LOCUS AP010958:12 18548 bp DNA linear BCT 27-AUG-2011 DEFINITION Escherichia coli O103:H2 str. 12009 DNA, complete genome. ACCESSION AP010958 SOURCE Escherichia coli O103:H2 str. 12009 DNA, complete genome. COMMENT locus start: 2455052; locus end: 2473599 FEATURES Location/Qualifiers source 1..18548 /organism="Escherichia coli O103:H2 str. 12009 DNA, complete genome." gene complement(0..950) /gene="cbl" /locus_tag="cbl" /db_xref="2455052..2456002" CDS complement(0..950) /gene="cbl" /locus_tag="cbl" /product="DNA-binding transcriptional activator Cbl of cysteine biosynthesis" /translation="VNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA FPWFRWHHSLLVPHDHPLTQISPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLLA DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEENLIRLDTRHLFDANTVWLGLKR GQLQRNYVWRFLELCNAGLSVEDIKRQVMENSEEEIDYQI" gene complement(1052..1969) /gene="nac" /locus_tag="nac" /db_xref="2456104..2457021" CDS complement(1052..1969) /gene="nac" /locus_tag="nac" /product="DNA-binding transcriptional dual regulator Nac of nitrogen assimilation" /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN QQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQALSGQVSIGFAPGTA ASSITMPLLQAVRAEFPEIVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA LLKEDLFLVGTQDCPGQSVDVNAIAKMNLFLPSDYSAIRLRVDEAFSLRRLTAKVIGE IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL SPQAQAVKELLMSVISSPVMEKRQWQLVS" gene 2296..2371 /gene="asnV" /locus_tag="asnV" /db_xref="2457348..2457423" CDS 2296..2371 /gene="asnV" /locus_tag="asnV" /product="tRNA-Asn" /translation="SSVVQSVERRTVNPYVTGSSPVRGA" gene complement(2426..3358) /gene="erfK" /locus_tag="erfK" /db_xref="2457478..2458410" CDS complement(2426..3358) /gene="erfK" /locus_tag="erfK" /product="conserved hypothetical protein ErfK" /translation="MRRVNIFCSFALLFASHTSLAVTYPLPPEGSRLVGQSFTVTVPD HNTQPLETFAAQYGQGLSNMLEANPGADVFLPKSGSQLTIPQQLILPATVRKGIVVNV AEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYAK RGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKYL FDNVPVGTRVQIIDQPVKYTTEPDGSNWLEVHEPLSRNRAEYESDRKVPLPVTPSLRA FISGQEVDVNRANAALQRRSGMPVQISSGSRQMF" gene complement(3423..4502) /gene="cobT" /locus_tag="cobT" /db_xref="2458475..2459554" CDS complement(3423..4502) /gene="cobT" /locus_tag="cobT" /product="nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase" /translation="MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAI QLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL AAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRHQAEKLLLDVICYT RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRAPEEVVGIGANLPTDKLANKIDVV RRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAAC QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACA IYNNMGELAASNIVLPGNTTSDLNS" gene complement(4514..5257) /gene="cobS" /locus_tag="cobS" /db_xref="2459566..2460309" CDS complement(4514..5257) /gene="cobS" /locus_tag="cobS" /product="cobalamin 5'-phosphate synthase" /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL GAISGLVFMVLQAWCGAPLAALFSVLVLVLMTGGFHLDGLADTCDGVFSARSRDRMLE IMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL LKRTLGGQTGDTLGAAIELGELVFLLALL" gene complement(5254..5799) /gene="cobU" /locus_tag="cobU" /db_xref="2460306..2460851" CDS complement(5254..5799) /gene="cobU" /locus_tag="cobU" /product="bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase" /translation="MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARI EHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDPDE WDYQAMEQVINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ QLAAAANEVWLVVSGIGVKIK" gene 7459..8004 /gene="" /locus_tag="" /db_xref="2462511..2463056" CDS 7459..8004 /gene="" /locus_tag="" /product="" /translation="MRDEILYNIPCRIYILSTLSLCISGIVSTATATSSETKISNEET LVVTTNRSASNLWESPATIQVIDQQTLQNSTNASIADNLQDIPGVEITDNSLAGRKQI RIRGEASSRVLILIDGQEVTYQRAGDNYGVGLLIDESALERVEVVKGPYSVLYGSQAI GGIVNFITKKGESPDSLYHLN" gene 9155..9271 /gene="" /locus_tag="" /db_xref="2464207..2464323" CDS 9155..9271 /gene="" /locus_tag="" /product="" /translation="MFFDGERSALLYGLIGTCLLNDIDPEEYLRHILSVLPE" gene 9734..10681 /gene="" /locus_tag="" /db_xref="2464786..2465733" CDS 9734..10681 /gene="" /locus_tag="" /product="putative carbohydrate kinase" /translation="MKSQVCVIGSFNVDIISYLPRLPTIGESLLASNFIFSPGGKGCN QALAASFADTDVYFITKVGTDHFSDYAINFMNSSKIYKSIIYQTKETQTGTATILVNE GTGDNVIAIYPGANMTMSSDEITIQKEAIINSDVILLQLETNYTALQQAITLAQKNSI PVIINPAPYNDIVNELIQDVDYITPNETEAGLLSGIDVHDLESAKRAAEAIHNKGVKN TVITLGSKGSLAFDGKKFIHSPAFPAVVKNTAGAGDAFNGALASGLAKGKSLESALCY ASAFASLAVETSNASDMPEHESVIHRIQSIHYQQTIFTH" gene 10695..11453 /gene="" /locus_tag="" /db_xref="2465747..2466505" CDS 10695..11453 /gene="" /locus_tag="" /product="putative cytoplasmic protein" /translation="MNNTKKSLKVLFIGESWHIHMIHSKGYDSFTSSKYEEGATWLLQ CLKNSQVDVTYMPAHTVQIAFPEDVAQLEQYDAIVISDIGSNTFLLQNDTFYQLRIKP NALELIKEYVNNGGGLLMIGGYLSFMGIEAKANYKNTVLADVLPVTMLDGDDRVEKPE GVIAQPSQPDHPVIKGFSEYPFFLGYNRAIAKENAEVVLTINNDPLLVFGNYHNGKIA CFMSDCSPHWGTQQFMSWPFYTALWVNILTHIAR" gene 11510..12475 /gene="" /locus_tag="" /db_xref="2466562..2467527" CDS 11510..12475 /gene="" /locus_tag="" /product="putative membrane protein" /translation="MKKNKYSTPLWVLATILAGMLSPMQSAVNGQLGHWLQDGNACAV ISFASGLVVMFFIIMARKEIRQQFAAIPSLIKNRKVPLWNWFAGLCGAMVVFSEGASA SALGVATFQTALISALLLSGLLCDRFGIGVDEKKYFTPYRIIGALFAVIATIFVVSPQ WHSTSFILLAILPFLAGLLAGWQPAGNAKVAEATGSMLVSITWNFIVGFCVLGTALAI RVALGHVTVQLPDVWWMYLGGPLGLMSIGLMAILVRGLGLLMLGVASTAGQLLGSVLI DVLIPSLGNTVYLVTIIGTLFALVGAIVTTIPEYRASKTMKKMEV" gene 12478..13512 /gene="" /locus_tag="" /db_xref="2467530..2468564" CDS 12478..13512 /gene="" /locus_tag="" /product="putative phosphotriesterase-like protein" /translation="MKDYLQTVTGPVAREDMGLTLPHEHLFNDLSSVVDAPCYPFSQQ LVDKKVTAEIQWALKHDPYCCADNMDRKPIEDVIFEINNFISLGGRTIVDATGSESIG RDAQALREVALKTGLNIVASSGPYLEKFESQRIHKTVDELATTIDKELNQGIGDTDIR AGMIGEIGVSPTFTEAEHNSLRAASLAQINNPHVAMNIHMPGWLRRGDEVLDIVLGEM GVSPNKVSLAHSDPSGKDVAYQRKMLDKGVWLEFDMIGLDITFPKEGIAPGVQETADA VAHLIELGYADQLVLSHDVFLKQMWAKNGGNGWGFVPDVFLAYLAERGVDKTILKKLC IDNPGRLLTA" gene complement(14164..15147) /gene="" /locus_tag="" /db_xref="2469216..2470199" CDS complement(14164..15147) /gene="" /locus_tag="" /product="" /translation="VGLRCSADTLLRRLINTPETKQSGAPHVGIDEWAWHRGHCCGML IVNPDTHRPLVLLPGRDQRTLATWFRKYPEIQVVSRDRSGVYATAAREGAPQARQVAD RWHLLKNIGDEPERMMYRYMPLIRLVVRELSLKKSPEPEISVPVASLRRLERLKQHIR KKRHQRWTEVMALHNKGCSFREISRITGLSRVTVSRWVGSGTFPEMSTRPPKRGLLDP WREWLKEQRECGNYNSGRIWREMVARGVTGSETIVRDAVAKWHKGWIPPVTTAARLPS VSRVSRWLMPWRIIRGEENYAFRFISLMCEKEPELKIAQQLVLEFYRILKT" gene complement(15827..16234) /gene="" /locus_tag="" /db_xref="2470879..2471286" CDS complement(15827..16234) /gene="" /locus_tag="" /product="conserved predicted protein" /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM CDENYEGEKCCPSCGTGVYSREGGQEGNWKDRN" gene complement(16222..16623) /gene="" /locus_tag="" /db_xref="2471274..2471675" CDS complement(16222..16623) /gene="" /locus_tag="" /product="conserved predicted protein" /translation="MYAKSFIALDGNGRLTGARTAQAAPYANYTCHLCGSALRYHPQY DTELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVLDALPVVRKASWHCRQC HHDYYGERYCTHCQTGGFSIPRTTQEEICEF" gene complement(16883..17452) /gene="" /locus_tag="" /db_xref="2471935..2472504" CDS complement(16883..17452) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRFPDVPAATD AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGECKGKKHYHLMLLVN RDTWCRAGDYRAPGSLAGMIKQAWCSALGVDVGCHATLVHFPAWPAVWLERDDDTGFQ QVLERADYLAKEHTKAHCTGERNFGCSRS" ORIGIN 1 ctatatctga taatcaattt cctcttcact gttttccatc acctgccgct tgatatcctc 61 aactgacagt cctgcattac aaagttccag aaagcgccag acatagttac gctgaagttg 121 tcctcgcttc agtcccaacc agacagtatt agcatcgaaa agatgccgcg tatccagacg 181 gattaaattc tcttcctctt gttcgccgct ggattgttcg gcaactaatc cgatcccaag 241 cccaagagca acataggttt taatgacatc agaatcctgc gcacttaata caatatctgc 301 cagcaaacct ttgcgggcaa atgcgtcatc aatacgtgag cgccccgtaa tcccctgtcg 361 gtaagtgatt aacggccact tcgctattga ttccagcgtc aatggtgaaa tttgcgtcaa 421 gggatgatcg tgtggaacaa gcaaactatg gtgccaacga aaccacggga aggcgacgag 481 ctgcgggtca ttactcaaac gctcgctggc gataccaata tcagcttcgc cattttgcaa 541 caatgtcgca atttcctgtg gcgtcccctg gattagctcg agccgaacct ccgggaaaag 601 ttcgcgaaaa gctttaatga cctctggcaa gctataacgt gcctgagtat gcgtcgttgc 661 aatagtgaga acgccagacg tatcgttggt aaacaggtct gcaagccgac gaacattact 721 ggcttcattc agaatacgtt ctgcaatgac cagtaatgct ttgcccggtt cagtcatgcc 781 cagcagtcgc ttacctcgtc gaacaaatat ttcgatgcca agttcatcct ccagttcccg 841 aatatgacgg ctgacgcctg actgtgaggt aaaaagcata ttcgcaacct ctgtcaggtt 901 gtaatcctga cgtgcagcct cgcggattat ctttagttgt tggaaattca cggtaaactc 961 cgggcagttc agatttcccg ttattgttaa agtctaatgc ccggcataac aaataataaa 1021 aacccgcatc ttattccatc ccgatataac acttagctca ccaattgcca ctgccttttt 1081 tccatcactg gagaactaat cactgacatt aacaactctt tcactgcctg tgcctgtggc 1141 gataagttcg ctctggcggg taaatttaat gacaaagaga gactcatgga aggagtggta 1201 atgcgtgaca tccacccatt tactgcgcca cataacgaac gcgcggccga ttcgggtaat 1261 actgcaacgc ccatgccgct ggcaatcgct gcggtaagcg tggcaataga ctcaatttca 1321 ccaataactt ttgccgtgag tcgccgtagg gaaaaagcct catcaacacg aagtctaata 1381 gcactgtaat cactggggag aaagaggttc attttcgcaa tagcattcac atcaacgctt 1441 tgccccgggc aatcttgagt tcctaccaga aaaagatctt ctttcagcaa agcctgactg 1501 gatacaccag ccacagggga atgctcataa atcaccgcca tatcgagttg gtgatttatc 1561 aatttttcgt taagcactgc accactattt tcatgaagat agataacgat ctccggaaat 1621 tcagcgcgaa ccgcctgtaa taagggcatg gtgatggatg acgcagcggt tcctggtgca 1681 aagccaatcg agacttgccc cgataatgcc tgaccaacgt tatgcaccgc cagttgggcc 1741 tgttcacact gacgtaaaat ggcccgcgca tgggtataga gaatttttcc ggcgtctgtt 1801 ggcgtaacgc cccgctttgt acggatcaaa agttgttgat ttaactcacc ttccagtgtg 1861 gcaacctgct ggctgagcgc tggttgtgcg atatgcaata cttcagcagc ctgggtcagg 1921 ctaccaatat ctacaatttt tacgaagtat ttcaggcgtc tgaagttcat gttgcctccg 1981 gtttttaaga atcggcccaa gtgccgctat tacttacaac cagattgcaa gatgcttgcc 2041 agttttattt tggcgttgat gtacaagcta accaactgtc aaataagaga ttatgataga 2101 ttcgtcattt gctcctttaa tcagctgtcg cgttcccctg ccctataaaa ggagggtatg 2161 caccacgatg gttcattacc caataagatt gaaagctcac cactttgttg aaattgacag 2221 caaacaaaca aaaaaatgca tttcaccctt tgacatcacc atgcactgcc attaatatgc 2281 gccccgttca cacgattcct ctgtagttca gtcggtagaa cggcggactg ttaatccgta 2341 tgtcactggt tcgagtccag tcagaggagc caaattcaaa aaagcctgct ttctagcagg 2401 cttttgcttt ctaattacca acgctcttaa aacatctgtc ttgaaccaga actaatttgc 2461 acaggcattc ccgatcgacg ttgcaacgca gcatttgcgc gatttacatc aacttcttgc 2521 ccgctgataa acgcccgcaa agatggggtt accggcaatg gcacttttcg gtcagactca 2581 tattctgcac gattgcgcga caacggctca tgaacttcca gccagttcga gccatctggt 2641 tcagtggtgt attttactgg ctggtcgata atttgcacac gcgtcccaac aggaacatta 2701 tcaaacagat atttgatatc gtcattgcgc agacgaatac agccctgact tacccggagc 2761 ccaataccaa aattggcatt ggtaccatgg atggcataca acctgccaat ataaatcgcg 2821 tacagcccca tgggattatc ggggcccgca ggaacaaatg cgggcaaact ctcccctcgt 2881 ttcgcatatt cgcgccgagt gttcggcgtt ggcgtccagg ttggagcttc ttgtttacgt 2941 tcaacggtag tcacccagtt acgcggggtt tctcgcccag cctggccgat accaatagga 3001 aagacttcca cagtattact gtctggtggg tagtaataaa gacgcatctc agcgacgtta 3061 accacaatcc ctttacgaac