVSPEVAAVSALTGYITDPTELTDFEDIEMPNKFLINDNLIIEPATEGEVVEVKRGP NIKPFPKAEALKELVTGKALTKVGDNITTDHIMPSNAKLLPYRSNVPYLSNFCLTPCD EEFPEKAKENGGGIIVAGTNYGQGSSREHAALAPVYLGIKAVLAKSFARIHKANLINN GILPLVFEREEDYDSIDEMDELVIENVLNQVEIGKIDIINKTKGIKYKTLLEATDRQK KMILKGGLLNLIKSSQQ" gene 20957..21955 /gene="" /locus_tag="" /db_xref="511608..512606" CDS 20957..21955 /gene="" /product="isocitrate/isopropylmalate family dehydrogenase" /translation="MKHNITLIPGDGIGPEVTEAARKVIDAVGVDINWHVVEAGEKVL DQYGTPLPDYVLDSIKETKVALKGPVTTPVGKGFRSVNVTLRKSLNLYANIRPVKSYK GIKSRYENVDLIIVRENTEDLYAGIEHMIGDDIAESIKVITKKASDRIVDYAFDMARK ENRNKVTAVHKANIMKLSDGLFLNCAKEVASKNKDIDFEDVIVDAMAMKLVLNPEKYD VLVMPNLYGDILSDMAAGLVGGLGLLPGANIGYEGAVFEAAHGAAPDIAGKNKANPTA CILSGAMMLNYIGENEKAKKIENAIEKVFVEGKCLTEDLGGSSTTEEFTKAIIENL" gene 22203..22988 /gene="" /locus_tag="" /db_xref="512854..513639" CDS 22203..22988 /gene="" /product="polar amino acid ABC transporter ATP-binding protein" /translation="MMEKVLAIDDYNKMIDREECMIETKNIKKTFGELIVFEDLNLKI KKGEVVVIIGSSGSGKSTFLRCLNGLEEINDGIIEIEGKTLNSKNKKSMKEVCSKMGM VFQNFNLFPHMTALDNVMIGPLVSKKENKEEVLKIAKNLLKKVGLEDKMDYYPSKLSG GQKQRVAIARALAMNPDIMLFDEPTSALDPELVGEVLSVMKKLAEEGITMVVVTHEMG FAKEVADRVIFMDGGKFVEEASPDVFFTCPKEERTKEFLKKVL" gene 23507..25273 /gene="" /locus_tag="" /db_xref="514158..515924" CDS 23507..25273 /gene="" /product="Na+/H+ antiporter family protein" /translation="MKKNREVLLTFSFVLMILLFNNMSVLAADLDPKVVAENASRLGI WTILPPVIAIVLAFITKNVVISLALGVFSGSFLLQLNGNNIFGASFKAFLDFINRILN SLADPWNAGIILQCMVIGGLIAVISKMGGAKAVAESLAKKAKTPKSAQIITWFLGLLV FFDDYANALIVGPIMRPVADKMKISREKLAFIIDGTAAPIAGIAVISTWIGYEISLIK DAYASIGQSVNAYGLFLSTIPYRFYNILILAFIVLIALMGRDFGPMLKAERRARTTGK LLSDTAKPMVSEESTELEPREGIKLNIWNAIIPIAILIIGAFAGFYYNGYQAIMGGED KALIQVLETSPASFDALRETFSASDASVVLFQSALLASIVAIIMGASQKIFKVGEAID VWITGMKSLIITAVILLLAWSLSAVIKELGTATFLVSILSNSIPKFLLPSIIFILGSV ISFATGSAYGTMGILMPLTIPLAYAISPDPTYVVISVSAVLTGAIFGDHCSPISDTTI MSSMGSACDHLDHTSTQMVYALTVAACTILFGYIPAGLGLPIYIVLPLSIGLVALLIR FVGKPNDIPEEESLEEVLEMDA" gene complement(25300..25515) /gene="" /locus_tag="" /db_xref="515951..516166" CDS complement(25300..25515) /gene="" /product="hypothetical protein" /translation="MKTLDIISLTLVIIGAINWGLIGFFRFDLVAALFGNMSAFTRVI YALVGIAGLYAISFYGRDRDEEPREEQ" ORIGIN 1 atggatattg aaaaattaac tttaaaggta cagcaagcta taaatgattc tcaacttgtt 61 gcagttaagt ataatcatca gcagattgat actatacatt tgttttcagc tctaatttct 121 caggatgatg ggttaattcc taatatttta gggaaaatgg gagtaaatat aagagacatt 181 aatgctgaaa ctaatagggt tttagatagt atgcctaaag tattaggcga gggagctcag 241 tcatcttctg tgtaccctac tagaagattt gaagaggttc ttgtaaaggc agagagtata 301 gcaaaggatt ttaaagattc atatataagt gtagaacatg ttttattagc agtaatggat 361 gtggatagaa atactgtcct tcctatacta gaaaaattcg gagtaaaaaa atcagagttt 421 ttaaaggcat tatcagctgt tagaggaagt caaagggttg ataatcaaga tccagagggg 481 acttatgaag ctttagtgaa atatggaaga aacttagtag aagaagctaa aaagcataag 541 ctggatcctg ttataggaag agatgaagaa ataagaagag ttgtaagaat tttatctaga 601 agaactaaga ataatcctgt acttattgga gaaccaggtg taggtaaaac tgctattgta 661 gaaggattgg cagagagaat tgtcagagga gatgtaccag aaagtttaaa aaataaaata 721 atattttctc tagatatggg agcacttatt gcaggtgcaa aatacagagg agaatttgaa 781 gaaagattaa aagcagtatt aaaagaagtt caaaatagtg aaggaagaat aattttattt 841 atagatgaaa ttcatactat agtaggggca ggaaaaacag agggttctat ggatgcagga 901 aatttaataa aacctatgct tgccagagga gaacttcatt gtattggagc tactaccttt 961 gatgaatata gacagtatat agaaaaagac aaagctttag aaagaagatt tcagcctgta 1021 ataacagatg aacctacagt agaggataca gtatctatat taagagggct taaagaaaga 1081 tttgaaatat accatggaat aagaatacat gattcagcta ttgtagctgc agctaagctc 1141 tctagtagat atattacaga tagatatctc ccagataaag caatagattt aatagatgaa 1201 gcttgtgcta tgataagaac agatatagat agtatgccaa cggaaatgga ttcaatgaaa 1261 agaaaaatat ttcaattaga aatagaaaag gaagcattgt ctaaagaaaa agatgtggct 1321 tcaaaggaaa gattagaagt cttagaaaag gaattgagtg aactaaaaga gaaagataaa 1381 gaaatgacag ccaagtatga aaatgaaaaa tctcatataa caaaaataag agatttaaaa 1441 gaaaaattgg atgatgttag aggtcagatg gaaaaggccg aaagagaata tgatttgaat 1501 aaagttgcag aattaaaata tggtttaata ccagctcttc aaagagaaat agaagaaaaa 1561 gaaaaattaa taaaggaaaa tagtaatgga aatgctatgt taaaagaaga ggttacagag 