LOCUS NC_008321:12 18111 bp DNA linear BCT 05-OCT-2011 DEFINITION Shewanella sp. MR-4, complete genome. ACCESSION NC_008321 SOURCE Shewanella sp. MR-4, complete genome. COMMENT locus start: 3512471; locus end: 3530581 FEATURES Location/Qualifiers source 1..18111 /organism="Shewanella sp. MR-4, complete genome." gene complement(0..659) /gene="" /locus_tag="" /db_xref="3512471..3513130" CDS complement(0..659) /gene="" /product="hypothetical protein" /translation="MAIMLVPIFDNAICIYDFEQYDSFEGKDDTYQTIDALFALPEVL NEANVPDANGGRALSTVHLHQTHPIPHLLNFKSNPLGRWILMCIFDAAVQLGFDKTRN IRKLKYHRTWANRMEYGCDAVAHRHANDDWSIPHLVAIYYTDVPENSADLVFIQDDNR QLMRGKSCSEYPLAQQYRVSSLAGRLICHDARFLHGTTVHKNTLPRTCLVIEVGFPPL D" gene complement(671..2206) /gene="" /locus_tag="" /db_xref="3513142..3514677" CDS complement(671..2206) /gene="" /product="tryptophan halogenase" /translation="MKIKRIAIIGGGTAGWLAANHLGAELCHDPEIEITLIESLDVPT IGVGEGSVPYLAKGLKRFGISEAEMLLTCDATFKQGIKFVNWLDPERHGENHYYHSFD TPYPAGVDVSNYWLANAADRPFDDVGIQARICELGLSPKRKGSGDYEGALSYAYHFNA LKFAVLLANNAKSRFKVKHQFATIKGAEVCQSGRITHLVTADDTSLAFDFYVDCSGFA SILIDKTLKVPFVSKADELLTDTVLVQQVALGADEEINPYTTATAHKAGWIWDIPLTT RRGTGFVYSSRHMSDDEALGLYADYLSIDKAQFNPRKIPMKVGYRETFWHQNCVALGL AQGFVEPLEATSILVSDFSAELLALNFPRHLEDIDVLTPHYNQVTTYVWERVVDFIKL HYCISDRTDSDFWLDNKKSETISEELHQRLARFALRPPYASDFFGRFELFDHKNFLYV LYGMKFNTAATVLSAQEVQHCDALMKGNDQLVVKAASMLLKHRDWLEGLKQAFEQARS TKV" gene complement(2269..4932) /gene="" /locus_tag="" /db_xref="3514740..3517403" CDS complement(2269..4932) /gene="" /product="TonB-dependent receptor" /translation="MRPSSFKKSVLATNIAILLGSAVSISAVAAEAEAAAAAAVPENI EKIEVRGIRASNKANINEKRFSNAVVDAVTAEDIGKFPDSDVGQALGRVPGVTVGRTF GQGSSVSIRGTDPLMTLTTLNGQNVASTGWYDQMNVDRSFNYSMLPSELIGGMEVYKS TQANLVEGGIGGTVIVKTRKPLDMDANSVFASVKGEYGSVNEDVAPELSGLYSWKNDD ETFGVLVAGSYIDREYLRTGTEADLDWGGRSSVQPSSFLQEQERTALDATVQFRPTDN LEFGAHVLSLKLGADSIGANMYIETDTNWGEGASHCKQFNAAGVCTLSVTPESDPSNV FFQNWARKGEMTSDTFELNADYKGDGFAISGVAGKTKAEGGTQMSANFGYGWWGDKFG QVKWAGTVDATGKQIDINGRDMGFTQDQLDTTVGTSTWTGIKGPNSDEETYLQLDVDF DLDFGVINKFETGVRYTQHEFEKSEYRAIYDPAKKNEFKTSDLYSGTMKLGYDGWTIP KADLDAMINATESLVDQFAYSRSAYGLIEEDNFSMYGMFSFDGEGFRGNFGLRYIQTD VTSSGHIIDNSPADVLSVNQGWSEEIHSISDSYSDVLPSFNISFDLAPDLILRMSAGQ AITRPNYDNLFLSTSTGYPDDRRGNEEITYGNPGLKPMKSSQADLSLEYYYGDGNLVS ATYFIKDISNFIVATTQYNQQIGVVNNDLETPADNWTVNNYENAGGGEIDGIELQLNH AFDNGFGVNANYTYADGTAPAEVYTDNIGMFTESSKHSANLVGYWENDDFSARAAYNW RSEYMVREYGKYYGNRMHDAFGTLDVTLGWNVTEAIALRLEIVNLTAEDDVQYGAAGV GTEVKPALQDDFPTWSFKGETTYKLGASFVF" gene 5359..6375 /gene="" /locus_tag="" /db_xref="3517830..3518846" CDS 5359..6375 /gene="" /product="transcriptional regulator, LacI family" /translation="MKVTINDVAKYAGVSIKTVSRVTNNEPSVKQATVDKVNEAIKAL NYQPNLAARNLAGTKSYAIGFIYDNPNAYYIIDMQNGILSACKDKGYELVIHPCNAKS DTICDELTQLVKHSRLAGLVLTPPLSEDPKVLKALSDIEANYVRIIAGEGNKEQDGLT ILVNDKFGAVEITQHLIDLGHKEIAFLSGDLHHESTKERLLGYKQALTKNRLLLNEDY IIEGKYSFESGVEGANTLIKQKNRPTAIVACNDEIAAGALFAARLAGLDIPGDLSIVG FEDSPFSRQTWPKLTTVHQPNAEIAQVATELLIAKRREQDAKFAKTFTPEPVIRDSSA SPKH" gene complement(6436..7725) /gene="" /locus_tag="" /db_xref="3518907..3520196" CDS complement(6436..7725) /gene="" /product="NADH dehydrogenase" /translation="LATKRIVIVGGGAAGLALASKLGRKMGGSDVVDVCLIDKSPIHI WKPKLHEVAVGVIDQSIEGLLYRDHGLKNGYRYIRGEIEQCEPDAKTIQLAAVYSDSG ELLLEPRQIEYDYLVLALGGVSNSFNTLGAEKHCIFLDSLDNANLFHQKLLDALLQLN ETQEKVSIGIVGAGATGVELAAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQ LPERVSARAQAVLDKIGIRLHIGVQVKEVTRDGFITQDGDVIEAGLKVWAAGVKGPKA FQNFSKLPITPRNQVEVDACMRVKGHQDIYALGDCALLILESGQPVPPRAQAAAQMAD TLYENIVSRLQGKAEKPFVYKDYGSLVSLSRFSAIGNLMGNLRSGTFFVEGHIARIMY ISLYQRHLASLYGWFSAIIYRIAQKLLKWQRPKLKLH" gene complement(7918..8256) /gene="" /locus_tag="" /db_xref="3520389..3520727" CDS complement(7918..8256) /gene="" /product="nitrogen regulatory protein P-II" /translation="MKKVEAIIKPFKLDDVRESLAEIGITGMTVLEVKGFGRQKGHTE LYRGAEYMVDFLPKVKIELVIQDDLVDQAIDVIVETARTGKIGDGKIFVTDVERVIRI