agtggcgggc aaaatcagtt gctgcggaat ggtgagttgc 3121 gagccagact tcggcaaaaa aacatcagcg cccgggttcg cttccagcat gttacttaac 3181 ccttgcccgt attgtgcggc aaaagtctcc agcggctggg tattgtgatc aggaacagtt 3241 acagtaaacg actgccccac taaacggcta ccctctggag gtaatggata agttacagcc 3301 aggctagtat ggctggcaaa aagcagagca aatgagcaaa aaatatttac acgacgcatc 3361 atgtcccttt cctaagtcgc gaaagctatc cgttaagtat agcttttatc agacttttcg 3421 tttttaactg ttcaaatcag aagtcgtatt ccccggtaga acaatattac tggcagcaag 3481 ttcgcccatg ttgttatata tcgcacaggc agcttcgatg atgggcatcg ccagagctgc 3541 gccactcccc tcacctaaac gcatctccat attgagataa ggctccagcc ccaaatgcga 3601 cagcgcaata cgcgcccctt tttctgccga caggtgagaa ggaatgagat acggtttgat 3661 tgcaggagac atctggcagg ctgcgagcgc ggcagcataa gaaagaaatc catccagcaa 3721 cacgggtaaa ccgcaggaag cagcgcctaa catcacgcca gccattccga ccaaatcaaa 3781 tccacccact tttgccagga catcaacgcc atcctgcgga tttggttgat tcaacgtaat 3841 cgcccggcgc acaacatcaa ttttattagc cagtttatct gtcggcaggt ttgcgccaat 3901 cccaaccact tcttcaggag cccggccagt gattgtgctg actattgccg ctgccggtgt 3961 cgtgtttgcc atccccagtt cacctacacc aaacagcgta acaccgtttt ttgccagctc 4021 ccgcgtataa catatgacgt ccaaaagcaa cttttctgcc tgatggcgac tcattgccgg 4081 agctgaagca atattgccac tacctcgagc aacacgcatg ttgataagcc cggggatagg 4141 ctcagcagta tcaataccaa catcaattac gtagacgtta gcgcccgctt gtgctgccag 4201 cacacacacg ccggttgttc cgcgggtcat attttcagcc tgaatggctg tcacttcttt 4261 tggggaaata gcgacccctt cctcccagac gccgtgatcg gcacacataa ccagtaccgc 4321 ttttttgccc acatgcggta tgccattcaa ccccggcatt cctgccagtt gtatggcaag 4381 cgcctccagc cttcccaggc taccaacagg tttgagtaac ccgtcaatat gccgttgtgc 4441 acgcgacatc gcggcaggat cgatggcagg gatcgtattc agtaaatcgg caagtgtttg 4501 catgtcacgt ctctttatag cagtgccagc aggaagacca gttcaccaag ctctatagca 4561 gctcccagcg tatcgccggt ttgcccgccc agcgtacgtt tgagaagctg accgaggatg 4621 aaaatcgcca ccatcgtcac caccatagca gccacaccat gcatacccgg caataatacg 4681 gcagcaaaaa tagcggctaa gccgagtgtg acgcaggttt gtcgcccatc aattttgcca 4741 atgaacacat tgccaagccc ttcttcccgg gcataacgat gacgatacat caataatgcg 4801 gcagtcccgc ggctgaccgc acatgctgcc gccagcgatg caaggatcgg ttcgccacgc 4861 agagccaact cgcttaacac cagaatcttt gccagtacca caaaaatcaa tgccagaccg 4921 ccgtgggtgc ctaaacggct atcacgcatg atttccaaca tgcgatcgcg gctacgtgca 4981 gaaaatacgc catcacaggt atcagcgagg ccgtccagat ggaatccccc ggtcatcagc 5041 accagcacaa gtacgctaaa cagtgccgcc agtggtgcgc cacaccatgc ctgcagcacc 5101 atgaagacca gcccgctaat cgcgccaagc aataatccaa tcaaaggaaa agtaataata 5161 ccgcgagaat aatgctcgaa atccagtccc tgggaccagc gacgcggtac aggcagacgc 5221 gtaataaatg agagcatcgc ccaaaataat ttactcattt gatttttact ccaatacccg 5281 aaaccaccag ccatacttca tttgccgcag cggccaactg ctgatttacc cgcccggcaa 5341 tatcacgaaa atgtcgtgcc agacgactct ccggcacaat ccccattccc acttcgttag 5401 tcactaatac aacctttgcg gggcaacgtt ggcaggcagc aatcaacgac tgaatctcag 5461 cattaatcac ctgttccatc gcctgataat cccattcatc agggtcttta tcgccgccat 5521 aatcaaacaa cagattagtc accattgtgg taacgcattc aagcaacaca acctcattcg 5581 ggttaatgtc tgcatgaatt aattcatcaa gatgttgcca gcgctccact gtgcgccagt 5641 gctccgggcg gccttgccga tgatgttcta tccgtgcagc catctcatca tcaaggattt 5701 gcgaggtagc gatatacaga acctgtgaag agtccccaat aagcgcctct gcgtggcgac 5761 tcttcccgct ccgtgcgccc cccgtcacca aaatcatcat accgactcct gattcaaatg 5821 tatgatggta ttcattgaac agaacaatgg atcccccacc gttgctgacc gcaaaacatt 5881 tacgcgatta atactgcgcg taatataatt aaaaatccag cattctcaat ccattacgaa 5941 ataagatggc attacggaat agccagactt tctcgtgtta acgtccgaca aaatgcgtca 6001 ttgacagcgg tttctgtgga ttgacacatt tcattcagat aatgaattaa tgctactgcc 6061 ggaacaacca gcaaacgggc attgtgttct gaaatccagg ctattgattc aacgtcagcg 6121 acagatctgc gctgtaaaag aacttgtaaa acaacgtaat agaattatcc ggaatggtgg 6181 cgactatgca ctagaacacc