1621 caagaaattt ctgaaataat ctctaaatgg actggtatac ctgtaacaag attagttgaa 1681 actgaaagac aaaaactatt acaattagga gatcaattag aaactagagt aataggtcaa 1741 ggagaggcag taaaagcagt aactaatgca gttataagag ctagagcagg actaaaagat 1801 ccaagaaaac ctataggatc atttatattc ttaggaccta caggtgtagg aaagacagaa 1861 cttgcaaaaa ctttggccag aactttattt gatactgaag aaaatattat aagaatagat 1921 atgtctgaat atatggaaaa atattcagta tcaagactta taggagcccc tccaggatat 1981 gtaggatatg aagaaggagg ccagctaaca gaagccgtta ggagaaaacc ttatagtgtt 2041 atattatttg atgaaataga aaaagctcat gacgatgtat ttaacatatt ccttcaaata 2101 ttagatgatg gaagacttac ggacaataaa gggaaggtta tagattttaa aaatactata 2161 attataatga cttctaattt aggaagtaac tatttattag ataatgaaag taaagaaggc 2221 atagatgaaa gtgtaagaac aagagtaaaa gaggctttaa aggctagatt taaaccagaa 2281 tttttaaata gagtagatga cattataatg tttaaacctc ttacggtaga agacattaag 2341 agaataatag atatattctt agatgatata agaaaaagac ttaaagataa gaatatacag 2401 cttagaatta ctgatagtgc aaaagatata atggccaaag aaggttatga tccaatatat 2461 ggcgcaaggc cgctaaagag atatatagaa gatactatag aaacagaaat agcaaaacaa 2521 ataatagcag gtaatatata tgaaggtact actgtaggag tagacttaaa aggagagtca 2581 atagttatag aaagaatata aggaaattat ggcttaaaag gaagttatac tacccgcggt 2641 ttaaaaaagg gatatgtggt tagaaaggca actcacttca ataagagatt ctaacttatt 2701 ttttcttaaa atatatggtt ccaaatcata actcgctgaa cgctcagaca ataatttgga 2761 acatacatat attttgcaaa aacaactaag aatctctaat cttgttcaaa tgccttttac 2821 accacatatc cctatttttt aaaccacggg aagctagaat aactctttaa aaataatttt 2881 ctataggaca aaagcagtac aaaaggacga ttttactcca ctctgttacg taaaatccat 2941 aattatattt tccttttgta ggtttttctt tcagtaggaa attattataa caacctttaa 3001 aggtattaaa acaagaaata cttttagaga aaatagatat ctagaaaaat aataagaata 3061 ctttatttgt gaactaatat ttaagcgtga agtaaatagg acgtttactt agctctgttg 3121 ccacaggacg tggcattaga gcgttagctt aaatattagt acgcaaatat tagtattctt 3181 tatttttata gctatctatt gactaaaagt atttcttgtt ttaattttca acctttaaag 3241 tctgttaagt cgtaatttcc tttttatgct ttactttctc tattgattat aaattctttt 3301 gctttaaatt ccagattatc atctaaaggt tctagctcta cttcttcccc atatttattt 3361 tttagagcgg tagaaagtag tctgtctgct aattctgggt ttttggaaag tagagaacca 3421 tggaaatagg tgcagaaggt atttttatat atacagcctt cttcttgatc ttcaccgtta 3481 ttaccatatc cagctataac tttacctaaa ggttttaaat ttcctatata ggttcttcca 3541 gaatgatttt cgaaacccac ataggtttca ttaaattctt cattttttat tactgtattt 3601 cctataaacc taatatctcc accttcggtg tatatatcta atatgtctaa tccatcaagt 3661 ttttcacctt ctggtgtagt ataatattta cctaataatt gataaccacc acagatagct 3721 aataaaactt ttcctttttc tatgtattct gtaaggtcat tttttttagt ttctaccata 3781 tcctttgaaa ctatagattg ttcataatcc tgaccgcctc caaataaggc tatatcatat 3841 ttatctatag gaaaactatc ttttatagaa acattagata catttatttt tatgcctctt 3901 tgctgagctc tatattttaa tactagaata ttacctatat ccccatatac atttaataga 3961 tcagggtata aatgacatat attaagttcc atgtatttca ccttctttat attagttaga 4021 atgcttaatt taattgattt atatattaat taccacaact ttttaatata tcctttagaa 4081 tttagaaatt ttctaaaaga tgtcatagca gtatatgtag ctaaaatata tacggtctct 4141 tctttgcaac tttttatatc ctctaataaa ttatcatgat tttgagaaat tttaaatttt 4201 tcatttggga ggcctgctat ttttaatctt atagccatgt cgtataatct tacaccagag 4261 attaatatat tatctatatc tagagatttt aatttttcaa actttacatc ccatatccaa 4321 gatacatctc taccatctgc atagttatca tttaaaagta gggctaaatt taattttttc 4381 ttgtctaaaa ctatagtatt tatagcttgg tcatatccag caggattctt aactagtatt 4441 attttaacat ctttaccttc tatatttata ctttcttgtc taccaaaact actcttttga 4501 ctctttaatg aattaaatat gatagatttt tctataccta atgttttagc catagaataa 4561 gcacataggg cattataaac attatatagt ccaggttgat ttatgtaata ttcttgatta 4621 tctattataa ctagagaacc cttaggggtt aaatcttcta cttcatctaa agagaagatt 4681 atattaggtc ttttatagcc acagttttca cagtagtagc ttcctaaatg attataagtt 4741 aaaaattcat aagaataagg atgtttacac tttttacaaa attttgaatc tgcatttaca 4801 tctattacag tatcagcatt tttaaaatgt gaaaatccat aatatagaac tttattagga 4861 agagaattat ttaaatcacc taaaagtgac tcgtccccat ttaaaataag ttttgaattt 4921 ggagattttt caataccctc taatattttt ttcaaagtag tataaacttc tccataccta 4981 tctagttgat ctctaaataa gtttgttata gttattattt ctggagatac atattctgta 5041 ataaatttta cattggcttc