LOCUS NC_009633:8 18228 bp DNA linear BCT 07-SEP-2013 DEFINITION Alkaliphilus metalliredigens QYMF chromosome, complete genome. ACCESSION NC_009633 SOURCE Alkaliphilus metalliredigens QYMF chromosome, complete genome. COMMENT locus start: 760872; locus end: 779099 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.715862; n0_4mer:D = 26.838695; n0_4mer:PS = 41.662606 FEATURES Location/Qualifiers source 1..18228 /organism="Alkaliphilus metalliredigens QYMF chromosome, complete genome." gene 1..1230 /gene="" /locus_tag="" /db_xref="760872..762101" CDS 1..1230 /gene="" /product="lytic transglycosylase catalytic subunit" /translation="MNKRMLSLFVMILLTVQWVTVGVQVNAANPSHEQIKEIIEEVAL EKNIPAVILKAIADKESKFRQFTDSGAPFVSNGNTGIMQVNRVHHGTYDVQRLREDLR YNIEAGADILQSKWDWSVVPTIGDGDPNIVENWYFALWAYNSWDGRNNPNIHGSGVYQ EELLQLVREKYNQPVTSIDWSLIPRSGTPSGGTQVATPEKHHYAVAEEKKEEKIFVVT RSGGNRSIFRDVADHQQEMYIESIVKEEIMSGVGQELFKPDDLITREQVAKVIVDALD LEVVDETMAVSKIVDWHEVSGWARDFMSIVYQLEIMTGYEDGTLRPSDFVTREQAAVI LASGLNTNTMIMTAEPYEDQEKISPWAIDSINELKTLGILQRDNRLRPKDYITRAEFS KWIYYLLRYDSDALRLQ" gene complement(1172..1705) /gene="" /locus_tag="" /db_xref="762043..762576" CDS complement(1172..1705) /gene="" /product="hypothetical protein" /translation="LVSYHYKNPQMIPQFVRYLSLNLPDEFIVLCIGTDRCIGDALGP LVGSLLLQKHFPHLIYGTLGQPIHALNLKNTITMLKQKHPNAFILAIDASLGDSEQVG FITLRPGPIAPGKGVGKALPSVGDLSLIGIVAPNDEKINSTIHHIRLSLIMDLAQQIT EVLMHHCHIAGDNKSTY" gene complement(1778..1933) /gene="" /locus_tag="" /db_xref="762649..762804" CDS complement(1778..1933) /gene="" /product="hypothetical protein" /translation="VNHINNLKDRIEELKEQLSRSLDEGRATYDIVDLSQELDELIVE YYLLNNE" gene 2222..2689 /gene="" /locus_tag="" /db_xref="763093..763560" CDS 2222..2689 /gene="" /product="putative small multi-drug export" /translation="MESAFQWMTKELMVLFIAALPIMELRGAIPIGVSMGIHPLHATI LGVVGSLLPVPFLLLFLEPVFEKLKKSKFFFKFIQRTVKKTRKSSERIRKYSTLGLVL FVAIPLPTTGVWSGCLAAKLLAVPFKYAMPAIAVGASIAGTIMFILSYIAIKI" gene 3068..4252 /gene="" /locus_tag="" /db_xref="763939..765123" CDS 3068..4252 /gene="" /product="S-adenosylmethionine synthetase" /translation="MGKRLFTSESVTEGHPDKICDQISDAVLDAIFEKDPKARVACET SVSTGLVLVAGEITTDCYVDIPKVVRRTIAEIGYTRAKFGFDSDTCAVLTAINEQSPD IAQGVNEALENRAGEVTDGLESIGAGDQGIMFGFACNETPELMPLPISLAHKLAKRLS DVRKNGTLDYLRPDGKTQVTVEYDGDKPKRVDTIVISTQHSPEVDHKTIERDLIEYVI NNIVPAELIDAKTRYLINPTGRFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGK DPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGVAQPVSILVETFGTGKVDED KMIELVHKYFDLRPAAIIRDLDLRRPIYRQIAAYGHFGRTDVDLPWERTDKAEALRAE VL" gene 4461..5033 /gene="" /locus_tag="" /db_xref="765332..765904" CDS 4461..5033 /gene="" /product="ECF subfamily RNA polymerase sigma-24 factor" /translation="VNQDFEARVLEAKAGNRQAKEWIVFKLNPLVISHSGRYGGCKGY DEDAIQDGRMKILEAIETFDLEKGVPFLGYVALAVQHFYQNRRRKQRIHLSLDSPIGN GVEEENGTWIDLIVDESVEIEEDLIRKETHQWIHENMSCLSQGQQQVVRDFYFNKHSL KTIAAKRGVHPITVAKTKGLALRKLRRQAT" gene 5390..7438 /gene="" /locus_tag="" /db_xref="766261..768309" CDS 5390..7438 /gene="" /product="methyl-accepting chemotaxis sensory transducer" /translation="MESTKNVKRIRKGSIKMKLVVIPLIVSLLAVGAIGFLSTHFTRD SMLEQMREDGFYTAERLIGRIEDNNDSLESMDEVLEDQIRGVANVVMGNRAIISNEYL VELAAQLDVHRIHYWSTDTMKIAYTATDGFVGLDAPVEHVLHDFHASGAAEIMEEARQ SAETNESFKFGYVKTPDGDVIQVGISADRIHELTENLSYQSLVEDLADNEKVVYALFI DRNLEAQAHSNRERIGIELDDEGSIAAAVNGESYAWEYFYEAADLNVYDVLLPIEIEG QHLGAINIGFSMAEVDSAISRNIMMVAITGIVAFIILGMVLFTLSNDAVKTLNKLKDQ MALMGNGDFTKDVSQDIINKNDEFGEIGHAIKSMQTTIKAMISNIANTSQQLASSSEE LTATSQQSATAADEVAKTIEEIAGSANEQAKDTENGVLKTDELSKIIEEDLKDMEEIN NTIEQLTILKDDGIGIVKELTNKTNNSDQAIKTIYQSTVDTNESAERIGEASKIIEGI AEQTNLLALNAAIEAARAGEAGKGFAVVAEEIRKLAEQSTVSVNEIDEMLKKLQSNSQ SAVNVMETVLSTIKEQVESVSMTEGKFDGIAEQVERVRAVVKKSTDSVNVMNLTKDEL ANIMQSLAAVAEENAAGTEEASASVEEQTASMEEIASSSESLARLAEDMQESISKFNY" gene 7643..7864 /gene="" /locus_tag="" /db_xref="768514..768735" CDS 7643..7864 /gene="" /product="hypothetical protein" /translation="MPINIMNETSRVRLRFVDRIDEEGRERLVTRTYSNVKPEAADEA LYNASATIVGLQSKPLKTIIRADEKELVE" gene 7900..8118 /gene="" /locus_tag="" /db_xref="768771..768989" CDS 7900..8118 /gene="" /product="hypothetical protein" /translation="MNQVLALSFMKGDGTKLRMTVPHPREDVTGAEVKTAMDEIIASD VFAPGGIALTGVDEARIISTQEDVLELV" gene 8178..8342 /gene="" /locus_tag="" /db_xref="769049..769213" CDS 8178..8342 /gene="" /product="hypothetical protein" /translation="MNDVFGHVANLGFPIVVSVYLLVQIEEKLEGLTVSIHELAKSIE RLTMKRPEGL" gene 8360..10624 /gene="" /locus_tag="" /db_xref="769231..771495" CDS 8360..10624 /gene="" /product="recombinase D" /translation="MRVTGGSAVVELEGQLVEIIFQNESNGYMVGILEAKEEIATIVG CLPAIKEGEQLAVKGKWAVHPVYGRQLEVGEYRPIQPSTKEGILNYLSSGVIKGVGKK MAERIVDLFGMDSLEVIQYAPERLREVEGIGRAKAETITETFRDQKELREIILFLSEY HITPNYAVKIHKKYGDKTIATIQENPYRLADEIVGIGFKRADAIARNMGVHPHSKYRI HSGIKYMLNTFQGEGHTYAPGVKLIQRAEELLRVEEGQVEGAIQELALNQEIQLERID DEIIVYSMPYYYAESNVCKKLISLAQVELDPIEMDIDEELQKIEQAEEMTLAKQQKEA IKEAIENGISVITGGPGTGKTTTINSLIKVFEKLELKMLLAAPTGRASKRMTEATGKE SKTIHRLLELGFGDDREGMLFQRNEDNPLDCHVIIIDEVSMVDIILMNSLMKSIARGT RVVLVGDVDQLPSVGAGNVLRDIIDSKVVKTIRLTEIFRQAQESMIVVNAHRINQGLY PQLNEKQKDFYFMKRNAKEDVLATVVELVRDRLPKHYQFDALRDIQVLTPMKKGETGT LNLNKELQAALNPPNVSKAEKDLKEKIFREGDKVMQIKNNYTLKWRCLDPMAEEQKGE GVFNGDIGYVQSIDTEAEELVILFDDQKQVNYSFTQLDELELAYSVTIHKSQGSEFPV VVIPITWGPPMLLTRNLLYTAVTRARSLVVLVGVESYLKKMVDNNKIIERYSGLGRRL GKYFEMQIKDETKI" gene 10723..11451 /gene="" /locus_tag="" /db_xref="771594..772322" CDS 10723..11451 /gene="" /product="phosphoribosyltransferase" /translation="MKAYWGALMDLMYPLDVSCIACKENLSNQTKYYLCDTCYGEIDF FPEHCCHQCGKILSMTEAVGLCQACESKPPSFERAIAVFQYQGHIKRLIFRFKYEHEP YLSRIMGQMLADSYEKEALEVGLIIPVPLHYKRQKQRGFNQAELLAKYMSQQVKQPYD PDVLIRSQETIIMHHLTRQQREENVKQAFMVKNPGLIVNQKLLLIDDIVTTGATLKAC SRVLLEAGAQSVTALTLARGGGQS" gene 11469..11882 /gene="" /locus_tag="" /db_xref="772340..772753" CDS 11469..11882 /gene="" /product="flagellar protein" /translation="MDLRNCKQCGRAFSYQGMEVCSRCASDDQSEFAKVKEYLYEHPG ATVSEVSDETEVSEKSILRYLRESRIEIRESDNLYLDCERCGAGIQSGKYCDSCAGEM KRQFTAAITPKTKPKEETTTESKNRMFIAERKRQK" gene 11956..12249 /gene="" /locus_tag="" /db_xref="772827..773120" CDS 11956..12249 /gene="" /product="anti-sigma-28 factor, FlgM family protein" /translation="MKIHSNPNVIQAMKVYNKTATEKIQKGQSVHQPKDEIEISTKGK EFQVALKAFNALPEIREEKVKLVKEQMEQGSYSVSGKEVADKMIDGLMIDHKI" gene 12281..12775 /gene="" /locus_tag="" /db_xref="773152..773646" CDS 12281..12775 /gene="" /product="hypothetical protein" /translation="MSKSIEQLKEALIQENKMYEAVLEMAEEKTEVIVQGQVKELEKI TELEQQYMAKMGAFEKVRRSIFANMSEELGIKEPTSVSELLLFLKEPVGEEIDTLRNN LLETIEGLTKVNERNEKLIHQSLEYIHFNLKIMTDSNGDGNEYGHKANEKQKTKTNFF DMRV" gene 12792..14273 /gene="" /locus_tag="" /db_xref="773663..775144" CDS 12792..14273 /gene="" /product="flagellar hook-associated protein FlgK" /translation="MRSTFSGFNTATSGIFASQRSLDVVGHNIANANTPGYSRQRLEQ AASTPMSLYGGKGMLGTGVDTVAIKQMRSEFLDFKYRDEVNALGYWETKEYGLEFIES IFNEPSDTSVATVTDELFAGFEELSKNPESITARTVVRERGIAFTNTMNQTYKQLEKL AKDVNSDINATVSSINSYADQIAELNKQIYRFEADGSSANDLRDRRNLLIDDLSKLVN VEVRDVNDGYGSSKMVVQINGQPLVNHDQAYKLDATATKSSTFDDEINMTEIKWANGS VVNQDSLKGELGALLTLRDGTTKDNKGIPFYIEQLNDFVGSFAKAVNGIHEDGLDLDG DEGVAFFTDGNTGDQITAKNIQISLEIDRDPRKIAAATMGELGEPVVGDGSNALRLTE LRHAQMSFDNGEFKGTPEDFMISLIANLGVNTQEATRMASNQSILTNQIDRQRQSISG VSLDEEMANMVRFQHAYNASARMVTTMDEMIDVIINRMGTVGR" gene 14319..15275 /gene="" /locus_tag="" /db_xref="775190..776146" CDS 14319..15275 /gene="" /product="flagellar hook-associated protein 3" /translation="MRITNNMMISSMMQNLNGNLLRMDQKQLQATTGKRIHKPSDDPI GISRSLKLRSDIKELEQYKKNVDDTISWLETTELAVHNVGAAVERLRELTVQASNGVL TEDETKKIKAEVVELKNQIISLGNTTYGGKYVFSGKKTDQKLFNDAGEYNVSNLSIDH APDAIDDKIKFNVGMGETIEINVVGFELFGGDEVSHEDDVVGVEGGEQAGIIKMIEDI EAKLEAGDTAGLTDDLQNIDIYYDQYSTIRSEIGAKVNRMELVENRIVDDRLNLMELQ SKIEDADVAEVYMQLMAEENVYRSSLAIGSRIIQPTLMDFLR" gene 15316..15879 /gene="" /locus_tag="" /db_xref="776187..776750" CDS 15316..15879 /gene="" /product="hypothetical protein" /translation="MNLRIDMQNAQIGIQQQMGQLNIQQNHFPMTLQQTEPKLSLQTA DAELTIDQQRCFAEVGLKNDRQLTATYAQKGNRTAQQAIARIAQEGKQMANIQNGKVI ARQAKQSQGTQQRQLNYDMAPKSRPDINVTPKEVQINFQKGEVSVNVQNPGAQIDYQQ GDLQVYLKQKDFINIEYIGQNLNTLGG" gene 16088..16576 /gene="" /locus_tag="" /db_xref="776959..777447" CDS 16088..16576 /gene="" /product="flagellar assembly protein FliW" /translation="MILQTKHFGEIEINQEEIIRFPDGIPGFDDYTQYIFIENPDKEV PFHWLQAVEDGALAFVITNPFLFKPDYDFEISKNVVEKLSIEDQSDLQVYTIVRVPEN IKEMTANLRAPLVINTKNKKGKQLMLDSEVYHTKHYILEEIQKMQEQSNQTSPAAEGG RD" gene 16576..16803 /gene="" /locus_tag="" /db_xref="777447..777674" CDS 16576..16803 /gene="" /product="carbon storage regulator" /translation="MLVLSRKNNESIMLGKDIEIKILGIEDGKVKLGIEAPKDVEIYR KEIYLEIQEENKAASEQKQDWSQLKGLFTKK" gene 16985..18184 /gene="" /locus_tag="" /db_xref="777856..779055" CDS 16985..18184 /gene="" /product="flagellin domain-containing protein" /translation="MRINNNLMAMNTHRQLGSAQANGAKSMEKLSSGFRINRAGDDAA GLSISEKMRGQIRGLDQASRNAQDGISLIQTAEGALNETHSILQRMRELSVQSSNDTN VQEDRDALQAEMDQLATEITRIADNTEFNTKNLLGGEFEGKFHIGANEGQNMELKIAA MDADSLKVQGEVYEAQDLDNVDNVQIQSRTGEDVTVEFAAIQVADGAAVTSTTAAWNT DGDVLTVTLAQAAPTSTGSTGLVQASDQDIMNAINAAGGEYGLSAIANGTVSGTAITN GSAGIADVDLNNWELDVEASAASGIDISSQAKADEAITTINTALERVSKERSMLGAVQ NRLEHTISNLDNVSENLQASESRVRDVDMAKEMMELTKQNILQQASTAMLAQANQAPQ SVLQLLG" ORIGIN 1 atgaacaaaa ggatgctcag tttatttgtc atgatacttc taacggtcca gtgggtgaca 61 gttggggtgc aagtaaatgc agcaaaccct agtcatgaac aaattaaaga aatcattgaa 121 gaggtggccc tggaaaaaaa tatcccggct gtgatattaa aggcaattgc agacaaggaa 181 agtaaattcc gacaatttac tgatagcggg gcgccctttg taagtaatgg aaatacaggg 241 attatgcagg tgaatcgagt tcaccacgga acctatgatg tccagcgatt aagggaagat 301 ctgcgttaca acatagaagc tggggcagat atattacaaa gtaaatggga ttggagtgtt 361 gtccctacaa ttggagatgg ggatcctaat attgttgaaa actggtattt cgcattgtgg 421 gcatataatt cgtgggatgg cagaaataac ccaaatatac atggtagtgg cgtatatcaa 481 gaggagctat tacagctggt aagggaaaag tacaatcaac ccgttacttc tattgattgg 541 agtttgattc ctagaagtgg cacaccatca ggaggaacac aagttgcaac ccctgaaaaa 601 catcactatg ctgtggcaga agagaagaag gaagaaaaga tttttgtggt cacacgctct 661 ggtggaaatc gctccatctt tagagatgta gcggatcatc aacaagaaat gtacatagag 721 tcaattgtaa aagaagaaat tatgtccggt gtgggacaag aactttttaa gcccgatgat 781 ctcattaccc gtgaacaagt agctaaagtc attgtagatg cattggactt agaagtggtg 841 gatgaaacaa tggcggtatc taaaatagtt gactggcatg aagtatctgg atgggctcga 901 gactttatgt caatagttta tcaactggaa attatgactg gatatgagga tggcacattg 961 aggccaagtg atttcgtcac ccgagaacaa gcggcagtga ttttagcaag tggattaaat 1021 acaaatacga tgatcatgac agctgagccc tatgaggatc aagaaaaaat cagcccttgg 1081 gccatagaca gcatcaatga attaaaaaca ttgggaatat tgcaaagaga taacaggcta 1141 cgacctaagg attatatcac ccgggctgag tttagtaagt ggatttatta tctcctgcga 1201 tatgacagtg atgcattaag acttcagtaa tttgttgcgc taaatccatg attaagctga 1261 gtcggatatg gtgaatggtt gaattgattt tctcatcgtt tggagcaaca attccgatta 1321 gtgaaagatc accaacagaa ggtagggctt tacccacacc cttgcctgga gcaatgggac 1381 ctgggcggag cgttatgaat cccacctgtt cactgtcacc aaggcttgcg tcgatggcta 1441 gaataaaagc atttggatgt ttctgtttga gcatcgtaat tgtgtttttg aggttcaaag 1501 catgaatagg ctgacccaga gtgccataaa tgagatgtgg aaagtgcttc tgtaatagaa 1561 gactacccac taaaggacct agggcatcgc cgatacagcg atcggtaccg atacaaagga 1621 caataaattc atcagggaga ttcagggata aatagcggac aaactgagga atcatctgtg 1681 gatttttata atgatagcta accaaaagaa acacccccta tatatgttat atatataggg 1741 ggtgtttgca atttatgact aaaggagggg gaatagctta ttcattattc aatagataat 1801 attctacaat caattcatca agctcttgac tcaaatccac aatgtcatag gtggccctac 1861 cttcatctaa tgagcgacta agttgttctt taagttcttc gatgcgatct tttaaattat 1921 taatatgatt cacctagtat cactccattc ttatggttaa gagcacctac ggtggacttg 1981 gaacccgcat accaatattt tactggaatg gtacgcttgt ccatattata ccactaaata 2041 aagggattaa acattacgtg gagattacca taatattaaa taagtattac agaaacttaa 2101 agtagatgcc