LOCUS NC_009515:2 26712 bp DNA linear BCT 24-AUG-2011 DEFINITION Methanobrevibacter smithii ATCC 35061, complete genome. ACCESSION NC_009515 SOURCE Methanobrevibacter smithii ATCC 35061, complete genome. COMMENT locus start: 474285; locus end: 500996 FEATURES Location/Qualifiers source 1..26712 /organism="Methanobrevibacter smithii ATCC 35061, complete genome." gene 0..2600 /gene="" /locus_tag="" /db_xref="474285..476885" CDS 0..2600 /gene="" /locus_tag="" /product="ATP-dependent helicase" /translation="MITEQTKSYSKKQIYKTLHPWVRQWFDETFEDFTPAQKKSIVDI HKGNNILVSSPTGSGKTLTAFLSILSELTTLSQKGELEDKVYCIYISPLKALDNDIEK NLEEPLKGIEKIAGKDLGIRKAVRTGDTTQYQRQKMLKKPPHILITTPETLSILLVAP KFREKLSNVKYVIIDEIHSLAENKRGVHLSLSLERLQHLIGQYTRIGLSATVSPLEEV AKFLVGYEYGVERDCKIININYLKDLDIKVLCPVSDIMLADSEDTRLGTYNLLDDLIQ ENKTTLVFTNTRSGTERFVYNLKKMFPKNYNDENIMAHHSSLSKEVRLATENKLKEGK LKVVVSSTSLELGIDIGYIDLVVLINSPKSVSRALQRIGRSGHKLNEKSTGRIIVTNR DDLVECSVLLKDAKEGKIDKINIPQNCLDVLAQHIYGMSIENPWDIDYAYDVIRKSYC YKNLTRDDYEDVLSYMAGEYEELEERYVYAKIWIDYKENTFGKRGKLARMLYSTNIGT IPDSSGVLVKCDGETVGKIEEDFMERLKKGDTFVLGGQTYRFNYGKGMTINVSPANGP PTIPSWFSQQLPLSFDLAMDIQRFRAHMDAKFRYGKSKQEIMEFIYDYLYVDDFAANS IYEYFVEQYTYAKIPSNQRLLIEYYKGFGDRRFVIFHSLFGRKVNDALSRAVAYIVAR QYNTNVTISISDNGFYLSAEGTLGGLEAFKQLTPENFKNILTQSLNKTETLASRFRHC AGRSLMTLRHYKGEAKSVGRQQVRGKILLKFVQEMDNDFSILKEARREALEDYMDVNN ALKVIELIANGQMEIKTINTIIPTPFAFNLVSQGYLDVLNQNDKAEFTKRMHKAVLEQ IKEKLKESDL" gene 2612..3079 /gene="" /locus_tag="" /db_xref="476897..477364" CDS 2612..3079 /gene="" /locus_tag="" /product="flavodoxin, FldA" /translation="MKTLLVYYSRTQITEKIAKTIQKDLDCDIEEITVGDKYDGTIGY IKGGFDASANRVCEINKVTKNPKDYDLVIIGTPVWAATMATPIYSYLKEYGNQIKNLA SFCTCGGSGYEKTLKKIAKITGKTPIATMYLTKNEIENPEENINNFENKINNR" gene 3085..3453 /gene="" /locus_tag="" /db_xref="477370..477738" CDS 3085..3453 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MTKWGPVFLGFILAVIVKSFFAHYEFIGLLLVGFIVGYLCRDGA ISGMWNAAVAGAFGTIVSAILFVIIATFGGALFGIFGGLVGFTVSGITTVFIVLGYLI YYAIVMGIAGGVGGLISSKK" gene 3466..3873 /gene="" /locus_tag="" /db_xref="477751..478158" CDS 3466..3873 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MDFKNFIDWKSFIMGAAFASFICVVASQYQLDWLYAFAAIGLLY VGYKAKNMKWGAILGAIAATPLFVLAAYGVFGPLSDSSFDPQVSMFVTLIAVLMVGAL VGFVGAYTYRNRQRAIAAKEKQAKTGKNKKGKK" gene complement(3876..4967) /gene="purP" /locus_tag="purP" /db_xref="478161..479252" CDS complement(3876..4967) /gene="purP" /locus_tag="purP" /product="5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase" /translation="MGEVKLEDIFEILDNYDKDNITIATLGSHTSLHILQGAKEEGFR TAIVCEKGREVPYQRFDVADEYIIVDKFKDIVNEDVQQKLRDMNAIVIPHGSFVAYAG LDNVEDKFNVPMFGNRDILRWEAERDKERALLVEGEVRIPYKYDNPSEIDRPVMVKFP GARGGRGYFVASSPEEFNKKIDAMKARGWLEDSDVANAHIEEYVSGCNYCIHYFYSAL EDEVELLGMDTRYESSIDGFVRMPAKDQLDIDLSPSYVVTGNHPAVIRESLLPQVFEM ADKLVESAKKLVAPGLNGPFCMQTLVNDNLEVICFEISARTDGGTNTFMGGSPYSYLT YGKPMSMGRRIALEIKNAIKKEELEKIIT" gene 5165..5704 /gene="" /locus_tag="" /db_xref="479450..479989" CDS 5165..5704 /gene="" /locus_tag="" /product="phosphoesterase, YfcE" /translation="MNFMLIGLISDTHIPDRARELPKNVISSFENVDLILHAGDLTST KVIDELKKIAPTIAIQGNMDRAAGIMLPNAKVIEAEGLKIGIAHGEVYPRADTQQLLY LAKQLDADILVTGHSHQPKIEQIDGVLLLNPGSPVVPRLADRTVMLLEINNKEVDVEV IKIGNPVCSTLDLDKFKGE" gene 5708..6340 /gene="" /locus_tag="" /db_xref="479993..480625" CDS 5708..6340 /gene="" /locus_tag="" /product="cell division protein J (23S rRNA methylase), FtsJ" /translation="MGSRWQMEKKHDPYYKKAKKEDYRSRASYKIKQLDKKFKLIKEG DTVVDLGAAPGGWSQVALEKVGEEGLVIGVDLNRIKPFPEENFHGIRGDFTTTEVQEK VMNLIGGKAKVVISDASPSLCGIKNIDQLRSIDLTNTVIGIADNILEPKGNLVMKVFQ GPEYKDMLTRLKKKYRQVKTTKPPSSRKKSSEMYVVGLDFKPKKNKKSKD" gene complement(6337..6759) /gene="" /locus_tag="" /db_xref="480622..481044" CDS complement(6337..6759) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MRKSRLNLFKSTSMLISVVGIIMIISTIVVVAYVGFSIVSSGIT NEISSGNQYDELAELKSSYSDLESQFDGVKSLYYDNGDTAQVQKYNDARLELTKADSA IQNVQSALDSGKSSNEVDSRIDFAKEKLQNATVAYNNL" gene 6896..8896 /gene="" /locus_tag="" /db_xref="481181..483181" CDS 6896..8896 /gene="" /locus_tag="" /product="ATPase" /translation="MNASTKSRTSVAKFEEFFATTYKDDVFEILEKYPDERSLTVDYN DLEMFDPDLADLLIEKPEEVIEASKSAIKNIDPLVKDADINIRFENLSNIIPLKTLLS KYIGTFVAADGIVRKTDEIRPRIETGVFECRGCMRLHEVEQRSDSRIIEPSLCSECGG RSFRLLQEESKYIDTQTARMQEPLENLSGGTEPKQMLMVLEDDLVDQLNPGDKVRITG TLKTFREERSGKFKNYIYVNHIEPLEQEFEELQLTEEDEAKIIELSKDPDIYEKIIKS TAPSIRGYRDVKEAIALQLFGGAAKELEDETRLRGDIHILIVGDPGIGKSQMLKYVSK LAPRSIYTSGKGTTGAGLTAAAVRDELGGWSLEAGALVLGDQGNVCVDELDKMRSEDR SALHEALEQQTVSIAKAGIMATLNSRCSVLAAANPKFGRFDRFKILAEQIDLPSPILS RFDLIFVVEDKPSVKGDSELAQHILQIHQQNTVNYEIEPELLRKYIAYARKNVNPKLT DEANMVLKEFYVSTRNSSGDEESPVPITARQLEAIIRLAEASAKIRLKDTVDKEDAQK AVRLQLACLKEVGVDPETGEIDIDKVEGRTPKSDRDKLQRIISEIEILEEEYAGQAPM NVLVSNMSDKYDMSEEKVDEMVRNLKHKGVIYEPTNGYLKRA" gene 9002..9409 /gene="" /locus_tag="" /db_xref="483287..483694" CDS 9002..9409 /gene="" /locus_tag="" /product="translation initiation factor IF-2 subunit beta" /translation="MEEYENLLNRAIDQLPPEVFEHKRFKIPKAYSDIQGNRTFIKNF KDVAEDLNRDPQHVLKFLLRELGTAGNLEGSRAILQGKFTHYLINERLEDYVEKYVIC HECNRPDTKIIREDRIFILKCAACGAKAPLKPL" gene 9430..10482 /gene="" /locus_tag="" /db_xref="483715..484767" CDS 9430..10482 /gene="" /locus_tag="" /product="NMD3-related protein (nonsense mediated mRNA decay)" /translation="MIFMFCVECGSTDKKMVGDICIDCFLKDFQMIEIPENIKVEICS HCNSRIEEGKWTDSFLPEDEIIYRALERNIKISNLVENEIINLEIDQIKGTIANCYVE VVGEVYGVQLDETHDTSVRIMKTVCPTCSKLQAGYYESVVQFRANNRDIKAEEYDKAD EVVKRTLNKQSKSDKLAYCPQIAKLKEGYDYYIGSLKSGRKVAESLKEEFGGIIKESP RLISEDKSTGKGLYRIWISIRIPEFEINDFIKHEGKILQVKDIDKNRVVGIDITDHKR HTIPLKESEDITLLKKADEIETTTIISKSPSNIQILDPADYSAVDLDMMDEFKDSNIG DEVKIIKINNYIYLIK" gene 10488..11447 /gene="" /locus_tag="" /db_xref="484773..485732" CDS 