LOCUS       NC_004557:12           17600 bp    DNA     linear   BCT 18-AUG-2011
DEFINITION  Clostridium tetani E88, complete genome.
ACCESSION   NC_004557
SOURCE      Clostridium tetani E88, complete genome.
COMMENT     locus start: 1553000; locus end: 1570599
FEATURES             Location/Qualifiers
     source          1..17600
                     /organism="Clostridium tetani E88, complete genome."
     gene            complement(27..614)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1553027..1553614"
     CDS             complement(27..614)
                     /gene=""
                     /locus_tag=""
                     /product="hypothetical protein"
                     /translation="MITRKEAWDLLNEYNKEAFHIQHALTVEGTMKYFAEKLGYEDEV
                     EFWSMVGLLHDLDFEIYPEEHCIKTQEIMRQRGLDEKLIRAAASHGYGLCQGELPKPE
                     HQMEKVLFAVDELTGLIGAAARMRPSKSVMDMEISSLKKKFKDKKFAAGCSRDVIKKG
                     AEMLGWELNKLFEETILAMRSCEAYINDEMEVYNN"
     gene            694..1401
                     /gene=""
                     /locus_tag=""
                     /db_xref="1553694..1554401"
     CDS             694..1401
                     /gene=""
                     /locus_tag=""
                     /product="putative transcriptional regulatory protein"
                     /translation="MQNKIFLFILVFLVSFKQLLYNSLRTLNIFNVNFILLSLVIIVN
                     TIIGGYTIMNINSIIAENLKTLRTERNLSLGQLAELSGISKVMLSQIEKGDTNPTINT
                     LWKIAKGLKVPYTSLLEQKKHDTYVIKKRNIEAQFTEEGHYRVYCYYTSTPYRNFELF
                     QIEIDEGCSYKSIGHSKKCQEYIMVLEGELTLEINNKIYKLTSDDSISFSASSQHIYI
                     NSGNGTLKATITNFYPA"
     gene            complement(2658..3308)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1555658..1556308"
     CDS             complement(2658..3308)
                     /gene=""
                     /locus_tag=""
                     /product="hypothetical protein"
                     /translation="MDNCEELLKLLLEAVKSQGLNTEVNKNSSEIPVGISNRHIHLSQ
                     RDLDILFGNGYELVKIKDLSQPGQYACNETVTICGPKGAIEKVRILGPVRGKTQVEVL
                     TGDCIKLGVVPHVRLSGDLKDTSRITIVGPKGSIQVEEGLIVAQRHIHMTPEDAKYLG
                     VHDGEIVSIKFEDLRGGIYNNVAIRANNTSKLECHIDIEEANAMGITSKSKVTIVK"
     gene            complement(3308..4906)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1556308..1557906"
     CDS             complement(3308..4906)
                     /gene=""
                     /locus_tag=""
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /translation="MEKYDKDLYSIQQARNLARLGKVAANKIANYTEEQIDKILRNMV
                     RVAEENAVSLAQMAVEETGFGKVEDKTYKNHLAATILYDSIKDMKTIGVISEDKVNKM
                     IEIAEPVGLIMGIVPSTNPTSTAIFKSIIAIKSRNAIVFSPHPAAAKCTIRAVELMRD
                     AAIEAGAPEDIIASLTNLTMEATNELMKNENVSLIIATGGPGMVKAAYSSGKPAIGVG
                     AGNSPAYIERTANVEKAIRDIISSKSFDYGTICASEQSIICEECNHDAVVEELKKQGG
                     YFMTAEETEKVCKLLFKNGHTMNAKFVGRSPQVIANAAGFTVSEDIKVLIGKQNGVGN
                     GNPLSFEKLTTVLAFYTVKDWHEACELSIELLQNGIGHTMSIHTQNDDIVMEFAKKPA
                     SRILVNTGGSQGGTGASTGLKPAFTLGCGTWGGSSVSENVTPEHLINKKRVAYGLKDC
                     ATLVQNDPTFNCIKTASNCRGVKNQFMNMSPAQIAAAAEVLNKCNDYAKNTGCSNESK
                     EKDANNEELLSLVNQIVAAMKGAN"
     gene            complement(4941..5630)
                     /gene="ccmK"
                     /locus_tag="ccmK"
                     /db_xref="1557941..1558630"
     CDS             complement(4941..5630)
                     /gene="ccmK"
                     /locus_tag="ccmK"
                     /product="carbon dioxide concentrating mechanism protein
                     ccmK
                     homolog"
                     /translation="MQALGLIETKGLLAAVEAADVMVKSADVSIIEKTYVGGGLVTIS
                     VTGDVGAVKASIEAGAAAVKNLNEEFLVSEHVIPRPHEELESIIGSNNLQEDSSSNED
                     TSSVENVEKAEVVETTEALEEEQIVEDIYDSKNLKDVDTENKIKENQEKLDEDLDKVN
                     LEKLHKNNVDNLVSKNGLEKTISILNKLKVASLRSLAGEYKDFGIKVSEISKADKNLL
                     IKKFKLYYEKN"
     gene            complement(5661..6329)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1558661..1559329"
     CDS             complement(5661..6329)
                     /gene=""
                     /locus_tag=""
                     /product="transcriptional regulator"