RTGEENEEAV" gene 8494..9006 /gene="" /locus_tag="" /db_xref="3520965..3521477" CDS 8494..9006 /gene="" /product="methylation site containing protein" /translation="MKTLPHGFSLIELITTVSISTILLSIGAPSLSDFNTRFRADSNI KVIQQTLMLARNHAISFNRKVTVCALSNNQCTSNWQLGLTVFIDVNSNSQLDGNETTI FTTNAFNARDTVIYNRTLIRFQPDGLASGTNGTLKYCPSSPTSPYSRGIVVNQAGRAR LSTDANIRCG" gene 9161..9643 /gene="" /locus_tag="" /db_xref="3521632..3522114" CDS 9161..9643 /gene="" /product="methylation site containing protein" /translation="MLNKLLGFTLVELMVTIAVAAILLTIGVPSLISVYEGVRVNNNI AKIHDIMVFARNQAVSYGATIKVCASNGSACGTNWGNGIKVISPDNKDIRVIDAFNTN DSVKSNSASFTFSSEGMLSANSAVEIIYCPGGSATNSKSVNISSSGLISYGADGKSCS" gene complement(9672..9971) /gene="" /locus_tag="" /db_xref="3522143..3522442" CDS complement(9672..9971) /gene="" /product="hypothetical protein" /translation="MIRYCIALVLALPTFVFAAEPTVVMQDYKCHVTTTNGDKVLFYR WRIKDVNLNMASLPSKQKVGGDKKKFFIKEVVECVELSQEFTNENSKKIDELTLR" gene complement(9968..10411) /gene="" /locus_tag="" /db_xref="3522439..3522882" CDS complement(9968..10411) /gene="" /product="methylation site containing protein" /translation="MKKNRLQGFTLIEVMIAVVIVGILASIAYPSYIDYVVKSGRSEG VAAVMKVANLQEQYYLDNRSYALDMKSLGLDKDPFETEHGYYTVDFLSDDAKNVAAAD EPPRYIEFIITATVNPDSRQVKDTTCATITMTSAGVKGPSAECWK" gene complement(10420..13953) /gene="" /locus_tag="" /db_xref="3522891..3526424" CDS complement(10420..13953) /gene="" /product="type IV pilin biogenesis protein, putative" /translation="MFKKILCALSVTFVVIAGQIHADDTELYLVDSSVKTGKRPQILI IFDNSGSMSTEDTNVVSSYCSAADQAASNCTYPDGFATYLEGYSGYISQKGIYWNAGG IDNTSNAPTPDSPNDSRRFYADNNNCNKAKIALESRGRYTGLLREFKASGQSGKWTAL AENEGFNQGQIVDCYQDIIEGDPINPGRYKQGNTYNNFADGYPIDAKAMYTTATDSDA QKDSLDKTDFGKGSPVTLYTAHYLVWYKWVTTTTEGQNSGGTGSRLDVAKAAIDSALT DLNIDIDAGLAVFNLNYAAEGDADGGRIVSSIKQLTSANQTSLMSLINGMPAQTNTPL CETLYEAHQYFSGGDVTFGNKDANAKGNDKIDGYVPNSPPSILSTGKYTTPFKKCPDT AYIIYITDGAPTLDHSADAKVLDLTGKAEVAADYSGFEFTNDKGEKENSYLPALAAYM ANNDLVKGVTDATGIDNKQNVRTFTIGFTDGADVAAKLLEETAFRGGNPRELKNGNLV SKGYYRAATGLDLIQALDDALKSILSIDSSFTSPSIASNNFDKTQTYNSAYFAMFLPG EGPRWSGNLKKLKVNSAGEIVGPGGDTNAIDSNGNISASTCTYWNVCAAGSPDGNKVN SGGVLPILRESLKDRKLKSLSGSNIVNITATSFVSDYSQADLDWLYGVDVDDDNNSGS NTDAREDIMGDPLHSKPLAINFGKKGADLDVRVLVGTNQGLVHMFKDSDTGSNDFNIG SVKESWAFIPPELWGNVPKLRQNPPIGEHSVYGMDLSPVAYTETNENGEVNKAWVFLG MRRGGSSYYALDITTPDSPIFKWKIDSSTSGLAKLGQSWSEPLVTFIPGHETPVLIFG GGLASATGSGEAIYIVDANKGTFIHSFTADGMNSVPNKVAVLDSNNDGYTDRIYATDI AGNVWRMDLPTDEESKWSIFKFASISGIAPDNRMFFAEPTVAQTQFNNIHSENGVESY QSIPYDAVAVGTGNRTNPLDIKTNDMFYVFQDRNVVTKQYVGADVPAPLNITNLYNVT SAAPVSQDENIAFGEKRGWYYDFPSTGEKSLSASLIFNGKVYFTSFVPPTKQDVDLDA GICGFSGQGRLYVFDLHRGTRTSNTLYYEVGERVPDTPQIVIPEPEKGKEPEAYVIGV GKGECENGACKGTIKLGSGLKTNKIYYHIDE" gene complement(13957..14409) /gene="" /locus_tag="" /db_xref="3526428..3526880" CDS complement(13957..14409) /gene="" /product="type IV pilus assembly protein PilX" /translation="MRRQKGVVLFFALIVLIIMTVIGVALAVNSTQSLRMAGAGAERI EAKAIADGGLEQVIDDYSGAKLANLADVKDESVLPSSQKFETSQKLVPLPETGVRDVG CQRTTNATSADLISCRRVEVSSSVEFGRNKLGSLTVVSGVEQQVLTGN" gene complement(14422..15435) /gene="" /locus_tag="" /db_xref="3526893..3527906" CDS complement(14422..15435) /gene="" /product="Prepilin-type cleavage/methylation-like protein" /translation="MKCSRTLASTHSARTNQRGLSLVELMVAMVIGLFLTAGVFTMFS MSSSNVTTTSQFNQLQENGRIALAILERDITQLAFMGDMTGTDFIIGTNTTDEVPTLS SDCIGAGLNNGTLPNTQSAHFRRLWGYESVSSESLSCISSSNVYAGIDKKGTDVLQLK RLLGPSVAEGNDSAIFIAVNSTEAVFFVGDKPVLLPDNSRIWEYQHHVYFIANDASGI PILRRKTLTSSGMSNDEQLVEGIENIRYLYGFDNDGDSTPDSFMPAKDVTTLMWDNEG FQRLVAIKVFLLVRSINEDKTYSNDTEYQLGDKTIKAPADHYRRKILSTTIVLENPVL IRS" gene complement(15436..16002) /gene="" /locus_tag="" /db_xref="3527907..3528473" CDS complement(15436..16002) /gene="" /product="type IV pilus modification protein PilV" /translation="MTKFERLTHNRIQRGFSLIEVLVALVILVIGLIGIFNLHIVAKR GSFESFQQTQASYYATDIINRMKLNRTQLTSYEGTYNFEEPPSMAENCEAQLCSPEQM