10488..11447 /gene="" /locus_tag="" /product="tyrosyl-tRNA synthetase" /translation="MSIEEKIQLIEKGTLEVIDTEELKEVLKKEQPIAYTGYEPSGKI HLGHAVTVQKLKTLQKLGFKIKILLADFHAFLNGKGSIEEIAETAEYNMKCFKALGLD ETTEFILGSSFQLNEDYASKVYKLATLTTLKRARRSMDQVSRHDENPKVASVVYPIMQ TVDMVALDVDVALGGMEQRKIQMLARENLEKIDEKVPVCIHTPLLHGLDGDAKMSSSK GNYIAVDDSVEEITKKIKKSYCPQGETEGNPMIEIAETFVYPNQETLLIKRPEKFGGD IELTHEQLINDFSNGDLHPMDLKNGIKDFLIEHFAPVREYMEE" gene 11451..11660 /gene="" /locus_tag="" /db_xref="485736..485945" CDS 11451..11660 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MDEKQEFEMGLLNGVGEQMLAHTIEKFDVKLEHTEFGPKLIGTY EELEKAKVFLYEAIEARLNQLEGKK" gene 11954..13339 /gene="" /locus_tag="" /db_xref="486239..487624" CDS 11954..13339 /gene="" /locus_tag="" /product="methanol:cobalamin methyltransferase. MtaB" /translation="MKRYTKMEYENPDEMTFGFSKHPVKTKNGLEIGAGYVNPIIKVA PKEGSENSKDTMVSECRNIAISACQRAVNIGLPSFILEQEHIAQQTANPDWAGECTQA QVEVLEKFQDEYGIKTALKATPADIRDEAKGENYRTSSQYQQVMESIEQCCENGASII CIETTGGKSVSDYGISRGDPRAILFGIGVLGSIDMEFMWTKIVKICSKHNVIPGGDTN CSQSNTAMFLAGGLLDKDCSHTLAAIARAIGACNSLVAVECGAKGPLKDCGYENPIVK SISGVPIATEGKNAVCAHSDLMGNLIAGITDCWSNESVYHREEMGGTTPEVWLQATGY EAALMNTAIETENDKILRDLYTLADKYRDPQALILAYDNAHRIGRAIVEYGDDPYQRS IAGALEAGTIIREAVEDKKMQLTRFEQDSLDGAMKIYEKLPEDSGKFIKQSSKRYGRK VEDFDPKNYEL" gene 13358..14185 /gene="" /locus_tag="" /db_xref="487643..488470" CDS 13358..14185 /gene="" /locus_tag="" /product="corrinoid protein (methionine synthase-related), MtaC" /translation="MTYKDLENKINQNKIAIRYNIVVEGAAIKPEEYPEVKEGLPTEE PFKSIALGVLYEDKAKVLSDVKESLENEISPLDIINKGLMKGIDAVSLLYTKGVYFLP DLMLAGDAMMESVKECEKVLGHKSETKGTIVCFVAEGDPHDIGKNLILMFLRAGGYEA IDLGRDVPTEKVVEAVKKYHPLFMTGTALMTTTMTAFPKVVDALEKEGLEVPAIGCGG GAVRKDYVESMPMTVYGVEAYHTPKLADAILKNHKTWEDLRKEYSDIVGEFVPEYSN" gene 14192..15796 /gene="" /locus_tag="" /db_xref="488477..490081" CDS 14192..15796 /gene="" /locus_tag="" /product="methyltransferase activation protein, MapA" /translation="MAEHYAIAIDIGTSGIRAQSYNLTTHKTISTAITLRHPLPGANV VDHLHFALNIGLETAHNILITTINRVIANLNIDLNKVERLAVCGNPIQLSLFNNIEIR DLAFWGENALKEKNITPPSRRGKILNPQAIGLDINPDAKIYIPPAIKHEIGADALAML YKSKALEKDEYSLIIDFGTNAEMALIADGEIYTASAAAGPAIEGQNIEKGRLASPGVI CDINEEEMFWRMKILNDNLIVEDGDLIDPVNGNVIKKSDIQAKGITGTGVIAAFSLGS DDKIIKDGKIKDTIYLQDDVYLKEKDISNIGKALGAFRAGQLTLAESADILLDEIESV YMAGASGFYVDAKKSLNIGQIPPGPQQVYQIGNTSLAMAKDIVLNPELLDELQKLADK IESNHIMLATSEIFEKIYSLELAIYEQGMPFWMYNQWLQKYGIQEIPNIETEPEITKL YPRDISDLGENDLNTVDIENILSAKFDRCIYCMDCVNSCPENALSFEKDEFKLRTDLC SGLGCLRCAGNCKEHAFKYEEFYKDI" gene 15805..16809 /gene="" /locus_tag="" /db_xref="490090..491094" CDS 15805..16809 /gene="" /locus_tag="" /product="methylcobalamin:coenzyme M methyltransferase, MtaA" /translation="MNLKENLENALSGEDVEVKPVISVTQAGIIEAMEQTNASWPEAH TNPEQMAILGSSLHELAGLECARIPFGLTVEAQSMGAEVNLGNNERTPEVTGTPFESA DDIEAPDDFLENGRIPVVLEAIDILKEKYEDLPIIVGITGPFTLTGHLLGIENVVRYM KTDPDEIEIAMENCLDASMDYIESIQKHDADVICVNEPTASPELIDPLQFKSMIKPNL EDLADFIDVQKVLHICGSTQPIISDMSSVGFDGISIEEAVDIPKAKESIEDECVIVGN ISTSKTLLSGTPEDVKEDVKKVLSEDIDIIAPSCGLAPKTPLANVKALVEARNEYFNI" gene complement(16806..17357) /gene="" /locus_tag="" /db_xref="491091..491642" CDS complement(16806..17357) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MSEVLNNVVNVISGLDGVLEVRQLSNDDILKIIDMEAQRSKDIV PVFNEGVQECFKRDVCFVIFKKGYFRVPPTPTVLLTFDGEILGHDVFDPEDKKKFRDD EDIMFLSDDFVIFKDVLNNYNLEKGNEYFVLPPVPFPELDPFKLDGVVSSSPSTKSDE YLKNKYSYGDDSSIATIIVSFNI" gene complement(17362..17940) /gene="" /locus_tag="" /db_xref="491647..492225" CDS complement(17362..17940) /gene="" /locus_tag="" /product="thymidylate kinase, Tmk" /translation="MYIVFEGIDGAGKSTQINLLKDWLDQNGFDVETVVEPTDSEVGK LIRKILQRPDATTDRIQKTLGLLFAADRMLIMDKLNDDSKVILSDRSFISSLAYQEPA EWIEQINKYAKEPDLVLLLDVDVKTSVNRCSKEDEFENEEFLSKVKANYLDLISNFNH EIIDASTGVNKVSTDIKKAVAPYMGICPDCIR" gene 18119..19597 /gene="" /locus_tag="" /db_xref="492404..493882" CDS 18119..19597 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MIQINDKKYILTYLIGFILLATFLFSCNTHNHPKAQIILSILTV IGGIICIRYSIKNKDALHKTAFLIIIIFGLLTVFASPLLVAPDEVEHFARSDLTSEGG LIPNYHENQGYFINNYFHQMTYSQGSTLLDNTSFMHQDITHCKSFFTSVFSQNLFYVY LAQGFGIFIAKMLELPVIFALWLGRLCNLLLYSGIVYFAIKKTPAFKKELLVLSCLPI AVFQAASMSSDGIIFALAILNISYFIQMYKSEIIPNKNIIIYLATGVLIGLIKFPYIF LLLMLFLIPANKFKTKKIAIISKMTALLLIVIAGAYSNFYASKELLKGGRIDYYIQNN VNPTNQINYIIHNPTSAVITFVKSLIFLPYLIFIKDCSFFHLILFPGLDIYNALCLIF FIVFLFLSEDLKMAKRKKLELIILFLIIYTSIFFIQYLSWTPVGYDGILGVGARYFIP ILAILPLVFGHKSNSEKLTKYFIVFTTIFLSGMLLIIIAGFY" gene 19829..22342 /gene="" /locus_tag="" /db_xref="494114..496627" CDS 19829..22342 /gene="" /locus_tag="" /product="collagenase, peptidase family U32" /translation="MVLSELLAPAGSYDVLVIAVNAGADAVYIAGQQYGARAFAKNFT MEEIEKAVEYAHLNGVKVHVTVNTSINNFEIADVMNYLFKLYQIGIDAVIVQDFGICW LLKTLIPDLEVHGSTQMALSNYSSIKWAAKNNIKRVVLPREINVNQIAKTHEQLKKDN INMEIEVFGHGALCYSVSGNCYMSSYNSGRSGNRGACAQPCRREYRLKYRGYNIGNGY LLSTHDLATYNNLDAISDAGVTSLKLEGRMKSGDYIGTIVNSYRNILDGNTGDYAKNL HLVFNRKFTNGYIMGDKPGEVMGRGSSGHEGLYIGDIVKIDGTEVTIEIKNKDNYITL KKGDGIAFKYNGKIKGIYLEDIVKQDENEIVINTTRLVKEGTEVFISFSKSIHENLKK FQKEVIKNNIPLSLTLSWNEDLTGFVNVEYYLDDELINFRHKVIGKFEKAKNKPITKE KIEKQLSKTGGTPFYIDEIKFHNMPDNLFIPISELNQIRREVLSQAQDLLLNHYTPTK KSVKATRKKLNEFYEDYESFNNISKKKNPKISLFIDNLDQLKSISGFDLKRIYFDGNC LYNNPEDYYENIPKLLEEASLMTPDAELVWVLSSFINEKEASKCNEIVKELESKGIII SVMGDFPGMGEIFDCPVYGNHNLNVWNSFTVKNLKEAGFNGLILSSELSGNEIKHLIS KNNTEDIDLELIVNGNLEVIVSKDDFSNLNDGKDFIIHNNADYAILEDKKRKKFKYKV LFDYNKQSHIINKDCLCLIEEMNEIKHLGLDSIILDCRYSNEKYTTNILSIYNDSLKD RDDEELSKYKYQIMDFSQSYINKGNYIEGRLHEDKHENS" gene 22329..24704 /gene="" /locus_tag="" /db_xref="496614..498989" CDS 22329..24704 /gene="" /locus_tag="" /product="collagenase, peptidase family U32" /translation="MRIPELLAPVGSMDHLKVAINAGASSIYLSGKEYGARRFAENFT