tagggaaaaa cagtggtaaa ttaaatagaa aacagaacat aaaaaaacaa 2161 aatataggac taggacaagt ctctcaatga taaaatataa tggagagatt gaggtgaaaa 2221 aatggagagt gcttttcagt ggatgacaaa ggagttgatg gttcttttta ttgcggctct 2281 gccaattatg gagctaaggg gagcgattcc cataggggtt tccatgggaa tacatccatt 2341 acacgccaca attttagggg ttgtggggag tttactacca gtgccttttt tattattatt 2401 cctagagccg gtttttgaaa aactaaaaaa gtccaagttt tttttcaagt ttattcaacg 2461 tactgtgaaa aaaaccagga agagcagtga aagaattcga aaatatagta cattaggact 2521 ggtactgttt gtggcaatac ccttgcctac cactggggta tggagtgggt gcttggcggc 2581 aaaactattg gcggttccat ttaagtatgc catgcctgcc atcgcagtag gagcctccat 2641 tgctggtacg attatgttta ttctgagtta tattgcaata aaaatctaat ccagtcttca 2701 agtgaagttt catatatgta aaaaaaatgt tgacatatat aaaacccaat ggtattatgt 2761 tttcagtgag aaattaaata gaaatcttga tgccttatca agagtgatgg aggggaaggg 2821 cccgatgaaa tccggcaacc atagagtgta tggtgctaag tccctcagaa ttttggttct 2881 gaaagatgag gaaatattga aagacaaccc tcttctgatg agcccatcat attaagaggg 2941 ttttaatttt ttatatagtt tcagttgagt cgggtatatt aatagggact tgcgaaagcc 3001 taaggacagg gtatatgaat aggctacata gacaacaaag aaacaaagaa atagaggagg 3061 cttataaatg ggaaaaagat tatttacttc agagtctgtt acagagggac atccagataa 3121 gatctgcgat caaatttcag atgctgtatt agatgcgatt ttcgagaagg atccaaaggc 3181 aagagttgct tgtgaaacaa gtgtgtccac aggacttgta ttagtggcag gagaaattac 3241 aactgattgt tatgtggaca tccctaaggt ggttcgtaga accattgcgg aaattggcta 3301 cacccgtgca aagtttggat ttgacagtga cacatgcgct gtattaactg ccatcaatga 3361 gcagtcacct gacattgccc aaggtgtaaa tgaagcctta gaaaatagag ctggagaagt 3421 gaccgatggg ctagagtcca tcggtgctgg agaccaagga atcatgtttg gatttgcctg 3481 caacgaaaca cctgaattaa tgcccttacc gatttcatta gcccataagc tagcaaagcg 3541 cttatcagat gtcagaaaga acgggacctt ggattactta agacctgatg gaaaaacaca 3601 ggtaactgta gaatatgatg gagataaacc caaaagagtg gacaccattg ttatttctac 3661 acagcatagc cctgaagtag atcacaaaac aattgagaga gacttaatcg agtatgtcat 3721 caacaacatt gtaccagcgg aattaattga tgcaaaaaca agatatttaa ttaatccaac 3781 tggacgattt gtcgtgggtg gaccccaagg agatgcgggc ttaaccggta gaaaaattat 3841 tgtagatacc tatggtggat atgcccgtca tggcggaggt gctttctcgg ggaaagatcc 3901 aacaaaggta gacagatcag ctgcctatgc tgctagatat gtagcgaaaa acattgttgc 3961 cgcaggccta gctgataaat gtgaaattga gctggcctat gccattggag tggcgcaacc 4021 ggtatctatt ttagttgaaa catttggaac aggaaaagta gatgaagaca agatgatcga 4081 acttgtccac aaatattttg acctaagacc agctgccatc attagagact tagacctaag 4141 aagaccaatt tatcgccaaa ttgcagccta tggacacttt ggacgtaccg atgtagattt 4201 accatgggaa agaactgata aggctgaagc cttgagagca gaagtacttt aattaagaca 4261 tacaagtaaa aagcttattt cctttagtga ttcacagagg aaataagctt tttttcgtga 4321 tttaaactta ttccataagg aatgccactg aatcagtagg ggaataagcc ccgttctctc 4381 ttcgccaaaa actcactgca gcgctacaat agaactaccg gtaatacttg aaggtgcacc 4441 ttccaaaagg aagggttaaa gtgaatcaag attttgaagc aagggtgttg gaggcaaagg 4501 caggaaacag acaggcaaag gaatggattg tttttaaatt aaatccctta gtgatctcac 4561 acagtggtag atatggagga tgtaaaggat atgatgagga tgccattcag gatggtcgta 4621 tgaagatact agaagcaata gagaccttcg atttagaaaa gggtgttccg tttttgggct 4681 atgttgcatt agctgtacaa cacttttatc aaaacaggag aaggaaacag cgaattcatc 4741 tatccctgga ttcgcctata ggaaatggag ttgaagaaga aaatgggact tggattgacc 4801 tgattgtaga tgagtcagta gagattgaag aagatctcat tagaaaagag acccatcaat 4861 ggatacatga aaatatgagt tgtttaagcc aaggtcagca acaggtggtg agggactttt 4921 attttaataa acattcttta aaaacaattg cagccaaaag aggggtacat cccattactg 4981 tggcaaagac aaaggggctg gcattaagga agttaagacg tcaggctacg taaaaactca 5041 ttttctcttg attttgtcat tctgaacaca gtgaagaatc ttgaatttta aaccttcaag 5101 acccattcgc tacgctcagg gtgacaattc ttacgcagtc tgacgtctcc tagagatgta 5161 atttcatgaa aaaagctaag gtaacttctg gggatgtaaa taaagggtga tttggtagaa 5221 ttaacaatag tttgatttat cttaattgac agatataact atgtctaata taattacact 5281 ggcgtttacg acaaaaattg acaaatattt accaatttct acattttatc aaaagaagca 5341 tcgtctgtga atgcaacatt