atctacttct ataaccgcat atttttcttc tttattattg 5101 aaagaaaagt tttctacaaa acaagctact atgcctggaa acatgtttgc accagtactg 5161 ttggatatta caaatttatt actgtcttta atcatattgt atatcatact agttgtggtg 5221 gttttaccat tagttcctgt tacaaggatt actttgtaat ccttagctac tgtttttaat 5281 atttttttat ctaattttaa agcaactttt cccgggaagt tggttccacc tttaaaaagt 5341 gttttagaca gctttagaac catttttgaa attattatgc tgaaaaaaga ttttatatta 5401 attttacaca cttccttttt aaatttttaa ataaataaga ttacaactaa ctattataat 5461 ataattttga ctattttaca ttaatattaa taaaatcata atttaatttt ttaggtaaat 5521 tttcagataa tccgttcatt tttgttagaa ccctacattt ttgagtattc tctataggtg 5581 tgggacaata atcatttata tattttttat tttagaatat atattaaatg tatctaatat 5641 atattaagtg aattaattta tatttaagga gaaaaatgta ccctttaaaa tttgaaaaca 5701 tatatttaaa taaggtatgg ggaggaagag gcttaaaaaa atttagagat aatcttccta 5761 aaggtgatat aggtgaaagt tgggatatag catttcacca agatttaata agtgtaatca 5821 aaaatgggaa acttaagggg aagacattaa aagatgctat agaattatat aaaaataaat 5881 taatgggaga ctgcatattt gataaatata aagattttcc attactttta aaaataataa 5941 gtgcagaaaa aaaattgtcc atacaggtac atccaggtga aaaagacatt ttagatttaa 6001 aggaaaatcc taaaaaagaa gcctggtatg ttatggaagc taaagtgggt tcctatataa 6061 ttttaggtag taaaataaaa gataaaactg tacttaaaca ggttatagac gatggcacag 6121 ttgaaaatta tttatataaa gtaccagtaa agaaggggga tatattttat atagatagtg 6181 gaatgattca tgctataggt aaaggagtta cattaattga aattcaacag aacagcgata 6241 caacttatag attatatgat tataatagag gaagaaaact agatttagaa aaaggaatga 6301 attgtgtaaa tttagatatt aaacctaata aaaaatcagg cttaaaagtg caattgaaaa 6361 attgcaataa aacttattgc tttttgtcag aagcttttgc tatggaaaaa tatgaagtat 6421 attatttctt aaaagaaaaa agtgataaag aaagattttt tatttttacc tgtgtagatg 6481 gacaaggaca aattaattat ggtgaaggac gacaaaatct aagtagggga gatagtatac 6541 tcatacctgc ttatatggga gattatacat taagaggtaa catgaactta ttgaaatttt 6601 atataccaga tatagaaaag tccattaata gtattgtaaa tataataaaa tgttaaatag 6661 attttatgtt attagattaa aacaataaaa ttaaaagaag tatgtattat ataaagagaa 6721 atttataaat gatgtataaa ataggtttga ttttagaatt acaaggataa aaaatatacg 6781 taataaatta attcatgtga ttgttacgtg tattttttat ctctgttata ttaaaattaa 6841 atctatttta tatttagtct tcttttttaa gaaggtattc acaatatctt tttaattgaa 6901 aaatattgtg aatattatat aaataataaa aattttaaat taatactaga tacttaatat 6961 acgataaata tattaatata taaattgaga aaaaggggaa tttaaatgta tagaaaaaaa 7021 ctaaacttaa aaactgtatg tgcttttatt cttatattat ttattaatat attacttatt 7081 tcctgcaaga gtggaaatag caataagggt atcatagtgg aaaaatggga taatttttat 7141 gaagggaata acatacattt ttattatagt gatggcaaaa gtccaaactc tcaacaatta 7201 aaatccaagt attctttaga taagctcaca tcaaaaggaa aagatgattt agataaggct 7261 ttagagataa ctagttggtt aaataataaa ttgaagtttt ctaaaaacag tataaagaca 7321 gaagaggaca ctttaactat attagaaaaa tataaagagg gagagactgt ttcagataaa 7381 gaatttaatg agatttttac agaggctatt tcttctgttg gaatatattc aagaatagga 7441 gaatttagag ttaagaacgc tcagcatagc aagaagaatg attttttcat ggtttcagaa 7501 atttggagcg ataaatataa aaaatggata atgatagatg tggttaattc ctgttatatg 7561 tccaaagctg gagtgccatt aagcgctata gaaattttaa ataatggaat aagttcactg 7621 gaaataaatg gagttaagga taaaaataaa tatattaaaa aaatggagag atatttttat 7681 agctacacta taggtatcga caataatatt catgatggag ttaaaagtaa ttcatatatt 7741 acttatatac aaagtggaca attaccagaa ttgaaaacta ttaagggata tattaaacca 7801 actatttttg taaataatga ctctttattt actatttcac ctaaaattga gtataaagac 7861 ttacaaaatg ataaaaagcc tactctaata atatctaaaa agaacattga aggaaaagaa 7921 gaagaaactc caagctttta tgtagcttct tttaaagata gtgttatggt tacggagttc 7981 tatataagcg ttaatggagc agattttggc aaagtaagta ctatttttga attgaaatta 8041 aaagaagggc gaaactctat aaagctatca gaaaatggta aggatgtcgt aagggaagta 8101 atagtgaatt ataaaaagta ataaagatta ttattttctt atatgttcat taatatattt 8161 gtataagtca taaaaaatag tataatatag aaggtattaa ataaaaaaga gagtgaggag 8221 ttaggtcaat gctattaata ttaaaagcaa taataatagg aatagtagaa ggtataacgg 8281 aatttttgcc agtatcctct acagggcata tgataatagc tggatccctt ataggattcg 8341 atgggacagt gtatagaaaa gcttatacag atatgtttag tgttgttata caattaggag 8401 ctatattagc agtggtggtt ttatattggg ataaaattat aagtactctt aaaaactttt 8461 tcccaagcga cagggtgcca gtaaaaaaat gtggcttaaa attttggatt aacatagtga 