LOCUS NC_009457:3 17600 bp DNA linear BCT 10-SEP-2013 DEFINITION Vibrio cholerae O395 chromosome 2, complete sequence. ACCESSION NC_009457 SOURCE Vibrio cholerae O395 chromosome 2, complete sequence. COMMENT locus start: 1068000; locus end: 1085599 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.535300; n0_4mer:D = 31.597367; n0_4mer:PS = 44.094960 FEATURES Location/Qualifiers source 1..17600 /organism="Vibrio cholerae O395 chromosome 2, complete sequence." gene 102..620 /gene="hcp-2" /locus_tag="hcp-2" /db_xref="1068101..1068619" CDS 102..620 /gene="hcp-2" /product="hcp protein" /translation="MPTPCYISIEGQTQGLITAGACTADSIGDSFVEGHEDEMLVQQF DHVVTVPTDPQSGQPSGQRVHKPFKFTVALNKAVPLLYNALSSGEKLKSVELKWYRTS IEGKQENFFTTKLENASIVDIHCEMPHCQDPAKSDFTQNVTVSLSYRKITWDHVNAGT SGSDDWRKPIEA" gene 748..4035 /gene="vgrG-1" /locus_tag="vgrG-1" /db_xref="1068747..1072034" CDS 748..4035 /gene="vgrG-1" /product="vgrG protein" /translation="MATLAYSIEVEGLEDETLVVRGFHGQESLSNSVFLGQACYGFRY EVQLASRVSNLTAEQMVDKRAELKLYRNSQLVQRVHGIVRAFSQGDIGHHHTFYQLTL VPALERLSLRHNSRIFQKQTVPEILSILLQEMGINDYAFALKRDGVQREFCVQYRESD IDFLHRLAAEEGLVYSFVHEAGKHTLYFSDASDSLSKLPEPIPYNALVGGAIDTPYIH GLTYRTQAEVSEVQLKDYSFKKPAYSFLQTVQGTELDYQQTRYQHFDAPGRYKDDVNG AAFSQIRLDYLRRHAHTATGQSNEPLLRAGYKFDLQEHLDPAMNRDWVVVSINHQGEQ PQALQEDGGSGATTYSNQFSLIPGHLHWRAEPQPKPQVDGPMIATVVGPEGEEIFCDE HGRVKIHFPWDRYSNGNEQSSCWVRVSQGWAGSQYGFIAIPRIGHEVIVEFLNGDPDQ PIITGRTYHATNTPPYTLPEHKTKTVLRTETHQGEGFNELSFEDQAGKEQIYLHAQKD FDGLIENDQFTQIKHNQHLTVEWESREAVTGEQVLSIEGSLHVKTGKVRVNEAGTEIH VKAGQKVVIEAGSEITVKAGGSFVKVDPAGVHLSGALVNLNSGGSAGSGSGFGGAMPA LPGGLEPAVALAPPQTISYQALLQAEQANVPAVKVCPLAAQEATPAVNSITPPPPPPI APPMAPPQPIMNPQPTANAQPNLGRSTKATPDFPTHFPKSSIGIENELAGLVVAMPAN SAQKFGYVKSAQGDALFMLTKDMNQGSYQRPPSLQDGKNYQNWQTHTVELVSYPCEMD DKAAVETRKQAMLWLATHFTTHIDQSNHQPLAPIQSEDGRFVIEITNAKHVIAAGNGI SAESQGQTITMTPSGQQATVGVAAKGFGTSATPELRLLESAPWYQKSLKSQFASLTSA ENLDDKELAANVFAYLTSIYLKTAELAKKFGIYINEWDPMSEQITPNANGLTDPKVKN AWEILPRTKPSKIVEILSKSDAKAVMKHIKPQLQSRYSESLSKNVFQYFQDGGEVAGH GINNATVGDKHSPELAILFEFRTVPNELQSYLPKTESTTKSEVKLLDQFDPMKRKTVI QQVESLV" gene 4170..5030 /gene="" /locus_tag="" /db_xref="1072169..1073029" CDS 4170..5030 /gene="" /product="hypothetical protein" /translation="MATHYCLVENGMEKMLLQWLSEQTSNVYWLADHLTFKQAVANNS GIVFDGTQVVFHGETFAPVMALSPWLVPVSDMVSDIDYECLQQGIFLSCSCPSTELLS HLQSLLIAALEGEEVLFRFYDRQVIVPMLERMDEIEKNQFLGKINQLVVFDSHEKNRL VSFTNTSDAQFTAKKTTWWVIKRHHLEAHENLPLVQANLESWLWRHFPKVMNEYLIQG RDIASMLAPSLSVPEQTLTYRVLSAAIVAVVGAEQLTQPSMIEFLRDYNNEEAQLALH ALTRQFELRG" gene 5033..6958 /gene="" /locus_tag="" /db_xref="1073032..1074957" CDS 5033..6958 /gene="" /product="hypothetical protein" /translation="MDSFNYCVQCNPEENWLELEFRSENDEPIDGLLVTITNQSAPSN TYTQTTSSGKVLFGKIAAGEWRASVSQASLLTEVEKYASRKEGQESPVKKRAAAELDA ADKDTKQYRFTTIGDFWDEAPKDEFLQKQHKGIDVNASAEKAGFRLSHNQTYVFEIKA LRSYMPVIIDTDEFNLVNSYTFALLSKLAYATNDFNRDDGKTIDNQGAISTVISQLKR KERPTYSGDLQAKWLLEEIPYSKALSAQYYAEDDVGSEGYIIFNDELAIIGVRGTEPY FQSKKPPVDNTKFKIIKAASGMAAVIADKIESATDSPGMKDLIITDLDAAQIAPEEFG GTYVHRGFYQYTMALLSLMEKDLGLHKIKKFYCCGHSLGGAGALLISALIKDSYHPPV LRLYTYGMPRVGTRSFVERYQNILHYRHVNNHDLVPQIPTVWMNTDVSEGFHVLDVFK SRVDLMRKMLTDDDDDNYQHHGHLSQLLTYNSNNQVLLTPKQTQVTMLDLANLATNDS VAMVDGLSDASIVEHGMEQHIPNLFEQLTALSDESLMVHYQRAISALEQEIATLQQSY LTVKQAWIESIGNGTPTMNIGRLMSEMHSINKLIENRNKIRGELRQIVSDPQRMPATK FLISQQTLPDEIKVQIR" gene 6955..7698 /gene="" /locus_tag="" /db_xref="1074954..1075697" CDS 6955..7698 /gene="" /product="hypothetical protein" /translation="MKLLNNLAIKKLISVVVLFIALFFLGYDYYQTSQPNIWGDEPDE SYITISGKKPIDAYLEVWTHFWVTGDECEAYSYDLFGQKAHQGGKISQKITHDFAKDG SNFEFRIPYQTYKNSQNCIVELRDFSIQAHNDFDTVGFAQLRFSPAGREYYNREVDLN SLFTADNCNSDIFKSIRKEWAGAIGCHFYVDGKKKTKDEEFNAYTIYYDFSKFNNDTV IHYDILAGENYRSEPLSSAQKTAVVSDDN" gene 