cataaatttt atgtaaagga gcttacatta tggaaagtac 5401 aaaaaacgta aaaagaatca gaaaaggctc aatcaagatg aagctagttg tgataccatt 5461 aattgtatca ttattagctg taggtgccat tggttttctt tctacacatt tcactagaga 5521 cagtatgcta gaacagatga gagaagatgg gttttataca gcggaacggt tgataggaag 5581 gatagaggac aataatgact ccttggaaag catggatgaa gtactagagg atcaaatcag 5641 aggggtagct aatgttgtca tgggaaacag agcaattatc agcaatgagt atttggtgga 5701 gctagcagca caattagatg tacatagaat tcactattgg tctactgata ccatgaaaat 5761 cgcatatact gcaaccgatg gttttgtggg tctagatgcc ccagtggaac atgtactaca 5821 tgattttcac gccagtggtg ctgctgaaat catggaagaa gcaagacaaa gtgcagagac 5881 aaatgaatcc tttaaatttg gctatgtaaa aacaccagat ggggatgtta tacaggtggg 5941 gatctccgct gatcgcatcc atgagctaac ggaaaactta agttatcaaa gtttggtaga 6001 ggatttagct gacaatgaga aagtcgttta tgcactcttt atagatagaa acctagaggc 6061 ccaggcccat agtaatcggg agcgaatcgg aatcgagctt gacgatgaag gtagtatcgc 6121 agcagcagta aatggggagt cctacgcttg ggagtatttc tatgaggcag cagatttgaa 6181 tgtatatgat gttttactgc ccattgagat tgaaggacag catctgggtg ccattaacat 6241 cggattttcc atggcggagg ttgattcagc aatcagtaga aatataatga tggttgcaat 6301 tacaggtatt gttgcattta ttatccttgg gatggtactt ttcaccctat ctaatgatgc 6361 agtaaaaaca ttaaataagc taaaggatca aatggcattg atgggtaacg gcgacttcac 6421 taaggatgtg tctcaggata tcatcaataa aaatgatgaa tttggagaaa ttggccatgc 6481 cataaaaagc atgcaaacca ccatcaaagc aatgattagc aacatagcca acacctccca 6541 gcagctggcg tcttcctcgg aggagctaac cgccaccagt caacagtctg ccaccgcagc 6601 agatgaagtg gctaaaacaa tcgaggaaat cgctggaagt gcaaatgagc aagcaaagga 6661 cacggagaat ggtgttttaa aaacagatga actcagtaag attatagaag aagatttaaa 6721 ggatatggaa gaaataaata acaccataga acagttaacc atcctaaagg atgatgggat 6781 tggaatcgta aaagaattaa ccaataaaac aaacaatagt gatcaagcca tcaagacaat 6841 ttatcaaagt actgtggata caaatgaaag tgcagaaaga attggagaag ccagcaaaat 6901 cattgaagga attgcagagc aaactaattt gttagcccta aatgcggcta tagaagctgc 6961 aagagcagga gaagcgggta aaggctttgc cgtagtggct gaagaaatcc gtaagctagc 7021 tgaacaatct acagtttccg taaatgagat cgatgagatg ctgaaaaagc tacagagtaa 7081 ctctcaaagt gctgtaaatg tgatggagac cgtgctatct accattaaag agcaagtaga 7141 gagtgtttcc atgacagagg gtaagtttga cgggattgct gagcaagtag agcgtgtcag 7201 agcagttgtg aagaagtcaa cggactccgt caacgtaatg aacctcacaa aggatgaatt 7261 ggcaaatatc atgcagagct tggccgccgt tgcagaggaa aatgcagcgg gaacagagga 7321 agcctctgct tcagtggagg agcaaacagc ctctatggaa gaaatagcta gttcaagcga 7381 gtcattggct cgattggcag aagatatgca agagagtatt agtaaattta attattaaaa 7441 aacaaagaga ttcttaggat tcacaggaat aagcttattt ccttttgcaa cttgcaaaag 7501 aagtaagctt ttcttctgtt ttaaatccca ttgaaaggct tattagaaca aagataagag 7561 gtcctcaata aaaaaattca aaaatcaatg ctaacttttc ctttcttacg acagttacta 7621 agtaagaagg gaggtgagca ggatgccaat caatattatg aatgaaacct caagagtaag 7681 acttcgtttt gtagatcgaa ttgatgaaga ggggagagaa cgattagtca caagaaccta 7741 cagcaatgtg aagcctgagg ctgccgatga agctctctac aatgcttcag caaccattgt 7801 gggacttcaa agcaagccac tgaaaaccat cattcgagca gatgaaaagg agttagtgga 7861 gtaatctatc cttaggatag aaataaggag gtgaactaga tgaatcaggt attagcgtta 7921 tcctttatga agggtgatgg cacaaagcta agaatgacag tgccacatcc aagggaagat 7981 gtaacagggg cagaagtgaa aactgccatg gatgaaatca tcgcaagtga tgtctttgct 8041 cccggtggaa ttgccttgac tggtgttgat gaagcgagaa ttatttcaac ccaggaggat 8101 gtattggagt tagtataatt aggagccgag ggagattttc ctcggctttt acattgttgt 8161 agagggggtg agaaaaaatg aatgatgtat tcggtcatgt ggccaacctg ggattcccca 8221 tcgttgtgtc ggtgtattta ttggtgcaaa tcgaggagaa actagaagga cttaccgtga 8281 gtattcatga attagccaag tctattgagc gattaacaat gaaaagaccc gagggattgt 8341 gatataatgg aaggcaagaa tgcgtgtaac aggaggaagt gctgtggttg agctagaagg 8401 acagttagtg gaaatcattt ttcaaaatga atccaatgga tatatggtag ggattttaga 8461 ggcaaaagaa gagatcgcca caattgtagg ctgtttgcct gccattaaag aaggagaaca 8521 attggctgta aaggggaaat gggcggtgca tcctgtctac ggcagacagc tagaggtagg 8581 ggaataccgt cccattcaac