8521 tcgcatctat accagcagca attataggaa tcccatttaa tgataaaata gaagaaaaat 8581 tattttaccc attgcctgta actatagctt taattgtagg ggctatatgg atgatatatg 8641 cggaaaatag atataggaat aattctaaag ttattagcat agatgatgta aatgctaaac 8701 aagctattat tataggagtg tttcaatgct tagcattatg gccaggcatg tctagatctg 8761 catctacaat aataggagct tggatagttg ggctatctac agtagcagca gcagaatttt 8821 cattcttttt agctatacca gcaatgatag gggcatcagg aatgtcatta ataaagcata 8881 atgtatttag tacatgctcc tctatagaat tgatagcttt agcagctgga tttatagtat 8941 cttttatagt agctcttgta gtaatagata agtttatagc atttttaaag aaaaaaccaa 9001 tgaaagtttt tgctatatat agaatagttt taggaatagt tttaataatt ctcatatata 9061 cgaatataat aacttggcat taaaatatta aagagcgttg ttatatagga ctattagcag 9121 tgtaaatctg ctaatagtcc tatattttta tatgatatca aagataactg tacccagtgt 9181 gtctttatat aaaaaagcaa aaaatatgaa gaatatcaaa gaattataaa aataatttta 9241 ttatattagg tatgatgagg caaatatgga tgaaagctgt gatagaatat taattgtcgt 9301 cgcgagatga caggtcagca aaaataaaaa aatgttgact aaaataaaaa aaagtgctac 9361 tattattaag cactgagaaa tggtctttga aaattaaaca gagaattaac aagaaacatt 9421 cttgtaacag ccagtaagat aaggtaataa accttgtcaa tgaatttgag aagagattaa 9481 acttttaaat ttagagtttg atcctggctc aggacgaacg ctggcggcgt gcttaacaca 9541 tgcaagtcga gcgatgaagc ttccttcggg aagtggatta gcggcggacg ggtgagtaac 9601 acgtgggtaa cctgcctcaa agtgggggat agccttccga aaggaagatt aataccgcat 9661 aatataagag aatcgcatga ttttcttatc aaagatttat tgctttgaga tggacccgcg 9721 gcgcattagc tagttggtaa ggtaacggct taccaaggca acgatgcgta gccgacctga 9781 gagggtgatc ggccacattg gaactgagac acggtccaga ctcctacggg aggcagcagt 9841 ggggaatatt gcgcaatggg ggaaaccctg acgcagcaac gccgcgtggg tgatgaaggt 9901 cttcggattg taaagccctg ttttctagga cgataatgac ggtactagag gaggaagcca 9961 cggctaacta cgtgccagca gccgcggtaa tacgtaggtg gcgagcgttg tccggattta 10021 ctgggcgtaa agggtgcgta ggcggatgtt taagtgggat gtgaaatccc cgggcttaac 10081 ctgggggctg cattccaaac tggatatcta gagtgcagga gaggaaagcg gaattcctag 10141 tgtagcggtg aaatgcgtag agattaggaa gaacaccagt ggcgaaggcg gctttctgga 10201 ctgtaactga cgctgaggca cgaaagcgtg ggtagcaaac aggattagat accctggtag 10261 tccacgccgt aaacgatgga tactaggtgt agggggtatc aactccccct gtgccgcagt 10321 taacacaata agtatcccgc ctggggagta cggtcgcaag attaaaactc aaaggaattg 10381 acgggggccc gcacaagcag cggagcatgt ggtttaattc gaagcaacgc gaagaacctt 10441 acctggactt gacatccctt gcatagccta gagataggtg aagcccttcg gggcaaggag 10501 acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttaggttaa gtcctgcaac 10561 gagcgcaacc cttgttatta gttgctacca ttaagttgag cactctaatg agactgcctg 10621 ggtaaccagg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg tccagggcta 10681 cacacgtgct acaatggtag gtacaataag acgcaagacc gtgaggtgga gcaaaactta 10741 taaaacctat ctcagttcgg attgtaggct gcaactcgcc tacatgaagc tggagttgct 10801 agtaatcgcg aatcagaatg tcgcggtgaa tacgttcccg ggccttgtac acaccgcccg 10861 tcacaccatg agagctggta acacccgaag tccgtgaggt aaccgtaagg agccagcggc 10921 cgaaggtggg attagtgatt ggggtgaagt cgtaacaagg tagccgtagg agaacctgcg 10981 gctggatcac ctcctttcta aggagaatag gaagaagaaa attctttcta aaggctgaat 11041 tctctgttta attttgagag actaatatct cttatataat taaaataagt taagataaat 11101 tatcttaact attagttatg gaatataact taaatatggg ggtatagctc agttgggaga 11161 gcacctgcct tgcaagcagg gggtcaggag ttcgaatctc cttatctcca ccatttaagg 11221 gtctatagct cagctggtta gagcgcacgc ctgataagcg tgaggtcgat ggttcgagtc 11281 catttagacc caccatgttc tttgaaaatt gcacagtgaa taagtaaagc taaaggtata 11341 aaatcctttg taattaaaat ggaactcact cagcagtgct gaggagtata gaattctaat 11401 aaatctaaga tttaaagaat tcttaatagg tcaagctaca aagggcgcat ggtgaatgcc 11461 ttggcactag gagccgaaga aggacgcgat aagctgcgat aagccttggg tagccgcaaa 11521 taggctgaga tccagggatt tccgaatgag gaaactcaca tgggtaaccc catgtattat 11581 gcactgaata cataggtgta taagggtaaa cccggggaac tgaaacatct aagtacccgg 11641 aggaagagaa agaaaaatcg atttcctaag tagcggcgag cgaacgggaa agagcccaaa 11701 ccagaaactt gtttctgggg ttgtggatag atcataaaag aagaggtatc ttaatcgaag 11761 agggctggaa cgccctacca tagaaggtaa tagtcctgta gataaaaaga gaaaacttcg 11821 agatctaatc cagagtacca cgagacacgt gaaaccttgt gggaagcagg gaggaccacc 11881 tcccaaggct aaatactacc tagtgaccga tagtgaagca