acaatttcgc tctctcggta aggcactgtc acagcattca 6241 acagaatgtg acttgccaga tttattagcg ccaccagatg tttaaccggg taaccacgac 6301 ccagtcgggg atatattcca tcttctcgct gacatcatca agaataaaaa ggtttatcac 6361 actcagagca acgttcttca gcaggcggga taattcttca acatttagaa gatgtgttat 6421 taaaggcata caaactggac gtattgtatt ttcttttggt ggttgaccta aggtagcagt 6481 ttatcctgat gcgctgagat ttctgtaata tctacgtcaa cattctcctc gaatagaaaa 6541 tgcagccccg gcaagtgatt cacatttttt aacaaaacgt tgttagcgtg ccattttcag 6601 aagctctcca agaaagcgaa ttcttttctc aaattctgca ttctcagaca cagctttcta 6661 ctccatggta atggcccaaa tacgaagttg ctcaggatca ttagtggtgc tgagaagtta 6721 aataaccatg cggagtacca ctcgtcatca cgtatttata tatcatgaag ctattgttgt 6781 gttttgtaca tcagtagata tattctgata tactcctttt gctagacata acctttcacc 6841 tgcttgcaaa gcttctgtgt tctgacattg ccaaattgtt gcaattctgt atccagcctt 6901 ctttcagtca tagcttcggg ccgcgataag actcactgat ctgaccctga ttcctcttgc 6961 agactttata gaccaattaa aatgcagttt ctgcaggtca acgtctgacc atcattgtca 7021 tcactctggc cattagagta accttctgca ttcatccttt tgtaaaaagt ttatattagt 7081 atcagcaatt aaccggacct gatactgata tgagtcttac cgcatatacg gtcaatttca 7141 gcaattaatt acattatcca cgccaaagta tttgtcatca caatgatggt accttctttc 7201 agacaccatt ttttcaactc cgttttccac ggaccgcact cttatgtcaa gagtgcggtc 7261 cgtggataca accagagacc gactgacacg agtcagagga aacgacggat atgttcagtc 7321 gtaaaatatc tatcaaaaaa catgattaag gtcaaaaatg tttgatattt acaatttatg 7381 aagatgacaa taattataga tatatgagaa cataaatgaa aataattatc attacagcaa 7441 tcatttgtac tttgtattaa tgagggatga aatattatat aatatacctt gtcgaattta 7501 tatcctttcc actctgtcat tatgcatttc tgggatagtt tctactgcaa ccgcaacttc 7561 ttcagaaaca aaaatcagca acgaagagac gctcgtcgtg accacgaatc gttcggcaag 7621 caacctttgg gaaagcccgg cgactataca ggttattgac caacaaacat tgcagaactc 7681 caccaatgcc tccatagccg ataatttgca ggacatcccc ggagtagaga taacagacaa 7741 ctccttggca ggccgtaaac aaatccgcat tcgtggcgaa gcatcctccc gtgttttaat 7801 tctcattgat ggtcaggagg taacttatca gcgcgccgga gataattatg gtgtgggact 7861 gttgatagat gagtctgcgc tggagcgtgt tgaggtagtg aaaggtccat attccgtact 7921 gtacggttca caggcaattg gcggtattgt taacttcatc accaaaaagg gtgaatctcc 7981 ggactcccta tatcacttaa attgatacaa ctttttagag tagtcattag tgaacagata 8041 attgataact cagaaccagt aaaatgcaaa agacgcacca cgctgggaaa atcgctgcta 8101 ttcagcagag ttttgtatcg agaatggtgg ccagccactt attgctctcg cgtaagcggg 8161 tatccccatc gtttaccagt ccagatatag gtcacgtcac catacttgat ttagctgtgt 8221 cacagctaag cgcccttcaa gttcttagga tagctacaag ttcatgactg ccatgcctgt 8281 accggagggt caacggctga cagctgacca gcccctgttc tttcatgaga ctgccagcaa 8341 gcttgcgtcc cgtctggtag tctctccggg ttgcaattgt ggcgatgttc cttgctccgc 8401 cattaagctc aattacctga ctacgtaata cagcccgtct accgtctttt tttcaggacg 8461 gtttttccaa tctctgtagc tgcttcgatg aatcctgcac acatggcaga gtgctatcac 8521 cagataatgc gctctgagct tctcgattat cgagaactgt ttagggagtc tgacatcaag 8581 agcgccgtag ccttttctaa tatttcattc tctatttcaa tacgttgccg ctttttcctc 8641 agctcacgta tttcgatttg ttctggtgtc atcagagagg cttttggtgt tttgctctga 8701 tgctcattac gcagttgttt gacttatctt gtcattgtgg aaagaccgac atccatagct 8761 ttggatggta cctgccaccg taaagttctg gttaacaact agttgagtgg attcgcgttt 8821 aaactctgcg ctgaaatttc cttttttcat tggagcatct gtgttgttct aaggtgagca 8881 tattacctat gctcaggtgg ccaaattcag tatgccagaa ccagaacatc ttgtggtcag 8941 gcagaggaag agcaaactgt tactggactc actgcatgcg tggatggtgg agaaaaatgc 9001 cacgctgtcc aaaaatccag actgggagaa tggttcagct gtgtactgaa tcagtggggc 9061 gcactctgtt attacagtgt tgacggtcag gcggaggcag acataatgcc gcggaaaaag 9121 ccctttgtgc catctgtctc ggaaataaaa actttatgtt cttcgacggc gagcgcagtg 9181 cactgttgta tgggcttatc ggcacttgcc ttctgaacga cattgatccg gaagagtatc 9241 tgcgccatat cctgagcgta ctgccggaat aaccttccaa ccgtattgat gaactcctgc 9301 catggaacgt agttctcacc