                     /translation="LKGCENMKKLICAKDVEELISKGEKIFYIDGTEIITPSARDLVK
                     NNGIEFTTKPCEIKVQSLENNKALNMDEFDSEMMINFFKKMMDKGILEEILKCLKQKS
                     LPFEAECDPSGLKVIRGNTVKMDVFDTGNPDAKVYFQELFSKKGSKIGAGFLTIEDSK
                     FHLKLNCEEMNYVIEGTLTVEINGKTYTAHAGDVLFLPKDSTVLLKSFAKTKVFYVKY
                     PESL"
     gene            complement(6924..7796)
                     /gene="eutJ"
                     /locus_tag="eutJ"
                     /db_xref="1559924..1560796"
     CDS             complement(6924..7796)
                     /gene="eutJ"
                     /locus_tag="eutJ"
                     /product="ethanolamine utilization protein eutJ"
                     /translation="LFSSRREGMSKGNLTFEYCDNMVQKFEEVIKKPILNESSVYYTG
                     VDLGTACVVLAVLDENYEPVAGAFRYADVVRDGMIVDYIGAVKIVRELKEEIEEKLNT
                     ELIYAAAAIPPGTDELDSGAIKNVVQAAGFELTRILDEPTAANALLKIENGAVVDIGG
                     GTTGISILKDGKVVYVVDEATGGTHFSLVISGAYGMSFKEADKFKRDSKNHKEILPIL
                     KPVIEKVSSIINNYIKNHDVCEISLVGGTCCLTGIEEIIEKQTKIYTHKPKNPMFVTP
                     LGIALSCTQDIIEE"
     gene            complement(7754..8422)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1560754..1561422"
     CDS             complement(7754..8422)
                     /gene=""
                     /locus_tag=""
                     /product="hypothetical protein"
                     /translation="MVKFITEECLRDLYKKEPFNTYRLQQGQRLTPGAAQYLSDKRIT
                     IKDGSKTTKEVEKEVKKVAENSNINLNKMVCLKLKSMEAAFLVTSSEILKEDIILAQN
                     IVNLGKKISNIRNVINKKAILEPIYLKECCKMNSLNFTTELDDCFEITEFHMQLKKSN
                     SILKIHTLRCAMRELQFEINKMYKSDDDSLKNRILDNVNLIINSLSQLICLAVGGKEC
                     QREI"
     gene            complement(8429..8872)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1561429..1561872"
     CDS             complement(8429..8872)
                     /gene=""
                     /locus_tag=""
                     /product="lysine-sensitive aspartokinase III"
                     /translation="MIKKRIMVIGSSGSGKTTIVNALNDYNGPLRRTPDLIYGKNTID
                     VPGAYIENPWMYKHIIALAQNSASCIVILVDQSNCTEVYPHGFAKSFRCPVIGVVTKC
                     DLMPENKEKCLGQLKDIGVVEPYFHISLKTGIDALKKYLLKKCKE"
     gene            complement(8869..9222)
                     /gene="eutS"
                     /locus_tag="eutS"
                     /db_xref="1561869..1562222"
     CDS             complement(8869..9222)
                     /gene="eutS"
                     /locus_tag="eutS"
                     /product="ethanolamine utilization protein eutS"
                     /translation="MGDFENRQIQRVIQESVPGKQITIAHVIASPMADIYERLGIDEC
                     GAIGILTLSPFETAIIAADIATKASDVEIGFLDRFTGSVVISGDVQSVETALNAVNNT
                     LKNMLGFTPALITRT"
     gene            complement(9262..10224)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1562262..1563224"
     CDS             complement(9262..10224)
                     /gene=""
                     /locus_tag=""
                     /product="benzylsuccinate synthase activating enzyme"
                     /translation="MKNMSNGNLGVIKEKATVFNIQKYSIYDGDGIRTLVFFQGCPLR
                     CKWCSNPEGLIKKHRVMFKSNLCVNCGACVSVCPVSIHTLSNETLKHEINRNIDCIGC
                     GKCKDACLKSAISIVGEEKTISELLKIVEEDRVFYEMSGGGVTLGGGEVLMQPKAASS
                     LLMACKQEGINTAIETCGYTNLETILKVAESVDLFLFDIKHINPDRHFELTGVRNEQI
                     LENLQELLRRKYNVKIRMPLLKDINNSKEEIEATMEFLTPYKDYKNFKGIDLLPYHKM
                     GVNKYNQLGIEYPIKGDPSLNDEELDRIEEWIKKYDLHVKVIRH"
     gene            complement(10237..12777)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1563237..1565777"
     CDS             complement(10237..12777)
                     /gene=""
                     /locus_tag=""
                     /product="formate acetyltransferase 2"
                     /translation="LDIREFSNMLMEATKNMSDEERNGLMNMFQSISKEIKKEEKVTS
                     NVVFNNNGEIPDGMTERLIKLKENYMKQVPSITTHRARAITKIAKENPGVPKSVLRGK
                     CFKYCCETAPLVIQDNELIVGAPNGKPRAGAFSPDIAWRWMEDEIDTIANRPQDPFYI
                     SEEDKKIMREELFPYWKGKSVDEYCEDQYREAGVWELSGESFVSDCSYHAVNGGGDSN
                     PGYDVILMKKGMLDIKREAEEKLASLSYERPEDIEKIYFYKSIIDTAEGVMIYAKRMS
                     DYAAELAAKETDPKRKAELQKISKVNARVPAHKPSTFWEAIQAVWTIESLLVVEENQT
