LOCUS NC_009699:17 18859 bp DNA linear BCT 03-SEP-2013 DEFINITION Clostridium botulinum F str. Langeland chromosome, complete genome. ACCESSION NC_009699 SOURCE Clostridium botulinum F str. Langeland chromosome, complete genome. COMMENT locus start: 2635745; locus end: 2654603 COMMENT n1_4mer:GRV/n1_4mer:RV = 2.582621; n0_4mer:D = 17.743799; n0_4mer:PS = 30.624924 FEATURES Location/Qualifiers source 1..18859 /organism="Clostridium botulinum F str. Langeland chromosome, complete genome." gene complement(1..1092) /gene="" /locus_tag="" /db_xref="2635745..2636836" CDS complement(1..1092) /gene="" /product="radical SAM domain-containing protein" /translation="MSKSHYIIPIFVAQEGCPHNCVFCNQHKITGEKNEMIDENYVRE TIEAYIKTIDRENSTLEVSFFGGTFTGIPIERQKSLLKVAKEYKDKGQIDYIHMSTRP DYIDREILDNLKKYSADIIELGVQSLDDEVLLKSGRGHSVEEVHRASKLIKEYGFTLG HQIMLGLPGDTFKKDIETVAKSLEMEPDIARIYPALVIKDTPMEYMLKKGTYKPYTLD EAIDITMLLYSMYEEQDVKVIRIGLQPTEEINENKDVLGGPFHPAFRELVEGKIINEA IFSHVEDSSEENLEIYINNKDISKLYCNKKQFFNEFINKKNVKRFKVIQDETLNRGNI IIKKSENQEHIFIKEYMRKLSEEGKNLFI" gene complement(1085..1789) /gene="rnc" /locus_tag="rnc" /db_xref="2636829..2637533" CDS complement(1085..1789) /gene="rnc" /product="ribonuclease III" /translation="LKNRQDVLKELQYKLKVYFKNEKLLDVALTHSSYANGKKNIKYY ERLEFLGDSVLQLIISEHLYQKYEDKKEGELTRKRAIIVCENSLYEIAKRWDLGFYLQ MSKGEELTGGRERVSILADCVESIIAAIYLDKGLDHAREFVMKNFKEIIEKAMKDEII LDYKTTLQEIVQQNNDLTINYELLKQEGPPHRRRFFTNVTIDNEVRGTGIGYSKKEAE QNAAREALKNLGDSHE" gene complement(1914..2147) /gene="acpP" /locus_tag="acpP" /db_xref="2637658..2637891" CDS complement(1914..2147) /gene="acpP" /product="acyl carrier protein" /translation="MIFEKIKATIAEQLSIDEEEITMESSFIDDLGADSLDIVELIMA LETEFDLEIPDEDAEKISTVGDVVDYIKSHTEE" gene complement(2225..3232) /gene="plsX" /locus_tag="plsX" /db_xref="2637969..2638976" CDS complement(2225..3232) /gene="plsX" /product="glycerol-3-phosphate acyltransferase PlsX" /translation="MIIAVDGMGGDFAPELVVEGCIQAVKEYEGIHIIITGKKELIKN ELDKREYNGNKIEILNSEEVISTNEAPVKAIRRKKDSSMVKALELVKEGKAQAVISAG STGALMAGATFVLGRIKGINRVCLAPLLPGAKAPFMIADAGANVDCKAEYLVQFAMMG KVYFESVLGVKSPTVGLVNIGAEEEKGNELTKAAYKLLKDTDFNFIGNIEPRDIPRGE VNIAVCDGFIGNTVLKTYEGVASNLFSMLKKEIMASTRGKIGGALLKPVFKDFKKKFD YTEYGGSPFLGAKGICIKAHGSSDAKAFKNAIRQAKICYDKKIIEEIENNLGNLIENN I" gene complement(3322..3504) /gene="rpmF" /locus_tag="rpmF" /db_xref="2639066..2639248" CDS complement(3322..3504) /gene="rpmF" /product="50S ribosomal protein L32" /translation="VGNPARKTSKAKRDSRKAQTFKLSLPGIVECPQCHEMKLAHRVC KSCGYYNGKEVVSNDK" gene complement(3518..4018) /gene="" /locus_tag="" /db_xref="2639262..2639762" CDS complement(3518..4018) /gene="" /product="ribosomal protein L32 family protein" /translation="MNLDVSDLIKKVELSKEVHLKLEDDKRFFDREEEILYLEAPTLD GVVSISEDILTLNGKLSAEIELSCSRCLQKFKHHVDTEVHESFTNNPQCEDDEIMLLE DEVIDVTEVIENNIIIELPIKRLCKENCKGLCQQCGANLNFSKCKCEKDIDPRLAKLK DFFSTQ" gene complement(4136..5329) /gene="ackA" /locus_tag="ackA" /db_xref="2639880..2641073" CDS complement(4136..5329) /gene="ackA" /product="acetate kinase" /translation="MKILVVNCGSSSLKYQLIDMTSEEALAKGLVERIGIEGSILTQK VNGEKYIIEEPMKDHKKAIELVLQALVDKEHGVISDMSEIAAVGHRVVHGGEKYASSV LINDEVMKALEDCVKLAPLHNPPNIIGINACRELMPKTPMVAVFDTAFHQTLPDYAYM YPLPYELYEQNGIRKYGFHGTSHRYVSSVASEMMEKDLKDIKVITCHLGNGASLCAVK EGKSVETSMGFTPLAGLAMGTRCGDIDPAILLFMERELKMSPDEVDTVINKKSGVLGI SGVSSDFRDIEGAAEEGNKRAKLALDVYHYTVRQTIGAYTAVLNGVDAIVFTAGLGEN SAASREEILNGLEYLGIKIDAEKNKQRGKQIEISTEDSKVKVFVIPTDEELMIARDTK EITAK" gene complement(5467..6465) /gene="eutD" /locus_tag="eutD" /db_xref="2641211..2642209" CDS complement(5467..6465) /gene="eutD" /product="phosphotransacetylase" /translation="MDLMKSLWEKAKSDKKKIVLAEGEEERNIEGCSKILKNELAHMI LIGNEEKINETAKKLNVSIDGAEIIDPQISEKVSTYTKEFYELRKHKGVTMEKAEQIV KDPIYFATMMVKMKDADGLVSGAIHTTGDLLRPGLQIVKTAKGASVVSSTFIMEVPNC EYGKNGMLLFADCAVNPNPTADELASIAISTAETAKALCDMEPKVAMLSFSSKGSAKH