7843..8580 /gene="" /locus_tag="" /db_xref="1075842..1076579" CDS 7843..8580 /gene="" /product="hypothetical protein" /translation="MKKLIFLLSALLLNSCSTNPVYETEQPWTWRVGVTMPSFYPVNV TRVYGVNNKEDWTVLIHNFMTFVSDSDISYIHQIFPDYDGFGLPHALGITSRSQIGVG TTQLPDTLYMYWVSLFDTKFYVTKYEIPDNVKQLVATKKTYTKWNGFIVDPCYRTEFI FGLLPNGQAKVWLSGCGETIYLTELAPDQILDRDSNGVKFDSYRKSSSFVDVQQRAKD AGVELEPIPWDKVNKVYSRYEIKTLGE" gene 8668..9306 /gene="" /locus_tag="" /db_xref="1076667..1077305" CDS 8668..9306 /gene="" /product="hypothetical protein" /translation="MVIQNFEAFLIAITILTLTPGLDTALVIRNTSRAGFADGCTTSL GICFGLFVHATFSAIGISAILAQSAELFQIVKMVGAAYLIWLGISSLRSLMKTGQGIE VASLAHAQFRLTRSLREGFLSNVLNPKTAVFYLAFLPQFINPDYSPLAQSLLMALIHF AIAMVWQCGLAGALSSAKNLLKNASFMRWMEGTTGVVLVALGIKLLLEKPQA" gene complement(9379..10749) /gene="" /locus_tag="" /db_xref="1077378..1078748" CDS complement(9379..10749) /gene="" /product="sodium/alanine symporter" /translation="MNNLQSFLQTVDSLVWGPPLLILLVGTGVYFTFRLGLLQFRRLP TALAMVFGREKSSDKQGDVSSFAALCTTLSATIGTGNIVGVATAIKLGGPGALFWMWL AALFGMATKYAECLLAVKYRQVDDKGQMVGGPMYYLRDGVGSKTLAVLFAVFAVGVAC FGIGTFPQVNAILDATQISFGVPREASAVVLTVLVAIVTIGGIQSIAKVAGKVVPAMA LFYIVACLSVIVTNADKLADAVELVLVSAFTSTAATGGFLGASIMLAIQSGIARGVFS NESGLGSAPMAAAKTDSCVEQGLISMTGTFFDTIIICTMTGLALILTGAWQSDLSGAA MTTYAFATGLNAQTIGPMLVSIGLMFFAFTTILGWNYYGERCMVFLFGTKAVLPYKIV FIGLIASGAFLHLDLIWIIADIVNGLMAIPNLIGLAALRHVVVEETKQYFAARYQYSE AEAQVQ" gene 11252..11410 /gene="" /locus_tag="" /db_xref="1079251..1079409" CDS 11252..11410 /gene="" /product="hypothetical protein" /translation="MVRLIAIALLIALAFVLIRYRTNEKLQKGVVIVILATFVTYTAF LMISELIR" gene 11427..12161 /gene="" /locus_tag="" /db_xref="1079426..1080160" CDS 11427..12161 /gene="" /product="hypothetical protein" /translation="VNKHNEFDDNEEVVVIERRDKQSYLYIAIAAVLGIALGGLIGSS VTTSRWETSYQTLQNQLEQLNNAKAEVSKAAELSEQNQEEAWQHKMDEALEKQREEWQ AEAVQRDKYVAELEKQNLNLEQQLNEQKMALELANTQNNQLNRQADMQVTMLERSREL FQRELKIKQELEGLQKERDSLVPKLKVLKKECDIYLEGKSWDAKSDACDKQDEANSRV SQIDQMIRVHQMDLEEIKALSEEIGL" gene complement(12310..13347) /gene="potD-1" /locus_tag="potD-1" /db_xref="1080309..1081346" CDS complement(12310..13347) /gene="potD-1" /product="spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein" /translation="MKNKLFASALCAAALFTTNAMAKDQELYFYNWSEYIPSEVLEDF TKETGIKVIYSTYESNESMYAKLKTQGAGYDLVVPSTYFVSKMRKEGMLQEIDHSKLS HFKDLDPNYLNKPFDPGNKFSIPYIWGATGIGINTDMLDKKSLKNWGDLWDAKWAGQL MLMDDAREVFHIALSKLGYSPNTTNPKEIKAAYRELKKLMPNVLVFNSDFPANPYLAG EVSLGMLWNGSAYMARQEGAPIQIIWPEKGTIFWMDSISIPAGAKNIEAAHKMIDFLL RPENAAKIALEIGYPTPVKTAHDLLPKEFANDPSIYPPQSVIDNGEWQDEVGEASVLY DEYFQKLKVND" gene complement(13458..14558) /gene="potD-2" /locus_tag="potD-2" /db_xref="1081457..1082557" CDS complement(13458..14558) /gene="potD-2" /product="spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein" /translation="MTEVILFFFATPKRATFSLELTSMKKLATLLAGSACALSLLSGT AAAEDKELVFMNWGPYINSGILEQFTKETGIKVIYSTYESNETLYAKLKTHNQGYDLV VPSTYFVAKMRDEGMLQKIDKSKLSNFKNLDSNYLDKPYDPNNDYSIPHVVAITGLAV NTDMYDPNDFQSWGDLWKPELKGQLMLMDDTREVFHIALRKLGYSGNSTGDKQIDEAY AELQKLMPNVLVFNSDNPAAPYLSGEVGLGMLWNGSAAAAQKEGLPIKLVFPKEGGIG WVDNFAISSGAKNVDAAHKMIDFLLRPEIAEQISRDTGYLTGVKASNDKFQDVAPLFP SQEDLDRVEWQSAVGDKTVKYEEYFMKLKAGQ" gene complement(14592..15362) /gene="potC" /locus_tag="potC" /db_xref="1082591..1083361" CDS complement(14592..15362) /gene="potC" /product="spermidine/putrescine ABC transporter membrane protein" /translation="MGRSIRFSFMSLVYLFLYLPIIVLIANSFNENKFGIKWGGFTTK WYHALMNNDSLMQAAWHSINVAVFSATAATLIGSLTAVALFRYQFKGKKVVSGMLFVV MMSPDIVMAISLLALFLVMGAKLGFFTLLIAHITFCLPFVVVTVYTRLNGFDVKMLEA AKDLGAGEWVILKKIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIY SMVKVGISPEVNALATVMLVVSLVLVVASQLLAREKVK" gene complement(15362..16222) /gene="potB" /locus_tag="potB" /db_xref="1083361..1084221" CDS