                     GMSIGRVDQYMYPFYKSDIESGRMTDFEAFELAGCMLIKMSEMMWITSEGGSKFFAGY
                     QPFVNMCVGGVTREGRDATNELTYLLMDAVRHVKIYQPSLACRIHKGSPQKYLKKIVD
                     VIRAGMGFPACHFDDVHIKMMLAKGVSIEDARDYCLMGCVEPQKSGRLYQWTSTGYTQ
                     WPICIELVLNHGVPLWYGKQVCPDMGDLSQFKTYEQFEGAVREQIKYITKWTAVATTI
                     SQRVHRELAPKPLMSMMYEGCMEKGRGVEAGGAMYNFGPGVVWSGLATYTDSMAAIKK
                     LVFEEKKYTLEELSEALKADFVGYERLRKDCLEAPKYGNDDDYADYIAADLVNFTEQE
                     HRKYKTLYSVLSHGTLSISNNTPFGQMTGATANGRRAWMPLSDGISPSQGSDFKGPTS
                     IIKSVSKISCEDMNIGMVHNFKLMSGLLDTPEGEQGIIALLRSACALQLGEIQFNYLD
                     NETLIEAQKHPEQYRDLIVRVAGYSAFFVELCKDVQDEIISRTMLTHF"
     gene            13145..13534
                     /gene=""
                     /locus_tag=""
                     /db_xref="1566145..1566534"
     CDS             13145..13534
                     /gene=""
                     /locus_tag=""
                     /product="hypothetical protein"
                     /translation="LHIASAASSAKTKPKVSINPKALYLANVFYLPSIYKSISCTETI
                     SPTSLIGRGITLCAVNLPIAAAALAPASTDAFTAATSPFTIIVTRVEPIFSYEINSTL
                     AALSILSAASSAGTNPIVSTRPKASSP"
     gene            complement(13902..15017)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1566902..1568017"
     CDS             complement(13902..15017)
                     /gene=""
                     /locus_tag=""
                     /product="membrane spanning protein"
                     /translation="MSENSKTVSLEAIAAKKKLSSDFFKKGISLALFSGLAYGLYTAF
                     LTMGMTKGVWGDWYGDNTAGLSVFVIAYLLAALGNAINDTCSAIWSLLYAVVKGKFGD
                     FLRCINTKPGRIMILAALIGGPIASTAYVIALQMAGSIVVPISALCPAIAAILGKVLY
                     KQELNKRMAFGIVICVCASFLIGSTGFTSDGISRNTLLGLLIAIIAALGWGFEGCVAG
                     YGTAMIDPEIGICIRQVTAGIADLCILLPVLGMMAGGINISVDLTMQAFTSAPAMIWF
                     TLSGLLTFMTFMTWYAGNSMCGAGLGTACNGTYSFFGPLFCLLVLGVYGGMDGWALPT
                     VAWIGAVVMIIGILIISMNPLDLFKRKKMEVDVDETA"
     gene            complement(15461..16303)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1568461..1569303"
     CDS             complement(15461..16303)
                     /gene=""
                     /locus_tag=""
                     /product="transcriptional regulatory protein"
                     /translation="VVLNVKEELYSIGKVGEICKITKKALRYYDKMDILSPDKVSDES
                     GYRYYSKKTLLSVPMIKYYKQSGFKLEEMKVFLEGETYDFFHKSFRNKIDELKELEKE
                     INLKIRSVKDWDDLIVEAQNVIENNVCDVAIKYIDNKTLTFLDQEFKYDYMDSIINIE
                     FTNYIDSIENAITGPVIIRFPCHEDKMNGKCTKMRIMQETILKCKEELSVEFGGWMAA
                     ACYHIGPHETISDTYKKIKEWTKEHGYICFEECYERYVTDYWTTKNTDKFVTEILIKI
                     SRER"
     gene            complement(16374..17522)
                     /gene=""
                     /locus_tag=""
                     /db_xref="1569374..1570522"
     CDS             complement(16374..17522)
                     /gene=""
                     /locus_tag=""
                     /product="acetaldehyde dehydrogenase"
                     /translation="VYMKEFSINTDVYFGEGSLDRLNEIKNKRVLIVCDKFMETSGMV
                     TKVQQKLTDCEVTIYSDIVPDPSVEVIASGIQKLQSCNAQIIIALGGGSSIDGAKAIK
                     EYSKKVTGKTINIEEFYAIPTTSGTGSEVTEYAVITNKQEGLKYAITDKSLLPTVAIL
                     DPQLVKSVPKAITADTGMDVITHALEAYVSKNATDFSDALAEKAFTLAFRFLPQAYAD
                     GEDIIAREKLHNASCLAGMAFNAAGLGITHSLAHAVGGKLHISHGRSNAIILPYVVEY
                     NANLNKESFNAEYSIAAKKYQRLAKLLKLHAPNVTIGVNNLIKSIVKLQNTLMIPQTL
                     KQQREDINLDETSKEEIINAALRDVCTTSNPRETKKEDFLKILDKVLG"
ORIGIN      
        1 ttctcaatga ttattcaggt atatgtacta attattgtaa acttccattt catcattaat
       61 atatgcttcg caagaacgca tagctaaaat tgtttcttca aataatttat ttaactccca
      121 tccaagcatt tctgcacctt ttttaattac atctcgtgag catcccgctg caaatttctt
      181 atccttgaac tttttcttaa ggcttgaaat ttccatatcc ataacgctct tagatgggcg
      241 cattcttgcc gctgcaccaa taagacctgt aagttcatct actgcaaata atactttttc
      301 catctgatgc tccggtttag gaagttctcc ttggcaaagt ccatagccat gactagctgc
      361 tgcccttatt aatttttcat caagccctcg ctgtctcata atttcttgag tcttgatgca
      421 atgctcttct ggatagattt caaaatctaa atcatgaagt aacccaacca tagaccaaaa
      481 ttctacttca tcttcatatc ccaatttctc tgcaaaatat ttcatagttc cttcaactgt