LNEIAEAVNTAHLHNVKVYVTVNTLIKEDELQDVMNYLSHLYSIGVDAVLVQDLGLVE LINKHLPKLKVHGSTQMTAENQLKLDYLESKGIKRIVLPREMRKDEIKNLKTNMELEI FVHGALCYSYSGQCLMSSFKGGRSGNRGSCAQPCRQKYRLSCLNSEDYYLSPKDLSLY DHLKEIAELNISCIKIEGRMRSKEYLAIAVSNYRKALNKLKSNKISKSEEISLAFNRG FSEGQFNYASSRSIRSGHVGLKLGKVCNSENSQIVIKLDDGLKTIPQKGDGLLLIKAK DDYGFEISQNPLLTTFNHYKKGRNKEIKDINRKDRVLIIKKVKQNKKHHFNLNDSTAY LTKRNRLTSKVKEIENKGSSFIKSKLILTFSIKNKYPHLKGRLTLANKKEIESEVKGE VPFEKPLKRSVDTKTIKKQLLKVDKYPFDIVGVNINYDGTLFIPISEINKIRRELFKK LEKEVYSLYSNKKVKINLENEGNALKTDQYSLSYYTNNLTDLDKINNVKRVYLEIPPE DPSVINQSREEYNINYMVSYLQKAIDISRNRDYELIWKWPDIAHDNLIKVLGKVRGIL NKLHYPIEIMSPDFTGQYGPYSMNVTNTQTIKSLENYKIITLSPELKKEDLKNILDNC SDNSKLEIIVQGSVELMKSRNRLFTKKESKKLKNNTDDIFLIDKKNKRYPIHKSLSNE EIIISNSEDISLLNDITYLKSIGLVNFAIDGRWRDENYLNKIQEYNTAIDK" gene 24759..26711 /gene="" /locus_tag="" /db_xref="499044..500996" CDS 24759..26711 /gene="" /locus_tag="" /product="DNA mismatch repair ATPase, MutS" /translation="MYRKKGLVKMQGEKVTLQNIKGIGDKISEKILNSVGGEENLQKI VENVDVEKIANIDGISQRKAIEIMNQLLNNPTYEFIKSDRAMEIYEDIINKILAYSNT SYSKNRILLLSPSKDIEKIEKQISFVMDAKKQVSQLPIIKLRGLMKNLKEVENPKAEY DASKVILVETEEDNSYLTDLGLNQYYPIITATDSPLLQEELMNYDLIFYVYSQGILDF EGMPNLVMINIEENDYEIVPEKIINFFTHNQDLFNRVYEIQKIRGRETILGEIIPIID ELNVIDKREVDIEELVNSLKKDMDEELENAIQNVDLEGDEILNLLNKNLPPKINKIFD EIINERKKIIREKTGFDFDPYLRKYPIEIDDSEIQRIQLEQSSKKENDIFDVKKSAAI ELNSIKEQAIKEVEEVIKFDYEFSLGSFAYEYDLNAPEFGDEINLKEALHLELALRKD DKNTQTIDYKLTNDENIALLTGANSGGKTTLLETLTQISIMAQMGLPVSAGEAKIKLF DEIYHFSKKRSLDAGAFESFLNVFIPIVTTDSEKLVLLDELEGITELEAAVKIISTFI DMIKESNSYGIIVTHMARELMNYTDIRVDGIEAKGLDENYNLIVDRTPKMNFLAKSTP ELILKRIYEKSDDNLKQVYARILEKF" ORIGIN 1 atgataactg agcaaacaaa aagctattca aaaaaacaaa tatacaaaac cctacatcca 61 tgggttagac aatggttcga tgaaactttc gaagatttta ctccagctca gaaaaagtca 121 attgtagaca ttcacaaagg aaacaatatt ttggtttcat cacctacagg atcaggaaaa 181 acattaactg cttttttatc aatacttagt gaactaacaa ctctttccca gaaaggtgaa 241 cttgaagata aagtttattg catttatatt tcaccactga aagctttgga taatgatatt 301 gaaaaaaatc tggaggaacc tcttaaaggc attgaaaaaa ttgcaggaaa ggatttggga 361 atcagaaagg ccgtccgaac aggtgacact acccaatatc aaagacagaa aatgcttaaa 421 aagcccccac acatcctaat taccacccct gaaactttat ccattttact ggtagcacca 481 aagtttaggg aaaaattaag caatgtgaaa tatgttataa ttgatgaaat acattcactt 541 gctgaaaata aacgtggtgt acatctaagt ttatcacttg agcgtttaca acatttaatt 601 ggacaatata caagaattgg actttcagct actgtcagcc ctcttgaaga agtcgccaaa 661 ttccttgtag gttatgaata cggagttgag cgggattgta aaatcatcaa tataaattac 721 cttaaagacc tggatataaa agttctatgt cctgttagtg acattatgct ggcagatagt 781 gaggataccc gacttggaac atataactta ttggatgacc tgattcagga aaataaaacc 841 acccttgtct ttacaaatac aagaagtgga actgaacgtt ttgtctacaa tcttaaaaaa 901 atgtttccaa aaaactataa tgatgaaaat ataatggccc atcactcttc actttcaaaa 961 gaggttcgtc tagcaactga aaacaaatta aaagaaggaa aacttaaagt cgtagtttca 1021 tcaacatcac tggaattggg aatagatata ggatatattg atttggttgt tcttattaac 1081 tctccaaaat ccgtttcaag agctcttcaa agaatcggaa gaagcggaca caaattaaat 1141 gaaaaatcca ccggaagaat tattgtaaca aatcgtgatg atctggttga atgttctgtt 1201 ttgttaaaag atgccaaaga aggtaaaatt gataaaataa acattcctca aaattgttta 1261 gatgttctgg cccagcacat ttatggaatg agtattgaaa atccctggga catcgattac 1321 gcatatgatg taatcagaaa aagctattgc tacaaaaatt taaccagaga tgattatgaa 1381 gatgttttaa gctatatggc tggagaatat gaagagcttg aagagagata tgtttatgct 1441 aaaatctgga tagattataa ggaaaacacc ttcggcaaac gtggaaaact agccagaatg 1501 ttatattcaa caaatatcgg aacaattccc gacagctcag gagttttagt taaatgtgac 1561 ggtgaaactg tcggaaaaat agaagaggac tttatggaaa gactgaaaaa aggagacact 1621 tttgttttag gcggacagac ataccgtttc aattatggaa aaggaatgac aataaatgtt 1681 tcaccggcta atggccctcc aacaattcct tcctggtttt cacagcaatt accattatct 1741 tttgacttgg ctatggatat tcaaagattc agagcacata tggatgccaa attcagatac 1801 ggcaaaagca aacaggaaat tatggagttc atatacgatt acttatatgt agatgacttt 1861 gcagccaatt caatttatga atactttgta gaacagtaca catatgcaaa aatacctagc 1921 aatcagaggt tattgattga atactataag ggatttggtg acaggcgttt tgtaatattc 1981 cacagcttat ttgggagaaa ggtaaatgat gcactttcaa gagcagtagc ttacattgtt 2041 gcaagacagt acaatacaaa tgttacaata tccatctcag acaacggatt ttacttaagt 2101 gcagaaggaa cccttggagg gctggaagca tttaaacagc taactccaga aaactttaaa 2161 aatatcctaa cacaatcatt aaataaaacc gaaacattag ccagcagatt cagacattgt 2221 gccggcagat cactaatgac ccttagacac tataaaggag aggcaaaatc tgttggtcgc 2281 caacaggtga gaggaaaaat attgcttaaa tttgttcagg aaatggataa tgacttttca 2341 atcctaaaag aagctagaag agaagcattg gaagattata tggatgtcaa taatgctctt 2401 aaagttattg aactaatagc taacgggcaa atggaaatta aaacgataaa tacaattatc 2461 ccaaccccat ttgcatttaa tttagtttca caagggtatt tggatgtatt aaaccagaat 2521 gataaagcgg aatttacaaa aagaatgcac aaagctgttt tagagcagat aaaagaaaaa 2581 ttaaaagaaa gtgatttata aaaagtggta atatgaaaac attattagta tattattcca 2641 gaacacaaat aaccgaaaaa atagctaaaa ccattcaaaa agacctggat tgtgatattg 2701 aagaaatcac agttggagac aaatatgacg gaactatagg atacataaaa ggaggatttg 2761 atgcaagtgc aaacagagtc tgtgaaatta acaaggtaac taaaaatccc aaagattacg 2821 atttagttat aattggaact cctgtctggg cagctacaat ggcaacacca atatacagct 2881 atttaaaaga atatggcaat caaatcaaaa atctggccag tttttgtaca tgcggaggca 2941 gcggatatga aaaaacctta aagaaaatag ctaaaataac cggcaaaact ccaatagcta 3001 caatgtatct gacaaaaaat gaaattgaaa atcctgaaga aaacataaat aactttgaaa 3061 acaaaattaa taacaggtga taaaaatgac taaatgggga ccagtatttc ttggttttat 3121 ccttgcagta attgtaaaat cattctttgc acattatgaa tttataggat tactccttgt 3181 tggatttata gtaggatatt tatgccgtga cggagcaata agcggaatgt ggaatgcagc 3241 agttgccggt gcattcggaa ccatagtatc tgcaatatta tttgttataa ttgctacctt 3301 tggaggagct ctatttggaa tcttcggagg tttagttgga tttacagtat ccggaattac 3361 aacagtcttt atagttttag