complement(15362..16222) /gene="potB" /product="spermidine/putrescine ABC transporter membrane protein" /translation="MMSKKLNLQNAIVTLIVGWLVLFVLIPNLMIIGTSFLTRDEANL IKFAFTFENYTRLLDPLYGKVMLHSFYMAIVATLICLVIGYPFAYIVAKMPEKWRPFM LFLIIVPFWTNSLIRTYGLKIVLGTQGILNQALMSLGLIDAPLRIMFTETAVMIGLVY ILLPFMILPLYSAIEKLDGTYIEAARDLGANKFQTLVRVILPLTMPGIIGGCLLVLLP ALGMFYIADLLGGAKNLLIGNVIKSQVLNARDWPFGAATSIALTLAMAIMLYAYYRAG KLLNKKVELD" gene complement(16203..17336) /gene="potA" /locus_tag="potA" /db_xref="1084202..1085335" CDS complement(16203..17336) /gene="potA" /product="putrescine/spermidine ABC transporter ATPase" /translation="VGEIQTLNEQHSVGKPVIRLSGISKSFDGKEIIGNLNLDVNHGE FLTILGPSGCGKTTVLRMIAGFETADQGQILLDDQDVTQVPAEQRHVNTVFQSYALFP HMTVFENVAFGLRMQKVPQSEIEPRVMEALRMVRLAEMAQRKPHQLSGGQQQRIAIAR AVVNKPKVLLLDESLSALDYKLRKQMQSELKQLQRQLGITFIFVTHDQEEALSMSDRI IVMRLGKIEQDGSPREIYEDPKNLFVARFIGEINVFQATTIDRIDEKRIRVDIEGIES IVYYEDEVKAGDKLQVLLRPEDLRIEEIKESEEKGIVGHVTDRTYKGMTLESVVELES GMCVMVSEFFNEDDPDVDHSIGQKVAVTWVESWEVVLNDEQKA" ORIGIN 1 tgtgaaagtt ggcatcccac ttgctctttg tatcgcgacg gtgcgcagag cgcgttaact 61 cattcattga cttaaaaatg atttattgaa aggaaatagc catgccaact ccatgttata 121 tctctatcga aggccaaact cagggtctta tcactgcagg tgcatgtact gctgactcta 181 tcggcgattc attcgttgaa ggccacgaag atgagatgct ggttcagcag tttgaccacg 241 ttgtgactgt accgactgac ccacaatctg gtcagccttc aggccaacgt gtgcacaagc 301 cattcaaatt cactgtggcg ctgaacaaag cggttcctct gctgtacaac gcgctctctt 361 ctggtgagaa gctgaagtcg gttgagctga agtggtaccg tacctctatc gaaggtaaac 421 aagagaactt cttcaccact aagctggaaa acgcgtctat cgtcgacatc cactgtgaaa 481 tgccacactg ccaagaccca gcaaaatctg actttactca gaatgtgact gtgtctctgt 541 cttaccgcaa aatcacttgg gaccacgtta acgcgggcac ctcaggctct gatgactggc 601 gtaagccaat cgaagcgtaa tttacgctgc gagaatgtcg ctcaccttcg ggtgggcggc 661 tgtgaacctt aaacccagag tatcgtttgg cgcggtattg tgggtttaag gttttgccat 721 ttttaatgta ggggaaggaa aggcaggatg gcgacattag cgtacagcat tgaggtggaa 781 gggctggaag atgagactct ggtggtcaga ggcttccacg ggcaggagtc actctctaat 841 agtgtttttt tagggcaagc ctgttacggg tttcgctacg aagtgcaact ggcgagtcgg 901 gtatcaaacc tcaccgccga gcagatggtg gataagcgtg ccgagctcaa gctttaccgc 961 aactcacagt tggtgcagcg cgtgcacggc attgtgcgtg ctttcagcca aggcgatatc 1021 ggccatcacc acaccttcta ccaactcact ttagtccctg ccttagagcg cttatccctg 1081 cgtcataaca gccgcatttt ccaaaagcag actgtccctg agattctctc tatcttgctg 1141 caagagatgg gcatcaacga ttacgctttt gcgctcaaac gtgatggcgt gcagcgtgag 1201 ttttgtgtgc agtaccgcga aagcgatatc gactttctgc accgcctcgc cgctgaagaa 1261 ggtttggtgt acagctttgt ccatgaagcg ggcaaacata ccctctattt cagtgatgcc 1321 agtgatagcc taagcaaact gccggagcct atcccataca acgctttagt cggtggcgcg 1381 atagataccc cgtatatcca cggcttaacc tatcgcaccc aagcagaagt gagcgaagtt 1441 cagctcaaag actacagctt caaaaagcca gcctactcct ttttgcaaac cgtgcagggt 1501 actgagctgg attatcagca aacgcgctac caacattttg atgcgccggg gcgctacaaa 1561 gacgatgtga acggcgccgc ctttagccaa atccgtttag actacctgcg ccgccatgcc 1621 cataccgcaa cagggcagag caacgagccg ctgctgcgtg ccggctataa gtttgacctg 1681 caagagcacc ttgaccccgc gatgaaccgc gattgggtgg tagtgtcgat taaccaccaa 1741 ggtgagcagc cgcaagcgct acaagaagac ggtggcagcg gcgctactac ttacagcaat 1801 cagttcagct taattccggg gcatcttcac tggcgcgccg agccacaacc caaaccgcaa 1861 gtcgatggtc caatgattgc cacggtcgtc ggtcctgaag gcgaagaaat cttctgtgat 1921 gaacatgggc gggtgaaaat ccatttcccg tgggaccgtt actcgaacgg taacgagcaa 1981 agctcctgtt gggtacgggt gtcgcaaggt tgggcgggca gtcagtatgg ctttatcgct 2041 attccgcgca tcggccatga agtgattgta gagtttttaa acggtgaccc agaccaaccg 2101 attatcactg gccgcactta tcatgcgacc aacacgccgc catacacctt gcctgagcac 2161 aaaaccaaaa ccgtgctgcg caccgagacg caccaagggg agggctttaa cgagctcagt 2221 tttgaagacc