DLVDKVAEATKIAKEKRPDLDIDGELQLDAAIVQKVADLKAPDSAVAGKANVLVFPDL QAGNIGYKLVQRFANASAIGPICQGFAKPINDLSRGCSSDDIVNVVAVTAVQAQNM" gene complement(6799..7677) /gene="" /locus_tag="" /db_xref="2642543..2643421" CDS complement(6799..7677) /gene="" /product="hypothetical protein" /translation="MVKVVLGLLIILTIFFAVAFLRDYIKATKEGNIEKTNFFALGVV GFITNFFDTLGIGSFSPTTALLKNFKLSKDRTLPGTLNVACTVPVAAEAILFINGIEV EPVTLFSLLIAATVGAVVAAGVVSKLDERKVQFAMGTALIIVALVMLAGKLNLMPAGG DAVGLHGAKLIIAIIGNFILGALMTLGIGLYAPCMALVYSLGMSPKVAFPIMMGSCAF LMPAASLKFIKEGAYDRKASMAITVFGLVGVFIAYYLVKSLPLNILTWLVIVVIIYTA AMMFKSASKARKTVKA" gene complement(8044..8763) /gene="" /locus_tag="" /db_xref="2643788..2644507" gene complement(8793..9068) /gene="" /locus_tag="" /db_xref="2644537..2644812" CDS complement(8793..9068) /gene="" /product="hypothetical protein" /translation="MDLKYGDKILEMQGVIVDVSDGAVAIDFKGRLGYLKVPRRMIIS DYELKVGQEIGLNMSFVEVLSDEINEKYVSNLEIQKRRGLNPDERHK" gene complement(9077..11191) /gene="prdA" /locus_tag="prdA" /db_xref="2644821..2646935" CDS complement(9077..11191) /gene="prdA" /product="D-proline reductase subunit PrdA" /translation="MSMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVD SGLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDIIEGAKTIGGSEEKAEEISEELTE EDEKAVLKYNLKAGDTIKASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLTVDT PALTPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGAGKS VAVPAVKAEKGTVTAAPVAVEAKKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTT LYIRENICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPIATKEGSDAKLGEGV TRVIDGAIVMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPDKGEIFIKTQVTIKR GTGMERPGPLAAHKATDFITQEIREALKAVEDDSLVVNTETFEQVRRPGKKKVVVVKE IMGQGAMHDNLILPLEPVGVIGAKPNVDLGNVPVMLAPTEVLDGGIHALTCIGPASKE CSRHYFREPLVMECMQDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMDVDGAFV TTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGI ENEVLSCNTLCKEDAVRGLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKSTGNKI DRVLNETSIPMSEKRKEKYATK" gene complement(11224..12534) /gene="" /locus_tag="" /db_xref="2646968..2648278" gene complement(13528..14424) /gene="" /locus_tag="" /db_xref="2649272..2650168" CDS complement(13528..14424) /gene="" /product="hypothetical protein" /translation="MITKLLLSVLLVLTSYFLFFFLKDYFKSLKKGNLEENNFFIVGI IGLVVNFFDTLGIGSFAPLTSMLKFFKQTEDKVIPGTLNVGCTVPMILQAFIFMTGIK VEPVTLISMILAAMIGSLFGAEIVSKLDEKKVQFCMGVSLLVVALIILAGQLNLMPAG GNDIGLHGAKLIIAIIGNFILGILMTVGIGLYAPCMALVCVLGMNPKVAFPIMMGSCA FLLPMSSTKFVKNNAYDKKASISISIFGVVGVLIAAFIVKELPVRALTWMVVCVIMYT SITMFKAYYSKKESYETREELA" gene complement(14734..16752) /gene="" /locus_tag="" /db_xref="2650478..2652496" CDS complement(14734..16752) /gene="" /product="methyl-accepting chemotaxis protein" /translation="LKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINN KLEEGKKLTESINNWLEGKLLEVRSSANTPTAKLIETDVSAVDNFNAERIKFLEKNYP GEYDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTG KTLVVIGVPIKNKSEKTIGTMISAVNLLHIKQKVKEFKFGEKGYSLLIGKDGTILEHP DKSLVMQKKISEIKDENIQSLGKEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVAS VVSEKELFAPLNKLMLTLILITIVIVLIVATVIVFVAKQITLPLTKLSDFAEEIAEGN LTNKLEVHGQDEISKVTKALNNTVSKLKKMIGDISSSANDVMVISNGLASSTSESLKG NEEVSRSMQEIATGAVSQAEGASKASVVTRELVEDINEISKKCNYMIDIVEKSTNRST KVSQGVQQTVDSIKNIATTNKHNVEEIQNLLNQSKEIGQIVDVISDISEQTNLLSLNA AIEAARAGAQGRGFAVVADEVRKLAEQSSNSSKRIVELINGIQKQIEIISNKMNSGTS EVMHGVKMAKLIGNDFEEIEKVFNEVNNIVSEVSESTNTMEKKVNTTADIINNVAAVT EENSAATEEVTASNEEQIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS" gene complement(16860..17329) /gene="" /locus_tag="" /db_xref="2652604..2653073" gene complement(17774..18859) /gene="" /locus_tag="" /db_xref="2653518..2654603" CDS complement(17774..18859) /gene="" /product="hypothetical protein" /translation="MSFELPKFTPPDFTQDFLVNAPDCKTEEVVIEGVAPRHYHALSI YPEYFKIKGKWVIANESRMDTVAIVTPEDDIEVVEFRNLKLGDKVVVGRTEDASEGIY