gatatttaat atactatgca atagtcatgg gtattgctgg 3421 cggtgttgga ggattaattt cttctaaaaa ataaggggaa aaatatatgg attttaaaaa 3481 ttttattgat tggaaatcat ttataatggg agccgcattt gcttcattta tctgtgttgt 3541 tgcatcacag taccaattag attggttata tgcatttgca gctattggtt tactttatgt 3601 tggttataaa gctaaaaata tgaaatgggg agctatttta ggtgcaatag cagcaactcc 3661 attatttgta cttgcagcat atggtgtttt cggacctctt tcagacagtt cttttgatcc 3721 gcaagtaagt atgtttgtta cacttattgc tgttctcatg gttggagcat tagttggttt 3781 tgttggagca tacacttaca gaaataggca aagagcaatt gctgcaaagg aaaaacaagc 3841 aaaaacaggt aaaaataaaa aaggaaaaaa ataattttaa gttattattt tttccaattc 3901 ttctttttta attgcatttt taatttcaag ggcaattctt ctacccatac tcataggttt 3961 tccataagtt aaatagctgt aaggtgaacc tcccataaaa gtattagttc caccatcggt 4021 tctagcactt atttcaaaac agattacttc taaattatca tttactaaag tttgcataca 4081 gaacgggccg tttaatccag gagcaacaag ttttttagca ctttccacta atttatccgc 4141 catttcaaat acttgaggaa gtaaagattc tctgataact gcaggatgat tacctgtaac 4201 cacataagat gggcttaaat caatatctaa ctggtcttta gcaggcattc ttacaaaacc 4261 gtcaatactg gattcatatc ttgtatccat acctaacaat tcaacttcat cttccaaagc 4321 ggaatagaaa taatgtatac agtaattaca tccggaaaca tattcttcaa tatgtgcatt 4381 agctacatct gagtcttcca gccatccgcg agctttcatg gcatctattt ttttattgaa 4441 ttcttcagga gatgatgcta caaaataacc tcttcctccc cttgcaccag ggaatttaac 4501 cataaccgga cggtcaattt ctgaaggatt atcatatttg taaggtattc ttacttcacc 4561 ttcaacaaga agtgctcttt ctttgtctct ttcagcttcc catcttaaaa tatccctatt 4621 accaaacata ggaacattaa atttatcttc aacattgtca agacctgcat atgctacaaa 4681 tgaaccgtga ggtataacaa tagcattcat gtctcttagc ttttgctgaa catcctcatt 4741 gacaatgtct ttaaatttgt caacgattat atattcatct gcaacatcaa aacgttgata 4801 tggtacttct cttccttttt cacaaacaat agctgttcta aaaccttctt cttttgcacc 4861 ttgtagaata tgcaaggaag tgtggcttcc aagagtagct atggttatat tgtctttgtc 4921 gtaattgtct aatatctcaa aaatatcttc aagtttaact tctcccattt taatatctcc 4981 tcaaagaatt gatgtataat aatatatatt taagatatta taaccctttt tgtttttaaa 5041 aaaaagattg aacagaacag ttaattttta aaaaaacaat taacaaaaat tcaatcaaat 5101 gttaaaaaca aatattaaaa aggataactg ataaaataat aaattagaaa tttttaaatc 5161 atgagatgaa ctttatgcta atcggattaa tatcagatac acatattcca gacagagcta 5221 gagaacttcc taaaaatgta atatcctcat ttgaaaatgt tgatttgata ttgcatgcag 5281 gagatttaac ttccacaaaa gtaattgatg aattgaaaaa aatagctcca acaatagcta 5341 ttcagggaaa tatggatagg gcagctggaa taatgttgcc taatgcaaaa gttatcgaag 5401 ctgaaggatt gaaaatcgga attgctcatg gagaagtata tccaagagca gatacacaac 5461 aattacttta tttggcaaaa cagttagacg cagatatttt agttacagga cattcccacc 5521 agccaaaaat agaacagatt gacggagttt tattattgaa tcctggaagt cctgttgttc 5581 caagacttgc agacagaact gtaatgttac ttgaaattaa taataaagag gttgatgtgg 5641 aagttattaa aattggaaat cctgtgtgca gtacattaga tttagacaaa tttaaaggag 5701 aatgaaaaat gggcagtcgt tggcaaatgg aaaaaaaaca tgatccatat tacaaaaaag 5761 ctaaaaaaga agattatcgt tcaagagcat catataaaat caaacagtta gacaaaaaat 5821 tcaaacttat taaagaagga gataccgttg tagatcttgg agcagctcca ggaggatggt 5881 cccaggtagc tttagaaaaa gttggagaag aaggtcttgt aatcggagtg gatttaaaca 5941 gaataaaacc tttccctgaa gaaaatttcc atggaatcag aggagatttt acaactacag 6001 aagttcagga aaaagttatg aatttaattg gaggaaaagc taaagtcgta atttctgatg 6061 cgtcaccatc attatgcgga attaaaaata ttgaccagtt aagatcaatt gatttgacaa 6121 acacagttat tggaattgct gataatattt tagagcctaa aggaaactta gttatgaaag 6181 tatttcaagg tcccgaatat aaagacatgc taaccagact taaaaagaaa tacaggcaag 6241 taaaaacaac aaaacctcca tcatcccgta aaaaaagctc agaaatgtat gttgtgggat 6301 tagactttaa acctaaaaaa aataaaaaaa gtaaagatta aagattattg tatgctacag 6361 tagcattctg taatttttcc ttagcaaaat ctattctact atcaacttcg tttgatgact 6421 tgcctgaatc cagtgcactt tgaacatttt gaatagcgga atcagctttt gttaattcca 6481 atcttgcatc attatatttt tgaacctgag ctgtgtcccc attatcataa tacaaagatt 6541 ttacaccatc aaattgtgat tccaaatcac tatatgaaga ttttagctcc gcaagttcat 6601 catattgatt accagaagaa atttcattag taattcctga tgaaacaata ctaaatccaa 6661 catatgccac aacaacaatt gttgaaataa tcattataat tccaacaaca gaaataagca 6721 tggatgtgga tttaaataaa tttaatctag attttctcat attatcctca ttttattaaa 6781 taaaaaaact atctaataat ttaataatat ttttacttgt ttttagtata taatatttta 6841 cttgccaaat gctcaataca atatttttta aagtatgaaa aattaataat attttaatga 6901 atgctagtac aaaatcacga acatctgttg caaaatttga ggaatttttc gctacaacat 6961 acaaagatga tgtatttgaa atccttgaaa aatatcctga tgaaaggtca cttactgtag 7021 attacaatga tttagaaatg tttgaccctg atttggcaga tttattaatt gaaaaacctg 7081 aagaagttat tgaagcatcc aaaagtgcaa taaaaaatat tgacccttta gtaaaagatg 7141 ctgatatcaa tattcgtttt gaaaatcttt ctaatataat tcctttaaaa accctattaa 7201 gtaagtacat tgggacattt gtcgctgcag atggaattgt aagaaaaaca gatgaaataa 7261 gacctagaat tgaaactggt gtctttgaat gtagaggatg tatgagactg catgaagtag 7321 agcaacgttc cgacagcaga attatagagc cttctttatg tagtgaatgt ggtggaagat 7381 catttagatt gctgcaggag gaatcaaaat acattgatac tcaaacagca agaatgcagg 7441 aaccattgga gaatttatct ggaggaactg aacctaaaca gatgttaatg gttttggaag 7501 atgatttagt agaccaatta aatcccggag ataaagtaag aattacagga actttaaaaa 7561 cattcagaga agagcgcagc ggcaaattca aaaactacat ttatgtaaat catatcgaac 7621 ctttagagca ggaatttgaa gaattgcagc ttacagaaga agacgaggca aaaatcattg 7681 aactttctaa agacccggac atttatgaaa aaatcatcaa atcaactgcc ccatcaatca 7741 gaggttatag agatgtaaaa gaagctattg ctcttcaatt atttggtggt gctgcaaaag 7801 agcttgaaga tgaaactaga ttaagaggag atattcatat tttaatcgtc ggggacccag 7861 gtatcggtaa atcccaaatg cttaaatacg tttcaaaatt agctccaaga agtatttaca 7921 ccagtggtaa aggtacaaca ggagcagggt taactgcagc agcagttaga gatgaattag 7981 gcggatggtc tcttgaagca ggtgcattag tacttgggga ccagggtaat gtatgtgttg 8041 acgaactgga caaaatgagg tcagaagacc gttcagcact tcacgaggca