aagcgggcaa agagcaaatc tacctgcatg cgcagaaaga ttttgatggt 2281 ttgattgaaa acgaccaatt tacccagatt aagcacaacc aacacctgac ggtggagtgg 2341 gaaagtcgag aagcggtaac gggcgagcaa gtgctgagta ttgaaggctc gctgcatgtg 2401 aaaacaggca aagttcgggt caatgaagcg ggtacagaga tccatgtaaa agcgggacag 2461 aaagtggtga ttgaagcggg ctccgagatt accgttaaag cgggcggcag ctttgtgaaa 2521 gtcgatccgg ctggggtgca tctgtccggt gctttggtca atctcaactc tggcggcagc 2581 gctggtagtg gtagcggctt tggcggtgca atgcccgcct taccgggcgg cttagaaccc 2641 gccgtggcac tggctccacc gcaaaccatc tcttaccaag cgttgctaca ggccgagcaa 2701 gcgaatgttc ctgcggtgaa ggtgtgtcct ttagccgctc aagaagcaac gcctgcggtg 2761 aatagtatca cgccgcctcc accaccaccg attgctccgc caatggcccc accacaacca 2821 ataatgaatc cacagccaac cgctaacgcg cagcctaatc ttggaagatc cactaaggca 2881 acgccggatt ttccaacaca tttcccgaag tcatccattg gcattgagaa tgagttagct 2941 ggtctagtgg tggctatgcc agccaactcg gcacagaaat ttggctacgt gaaaagtgca 3001 caaggtgatg cgctgtttat gttaacgaaa gacatgaacc aaggttcgta tcagcggcca 3061 ccttcattac aagatggaaa aaattatcag aattggcaga cgcatacagt agagttggtg 3121 agctaccctt gtgaaatgga cgataaagct gccgttgaaa cacgcaaaca agccatgttg 3181 tggttagcaa cccactttac tacgcatatc gaccagtcca atcatcaacc attagctcct 3241 attcaaagtg aagacggacg ctttgttatc gaaatcacta atgcgaagca tgtgattgct 3301 gcgggcaatg ggatttctgc agaatctcaa ggtcaaacaa tcacgatgac accaagtgga 3361 caacaagcca cagtgggtgt tgctgctaaa ggtttcggga cgagtgcaac gccagaatta 3421 aggttacttg aatcggcacc ttggtatcag aaatcactca agagccaatt tgcatctcta 3481 acgagcgcag aaaacttgga tgataaagag ttagctgcaa acgtatttgc ttatctgacg 3541 tctatttatt taaaaacagc agagctagcg aagaagtttg gtatttacat caatgaatgg 3601 gaccccatgt cggagcaaat tactccaaat gcgaatggat taacggatcc aaaagtaaaa 3661 aatgcatggg aaatattgcc acgtacaaaa ccaagcaaaa tagtagaaat actcagtaag 3721 agtgatgcca aagcggttat gaaacatatc aagcctcaat tgcagtctcg ctattctgag 3781 agtttgtcga aaaatgtatt tcaatatttc caagatggtg gtgaagtagc cggacacggt 3841 attaataatg cgacggtcgg tgataaacat agtccggaat tggcgatttt gtttgagttc 3901 agaactgttc cgaatgaact gcaaagttat ttgcctaaaa cagaatcgac aactaagtca 3961 gaagtgaagt tactcgatca gtttgatcct atgaagcgta aaacagtaat tcaacaagta 4021 gaatcgcttg tgtaaaatag tggcgatgca tttgataaat ggtaccaaag ctaccgagac 4081 tccatgaatc aacctcccgt taaaaatgcg aagaaaattg cttccgcgaa tcaaaaagca 4141 caatgggtta aagagcataa tcctcaagaa tggcaacgca ttattgctta gtggaaaatg 4201 gaatggaaaa gatgctttta caatggttga gtgaacagac atcaaacgtc tattggcttg 4261 ctgatcattt aacgtttaaa caggcggtgg cgaataacag tggaattgta tttgatggta 4321 cacaagttgt tttccacgga gagacctttg cccctgtgat ggcgttatcg ccctggttag 4381 tccctgtctc tgatatggta tcggatatcg actacgagtg cttacaacaa ggtatattcc 4441 taagttgctc ctgtccctcc acagagttat taagccatct ccaaagcctt ttgattgcag 4501 cactggaagg cgaagaagta ctgtttcgtt tttatgatag gcaggtcatt gtgcctatgc 4561 ttgaacgaat ggatgaaata gaaaaaaatc agttcttagg taagataaat cagttagtcg 4621 tgttcgatag ccatgagaaa aatcggttag tctcatttac caatacatca gacgctcagt 4681 ttacggccaa aaagacaacg tggtgggtga tcaaacgaca ccatttggag gctcatgaga 4741 atttgcctct tgttcaagct aacctcgaat cttggctatg gcggcatttt ccaaaagtga 4801 tgaacgagta cttaattcaa gggcgtgata tcgcttccat gctcgctcca tctctctctg 4861 ttcctgaaca aaccttaaca tatcgtgtgt taagtgccgc tatcgttgct gttgtcggtg 4921 ccgaacaatt gactcagcct agcatgattg aatttctacg agactataac aacgaagaag 4981 ctcagctcgc tctgcatgct ttaactcgtc aatttgaact aaggggataa ccatggattc 5041 atttaattat tgcgtgcagt gtaaccctga ggaaaactgg ttagagctag agtttcggag 5101 tgaaaatgat gaaccgatag atggtttgct agttacgatt acgaaccaaa gtgccccctc 5161 taacacatac acgcaaacca caagttcggg taaggtgttg tttggcaaga ttgcggctgg 5221 ggaatggcgt gcttctgtaa gccaagcttc tctgttaact gaagtcgaaa aatatgccag 5281 ccgtaaagag ggacaagagt cgccagtgaa aaaacgagct gcggcagaac