MYAGGFVAKDGNSDTFAFRSGRSRETAFSKDYDDLYEIMKYEKEHNGKITWVLGPSIA LDDESRAAFASLVENGYVNAILSGNTLATYDLEKGMFGTVLGQETFEAEKNAHYNYME AINEARRAGSLEELMASGKVKDGILKACVEKDVPVVLAGTIRDRFTLPNVYDNVYEAQ DAMRKHTRKSTMLICLSTVLHTIASGNMTPSYTVRDGVVRPVYIYSIDIQEFSVNKLS DRGTLEVKTLVTNAQDFITNIAKALVK" ORIGIN 1 ctatataaat aagttttttc cttcttctga aagctttctc atatactctt ttataaatat 61 atgttcttga ttttcactct ttttaataat tatattccct ctatttaatg tttcatcttg 121 tataacttta aatcttttca catttttttt atttataaat tcattgaaaa attgtttttt 181 attacaatac aatttagata tatctttatt atttatataa atttctaaat tttcttctga 241 actatcttcc acatgagaga aaatagcctc attaattatt tttccctcca ctaattctct 301 aaaagctgga tggaaaggac ctcctagcac atccttattt tcatttattt cttctgtagg 361 ttgaagtcct attcttatta cctttacgtc ttgttcttca tacatggaat ataatagcat 421 agttatatct atagcttcat ctaaagtata aggcttatag gttccttttt ttaacatata 481 ttccatagga gtgtccttta ttactaaggc tgggtatatt cttgctatgt ctggttccat 541 ctctaaagat tttgctaccg tttctatatc ctttttaaaa gtatctcccg gaagtcctaa 601 cattatttga tgtcccaaag taaatccgta ttcctttata agcttcgaag ctctatgtac 661 ctcttctaca gaatgtcctc ttcctgattt taaaagaact tcatcatcta aagattgaac 721 tcctaattca attatatccg cagagtattt tttaagatta tctaaaattt ctctgtctat 781 ataatctggt cttgtggaca tatgtatata atctatttgg cccttatcct tatattcctt 841 tgctactttt aaaagacttt tttgtctttc tataggtata cctgtaaaag tacctccaaa 901 aaaagaaacc tctaaagttg aattttctct atctatagtc tttatataag cttctatggt 961 ttctctcaca taattttcgt ctatcatttc attcttttcc ccggttattt tatgttgatt 1021 acaaaaaaca caattatgtg gacatccttc ctgagcaacg aatattggta ttatataatg 1081 gcttttactc atggctatca cctaaattct ttaatgcttc tcttgctgcg ttttgttctg 1141 cttctttttt actatagcct attccagttc ctcttacctc attatctatg gttacattag 1201 taaagaacct tcttctgtga ggaggacctt cctgttttaa taattcataa tttatagtga 1261 gatcattatt ttgttgcact atttcttgca atgtagtttt gtaatctaat attatttcat 1321 ctttcatagc tttttctatt atttctttga aatttttcat aacaaattct ctcgcatgat 1381 ctaatccttt atctaaatat atagcagcta ttatagactc tacacaatct gctaatatag 1441 ataccctttc tctgcctcct gttaattctt cccctttact catttgtaga taaaaaccta 1501 aatcccatct tttagctatt tcataaagag aattttcgca aactattata gctctcttcc 1561 ttgtaagctc tccttctttt ttatcctcat atttttgata taaatgctct gatattataa 1621 gctgcaatac ggaatctccc aagaactcca atctttcata atattttata ttttttttac 1681 cattagcata ggaactatga gttaatgcca catctaataa cttttcattt ttaaaatata 1741 ctttaagttt atactgaagt tcttttaaaa catcctgtct atttttcaaa attttcactc 1801 cctagaagtt cattcttcag tgtatttatt aaataaactc aagaataaac ttatctttta 1861 attatatctt ttaatataaa atccccgcta ataaaggcgg ggataaaaat caattattcc 1921 tcagtatgtg attttatgta gtcaactaca tctcccactg tagaaatctt ttctgcgtct 1981 tcatctggta tttctaaatc aaattcagtt tctaatgcca ttattaattc aactatatca 2041 agtgaatccg cacctaaatc atcaataaaa gatgattcca tagttatttc ctcttcatct 2101 atacttaatt gttctgctat tgtagctttt attttttcaa aaatcatttg tgtcacctcc 2161 taatgcttta tacataaata atattacata actatttata cgtcaatata ttcatgaagt 2221 tccattatat attattttct attaaatttc ctaaattatt ctctatttct tcaattatct 2281 ttttatcata acaaattttt gcttgtctta tagcattttt aaaggcttta gcatctgaac 2341 ttccatgagc ttttatacat atgcccttag cccctaaaaa aggtgatcca ccatattctg 2401 tataatcaaa cttcttttta aaatctttaa atacaggctt taaaagcgct cctcctatct 2461 tgcctctagt agatgccatt atttcctttt ttagcataga aaataaattt gatgctactc 2521 cttcataggt ctttagcaca gtatttccta taaatccatc acatacagca atattaactt 2581 ctcctcttgg tatatctctt ggttctatat ttcctatgaa attaaaatcc gtatccttta 2641 ataatttata tgcagctttt gtaagctcat tacctttttc ttcttcagcc cctatattta 2701 ctagtcctac tgttggactt ttaacaccta gtacactttc aaaatatacc tttcccatca 2761 tagcaaattg aactaaatat tctgccttgc aatctacatt agctcctgca tctgctatca 2821 taaaaggagc tttagctcct ggaagtaagg gtgctaaaca aactctattt atacctttta 2881 ttcttcctaa aacaaaggta gctcctgcca ttaatgctcc tgtacttcct gcggatataa 2941 cagcctgagc cttgccctcc tttactaatt