LOCUS NC_002973:2 18825 bp DNA linear BCT 03-OCT-2011 DEFINITION Listeria monocytogenes str. 4b F2365, complete genome. ACCESSION NC_002973 SOURCE Listeria monocytogenes str. 4b F2365, complete genome. COMMENT locus start: 369650; locus end: 388474 FEATURES Location/Qualifiers source 1..18825 /organism="Listeria monocytogenes str. 4b F2365, complete genome." gene complement(0..1856) /gene="" /locus_tag="" /db_xref="369650..371506" CDS complement(0..1856) /gene="" /product="cell wall surface anchor family protein" /translation="MKLSKFFTIIALSATVTSSLPIPMVKAESTTANETKIENQLPKT DLKETPKEKTTNNNLKNQLVQAGTKTYNDYFPDDNLAKAVAEKMNKNVDESVTVEELA KITKLDARSQGIEDSTGIEYLTGLEILYLEDNQLKSIDVSKNLNLKDLACSNNPLANL DVSKNLALEELTCENNELTQLDVSKNTALEYLYCPRNQLTKLDVSKNSALRYLACDVN QLTSLDVSQNPALTNLGCTKNQLTDLDVSQNPNLSTLVCSDNQLTNLDVSQNQALAYL TCDNNGLKNIDIDQNLALIELSCENNQLTNLDTTQNLALEILYCDDNQLTNLDVRKNV NLLILSCNNNQLTNLAVGETILDVSCNNNQLKDISSLPDYLTAENGEYQAMDQTLVGP IQTTQNNTLVYAVPTDLLDKDGNIVSIIKPENGGVYDAATRTITWENLPDSGEVSYTF ESNDYGVFSGRVTVPYTGKETVSISSDDEISYKEGTTKTEEAFLTDIHASVTPATETI TSNFADVVDLQTPGKYVVKLSVAESDITKDVIVYVTEEPSKDNPVAPVPPKDPDNKVA DNDQNTEKPQVKVDEKTLPKTGDITSLSLSLAGIICLSFGILFFIKRKKKTV" gene 2367..2519 /gene="" /locus_tag="" /db_xref="372017..372169" CDS 2367..2519 /gene="" /product="hypothetical protein" /translation="LLIHSIITEDANNNEKEIDYEKQNKTDYHDWSGPFSITLRIPVN HHGGRK" gene 2503..5646 /gene="" /locus_tag="" /db_xref="372153..375296" CDS 2503..5646 /gene="" /product="cell wall surface anchor family protein" /translation="MAEENESKSVNTETTLEPKVALEEKTPQKPTLTNNLKQEKTVLQ AGETYETVFPDAALATVIAKAATGSEDITQEVSQTDLNKITSLTATSKGIVDLTGIDL LSKLTSLSISGNQITDISALNGLVNLSNLNVSNNKITSFNLNANSNLPMLSAVDIRSN NLKNINVQDQPKLWTFKCDTGSSSELTEVTLKNLPTLIVAGNGSSAYQNDIVFSSTPG LSKVILENLPSISSSVRLDRCAIEELVINNLPKVSMVNISNNKITTLEGLENLSAVNT LYVSENLVTEIESMHAFPKLQKLELGWNALTNVVMDQVTAEKFPLLRTMNVRGNNLIK INIQDQPKLWTFECDTGSSSELTEVTLKNLPILIAVGNGSSAYQDDIVFSSTPGLSKV ILENLPSTSSEVKLDHCAIEELVINNLPKVSVVIISYNKITTLEGLENLSAVSKIDAY ENLVTEIENLHAFPKLQTLTVDNNHISVLPTSLKTENPVLTTLSAMNQTITLKQKVIV SDLVLDNEVKNFGQITTAKSISNKGTYQNNQIKWLFEDIKSVNAVDYQFSEPVQEATI QGTFSGKVTQPIKASKVPVISADAEMNYPKNETVSEAAFFKDISASVTDDATLTSDFE SVVDFAKAGTYEVTLNAVNEDGVKAASVTVLVHIAKSPAPVITADKEITYTKNAEVSI TEYLAAIHAKTNDGSPIESDFATAVNWGTAGDYTVTLRSTNEDGVEAIPVEVTVHIAK SPAPVITADKEITYAKNAEVSITEFLAAIHAKTSDGSSIEADLDTAVTWGTAGDYTVT LRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEFLAAIHAKTSDG SPIESDFATAVIWSTAGDYTVTLKSTNEDGVEAIPVEVKVHIVEPLAPTISNVTFDVD DVQTTESLEAGELISEPLSPTKEGYTFIGWYDSKTGGNKWDFTTDKMPAYNIILYAQF SKDTNKAEAAGGDKPSTPSSIKVSPTGQSESGNLENRSNIKLPATGDDNATVLLVGFG LLMLGLFIRLTQKKRAK" gene 6036..11363 /gene="" /locus_tag="" /db_xref="375686..381013" CDS 6036..11363 /gene="" /product="cell wall surface anchor family protein" /translation="LKKKFSIVIISVLLLGYLAPFDTLLVGADETTVTEDTTVKTAET ETATEATESESGSDNEKAEEPKEAEASKETTEKEEKAKTKEPASNIKTEINTDKSQLK QTNLKAVVPAGSTYNSLFPDDNLAKKLAVIITGNAAATGNESVDSAALLAISQLDLSG ETGNDPTDISNIEGLQYLENLTSLNLSENNISDLAPIKDLVNLVSLNLSSNRTLVNLS GVEGLVNLQELNVSANKALEDISQVAALPVLKEISAQGCNIKTLELDNPAGAILPELE TFYLQENDLTDLTSLAKLPKLKNLYIKGNASLKSLATLKGATKLQLIDASNCTDLETL GDISGLSELEMIQLSGCSKLKEITSLKDLPNLVNITADSCAIEDLGTLNNLPKLQTLI LSDNKDLTNINAITDMPQLKTLALDGCGITSIGTLDNLPKLEKLDLKENQLTSISEIN DLPRLSYLDVSVNYLTTIGELKKLPLLEWLNVSSNRLSDVSTLTNFPSLNYINVSNNV IRTVGKMTELPSLKEFYAQNNNVSDISMIHDMPNLRKVDASNNLITNIGTFDNLPKLQ NLDVHSNRITNTSVIHDLPSLETFYAQNNLITNIGTMDNLPELTYVDLSFNRIPSLAP IGDLPKLEILKVTDNYSYLRSLGTMDGVSKLRNLELQNNYLNYTGTEGNLSALSDLTN LTELNLRDNGYISDISGLSTLSRLIYLNLDSNKIKDISALSNLTTLQELTLENNQIED ISALSDLDNLNKLALSKNKIIDISPAANMVNRGASVTASNQTYTLPTVLSYQSSFTID NPVVWYDGTPLAPSSIAHSGTYKDGEITWTNMTAASSSTEFNFNRLKDGLTFSGTITQ PYKSAVKVTANAEQTYTIGDTISEEQFLKDVNAKSSDGAPVTSDFATVVDLNTFGEYE VTLTSEKDGIQGDSCKVIVKVLHGAPVISADQTINYDKHATITEKQFLEDVHASTDLN TAITTNFSTAVNLNKGGDYTVALNSENEDGVKAETVYVTVTVDKDPAPIISAKTDITY DKFSKKTEAAFLDDIDADTNDGSIITSNFATAVNLDKAGDYTVTLNSINSDGVASTPT