LOCUS NC_019757:2 17988 bp DNA linear BCT 16-MAR-2013 DEFINITION Cylindrospermum stagnale PCC 7417, complete genome. ACCESSION NC_019757 SOURCE Cylindrospermum stagnale PCC 7417, complete genome. COMMENT locus start: 1309766; locus end: 1327753 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.474244; n0_4mer:D = 26.063959; n0_4mer:PS = 37.513704 FEATURES Location/Qualifiers source 1..17988 /organism="Cylindrospermum stagnale PCC 7417, complete genome." gene -606..8 /gene="" /locus_tag="" /db_xref="1309159..1309773" CDS -606..8 /gene="" /product="hypothetical protein" /translation="MESNPYNILGVSPAASKAEITKALAAAMKRKQYPVDVIAKAQKS LMKSEERIIADYLRPILPPIKRWQYSDLSMLDRLAPTLVLLPEFDGLEQAIAQAIQEE RLEREPLPIPLAALLTEGITACQEGRYPKAIKYLEDYCQGCTEHDSKEYIQASTWLIK AYKMGGQLQRAIAICQLLTTHTHPQVQAWAKNNLLLLSKEISRV" gene 1..480 /gene="" /locus_tag="" /db_xref="1309766..1310245" CDS 1..480 /gene="" /product="molecular chaperone GrpE (heat shock protein)" /translation="VSDSSPTYILSQEQRDLLMQKLGNLQKENVLSQQSLREQQTQIA ANTEDLFLELLEVADALEALLDYLENHPDPSPEFIERLPRNIGAVNRKYLSVLGKRQV LPIELPGDQPDFNLCRVVDREIRTDVPDQTITKVVRRGFRLGEKILRPAEVVTSKSE" gene 701..862 /gene="" /locus_tag="" /db_xref="1310466..1310627" CDS 701..862 /gene="" /product="" /translation="LTEFNVINFNYWLIFSNLISPDPAKSVQYTGDNLTGVGDGDDII IKMNLEKKV" gene 1115..1687 /gene="" /locus_tag="" /db_xref="1310880..1311452" CDS 1115..1687 /gene="" /product="signal peptidase I" /translation="MTPHESDAKDATASSKIWRGWQENLTLIAIALCLAFLIRTLIAE PRYIPSESMFPTLHTGDRLVVEKISYRLHPPTFGDIIVFQPPAELQRRGYPKDQAFIK RIIGQPGEVISVAQGKVYLNGQALSENYIAEPPNQPFPPVKVPEGEFFVMGDNRNDSN DSRYWGFLPRKNIIGRAIFRFWPFDRIGLI" gene 1832..4132 /gene="" /locus_tag="" /db_xref="1311597..1313897" CDS 1832..4132 /gene="" /product="bacteriocin biosynthesis cyclodehydratase domain protein" /translation="MLNQPHFNPGYTVETIEPDEIFLLSEREAVWLSDRLSCRVAALL RDRHTIDEIIDIIQLELLQQQPTTQQTTDFFQNLLDVSIKTQYALFQMEQQGYLVEQD DSLPSHLAIFCHHLNITPTVATQRLQSATVAVKTLGSLPTDDFIAILKSQHIQIADAG DITIVLTDDYLHPQLEELNQQALKSQSPWMLVNPLGTMSWIGPIFHPHKTGCWQCLAQ RLRDNKPIERFIQKQKQISLSPPLGFLASTVQTALGMAATEVFKWIVQGENQRLEGNL ITYDTLTLQHQDHTLVKRPQCPSCGQMVNGLENQPLPVVLGHRKKNFTADGGHRYCSP QETFRKYQHHISPITGIVRELQKIPGSPLTHTYIAKHHFLNIFDDLDSLHQNIGGRSA GKGRTDSQARASGFCEAIERYSGVFQGNEITHKSSYQQMGNKAIHPNACMNFSPQQYQ NREQWNTQSKGWFQKVPEPFDIEREIDWTPVWSLTHQEFKYLPTAYCYYGYPQSHPPD