gtaccgtgag ggaaaggtga 11941 aaagaacccc ggaaggggag tgaaatagaa cctgaaaccg tgtgcctaca accgatcgga 12001 gcacgttaaa gtgtgacgat gtgctttttg tagaacgagc cagcgagtta cgctatgtag 12061 caaggttaag tacttaaggt atggagccga agggaaaccg agtctgaaaa gggcgaaaag 12121 ttgcatggtg tagacccgaa accgggtgac ctatccatgg ccaggttgaa gcgagagtaa 12181 aatctcgtgg aggaccgaac cacgttggtg ttgaaaaacc atgggatgag ctgtggatag 12241 cggagaaatt ccaatcgaac tcggagatag ctggttctcc tcgaaatagc tttagggcta 12301 gcgtcgtgta attgagtaat ggaggtagag cactgaatgg gctaggggct atagtagtta 12361 ccgaacccta tcaaactccg aatgccatat acttgtatca cggcagtcag actgcgaatg 12421 ataagatccg tagtcaaaag ggaaacagcc cagaccatca gctaaggtcc caaagtgtaa 12481 gttaagtgga aaaggatgtg ggatttctaa gacaactagg atgttggctt agaagcagcc 12541 actcatttaa agagtgcgta atagctcact agtcaagaga tcctgcgccg aagatgtccg 12601 gggctcaaac ttaccaccga agctatgggt gtacactatg tgtacgcggt agaggagctt 12661 tctgtatggg ttgaagtcgt accgtaagga gcggtggatt gtacagaagt gagaatgctg 12721 gcataagtag cgagaaataa gtgagaatct tattggccga aaacctaagg tttcctgagg 12781 aaggttcgtc cgctcagggt tagtcgggac ctaagccgag gccgaaaggc gtaggtgatg 12841 gacaatcggt tgatattccg ataccgccta tttacgtttg agaaatgggg tgacgcagta 12901 ggataagatg tgcgcactat tggatgtgcg tctaagcact taggcatgct tgataggcaa 12961 atccgtcgag ctaagctgag gtgtgatggg gagccattta tggcgaagta tctgattcca 13021 cactgccaag aaaagcctct atcgagtgaa taggtgcccg taccgcaaac cgacacaggt 13081 aggtgaggag agaatcctaa ggccatcgga agaattgctg ttaaggaact cggcaaatta 13141 accccgtaac ttcgggagaa ggggtgccta cgaaagtagg ccgcagagaa taggcccaag 13201 caactgttta gcaaaaacac aggtctctgc taaagcgaaa gctgatgtat aggggctgac 13261 gcctgcccgg tgctggaagg ttaaggggaa cacttagcgt aagcgaaggt gtgaacttaa 13321 gccccagtaa acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg 13381 taagttccga cccgcacgaa tggcgtaatg atttgggcac tgtctcaaca gcaaatccgg 13441 cgaaattgta gtgcaagtga agatgcttgc tacccgcgat tggacggaaa gaccccgtag 13501 agctttactg tagcttagca ttgaatctcg gtattgtctg tacaggatag gtgggagact 13561 tggaaacttg ggcgtcagcc tgagtggagt catccttggg ataccaccct gacagtactg 13621 gggttctaac cggcggccat gaatctggtc acgggacatt gttaggtggg cagtttgact 13681 ggggcggtcg cctcctaaaa agtaacggag gcgcccaaaa gttccctcag cgcggtcgga 13741 aatcgcgcga agagtgcaaa ggcagaaggg agcttgactg cgacacatac aggtggagca 13801 gggacgaaag tcgggcttag tgatccggtg gtacctcgtg ggagggccat cgctcaacgg 13861 ataaaagcta cctcggggat aacaggctga tctcccccaa gagtccacat cgacggggag 13921 gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg aagtaggtcc caagggttgg 13981 gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag acagttcggt 14041 ccctatccgt cgcgggcgta ggaaatttga gaggagctgt ccttagtacg agaggaccgg 14101 gatggaccaa cctctggtgc accagttgtc acgccagtgg cacagctggg tagctatgtt 14161 gggactggat aaacgctgaa agcatctaag cgtgaagcca acctcaagat gagatttccc 14221 atagcgtaag ctagtaagac tcctggaaga acaccaggtt gataggtcag agatgtaagc 14281 atggcaacat gttaagttga ctgatactaa taagtcgagg gcttgaccaa aataaaattc 14341 actgtgtaat tttgaaagaa catctttcaa agaaaatatt aactttttaa aaggtaactc 14401 actcagcaag gctgaggagt actgatttaa aacgaaatcg aagatttctg taaatcagca 14461 tctggtgatt atggcttgaa ggtaacaccc gttcccatgc cgaacacgaa ggttaagctt 14521 caaagcgctg atggtactgc aggggaggcc ctgtggaaga gtaagtcgtt gccagataaa 14581 aatattccgc gatagctcaa cggtggagca ctcggctgtt aaccgatagg ttgaaggttc 14641 gaatcctttt cgcggagcca tttttatttt ttgacaaata tataatatta atataaaaag 14701 gatgttggta tattttattc caacatcctt atttgcatac aaaagtgcat ataaaagctt 14761 aatttaatgt agattcaatt tcaatacaga gttaatttta atatagcaaa aaaatacatt 14821 taataaacat atgaataagc tttagtagtc cttagcttgg tggaattaaa aattgaccta 14881 atttctcaca ggatatgaga agccagtagt gaagccagga aggcgcctct actgggtaga 14941 aaatttttaa tgtagccata tttagagtta cttagcaaaa tgaatagttt atgaatgtat 15001 tttttatttt tgcggtgtta aaatttaaac tatatactaa ttctttttaa tattttcacc 15061 atcacttgtt aaaactatat ttccatctat atctgttcta taaacttcaa tatttctttt 15121 attaagttct ttcatagttt ctttgtgtgg atgtccatag tcattatttt taccacaact 15181 tattatagct atcttaggat taatcttatc taaaaattcc ttagaggatg aggaatggct 15241 accgtggtga ccaactttaa gtacattaga agataaatcc tcatttgaat ttagaatatc 15301 cttttcactt