AIIVHVEKEKIATISANTAQQYEKYAEINETQFLKDVHASINASPTTAVLESDFETVV KLDVPGTYTVTITATNEDGGVSAPKEVSVIVKKLPAPEITADKEITYPKFDEVSEAEF LSDIHATINEKNVTITSNFSADVNLNKAGDYTVTLNATNEDGVKATPVEVIVHVQQGE RPVITADATISYDKFANITEAKFLEDIHATSSDGQSSTVITSNFETATNFKTAMSYTV TLNAVNEDGISAEPVAVTVTINKEPAATLKADAEVSYAKNEAVTESDFFKDVHLEGAE APSTAKATSNFDSVVDRSKTGDYTVTINATNEDGAVSTPIEVIVHIGAESAPVITANA EVKYNKHEQTDERRFLYDSDAKIDEANVEIKTDFAEKVDINKVGTYTVTLTATNEDGQ AANPVEVSVIVSDAAAEKVNVKYVDENGAEISAAETLTGNLDDAFSIDAKSIAGYKCD ATLSGVFSTVEQTVVFHYKAIEPGVVTIKYEDANGKAVAEDKQITGEVGDDFEAEAQT VSGYSCRAIASGKITEEPQTITFTYTTATPSKKSGEITVQYVDESGKKLADSKKVTGD IDDSYSVEAKAIDGYSVVGDDSAKGVFTEKSQTVTFKYKKNTQVSKDEPKVKGKTNQP PSADTKLKVDNNTLPATGDTENMALAVLIGFNMLLVASIFLFRKPKTNQ" gene 11587..12111 /gene="" /locus_tag="" /db_xref="381237..381761" CDS 11587..12111 /gene="" /product="hypothetical protein" /translation="MNKMIIYSSQYGTSKKYATELSQKKAIPMYSVESIPESIVEADE IIYVGAIYMGKVLGFDKFSKNYKTLSSKLIVISAGMYDPTRKENTDNIELTVKENLQK TNFLLKDIFCLKGRLDTQQLRLKHKMLVNALYKSAKRKKESDLNDNERDIVRAYEDDS QIDLNKLDGILDRV" gene 12324..12608 /gene="" /locus_tag="" /db_xref="381974..382258" CDS 12324..12608 /gene="" /product="hypothetical protein" /translation="MREIKVSEVTFQQHATKLASKSSGRYLPLKNGNMAYSRANSIDQ LRSALIDLVGVVEDFQHVTKQDAGRLKKMGIAYAKQDQVMGQKINQLEVR" gene 12609..12977 /gene="" /locus_tag="" /db_xref="382259..382627" CDS 12609..12977 /gene="" /product="hypothetical protein" /translation="LDSAHRQLEQQLQQIKKAKIMAETDVDQTRRKQNEQDWLEEDSH QLTQEKLVLLDFLRSGWQGEEASGFHRFLEEQQHEESQAWRRDLQDKRSDLDTELQEN KARLHTLETKQATLQKEWSK" gene 12974..14410 /gene="" /locus_tag="" /db_xref="382624..384060" CDS 12974..14410 /gene="" /product="hypothetical protein" /translation="VSRIDIAELNDFLHGLRSSNAEAKAMIRKIKEAAMDYAQDNRLK GEAVSTSKRYFSSTYTSICQSIIEALDESEERLAQYIREFGSQVDSSPSARIDAEILQ EAMAKVSQLQRKEEDLHRQLTAPNTKPDMQQVYAVKSRSVHTQLLKAIEKENILERYL AFEQSHGQFFSALDELIRATGRAVQELLHHVTFNDKTGTYSVPKSAVNSLLLMKKALD NARTENDQDPFPKAFEDYTVLAYTYVNDQGETVTMWLLEKDGKRVENKELQDFLEKHG QELDPLLYTNLSGEELERKVNDSWKEGINYLNGQKVSGFSGATLRSSAYVASMKDWTD DAGLTDMALGLGFGIAAARNKAIIPKESSGLKFDDIEKLENHFTKHGGEFKGAYSNIN EYLKGANNVIKNGEKVQYNYTLKDGTTELRTGYVKFMGNTSKGKAKFEFVGTNLSGDI TTYHVKRGEDVYKLLNGNKHINVINPIE" gene 14422..14817 /gene="" /locus_tag="" /db_xref="384072..384467" CDS 14422..14817 /gene="" /product="hypothetical protein" /translation="MRYEAKIISENPNIEEELKIKIKDIELLCFVEEYKCSVEVGQEY IVELETVVFDDLDIEKSTLQAKEITQVADSFAYFIRGVFHPSSKKIDSGIEIDLADED ISDFWYLENQFVALNVDRFNIDVIEKVNK" gene 14954..15073 /gene="" /locus_tag="" /db_xref="384604..384723" CDS 14954..15073 /gene="" /product="hypothetical protein" /translation="MDKVLDVGFFTTSGLLEGYEHLVGYYILGMILKQMNLGL" gene 15178..15408 /gene="" /locus_tag="" /db_xref="384828..385058" CDS 15178..15408 /gene="" /product="hypothetical protein" /translation="LKQCPVCENYTIEANYDICEVCYWEYDVVAQEYPDEIIGANNIS LKQAKINYAKFCAVEEKYITLVRKPRQDELPE" gene 15487..15714 /gene="" /locus_tag="" /db_xref="385137..385364" CDS 15487..15714 /gene="" /product="hypothetical protein" /translation="MEYEQMADSLAYGEEYNFYYKNEEYWLSKNREGHYLTKVSDGET QEFRTSEDLLGTARINGKLIIEIWENIQSQF" gene 15874..16143 /gene="" /locus_tag="" /db_xref="385524..385793" CDS 15874..16143 /gene="" /product="hypothetical protein" /translation="VKQLKKLTTEQSFEYYLSSLCMLGLHTINLSDEEIEYEIFEELA IDYPAALSPYTRELLVDNDIIDRGLSLLSKQLQTKLFELDGGILW" gene 16137..16259 /gene="" /locus_tag="" /db_xref="385787..385909" CDS 16137..16259 /gene="" /product="hypothetical protein" /translation="VVKALRTTPEWKEVLRLSDEIKGLIHQQWTDEELDYLLGK" gene 16519..16707 /gene="" /locus_tag="" /db_xref="386169..386357" CDS 16519..16707 /gene="" /product="hypothetical protein" /translation="MEERFEKIYTQGKLNIMEIWVDKETGVQYVYHLSGYAGGMSPLL DADGKPLLADLSKLNGAE" gene complement(16827..18824) /gene="tkt-1" /locus_tag="tkt-1" /db_xref="386477..388474" CDS complement(16827..18824) /gene="tkt-1" /product="transketolase" /translation="MSRIDEQMVNSIRVLSMDMIEKANSGHPGLPMGAAPMAFSLWKN