aataaataag catcaatatg attctccatt aacgcttacc 9361 ttttctccgg ctatttttga ttttttttgc ttttccccgc cactttatgg tgattatcac 9421 atcaatatac atcgacagat attaacgtaa ctgaagtgag gtgaagcatg aaatttgaac 9481 gccatcatga aatattgaaa cgactcagta aattcggttc tgtaaaagta tccgatctgt 9541 ccaatagcct caatgtaacg aaagaaacta ttcgatcaga tcttaatgaa cttgccagac 9601 ttggctatct gactcgatat catggcggtg cttttatcgt cctagactcg cttgatacta 9661 ttgcgaaaaa tgaaatcgct tatgcgcttg aaaattatga tacagcctag ggaataaaaa 9721 aaggccactc aactatgaaa agtcaagtat gcgttattgg ttcgtttaat gttgatatca 9781 tcagttattt gccgaggctt cccactatcg gagaatcgct tctggcaagt aattttatat 9841 tttcaccggg gggaaaaggt tgtaaccagg cgctggcagc aagctttgcc gatactgatg 9901 tttatttcat aacaaaagta ggtacagatc actttagtga ttatgcgatc aactttatga 9961 attcgtctaa gatttataaa agtataattt atcaaacgaa agaaacgcaa accggaactg 10021 ccacgatcct tgttaatgaa ggtactggcg ataatgttat tgcgatctat cccggtgcca 10081 acatgacaat gtcgtccgat gaaataacta ttcagaaaga agcgattatt aattctgatg 10141 tcatacttct gcagctcgaa acaaattata ccgctctgca acaagcgatc acattggcgc 10201 aaaaaaacag tatcccggtc attattaacc cggcacccta taatgatatc gtcaacgaac 10261 ttattcagga tgttgattat atcaccccca atgaaacaga agctggttta ctgtccggca 10321 tagacgtaca cgatcttgaa tcagctaaac gagctgcaga agctatccac aataaagggg 10381 taaaaaacac cgttatcacg ctcggtagca agggctcgct cgcatttgat ggcaaaaaat 10441 tcattcattc gccagcgttt ccagcggtcg ttaaaaatac ggcaggagcc ggggatgctt 10501 ttaacggcgc tctggcatca ggacttgcga aaggaaaatc actggaatca gcactgtgtt 10561 atgccagcgc ctttgcatcc ctagcggtgg agacaagcaa tgcttccgac atgcctgaac 10621 atgaatctgt gatacatcga attcagagta tacattatca gcaaactatt tttacgcatt 10681 aagaagggac agagaatgaa taacaccaaa aaatcactaa aggtgctctt tattggagaa 10741 tcctggcata ttcatatgat tcattcaaaa ggatatgaca gttttacctc aagtaaatat 10801 gaagaaggtg cgacctggtt actccaatgt ctgaaaaata gtcaggtaga tgtcacctat 10861 atgccggcac atacggtaca aattgccttc cctgaagatg tggcacagtt agaacaatat 10921 gatgccatcg ttattagtga tattggtagt aatactttcc tgctacaaaa tgatactttt 10981 tatcagcttc gcataaaacc aaacgctctc gaactgatta aagaatatgt gaataacggt 11041 ggtgggttat tgatgattgg cggctatctc tcattcatgg gaattgaagc aaaagccaat 11101 tataaaaata cagttctggc tgatgtgctc ccggttacga tgttagatgg tgacgatcgt 11161 gtcgaaaaac cagagggtgt tattgcacag ccatcacaac ctgaccatcc ggttattaaa 11221 gggttctctg aatatccttt tttcctaggt tataaccggg cgatcgctaa agaaaatgct 11281 gaggtggtat taacaataaa caacgatcca ttactggtct ttggtaacta tcacaacggg 11341 aaaatagcct gctttatgag tgactgttca ccgcactggg gtacacagca gtttatgtcc 11401 tggccgttct ataccgcgtt gtgggtaaat atactgactc atattgcaag ataataataa 11461 taatggggta acaccagtta ctccatttac tataatagaa ggattgatgt atgaaaaaga 11521 ataagtactc aactccctta tgggtgcttg ccacgattct tgcgggtatg ctctccccta 11581 tgcaatcagc ggtgaatggt caattaggtc actggttaca ggacggtaat gcatgcgcag 11641 ttatctcctt tgccagtggt ttagtcgtga tgttttttat tattatggcg cgaaaagaaa 11701 tccggcaaca atttgcggca attccttctc tgattaaaaa ccgaaaagtt cctctctgga 11761 actggtttgc cggtctctgt ggagcgatgg tggtattttc tgaaggcgca tcagccagcg 11821 cactcggggt cgcaacgttt cagaccgcac tgatctccgc gctattgctg tctggtttac 11881 tttgcgatcg ctttggtatc ggtgtcgacg agaaaaaata ctttacccct tatcgcatca 11941 tcggtgcatt atttgcggtt attgctacga tttttgttgt gtcaccgcag tggcattcta 12001 cctctttcat tttacttgcc attcttccgt tcttagctgg tttgcttgca ggatggcagc 12061 ccgctggaaa tgcaaaagta gctgaagcta cgggatccat gctggtttca atcacctgga 12121 atttcatcgt tggattttgt gttttaggca cagcgctagc tattcgtgtc gcattagggc 12181 acgtcactgt tcaattacca gatgtctggt ggatgtatct tggcggcccg cttggactaa 12241 tgtctatcgg tttaatggcc attttggtca ggggtctggg gttactgatg ctgggggttg 12301 cttcaacggc gggccagtta ctgggatcag tattgattga cgtattaatt ccatcgctgg 12361 gcaataccgt ttatctggtc acgatcatcg gaacactgtt