      541 taaagcatgt tgaatatgaa atgcctcttt attgtattca ttaagtaaat cccacgcttc
      601 tttccttgtt atcataataa tatcctcctt taaaaatcac aaaatatgaa taaaaatgaa
      661 tctttactaa aatacttaag ttcactatac ttagatgcaa aacaaaattt ttctatttat
      721 tctcgttttt cttgtttcat ttaagcaatt actatataat agtttacgaa cgttaaatat
      781 atttaatgtt aactttattt tactttcgtt agttataatt gtcaatacca ttataggagg
      841 ttataccata atgaatataa attctattat tgcagaaaat cttaaaacac ttcgtactga
      901 aagaaattta agtttaggtc aacttgctga attatctggt atcagtaaag tcatgctatc
      961 tcaaattgaa aaaggtgaca ctaatcctac tataaatact ttatggaaaa tagctaaagg
     1021 attgaaagtg ccttatacat cattacttga gcaaaaaaaa catgatacat atgttataaa
     1081 gaaaagaaat attgaagctc aatttactga agaaggtcat tatcgagtat attgctacta
     1141 tactagtaca ccttatcgta attttgaact ttttcaaatt gaaattgatg agggttgttc
     1201 atataagtct ataggtcatt ctaaaaaatg ccaagaatat attatggttt tagaaggtga
     1261 attaacatta gaaataaaca ataaaattta taaactaact tctgatgatt caataagctt
     1321 ttctgcctct agtcagcata tatatattaa tagtggaaat gggactttaa aagctacaat
     1381 aacaaatttt tatcctgcct aataattagg caggatattt taatgatatc ttaatgggag
     1441 ctagtaaagc ttaaagtata atctcttcct tcatttctta ataaatattt acttcttaac
     1501 atccctaaaa aatctaaaaa aagttgatta ttactacttt tatcaacttc atctattatt
     1561 aaaactactt tttttctgaa aactcaacta aatatgattt agtcttttct ctaacaaata
     1621 taaagtagtg gttttcccat actgtcttgg tctatttata ataaaatatt cttcattatt
     1681 taccaatttt aatatactat ctagtttatt agatatatct accatatagt gtctttctgg
     1741 tatacaggtt tcagttacat taaatctctt tttcatataa ctttcactct ccttacccta
     1801 ttatattacc atagaataag atgtttaaac agaataatta tgggtttaaa agacatgtct
     1861 atggttttct taatgtagat ttaaatacat cctatgttaa ggttcaactt tcgacaaatt
     1921 gtgacaatta tagtattatt tctaatttaa atacatccta tgttaaggtt caaccactgt
     1981 aaaatcaagg tttcttaaaa ttaagaatac cataaacata ttgatatttc aaggtttcat
     2041 tgaaaattta ccaggtgatt ttaaaatttt ataaatcata taaaaaccta ccttaaactc
     2101 ttatatatca acgattaagc tagattctaa aattcttttc ggctggtaaa attcatatgt
     2161 taattatatc aataattcta tataatttaa aaggctctgc atatttaaat acttatttca
     2221 ttaaccatta tattttcaaa aataaaaacg tcactaaaaa attttagcga cgttttttac
     2281 tttacactat aattaaaata ttattttgca gtttctttag ctgatggaag aattacttca
     2341 acttcagaat gtggacgtgg tataacgtga actgacacta attctccaac acgttgtgca
     2401 gcagcagctc cagcatctgt agcagcctta acagctccaa catctcctct aaccataaca
     2461 gttacaagtc cgcctcctac atattcttta cctattaaat atacgtttgc tgccttaacc
     2521 atagcatctg ctgcctctat tgatcctacc aatccttttg tttctatcat tcctaatgca
     2581 tcatatttca ttttaaaatc ctcctattat cttttttatt tatttaaatt tttatttata
     2641 aacactattt tttatttctt attttacaat tgttaccttt gattttgatg taatacccat
     2701 tgcgttagct tcttcaatat caatatgaca ttcaagtttt gaggtattat tagctctaat
     2761 agctacatta ttatatattc cacctcttaa atcctcaaac tttattgata ctatttctcc
     2821 atcatgtact cctaaatatt tagcatcttc aggtgtcatg tgaatatgtc tttgggcaac
     2881 tattagccct tcctcaactt gaatagaacc ctttggtcca actattgtaa ttctagatgt
     2941 atcttttaaa tctccagata atcttacatg tggaactact ccaagtttaa tacaatctcc
     3001 agttaatact tccacttgag tcttacctct tacaggtcct agtattctaa ccttttctat
     3061 agcacctttt ggaccacaaa ttgtaacagt ttcattacaa gcatattgtc caggttgact
     3121 taaatcttta atttttacaa gttcataacc attaccaaat aaaatatcca aatctctttg
     3181 agaaagatgt atgtgtctat tggaaatacc tactggaatt tcagaagaat ttttattaac
     3241 ctcagtattt aatccttgtg atttaacagc ttctagtaaa agttttaata attcttcgca
     3301 attgtccatt agtttgcccc tttcatagca gcaactattt gattaaccaa gcttaaaagc
     3361 tcttcattat tagcgtcttt ttccttactt tcattactgc aaccagtatt tttagcataa
     3421 tcattacatt tatttaaaac ttctgcagca gcagcaattt gagcaggact catattcata
     3481 aattgattct taactccacg acaatttgaa gcagttttta tgcaattaaa agttgggtca
     3541 ttttgtacta aagttgcaca atcttttaat ccataagcaa ctcttttttt gtttataaga
     3601 tgttctgggg taacattttc agatactgaa cttcctcccc atgtaccaca tcctaaagta
     3661 aatgcaggtt taagacctgt gcttgcacct gttccacctt gagatcctcc tgtattaaca
     3721 agaatacgtg aagcaggttt ttttgcaaat tccataacaa tatcgtcatt ttgagtatgt
     3781 atactcattg tatgtccaat tccattttga agtaattcaa tacttaattc acaagcctca
     3841 tgccaatctt ttactgtata gaatgcaaga actgttgtaa gtttttcaaa ggatagtgga
     3901 ttaccattac ccacaccatt ttgctttcct ataagtactt taatatcttc tgaaactgta