ATWDKYDWGRALFGSLEVVGGQNVGGLDTPTACVQVSGNDVLVVIVWKGIRSTNIDTS AVEDISGGCDSEAETPNRRIFSIRTVII" gene complement(16218..17174) /gene="" /locus_tag="" /db_xref="3528689..3529645" CDS complement(16218..17174) /gene="" /product="hydroxymethylbutenyl pyrophosphate reductase" /translation="MKLDPTSPSLNIMLANPRGFCAGVDRAISIVERALELFSPPIYV RHEVVHNRYVVQNLKDRGAVFVEELDQVPDNNIVIFSAHGVSQAVRAEAKARGLRVFD ATCPLVTKVHLQVTRASRKGIECILIGHEGHPEVEGTMGQYDNPNGGVYLIESPADVE TLEVRDPNNLCFVTQTTLSVDDTLDIITALQKRFPSIEGPRKDDICYATQNRQDAVRN LSADVDLLIVVGSKNSSNSNRLRELALKTGTQSYLVDTADDIDSSWFENVTKVAVTAG ASAPEVLVQQVVQAIAKLAPSVVTEVEGRKEDTVFAVPAELR" gene complement(17176..17598) /gene="" /locus_tag="" /db_xref="3529647..3530069" CDS complement(17176..17598) /gene="" /product="peptidylprolyl isomerase, FKBP-type" /translation="VTVTRSLLCHMNIVLEDGSTADSTKASGKPARLNIGDGTLSPAF EAQLVSLNLGDKHSFTLEAVDAFGESNPDAIHYMDRTRFPADMELEVGVIVSFAGPGG SEIPGIVREVAGDSITVDLNHPLAGRKVTFELDVVKVL" gene complement(17598..18110) /gene="" /locus_tag="" /db_xref="3530069..3530581" CDS complement(17598..18110) /gene="" /product="lipoprotein signal peptidase" /translation="MPLTWKDSGLRWYWVVVLVFLADQLSKQWVLANFDLFESVKLLP FFNFTYVRNYGAAFSFLSEAGGWQRWLFTLVAVGFSTLLTVWLRKQSASLWKLNLAYT LVIGGALGNLIDRLMHGFVVDFIDFYWGKSHYPAFNIADSAIFIGAVLIIWDSFFNSK SEQDKTEEVK" ORIGIN 1 tcaatccagc ggaggaaaac cgacttctat cactaaacaa gtccgaggta aggtgttttt 61 atggaccgtt gtgccatgta aaaaacgagc atcatggcaa atcaatcttc ccgccagaga 121 actgactcta tattgctgcg ccaaaggata ctcactgcat gacttaccac gcataagctg 181 ccgattatca tcctgaataa agactaaatc agcactattt tcaggcacat ctgtataata 241 aattgcaact aaatgcggta tagaccaatc atcattcgca tgcctgtgag ccacggcatc 301 acaaccatac tccatacgat tggcccaggt acggtgatac tttaactttc taatatttct 361 cgttttatca aatccaagct gtaccgctgc atcaaaaatg cacatcaata tccagcgccc 421 taaaggattg gacttaaaat ttaacaaatg aggaattgga tgggtttgat gcaagtgaac 481 cgtagataag gctcgtcccc cattagcatc aggtacgttt gcctcattta gcacttctgg 541 taacgcaaac aaggcatcaa ttgtttgata agtatcgtct ttaccttcaa aactatcata 601 ctgttcaaaa tcatagatac agattgcgtt atcaaatatt ggcactaaca ttatagccat 661 ccagattaaa attaaacctt tgtagaacga gcctgctcaa aggcctgctt taagccttca 721 agccaatctc gatgttttaa tagcattgaa gccgctttaa cgactagctg atcatttcct 781 ttcattaatg catcacaatg ctgaacttct tgtgctgata agactgtagc agccgtgttg 841 aacttcattc catacaacac ataaaggaag tttttatggt cgaacaactc aaaacgccca 901 aaaaaatcag atgcataagg aggtcttaag gcaaaacgcg caagtcgctg atgtagctcc 961 tcagatatag tctcgctctt tttattatcg agccagaaat ccgagtctgt tctatctgaa 1021 atgcagtaat gcaatttaat aaagtccacg actctttccc acacataggt cgtgacctga 1081 ttatagtgag gcgtgagcac atcgatatct tccagatgtc gagggaaatt aagtgcaagt 1141 aattcagcag aaaagtccga taccaatatc gacgttgctt ctagcggttc cacaaagcct 1201 tgcgctaacc ctaatgcaac acaattctga tgccaaaatg tttctctgta gccgaccttc 1261 attggaattt tacgcggatt aaattgagct ttatcgatgc ttagatagtc ggcgtataag 1321 cctaacgctt cgtcatcact catatggcga ctagaataca caaaaccagt accacgccga 1381 gtcgtgagtg gaatatccca aatccagcct gctttatggg ctgtcgctgt ggtgtagggg 1441 ttaatctcct catcggcacc cagtgcaacc tgctgaacga gtactgtatc agttagtaac 1501 tcatcagctt tactcacaaa aggcactttg agggttttat caattaagat tgaagcaaat 1561 ccactgcaat ccacataaaa atcaaatgcg agtgaagtat catccgcagt cactaaatgg 1621 gtaattcggc cggattgaca aacttcggca cctttaatcg tggcaaattg atgctttacc 1681 ttaaatctcg acttggcgtt gttagcgaga agaactgcaa atttcaaggc gttgaagtga 1741 taggcatagg acagtgcgcc ttcataatcg ccagaacctt tacgtttagg cgataatcct 1801 aactcacaaa tccgagcttg gatcccgaca tcatcaaagg gccggtcagc agcatttgcc 1861 agccaataat tcgatacatc gacacccgcg ggataggggg tatcaaaact atgatagtaa 1921 tgattttctc catgtcgttc tgggtctaac caattaacaa atttaatccc ttgcttaaaa 1981 gttgcatcgc aagtcagtag catctcagcc tctgaaatac caaaacgttt cagccctttg 2041 gcaagataag gcacacttcc ttcccccacg ccaatggttg gtacgtctaa agattctatc 2101 agggtgatct cgatttccgg gtcgtgacat aactctgcgc