gttttttctg cgtctcctgt aaataagaat tttgtatttc cgtgggtcaa 15361 ttttattact gcagaagagt catttgtgtt ctcataatta tctttaactg gagctaaaaa 15421 atctaaggag ctattattgg atagatctag agatatacct tttttagcta cattaatttt 15481 taaatttttc tttttaagtt gtaatatcat atctttgaaa atcttagtgt tcgctgtttt 15541 tttaggagcg taaaaattac taatttcaaa ttcctcaata acttttggca ttccacctat 15601 atgatcttca tgaggatgag tggctattac ataatctaat ttttttatat gctgtttttt 15661 taaatagctt attagactat cagaactttt acgagttcca gcatctatta gtatattttt 15721 gtcctttgtt tgaactagaa tgctgtctcc ttgtccaaca tctatataat gaacttttaa 15781 ttcattagat ttgttagatg tattaacagc gttagaggat tgttgagaac aagctgtaaa 15841 tacgattgat aagcatatca ataagcaagt tattattaag ttttttttct taagtttcat 15901 aaatccaact ccctgtgtta tgttaaataa agtatacatt atttaattct aacataaatt 15961 aaccaaaagt agataagttt ttttatatat attataataa taaagtgaag ttacataata 16021 aaaggagaga attataatga agtcatttat tttttattta ggttttggat tttatatgct 16081 actatccctt ttaagaataa taaaattaaa atatttaaag agaaaaggta ataaagaaga 16141 aatagataga tatattaata aaagcgttgt aggctgggca aatttcatag tcaatggtat 16201 aggaataaaa ataaataaaa aaggattaga gaatgtgcct gatgggcctt gcttatttgt 16261 aggaaaccat caaggattgt tagatgtgcc agttgtagtt tcatccttag ataaatatgt 16321 aggttttgta gctaaaaagg aaatgctaaa acttaaaata ttaacttatt ggatgaaaga 16381 aatgaaatgt gtttttatgg atagacaaaa tgttagagca gcagtaaaga ccataaatga 16441 aggtgtagaa aacttaaaaa atggatatag catgctgata ttcccagaag gtacaagaag 16501 tagaggagaa aatttagggg aatttaaaaa gggaagtatg aaattaggta taaaagcagg 16561 ggtaccaata gtgcctatag ctattaatgg tacctataat gtactggagg ccaatggaag 16621 aaagataaaa gctgcggatg tagatttaat aatatgtcca ccgatatatc ctaatgaact 16681 ctctaaagag gaacaaaata atttatctgc aactattaaa gatattatac aaaaggaact 16741 acaaaaagca agaaattaag aggagagtgt ctcaaaataa atttaatttt gagacattct 16801 ctttttttta ttattaagta tttcttagtt aaggtagact ttgattagaa taattatttt 16861 tctacagtta aacattatta agcgattttc agaagcagat tttctttatt aacagacttt 16921 ttagaagtca ttattcttta ggaaaagagt ttatccggga gcatagtagt atgtttagat 16981 agaaaagtag gtgtataaaa tcttagatag gtatcttcaa ttttaagcgg aaaattctaa 17041 tatatgattt ggtgtgagct gcttattaca aataaagtac tgaattagag agagtagtct 17101 ttacatagtg tgaaaggaat attagtacta atagaaatgg gataaaacgt aaattttgca 17161 agatagtaaa aaaaaatatc aattgtatga tttttaaagc aaaagcaaac aattgcaata 17221 tatttattta aaattgcaaa attagggtaa aaacatagtt gcttaatctt tagcaggatg 17281 ataaaatacg aattataaaa tatacataac cttacaatat aagttgaaca gtactgtgaa 17341 ttaataaata ttaaatatgt ttcttaatta taaatatgat ggataaaagt taaatattat 17401 ctaaaatgaa ggaaaagaat taaaaaatgc ataatatagt tttttgagaa aaatatgggg 17461 gaaaaccaat aaataaattt agggggaatt atgatggtta aaatagttaa gtcttcatat 17521 aatcatgtac ttcaaaatat atcaagtcct aatttgtata aggatctatt tccatatgat 17581 gaaataccaa aggtgacatt taatgatata caggttccaa tggatttacc aaaggatata 17641 tggattactg atacaacatt tagagatgga caacaatcaa tgccaccata tactacagaa 17701 caaatagtaa aaatatatga ctatcttcat aaattagaca atgaatctgg ggtaataaga 17761 caaacagaat tcttcttata ttctgagaaa gacagaaagg cagcagaaat atgtttagat 17821 agaggttata agtttccaga agttacttca tggataagag ctagcaaaga agattttaaa 17881 ttggttaagg aaatgggaat aaaagaaact ggcatgctta tgtcttgttc agattaccat 17941 atatttaaga aacttaatac aacaagagaa aaggctatga gtatgtattt agaaatcgcg 18001 gaagaagctt tagctaatgg aattgttcca agatgccatt tagaagatat aacaagagcg 18061 gatttttatg ggtttgtagt tccttttgta aataaattga tggaactctc caataaagct 18121 aatatacctg ttaaaataag agcctgtgac actttaggat taggggttcc ttatagtgga 18181 gcatcactac caagaagtgt tcaaggaatc attcatggac ttagatattg ttgtaatgtt 18241 ccttcagaaa gaatagagtg gcatggacac aatgattttt atggtgtagt agctaatgct 18301 tccacatcat ggctttatgg ctgctcatct gtaaatactt ctcttttagg tataggagaa 18361 agaacgggaa attgtcctct agaagctatg attatagaat atggacaatt aaaaggtaat 18421 accgctaata tgaacttaca tgttataaat gaaatagcag aatattttga gagagaaatg 18481 aattataata taccatcaag aacacctttt gtaggaagtg agtttaatgt tacaagagct 18541 ggtattcatg cagatggtat attaaaaaat gaggaaatat ataatatttt caatacagaa 18601 aagattttag acagaccagt tgtagttgca gtaaatcagt attcaggctt agctggtatt 18661 gcagcttgga taaacactta ctttaaatta aaaggtgaaa ataaaataga taaaaaagat 