cctccacaaa ggaagggatc ttaaattact tatcctcagg 8641 agtcatcaaa ggcgtgggaa aaaagatggc ggagcgaatt gtggatctat ttggaatgga 8701 ttctttggag gtgattcaat atgccccaga acgattgagg gaggtagagg gtattgggcg 8761 agctaaggcg gagaccatca ccgagacctt tagggatcaa aaggagctca gggaaatcat 8821 tctctttctt tcggagtatc atatcacccc taattatgca gtaaagatac ataaaaagta 8881 tggagataaa accatcgcca ctattcaaga aaatccctat cggttggcgg atgaaattgt 8941 tgggattggt tttaaaagag ccgatgccat agctcgaaat atgggggttc atccccattc 9001 aaaataccga attcattcag gaattaaata tatgttaaac acattccaag gggaaggtca 9061 tacctatgca ccgggtgtta agctaatcca acgggcagag gagctactca gggtagaaga 9121 aggtcaggta gaaggcgcca tccaagagct tgccctgaat caggaaatac aattagaacg 9181 aattgatgat gagattatcg tttattctat gccctattat tatgcagagt ctaatgtatg 9241 taaaaagctc atcagtttag ctcaagtaga gttagacccc atcgaaatgg atattgacga 9301 agaactacag aagattgaac aagcagaaga gatgacactg gcaaagcaac aaaaagaagc 9361 catcaaagaa gcaatcgaga atggaatttc agtcattact ggaggtccgg gaacaggaaa 9421 gacaacaacc atcaatagtc tgattaaggt tttcgaaaag ttagagttaa agatgctatt 9481 ggcagccccc acaggcagag cctctaaaag aatgacagag gccactggaa aagaatcaaa 9541 aaccattcac cggttattgg aattgggatt tggagatgac cgtgaaggca tgctttttca 9601 acgaaatgaa gataatcccc tagattgtca tgtcatcatc attgatgaag tgtccatggt 9661 ggatattata ttaatgaata gcctaatgaa gtccattgct agggggactc gggttgtatt 9721 agtaggagat gtagatcagc ttccctctgt gggtgctgga aatgtacttc gagacattat 9781 tgacagcaag gttgtgaaga ccattcgact aacggaaatt ttccgtcaag cccaggagag 9841 catgattgtc gtcaatgccc atcgaatcaa ccaggggctc tatccacaat taaatgaaaa 9901 gcaaaaggat ttttatttta tgaaacgaaa tgccaaggag gatgttttag ccaccgtagt 9961 ggaattggtg agagaccgac ttcctaagca ctatcagttt gacgccctac gtgatattca 10021 agtgctgaca cccatgaaaa agggggagac tggaacacta aatctgaaca aagagcttca 10081 ggcagctttg aatcctccaa atgtatccaa ggcagagaag gatctcaagg aaaagatctt 10141 ccgagaggga gacaaggtaa tgcaaattaa aaataactat acattaaagt ggcgctgtct 10201 agatcccatg gctgaagaac aaaaggggga gggtgtcttc aatggagata ttggatatgt 10261 ccaaagcatc gatacagagg cggaagagtt ggtcatacta tttgatgacc aaaaacaagt 10321 caactacagc tttacccagc tagatgaatt ggaactggcc tactccgtca ccatccacaa 10381 aagtcaagga agtgagtttc ccgttgtagt cattcccatt acatggggac cccctatgtt 10441 attaactcga aatctactct acaccgcagt aacccgagcc agatccctgg tggtattggt 10501 cggggtggaa agctatttaa aaaaaatggt ggacaacaat aaaattattg agcggtactc 10561 tggactaggg agacgtttgg ggaaatactt tgaaatgcag attaaggatg aaactaaaat 10621 ttgaatatga ttatccagaa tcaatgtact gagactatag atgcatttct taattaattt 10681 tgtcgaaaaa gcaggaaaaa aatatttcaa ggagaaataa agatgaaagc atattggggg 10741 gccttaatgg atctaatgta tccattggat gtcagctgca ttgcatgtaa agaaaaccta 10801 tcaaatcaga caaagtatta tttgtgcgat acctgttatg gtgaaattga tttttttcca 10861 gagcactgct gtcatcaatg cggtaagatc ctttcaatga ccgaggcagt tggtctatgc 10921 caagcctgtg aaagcaaacc gccttccttt gaaagagcaa tcgctgtgtt tcaataccag 10981 gggcatatca agcgtctcat ctttcgattt aaatacgaac atgaacccta tctcagtcgc 11041 atcatggggc agatgctagc tgatagctat gaaaaagaag ccttagaggt tggtttaatc 11101 atcccagtgc cattgcatta taaaagacaa aaacagcggg gatttaacca agctgagctc 11161 ctagctaaat atatgagtca acaggtgaag cagccctatg atccagatgt actcatacgt 11221 agtcaggaaa ccatcatcat gcatcatttg acaagacaac aacgggagga aaatgtgaaa 11281 caagcattta tggtaaagaa ccctgggtta atcgtaaacc aaaagctctt attaattgat 11341 gatatcgtga ccaccggggc gacgttgaag gcctgtagcc gagtgctgtt agaggcaggg 11401 gcacaatctg taacagcttt gactttggca cgaggtgggg gacaatccta gagaaggagg 11461 aataaagaat ggatttaaga aattgcaaac aatgtgggag agccttttct tatcagggca 11521 tggaagtttg ttcccgatgc gcaagcgatg atcaatcaga atttgctaaa gtgaaggagt 11581 atttatatga gcatcctgga gccactgtgt cggaggtttc tgatgaaaca gaggtaagtg 11641 agaagagtat cctgcgttat ttacgtgaga gtcgtatcga aatccgggag tcagataact 11701 tgtacttaga ttgcgaacga tgtggagcag gcattcaatc aggaaaatac tgcgattcct 11761 gtgctggtga aatgaaacgc cagttcactg cagctattac accaaaaaca aagcctaagg 11821 