ctaaagcctt taccatactt gaatcttttt 3001 ttcttcttat agcttttact ggtgcctcat ttgtacttat aacttcttcg gaatttagta 3061 tttctatttt gtttccatta tattctcttt tatctaattc attttttatt aattcttttt 3121 tacctgttat tattatatgt atgccttcat attcttttac agcttgtata catccttcta 3181 ctactagttc tggggcaaaa tctcctccca taccatctac agctattatc ataacatcac 3241 ttcctttcta atataaagta taagctaaat atttttcttt aacaagaaaa aaagaaagcc 3301 ttacgacttc cttttttata attatttatc gtttgataca acttctttgc cattgtaata 3361 tccacaactt ttacatactc tatgagcaag tttcatttcg tgacattgag ggcattcaac 3421 gattcctggt aagcttaatt tgaaagtttg agcttttcta gaatctcttt ttgcctttga 3481 agtttttctc gctggatttc ccactgtaaa cacctcctta ctgagtagaa aaaaagtctt 3541 ttagttttgc caaccttgga tctatatctt tttcacattt acattttgaa aaatttaaat 3601 tagcaccgca ttgttggcat aagcctttac aattttcctt acagagtctt tttattggta 3661 attctataat tatgttattt tctataacct ctgtaacatc aataacttca tcctctagta 3721 acataatctc atcatcttcg cattggggat tatttgtaaa actctcatgt acctctgtgt 3781 caacatggtg tttaaacttt tgaagacatc ttgaacaaga aagctcaatc tccgcactta 3841 actttccatt taaggttaat atatcctcag atatactaac taccccatct aatgttggtg 3901 cttctaaata aagaatttct tcttctctgt caaagaatct tttatcatct tctaacttaa 3961 gatgaacctc tttacttagt tctacttttt ttattaaatc ggatacatct aaattcataa 4021 aattcacctc aattatagca accacaattt attatataaa gggcatatta aaaagtcaag 4081 tattttataa gtaaatcaaa gttattatac ctatatttat aacttatatt acatattatt 4141 tagctgttat ttctttagta tctcttgcta tcattaattc ttcatcagtt ggtataacga 4201 atacctttac ctttgaatct tcagtactta tttctatttg ttttcctctt tgcttattct 4261 tttcggcatc tatcttaata cctaagtatt ctaatccatt taaaatttct tctctgcttg 4321 ctgctgaatt ttctcctagt cctgctgtaa atactatagc atctacacca tttaatactg 4381 ctgtataagc accgattgtc tgtcttactg tgtaatgata tacatctaaa gctagtttag 4441 ctcttttatt tccttcttct gcggcacctt ctatgtctct gaagtcacta cttactcctg 4501 atattcctaa tacacctgat tttttattta taacagtatc tacttcatct ggtgacatct 4561 ttaattctct ttccatgaaa agaagtattg ctggatctat atctccgcat ctagttccca 4621 tagctaatcc tgcaagtgga gtaaatccca tagaggtttc tactgatttt ccttctttta 4681 cagcacataa acttgctcca tttcctaagt gacaagttat tactttaata tctttaagat 4741 ctttttccat catctctgac gctacactgg atacatatct atgtgatgtt ccatggaaac 4801 catattttct tataccattt tgttcatata attcatatgg taatggatac atatatgcat 4861 agtctggtaa tgtttgatgg aatgctgtat caaatactgc taccattgga gttttaggca 4921 taagttctct acaagcattt attcctatta tgtttggtgg attatgaagt ggtgctaatt 4981 taacacaatc ttctaaagcc ttcataacct catcatttat aagtactgag ctagcatatt 5041 tttctccacc gtgaactact ctatgtccta ctgctgctat ttctgacata tcagatatta 5101 caccatgctc tttgtctact aatgcttgta aaactaactc tatagctttc ttatgatctt 5161 tcataggttc ttctattata tatttttctc cgttaacctt ttgagtcaat atagagcctt 5221 ctattcctat tctctctact aatccctttg ctaaagcctc ttcagaagtc atatctatta 5281 attgatactt taatgacgaa cttccgcagt taactactaa tattttcatt aattttccac 5341 ccttcatcta tatgttttat ataaaatttt attataagca aatctatttt ttttcgtgat 5401 attaatacat taatttatca tctaaaataa taaatcaatt gattatacaa aaattaaaat 5461 atttaattac atattttgtg cttgaactgc tgttacagca actacattaa ctatatcatc 5521 actgctacaa cctcttgata agtcattaat tggttttgca aaaccttgac atattggtcc 5581 tatagcactt gcatttgcaa atctttgaac taatttatat cctatatttc ctgcttgcag 5641 gtctgggaat actaaaacat tagcttttcc tgcaacggcg ctatctggag cttttaaatc 5701 tgcaactttt tgtactatag ccgcatctaa ttgtaattct ccatctatat caaggtctgg 5761 tcttttttct tttgctattt ttgtagcttc tgctacttta tctactaagt cgtgttttgc 5821 gcttcccttt gatgagaaag atagcatagc tactttaggt tccatatcac ataaagcttt 5881 agcagtttct gctgtagata tagcaattga agctagctca tctgctgttg gattaggatt 5941 tacagcacaa tctgcaaata aaagcatacc atttttacca tattcacaat ttggaacttc 6001 cattataaat gtacttgaaa caacagaggc tcccttagct gttttaacta tttgtagtcc 6061 tggtcttaat agatctcctg tagtatgtat agcaccagat actaatccat ctgcatcctt 6121 cattttaacc atcattgtag caaaatatat aggatcttta actatttgtt ctgctttttc 