18721 gaaagaattg tggctataaa agaatgggta gataatcaat atgaaaatgg cagaacaaca 18781 ataataggaa ataatgaatt ggaagttata gtaaagcaac ttataccgga tttatttaga 18841 agagctagct agtaattacc atataatttc ataaaataaa aaaaatattt aaataaaacc 18901 ctataaataa aaactaaaga gagtataaat aaaaaattag taagtaaaaa acaaaagata 18961 aatattaaag tataaattga ttgggggaat aacagttggg tttaacatta acagaaaaga 19021 taataaaatc acatttagta aaaggaaata tgactaaggg agaagaaatt gctattaaaa 19081 tagataatac tttaactcag gattctacgg gaactatggc ctatcttcaa tttgaagctt 19141 taggtataga taaagtaaag actaaaagat cagtggctta tatagaccac aatatgttgc 19201 aaagtggacc agagaatgcg gatgatcatt tatatataca aacagtagct aaaaaacatg 19261 gaatttattt ttcaaaacca ggtaatggaa tatgtcatca agttaatttg gaaagatttg 19321 gtgtacctgg agaaacttta ttaggatccg atagccatac tccaacagga ggaggtatag 19381 gaatgttagc tataggtgct ggtggattgg atgtagcagt agctatggca ggtggagaat 19441 attatataaa tatgcctaaa gtagttaagg taaatttaat aggaaaatta aaaccttttg 19501 tatctgcaaa agatattatc ttagaagttt taagaagatt atctgtaaag ggtggagtag 19561 gaaaaatatt tgaatataca ggagaaggag taaaagctct tacagttcca gagagagcaa 19621 ctataactaa tatgggagca gaacttggag ctactacatc aatctttcca tcagatgaaa 19681 ttactaaaga ttttttaaag gctcaagaaa gagaagaaga ttataagtat ttagtagcag 19741 atgaggatgc tgtttatgat gaagaattag aaataaattt atcagagtta aaacctttag 19801 ctgcatgtcc acatagtcct gataatatag tacctgtatc agaacttaaa aatataaaag 19861 ttaatcaagt agctataggt agctgtacaa attcatctta tagagatatg ttaagaacag 19921 ctagtatact aaaaggaaag actgtatcag aaaatgtatc tttagttata gccccaggtt 19981 ctaagcaagt tctaaacatg atggctaata atggagcttt aacagattta gttatggcag 20041 gagcaagaat actagaatgt gcctgtggac catgtatagg aatgggacaa tctccttgta 20101 cagatgctgt atctttaaga acttttaata gaaattttga gggtagatct ggaacaaaat 20161 ctgctaatgt gtatttagta agtccagaag tggcagcagt ttcagcatta acaggatata 20221 taacagaccc cactgagtta actgattttg aagatataga aatgcctaat aaatttttga 20281 taaatgataa tttaataata gaaccagcta cagaaggaga agttgtagag gttaaaagag 20341 gaccaaatat aaaacctttc cctaaagcag aagctttaaa agaattagta actggaaagg 20401 cattaactaa agtaggggac aatataacaa cagatcatat aatgccatct aatgctaaac 20461 ttttacctta tagatctaat gtaccatatt tatcaaactt ttgcttaact ccttgtgatg 20521 aagaatttcc tgaaaaagct aaggaaaatg gaggaggtat aatagtcgca ggaacaaatt 20581 acggacaagg ttctagtaga gaacatgcag ccttagctcc cgtttattta ggaataaaag 20641 cagttttagc aaaatccttt gctagaattc ataaagcaaa tctaataaat aatggtatat 20701 tacctttagt ttttgaaaga gaagaagatt atgattctat agatgaaatg gatgaattag 20761 taatagaaaa tgtactaaat caagtggaaa taggtaaaat agatataata aataaaacta 20821 agggcataaa atataaaact ttattagaag caacagatag acaaaagaag atgattttaa 20881 agggcggatt attaaattta ataaaaagtt ctcaacaata gctacaaaaa tttggttaag 20941 ttttcggagg gatatgatga aacacaatat aactttaata ccaggagatg gtataggacc 21001 agaagtaact gaagctgcaa ggaaagttat agatgcagta ggagtagata ttaattggca 21061 tgtagtagag gctggggaaa aagttttaga tcaatatgga actccccttc cagactatgt 21121 tttagatagt ataaaggaga ctaaagtagc attgaagggt ccagtaacta ctcctgtagg 21181 aaagggattt agaagtgtta atgttacttt aagaaaaagc ttaaatttat atgcaaatat 21241 aagacctgta aaaagttata aaggaataaa atctagatat gaaaatgtgg atttaataat 21301 tgtgagggaa aacacagaag atttatatgc gggaattgag catatgatag gtgatgatat 21361 agcagaaagt ataaaggtaa ttactaaaaa ggctagtgat agaatagtag attatgcttt 21421 tgatatggca agaaaagaaa atagaaataa ggtaactgca gtgcacaagg ctaacataat 21481 gaaattatca gatggattat ttttaaattg tgcaaaggaa gttgctagta aaaataagga 21541 tattgatttt gaagatgtaa tagtagatgc tatggccatg aaattagttt taaatccaga 21601 aaaatatgat gttttagtaa tgcctaattt atatggtgat attttatcag acatggcagc 21661 aggtttagtt ggtggattag gattacttcc aggagctaat ataggatatg agggagctgt 21721 gtttgaagca gcccatggtg cagcacctga tattgcagga aaaaataaag ctaatccaac 21781 agcttgtata ctaagtggcg ccatgatgtt aaactatatc ggtgaaaatg aaaaagctaa 21841 aaaaatagaa aatgctatag aaaaagtatt tgtagaagga aaatgtctta cagaggattt 21901 aggcggaagt tctacaacag aagaatttac aaaggcaatt atagaaaatc tttaaattac 21961 tatataattc ttaatttgtt attacctttt aattagatat aaattttaga tctccttttt 22021 aaattatatt taagtttttc ttatgatttt aagattataa gaaaaacttt tttttataaa 22081 aattctattt tgttattttc aaaaagaagt taatatgata