ttgacgccgc 5341 agataaagat acgaagcagt accgctttac cactattggt gatttctggg atgaagcacc 5401 aaaagatgag tttttacaaa agcagcataa agggatagat gtcaatgctt ctgctgagaa 5461 agcagggttt agactcagtc ataaccagac ctatgttttt gaaatcaaag cactacgtag 5521 ctatatgcca gtgattattg ataccgatga atttaacttg gtgaatagtt atacctttgc 5581 gttgttgtcg aaattagctt atgcgactaa cgattttaat agggatgatg gtaagacaat 5641 agataatcag ggagcaatta gcacggttat ttctcaattg aagcgtaaag aaagaccgac 5701 ttattctgga gatttacaag caaagtggtt attagaggaa attccatata gcaaagcgtt 5761 aagtgcccaa tattatgctg aggatgatgt cggtagtgaa ggttacatca tctttaacga 5821 tgaattggcg attataggtg tgagaggtac agagccttat tttcagagta agaaaccacc 5881 tgttgataac actaaattta aaattataaa agcggcttca ggtatggcgg ctgtgattgc 5941 ggataagata gaaagtgcta ccgattcacc aggaatgaaa gaccttatta taacagacct 6001 tgatgctgcg caaatcgccc ccgaagagtt tggtggaaca tatgttcatc gggggtttta 6061 ccaatatacg atggctttgt tatctttgat ggagaaagat ctagggctac ataaaataaa 6121 aaaattctat tgttgtggcc atagcttagg gggcgctggt gcattactta taagtgcatt 6181 gattaaagat agctatcatc ctccagtatt gcgtttatat acatatggaa tgccacgagt 6241 gggaactcgc agttttgtag agcgctatca aaatattttg cattaccgtc atgttaataa 6301 tcacgatttg gtgccacaga taccaacagt atggatgaac acagatgtat ctgaaggatt 6361 ccatgtactt gatgtattta aaagccgtgt tgatctgatg agaaaaatgc tcactgatga 6421 tgatgatgac aattatcaac accatggtca tttgtctcag ttactaactt ataattcaaa 6481 taaccaagtc ttactgacac ccaaacaaac tcaagtcact atgctagacc tagcaaattt 6541 agccactaat gattctgttg ctatggtaga tggtttatca gatgcctcaa tagtagagca 6601 tggaatggag cagcatatac ccaatttatt tgagcagtta acagcactaa gtgatgaaag 6661 tttaatggtg cattatcaac gagcgatttc agccttagag caggaaattg ctacgttgca 6721 acaaagttat cttacagtta aacaagcttg gattgaatct ataggaaatg gcacgccgac 6781 tatgaatatc ggacgtttga tgagtgaaat gcattctata aataaattaa tagagaaccg 6841 taataaaatt agaggtgagc taaggcagat agtctctgat cctcagcgta tgcctgcaac 6901 taaattttta atttcacagc aaaccttacc agatgaaatc aaggtgcaaa taagatgaag 6961 ttattgaata atcttgcaat aaaaaagcta atctcagttg ttgtactatt cattgcatta 7021 ttttttcttg ggtatgacta ttaccagact tctcaaccta atatttgggg tgatgaacct 7081 gatgagtcct atattactat atcaggcaaa aagcctatag atgcttattt agaagtgtgg 7141 actcattttt gggtgacagg agatgagtgt gaagcttatt cctacgattt atttggtcaa 7201 aaagcccatc aaggaggaaa aataagccag aagattacgc atgattttgc taaagatggt 7261 tcaaattttg aatttagaat tccttaccaa acgtataaga actcacaaaa ttgtatagtg 7321 gaattaagag acttttccat acaagctcat aatgattttg ataccgtagg ttttgctcag 7381 ttgcgatttt ctccagcagg cagagaatat tacaatcgag aggttgatct aaactcattg 7441 tttacagcag ataattgcaa tagtgatata tttaaaagta taagaaaaga gtgggcagga 7501 gccattggtt gtcattttta tgtcgatgga aagaaaaaga ctaaagatga agaattcaac 7561 gcttacacca tctactacga tttttcgaaa ttcaataatg acaccgtgat tcattacgat 7621 attttagccg gtgaaaacta tcggtcagag cctttgtcct cagctcaaaa gacagcagtg 7681 gtatctgatg ataattaatg ccggtggttc tgtaattttt aattatgagt ttaataattt 7741 caattaagct cataattgtc attgttttaa aatcctgtta cgagataaaa cacttctatt 7801 tggtgaatcg tagttagctg ataatacaat caaggaagta aaatgaaaaa attgattttc 7861 ttgttgtcgg cacttctact caactcttgt tccaccaatc ccgtatatga aacagagcaa 7921 ccatggactt ggcgagttgg tgtaacaatg ccctcttttt atccagtcaa cgttactcga 7981 gtctatggcg tgaataataa agaggattgg accgtcttaa ttcataactt tatgactttt 8041 gtgagtgata gtgatatcag ttatatccat cagatatttc ctgactatga tggttttggg 8101 ctgccacatg ccttaggtat tacaagcaga agccaaattg gtgtaggtac cacccagctg 8161 cctgatacac tctatatgta ctgggtttca ttgtttgata ccaaatttta tgtcactaag 8221 tatgagattc ctgacaacgt aaaacagtta gtagctacga aaaaaactta tactaaatgg 8281 aatggattta ttgttgatcc atgttatcgc acagagttta tttttggtct tctgcctaat 8341 gggcaagcta aggtgtggtt gagtggctgt ggtgagacta tttatttgac cgagctagca 8401 cctgaccaaa tacttgaccg