6181 catggtaacg cccttatgtt ttcttaattc ataaaattct tttgtatatg tagaaacttt 6241 ttctgaaatc tgtggatcta ttatttctgc tccatctata gaaacattta atttttttgc 6301 tgtttcattt attttctctt catttcctat taaaatcatg tgagctaatt cattttttaa 6361 tatttttgaa caaccttcaa tatttctttc ttcttctccc tctgcaagta caattttctt 6421 tttgtcactt ttagcttttt cccataagct tttcattaag tccattaaaa ctactccctt 6481 caaatataaa aattaaataa aatttacagt taactatgaa ataaatatat tatttcacaa 6541 gttttatgca aattattgta atatttttct cactttatct attaatttat ttataattat 6601 aaaaataaag tatttctatc tgctaattat ggataaatat gaatacacat atatatagta 6661 taaacacttt ttattaaaat tttcaacaat aaaattataa acttgaaaaa aaaccaggta 6721 aaatttaaat ttcacctggt tttcagcatt caatatttaa aagctttaca aatataattt 6781 aaatctaaaa catcatcttt aagcctttac tgtttttcta gctttagaag ctgatttaaa 6841 catcatagct gcagtgtaaa ttataacaac aattactaac catgttagta tatttaatgg 6901 taatgatttc actaaataat atgctataaa tacacccact agaccaaata cagttatagc 6961 catagatgct tttctgtcat aagctccttc ttttataaac ttaagtgatg ctgctggcat 7021 taaaaatgcg caagatccca tcattattgg gaaagcaacc tttgggctca tccctaaaga 7081 atatactaaa gccatacatg gagcatataa tcctattcct agagtcatta aagcacctaa 7141 tataaaatta cctattattg ctattataag ttttgcacca tgaagtccaa ctgcatctcc 7201 acctgctggc attagattta attttcctgc aagcattact aaagccacta ttataagagc 7261 tgttcccata gcaaactgaa cttttctctc atctaattta gatacaactc ccgcagctac 7321 tactgcacct actgtagctg ctattaataa agaaaataat gttacaggtt ctacttctat 7381 accatttata aataaaatag cctctgcagc aactggtaca gtacaagcaa catttaatgt 7441 acccggtaaa gttctatcct tagaaagctt aaaattttta agtaatgctg tagtaggaga 7501 aaaactacct attcctaaag tatcaaaaaa attagtaata aatcctacta ctcctaatgc 7561 gaaaaaatta gttttttcaa tgtttccttc tttagttgct ttaatataat cccttaaaaa 7621 tgcaactgca aaaaagattg ttaaaataat taaaagaccc aaaactactt ttaccatttt 7681 ctacacccct tttgatttaa tttttacaat ataattttaa tacaaattca tgtttttttc 7741 tatagatttt ttcatatttt ttgatatttt tttaacatta tttaagtagt attatataat 7801 tgactaaatt ttagaaaaat ttgaaataga attgtatatc tatattgttt caatttttct 7861 aaaagttaag actattgttt ttcttttgtg aaatgctttt cagtttgata aatttaaaac 7921 aatactaatt ttatatagga atttttttga tttatttcca tttacatatt tcaaattcaa 7981 ttggataatt tgttgttctt ttaaaagagc tctacttagc aaagtagagc tcttttttaa 8041 ttattaaact tttgctatat attcgtatgg taatggaaca acttttcctg ctgaaggaat 8101 cttaattaat tgttctaatg tttcttttac tattgctgtt tgcatttcta cattgttagg 8161 ttctcccgca ttagcaccca ttggaactct tggtgcaacc gctcttggtg taccagattg 8221 tttaacaact ggtggaagag cagctattat tattgtagga attcctattt cttcaatcgc 8281 tctctgcact ataactgcag atctatgaca agttcctcat ccagcagtca tcaatacagc 8341 gtctacgcct tcttctttta agattttagc aacttctggg cctgtttctt ctctgaattt 8401 ttgttggttt ccgccaccgc ccatgaatcc tatatgagtt ttagcaacag cttttataaa 8461 acctgcatct gctaattctc ttaatctatc tattgggaac atggcattta tatctttgtt 8521 aacgtctccg ttatcatatc caccgtgaga taccatcata tctgatgttt tcgcatctcc 8581 tggtactaat ctgtatgtga agtcacctgc taaattaaat cttttatctg attttaagtg 8641 aactcctgct gctgtagcta atgctactgt catatctttt agttccattg taactggcgc 8701 ccatactggg ttaggagtta taggaacaaa tatttctgat tgtaatccct ttacaatatt 8761 cattctagta accttccctt caatttataa atttatttat gtctttcgtc aggatttaga 8821 ccacgtcttt tttgaatttc taaattactt acatattttt catttatttc atcagataat 8881 acttctacaa aactcatatt taagcctatt tcttgaccta ctttaagttc ataatcagat 8941 attatcattc ttcttggtac ctttaagtat ccaagtcttc ctttgaaatc tatggctact 9001 gctccatcag atacgtctac aataacacct tgcatttcta ggattttatc accatatttt 9061 aaatccatct atatccctac tttgtagcgt atttttcttt tctcttttcg ctcattggta 9121 ttgaagtttc atttaaaact ctatcaattt tatttccagt agatttttct atcatttcaa 9181 tgttattttc tttaacattt gcattccaag ctctttctgg ttttttaact tcttctccag 9241 acatagctgc tttaatcatt gcaagacctc ttacagcatc ttctttacat aatgtattac 9301 aagataatac ttcgttttct attccacctt ctgatttgtt gttatctacc atatatttca 9361 tgtgtttgtt accaacaact