ccaaatggtt tgcggctaac 2161 caacccgctg ttccgccacc aataattgca atgcgtttga ttttcatcgg ctttgactca 2221 tctataaaaa agcccagtcg agactgggct tttagactaa aacaacatat tagaatacaa 2281 aacttgcgcc taacttgtag gtagtttcgc ctttaaacga ccatgttggg aaatcgtctt 2341 ggagtgcagg tttaacttct gtgcctacgc cagccgcacc atattgcaca tcgtcttcag 2401 ctgttaagtt aacaatttca agacgtaaag caatggcttc tgtaacgttc caacctaaag 2461 tcacatccag agtaccaaag gcatcgtgca tgcggttacc gtagtatttg ccgtattcac 2521 gaaccatata ctcagaacgc cagttataag ctgcacgagc tgagaaatca tcattttccc 2581 agtaacccac taagttcgca ctgtgcttag aagactcagt gaacataccg atgttatcag 2641 tatacacttc ggcaggagcg gtaccatctg cgtaggtata gttagcgtta acaccgaaac 2701 cattgtcgaa agcgtggttt aactgtaact cgataccatc gatctcacca ccacccgcgt 2761 tttcataatt gtttacagtc caattatcgg caggggtttc taagtcattg ttcactacgc 2821 caatctgttg attgtattgg gtagtagcaa caatgaagtt actgatatct ttgataaagt 2881 atgtagcaga aactaagttg ccatcaccat agtagtattc aaggcttaag tcagcttgtg 2941 aagacttcat tggctttaag ccaggattac cgtaggtgat ctcttcgtta ccacgtctat 3001 catctggata accagttgat gttgataaga ataagttatc gtagttagga cgagtaattg 3061 cttgtcctgc tgacatacgt aagatcaagt caggtgcaag gtcgaaagaa atgttaaagc 3121 ttggcaatac atcactgtag ctgtcgctga tgctatggat ttcttcgctc caaccttggt 3181 tcacacttaa aacgtctgcc ggcgagttat cgatgatatg accgctagaa gtcacgtcag 3241 tttggatgta gcgtaaaccg aagttaccac ggaagccttc accgtcgaat gagaacatac 3301 cgtacatcga gaagttatct tcttcgatca ggccgtaagc tgaacggcta taagcaaatt 3361 ggtcaactag agattctgtc gcgttgatca ttgcatcaag gtcggcctta ggaatagtcc 3421 aaccgtcata gcctaacttc atggtgccgc tgtaaagatc tgaagtcttg aactcattct 3481 tcttagctgg gtcgtaaata gcacggtatt cactcttttc aaattcatgt tgagtgtaac 3541 gcacgccggt ttcaaactta ttgataacgc caaaatctaa gtcaaaatca acatctaact 3601 gcagataagt ttcttcgtca gagttaggtc ctttgatacc agtccaagtt gaagtaccaa 3661 cagtagtgtc tagctgatct tgggtgaatc ccatgtcacg gccattgatg tcaatttgct 3721 tgccagtcgc atcaacggta cccgcccatt tcacctgacc aaacttgtca ccccaccaac 3781 cataaccaaa gttagcactc atctgagtac cgccttcagc cttagtttta cctgctacac 3841 cagagatagc aaaaccgtca cctttataat ccgcatttaa ctcaaaggta tcagatgtca 3901 tttcaccttt acgtgcccag ttttggaaga acacgttaga tgggtcactt tctggagtta 3961 cgctcagagt acacacaccc gcagcgttaa actgtttaca gtgagaagct ccttcacccc 4021 agttagtgtc ggtttcgata tacatgttgg caccaatact atcagcacca agcttgagtg 4081 atagtacgtg agcaccaaat tctaaattgt ctgttggacg gaattgcact gttgcatcga 4141 gcgcagtccg ctcttgttct tgcaggaagc tagagggttg aaccgaagaa cggccgcccc 4201 agtcgaggtc cgcttcagta ccagtacgca gatattcacg gtcaatgtat gacccagcga 4261 ctaaaacacc gaaggtttca tcgtcatttt tccagctata taaaccagat agctcaggtg 4321 caacatcttc gttcactgaa ccgtattcac ctttaacaga ggcaaataca gagttcgcat 4381 ccatatctaa cggtttacga gtcttaacaa tcacagtacc accgatacca ccctcaacga 4441 ggttagcttg ggtagactta tacacttcca taccaccaat cagttctgat ggcagcatag 4501 agtagttgaa tgaacggtct acgttcattt gatcatacca acctgttgat gcaacgtttt 4561 gaccattcaa agtagtcaac gtcattaacg gatcggtacc acgaatagaa acagagctac 4621 cttgaccaaa tgtgcggcca acagtcacac caggaacacg tcctaaagct tgacctacgt 4681 cagaatcagg aaatttaccg atatcttcag ccgttaccgc atcaacaact gcatttgaaa 4741 atcgtttttc gttgatattg gctttgtttg aagcacgaat accgcgcact tcaatctttt 4801 caatattttc aggtaccgct gctgcagcgg ctgcttcagc ctctgcagca acagcactga 4861 ttgaaacagc gctgccgagt aggatagcaa tgtttgtagc tagtacactt ttcttaaagg 4921 atgatggtcg catctcgttt cccttccata actttattat cgttttagta ttcataacca 4981 ttccgatgga atgacaacgc tgtcatgtct agtgcaaaca ttacacaata attaacagcc 5041 ttgccacaac aaaataactc tggacgaaaa aaaatgtcat aaagcgaagt gttgagaagt 5101 gaaaaatcaa tatattttag caaaaataat cacttagata ttttgatgta aaattacaac 5161 ttacaaccga gtgttaacag ttgaaaaatg cctcagtttg taacaattca gcattgctat 5221 acgcggtaaa tgctcgcact ataagaagca taataaaaag taagctgaca acgctgtcgg 5281 cttgtaaatt gcgcctaaag gatttaggtt catcaattag ctagcccttc gcacatttga 5341 ataaagagtt tgtagatcaa