cgacagtaat ggcgttaaat ttgattctta tcggaagtct 8461 tcctcttttg ttgatgttca gcaacgcgct aaggatgcag gtgttgagct agagcccatc 8521 ccttgggata aagtgaataa agtctactcg agatatgaga ttaaaacgct tggcgagtaa 8581 cttagcgtga attgaaaaat cttcataaga cacataagag gctttgcggt ataagaaagg 8641 cttgctgatt ttccttcaag gattgatatg gttatccaga atttcgaagc ttttcttatc 8701 gctattacta ttttgacttt aacaccgggg ctagatactg ctttggtgat ccgtaacact 8761 tcgcgggctg ggtttgccga tggatgcacg accagcttgg gtatctgttt tggcttattc 8821 gttcacgcca ctttttctgc tattggtatc tctgcgattc ttgctcaatc ggctgagcta 8881 tttcaaatcg ttaaaatggt gggagcggct tatctgattt ggttgggtat ttcgagccta 8941 cgatcattaa tgaaaacagg gcagggcatt gaggttgcga gcctagctca tgcacaattt 9001 cgcttaaccc gatcgctgcg tgaaggtttc ctctcgaatg tgctgaaccc gaaaactgcc 9061 gtcttttact tagcttttct gcctcaattt attaatcctg actattcacc gttagcgcaa 9121 tctttgctga tggcgttgat tcattttgcg attgcgatgg tatggcaatg tggtttagct 9181 ggtgctttga gtagcgctaa aaaccttctg aaaaacgctt cttttatgcg ttggatggaa 9241 ggtacaacgg gagttgtttt ggtcgcatta ggtatcaaac tgctcttaga gaaacctcaa 9301 gcctagcgtg taataaaggt ttaaaagtag aaaaagcgcc gttgggcgct ttttctttgt 9361 gcttagaccg actaggtgtt attgaacttg ggcttcggct tcggagtatt gataacgcgc 9421 ggcaaaatat tgcttcgttt cttctacgac cacatggcgt aaggcagcaa ggccaataag 9481 gttcggaatg gccattaaac catttacaat gtcggcgata atccaaatca aatcgaggtg 9541 taggaatgcg cctgaggcaa tcaaaccaat aaagacgatt ttataaggca ataccgcttt 9601 ggttccgaat aagaacacca tgcagcgttc gccgtagtag ttccaaccca gaatggtcgt 9661 aaaggcaaag aacatcaaac caatcgaaac cagcatcggg ccgatagttt gtgcatttaa 9721 gcctgtggca aaggcgtagg tggtcatcgc agcaccggaa aggtcgcttt gccaagcgcc 9781 cgttagaatg agagccaagc cagtcatcgt acagatgata atggtgtcaa agaaagtccc 9841 cgtcatagag ataagacctt gctcaacgca ggagtcagtt ttcgccgccg ccataggcgc 9901 actgcctaag ccagattcat tggagaacac gccgcgggca atacccgatt gaatcgcgag 9961 cataatgctc gcacctaaga agccacctgt cgcagcagtc gaggtgaaag cggataccag 10021 caccaattcc acggcgtctg cgagtttgtc tgcattggta acaatcacac ttaagcaggc 10081 gacaatgtaa aacagcgcca tcgcaggaac cacttttcct gcgactttag cgatggattg 10141 aataccaccg atagtgacaa tcgcaaccag tacggtcagt accactgcag aggcttcacg 10201 agggacgcca aaagagattt gagtggcatc taagatcgcg ttcacctgcg ggaaagtacc 10261 aatcccgaag caggcaaccc ctacggcaaa cacagcaaat aatactgcca gtgtttttga 10321 acccacacca tcacgcaggt agtacattgg cccgccgacc atttgtcctt tgtcatccac 10381 ttggcgatat ttcaccgcga gtaagcattc tgcgtatttg gttgccatac caaacagggc 10441 ggcgagccac atccagaaca gggcacctgg gccgccgagt ttgattgcgg tcgcaacacc 10501 tacgatgttt ccagtaccaa tggtggcaga aagagtagta cacaatgcgg cgaagcttga 10561 tacatcacct tgtttgtctg aagatttttc gcggccaaat accatagcta aagccgtcgg 10621 taggcgtcga aactgcagta agcctaagcg gaaggtgaaa tagacaccgg tgccgaccag 10681 aagaattaac agtggtggcc cccacactaa actatcaaca gtttgcagaa aagattgcag 10741 gttattcatg atttcccctt aaaaaataaa cataaggaga agagagaaag ggtgcgaaaa 10801 atgcacagca gagctctagc gagctcacta aaaaattggc ctttcactcc tctgtccttt 10861 tgcctgagag tttcactctg catatgcgca gagcttgctc cttcggcgac cgattaaacg 10921 gttctctcca gaggttcctc caactacagt cctcgcttat tcgttgccaa taaatagcta 10981 agaataatgc acctgaaaga tttacttctt cggcgggtta tttggctcag atgttaaaat 11041 ctggttaaca accactctcc tgcagtcttc aacggaacaa tcgtcttgaa taaaacgatt 11101 tgcaaggcgg atgctagcga aaagaaaatg tgatgtcacc tacaaaagaa atcaactgat 11161 gaaatgttgc gcaagtcttt tgctaatcca cttttctctg acgttaaact acgtataagt 11221 gttataagat aatcacgctt ggaggcggga gatggtgaga ttaattgcaa tagccttact 11281 gatagcatta gcgtttgtct tgatacgcta ccgtaccaat gaaaaattgc agaagggggt 11341 cgttatcgtc attttggcga cctttgtcac ctatacggcc ttcttgatga tttctgaact 11401 gattcgctga cgcaagagga gcgagcgtga ataaacataa tgagtttgac gacaacgaag 11461 aagttgttgt tatcgaacga agagataagc agagctatct