agagcgcctt gaactgcgca gaatgagaat gctacacaag 9421 gaacacctct catacctatt tgttctacgt ggcttgcaaa gtcaatgtgg ttatttccaa 9481 aaccttcagt tgtaacaaaa gcaccatcaa catccatagc ttccaccatc atacctaatc 9541 tttcagatac atagaatttt tcactgttga tttgtggact tcctacaaat ataactcctg 9601 ctaaatctac ttcttcatct tgcatacatt ccattacaag tggttctcta aagtagtgtc 9661 ttgaacattc tttagaagca ggtccaatac aagttaacgc atggatacca ccatctaata 9721 cttctgttgg cgcaagcatt actggaacgt ttcctaaatc aacgtttggt ttagctccta 9781 ttactccaac tggttctaat ggtaatatta agttatcgtg catagcacct tgacccatta 9841 tttctttaac aactacaact tttttctttc ctggtcttct tacttgttca aaagtttcag 9901 tgttaactac taatgaatca tcttcaacag cttttaaagc ttctctgatt tcttgagtta 9961 taaaatctgt tgctttgtga gcagctaatg gacctggtct ttccattcct gttcctcttt 10021 ttatagttac ttgagttttg atgaatattt cacctttatc aggagcacct ggtcttcccc 10081 acataatgtt ttcttctaat ataccttctg aagaaccaaa ttcaccaact tgaactccgt 10141 cttcatctat gccagttacc attacaatag ctccatctat aactcttgta acgccttcac 10201 ctaacttagc atctgaacct tctttagtag ctattggttg tacgtccatt atagtttcac 10261 tataagtgtt gtacttatct ggagttatta tttctaattt tatatcttta actaattggt 10321 ctacattgaa tgcatcttca cagatgtttt ctcttatata aagagttgtt ccttcaattt 10381 tagtttcttt agctaattct actttatcta ttttatagtg ttttcttgta actgatctta 10441 ctattttttc ttctaattta acttcttttt tagcttctac tgctactggt gctgcagtta 10501 ctgtgccttt ttcagctttt actgctggaa cagctactga ttttcctgca cctacatttc 10561 catttaaagg aacttcgatg tcaattcctt ttccttcagc tattctgatt cttaaagttc 10621 caccacttat tgttgcttgt gtatcagcac tcatgtttac ttcctcctca aatccttcta 10681 atatatcagg tgttacagga gttaaagctg gcgtatcaac tgttaaagtt gctccaacta 10741 cttcttttct tgtaagaact ctttcatcta atgttagtaa aagagaatct acaagttttt 10801 caaaatgcat tggattttct aaatcactag cttttatagt atctcctgct tttaagttat 10861 attttagaac tgctttttca tcttcttcag ttaattcttc tgaaatttct tcagcctttt 10921 cttctgaacc acctattgtt tttgctccct caattatatc tggagttaat ggtgttaatg 10981 aatctacagt ttttaacaat ttagctccta ttacttcccc aacttttaaa caatcagctg 11041 gaatagttaa tagacctgag tctaccatat ctgggaatat ttctggatct tctaagttgt 11101 cagcagttaa tattgttccc tcttctgctc tacaacatac tactgcagat tcattcttta 11161 acgcctctgc atgctctggt gtcattgaca taagacataa cctcctattt ttttattttt 11221 ttgttattcc tgtggaagtc ttcttgttaa tgtgtaatca atagttctaa atatatgatc 11281 agtatgatga tatactggaa ctttagcttt tggagctatt tgcataactg tatttgaaca 11341 atcactacag tttgatatta atattctttc tgctccatct tttttaagct gcataactgc 11401 agccgcttgg cctggtcatt caccaggtgt tttacatttt cctggtccat ttcctttacc 11461 ctttgggtat tctatgtttt tgcagtcaac tattcctgca acttttgcat tcattttagt 11521 tgctacatct tttaatcttt cttcattagc tccacaggca catactagta gtcctaatgg 11581 tccattatac tctggtagtg gtattgtaac tattgctcca ccagatattt tagtaactgt 11641 atccttttct atgtctccag cttttccagt gtatggtcca cctatcacta gttcaccata 11701 ttcaccatct attccaccag atttttctat taaatctttt actggtgttc ccactggtac 11761 ttgtaagaat atatttggct tgttgcctga ttttaacttt cctattactg ttatatcttt 11821 atctataact ggctttcctt cttctacggc tcttgtaata tttgctaaag tttcagcatt 11881 cattacaatg cattttgctt ctatagggag ctctgttaca tctaaccact tatcaaatat 11941 tgcattgatt atagctcttt cttcacccat tggatataag tcagcaagag gtttaacttc 12001 tacatcagta gcacccttta aagctttttc taatgaagct atagcttcag gatgtttagc 12061 ttttatagct atatatcctt ttgttgagtt agtagctttc attgcatatc taacaccatt 12121 tattattaat tcaggtgttt cttctataac ttttatgtta tgatgaagtg ctggttcaca 12181 ttctacacag tttgctatga tataaccatc tttgttatct gcctttagtt ttatgtgagt 12241 tgggaaacct gctccgccgg ctccaactat tcctgcttca aatacagtat ctactaaatt 12301 atcacatttt tttatcttaa cgaattctgt tgtttgagct tcatctgctt ttatgatgat 12361 ttctttatct gtaacttttt ctactatacc ggacacacta gtatgaattt tagcaccaag 12421 tccgtttggt tctgctatac attctcctct tttaaccttt tgtccctctt ttacacaggg 12481 agcatctggt gcacctacgt gcatccttag aggaaaacta aacatttttt ccatggtatc 12541 