tgcactggtc ggtgcaattg 12421 ttaccactat tccggaatac agagcctcga aaacaatgaa gaaaatggag gtataatcat 12481 gaaagattat ctacaaactg tgacgggccc cgtcgcccgt gaagatatgg ggctaacact 12541 tcctcatgaa catctgttca acgatctttc ctctgttgtg gatgctcctt gctatccttt 12601 ttcacaacag cttgttgata aaaaagtcac ggcagaaatc cagtgggcat taaaacacga 12661 tccttattgc tgcgctgata atatggaccg caaacctatt gaagatgtga tcttcgaaat 12721 taataacttt atctcgctcg gtggtcgcac cattgttgat gccacagggt ctgagtctat 12781 cggacgagat gcgcaggcat tacgagaagt cgcattaaaa acaggtctga atattgttgc 12841 ttcctccggt ccctacctgg aaaaatttga aagccagaga attcataaaa cggttgatga 12901 actagcgaca acgatcgata aagaattgaa tcaagggatt ggcgatacgg atattcgtgc 12961 cggaatgatc ggtgaaatag gtgtctcacc gacatttacc gaagccgagc ataacagctt 13021 gcgggctgcc tcgctggcac agattaacaa tcctcatgtg gcgatgaata ttcacatgcc 13081 gggctggctt cgtcgcggtg atgaagtact cgacattgtg ttaggtgaaa tgggcgtctc 13141 gccaaataaa gtctctctcg cacactcgga tccgtcagga aaagacgtgg cgtatcagcg 13201 gaaaatgctt gataaaggtg tctggctgga attcgacatg attggcctag acattacctt 13261 cccgaaagag ggaatagcgc caggggtgca ggagactgcc gatgccgtcg ctcatctcat 13321 tgagttggga tacgccgatc agcttgttct cagccacgat gtcttcctta aacaaatgtg 13381 ggctaaaaat ggcggtaatg gctggggatt tgttccagat gtttttctgg cctatctggc 13441 ggagcgcggc gtcgataaaa cgatcctcaa aaaactctgt atcgataatc ccggacgatt 13501 attgaccgca taaaaccatt atcccccggc acattgcgcc gggggatgtc aattaatacc 13561 ccgccgttaa atcatccacc aagcgcgagt cggatgcgcc gtacaactca ccatccgacc 13621 caaccataat gctttgcgtg ctgcccatcg cctcattcag cgccactttc tgaccttttg 13681 cttccagcag cttgagcgta tccggactaa acccttttca acacgcagct cgtccggcaa 13741 ccactgatgg tggaaacgag gcgcattggt cgcttcggca acattcattc cacaattgat 13801 gctgttcacc accatttgcg gcacggtagt gatgatccag ctaccggtaa caaagtgagt 13861 acataaaggc catactgtca cgaacagtgc aaaagtggct cttcctcaac ctaggtgaag 13921 attttcatgc cagtggactc attaccctcc gcctaagtag ttcaagtccg gctcgaccat 13981 acatctggcg tatcagcacc ttcaggcgat ttacatgacc ttcgacaaca ccagtactcc 14041 agcgactgct gattgcctca catatagccg cagcatcagc ttccatcccc gcagctacgc 14101 accgaagttc tgctgagccg ctttcgtgga cccgagtgaa ccagctgctt agctgtgatt 14161 tattttaggt tttcagaata cggtagaact cgagtaccag ttgctgcgct attttcaact 14221 ccggttcttt ttcacacatc agactaataa atcggaacgc ataattttct tcacccctga 14281 ttattctcca gggcatcaac cagcggctta cccgggacac tgaaggaagt cttgcggcag 14341 tagtaaccgg tgggatccag cctttatgcc atttggcaac agcatccctg acgatggttt 14401 cactgcctgt aacccccctg gccaccattt cccgccatat ccggccggag ttataattac 14461 cacattctcg ttgctctttt aaccactccc tccatgggtc cagaagccct cgctttggag 14521 gcctagttga catttcaggg aatgttcctg aacccaccca gcgactgact gtcactcgcg 14581 acaggcctgt aatacgggat atttccctga aactacatcc cttgttatgc agggccataa 14641 cctctgtcca acgctgatgc cgttttttgc ggatgtgctg tttaaggcgt tccagacgac 14701 ggagcgatgc tacaggcaca gatatttctg gctcaggtga tttcttcagt gataactctc 14761 tgacaacaag acgtatcaga ggcatatatc tgtacatcat tcgttcaggc tcatcaccaa 14821 tattttttag caggtgccat cgatcggcca cctgtctggc ctgaggtgca ccttcacgtg 14881 ctgctgtcgc atagactcca ctgcgatcac gcgagacaac ctgtatttcc ggatattttc 14941 tgaaccaggt cgccagcgta cgctgatcac ggccgggaag caggacgagg ggacggtgag 15001 tatcaggatt gactattaac ataccgcagc agtggccccg atgccacgcc cactcatcaa 15061 taccgacatg aggcgcgcct gactgtttcg tctccggggt attgataagc ctgcgaagaa 15121 gagtatcagc actgcaacgg agacccactg ccgttgcagc ccgttttcca gcctcacctc 15181 cagctattaa tcccagttga cgttgttaat tttgtaacgc ctgtgaagac tgctggtgtg 15241 aactggcgaa gggagcaagc gactcggcaa aaattttacg tgaacaagcc gggttacggc 15301 agtaccagtg gcggacggaa aatacaagcc atagcgtctg ccctgagcag ggtagatgct 15361 gtatccggcg ccgacgacaa ctatgaacag agtcgctacg cttaaagcat tcaggacatt 15421 gtgctgtttt gcgttttccg tggagatgga gggttatacc gtcagagcta ataatttgtc 