atatattagt ataaacttta 22141 ttactgtatt gatataaagt ggtgaaatta tatgaataga aattaaatat attgggggat 22201 taatgatgga aaaagtttta gctatagatg attacaataa gatgatagat agagaagagt 22261 gtatgataga aactaaaaat attaaaaaaa ctttcggcga gttaatagtt tttgaagatt 22321 taaatttaaa aattaaaaag ggagaagtag tagtaataat agggtcttct ggatcaggta 22381 aaagtacttt tttaagatgc ttaaatggtt tagaagaaat aaatgatgga attatagaaa 22441 tagaaggaaa gactttaaac tccaagaata aaaaatccat gaaagaagta tgttctaaaa 22501 tgggaatggt atttcaaaat tttaacttat ttcctcatat gactgcatta gataatgtaa 22561 tgatagggcc attagtttct aaaaaggaaa ataaagaaga agttctaaaa atagctaaaa 22621 atctccttaa aaaggttgga ttagaagata aaatggatta ttatcctagt aaattatctg 22681 gaggacaaaa gcaaagggta gctatagcaa gggcattagc tatgaatcca gatataatgc 22741 tgtttgatga accaacttct gctttagatc cagagttagt aggagaagtt ttatctgtta 22801 tgaaaaagtt ggcagaagaa ggtataacca tggtagttgt aactcatgaa atgggatttg 22861 ccaaggaagt tgcagataga gttattttta tggatggagg taaatttgta gaagaggcaa 22921 gtccagatgt gttttttaca tgtccaaaag aagaaagaac taaggaattt ttaaaaaaag 22981 tactatagaa ataaaattta aggtgtcaaa tacttttatt aatatacaaa ctttttaaaa 23041 ttttaatatt aataattttt gatggttttt tacagaaaaa tttatctaat actatggaag 23101 tattaaaatc attgggaaaa taacttgact atatatgata taaataatat aatgaattaa 23161 aagtgaatag taagtagata gaggtgcgat gttaatcagt acttttacga aggtaagcgc 23221 tatgaagtaa aaggaaaggg aatatcgccg aagtacacag ctgatgcttt aaggttgtat 23281 actggggttg catagaatat gtgtaacact gtcacaaatt tattttgtgg agagctatca 23341 ttcaaagtat tcgtactgtt ttatttatgt gcgcacaagt acgtctatat gccttgagtg 23401 taaagcttaa ggcttttttg tttttgatga tggttttcct ccccatattc acttaaattt 23461 taaagcttat agggcttgaa atttataaat agaggaggag atttttatga aaaaaaatag 23521 ggaagtttta ttaacttttt catttgtctt aatgatctta ttatttaata acatgtcagt 23581 attagcggca gatttagacc caaaagttgt agcagaaaat gctagtagat tgggaatatg 23641 gactatttta ccgccagtaa tagctattgt attagccttt attacaaaaa atgtagttat 23701 ttctttagca ctaggtgttt ttagtggaag ctttttatta cagctaaatg gaaacaacat 23761 attcggtgct agtttcaaag cttttttaga ttttataaat agaatactaa attcccttgc 23821 agatccttgg aatgcaggaa taatacttca atgtatggtt ataggtggtc ttatagcagt 23881 aatttctaaa atgggtgggg ctaaagctgt tgcagaatct ttagctaaaa aagctaaaac 23941 cccaaagagc gcccaaatta taacttggtt tttaggttta ttagttttct ttgacgatta 24001 tgctaatgcc cttatagtag gacctataat gagacctgtt gcagataaaa tgaaaatatc 24061 aagggaaaaa ttagccttta taatagatgg tacagcagca ccaatagctg gtatagcggt 24121 tatatctaca tggataggat atgaaataag tttaataaaa gatgcttatg caagtattgg 24181 tcaaagtgta aatgcttatg gattattttt atcaactata ccttataggt tttataatat 24241 attaatatta gcatttatag ttttaatagc tttaatggga agagattttg gaccaatgct 24301 taaggctgaa agaagagcaa gaactacagg taagctttta tctgatacag caaagccaat 24361 ggtttctgaa gaaagtacag aacttgaacc aagggaaggg ataaaattaa atatttggaa 24421 tgctataatt ccaatagcaa tattaataat tggagccttt gcaggttttt attataatgg 24481 gtatcaagct ataatgggag gagaagataa ggctttaata caagtgctgg aaacttcacc 24541 tgcatccttt gatgctttaa gggaaacttt tagtgcatca gatgctagtg tagttttatt 24601 tcaatcagcg ttacttgcaa gtatagtagc aataataatg ggagcttcac aaaagatttt 24661 taaagtagga gaagctatag atgtttggat tacagggatg aaatctttaa ttataacagc 24721 agttatatta cttcttgctt ggtctttaag tgcagttata aaagaacttg gaacagctac 24781 tttcttagtt tcaattttat ctaactctat accaaaattt ttattaccaa gcataatatt 24841 tatattggga tctgttatat cttttgctac gggatcagct tacggaacaa tgggtatatt 24901 aatgccttta acaattccat tagcttatgc tatatcacca gatccaactt atgtagtaat 24961 aagcgtaagt gcggttttga caggagcaat atttggagat cattgttctc caatatcaga 25021 cacaactata atgtcttcta tgggatctgc ttgtgatcat ttggatcata cctcaacaca 25081 aatggtatat gctttaactg tagcagcatg tacaatatta tttgggtaca ttccagcagg 25141 tttaggatta ccaatatata tagttttacc attatcaata ggattagttg cattattaat 25201 tagatttgta ggtaagccaa atgatatacc agaagaagaa agcttagaag aagttttaga 25261 aatggatgca taaaataagg aaagtgctta gcactttcct tattgttctt ctctaggttc 25321 ttcatctcta tctcttccat agaatgaaat tgcatataaa cctgctatac ctacaagagc 25381 atatataact cttgtaaatg cagacatatt tccaaataaa gctgcaacta agtcaaatct 25441 aaaaaaacca ataagtcccc agtttatagc cccaattatt actaatgtaa gtgaaataat 25501 atctaatgtt ttcat //