ctggaacaac 8101 aaactgtaag tattgctaaa gcaggaatca tggctacttt aaattcaaga tgttcagttc 8161 tcgcagcagc taaccctaaa ttcggaagat ttgacagatt caaaatactt gcagaacaaa 8221 ttgatttgcc ttccccaatt ttatctcgtt tcgatttaat atttgttgtt gaagataaac 8281 caagtgtaaa aggagattca gaacttgcac agcacattct ccaaatacac cagcaaaata 8341 ctgtaaatta tgaaattgaa cctgaattac tcaggaaata tattgcatat gcccgtaaaa 8401 atgtaaatcc gaaacttact gatgaagcaa acatggtttt aaaagagttt tatgtaagta 8461 caagaaacag ttcaggtgat gaagaatccc cagttccaat tactgcaagg caattagaag 8521 ctatcattcg tttagctgaa gctagtgcta aaataagact aaaagacaca gtagataaag 8581 aagatgcaca aaaagccgtg agactgcaat tagcttgtct taaagaagtc ggtgttgatc 8641 cagaaaccgg agaaatagac attgataaag tagaaggaag aacacctaaa tcagacagag 8701 acaaattgca aagaatcatt tctgaaattg aaatacttga agaagaatat gccggacaag 8761 ctccaatgaa tgttttagta tccaatatga gtgataaata cgacatgagt gaagaaaaag 8821 tagatgaaat ggttagaaac ttaaaacaca aaggagtaat ctacgaacca acaaacggtt 8881 atctcaaaag agcataacct tcttttttta ttttatattt tttaatcaaa taggataact 8941 taataaatga ttaaaatcaa aattaatata ttatatttat actaatttta cggagcgata 9001 atatggaaga atacgaaaat ttattaaata gagcaataga ccaattacct cctgaagtat 9061 ttgaacacaa aagatttaaa attcctaaag cttattcaga tatacaaggt aacagaactt 9121 ttataaaaaa ctttaaagat gttgctgaag atttaaacag agatccacaa catgtattaa 9181 aatttttatt aagagaatta ggtactgcag gtaatttaga aggatcaaga gcaattttac 9241 aaggtaaatt tacacattac ttaatcaacg aaagattaga agattatgtt gaaaaatatg 9301 ttatttgcca tgaatgtaac aggccagata ctaaaattat cagagaagat aggatattca 9361 tattaaaatg tgctgcatgt ggtgctaaag ctccattaaa accattataa tcctatttaa 9421 cttattttta atgattttta tgttttgtgt agaatgtgga agtactgata aaaaaatggt 9481 tggagatatt tgcattgact gctttttaaa agactttcaa atgattgaaa tcccagaaaa 9541 tattaaagta gaaatctgca gccactgtaa cagtagaatc gaagaaggaa aatggacaga 9601 ttcattttta cctgaagatg aaataattta tcgtgcttta gagcgaaaca ttaaaatcag 9661 caatcttgtt gaaaatgaaa ttatcaatct tgaaatcgac caaataaaag gaacaatagc 9721 caattgttat gtggaagttg ttggagaagt ttacggagtt cagcttgatg aaactcatga 9781 cacttcagta agaataatga aaacagtttg tccaacatgc agtaaacttc aggcaggcta 9841 ttacgaatcg gttgttcagt ttagagcaaa caacagagat ataaaagcag aagaatatga 9901 taaagctgat gaagttgtta aaagaacttt aaataagcaa agcaaaagcg acaagcttgc 9961 ttactgccca caaatagcta aactaaaaga aggttacgat tattatattg gatcattaaa 10021 atccggcaga aaagtagctg aaagcttaaa agaagaattt ggaggaatta ttaaagaatc 10081 tccaagactt atcagtgaag acaaatctac tggaaaaggt ctttatagaa tttggatttc 10141 aattagaatt ccggaatttg aaataaatga ttttatcaaa catgagggca aaatactgca 10201 ggtaaaagat attgataaaa atagagttgt tggaatagat atcactgacc ataaaagaca 10261 cacaatacct ttaaaagaaa gtgaagatat aacacttctt aaaaaggctg atgaaattga 10321 aacaacaaca ataatatcaa aatccccaag caacattcaa attttagacc ctgcagatta 10381 ttctgctgtt gatttggata tgatggatga atttaaagat tccaatattg gtgacgaagt 10441 taaaattatt aaaattaaca attacattta tttgattaag tgattaagat gagcattgaa 10501 gaaaaaattc aattaattga aaaaggaaca ttagaagtta tagatactga agaattaaaa 10561 gaagttctta aaaaagaaca acctatagct tacacaggat atgaaccttc aggtaaaatt 10621 catttaggcc atgcagtaac agtacaaaaa cttaaaaccc ttcaaaaatt aggttttaaa 10681 attaaaatac ttcttgcaga tttccatgct tttttaaatg gaaaaggaag cattgaagaa 10741 attgctgaaa ctgcagagta caacatgaaa tgtttcaaag cattaggttt agatgaaact 10801 actgaattca tattaggttc aagtttccaa ttaaacgaag attatgcatc taaagtttat 10861 aaattagcta ccctgactac tttgaaaaga gctagaagaa gtatggatca agtaagccgt 10921 catgatgaaa atccgaaagt ggctagtgta gtttatccaa ttatgcaaac tgtagatatg 10981 gttgctttag atgtagatgt tgctcttgga ggaatggagc aaaggaaaat tcaaatgctc 11041 gcacgtgaaa acttagagaa aattgatgaa aaagttcctg tctgtattca cactccattg 11101 ttacatggtc ttgacggaga tgctaaaatg tcttcaagta aaggaaatta cattgctgtt 11161 gacgattcag ttgaagaaat tactaaaaaa atcaaaaaaa gctattgtcc tcagggagaa 11221 actgaaggaa atccgatgat tgaaatagct gaaacattcg tatatccaaa ccaggaaact 11281 ttacttatta aaaggcctga aaaattcgga ggagacattg aacttacaca tgaacagtta 11341 attaatgatt tctcaaatgg agacttacat ccaatggatt tgaaaaacgg aattaaagat 11401 ttcttaattg aacactttgc tcctgtaaga gaatatatgg aggaataaac aatggatgaa 11461 aaacaggaat ttgaaatggg tttacttaat ggtgtaggag aacagatgct tgctcatact 11521 atcgaaaagt tcgatgtaaa attagaacat actgaattcg gacctaaact tataggaact 11581 tatgaagaac ttgaaaaagc taaagttttc ttatacgaag ctattgaagc cagattaaat 11641 caattagaag gtaaaaaata aaatttacct tttaattaaa atttaattaa aaaaatataa 11701 ataacatttt attttataaa agccaaataa aagcacataa ttaataaaac tctcattttt 11761 caaataaaag aaaaataagc tactaatttt aactattttt aataaacacc tgctctaatt 11821 aaaatatatt aattttaaaa caaataattt catttaattt aaaaacaaat ccaatatatt 11881 aaattaaatt aaaaaatcaa gccaattaat ttatatactt ttaatgatta ttattaacca 11941 tctgaggtga tactatgaaa aggtatacaa aaatggagta cgaaaatcct gatgaaatga 12001 cctttggatt ttcaaaacat cctgttaaaa caaaaaatgg attagaaatc ggagcaggtt 12061 atgttaatcc gataatcaaa gttgctccaa aagaaggaag tgaaaattca aaagacacca 12121 tggtatcaga atgtagaaat attgcaataa gtgcttgtca aagagcagtg aatattggac 12181 tgccttcatt tatcttagaa caggaacata ttgcacaaca aactgcaaat cctgattggg 12241 caggagagtg tactcaggca caagtagaag ttcttgaaaa atttcaagac gaatatggaa 12301 ttaaaactgc acttaaagct actcctgcag atatcagaga tgaagcaaaa ggagaaaatt 12361 atagaacttc ctcccagtat cagcaagtaa tggaaagtat agaacaatgc tgtgaaaatg 12421 gagcatcaat aatctgcatt gaaacaacag gaggaaaatc tgtttcagat tacggaatat 12481 cccgaggaga cccaagagca atattatttg gaattggagt tttaggcagc atagatatgg 12541 aattcatgtg gacaaaaatt gtaaaaatct gcagcaaaca caatgtaatt ccaggaggag 12601 acactaactg ttcacaatca aatactgcaa tgtttctagc aggaggattg ttagataaag 12661 actgttccca tacattagca gcaatagcca gagctattgg agcatgtaac agtttggttg 12721 ctgtagaatg tggtgcaaaa ggacctctta aagactgcgg ttatgaaaac