HLKFNPEHPTWFNRDRFVLSAGHGSAMLYSLLHLFGYDLPMSELKNFRQTGSKTPGHP EFGHTVGVDATTGPLGQGFAMGVGMAMAEAHLGAKFNQPEFPVVDHNTYVLCGDGCLM EGISYEAASLAGHLKLGKLVVLYDSNDISLDGDLNESFSEDIELRFRAAGWQTLRVDD GNDLDALDAAIHLAKTEKSRPTLIEVKTVIGYGSPGKAGKSAAHGSPLGEKELKLAKE AYDWQMPPFELPKTVENQKEFYHSKGRASESSWLRTFNAYKQKYPALAESLQQLMDDN LDADWDAELPVFDENADKAVATREVSGIVLQELEKKLPNLFGGAADLASSNKTHLKAS ERFAPGNYAAKNISFGVREFAMGAAVNGMTLHGGVQAFGATFFVFSDYLRSAIRSAAL MGIPSTFIMTHDSIAVGEDGPTHEPIEHLASFRAMPGLHVIRPADGNETVEAYRYAFT QKEQPTMLVLSRQNLPILPNSAAKAQTGLAKGAYILADSPLDKLDIILLASGSEVHLM TAVRDNLAKKGFGARVVSMPSFDLFDKQSPEYKESVLPKAVKNRFAAEMGASYGWHKY LGDTGQILAIDSFGMSGPGDELARRFGFTVENLTELALKQL" ORIGIN 1 ttaaactgtt tttttctttc gtttgatgaa aaatagaata ccaaagctta agcaaataat 61 tccagccaat gacaaactta agctagtaat atcacctgtt tttggcaacg tcttttcgtc 121 tacttttact tggggttttt ccgtattttg gtcattgtct gctactttgt tatctggatc 181 ttttggtgga acaggagcga caggattatc tttacttggt tcctctgtca catacacaat 241 gacgtctttc gtaatatctg attctgccac gcttagtttt acaacatatt tacctggtgt 301 ttgtaagtct actacgtcag caaaattgct agtgatggtt tctgttgctg gagttacgct 361 tgcatggata tctgtgagga aggcttcctc tgtttttgta gtgccttctt tgtaactaat 421 ctcatcatca ctagaaatgc tgacagtttc ttttcctgta tatggcacag taactcttcc 481 agaaaacaca ccatagtcat tgctttcaaa tgtgtaactc acttctccgc tatctggtaa 541 attttcccac gtaatagttc tagtagctgc atcataaacc ccaccatttt ctggttttat 601 gatggaaaca atgttaccat ccttatctaa caggtctgta ggaacagcgt atacaagtgt 661 attattttgt gtcgtttgga ttggacctac taatgtttga tccattgctt ggtactcgcc 721 attctcagca gtaagataat ctggtaagga actaatatct tttagctggt tattattaca 781 gcttacatcc aatattgtct ctccaacagc tagattcgtt agttgattgt tattacaaga 841 taaaattaat aaatttacgt tttttctaac atctaaattc gttagctgat tgtcatcgca 901 atataaaatc tctaaagcta gattttgggt agtatctaaa ttcgttagtt gattgttttc 961 acaagataac tctattaaag ctagattttg atcaatatct atattcttca acccattgtt 1021 atcacaagtc aaatatgcta gagcttgatt ttggctaacg tctaagttgg ttaactggtt 1081 atcagaacaa accaaagtgc ttaaattcgg attttggcta acatctaaat ctgtaagttg 1141 gtttttagta caaccaagat ttgttaaagc tggattttga ctaacatcta aactggttaa 1201 ctgattgaca tcgcaagcca aataacgtaa agcggagttt ttactaacat ctagctttgt 1261 taactgattt ctagggcaat acaaatactc taaagctgta tttttgctaa catctagttg 1321 tgttaattca ttgttttcac aagtcaattc ttctaaagca agatttttac taacatctaa 1381 attcgctaac gggttgttag agcaagccaa gtcttttaga tttagatttt tactgacatc 1441 tatacttttt agttgattat cctcaagata aagtatctct aatccagtca aatattcgat 1501 tccagtgcta tcttctatgc cttggctccg tgcatctagt ttagttattt tagctaattc 1561 ctcgacagtt acagattcat ccacgttttt gttcattttt tctgctaccg ctttagctaa 1621 attatcatct ggaaagtaat cattataagt tttggttcct gcttggacaa gttgattttt 1681 caggttgtta ttcgttgttt tttctttcgg tgtttctttt aaatctgttt ttggtaattg 1741 attttcgatt ttagtttcat ttgcggttgt gctctctgct tttaccattg gtatcggtag 1801 gctacttgta acggtggcac ttaatgcaat tattgtaaaa aatttggaca gtttcatagt 1861 tagttgctcc ttcagttgct gttgtttagt atagtcagca gtgttcaaac aaaatatata 1921 ttagcacgtg aagatgagat tttatataga aactaccaga agatacaaaa tatcggctat 1981 tttgtgtcga aaatgttacg agttgcggtc gattataata ttggaacaat acttaagata 2041 ttaaattccc taacaatggc tactacgcct ttgtttcagc tgtttttatt ttaaaaacta 2101 ttctgtgaat ttgtctgttt atagtataaa tttaccgaag atagataaaa atccctcttg 2161 atactatatg aaaaagtaat aataatagta caaactcgtt gtgaatttga tatattatat 2221 ataaagcaac tccatctcct cataatttta cgcgaatttt agggctttaa cgaattagat 2281 gaaaaaagac taattgttat gtgtggagga gtttatggga tatatactta aataatactt 2341 ttcaatgaaa tagtaggtat ttttaacttg ctcattcatt ctattattac tgaagatgct 2401 aacaacaacg agaaggagat agattatgaa aagcaaaaca aaacagatta tcatgattgg 2461 agtggtcctt tttcaatcac tcttcgcata cccgttaatc accatggcgg aagaaaatga 2521 atcgaaatca gtaaatacag aaaccacgtt agagcctaaa gtagctctcg aagaaaaaac 2581 gcctcagaaa cctaccctta ccaataatct gaagcaagaa aaaactgtcc ttcaagcagg 2641 cgaaacatat gaaactgttt ttcctgatgc agctttagct actgtaattg caaaagcagc 2701 