     3961 aaccctgcag catttgcaat gacttgtgga cttcttccaa caaatttagc gttcatagta
     4021 tgtccatttt taaataacaa cttacaaact ttttcagttt cttctgctgt cataaaatat
     4081 ccaccttgtt ttttcaattc ttctacaact gcatcgtgat tacattcttc acaaattatt
     4141 gattgttctg aagcacaaat tgtaccataa tcaaaactct tacttgagat aatatctcta
     4201 atagcttttt ctacattagc agttctttca atgtatgcag gagagtttcc agcacctaca
     4261 ccaatagctg gttttcctga actataagct gctttaacca ttccaggtcc acctgtagct
     4321 attattaatg aaacattttc atttttcatt aattcatttg tagcttccat tgttaaatta
     4381 gttaaagaag ctataatatc ttctggagca cctgcttcta ttgctgcatc tctcattaat
     4441 tcaactgccc taattgtaca tttcgcagca gctggatgtg gagaaaacac aatagcatta
     4501 cgtgatttaa ttgcaattat ggatttaaaa attgcagtag atgttggatt agttgaaggc
     4561 actataccca taattaaacc aactggttcg gcaatttcta tcatcttatt taccttatct
     4621 tcactaatta cacctatagt tttcatatct ttaattgaat catataatat ggtagctgct
     4681 aaatgatttt tgtaagtttt atcttctact ttaccaaagc ctgtttcctc aactgccatt
     4741 tgtgctaaag atacagcatt ttcttctgca actcttacca tattacgtag aattttgtca
     4801 atttgttctt ctgtatagtt agcaatttta tttgccgcta cttttccaag tctagcaaga
     4861 tttcttgctt gttgtattga atacaaatcc ttatcatatt tttccattat atcttacttc
     4921 ctttcatgaa ctttaatcta gctaattttt ctcgtaatat aatttgaact ttttaattag
     4981 taaattttta tctgcctttg aaatttcgct aaccttaatt ccaaaatcct tatattctcc
     5041 agctaaactt ctaaggcttg caacttttag cttatttaat attgaaatag ttttttccaa
     5101 accattttta cttactaaat tatccacatt atttttatgt agcttttcta aatttacttt
     5161 gtctaaatct tcatctaatt tttcttgatt ttctttaatt ttattttcag tatctacatc
     5221 cttcaaattc tttgaatcat atatatcctc tacaatttgt tcttcttcta gagcctctgt
     5281 agtttctaca acttctgcct tttctacatt ctctacacta cttgtatctt cattagatga
     5341 tgaatcttct tgtaggttat tagatcctat tatgctttcc aattcctcat gaggtcgtgg
     5401 aattacatgt tctgaaacta aaaattcttc atttaagttt ttaacagctg cagcccctgc
     5461 ctctatagat gcttttactg cacctacatc acctgtaact gaaattgtaa caagaccgcc
     5521 acctacataa gttttttcaa taatacttac atctgctgat ttcaccatta catcagctgc
     5581 ctcaacagct gcaagtaatc cctttgtttc tattaaacca agagcttgca tggttaatcc
     5641 tcctaatttt ttataaaagt tctatagact ttctggatat tttacataaa acactttagt
     5701 ttttgcaaaa gattttaaaa gcactgtaga atcttttggt aaaaacaata catctccagc
     5761 atgggctgta tatgtttttc cattgatttc aactgttaaa gttccctcaa taacataatt
     5821 catttcttca caatttagtt tcaaatggaa ttttgagtct tctatagtta gaaaaccagc
     5881 accgattttt gacccttttt tactaaaaag ttcttgaaaa taaacctttg catctggatt
     5941 accagtgtca aacacatcca tttttactgt gtttcctcta ataactttaa gcccactagg
     6001 gtcacactca gcttcaaatg ggagactttt ttgctttaaa catttaagaa tttcttctaa
     6061 tatacctttg tccatcattt ttttaaagaa attaatcatc atttcactat caaattcatc
     6121 catatttaaa gctttattat tttctaaaga ttgtactttg atttcacaag gttttgtagt
     6181 aaattctatt ccattatttt ttacaagatc tctagctgat ggtgtaatta tttcagtgcc
     6241 atctatataa aatatttttt ctccctttga tattaattct tctacatctt tggcacagat
     6301 tagttttttc atgttttcac atcctttcaa ttaaaaagac tgtgttttaa cttaaattgc
     6361 aatcactatc aattattcca ataacaactg catctattgg aatattatca tcaccaagca
     6421 ttctgcgagc tccggatccg gtactaacaa taactctatc accaatacca gcaccgatag
     6481 tatcagcaac aataaatctg cgtcctttat atgttccact agcctcttct gctagcataa
     6541 atttaagtcc actaagggat tctgcttttc tagttgccca tacagtatct ataagttttg
     6601 ctagtatcat attgccccta cctctttcat ttttagtttg atctcattta atgcggcttc
     6661 aactgatgat gtatcaccca aaacacttat taaaaccata tgttgaggac aagttcctct
     6721 aatatcttca acggtaaccc ctacagcttt ttctgcaata tctgaagcat aaatcatatc
     6781 tataaattta ccttgaacaa gtcctattgc atcagcattt tccaaatctg ttatagagtt
     6841 tttgctcatt cgctttttta gaatatcttt agtgctattt gaaggtgatt ttataattct
     6901 aaaatccact tttaaacact ccccttattc ctctataata tcttgcgtac aacttaatgc
     6961 tattccaagt ggtgtaacga acataggatt tttaggtttg tgagtatata tttttgtctg
     7021 tttttcaata atttcttcaa ttcctgttaa acaacaggta ccacctacta aagaaatttc
     7081 acaaacatca tggttcttaa tataattatt aataattgat gatacttttt ctattactgg
     7141 ctttaatatt ggtaaaatct ccttgtggtt tttactatct cttttaaatt tatctgcttc
     7201 tttaaaggac attccatatg cacctgagat aactaatgaa aaatgtgtac cacctgtagc
     7261 ctcatccaca acataaacaa cttttccatc ttttaaaatt gatattccag ttgttcctcc
     7321 accaatatct acaactgcac cattttcaat tttaagtaga gcatttgcag cagtaggttc