cctattgtaa 12781 aatcaataag tggagttcct attgcaacag aaggtaaaaa tgctgtttgt gcacactctg 12841 atttaatggg aaatttaata gctggaataa ctgactgctg gagtaatgaa tcggtttatc 12901 atagagaaga aatgggtgga acaacacctg aagtctggtt acaggcaaca ggatacgaag 12961 ctgcattaat gaatactgct attgaaaccg aaaatgataa aatattaaga gacctgtata 13021 cattagcaga caaatacaga gaccctcaag cattaattct cgcatatgac aatgcacata 13081 gaattggccg tgctattgta gaatatggtg atgacccata tcaaagaagc atagcaggag 13141 ctcttgaagc tggcaccatt ataagagaag ctgttgaaga caaaaaaatg caattaacca 13201 gattcgaaca ggacagcctt gatggagcta tgaaaatcta tgagaaatta ccagaagatt 13261 ccggcaaatt tatcaaacaa tcatccaaac gatacggacg taaagtagag gactttgatc 13321 ctaaaaatta tgaattataa taaaaagaag ggattaaaat gacttataaa gatttagaaa 13381 ataaaataaa tcaaaataag atagctatta gatacaatat agttgtagaa ggtgcagcta 13441 taaaacctga agaatatcct gaagtaaaag aaggattgcc aacagaagaa ccctttaaat 13501 caatagcttt aggagtgctc tatgaagata aagcaaaagt attaagcgat gttaaagaat 13561 ctcttgaaaa tgagatttca ccattggaca tcataaacaa aggacttatg aaaggtattg 13621 atgcagtgag cttactttat acaaaaggag tttatttctt acctgattta atgcttgcag 13681 gagatgcaat gatggaaagt gtaaaagaat gtgaaaaagt tcttggacac aaaagtgaaa 13741 caaaaggaac tattgtttgt tttgttgctg aaggagatcc acatgacatc ggtaaaaact 13801 taatcttgat gtttttaaga gccggaggat atgaagctat cgatttagga agagatgttc 13861 ctaccgagaa agttgttgaa gctgttaaaa agtatcatcc attatttatg accggtactg 13921 cacttatgac aactacaatg actgcatttc caaaagttgt agatgctctt gaaaaagaag 13981 gtcttgaagt gcctgcaata ggctgtggtg gaggagctgt aagaaaagac tatgttgaaa 14041 gtatgcctat gacagtatac ggcgtagaag cttaccacac accaaaatta gctgatgcaa 14101 tcctgaaaaa ccataaaaca tgggaagatt taagaaaaga gtacagcgac attgtagggg 14161 aattcgtacc ggaatattca aactagataa ccatggcaga acattatgca atagctatag 14221 atattggaac tagcggtatt agagctcaaa gctacaatct aactacccat aaaacaatat 14281 ctacagctat aactttaaga catccattgc ctggagctaa tgtagtagat catcttcact 14341 ttgcattaaa tataggtctc gaaactgcac ataacattct tataactaca ataaacagag 14401 ttatagctaa tttaaatatt gatttaaata aagtagaaag attggcagtt tgcggaaatc 14461 caatacagtt atccttattt aacaatattg aaataagaga tttggctttt tggggagaaa 14521 atgctttaaa agaaaaaaat ataactcctc cgtccagacg tggaaaaata ttaaatcctc 14581 aagcaatcgg cttagatatt aatcctgatg ctaagattta cattcctcca gccattaaac 14641 atgaaattgg agcagatgca ttagctatgc tttacaaatc caaagcttta gaaaaagatg 14701 aatattcact tattatagat tttggaacaa atgctgaaat ggccctgatt gcagacggag 14761 aaatttatac tgcatcggct gctgcaggac ctgctattga agggcaaaat attgaaaaag 14821 gcagactagc ttctccagga gtaatctgcg atattaatga agaggaaatg ttctggagaa 14881 tgaaaattct taatgacaat ttaatagttg aagacggaga tttaattgat cctgttaatg 14941 gaaatgtcat taaaaaatca gacatacaag caaaaggaat taccggaacc ggtgtaatag 15001 ctgcatttag tttaggtagt gatgataaaa tcataaaaga cggcaaaatt aaagatacaa 15061 tttatctgca ggatgatgtt tatctcaaag aaaaagatat ttcaaatatt ggaaaggcat 15121 taggtgcttt tagagccgga cagttaacac tagctgaaag tgcagatatc cttttagatg 15181 aaattgaaag tgtatatatg gccggagctt ccggatttta tgttgatgct aaaaaatcat 15241 taaacatagg acaaattcca ccaggccccc aacaagttta tcaaattgga aatacatcat 15301 tagctatggc taaagatatt gtattaaacc ccgaattatt agatgaattg cagaaattgg 15361 ctgataaaat tgaaagcaat catataatgc ttgctacttc tgaaatattt gaaaaaatat 15421 attccctgga actggctatt tatgaacaag gaatgccatt ttggatgtat aatcaatggc 15481 tgcaaaaata cggcattcag gaaatcccaa atattgaaac agaacctgaa ataactaaat 15541 tatacccaag agatatttca gatttgggag aaaatgattt aaacacagtt gatattgaaa 15601 atatattatc tgcaaaattt gacagatgta tttactgtat ggactgtgtt aattcatgtc 15661 ctgaaaatgc tctgtctttt gagaaagatg aatttaaatt aagaacagac ttatgttcag 15721 gccttggctg tttaaggtgt gctggaaatt gcaaagaaca tgcttttaaa tatgaagaat 15781 tttacaaaga tatatagtga ttaatatgaa tctaaaagaa aatcttgaaa atgcactttc 15841 aggtgaagat gtggaagtta aacctgttat aagtgtaaca caagcaggaa ttatcgaagc 15901 aatggaacag actaatgctt cctggccgga agcacataca aatcctgagc aaatggcaat 15961 tttaggaagt tccctacatg aacttgcagg ccttgaatgt gcaagaatac cttttggact 16021 tacagttgaa gcgcaatcta tgggagctga agtaaatctc ggaaacaatg aacgaactcc 16081 ggaagtaact ggaactcctt ttgaatctgc agatgatatt gaagcaccag atgatttttt 16141 agaaaatgga cgtattccag tagttcttga agctattgat attttaaaag aaaaatatga 16201 agatttgccg ataatcgttg gaattacagg gccatttaca ttaacaggac atttgcttgg 16261 aattgaaaat gtcgtaagat atatgaaaac tgatcctgat gaaatagaaa tagctatgga 16321 aaactgtctt gatgcaagta tggattacat tgaatcaatt cagaaacatg atgcagatgt 16381 tatttgtgta aacgaaccta cagcatcccc agaattaatt gaccctcttc aatttaaatc 16441 aatgattaaa cctaatcttg aagatttggc ggattttatt gatgtgcaaa aagtattgca 16501 tatctgcggg tcaacacaac ctattataag tgacatgtcc tctgttggct ttgacggaat 16561 aagtatagaa gaagccgttg acatcccaaa agccaaggaa agcatcgaag atgaatgtgt 16621 cattgtagga aacatctcaa catccaaaac attattgagc ggaacacctg aagatgtaaa 16681 agaagatgta aaaaaagtat taagtgaaga tattgatatt atagctccaa gttgtggatt 16741 agctccaaaa acaccactag ctaatgttaa agcactagtt gaagctagaa atgaatattt 16801 taatatttaa atattaaatg aaacaataat tgtagctatt gaagaatcat caccataact 16861 atacttattt tttaaatatt cgtcagattt agttgacgga cttgatgaaa caacaccatc 16921 taacttaaaa ggatccaatt ccggaaatgg aacgggaggt aaaacaaaat attcattgcc 16981 tttttccaaa ttgtaattat ttaatacatc tttaaaaatt acaaaatcat cacttaaaaa 17041 catgatatct tcatcatccc taaatttttt cttatcttca ggatcaaaaa catcatgacc 17101 caatatttct ccgtcaaatg tcagtaaaac agtgggagtt gggggaactc tgaaatatcc 17161 ttttttaaaa attacaaaac atacatccct tttgaaacat tcctgaactc cttcattgaa 17221 taccggaact atatcctttg agcgctgtgc ttccatatca attatcttta aaatatcatc 17281 attggaaagt tgccttactt ccaaaacacc atccaaacca cttattacat ttactacatt 17341 gtttaagact tcgctcataa tatcacctaa tacaatcagg acaaataccc atatacggag 17401 ctacagcttt tttaatatct