aagaaacgac cacagagtca aaaaatagaa tgttcatagc agaaagaaaa agacaaaaat 11881 aacttaagaa aaccctcact ttagccgata ctatatgtga aagaaggaaa tcggaaaaag 11941 tcgaggtgtt tttttatgaa aattcacagt aatccaaatg tcatccaggc catgaaggta 12001 tataataaaa cggccactga aaagattcaa aagggacaat cggtacacca gccaaaggat 12061 gaaattgaaa tttccactaa gggaaaggaa tttcaagtgg cattaaaggc ctttaatgca 12121 ttgcctgaaa ttcgagaaga aaaggtaaag ctggttaagg aacaaatgga acaagggagc 12181 tacagcgttt ctggtaaaga ggtagcagat aaaatgattg atggactaat gattgaccac 12241 aaaatttaag cgtaagctga agacgatcga ggtgaatggg atgagtaaat ccatagaaca 12301 gttaaaagaa gctttaatac aagagaacaa aatgtatgag gcggttttag aaatggcaga 12361 agagaaaaca gaagtcattg tacagggtca ggtgaaagag ctagaaaaaa ttacagaact 12421 tgaacagcaa tacatggcaa aaatgggcgc atttgaaaaa gtgaggcgtt cgatttttgc 12481 taacatgagt gaagaattag ggatcaaaga gcctaccagt gtttcagagc tactgctatt 12541 tctaaaggaa cctgttgggg aggaaattga caccctaaga aacaacctgt tagaaaccat 12601 agaaggatta acaaaggtga acgaaagaaa tgaaaagctc attcatcaaa gcttagaata 12661 tattcatttt aatttaaaaa taatgaccga ctccaatgga gacggcaatg aatacggtca 12721 taaagcaaat gaaaaacaaa aaacaaaaac aaacttcttt gatatgaggg tatagaaaag 12781 gtgggaaaag aatgcgttca acattttcgg gatttaatac agccacatca ggaatttttg 12841 catcacagcg gtctttagat gtagtaggac ataatattgc aaacgcaaat acaccgggat 12901 attcaagaca acgactagaa caagctgcca gtacccccat gagtctatat ggtggaaaag 12961 gaatgctggg aactggtgtg gataccgtag ctatcaaaca aatgcgaagt gaatttctag 13021 attttaaata tagagatgaa gtaaatgcat taggatattg ggaaacaaag gagtatggac 13081 ttgagtttat tgagagtatt ttcaatgaac catctgatac aagtgttgcc actgttactg 13141 atgaactttt tgctgggttt gaagaactga gcaaaaaccc tgagagcatc actgcaagaa 13201 ccgtagttcg agaacgggga atcgctttta ccaacacaat gaaccaaacc tataagcaac 13261 tagagaaatt agctaaggac gtgaattctg atattaatgc cactgtaagt agcattaaca 13321 gctatgcaga tcagattgct gagctaaata agcaaattta tcgattcgaa gcagatggta 13381 gtagtgctaa tgatttaaga gatcgaagga atttactgat cgatgatttg tctaagcttg 13441 taaatgtaga ggtgcgagat gtaaatgatg gatatggttc atctaaaatg gttgtgcaaa 13501 taaatggaca acccttggta aatcatgatc aagcctataa attagatgcc accgcgacaa 13561 aatccagtac atttgatgat gaaattaaca tgactgaaat caaatgggcc aatggcagtg 13621 tggttaacca agattcatta aagggagaat taggggcttt attgacttta agagatggaa 13681 caaccaagga taataaagga attcctttct atattgagca gcttaatgat tttgtcggga 13741 gttttgcaaa agcagttaat ggtattcatg aagacggact cgacttagat ggagatgaag 13801 gcgtagcatt ttttacagat ggcaataccg gagatcaaat tacagcaaaa aatattcaaa 13861 tctccttgga gattgatcgg gatcctagga agattgctgc cgccaccatg ggggaacttg 13921 gggaaccagt agtaggagat ggatccaacg ctttaaggtt gacagagcta cgacatgctc 13981 aaatgagttt cgataacggt gagtttaaag gaacaccaga ggattttatg atttccttaa 14041 ttgccaactt aggggtaaat acccaagagg ctacgagaat ggctagcaac caaagtatat 14101 taacaaacca gatagatcga caacggcaat caatttcagg tgtttcctta gatgaagaaa 14161 tggccaacat ggttcgtttt caacatgctt acaatgcctc agccagaatg gtcacaacca 14221 tggacgaaat gattgacgtg attattaatc gaatgggcac tgtgggtaga taaaacgctt 14281 aaaatatgat cgatatatga tagaaggtgg agaagctcat gaggattacc aataacatga 14341 tgattagtag tatgatgcaa aatctaaatg gaaatttact tcgtatggat cagaaacaac 14401 tacaggcgac tactggaaaa cgcattcaca agccctctga tgatcctatc ggtatttcca 14461 gaagtttgaa gctacgttcg gatatcaaag aactagaaca gtacaaaaaa aatgtagatg 14521 acaccatttc ttggctagag accacagaac tagcggtaca taatgtaggt gcagccgtag 14581 aacgactaag agagctgacg gtgcaggctt ccaatggggt attgactgaa gacgaaacaa 14641 aaaaaattaa ggcagaagta gtagagctaa agaatcaaat tattagtctg ggaaacacaa 14701 cctatggcgg aaaatatgtt ttttccggaa aaaaaacgga tcaaaagctt tttaatgatg 14761 ctggagagta taatgtaagt aatttatcaa tcgatcacgc tcctgacgca atagatgata 14821 aaatcaaatt taatgtaggt atgggagaaa cgattgaaat caatgtagta ggatttgaac 14881 tcttcggtgg agatgaagta tcacatgaag atgatgtggt aggggtagag ggtggtgaac 14941 aagcaggaat tattaaaatg attgaagaca tcgaagcaaa attagaggcc ggggatactg 15001 ctggtctaac ggatgacctt caaaacatag