tgaaagtcac tatcaacgac gtcgctaaat atgctggagt 5401 gtcaatcaag acagtttccc gcgtaaccaa taacgaacct tcggtaaaac aagccacggt 5461 tgataaagtg aacgaggcca tcaaggcatt aaactaccag cccaatctcg cggccagaaa 5521 ccttgctggc acaaaatcct atgccattgg ttttatttat gataatccca acgcttatta 5581 cattattgat atgcaaaacg ggattttgtc ggcctgtaaa gataaaggct atgagctggt 5641 tattcatcct tgtaacgcca aatctgacac catttgtgat gaactgactc aactcgtgaa 5701 acattcgcga ctggctggtt tagtgttaac accgcctctt tctgaagatc ctaaagtact 5761 taaagcctta agtgatattg aggccaacta tgtgcgaatt attgccggcg aaggtaataa 5821 ggagcaggat ggactgacga ttttagtcaa tgacaaattt ggtgcggttg agattactca 5881 gcatttgatc gacttaggcc ataaagaaat tgccttttta agtggtgatc tacaccacga 5941 gtctaccaaa gagcggttac ttggttataa acaagcatta acaaaaaatc gcctgcttct 6001 gaatgaagat tacataattg aaggaaaata ttcatttgag tcgggtgtag aaggggctaa 6061 caccctgatc aaacagaaga accgtccaac agcgattgtt gcctgtaacg acgaaattgc 6121 agcaggggca ctttttgctg ctcgtttagc agggctagat atccctggcg atctatccat 6181 tgtcggcttc gaagacagcc cattctcacg ccaaacctgg ccaaaactaa caacagtgca 6241 tcaacctaac gctgaaattg cccaagtggc aacagagctg ttaatcgcga aacgccgtga 6301 acaagatgcc aagtttgcaa aaacatttac gccagagcca gtgatccgag actcttcagc 6361 ctctcccaaa cattaatttt cagccctgca aggctaaaac aaaacagaga gccaaggctc 6421 tctgttttgt ttttagttaa tgcaatttca gctttggcct ttgccatttc agcagctttt 6481 gcgcaatgcg ataaataatt gcggagaacc agccatatag gctcgctaag tgtctttggt 6541 ataacgaaat atacatgatc cttgcgatat gaccttccac gaagaaagtc ccagaacgca 6601 aattccccat tagattaccg atcgcagaaa aacgacttaa agacaccaga gaaccatagt 6661 ctttatacac aaaaggtttt tctgccttcc cttgcaaacg gctcacaata ttctcataca 6721 gggtatccgc catttgtgct gccgcttgag cgcgcggtgg cacaggttga cccgactcca 6781 aaattaatag agcgcaatcc ccaagtgcat aaatgtcttg atggccttta actcgcatac 6841 aagcatcaac ttccacttga ttgcgtggcg taatgggtaa cttagagaag ttttgaaacg 6901 cttttggacc tttcacacca gccgcccaca ctttaagtcc cgcttcgata acgtcaccat 6961 cctgtgtaat aaagccatcg cgggtgactt ccttaacctg caccccgata tgcaaacgga 7021 tgccaatttt atccaatacc gcttgagctc ttgcgctcac acgttcgggt aactgtggga 7081 gaattttggg agaggcttca ataagatgca catcaagatg atgcttagag atattgaggt 7141 agccatactc tttcaccgat tcaatgacat ggtgaagctc tgcggctaat tcgacaccag 7201 tggcacctgc gccaacaata cctatactta ctttctcttg tgtttcattg agttgcagta 7261 atgcatccaa taatttttga tggaataagt tagcgttatc taaactatca aggaaaatac 7321 aatgcttctc agcacctagg gtattaaagc tattagagac cccgcctaag gctagcacta 7381 agtaatcgta ttcaatttga cggggctcaa gcagcaattc acccgagtca ctataaaccg 7441 cagcaagttg gatggttttg gcatcgggtt cacattgctc aatttcgcca cgaatgtatc 7501 gataaccatt cttaaggcca tgatctcgat acaacaatcc ctctatagac tggtcaataa 7561 ccccaacagc tacttcgtgt aattttggct tccaaatatg gattgggctt ttatcaatta 7621 agcaaacatc gacgacatca ctaccgccca tcttgcggcc taatttagag gctagcgcta 7681 aacctgccgc cccaccacct actatcacga ttcgtttcgt agccaaaata acaacctcaa 7741 caagcctatt taagtggcta agttatacca tggaacagat aagagataac tactttagtc 7801 taactaaaga ggcaattttg cattaaagat atttcaggaa cagaaagact tagtcccatt 7861 aatcataaat tttaagcaac aaaaaagggc ctaatggccc tctctttaaa cggataaatc 7921 acaccgcttc ttcgttttct tcaccagttc gaatgcggat aacacgttct acatcggtta 7981 cgaaaatctt accatcgccg attttacctg tacgagctgt ttccacaata acatcaatcg 8041 cttggtcgac taaatcatct tgaatcacga gttcaatttt cactttaggt aaaaagtcga 8101 ccatatactc agcaccacgg taaagctcgg tgtgcccttt ttgacggccg aagcctttga 8161 cttcaagcac tgtcatcccc gtgataccta tctcagcaag tgactcgcgt acatcatcca 8221 atttaaaagg cttaataatc gcttcaactt ttttcatcaa acattcctcg gcacttgctg 8281 acagataatc aaatagaatg ccattagctt acacggggtt aggcgattat tgaagtatag 8341 gtagcgcttt cctcataaaa cacagtttct ataaaacaat tcttagtccg taaaaatcta 8401 aaaggctcat tggtgcgctt ctatactata acagcagcag ttttgctcca aaggctcgta 8461 ggatgcgagc gacatttata acaaaggaac tgttatgaaa actctaccac atggctttag 8521 cttgattgaa ctcatcacta cggtatccat ttctaccatt ctgttatcga ttggtgctcc 