aactggttca gaggatatca cgcaagaagt atcgcaaaca gacttgaata aaatcacttc 2761 actaactgct acatctaaag ggatagttga tttaacagga atagatttac tttcaaaatt 2821 aacctcttta agtataagcg ggaaccaaat cactgatatt tctgcactca atggtctcgt 2881 gaatttgtcc aatctaaatg tatctaataa taaaataaca agtttcaacc taaacgcgaa 2941 tagtaattta cctatgttaa gcgctgttga tattcgtagt aataacttaa aaaatataaa 3001 tgttcaagac caacctaaat tatggacctt taagtgtgac acaggtagta gttcagagtt 3061 gacagaagtt acgctaaaaa atcttccaac tttaatagtt gcaggtaatg gctctagtgc 3121 ttatcaaaat gatattgttt tttctagtac accaggatta agtaaggtga ttctagaaaa 3181 tttaccatca ataagctctt cagtacgatt agatcgttgc gcgatagaag agttagtaat 3241 taataacctt ccaaaagtat caatggtaaa tataagtaac aacaaaatta ctacactaga 3301 aggacttgaa aatttatctg cagtaaacac tttatacgta tctgagaatt tagtgactga 3361 aatagaaagt atgcatgcct tccctaaatt acagaagtta gagctgggat ggaatgcact 3421 tactaatgtg gtaatggatc aagtaacagc ggaaaaattc ccgttattaa gaacaatgaa 3481 tgttcgtggt aataatttaa ttaagataaa tattcaagac cagccaaaat tatggacctt 3541 tgagtgcgac acaggtagta gttcagagtt gacagaagtt acgctaaaaa atcttccaat 3601 tttgatagct gtaggtaatg gctctagcgc ttatcaagat gatattgttt tttcgagtac 3661 accaggatta agtaaggtga ttttagaaaa tttaccatca accagctctg aggtaaagtt 3721 agatcattgc gcgatagaag agttagtaat taataacctg ccaaaagtat cagtggtaat 3781 tataagttac aacaaaatta ctacactaga aggacttgaa aatttatccg cagtaagcaa 3841 aattgacgcg tacgagaatt tagtgactga aatagagaac ctacatgcgt tccctaaatt 3901 acagacactc accgtagaca ataaccatat cagtgtattg ccaacaagtt tgaaaacgga 3961 aaatcccgta ttaacaacgc taagtgcgat gaatcaaaca atcactctaa agcaaaaagt 4021 tatcgtgtca gacctagttc ttgataatga agtgaagaat ttcggtcaaa taaccactgc 4081 caaatccatc tctaataagg gaacctatca aaataaccaa atcaagtggc tttttgaaga 4141 tataaaaagc gtgaatgccg ttgattatca atttagtgaa cctgttcaag aggcaactat 4201 tcaaggaact ttttcgggga aagtgacaca accaatcaaa gcatctaaag taccagttat 4261 tagcgcagat gcagagatga attacccgaa aaacgaaacg gtatcagaag ctgccttttt 4321 caaagatatt tctgcaagcg taacggatga tgcaacacta acttctgatt ttgaaagtgt 4381 tgtggacttt gcaaaagcgg gaacgtatga agtgacatta aatgcagtga atgaggatgg 4441 agtaaaagcg gcttcggtga ctgtattagt gcatatcgct aagtcgccag cgccagtaat 4501 taccgcagat aaagaaatca catacactaa aaacgcggaa gtcagcatca cggaatatct 4561 tgcagcgatt catgctaaaa cgaatgatgg ttcaccaatt gaaagtgatt tcgctacggc 4621 tgtaaattgg ggcactgcag gagattatac cgtaacgcta aggtctacaa atgaagatgg 4681 agttgaagca atccctgtag aagtaactgt gcacatcgcc aagtcgccag cgccagtaat 4741 taccgcagat aaagaaatta cgtacgctaa aaacgcggaa gtcagcatca cggaatttct 4801 tgcagcgatt catgctaaaa cgagtgatgg ttcatcaatt gaagctgatt tagatacggc 4861 tgtaacatgg ggcactgcag gagattatac cgtaacgcta aggtctacaa atgaagatgg 4921 agttgaagca atccctgtag aagtaactgt gcacatcgcc aagtcgccag cgccagtaat 4981 taccgcagat aaagaaatta cgtacgctaa aaacgcggaa gtcagcatca cggaatttct 5041 tgcagcgatt catgctaaaa cgagtgatgg ttcaccaatt gaaagtgatt tcgctacggc 5101 tgtaatatgg agcactgcag gagattatac cgtaacgtta aaatctacaa atgaagatgg 5161 agtagaagca atccctgtag aagtaaaggt gcatatcgta gagccactag caccaacgat 5221 ttcgaatgtg acatttgatg tggatgatgt acaaacgaca gaatctcttg aagctggaga 5281 gctaatttct gaaccattga gcccaacaaa agaaggctat acttttattg gttggtatga 5341 ctcgaaaact ggtggtaata aatgggattt tacaacagat aaaatgccag catataatat 5401 tattctttat gctcagttta gtaaagatac aaataaagca gaagcggccg gtggagataa 5461 gccctcaaca ccctcttcta taaaagtaag tccaacaggt cagtccgaga gtggaaactt 5521 ggaaaataga tctaatatta aattaccagc tacaggcgat gataatgcaa ctgttttatt 5581 agtgggcttt ggattactaa tgttggggct tttcattcgc cttactcaaa aaaagcgtgc 5641 taaataaaag ctcatagaaa tttaaaaaat agtgtaattg gttgcttcta ggagataaat 5701 agttgcaact cacaaggaga ggagacagag agctgtctcc tctttttttg atactggagt 5761 actaaaagat agcagaaaaa acgagtaaca tgtcccaaaa caacttttaa ctttatgaaa 5821 aggggtgata gtttttttgc ctattattcc ctcaaagacg aaggatagtc taataataga 5881 acttcctctg cgatttaata agtgaaaccc aaaaatagac acattttccg gacgatttag 5941 tactgactcg