ctatatcgcg attgctgcgg 11521 tattaggtat tgccttgggt ggcctgattg gttcctctgt caccaccagt cgttgggaga 11581 cgtcttacca aacactacaa aaccagcttg agcaactcaa taatgcgaaa gcagaagttt 11641 ctaaagcggc tgagctttct gagcaaaatc aagaggaagc gtggcaacat aaaatggatg 11701 aggctttaga gaagcaaaga gaagagtggc aggcagaggc tgtacagcgt gataaatacg 11761 ttgctgaact cgaaaagcaa aatcttaatt tagaacagca actgaacgag cagaaaatgg 11821 cattggaact ggccaataca caaaacaatc agcttaatcg tcaagccgat atgcaagtga 11881 ccatgcttga gcgttctcga gagttgttcc aacgagaact aaaaatcaaa caagaactcg 11941 agggattaca aaaagagcgc gattctctgg ttcccaagct caaagtactg aaaaaagagt 12001 gtgacattta ccttgaaggg aaatcttggg atgcgaagtc ggatgcctgt gataaacaag 12061 atgaagcgaa ttcacgggta agccaaattg atcagatgat ccgtgtgcat caaatggatc 12121 tggaagagat taaggcgctc tcagaagaga taggtttata agtgatttaa tctatcaggc 12181 tgaattaaag cgattatttt cgtcacatga cttgagcgtt cgctttttca ctctctagag 12241 tgaatcgcat tctgaagata caaaaaagcc accgtcgtcg gtggcttttt aatgggagat 12301 agaaaaggct taatcgttta cttttagctt ttggaaatac tcatcgtaaa gcacgctagc 12361 ctctcccact tcatcttgcc actcgccatt gtcaatcact gattgtggtg ggtagatact 12421 tgggtcattc gcaaactctt tgggcagtag gtcatgcgcg gttttgacgg gtgttggata 12481 gccgatttct aaggcgattt ttgcagcatt ttctggacgc agtaagaagt caatcatctt 12541 gtgggcggcc tcgatatttt tggctccggc aggaatcgag atgctgtcca tccaaaaaat 12601 ggtgcctttt tcaggccaga taatctggat tggtgcgcct tcttggcggg ccatatacgc 12661 tgagccattc cataacatac ctagtgacac ttcaccagcg aggtaagggt tggctgggaa 12721 gtcagagtta aacactaaga catttggcat cagctttttc agctcacggt aagcggcttt 12781 aatctctttg ggattggtcg tgttaggcga gtatcccagc ttactcaggg cgatatggaa 12841 gacttcacga gcgtcatcca tcagcattaa ttgacctgcc catttggcat cccacagatc 12901 gccccagttt ttgagtgatt ttttatccag catatcggtg ttaatgccga tacccgtcgc 12961 tccccagata taagggatag agaatttatt gcctggatca aaaggcttat tgagatagtt 13021 tggatccaag tctttgaaat gtgaaagttt tgaatggtca atctcttgca gcatgccttc 13081 tttgcgcatc ttagagacaa aataagtgga aggaaccaca agatcataac cagcgccttg 13141 cgttttgagc ttggcataca tgctttcatt ggattcgtag gtagagtaga taaccttgat 13201 tccggtttct ttggtaaagt cttctaggac ttcgctcggg atatattcag accagttgta 13261 gaaataaagt tcttggtctt tagccattgc attggtggtg aacaatgctg ctgcgcacag 13321 agcactcgca aacagtttat ttttcattac gttcccatag tgtatagaaa gaacctaact 13381 aggcgttgga gaggggagta taacaagata aaaaaaatag gcagcaatgg ctgcctattt 13441 gatgcttttc ttagacctta ttggccagct ttcaacttca tgaagtactc ttcatacttt 13501 actgtcttat cgccaacggc agattgccac tcaacacggt ccagatcttc ttgagatggg 13561 aacagtggcg cgacatcttg gaatttgtcg tttgaggctt taacgccagt cagataacct 13621 gtgtcgcgtg aaatttgctc tgcaatttca ggacgtaaca agaaatcgat catcttgtgt 13681 gctgcatcga cgtttttggc accagatgag atggcgaagt tatcaaccca accgataccg 13741 ccttctttcg ggaagactag cttgattggt aaaccttctt tctgcgccgc tgctgctgag 13801 ccgttccaca gcataccaag acctacttca cctgaaaggt aaggagctgc agggttatca 13861 gagttgaaaa ccagtacgtt tggcatcagc ttttgtagct ctgcatacgc ttcatcaatc 13921 tgcttgtcgc ccgttgagtt acctgagtaa cccagtttac gcagagcgat atggaatact 13981 tcacgcgtat catccatcaa catcagttga ccttttaact caggcttcca taggtcgccc 14041 cagctttgga agtcattagg atcatacatg tcggtattaa ccgcgagacc ggtaattgct 14101 acaacgtgtg gaattgagta gtcgttgttt gggtcgtaag gtttatctag gtagttggaa 14161 tctaggtttt tgaagttgct cagcttagat ttgtcaatct tttgcagcat cccttcatca 14221 cgcatttttg ccacgaagta ggtagaagga actaccagat cataaccttg attgtgcgtt 14281 ttgagttttg catacaaagt ttcatttgac tcataagttg agtaaatcac tttgattccc 14341 gtttccttgg tgaactgttc taggatgccg ctattgatat acggtcccca gttcataaac 14401 accagttcct tatcttccgc tgccgctgtg ccagacaaca gagaaagcgc acatgcgcta 14461 cctgctaaaa gagtagccag ttttttcatc gacgttagct ccaaactaaa cgttgccctt 14521 ttgggcgttg caaagaaaaa cagaatgact