acatctacta cgatcaatat tcaaccatac 15061 gatcagaaat tggagccaaa gtaaaccgca tggaattggt tgaaaatcga attgtagatg 15121 atcgcctaaa cttgatggaa cttcaatcta aaatagaaga tgcggatgtg gctgaagtgt 15181 acatgcagct tatggcggag gagaatgtgt atcgttcttc attggctatt ggctcaagga 15241 ttattcagcc gacattgatg gatttcttaa gataaaaaga caaaagaagg tcttaaaaaa 15301 ccaggagggg atgaaatgaa tctccgaatt gatatgcaaa atgctcaaat tggaatccag 15361 caacaaatgg gacagctaaa cattcaacaa aatcattttc ctatgacatt acagcaaaca 15421 gagcctaaat tgagtctaca aacagctgat gcagagttaa ccattgacca acagcgatgt 15481 tttgcagagg ttgggctaaa aaatgaccgg caattgacgg caacctatgc acaaaaagga 15541 aatcgcacag cacaacaagc tatagctcga attgcccaag aaggaaaaca aatggcaaat 15601 attcaaaatg gtaaggtcat tgcacgacag gcaaagcagt cacagggaac gcaacaaaga 15661 caactgaact atgacatggc acccaaaagt cgtcctgata tcaatgtgac cccaaaggaa 15721 gttcaaatta actttcaaaa gggtgaagta tcagtgaatg tccaaaaccc aggagcccaa 15781 atagactacc agcaagggga tctacaggtc tatttaaaac agaaagactt tattaatatc 15841 gaatatatcg gacagaattt aaatacgcta ggggggtaag gggatgaagc ccttgccttt 15901 ttactttcta ataaacgatt aatctataaa acttttatag gcgttaacgt aatcaaatca 15961 tttccagaaa tcctttcaaa gtgtcatcct gagcatagtg aaggatcttg caataaaatg 16021 acaaattata gcttaagtta acgctaacgc taacgctaac gctttaaaac atagaggagg 16081 aaaaagaatg atattacaaa caaagcactt cggtgagatt gaaataaacc aagaagaaat 16141 tatcagattt ccagatggca tcccaggttt tgatgactac acacaatata tctttattga 16201 aaaccctgat aaggaagtgc cctttcattg gctacaggct gtggaggatg gggcactggc 16261 ctttgtcatc accaaccctt ttttatttaa gcctgattat gactttgaaa tctcaaaaaa 16321 tgtggtagaa aagcttagca tagaggacca atcagattta caggtgtaca ctatcgttcg 16381 tgtcccagaa aatataaaag aaatgacagc gaatctgagg gcacctctag ttattaacac 16441 taaaaacaaa aaaggaaaac aactgatgct agacagtgaa gtttatcata caaagcatta 16501 catattagaa gagatccaaa agatgcagga acaatctaac caaacatctc cagcagcaga 16561 gggaggtcga gactaatgct agtcctatca agaaaaaaca atgaaagtat tatgctaggc 16621 aaagacattg aaataaagat cctgggcatt gaagacggaa aagtaaaact agggatagaa 16681 gcccccaagg atgtagaaat ctatcgcaaa gaaatttacc tagaaatcca agaagaaaac 16741 aaagcagcca gtgaacaaaa acaagactgg agtcaattga agggattgtt tacaaaaaaa 16801 taaaaaaaga caaagttttt tcattttccc tatcaagttc tatattttta aaccgataac 16861 tataataaga acaaaaactt ctgatttctt acacgccggc aaaaagaaaa agaagttgga 16921 gtatacttag tgatcttatg gcaaggatgc caaagacata ataaaattca aggaggaata 16981 acaaatgaga attaataata acttaatggc aatgaacaca catcgtcagt tgggtagtgc 17041 acaagcaaat ggtgcaaagt caatggaaaa attatcttca ggctttagaa tcaacagagc 17101 tggagacgat gcagcaggtc tttctatcag tgaaaagatg agaggacaga ttcgtggttt 17161 agatcaagct tctagaaatg cacaagatgg tatttcttta attcaaacag cagagggtgc 17221 tttaaacgag actcactcta ttctacaaag aatgagagaa ttatcagtac aatcttccaa 17281 tgatacaaac gtgcaagaag accgtgatgc actacaagct gaaatggatc aattagcaac 17341 agaaatcaca agaattgctg ataacacaga gtttaataca aaaaacctat taggtggaga 17401 gtttgaagga aaattccata ttggagctaa cgaaggacaa aacatggaat taaagattgc 17461 agcgatggat gcagattctt taaaagtgca aggtgaagta tatgaagcac aagaccttga 17521 taatgtagat aatgtacaaa ttcaaagtag aacgggagaa gatgtaacag ttgagtttgc 17581 agctatacaa gtggctgatg gtgctgctgt aacgagcaca acagcagcat ggaatactga 17641 tggagatgta cttacggtta ctttagctca agcagcacca acgtctactg gatctactgg 17701 tcttgttcaa gcaagtgatc aagatattat gaatgccatc aatgcggctg gaggagagta 17761 tggtctttct gcaatagcca atggaaccgt tagtggaact gctataacaa atggttcagc 17821 tggtatagcc gatgtagatt tgaataactg ggaattagac gtggaagcat cagcagctag 17881 tggtattgat atttctagcc aggcaaaagc agatgaagca attacaacca ttaatacagc 17941 gctagaaaga gtatctaaag aaagatctat gcttggtgcg gttcaaaata gactagagca 18001 tacgatttct aacttagata atgtatctga aaatctacaa gcttctgagt caagagttag 18061 agacgtagac atggctaaag aaatgatgga attaactaag caaaacattt tacaacaagc 18121 atcaacagct atgttagcgc aagcaaatca ggcaccgcag tcagttcttc aattattagg 18181 ataaataaat atatactaat aacaatcgag ggtcagggga gtatttcc //