aactatctaa ctatttctaa catcttataa ttaattagtg tcaattttat 6001 tcaaaataaa ttaaaagata gaatagaggg aaagtcttga aaaagaaatt tagtatagtt 6061 attatcagcg tattgttact tggttattta gcgccttttg atactctatt agtaggtgca 6121 gatgaaacca ctgtcaccga agatacgaca gtgaaaacgg cagaaacaga aactgctact 6181 gaagctacag aaagcgaatc tggttcagac aatgaaaagg cagaagagcc aaaagaagca 6241 gaagcaagca aagaaacgac agaaaaagag gaaaaagcga aaacaaaaga accggcttct 6301 aatattaaaa cagaaattaa tacagacaaa agtcagttga aacaaactaa tttaaaagca 6361 gtagtaccag caggaagcac atataattct ttgtttccag acgacaatct tgctaaaaaa 6421 ttagccgtga ttatcacagg aaatgcggct gcaacaggta atgaatcagt ggatagtgca 6481 gctcttttag caataagcca acttgatttg agtggggaaa cgggcaatga cccaacggat 6541 atttccaata ttgaaggatt acaatattta gagaatttaa cgagcctgaa tttaagtgag 6601 aataatatat ctgacttggc cccaattaaa gatttggtga acctggtttc acttaacctt 6661 tcttccaatc gaacattagt aaatctttca ggggtggagg gtttagttaa tttgcaagaa 6721 cttaatgtct ctgcaaataa ggcgttagaa gatatttcac aagttgcagc attaccagtg 6781 ttaaaagaaa ttagtgcgca aggctgtaat attaaaacat tggaattaga taatccagct 6841 ggcgctattt tgccagaact agaaacattt tacttgcaag aaaatgattt aaccgactta 6901 acttcattag caaaacttcc aaaactaaag aatctctata ttaaagggaa tgcttcttta 6961 aaaagtttag cgacattaaa aggggcgacg aagcttcaat tgattgatgc gagtaactgt 7021 accgatttag aaacgcttgg agatattagc gggctttcgg aactcgaaat gattcaatta 7081 agtggttgta gtaaactgaa agaaatcaca agcttgaagg acttgcctaa tttggtgaat 7141 attacggcag atagctgtgc gattgaagat ttaggaacac tgaataattt accgaaatta 7201 cagacattaa ttctctcaga taataaagat ttaaccaata ttaatgcaat taccgatatg 7261 ccacaattaa aaacattagc cttggatggc tgcggaatta catctattgg aacgcttgat 7321 aaccttccta aattagaaaa attagatctc aaggaaaatc aactaactag tataagtgaa 7381 ataaacgact tacctcgatt aagctattta gatgtaagtg taaattatct tacaacaata 7441 ggggaattaa aaaaattacc actattagaa tggttgaatg ttagttcgaa taggttatca 7501 gatgtgagta cactaacaaa tttcccgagt ttaaattata ttaatgtatc aaataatgtc 7561 attaggacag tcggtaaaat gactgaatta ccttcactga aggaatttta cgctcaaaac 7621 aacaatgtat cagatatttc gatgattcac gatatgccga atttaagaaa agtggatgcg 7681 agtaataact taattacaaa tataggtacc tttgataatt taccaaaatt gcaaaaccta 7741 gatgtgcatt caaatagaat tacaaataca tccgttatac atgatttacc aagtttggag 7801 acgttttatg cgcaaaataa tttgattacc aatattggta cgatggataa tttaccagaa 7861 ttaacttatg tagatttatc tttcaacaga ataccatcac ttgctccaat tggcgactta 7921 cccaagttag aaatattaaa agttacagac aattattctt atttaagaag cctaggaacg 7981 atggacggtg tttctaagct gagaaattta gaattacaaa acaattacct taattacact 8041 ggaacagaag ggaacttaag tgcattaagt gatctaacaa atctaacgga attaaatttg 8101 cgagataatg gttatattag tgatataagt gggctttcca ccctatcaag actaatctac 8161 ttaaatttag attccaataa aattaaagat atttctgcct tatctaattt gacgactctt 8221 caagaattaa cacttgaaaa caaccagatt gaagatattt cagcacttag tgatctggat 8281 aatttaaaca agctagctct atcaaaaaat aaaattattg atattagtcc tgccgctaat 8341 atggttaatc ggggggcgag tgttactgcg agtaatcaaa catatacatt gccaactgta 8401 ttatcatatc aaagctcatt taccatagat aatccggttg tttggtatga cggcacacca 8461 ctagcgccat catctatagc gcactctggt acttacaagg atggggaaat aacttggact 8521 aacatgaccg cagcctccag ttccactgaa tttaacttta ataggctaaa agatggttta 8581 accttctcag gaacaatcac ccaaccttat aaatctgcag ttaaagtaac tgcaaatgca 8641 gagcaaactt atacaattgg tgatactatt tcagaggagc agtttttaaa agatgttaat 8701 gcaaaatcat cggacggggc tcctgttaca agtgattttg ctacagtggt ggatttaaac 8761 acttttggtg aatatgaagt tactctaact tctgaaaaag atggaatcca aggggatagt 8821 tgcaaagtaa ttgtcaaagt tcttcacgga gcgcctgtca tttcggcaga ccaaacaatt 8881 aattatgata aacatgcgac tattacagag aaacaatttt tagaagatgt tcatgcgagt 8941 acggatttaa atacagctat tacaactaat tttagtacag cagttaactt gaataaaggc 9001 ggagattata ccgttgcgct aaattctgaa aatgaggacg gcgtgaaagc tgaaacggtc 9061 tatgtcactg ttactgtaga caaagatccg gcgccgatta taagtgcgaa aactgacatc 9121 acttatgaca aattctctaa aaaaaccgaa gcagctttct tagatgatat agacgcagat 9181 acaaatgatg gctctataat