     7381 atctaaaata cgtgttaatt caaatcccgc tgcttgaact acgtttttaa ttgctccaga
     7441 atctaactca tctgttccag gtggaattgc agcagctgca taaataagtt ctgtattaag
     7501 tttttcttct atttcctctt taagttctct tacaatcttt actgctccaa tatagtcaac
     7561 aatcatacca tcacgaacta catcagcata tctaaatgcg cctgcaactg gttcatagtt
     7621 ttcatctaaa acagctaata ccacacaagc agttcctaaa tccacacctg tatagtaaac
     7681 agatgattca ttaagaattg gtttttttat aacttcttca aacttttgaa ccatgttatc
     7741 acaatattca aaagttaaat ttccctttga cattccttcc ctcctactgc taaacaaatt
     7801 aactgagata atgaattaat tattaaatta acattatcta gaattctatt ttttaaactg
     7861 tcatcatcac ttttatacat cttgtttatt tcaaactgta gttccctcat agcacagcga
     7921 agtgtatgga tttttaaaat tgaattactt tttttaagtt gcatatgaaa ttctgttatt
     7981 tcaaaacaat catccagctc tgttgtgaaa tttaatgaat tcatcttgca acattctttt
     8041 aagtaaattg gctcaagtat tgctttttta tttataacat ttctgatatt tgatattttc
     8101 ttacctaaat ttacaatatt ttgtgctaag ataatatctt cttttaatat ttcactacta
     8161 gtaacaagaa atgctgcctc catagatttt aactttaaac ataccatctt atttaaattt
     8221 atattgctat tttccgctac ttttttcact tctttttcca cttcttttgt tgtttttgat
     8281 ccatccttta ttgttattct cttatcggat aaatactgag ctgccccggg ggtaagacgc
     8341 tgtccttgtt gtaacctata ggtattaaaa ggttcttttt tatataaatc tctcaaacac
     8401 tcttcagtaa taaatttcac cattgccctt tactccttac atttttttaa taaatatttt
     8461 ttcaaggcat caattcctgt tttaaggcta atatgaaaat atggttccac cacacctata
     8521 tcttttagtt ggcctaaaca tttttcctta ttttcaggca ttaagtcaca ttttgttaca
     8581 actccaatta ctgggcacct aaaggatttt gcaaatccat gggggtatac ttcagtacaa
     8641 ttagattggt caactaatat aactatacag gaggcactat tttgtgctaa tgcaattata
     8701 tgtttataca tccatggatt ttctatatag gcacctggaa catcaatggt gtttttacca
     8761 taaatcaaat ccggtgttcg ccttaatggg ccattataat catttaatgc atttactatt
     8821 gtggttttac cagaccctga tgaaccaatt accattatgc gtttttttat catgttcttg
     8881 taattaaagc tggagtaaat cctagcatat tctttagtgt attattaact gcattaagtg
     8941 ctgtttcaac actttgaaca tccccactta ttacaacaga acctgtaaaa cgatctaaaa
     9001 atccaatttc aacatcagaa gcttttgtag caatatctgc ggcaattatt gcagtttcaa
     9061 agggtgaaag agttaaaata cctatggctc cacactcatc aattccaaga cgttcatata
     9121 tatcagccat tggtgatgca ataacgtgag ctatagtaat ttgttttcct ggcaccgatt
     9181 cttgtataac acgttgtatt tgtctgtttt caaaatcccc cataaatcta accttccatc
     9241 ttattatcta tttaaaaatt atttaatgac ggattacttt tacatgtaaa tcatatttct
     9301 taatccattc ttctattcta tctaactctt catcatttaa gcttgggtca ccttttatag
     9361 gatattcaat tcccaattgg ttatatttat ttacccccat cttatgatat ggaagcaaat
     9421 caattccttt aaaattttta taatctttat atggtgttaa aaactccata gttgcctcta
     9481 tttcctcttt tgaattattt atatctttaa gtaaaggcat acgaatcttc acattatatt
     9541 ttctacgaag caattcttga agattttcta aaatctgttc atttcttact ccagttaatt
     9601 caaagtgtct atcgggatta atatgtttaa tatcaaataa aaataagtct acagattccg
     9661 caactttaag tattgtttcc aaatttgtat atccacaagt ttcaattgca gtatttatgc
     9721 cctcttgctt acatgccatt aataaactag aagctgcttt tggctgcatt aaaacttctc
     9781 caccacctaa tgtaactcca ccaccagaca tttcataaaa aactctatct tcttctacaa
     9841 tttttaaaag ttcagaaata gttttttctt ctccaactat tgatatggcg gatttgaggc
     9901 aagcatcttt acacttgccg catccaatac aatcaatgtt acgattaatt tcatgcttta
     9961 aagtttcatt agaaagtgtg tgtatggaaa caggacaaac agaaacacaa gccccacaat
    10021 taacacataa gttactttta aacataactc tatgtttttt aattaaccct tcaggatttg
    10081 aacaccattt acatcgaagg ggacaacctt gaaaaaatac taaagttctt attccatctc
    10141 cgtcataaat actatatttt tgtatattaa aaactgtggc tttttcttta attacaccta
    10201 aatttccatt actcatattc ttcattctcc agtttcatta aaaatgtgtt agcattgttc
    10261 tactgataat ttcatcttgt acatctttac ataattcaac aaagaatgca ctatatccag
    10321 caacacgaac aattaaatca cgatattgtt ctgggtgttt ttgtgcttct attaaagtct
    10381 cattatctaa atagttaaat tgaatctctc ctaattgaag ggcacatgca ctacgtaata
    10441 atgcaataat tccttgttca ccctctggtg tatcaagaag acctgacatt aacttaaagt
    10501 tatgaaccat acctatattc atgtcttcac aagatatttt tgaaacagat tttattatag
    10561 aagtaggacc tttaaagtca gatccttgtg atggacttat accatcagat aaaggcatcc
    10621 atgctctacg tccatttgct gtagctccag tcatttgtcc aaatggggta ttatttgata
    10681 ttgataaagt accatgacta agtactgaat ataatgtttt atatttacga tgttcttgtt