8581 ctcgttaagc gatttcaaca cgagattcag ggctgatagt aatatcaaag tcatccagca 8641 aacactgatg ctcgcccgaa atcatgctat ttccttcaat cgaaaagtga ctgtctgtgc 8701 cttaagcaac aatcagtgca catctaactg gcagcttggt ttaacagtat ttattgatgt 8761 taacagcaat agtcaactcg atggcaatga aacgactatt tttaccacta acgcttttaa 8821 tgccagagat acagttatct acaatcgaac cttaattcgt tttcaaccag atggtcttgc 8881 ctctggtact aatggaacat tgaagtattg cccatcaagt cccaccagcc catactcacg 8941 agggattgtg gtaaatcaag ctggcagggc aagactatcg actgatgcca atatccgctg 9001 cggataaatg gcgagaattg atagaggcca atatcaactg acaacataaa aggattgaga 9061 ctatctttta gaatttaaac agcacaaagg atgcaactta gatactgaaa tcccgcctat 9121 tctcgcttat actttagttt gtataagtga gggttgagtg catgctaaat aaattgcttg 9181 gtttcacact ggttgaactg atggttacta ttgcagtggc tgcaatatta ttaactatcg 9241 gagtaccatc tttaatatcc gtctatgaag gtgtgcgcgt taataataat atcgccaaaa 9301 ttcatgacat tatggttttt gccagaaatc aagccgtcag ttatggcgca acaattaaag 9361 tttgcgcatc aaatggaagt gcatgtggta caaattgggg aaatgggatt aaagtgatca 9421 gccctgataa taaagatatt cgcgttattg acgcattcaa tacaaatgac agtgtaaaaa 9481 gcaattcggc gagttttacc tttagctctg aaggcatgtt atcagcaaac agcgctgtag 9541 aaatcatcta ctgccctgga ggctccgcga caaactccaa gagtgtaaac ataagctcta 9601 gcggactaat ctcctacgga gcagatggta aaagctgttc atgagccaga agatatgtcc 9661 gcacacataa gcttatctca aggttagctc gtcaattttc ttactgtttt cattagtgaa 9721 ctcttggcta agctcaacac actctactac ctctttaata aagaatttct ttttatctcc 9781 acctactttt tgcttgctag gaagactagc catgttcaaa ttgacatctt taatcctcca 9841 tcgataaaac agtactttat caccatttgt cgttgtgaca tggcatttgt aatcctgcat 9901 aacaactgta ggttccgcag caaacacaaa tgtaggcaaa gctaatacta aagcaataca 9961 atatcttatc atttccaaca ctccgcagaa ggccccttta caccagcaga tgtcatcgta 10021 atagttgcac aggtagtatc ttttacttga cgactatcag gattcactgt ggcggtgatg 10081 ataaattcta tatatcttgg aggttcatcg gctgccgcta catttttagc atcatcagaa 10141 agaaaatcta ccgtataata cccatgctcc gtttcaaacg gatctttatc taaacctaga 10201 gatttcatat ctaaggcata tgagcgatta tccaaataat actgctcttg aagatttgca 10261 accttcatca ccgccgcaac accttcagac cgtccactct taaccacgta atcaatgtat 10321 gagggatatg ctatcgaagc caaaatcccc acaataacaa cagcgatcat gacttcaatt 10381 aaagtgaacc cttgcagtct attctttttc attaatgttc ttactcatca atatgataat 10441 aaattttgtt agtttttaaa ccactaccta acttaatggt acctttacac gcgccgtttt 10501 cgcactcacc tttaccaaca ccaatcacgt aggcttcagg ttcttttcct ttttctggtt 10561 caggaataac aatttgtggg gtgtcaggaa cgcgctcacc aacttcataa tacagagtgt 10621 tagatgtcct agtacctcta tgtaaatcaa acacatacaa tcggccttgg ccggagaaac 10681 cacaaatacc tgcatcaaga tcaacgtctt gtttcgttgg aggaacaaac gatgtaaagt 10741 acacttttcc attaaaaatc aatgaggcag aaagactctt ctcacctgtc gatggaaagt 10801 cataatacca acctcttttc tcaccaaatg caatattttc atcctggctt acgggagcag 10861 cagaggtgac attgtataaa tttgtaatat tcaatggagc aggaacatct gcacccacat 10921 actgcttagt taccacgttt ctatcttgga acacataaaa catatcattc gttttgatat 10981 ctagtgggtt agttctattg cctgttccca ccgcgaccgc atcatatgga atactttgat 11041 aagactccac accattctcg gaatgtatat tattaaattg agtctgggcg actgttggct 11101 cagcgaaaaa cattcgatta tcgggtgcaa taccactaat agaggcaaat ttaaatatgc 11161 tccatttaga ttcttcatct gttggtaaat ccatacgcca tacattacca gcaatatcag 11221 tggcataaat acggtcagtg taaccatcat tattgctatc taacacagca accttattcg 11281 gcacactgtt cattccatcg gcagtgaaac tatggataaa agtcccctta tttgcatcaa 11341 caatataaat ggcttcacca cttccggtag ccgaagctaa ccccccaccg aatatcaaca 11401 caggcgtttc gtgacctgga atgaatgtca ctaaaggttc agaccaagat tggccaagct 11461 ttgcgagacc actggtagat gaatcaattt tccacttaaa gattggcgaa tctggagtgg 11521 tgatatcgag ggcataatat gaacttccac ctcgacgcat acctaaaaac acccatgctt 11581 tattaacttc accattttca ttggtctcag tatatgccac gggtgacaaa tccataccat 11641 aaacactatg ttcacctata ggtggatttt gccttaattt agggacattt ccccataatt 11701 caggagggat aaatgcccat gactctttaa cgctaccaat attgaaatca ttgctgccgg 11761 