aacttctaac tttgctacag cagttaattt agataaagca 9241 ggtgattata ctgttactct gaattctatt aatagtgatg gtgtagcgtc tacgccaact 9301 gcaattattg tccatgtgga gaaagagaaa atagcaacga ttagcgcaaa tacggcacaa 9361 caatatgaaa aatatgcgga gattaatgaa acgcaatttc taaaagatgt tcatgctagt 9421 attaacgcga gcccaacaac cgcagttttg gaaagtgatt ttgaaacagt agttaaacta 9481 gacgtcccag gaacgtacac agtaacgatt actgctacaa atgaagatgg cggagtatcg 9541 gcaccaaaag aagtttctgt catagtaaaa aaacttccag cgccagaaat cactgctgat 9601 aaggaaataa cctatccgaa atttgatgaa gtaagtgaag cagaattttt aagtgatatt 9661 catgcaacta ttaatgaaaa aaatgtaacg attacaagta acttcagtgc cgatgtgaat 9721 ttaaataaag ctggcgatta cacggtaaca ttaaatgcta cgaatgaaga cggcgtaaag 9781 gctacaccgg ttgaagtaat tgtacatgtt caacaaggag aacgtcctgt tataacagcc 9841 gatgcaacta tttcctatga caagttcgct aacataacgg aagcgaagtt cttagaagat 9901 attcatgcaa caagtagtga tggtcaaagc tcaactgtaa tcacctctaa tttcgagacc 9961 gcgacaaact tcaaaacagc catgagctac acagttacgc ttaatgctgt aaatgaagac 10021 ggcattagcg cagaaccagt agcagtgacc gttacaataa ataaagaacc agccgcgacg 10081 ttaaaagctg atgcagaagt aagctatgcg aaaaatgaag ctgtaaccga atctgatttc 10141 ttcaaagatg ttcatttaga aggagcggaa gccccaagta cagcaaaagc aacaagtaat 10201 tttgattccg tagtagatag aagtaaaaca ggagattata ctgttacgat aaatgctaca 10261 aacgaagatg gggctgtctc tacaccaatt gaagtaattg ttcacattgg agcagaaagt 10321 gcaccagtaa ttacagcgaa tgcagaagta aaatataaca aacatgaaca aacagatgaa 10381 agaagatttt tatatgatag tgatgcaaaa atcgatgaag ctaacgtgga aattaaaacc 10441 gattttgcag aaaaagtaga tattaataaa gttggaactt atacggtcac actgactgct 10501 acgaatgaag atggccaagc tgccaatcca gtagaagtaa gcgtcattgt aagtgatgct 10561 gctgctgaaa aagtaaatgt gaaatatgta gatgaaaatg gagcagaaat tagtgcagcg 10621 gagaccttaa ctggtaatct agatgatgca ttttctattg acgcgaaatc tatagctgga 10681 tacaaatgtg atgccacttt aagcggcgta ttttcaacag ttgagcagac agttgtgttt 10741 cattataaag caatcgagcc tggtgttgta acgattaaat acgaagatgc aaatggaaaa 10801 gcagttgccg aagataaaca aataactggc gaagtaggag atgattttga agctgaggcg 10861 caaacggtga gtggttattc atgccgagca attgcaagtg gtaagataac agaagaaccg 10921 caaactatta ctttcacata cactacagca acgccttcca aaaaatcagg cgaaataaca 10981 gttcagtatg tagatgagtc aggtaagaaa ttggctgatt ctaaaaaggt tacaggggat 11041 attgatgata gttatagtgt agaagccaag gcaattgatg gctatagcgt agttggcgat 11101 gattctgcta aaggtgtttt taccgaaaaa tcgcaaacag ttacttttaa atacaagaaa 11161 aatacacaag ttagtaaaga tgagcctaaa gttaaaggga aaacaaacca accaccaagt 11221 gctgatacga agctaaaagt agacaataat acgttgcctg ccaccggaga tactgaaaat 11281 atggcattag cagttttaat cggttttaat atgctactcg ttgctagtat attccttttt 11341 agaaaaccaa aaacgaacca ataaatggat aatctttaaa taatagaagc cttatagaat 11401 tcattaaata atgatatttt ataaggcttt tattacttat tgaaccaaat ctaacaggaa 11461 gtaatgatga aaagcttcct tctaatttct aatgtgaact ataaaacgtt catgaaatgc 11521 acacaaacaa tttgtttttg aatgttataa taatatggaa gcttataaag aagggagcag 11581 gaagatgatg aataaaatga ttatttattc aagtcaatac ggcaccagta agaaatatgc 11641 aacagagctt agtcagaaga aagctattcc aatgtattct gtggaatcta ttcctgaatc 11701 aatcgttgaa gccgatgaaa tcatttatgt tggtgcgatc tatatgggaa aagtactcgg 11761 atttgataag ttttctaaaa attataaaac tttgtcaagt aaattaatcg ttatttcagc 11821 tggaatgtat gatccaacac gcaaggaaaa tacggataac atcgaattaa cggtcaaaga 11881 aaaccttcaa aaaactaatt ttttattaaa agacatattt tgtttaaaag ggagactaga 11941 tacacagcaa ctccgcttga aacataaaat gttagtcaat gctttatata agagtgcaaa 12001 aagaaaaaaa gagagtgact taaatgataa tgaaagagat atagtgcgtg cttatgaaga 12061 cgattcgcag attgatttga ataagttaga tggtatttta gatagagtgt agctgacaac 12121 caaaagaaaa tagcccaaaa gcctgtcttt aaagagaggc tttttggtat tgacttagtt 12181 agaagatgaa atgttaattt tttcacttaa aaagctgatt ttaagctgtt tttcaatgaa 12241 ttgtttcaca gaatgctcac aaaagaggtg tgctaccggt gctataatga gggggaagga 12301 tttacataga gaggaagcat gcagatgaga gaaataaaag ttagcgaagt aaccttccaa 12361 caacacgcaa ccaaattggc aagtaaaagt tcgggaagat acttaccatt aaaaaacggg 