tccgtcattc tgtttcgcgt gtttccaaac 14581 ggacgtggat tttacttcac tttttctctt gctaacaact gtgaagcgac aacaagtacc 14641 aaagaaacca caagcatgac ggtcgccagt gcgtttactt caggtgaaat acccactttc 14701 accattgagt atatcttcaa tggcagaatt tcgtaggttg gccctgtcac aaatgaactg 14761 atgatcacat catccagaga tagggtaaag ctcagtaacc aacctgcggc aactgcaggt 14821 ttcgccagtg gcaggataat tttctttaaa atcacccatt cgccagcgcc gagatctttt 14881 gctgcttcaa gcatcttaac gtcaaagccg ttgagtcgag tgtaaaccgt caccacaacg 14941 aaaggcagac agaaagtgat gtgcgcaatc aacagagtga agaagcccag tttcgccccc 15001 atcactaaga atagagcaag tagcgaaata gccatcacga tatcgggtga catcatcacg 15061 acaaacagca tgccactcac cactttctta cctttaaatt ggtagcggaa gagggcaacc 15121 gccgtcaaac taccgatcaa ggttgctgca gtagcagaaa acacggctac gttgatggag 15181 tgccaagcgg cttgcattaa gctgtcgtta ttcatcaaag cgtggtacca cttggtggta 15241 aaaccgcccc atttgatacc aaacttgttt tcgttaaatg agtttgcaat cagaacgatg 15301 attggtaagt acaaaaataa gtacaccaaa ctcataaagc taaatctaat tgaacgtccc 15361 attagtctag ctccaccttc ttattcaaaa gtttacctgc acgatagtag gcgtacagca 15421 tgatcgccat ggccagagtc agtgcaatac tggttgcggc accaaatggc cagtcacggg 15481 cgttgagtac ttggctctta atcacgttac cgatcagtag gtttttcgca ccgccaagta 15541 ggtcagcgat gtagaacata ccgagggcag ggagcagaac cagcaaacaa ccaccaataa 15601 tgccaggcat agtcagcggt aaaatcacgc gaactaaagt ttgaaacttg ttggcaccga 15661 gatcgcgcgc cgcttcaata taagtgccat ccaatttttc gatagctgaa tagagcggaa 15721 ggatcataaa tggcaacaaa atgtaaacca gaccgatcat gacggctgtt tcggtaaaca 15781 taatgcgcag tggtgcatca ataaggccca gagacattag cgcttgatta agaatacctt 15841 gcgtgccgag tacgattttt aaaccatagg tgcggatgag tgagttggtc cagaaaggaa 15901 caataatcaa aaacagcata aatggacgcc atttttcagg cattttcgcc actatgtacg 15961 caaaaggata gccaatcact agacagatta atgttgcaac aatcgccatg tagaacgagt 16021 gcagcatcac ttttccgtat agtggatcaa gcagacgcgt gtagttttca aaggtgaatg 16081 caaacttaat caggttcgct tcatcacgag tcagaaaact ggtaccaata atcatcaggt 16141 tggggatcag tacaaacagc actaaccaac ctacgattaa ggtaacaatc gcattttgta 16201 gattaagctt tttgctcatc attgaggact acctcccagc tttcaaccca agtgacggca 16261 actttctgtc cgatagagtg atcaacatct ggatcatctt cgttaaagaa ttcgctaacc 16321 atcacacaca taccggattc cagttctacc actgattcca gagtcatgcc tttgtaggta 16381 cggtcagtca cgtgacccac aatgcctttt tcttctgact ctttgatttc ttcgatacgt 16441 aagtcttcag gacggaggag cacttgcagc ttgtcaccag ccttcacttc atcttcatag 16501 taaacaatcg actcgatacc ttcgatgtca acgcggatgc gtttttcgtc gatacgatcg 16561 atagtcgttg cttggaagac gttgatttcg ccgataaaac gagcaacaaa gagatttttt 16621 ggatcttcgt agatttcacg aggagagccg tcttgttcaa ttttgcctaa acgcataacg 16681 atgatgcgat ctgacataga cagcgcttct tcttgatcgt gagtaacgaa gataaaggta 16741 atgcctaatt gacgttgtag ttgtttgagc tcgctctgca tttgtttacg caatttgtaa 16801 tccaaagcgg agagcgattc gtcaagtagc agtactttag gtttgttaac cactgcgcgc 16861 gcaatagcga tacgttgctg ctggccacca gaaagttgat gcggtttacg ctgtgccatt 16921 tcggcaaggc gcaccatgcg tagtgcttcc ataacacgag gctcgatttc gctttgaggg 16981 actttttgca tgcgcaaacc aaaagcgacg ttttcgaaca ctgtcatgtg ggggaataga 17041 gcatagcttt ggaagaccgt attgacgtgt cgttgttcag caggaacttg agtaacgtct 17101 tgatcatcta gcagaatctg accttgatct gcagtttcaa aaccagcaat cattcttaac 17161 accgtcgttt taccacagcc cgatggacct aggatggtta agaactcgcc atgattcaca 17221 tcaagattta ggttaccaat gatttcctta ccatcgaaac ttttgctaat gccagataaa 17281 cgaatgactg gctttcctac tgaatgttgt tcgttcaacg tctgtatttc tcccacctcg 17341 gcctgtagaa aatcctactt gttggacctg tagttaaaca aaaataagag gcgcatcata 17401 aacaccaaga gcacgatttc aaagtctttt tctcaccttg aaacagaaaa atttttgcca 17461 gtttgaatag agtttgtcta gcatactgat tttgcttaac tcttaatgct atcaagcagt 17521 taattatcaa tcatatcgac aataaagcaa gatgatattg gtaatcagat tttagcctga 17581 gcagcatttc agtataatga //