tatcggaatc cttaaacatg tgcactaagc cttggttagt gccaaccaat actcgcacat 11821 ctaaatcagc acctttttta ccaaagttaa tcgctagcgg cttagaatga agcggatcgc 11881 ccataatatc ttctctagca tccgtattgc tgccactatt gttatcatca tcaacgtcga 11941 caccgtataa ccaatcaaga tcggcttgtg aataatcact aacaaaactt gtagcagtaa 12001 tattaacaat attactgcca ctcaatgatt taagcttacg atccttaagg gattctctta 12061 atataggtaa cactccgccc gaattaactt tatttccatc tggcgaacca gcggcacaaa 12121 cattccaata agtgcaagtt gaagcagaga tattaccatt gctatcaatt gcatttgtgt 12181 caccacctgg gccaacaatt tcacccgctg aattcacttt caattttttt aaattgccgc 12241 tccagcgagg gccttctcca ggtaaaaaca tcgcaaaata agccgagtta taggtttggg 12301 ttttatcaaa attattactg gcaatgcttg gagaagtgaa ggaagagtcg attgataaaa 12361 ttgactttaa tgcgtcatcc aaagcttgaa tcaaatccaa tcctgttgcg gctctatagt 12421 agcctttaga gaccaaattc ccatttttaa gttctcgtgg attccccccc ctaaaagcgg 12481 tttcttccag caattttgct gcaacgtcag caccatcagt gaaacctatg gtaaaagtac 12541 gcacattctg cttgttatca attccagtag cgtctgtaac acctttaact aggtcattat 12601 ttgccatata ggcggctaaa gcaggaagat agctgttttc tttttcacct ttatcatttg 12661 taaactcaaa tccagagtaa tccgcagcca cttcagcttt gcctgtcaaa tcgagtactt 12721 tagcatcggc cgaatgatct aatgttggtg caccgtcggt aatgtagatg atataagccg 12781 tatcgggaca ttttttaaat ggcgtagtgt atttacctgt agataagatg cttggcggac 12841 tattaggcac atatccatca attttatcgt ttcctttcgc attagcatcc ttattgccaa 12901 aagtcacatc accaccacta aaatattgat gggcttcata taatgtttca catagtgggg 12961 tattagtttg tgcgggcata ccattaatca aggacatcag cgatgtttga ttcgcgctgg 13021 ttaattgctt aatggacgat acgatgcgac caccatcagc atccccttca gcggcgtagt 13081 tgaggttaaa gaccgccaga ccagcgtcaa tgtctatgtt taaatctgtt aaggccgagt 13141 caattgcggc tttagccaca tcaagtctag agcctgttcc gccgctattt tgtccctcgg 13201 tagtcgtagt cacccactta taccaaacca aataatgcgc ggtatataaa gtaactggcg 13261 atcccttacc aaaatccgtt ttatctaaac tatctttttg agcgtcacta tcggtggctg 13321 tggtatacat tgcttttgca tcaatgggat atccatcggc aaagttattg taagtatttc 13381 cctgtttata cctaccgggg tttatgggat caccctcaat aatatcttga tagcaatcaa 13441 caatttgccc ctggttaaaa ccttcgtttt cagccaatgc cgtccatttg ccgctttggc 13501 cactcgcctt aaactccctt aacaacccag tgtaacgccc ccgtgactct agggcgattt 13561 tggccttatt acagttattg ttatcggcat aaaaacgacg ggaatcatta ggtgaatctg 13621 gtgttggggc gttactcgta ttatcaattc ccccggcatt ccaataaatc cctttttgac 13681 tgatatagcc tgaataaccc tctaaatagg tagcaaaccc atctggataa gtacagttac 13741 tcgcagcttg gtcagctgct gagcaatagg aactgacaac attagtatct tcagttgaca 13801 tactgcctga gttatcaaag ataatgagta tctgcggacg cttgccagtt ttcacactcg 13861 agtcgactag atatagctcg gtatcgtctg catggatttg ccctgcaatg accacaaaag 13921 taacactcag ggcacacaat atttttttaa acataaatta gtttcccgtt agcacttgct 13981 gctcgacacc agagacaacc gttagagaac cgagcttatt ccgtccaaat tctacggaac 14041 tactcacttc tacccgccta cagctaatca aatctgcact ggttgcattt gttgtgcgct 14101 gacaccccac atcacgaaca ccagtttcgg gtaatggtac taatttttga gaggtctcga 14161 atttttgaga ggaaggtaaa acggattcat ccttaacatc ggctaaatta gcaagttttg 14221 caccagagta gtcatcaata acttgttcca gcccaccatc tgcaatcgct tttgcttcaa 14281 tccgctcagc tccagcccca gccattcgaa gagattgtgt tgaattaaca gctaaagcaa 14341 cgcctatcac tgtcattatg ataagcacaa tcagtgcaaa aaatagtaca acacccttct 14401 gccttctcat cttaatcctc aattagctac gtattagtac agggttttct aatacgattg 14461 tcgtcgataa tattttacgg cggtaatggt cagcaggagc cttaattgtt ttatcgccta 14521 attgatattc tgtatcattg ctgtaggttt tatcctcatt gattgaacga accagtagaa 14581 ataccttaat cgccactaaa cgctgaaatc cttcattatc ccacataagc gttgtgacat 14641 ctttagctgg cataaaactg tccggagtac tatcaccatc attatcaaat ccatataaat 14701 accgaatatt ttcaatcccc tcaacaagct gttcatcgtt gctcatacct gaactcgtta 14761 aagttttacg ccgtaggata ggaataccac tagcatcatt ggcaataaaa tagacatggt 14821 gttggtactc ccaaattcgt gaattatcag gaagtaaaac cggcttatcg cctacaaaaa 14881 acactgcttc agtcgagttt acagcaatga aaatggcgga atcattcccc tctgcaacac 