gttgatactt tatttactcc agtacttgca tcaattattt 17461 catgattgaa attgctgatt aaatccaaat aattagcttt gactttactt aaaaattcct 17521 cattttcaaa ttcgtcttct ttagagcatc gatttacaga agttttaaca tccacatcta 17581 aaagtaaaac cagatcaggt tctttagcat atttattaat ctgttcaatc cattctgcag 17641 gttcctgata agctaaacta gaaataaaag agcggtcact taaaataact ttagaatcat 17701 cattaagttt atccataata agcatcctgt ctgctgcaaa tagtagacct aatgtttttt 17761 gaattctgtc agttgttgca tccggtcttt gcagtatttt tctaattaac ttaccgactt 17821 cagaatctgt cggttccaca actgtttcaa catcaaaacc attctgatcc agccaatctt 17881 ttaacaggtt aatctgagta gatttacctg caccatcaat tccctcaaaa acaatgtaca 17941 taattttaaa tttgaattaa actatattaa actttaacta ttttttcaat gtttcattaa 18001 aacaaaaagc aaaacagcta tttaataaat acctatttta catatgaatg acctatgaaa 18061 atccccacaa acatgaacta taaatttatt aagcattatt tataaaaaaa tgatacaata 18121 tgatacaaat aaatgataaa aaatacatac tcacttattt aatcgggttt atattgcttg 18181 caaccttttt attttcatgt aacacccata atcatccaaa agcacagata atattaagta 18241 ttttaactgt aataggtgga ataatttgta taagatattc tataaaaaat aaagatgcat 18301 tacacaaaac agctttttta ataatcatca tatttggatt actaacagta tttgcttcac 18361 cacttcttgt agctcctgat gaagtagaac attttgcaag atctgattta acctcagaag 18421 gaggacttat accaaattac catgaaaatc agggatattt cataaacaac tattttcatc 18481 aaatgacata ttcacaaggt agtaccctac tagacaatac ttcctttatg catcaagata 18541 ttacgcactg caaatcattt tttacatcag tattttctca aaatctattt tacgtctatt 18601 tagctcaagg atttgggata tttattgcaa aaatgttgga attaccagta atattcgcat 18661 tatggttagg tagactttgt aacttattat tatactcagg aattgtatat tttgcaatta 18721 aaaagacgcc tgcttttaaa aaagagttac ttgtattatc atgtcttcca atagctgttt 18781 ttcaagctgc atcaatgagc agtgatggaa ttatttttgc tctggcaata ttaaatattt 18841 cttacttcat acagatgtat aaatcagaaa taatcccaaa taaaaatata atcatttatt 18901 tggcaacagg agtattgatt ggacttatta aatttccata tatcttttta ttactaatgt 18961 tatttttaat acctgcaaac aaatttaaaa caaaaaaaat agctattata tctaaaatga 19021 cagctttact cttaatagtc atagctggag catatagtaa tttttatgct tcaaaagaat 19081 tgttaaaagg tggaagaata gactattaca tccaaaataa tgttaaccca accaatcaaa 19141 taaattatat aattcacaac cctacatccg cagttataac ctttgtaaaa tcattaatct 19201 ttttaccata cttgattttt attaaagatt gttctttttt ccatttaata ctttttccag 19261 ggctagatat atacaatgca ttgtgtttaa tcttctttat tgtattttta ttcttatctg 19321 aagatttaaa aatggctaaa aggaaaaaat tagaattgat aatattattt ttaataattt 19381 atacaagcat attttttatc caatatttaa gttggactcc agtaggttat gatggtattt 19441 taggcgttgg agcccgttac ttcattccaa tattagcaat actgccatta gtatttggac 19501 ataagtctaa cagtgaaaaa ttaacaaaat atttcatagt atttacaaca atattcttat 19561 ctggaatgtt acttataata attgcaggat tttattaaaa gaataagaca tgagcctgtc 19621 tcttcttaaa tttcttattt tttcttttac ttgatttata ttattatttt gaatttaaaa 19681 tacatcatat ccttttaaaa taatatataa aataaaaact aaacagtaaa ctacaacccc 19741 aacaatacat tatcagcgat attttaaaat ttatttatat tacaaaaaac atatttttaa 19801 atgattaaat cttagggtgt aataataaaa tggttttatc agaattatta gctccagctg 19861 gatcttatga tgtgcttgta attgcagtta atgcaggtgc tgatgctgtt tatatagctg 19921 gacaacaata tggagcaaga gcatttgcta aaaacttcac aatggaagag atagaaaaag 19981 ctgtcgaata tgctcattta aatggagtta aagtccatgt tactgtaaat acatcaataa 20041 acaattttga aatagctgat gtaatgaact acctgtttaa attatatcaa ataggaatag 20101 atgcagttat tgttcaggat tttggaatat gctggctttt aaaaactctg attcctgatt 20161 tggaagttca tggatcaaca cagatggcat taagcaatta cagttccata aaatgggctg 20221 ctaaaaacaa tattaaaaga gttgttcttc cacgtgaaat taatgtaaac cagatagcta 20281 aaacacatga acagctaaaa aaagacaata tcaatatgga aattgaagta ttcggacatg 20341 gagctttatg ctatagtgtc tccggaaact gttatatgtc ttcatacaac agcggacgca 20401 gcggaaacag gggcgcatgt gcacagccat gcagacgaga ataccgttta aaatacagag 20461 gatacaatat cgggaacgga tatcttttat caacccatga tctggccaca tacaataatc 20521 tggacgcaat ttcagatgct ggagtaactt cattaaaatt agaaggccgt atgaaatccg 20581 gagactatat aggaaccatc gtaaacagct accgcaatat attggacgga aataccggag 20641 attatgccaa aaatttacat cttgtattca acaggaaatt tacaaacgga tacataatgg 20701 gagataaacc cggtgaagta atgggcagag gcagttcagg ccacgaaggt ttatacatag 20761 gagacattgt aaaaatagat ggaactgaag ttacaattga aatcaaaaat aaagacaatt 20821 acatcacact aaaaaaaggt gacggaatag cttttaaata caacggcaaa atcaaaggaa 20881 tttatttaga agacattgtt aaacaggacg aaaatgaaat tgtaattaat acaacacgtt 20941 tggttaagga aggcacagag gtatttatca gtttttccaa gtcaattcat gaaaatctta 21001 aaaaattcca aaaagaagtc attaaaaaca atatcccact ttcattaacc ctaagctgga 21061 atgaagactt aacaggattt gttaatgttg aatattattt agatgacgaa ttaatcaatt 21121 tcagacataa agtcataggc aaatttgaaa aagctaaaaa caaacctatt acaaaagaaa 21181 aaattgaaaa gcagttatca aaaaccggag gaacaccatt ctacatagat gaaatcaaat 21241 tccacaatat gccggacaat ttatttattc caatcagtga acttaaccag attagaaggg 21301 aagttctatc tcaagcacag gacctgctgt taaatcacta cactccaacc aaaaagtccg 21361 ttaaagctac aaggaaaaaa ttgaatgagt tttatgaaga ttatgaatct ttcaataaca 21421 tcagcaaaaa gaaaaatcct aaaatatcat tatttattga taacttagac cagttaaaat 21481 caatttccgg atttgacctt aaacggattt actttgatgg aaactgttta tacaataacc 21541 ctgaagatta ttatgaaaat attccaaagc ttttagaaga agccagtctt atgactcctg 21601 atgcagaact tgtttgggta ttgtcctcat tcatcaatga aaaagaagca tccaaatgca 21661 atgaaatagt taaagaactt gaatcaaaag gaattattat ttcagttatg ggagatttcc 21721 cgggaatggg tgagattttt gactgtcctg tttatggaaa ccataatctg aatgtttgga 21781 actcatttac agttaaaaat cttaaagaag caggattcaa tggtttaatt ttatcttcag 21841 aactttcagg taatgaaatt aaacatctga tttctaaaaa taacaccgaa gacattgatt 21901 tggaactaat tgtaaacgga aatttagagg ttattgtaag taaggatgat ttcagtaact 21961 taaatgacgg taaagatttc ataatacata acaatgcaga ttatgccatt ttagaagata 22021 aaaaaaggaa aaaattcaag tacaaagtat tatttgacta taataaacaa