    10741 ctgtaaaatt aactaaatca gcagcaatat aatctgcata atcatcatca ttaccatact
    10801 taggtgcttc taagcaatct tttcttaatc tttcatatcc aacaaagtca gcttttagtg
    10861 cttcacttaa ttcttctaat gtatattttt tctcttcaaa tactagtttc tttatagctg
    10921 ccatggaatc tgtgtaagtt gcaagaccac tccatactac tccaggtcca aaattataca
    10981 tagctcctcc agcttctacc cctctaccct tttccataca accttcatac atcatagaca
    11041 taagtggttt tggtgcaagt tctctgtgaa cacgttgaga aattgttgta gcaacagctg
    11101 tccatttggt aatgtattta atttgttccc taacagctcc ttcaaattgt tcataagttt
    11161 taaactgact taaatccccc atatctgggc atacttgctt accataccat aatggtactc
    11221 catgattaag aacaagttct atacatatag gccattgagt gtatccagta gaagtccatt
    11281 gatataatct tcctgatttt tgtggttcaa cacatcccat taagcagtaa tctcttgcat
    11341 cttctataga aacaccttta gctaacatca tttttatatg aacatcatca aagtgacatg
    11401 ctgggaatcc catacctgca cggataacgt caactatctt tttaagatat ttttgaggtg
    11461 atcctttgtg tatacgacaa gctagagatg gttgatatat cttaacatga cgaactgcat
    11521 ccattaaaag gtatgttaat tcgtttgtag catctcgtcc ctctcttgta acaccaccta
    11581 cacacatatt tacaaatggt tgataacctg caaagaattt tgaaccgcct tcacttgtta
    11641 tccacatcat ttcagacatt tttataagca tacaaccagc cagttcaaag gcttcgaagt
    11701 cagtcatacg tcctgattca atgtcggatt tgtagaatgg atacatgtat tggtcaacac
    11761 gtcctataga catacctgtt tggttctctt caactacaag taatgactct atagtccaaa
    11821 ctgcttgtat agcttcccag aaggtacttg gtttgtgagc tggaactctg gcatttacct
    11881 tagaaatttt ttgaagttct gccttacgtt taggatcagt ttcctttgcc gcaagctctg
    11941 ctgcataatc tgacatacgt ttagcatata tcataacccc ttcagcagta tcaattattg
    12001 atttataaaa ataaattttt tctatatctt ctggtctctc atagctaaga cttgctaatt
    12061 tttcttctgc ttctcttttt atgtcgagca tacctttttt cattaggata acatcatatc
    12121 ctgggttaga gtctcctcca ccatttactg cgtggtatga acaatcagaa acaaaggatt
    12181 ctcctgaaag ttcccatact cctgcttcac gatactggtc ttcacagtat tcatctacag
    12241 attttccctt ccaatatggg aataattcct cacgcataat ttttttatct tcttctgaga
    12301 tgtagaatgg atcttgtgga cgatttgcta tggtatcaat ttcatcttcc atccatctcc
    12361 aagctatatc aggagaaaaa gctcctgcac gtggttttcc atttggtgct ccaactataa
    12421 gttcattatc ttgaattaca agtggtgcag tttcgcaaca atatttaaaa catttaccac
    12481 gtaaaactga tttaggcaca ccagggtttt ctttagctat tttagtaata gcccttgccc
    12541 tatgagttgt tattgatgga acttgtttca tatagttttc ctttaactta attagacgct
    12601 ctgtcattcc atctggaatt tcaccattat tattaaatac aacatttgat gtaacttttt
    12661 cttccttttt tatttccttg gaaatacttt gaaacatatt cattaaacca ttacgttctt
    12721 catcagacat atttttagta gcttccataa gcatatttga aaattcacga atatccaatt
    12781 tactccctca cattctttag tgtattttat atattaaatt aatataattt cttatttaaa
    12841 gccctacagg acttttttgg aatactctcc aatagtttat atttatctat gccattcaaa
    12901 ttaagtattt attttattat tctggtataa gagttgtaat agaatatcgt tttattattt
    12961 tttcaagttc ttcatgtgga cttgggataa caattgaact ataaaggttt ccaccttcca
    13021 ttccattaac tgctgcaaca cctgcatcta ctgctgacct acaagcacca acatctccac
    13081 taactaatac agatatataa cctgatgcca cattttcata tcctataagt tctacatttg
    13141 ccgctttgca catagcatct gctgcttcta gtgcaaaaac caaaccaaaa gtttcaatta
    13201 atcctaaagc tctatatctt gccaatgtat tctatctccc ttctatttat aaatcgatat
    13261 catgtactga aacaatatct cctacttctc taataggacg tggcataaca ttgtgtgctg
    13321 ttaatttacc aatagcagct gcggctttag cacctgcttc tactgatgct tttactgctg
    13381 caacatctcc ttttaccata atagttacaa gggttgaacc aatattttca tatgaaatta
    13441 attcaacatt agctgcctta agcattttat cagcagcctc aagtgctgga actaatccta
    13501 ttgtttctac aagacctaaa gcctcatcgc catagtatct catttttaat ttctccttcc
    13561 catcttaaaa ctcagtataa ttttttctac attataaatt ctattactta tagtctcttt
    13621 tatttttcta tgtgaattaa ttttaaaaat taatctggaa tatatttatt aattgtatct
    13681 gcaccttctt tgtgtgcatg ataataaact cttaattgct tgttttcatc taaatcaaat
    13741 cttacctctt caataagacc atttgcttct gctgtcatta aagcattggt tacggctttt
    13801 ctatttaaag ctttgaaatg tccgtattct ccttttaatg cttctataac atcatcaaca
    13861 caggcttctg gaacttttgt aaagtgtttt aaaattgcat aattaagcgg tttcatctac
    13921 atctacctcc atcttttttc ttttaaataa atcaagtgga ttcatagata ttataagaat
    13981 accaataatc attactacag ctccaatcca agcaacagta ggtaatgccc atccatccat
    14041 tccaccatat actcctaata ctaataagca aaatagtggt ccaaagaaag aatatgtacc
    14101 attacatgca gttccaagac ctgctccaca catactgttt ccagcatacc atgtcataaa