cctccttgat ctatctacac acacttatat tatatagcaa tgtttatgcc aaatctataa 12601 tttaaataaa aaaagttaaa aaaaacacaa aataattagt tttttataca tttttacatg 12661 ttatttttta taaaaagtcc ttttttcgcc taaacatatt gtaaatttca atatattttt 12721 gtcttttttt tgacactttt gcggacaata tgtcaatatt tagacactat catttttttt 12781 tatcaattaa agccttatct atttgtattt ttaataacat tcttcgaatt atagtgtagt 12841 attttttgac accgatctgt aaacattgtc attactaata tttctacaaa gattttattt 12901 aattataggt aatttttaaa ttcatatttt attttaaact gtttttttta ttttattctt 12961 tttaattctt tttcagtaaa taagactaat aacttttata taaaacaata attgtaaaag 13021 atctatatgc tatatataaa aagaagaata cctaaaaatc taatccatat tgtcacctac 13081 tttatagatt catatttatc cgattactac ccgctctaat actcccatcg cactctgtga 13141 aagcgattcg caccaaatcg aagatttgga ctctctgctt ttcttcaaag tgggagtaaa 13201 gagcggttac gttcctggat aacgatttcc cctaaaggat aacgacttct aaggagtaaa 13261 actccttaga agtctgttaa taagcttcag atggagtaaa aactccctct gaagcttaga 13321 attctgttta taaaagagaa ccattatata ctttaaataa aaaaataaga gtttatacta 13381 aaattttagt acaaactctt agctccaatt ataagaccca attttatatg tttttttata 13441 aaaaataaaa acctacatta ttatatatat gatttaataa ctatactttt tttaattttc 13501 tttttaaaat tttatttata tatactatta agctaattcc tctctagttt cataactttc 13561 ttttttagaa taataagctt taaacatagt aatagaagta tacattatta cacaaacaac 13621 catccaagtt aatgctctaa caggaagttc tttaactata aatgccgcta ttaaaactcc 13681 tactactcca aatatactta tagatataga tgctttttta tcataggcat tattttttac 13741 aaacttagtt gaagacatag gtaataaaaa tgcacaggat cccatcatta tcggaaaagc 13801 taccttggga ttcataccta acacacaaac taaagccatg catggagcat acaatcctat 13861 tcccactgtc ataagtatgc ctaaaataaa attaccaatt atagctatta ttagcttagc 13921 accatgaagc cctatatcat taccgcctgc tggcattaaa tttaattgac ctgctaaaat 13981 tattaaagct acaactaaaa gggatactcc catacaaaat tgcacttttt tctcatctaa 14041 ttttgatact atctcagcac caaataaaga acctatcata gcagctagta tcatagaaat 14101 taaagttaca ggctctactt ttatacctgt cataaatata aaagcttgta aaatcatagg 14161 tacagtacat cctacattta atgttcctgg tattacttta tcctctgttt gcttaaaaaa 14221 tttaagcata gatgttaacg gagcgaaact tcctatacct aatgtatcaa aaaaatttac 14281 cactaaacct ataatcccta caataaaaaa attattctct tctaaattac ctttctttaa 14341 tgatttaaaa taatccttta aaaagaaaaa taaaaaatag cttgttaaaa ctagtaatac 14401 tgataataat aattttgtta tcattgatat tccccctatc ttctccatag tattttgttt 14461 tcaattcact ggtaaacctt ttcattgggt ataaaatttt tttaaaatag atgaatattc 14521 ccccaaagaa tagtaacaac ttctttttca atgatgtttg cactaccttt ttaaatgata 14581 tctcataccc cttacattat aagacattta ttgcaaaatt actatagttt ttatctattt 14641 ttgtagatat ttctaaaaga tttaataaaa aaagcttata atctttattt tgtaagatta 14701 taagctttct atataaatta cttttaattc tatctaggat aatttaaatt tatatactgt 14761 atccttgagt tttttaacta attcttctaa tgtataagtt gagtctacaa tttgatgcat 14821 aaaagcaatc tgctcttcat ttgatgcagt gacttcttct gtagctgctg aattctcttc 14881 tgttacagct gcaacattat ttataatatc agctgtagta tttactttct tttccattgt 14941 attagtagac tctgatacct ctgatacaat attattaact tcattaaata ctttctctat 15001 ttcttcaaaa tcattaccaa ttaattttgc cattttaact ccatgcataa cttcacttgt 15061 tccagaattc attttatttg atatgatttc aatttgtttt tgaattccat taataagctc 15121 tactatcctt tttgaagaat tacttgactg ttctgccaat ttcctcacct catctgcgac 15181 tacagcaaat cctctacctt gtgcaccagc cctagcagct tcaatagctg cattaagtga 15241 taaaagatta gtttgttcag atatatcact tattacatca acaatttgtc ctatttcttt 15301 agattgattt aataaatttt gaatttcttc aacattatgt ttatttgttg tagctatgtt 15361 ctttatacta tctacagttt gttggactcc ttgtgaaact tttgtgcttc tattagttga 15421 tttttctact atgtcaatca tatagttaca ttttttagat atttcattta tatcttcaac 15481 taattctctt gttacaacag atgctttgct tgccccttct gcctgagata cagcccctgt 15541 ggctatttct tgcatacttc gtgaaacttc ttcatttccc tttaatgatt cacttgttga 15601 tgatgctaaa ccattagata ttaccataac atcattagcc gaactactta tatcacctat 15661 cattttttta agctttgaaa ctgtattatt tagtgctttt