agccacatta 22081 taaacaaaga ctgcctatgt ttaattgaag aaatgaatga aattaaacac ttaggtcttg 22141 attccataat cctggattgc agatattcca atgaaaagta cacaacaaac atattatcca 22201 tttacaatga ttccctgaaa gacagagatg atgaagagct ttccaaatac aaatatcaga 22261 taatggattt ctcacagtca tatatcaaca agggaaatta tattgaaggc agattacacg 22321 aggacaaaca tgagaattcc tgaattactt gcacctgtag gttccatgga ccaccttaaa 22381 gtagctatta atgcaggagc cagttcaata tatttatctg gaaaagaata tggtgcccgc 22441 aggtttgctg aaaactttac tttaaatgaa atagccgaag cagttaacac tgctcatctg 22501 cacaatgtca aggtttatgt aactgtaaac acattaatta aagaagatga acttcaagat 22561 gtaatgaatt atttgtccca tctatattca ataggtgtag atgcagtttt agttcaggat 22621 ttaggtctgg ttgagctgat aaacaaacac ctgccaaaac taaaagtcca cggttcaaca 22681 cagatgactg cagaaaacca acttaaatta gattatcttg aaagcaaagg aattaaaaga 22741 atagttcttc cccgtgaaat gagaaaagat gaaattaaaa atttgaaaac aaatatggaa 22801 cttgagatat ttgttcatgg agctctgtgc tattcctatt caggacaatg tctaatgagc 22861 agttttaaag gaggtcgaag cggaaacaga ggaagttgtg cacagccctg ccgccaaaaa 22921 tacagattat cctgtttgaa cagtgaagat tattacctct cacctaaaga tttgtcatta 22981 tacgatcatt taaaagaaat tgcagagcta aacatcagct gcatcaaaat agaagggaga 23041 atgagaagca aggaatattt ggctattgca gtgagcaatt ataggaaagc cttaaacaaa 23101 ttgaaaagca ataaaatcag caaaagtgaa gaaataagcc ttgcatttaa tagaggattt 23161 agcgaagggc aatttaacta tgcatcttca agaagtatcc gttcaggaca tgtcggttta 23221 aaattaggta aagtctgcaa tagtgaaaac agccaaatag tcattaaatt agatgacggt 23281 ttaaaaacaa ttccccaaaa aggtgacgga ttattattaa taaaagcaaa agatgactac 23341 ggatttgaaa tttcacaaaa ccctctttta acaacattca accattataa aaaaggcaga 23401 aataaagaaa ttaaagacat taacagaaaa gacagagttt taatcattaa aaaagtaaag 23461 cagaataaaa aacaccattt caatttaaac gattcaacag catatcttac aaaaagaaac 23521 agattaactt caaaagttaa agagattgaa aataagggca gcagttttat caaatccaaa 23581 ttaatactta cattttcaat taaaaacaaa tatcctcact tgaaaggcag gttaactctt 23641 gcaaataaaa aagaaattga aagtgaagtt aaaggagaag ttccctttga aaagcctctt 23701 aaaagaagtg tagatacaaa aacaataaaa aaacagttac tgaaagttga caaataccca 23761 tttgacattg ttggagtcaa tatcaactat gacggaacat tatttatccc aataagtgaa 23821 atcaataaaa tcagaaggga acttttcaaa aaattagaaa aagaagtgta ttccttatac 23881 tccaataaaa aggtaaaaat aaatcttgaa aatgaaggca atgccctaaa aactgaccaa 23941 tacagtttat cctattatac aaataaccta actgatttag ataaaataaa taatgtaaaa 24001 agggtttatt tggagatacc tcctgaagac ccgtcagtaa taaatcaaag cagggaagaa 24061 tacaatataa attatatggt cagctatctg caaaaggcta ttgacatttc cagaaacaga 24121 gactatgaat taatctggaa atggccggac attgctcatg acaatttaat aaaagtttta 24181 ggaaaagtaa gaggcatatt aaacaaactg cactacccta ttgaaataat gtctcccgat 24241 tttacaggcc aatacggacc atactccatg aacgtgacaa atacacaaac aataaagagt 24301 cttgaaaact acaaaataat tacattgtca ccggaactga aaaaagaaga tttaaaaaat 24361 attttagaca attgtagtga caattccaaa ttggaaatta ttgttcaggg atctgttgag 24421 ctaatgaaaa gcagaaacag attatttacc aaaaaagaat ctaaaaagtt aaagaacaac 24481 acagacgaca tcttcctgat tgataagaaa aacaaaagat atcctattca taaaagctta 24541 tctaatgaag aaattataat ttcaaatagc gaagatattt cacttttaaa tgacattacc 24601 tacttaaaat caatagggct tgttaatttt gctattgacg gtcgatggag agatgaaaac 24661 tatttaaata aaatacagga atataacaca gctattgaca aataaaaaat aatacttccc 24721 aaatgctcta gggaattttg gatatatatt taaataaaaa tgtatagaaa aaagggtttg 24781 gttaaaatgc aaggagagaa agtaacattg caaaacataa aaggtattgg agataaaatc 24841 tctgaaaaaa tattaaatag tgttggagga gaagaaaatc ttcaaaaaat agttgaaaat 24901 gtggatgttg aaaaaatagc aaatattgat ggaatcagcc aaaggaaagc tattgaaata 24961 atgaaccagc tattaaataa tcctacatat gagtttatta aaagcgacag ggcaatggag 25021 atttatgaag acatcataaa caaaatatta gcatattcaa acacttcata ttcaaaaaat 25081 aggattttgc tgctttcccc ttcaaaagat attgaaaaaa tagaaaaaca aatcagtttt 25141 gtgatggatg caaaaaaaca ggtttcacag cttccaataa tcaagttaag aggattgatg 25201 aaaaacttaa aggaagttga aaatccgaaa gccgaatatg atgcaagtaa agttatttta 25261 gtggaaacag aagaagataa ttcatatctt actgatttag gtctgaatca gtattatcca 25321 ataattacag ccactgattc cccgttactg caggaggaat taatgaatta tgaccttatc 25381 ttttatgtat attcacaggg aatacttgat tttgaaggaa tgccaaacct tgtaatgatt 25441 aatattgaag aaaatgatta tgaaatagtt cctgaaaaaa taataaactt ctttacacat 25501 aaccaggatc tttttaacag agtttatgaa atacaaaaaa tcagaggccg ggaaacaatt 25561 ttgggagaaa ttatcccaat tattgatgaa cttaatgtta ttgataaaag agaagtagac 25621 attgaagaat tagtcaattc tttaaaaaag gatatggatg aagaactaga aaatgccata 25681 caaaatgttg atcttgaagg agatgaaatt ctcaacctat taaacaagaa tctccctcca 25741 aagattaata aaatatttga tgaaattata aatgaaagga agaaaatcat cagagaaaaa 25801 acaggatttg attttgatcc gtatctcaga aaatatccta ttgaaattga cgacagcgaa 25861 atccaaagaa tccaactgga acagtcatcc aaaaaagaaa atgatatttt tgatgttaaa 25921 aaaagtgctg ccattgaatt gaactccata aaagaacagg caatcaaaga agttgaagaa 25981 gtaattaaat ttgactatga atttagctta ggcagctttg catatgaata tgatttaaat 26041 gcacctgaat ttggcgatga aataaattta aaagaggcac tgcatctgga actggccctt 26101 agaaaagatg ataaaaacac acagacaatt gattacaaac ttacaaatga cgaaaacata 26161 gccctgctta ccggggcaaa cagcggaggt aaaacaaccc ttcttgaaac actaacccaa 26221 atttccataa tggcgcaaat ggggcttcct gtaagtgccg gtgaagccaa aatcaaattg 26281 tttgatgaaa tatatcattt ttcaaagaaa agatcactgg atgccggagc ttttgaatct 26341 tttttaaatg tatttattcc aattgtaaca acagacagcg aaaaattagt attgcttgac 26401 gaacttgaag gaataacaga actggaagct gcagttaaaa ttatttcaac atttatagat 26461 atgattaaag aatccaattc ctacggaata attgtaacac atatggccag ggaactgatg 26521 aattacacag atattcgtgt agacggtatt gaagcaaaag gattagatga aaattataat 26581 ctgatagtgg acagaactcc gaaaatgaat ttccttgcaa aaagtactcc tgaacttatc 26641 ttaaaaagga tttatgaaaa atcagacgat aatctaaaac aggtatatgc aagaatcctg 26701 gagaaatttt aa //