12421 aacatggctt attccagagc caattcaatt gatcaattgc ggtcggcatt gattgatttg 12481 gtaggcgtag tggaggattt tcaacacgtg accaagcaag atgcgggccg attaaagaaa 12541 atgggtattg cctatgccaa gcaagaccag gtcatgggac aaaaaatcaa tcagttggag 12601 gtgcgttaat tggatagcgc acaccgccaa ctagaacaac aactccaaca aattaaaaaa 12661 gcgaaaataa tggcagaaac ggatgtcgat caaacgagaa gaaaacaaaa tgaacaagat 12721 tggttagaag aggacagcca ccaattaaca caagaaaaac tggtgttatt agacttttta 12781 cgcagtggct ggcaaggtga agaagccagt ggttttcatc gttttttaga agagcagcaa 12841 cacgaagaat ctcaggcttg gaggcgtgat cttcaggata aaagaagcga tttagacacg 12901 gaattacaag aaaataaggc caggctccac acgttagaaa ccaaacaagc caccttacaa 12961 aaggagtgga gcaagtgagc cggatagata ttgcggaatt gaatgacttt ctccacggtt 13021 tgcgaagtag taatgcggaa gccaaagcga tgattagaaa aattaaagaa gcagcgatgg 13081 attacgccca ggacaatcgt ttaaaagggg aagcagttag tacctccaaa cggtattttt 13141 ctagtaccta tacaagtatt tgccagagca tcattgaggc actggatgaa agcgaagagc 13201 gactagcgca atatattcgc gagttcggga gccaagtgga tagttcgcct tctgccagaa 13261 ttgatgcaga aatcttacaa gaagcgatgg ccaaggttag ccagttacag cgaaaagaag 13321 aagacttgca tcgacaattg acggcgccga acacgaagcc ggatatgcaa caagtctatg 13381 cagtgaaatc aagaagtgtt catacacaat tattgaaggc aatcgaaaaa gagaacatcc 13441 tagaaagata tttagctttt gaacaaagtc atggccagtt ttttagtgcg ttagacgaac 13501 tcattcgagc aaccggacgt gcggtgcaag aattgctaca tcatgtgact tttaacgata 13561 aaacagggac ttattccgtg ccgaaaagtg cggtaaacag cttgttgctt atgaaaaaag 13621 cgctggataa cgcacgaaca gaaaatgacc aagacccctt tccgaaagct tttgaagatt 13681 acaccgtgtt agcttatact tatgtcaatg atcaaggcga aaccgtgacg atgtggttac 13741 ttgaaaaaga tggaaaacga gtagaaaaca aggaattaca agatttctta gaaaaacatg 13801 gtcaggaatt agacccactt ctttatacca acctttctgg agaagaactc gaacgaaaag 13861 tgaatgattc ttggaaagag ggtatcaact atttaaatgg tcaaaaagta tctggatttt 13921 ctggagccac actgcggtca tccgcttatg tggctagtat gaaagattgg acagatgatg 13981 ctgggttgac agatatggca ttaggtttag ggtttgggat tgcagcagct agaaataaag 14041 cgataatacc taaggaatcc agtggactta aatttgacga tatagaaaaa ttggaaaacc 14101 attttacaaa acatggaggg gagtttaaag gtgcatattc gaatataaat gaatatctaa 14161 aaggggcgaa taatgtaatt aagaatggtg aaaaagtaca atataattat acattgaagg 14221 atggaacaac cgagttgaga actggctatg tgaagtttat ggggaacact agtaaaggaa 14281 aagcaaaatt tgaatttgtt ggtactaact tatctggaga tattacgacc taccatgtga 14341 aacgcggcga ggatgtatat aaattattga atggaaacaa gcatataaat gtgataaatc 14401 caatagaata ggagaataat aaatgagata tgaagcaaaa ataatttcag aaaatcctaa 14461 tattgaagaa gagttgaaaa ttaaaataaa agatattgaa cttttatgtt ttgttgaaga 14521 atacaaatgt tcagtagagg ttggccaaga atatattgtt gagttagaga cggtcgtttt 14581 cgatgattta gatattgaga aaagtacttt acaagctaag gaaataactc aagtagcaga 14641 tagttttgca tactttatca gaggcgtttt tcatccttct agtaagaaaa tagattcagg 14701 gatagagatt gatttagcag atgaggatat ttctgatttt tggtatttgg aaaatcaatt 14761 tgttgcatta aatgttgata gattcaatat agatgttata gaaaaagtaa ataagtaaaa 14821 aacactccac atctcaatta gcgtcgtaaa agtagatcct tgataacctt attttttaga 14881 aagtacggaa tagaaaaatg aaatgatttg agcactttaa caaatttaat tatgagcttt 14941 ttggaaaaat attaatggat aaggtattgg atgtagggtt tttcacaaca agtggattat 15001 tggaaggtta tgaacattta gtagggtatt atattttagg tatgattcta aaacaaatga 15061 atttgggatt ataaacgagt atggatctat atctacatat ttcaaaccta atgctggatt 15121 aaaatattgg gagaaacaaa ttgatttata ttatccgaaa tgatgaggag gaataacttt 15181 gaaacagtgt ccagtttgtg aaaattatac gattgaagct aattacgata tttgcgaagt 15241 atgctactgg gaatatgatg tggtagctca agagtatccg gatgaaatta taggagctaa 15301 taatatttcg ttaaaacaag caaaaataaa ttatgcgaaa ttctgcgcag tagaggaaaa 15361 atatattaca cttgttcgaa aaccgagaca ggatgaacta ccggagtgat tgaacggata 15421 gagggagttt aaagtaatgt gcttttttaa taaatagaga acctgtttct gaaagaagga 15481 aagaagcatg gaatatgaac aaatggctga tagtttagca tatggtgagg aatataattt 15541 ttactacaaa aatgaggaat attggttaag taaaaatcgg gaaggacatt acttaacgaa 15601 agtatccgat ggagaaacac