gtcaccttag aaatttcgtc 15721 ttgcccatga acttctaatt tatttgtaag atttccttct gctatttctt ctgcaaaatc 15781 agataactta gttaatggta atgtgatttg ttttgctaca aatacaatta ctgttgcaac 15841 aatcaataca attactattg ttattaaaat taatgttaac attaatttat ttaaaggagc 15901 gaacaattcc ttttcagaca caacacttgc tacattccac cccgatagag gaactttatt 15961 ataaaataca atcgatttat tatctccact tccaaatcta aatacacctg atttattttc 16021 catcatttct tttcctaatg attgtatatt ttcatctttt atttctgata tctttttttg 16081 cattactaat gacttatctg gatgctcaag aatagttcca tcctttccaa ttaataaact 16141 atatcctttt tcaccaaatt taaattcctt aactttttgt ttaatatgta aaagattcac 16201 agcagatatc attgttccta ttgttttttc tgatttgttt ttaattggaa ctcctattac 16261 aaccaaagtt ttaccagttc cctttgatac tacaggatta gatatattat atggtacccc 16321 actcattaaa tccttgtacc atgttttttc tgatacatcg ccatttacaa actttccatt 16381 tgaatattga gctctagatt taccatcatt attaaataaa gttgctgctg cattgtcata 16441 ttctcctgga taattttttt ctaaaaattt aattctttct gcattaaaat tatctacagc 16501 agaaacatct gtttctatta gttttgccgt aggtgtatta gcagaacttc ttacttctaa 16561 aagctttcct tctaaccaat tgtttatact ctcagttagt tttttccctt cctccaattt 16621 attatttata agttcatttt caatattttt tctaaattca taaaatgttg taaaactcaa 16681 aattgacatt ccaattatta caactggtaa aatcgtaatt aataatttca ttttaaagga 16741 cagttttttc aatattttca tcactcccgt aattccaatg gtaattaatt tgtaacaatt 16801 tataaaatta tttagaagat gtaacttata aagttacatc tattataaaa aaaatttatt 16861 tacttctcaa ttttttttct tataccttca actatgtatt tcattgttat atttcctaat 16921 acttgattca taacttcttg agctttcacc cctccctttt caagcactgc ttgaatattg 16981 gcaccagtgg aataatttag atttgatgat tcatagaatc aaaatattcc tcctttttga 17041 acaacatcaa caaccctata tatatcaatg ttatttgtgc tagatctttt aataaataaa 17101 ctccaccagc acctgttata acattaacta aactagctct ttttcacatt atcattactc 17161 ttcttataac aaccggatta atatttacgc tatctgttat ccattcagaa gtacataaat 17221 tgctatcctc catggataat aaagataaaa tataaactac tacagaaaac ctactgctta 17281 ttttcttttt tatcgtcctc gttgtaacta ttatagtttc atcaaacatt aaagtcaata 17341 gttcttatga aatttttaag caaactatca aaattaatta aatatactaa aatttactct 17401 tacaagtaaa tcctatattc ttaacttcat tgcatttttc acattctaat ttaatataag 17461 catatcttcg tccttatatc tcaaaacttt atcgatctct ggctttatgt taggtctaat 17521 cttcttgtta tacactttac aaaattattc caatgttctt atagtattag tttcattttc 17581 ctttttttat tcgtatacct cttaatatat taattataag ttagcatatt aaagcgttgg 17641 aaactagatt ttatctagct ttcagtattg ggaaattcta tgatttcctg taaaataaaa 17701 aagagaatct ttaaaaagac tctctttttt acgaaaattt atgaaattta atatataaaa 17761 aaatttttaa atactattta actagtgctt tagctatatt tgtaataaag tcttgagcat 17821 ttgtaactag agttttaact tctagggtac ctctatctga taacttatta actgagaatt 17881 cttgtatatc tatagagtag atatacacag gtctaacaac gccatctctt actgtataag 17941 atggagtcat gtttcctgaa gctatagtat gtagcactgt agataaacat ataagcattg 18001 tagactttct tgtatgtttt ctcatagcat cttgggcttc atatacatta tcataaacgt 18061 taggtagagt aaatctatct cttatagtac cagcaagtac tacaggaaca tctttttcta 18121 cacaagcttt taatatacca tctttaactt ttccagaagc cataagttct tctaatgaac 18181 cagctcttct agcttcgttt atagcttcca tatagttata gtgagcattt ttttcagctt 18241 caaaagtttc ttgtcctaaa actgttccga acattccttt ttctaagtca taggttgcaa 18301 gagtgtttcc agataaaata gcattaacgt atccgttttc tacaagggaa gcaaaagctg 18361 ctcttgattc atcatctaat gcaattgatg gtcctaaaac ccaagttatt tttccgttat 18421 gttctttttc atatttcatt atttcataca aatcatcata atctttagag aaagctgttt 18481 ctcttgatct accacttctg aatgcaaaag tatctgaatt tccatcttta gctacgaatc 18541 ctccagcata catgtatata ccttcgctgg catcttcagt tcttcctact acaactttat 18601 ctccaagttt aagatttcta aattctacaa cttctatatc atcctctgga gtaacaattg 18661 caacagtatc catacggctt tcgttagcta ttacccattt tcctttaatt ttaaaatatt 18721 caggatatat tgataaagca tggtagtgtc taggggcaac tccttctata actacctctt 18781 cagttttaca atccggtgca ttaacaagaa aatcttgtgt aaaatctggt ggcgtaaatt 18841 ttggtaattc gaaactcat //