14941 ttggcccgag taagcgttta agctgcaata catcagtgcc ttttttatct atgccagcat 15001 aaacattaga acttgaaata cagctcaaac tttcagagga tactgactca taaccccaaa 15061 gccttctgaa gtgtgcggat tgagtattag gcaaagttcc gttattcaag cctgcaccta 15121 tacaatctga tgacagagta ggcacttcat cagtagtatt cgtgccaata ataaaatcgg 15181 tacctgtcat atcccccata aaagctagct gggtaatatc gcgttctaat atagctaaag 15241 caatacggcc attttcctgc aattgattaa actgactagt ggtggtgaca ttagaagaag 15301 acatactgaa catcgtaaaa acgccagcag ttaaaaacag accaataacc atggcaacca 15361 ttaactcgac gagtgataaa cctcgttggt tggttctagc tgaatgagta gaggctaacg 15421 ttcttgaaca tttcatctat ataatcactg ttcttattga aaaaatacga cgatttggcg 15481 tttccgcctc tgaatcacat cccccagata tatcctcaac tgctgaagta tcaatgtttg 15541 tgctacggat ccctttccaa acgatcacaa ctaaaacatc atttccacta acctgcacac 15601 aagctgttgg agtatctaac cctccaacat tttgcccccc aacaacctct aaagaaccaa 15661 ataaagcacg gccccaatcg tatttgtccc atgtcgccat ttgctcagga gaacatagct 15721 gagcttcaca attctccgcc atagaaggag gttcttcaaa attatatgtt ccctcataac 15781 tagtcagctg ggtacgattg agcttcattc tattaatgat gtcagtggca tagtaagatg 15841 cttgagtctg ttgaaatgac tcaaagctgc cgcgtttagc cacaatgtgt aaattaaaaa 15901 taccgatcaa gccaatcact agaatcacca atgcgacaag cacttcaatt aaagagaagc 15961 cccgttgaat tctgttatgc gtcaatcgtt cgaatttagt catatttttg acaagctttt 16021 cagctattta cccttttaaa tcttaatctt acgataaaaa tattgctagc agttaataat 16081 agatgagtaa aatgtaagta gccagtaaca atagcatata agcgctaatt ccattattcc 16141 ttgtttgtat ttggtgaatt ttgataataa aaaagaggcc attggcctct tttttattat 16201 catattgatt cgaatgaact agcgtaattc cgcaggtacg gcaaagacgg tatcttcttt 16261 acgcccttca acttcggtga cgacactcgg tgctaatttt gcaatcgctt gaaccacctg 16321 ctgaaccagc acttctggtg ccgatgcgcc agcggtcacc gcaactttag tcacattttc 16381 aaaccaagat gaatcgatat catccgcggt atcaaccaga taagattgag ttccggtttt 16441 taatgccaat tcacgcaagc ggttagagtt agaactgttt ttcgaaccga ccacaattaa 16501 caaatccaca tcggccgata aattacgcac tgcatcctga cggttttgcg tcgcataaca 16561 aatatcatcc ttacgtggac cttcaatcga aggaaaacgc ttttgcaatg ccgtgataat 16621 atcgagggta tcatctaccg agagcgtcgt ttgagtcacg aagcagaggt tatttggatc 16681 acgaacttct aaagtttcga catctgcagg agattcaatc agataaacac caccattagg 16741 gttatcgtat tgccccatgg tgccttccac ctctggatgt ccctcatggc caatcaaaat 16801 gcattcaatc ccctttcggc tcgcacgggt gacctgcaaa tgcactttgg tgactaatgg 16861 acaagtcgca tcgaaaactc gcagcccacg cgccttagcc tcggcacgca ctgcctgaga 16921 aactccatga gcactgaaaa taacaatatt gttatctggt acttggtcta actcttcaac 16981 aaaaacggca ccgcggtcct tcagattttg cactacatag cggttatgca cgacttcatg 17041 gcgaacataa atcggcggcg aaaataactc gagtgcgcgc tcgacaatac taatggcgcg 17101 atccacacca gcacaaaagc cgcgaggatt ggccagcata atatttaaac ttgggctggt 17161 aggatctaat ttcatcttac agtaccttca ccacgtcgag ttcaaatgtc actttgcgtc 17221 ccgctagagg gtgattgaga tcgaccgtaa tcgaatcgcc agcaacctca cgcacgattc 17281 cggggatctc actgccgcca gggcctgcga aactgacgat aacaccaact tcaagctcca 17341 tatcggctgg gaagcgggtt ctatccatat aatgaatcgc atcgggattt gactcaccaa 17401 aggcatcgac cgcttcaagc gtaaagctgt gcttatcgcc tagattcaag gaaacaagtt 17461 gcgcttcaaa tgcagggctt aaagtaccat cgccgatatt aaggcgtgct ggcttacccg 17521 aggctttagt gctatcggcg gtcgaaccat cttcaagcac aatattcata tggcacaata 17581 acgaacgtgt cacagtcact acttcacctc ttcggtttta tcttgttcgg atttgctgtt 17641 aaaaaacgaa tcccaaatga tcagcactgc gccgataaaa atcgcggaat cggcgatatt 17701 aaaggcggga taatggctct taccccaata aaaatcgata aaatccacca caaaaccgtg 17761 catcaatcga tcgattaagt tacctagggc gccaccaatc actaaggtgt aagccaagtt 17821 taacttccag agggatgccg attgcttgcg cagccacaca gtcaacaagg tactgaaacc 17881 aacagccact aaggtaaata accaacgttg ccaaccgcct gcttcactta aaaagctaaa 17941 tgcggcgcca tagttacgta cataggtgaa attaaaaaaa ggtaataact tcaccgattc 18001 gaacaaatca aaattggcta agacccattg tttggatagt tgatcggcca aaaacaccaa 18061 tacaactacc caataccaac gtaagccact gtctttccaa gttaatggca t //