aagaatttag gacttcagaa gacttattag gaacagctag 15661 aataaatgga aaacttataa tagaaatttg ggaaaatata caaagtcaat tctaaattga 15721 agaaatagag accttcattt tcaagtgttt tatagttgtt atagcttttt tgttagaaat 15781 gctaagaaag aacatacgag attacatagt tgacgattca taatacacgc acaccacaca 15841 aatccattga ctataatatt aaaaaataaa tgaggtgaaa caattgaaaa aattaacaac 15901 agaacagtct tttgaatatt acctttcttc gctatgtatg ttaggattgc atacaattaa 15961 tttatccgac gaagaaattg aatatgaaat atttgaagag ttagcaattg attatccagc 16021 tgctttgagt ccatatacta gggaattgtt ggtggataat gacataattg atagagggct 16081 ttctttacta agcaagcagc tgcaaactaa actttttgaa cttgatggag gaattctgtg 16141 gtaaaagcat tgagaacaac gccagaatgg aaagaggttt tacgattatc tgatgagata 16201 aagggattga ttcatcaaca atggacagat gaagagctag attatttatt ggggaaatag 16261 tttcttagtc tatggaatta ggtgtaaatt ctatgtgctc tttgaaaaag gaattgccta 16321 caattaagtg aatgccagaa attgttgata ttaaaaattt aaatttatag aagtaggctt 16381 taagttggtt aaaacaggat actttaaata gaggaaatta gagagaaagt acattttatt 16441 gagcaatatt ttgattcgga aattaaattg atttagggtg gaataatgcg tgcaacctta 16501 aaacaggagg cggaaaacaa tggaagaaag atttgaaaaa atttataccc aaggaaaact 16561 caacattatg gaaatttggg ttgataaaga aaccggtgtg caatatgttt accatttgtc 16621 tggttatgcg ggtggaatgt caccactttt ggatgcagat gggaaaccgc tacttgctga 16681 tttatctaag cttaatggcg ctgagtaaag tgggaaattg atttctagtc aaataaatac 16741 aggcattctc ttctttctaa atagagaatg cctgcttttt tatgcccgag tacttgattg 16801 gttactgtta aaaagtttat tccataccta caactgcttc aacgcaagct ccgtcaagtt 16861 ctctacagta aagccaaatc gtcttgctag ctcatctccc gggccagaca taccaaacga 16921 atcaatcgcg aggatttggc ctgtgtcgcc gaggtatttg tgccagccgt atgatgcgcc 16981 catttctgcg gcgaagcgat ttttcactgc ttttggtaaa acggactctt tatattcagg 17041 gctttgtttg tcgaataaat caaagcttgg catgctgact acgcgtgctc cgaagccttt 17101 tttagcgaga ttatctctga cagctgtcat taggtgtact tcggatccag aagcgagtaa 17161 gataatatct agtttatcaa gcggggaatc ggctaagatg taagcacctt ttgcaagtcc 17221 ggtttgcgct tttgctgcgc tatttggtaa aattggcagg ttttggcggc taagaacgag 17281 catggttggt tgttcttttt gagtaaaggc atagcggtat gcttcgacgg tttcgttgcc 17341 gtcagctggt cggatgacgt gaagtcccgg catggcgcgg aaggatgcga gatgctcgat 17401 tggttcgtgc gttggaccgt cttcaccgac tgcgatggaa tcatgggtca tgatgaaagt 17461 ggatggaatg cccattaaag ctgctgaacg aatcgcggaa cgtagataat ccgagaatac 17521 gaagaaggtt gcgccgaaag cttgaacacc gccgtgaagc gtcattccgt tgactgctgc 17581 tcccattgcg aactcgcgga cgccgaatga gatatttttg gcggcatagt tacctggagc 17641 aaaccgttcg ctagctttta aatgggtttt attggaggag gccaaatcgg ccgcgccacc 17701 aaataggtta ggcagttttt tctccaattc ttgtagaaca attcctgata cttcacgggt 17761 tgcaacggct ttgtccgcat tttcatcgaa gacaggaagt tctgcatccc aatccgcatc 17821 caaattatca tccattaatt gttgcaaact ttctgcgagt gctggatatt tttgtttgta 17881 agcattgaat gtccggagcc agctgctttc actcgcgcga cctttagaat gataaaattc 17941 tttctgattt tcgacagttt ttggtaattc aaaaggtggc atttgccaat cgtaagcttc 18001 ttttgcaagt ttgagttctt tttcgccaag tggggagccg tgtgccgccg attttccggc 18061 tttaccaggg ctaccgtaac cgatgaccgt tttcacttcg attaaagtag ggcgggattt 18121 ctcggttttt gcgagatgga ttgctgcatc aagcgcatct aagtcatttc cgtcgtccac 18181 acgtagcgtt tgccaaccgg ctgctcggaa tctgagttcg atgtcttctg aaaaagactc 18241 gtttaaatcg ccatccagtg agatatcatt cgaatcatat aaaacaacta attttcccag 18301 ttttaaatga ccagcaaggg atgcagcttc gtaggaaata ccttccatca aacagccgtc 18361 tccgcatagc acgtaggtat tatggtcaac aaccgggaat tcaggttggt taaatttggc 18421 gccaaggtga gcctcggcca tcgccatccc aactcccatt gcgaaacctt gaccaagtgg 18481 accggtagtt gcatcgacac caaccgtatg accgaattca ggatgaccgg gcgttttact 18541 accagtttgg cggaagtttt tcagctcgct cattggtaaa tcataaccaa atagatgtag 18601 caaactataa agcattgccg aaccgtgacc agctgacaaa acgaagcgat cgcggttaaa 18661 ccaagttggg tgttctggat tgaattttaa atgatttttc caaagcgaga aagccattgg 18721 tgcggctccc atcggcaaac cgggatggcc ggagttcgct ttttcaatca tatccattga 18781 taatacgcga atcgagttaa ccatttgttc atcaattctg ctcat //