15481 gactgcatcg ccatccgcaa ggtaactgta gaagtgtctt aagagagtgc attgcgttgc 15541 ccataactta aaacagctta gatccttgtt cgccagaaag tttcatccat tttcttccac 15601 ccaggttgcg gaagaaccac ttttcatccg tcgttgacag atgtgaagta tgcgggagaa 15661 aaagtgaata tctaactgta ataactcaga ccggtacgag tactcgggac gtctacaatc 15721 attcagggca aagtgctaaa atttctctat cccgggatgc ccctaccaac gcagcactcc 15781 cggagatatc attacagctc tgcaactgat ttccgcgact gaaccgctca gttcctatcc 15841 ttccagttgc cctcctgccc cccctccctg ctgtataccc cggtaccaca actcgggcag 15901 cacttttccc cctcataatt ttcgtcacac atcacacaaa accactttct caccttcacc 15961 gtataatccg gaaccgtcat accctgcaga tgcaaacgac gggcctcttt ctctgccggg 16021 tcaagccagg tgcatcgcag caggattttc tcagcgacag tcatctggtc atgttcaaac 16081 cacggtggtt gtccgtcatt gccccgctga agtgttaacg ggcatccaca ggacacacag 16141 cacaaaacgt cctggcggtt gtgcttcgct gcttctttcg ccgtaacaaa atggcctttg 16201 ctgtcattcg ccatataaca gttcagaatt cgcatatttc ctcctgagtt gtccggggaa 16261 tactgaatcc tccggtctgg cagtgtgtgc agtaccgctc cccataataa tcgtggtgac 16321 attgtctgca gtgccagctg gctttacgca ccacgggtaa ggcatccagt acgaattgct 16381 gcagacgttt aatcaactgt atttctctgc gctccggcct gacataaggg cactgttgac 16441 cgtgctctgt cagcctgtcg tcagtgtgtt caaaccaggg aagttcagtg tcgtattgcg 16501 gatggtatct gagtgcactg ccacacaagt ggcaggtgta gttagcataa ggtgcggcct 16561 gtgcagtacg ggcgcccgtc agacgtccgt tgccatcaag agcgataaag gattttgcgt 16621 acatagtcat attcctcagc cgccagacga cacgcaggca acagccgtcc cggtacgggc 16681 agcgtggtca gggtgtgaat ggcggttcag ttaaaatctg gactggagtt tgggtaaagc 16741 aggctggttg ctgttacagc actgtggttg tcacacaatg gaacactgac gtaaaaaaca 16801 gtcagtgggc gagtggatac atcgttgccg ccagacaaca acccatactt ttggtttgcc 16861 gggtattggc gcgccagtcg tgctcaactc cggctacagc caaaattgcg ctcaccggtg 16921 cagtgagctt tggtatgttc cttcgccaga tagtcagcac gttccagcac ctgctgaaag 16981 ccagtgtcat catcgcgttc cagccacacc gccggccagg ccggaaaatg caccagcgtg 17041 gcatggcacc cgacatccac tcccagggca ctgcaccacg cctgtttaat catcccggcc 17101 agtgatcccg gagcacggta atcaccggca cgacaccagg tatcccggtt aaccagcagc 17161 atcaggtgat agtgtttttt acctttgcac tccccaaact cccgggccca gacgtaatgc 17221 agggttgtgg gatgcacgcg tttaccttcc cgatgcttac gtttctggta agcgtcgatt 17281 cgggctttca gggcattgat gaagcgggat atcacagctg cgtccgttgc tgccggtaca 17341 tccgggaaac gcaggtcaac ccgcaatgcc gtcaggcggg gatgaacatt cagtgcgtgc 17401 cgcaccgtct cacgaatacg ttgctgccag aaggggttgt atttgtaggt catggttaaa 17461 tctccgtatg gttcatacgg aatagccacg tcgtaaaaaa tgcgcagagt ccctgaagtg 17521 acctccggca ggacactgtc tcaggcactc tgtgataacc cgaacggtcg tctccggact 17581 gacggttgaa ttttcagcgt tgttttttta atgtaaaaaa ccggttacgg gtaaggctgt 17641 gaggagggag tgatggtgat acgcaaaaag aagtgcaggg actgtggaaa cgcgattact 17701 cataatacag tgtgttgccc gtattgtggt tctgtcgacc ccttcggcta ttaccggaat 17761 acagaccgta tcgttaccat actgctggca ctgattattg tggtcctgct gactactgtc 17821 agcgtcagtg tgtatatact gtgtagctgg tgagataacg gttcatgtat cccctgagct 17881 gacagtgtac cgggtatatt aagcgtaacc gacaggttct ccttcatacc atattaaatt 17941 tttccaggta ttgccgctgc cttatttcgt cccatacagg aaaactcgtc tgggtttctg 18001 acaaatacgc gaaactcaca gcccctcaat atcaaccaca cgctgtaagc cggtaatacc 18061 tgaaaatcag cctattaccg cccgcgcctc cgttaccgaa cgctcaggtg accagactga 18121 agcccagcac gcactcgtaa aatttgcggt cagttccgtc agtcagtggg caaccgcaga 18181 gttacgggct tccaggtcca caggagtgag tctataacgc gtgtgggaaa tcattttttc 18241 tggcgttgac agaacgcctt acgggctgct acttacccgg tgtcccgcaa tacagcctta 18301 gtgttccgtt atcggggatc cggacgcacc gcaacaaccg gggaagtatt tctggtcaga 18361 gctgtgtcaa gagggatttc tcagcccctc actcaccggc tcagtctcag ggcagaagca 18421 ttaatacact cagttcatgt cttatacagg aatgggcata gggggagctg gcgtgtcact 18481 gctgatttta cgcatcagcg ttcatgtatc tgcactctga tacagaatgc ttcacagcgc 18541 tctgttac //