    14161 tgtcataaat gttaaaagtc cgcttaaagt aaaccaaatc attgcaggtg cacttgtaaa
    14221 tgcttgcata gtaaggtcaa ctgaaatgtt aattccacct gccatcattc ctaaaacagg
    14281 aagtaatata cataaatctg caattcctgc tgttacttga cgaatacaaa taccaatttc
    14341 aggatcaatc attgctgtac catatccagc tacacatcct tcaaatcccc atcctaaggc
    14401 tgcaataata gctattaata aacctaaaag ggtatttctt gaaataccat cagatgtaaa
    14461 acctgtacta ccaattaaaa aacttgcaca tacacatatt acaataccaa aagccatacg
    14521 tttgtttaat tcttgcttgt acaaaacttt acctagtata gctgcaattg cagggcaaag
    14581 tgctgatatt ggaacaacta tagaccctgc catttgaagt gctataacat aagctgtact
    14641 agctataggt cctccaataa gagctgcaag tatcataata cggcctggtt ttgtgttaat
    14701 acatcttaaa aagtctccaa attttccttt aactactgca tacaaaagtg accagatggc
    14761 actgcatgta tcatttatgg cgttgcctaa tgctgcaagc aaatatgcta taacaaatac
    14821 tgataagcct gctgtattat cgccatacca atctccccaa actcctttag tcatacccat
    14881 agttagaaat gctgtgtaca atccataggc aagacctgaa aataaagcta gggatatacc
    14941 ctttttgaag aaatcactgg ataatttctt ctttgcagca attgcttcta agcttactgt
    15001 ctttgaattt tcactcataa aaataagact cctttcagtt ataaattaat attaaatgta
    15061 tactaagatt gttataattt tgtacatttt acatttaagc tgtggaatac cttttcatcc
    15121 tttatcttgt aggttttatt ttcaattaga ttatattccc taccccatag ggtaaggtca
    15181 atatatattt cacaagaata ttcaaacaaa tttaaagttt ttacatttat aaagaaaaat
    15241 caccctttaa caagtgcttg aaaacactat gttagaggat gatttaaaat atcaattcca
    15301 tataacaact atggtattat ttgtataata atctacataa atttaatttt ctgaatagat
    15361 taaatacact ttttatttac tattattgtg ttttttttaa caaaaatgtg ttattagatc
    15421 tccttactct accctaaggg caaggtttta ctttataaca gttacctttc tctactaatt
    15481 ttaattaaaa tctctgttac aaacttatct gtatttttag tagtccaata atctgttaca
    15541 tatctttcgt agcattcttc aaaacatatg taaccatgtt cctttgtcca ctcttttatt
    15601 tttttatatg tatcgctaat tgtttcatga ggtcctatat gataacaggc agctgccatc
    15661 catccaccaa actccacact taactcctct ttacacttta aaattgtctc ttgcattatt
    15721 ctcattttag tgcattttcc attcatttta tcttcatgac atggaaaacg tataattaca
    15781 ggacctgtta ttgcattttc tatgctatct atataatttg taaattctat attaattata
    15841 gaatccatat agtcatattt aaattcctgg tctaaaaagg ttaatgtttt attatctata
    15901 tattttatag ccacatcaca cacgttgttt tcaattacat tttgtgcctc aactataagg
    15961 tcgtcccaat ctttaacgga tcttattttt agatttattt ccttttcaag ttcttttaat
    16021 tcatcaatct tatttctaaa gcttttatga aaaaagtcat aggtttctcc ttctaaaaaa
    16081 accttcattt cttcaagttt aaaaccactt tgtttgtaat attttatcat tggcaccgat
    16141 aataaagttt ttttactata atatctatat ccactttcat cagatacctt atcaggagat
    16201 agtatatcca ttttgtcata atatctcagt gctttttttg ttatcttaca tatctcccca
    16261 acctttccaa ttgagtataa ttcctctttc acattaagca ccacctatat tttaaaattt
    16321 tctgaaaagt attttgaaaa aaccaccctt taatgggtgg tttagaatac aatattatcc
    16381 taaaacctta tctagaattt ttagaaaatc ttctttttta gtttctctag gatttgatgt
    16441 tgtgcataca tccctaagag ctgcattaat aatttcttct tttgatgttt catccaaatt
    16501 tatatcctca cgttgttgtt ttaatgtttg gggaatcatc aatgtatttt gaagttttac
    16561 aatgctctta attaaattat taacaccaat agttacattt ggtgcatgta gctttaataa
    16621 tttagcaagc ctttgatatt ttttagctgc tatgctatat tctgcattga aagattcttt
    16681 gtttaaatta gcattgtatt caactacata cggaagtatt attgcattac ttcttccgtg
    16741 agagatatgt aattttccac ctacagcatg ggctaaacta tgggtaattc caagtccagc
    16801 tgcattaaat gccataccag caagacagga tgcattatga agtttttctc ttgctattat
    16861 atcctctcca tcagcatagg cttgtggtaa aaatctaaat gctaaagtaa aagctttttc
    16921 tgcaagggca tctgaaaaat ccgtagcatt ttttgaaacg taagcttcca aggcatgtgt
    16981 gattacatcc attcctgtat cagcagttat agctttaggt actgatttta ccaactgagg
    17041 atctagaatg gcaactgttg gaagaaggga tttatctgtg attgcatact ttaatccttc
    17101 ttgtttattt gtaattactg catattcagt tacttcagag cctgtaccac ttgtagtagg
    17161 tatagcataa aactcttcta tattgatagt ttttccagta actttttttg aatattcttt
    17221 tatagcttta gctccatcaa ttgatgaacc tccgccaagg gctattataa tctgtgcatt
    17281 acaactctgt aatttttgaa taccagatgc aataacttct acagatgggt caggaacaat
    17341 atcactgtat atggttactt cacagtcagt aagcttttgt tgtacttttg taaccatacc
    17401 tgaagtttcc ataaacttat cgcatacaat tagtactctt ttatttttaa tttcatttag
    17461 tctatctaaa gagccttctc caaaataaac atctgtatta atactaaatt ctttcatata
    17521 cacattctcc tattttaaaa gtattaagat atgaatgaat tagtaattct ttagcttaaa
    17581 tataaaatta acccacaatt 
//