CWADSNGCAAGNTLEEAILQGFMELVERDCVALWWYNRLPKTQVDLDSFNEPYFQNLK EYYQTLNRDLWVLDISSDLNIPAFAAISRRTDREVEDIVLGYGAHFDPKIAISRALTE VNQILPNVLRATEDGNTQYPPSADSLALDWWKSATLANQPYLLPDTQSVPKVSADYSQ LASDDLLEDVRLCQKIVEKNGLEMLVLDQTRPDIGLRVAKVIVPGMRHMWKRLGSGRL YEVPVKMGWLSEPLTEEQLNPYPMWM" gene 4180..5265 /gene="" /locus_tag="" /db_xref="1313945..1315030" CDS 4180..5265 /gene="" /product="putative TIM-barrel fold metal-dependent hydrolase" /translation="MLHGYKIIDADSHVIEPPQIWAKYLPPEFKHFAPSADMKIKGED ITQKISQQVRQQGNQQMMQAHPNAYLHRYDAESHLQAMVQMGVDIAFIYPTYGLWLFA IDTMPAEVVGAFTHAYNTWLYEEFCSYAPDKLKGVGAINLHAPEQMVSELHRIAEFGW KSVFLRPNPVKGRLLSDSAYEPFWTACEELGIAVGIHEGTHSRLPTTGADRFNTRFAL HACSHPMEQMMALLALIEGGVLERHPHLRVGFLESGCGWLPYWLWRMDQEYDNLHWEV QNHVKMKPSDYFRRQCFVAIDPSEPYLAQIIEYIGTDNLIFGSDYPHMDHQPDVVNMV LELETQLSQETVQKIVWDNTCRFYNLT" gene 5292..6356 /gene="" /locus_tag="" /db_xref="1315057..1316121" CDS 5292..6356 /gene="" /product="hypothetical protein" /translation="MSEKVTQTFQEPLKSWLDPKTYYQILLVTPPDPNTKKEGQNIQT KIVAKTKEEFDTYLTDKNNLDGSKETVGSHLPSPGVTLDDDFLKAIFSSESDCGKSVV MKPNQLDANNFYATSRNLLQSRKLSQLIANTWYCYVTAKESEAWKRFQNGDWHTDSHI LNGLIAREIFFISQSVYPSELEPENLDIYYPLRGRIAIPANGDKEHGKPRFLILPNST AWERIALSLLLAGQAYRQIKDDKSTTGYIYQQISQPIFSTGEIIHRYGLDVVWYDYIG KISEVQFSPVDVSTNYQVVIPYPPIPDEKNLSLEEIEKWAGASDKEAPFPFYRITEDN RYVGIDYVSPPYPYIPLSTS" gene 6408..6607 /gene="" /locus_tag="" /db_xref="1316173..1316372" gene 6642..7685 /gene="" /locus_tag="" /db_xref="1316407..1317450" CDS 6642..7685 /gene="" /product="hypothetical protein" /translation="VQILLKNLSFDLPISCNDPVLSKNTSRSGVEDNYYFQILTIEGK PGERVKKLVYGTRKNLVKYLEIADNELPTEGTKVNPEFVTKNDHQFCGVRFLLQGRQL SQIMSYTWLDDQKLQEYEPKDGTDPLKKVTKTQIELVREIFNSYNIIPDVYCLEDELT SSPTENIELCPLRNTELREKLFKAEEKNSKAEPYLIKPQYVSYNTISLSLLLSGQVYY QDEHEPDKWKQLWPSILSTYEMVWEYALDISWDTFYSSRVDIAQAGYPPTPPYTKVTL GYPPKPTEFSLTQENIQIWAEEVEELPEISEEENPNRRKFPFYPARNTEEWRSKNLQY VSPPFPYIPLSTT" gene 7846..13683 /gene="" /locus_tag="" /db_xref="1317611..1323448" CDS 7846..13683 /gene="" /product="putative ATPase" /translation="MIHNQDILQKDYQIIEKIYESASSLIYRAILKLNNQPIILKILK EDYPSPSELTRYKQEYEITSSLNADNIIKAYKLQRYKNSLVMLLEDFGGESLKILISK HQFSLEVFLTIAIKTTESLAAIHNANIIHKDINSANIVYNQETRQLKIIDFGISTRLS QENQIISNINQLEGTLAYISPEQTGRMNRGIDYRSDFYSLGVTFYELLTNQLPFTTND PIELVHCHIAQHPKIPNELIASIPLTLSNIIIKLLAKTPEERYQSAWGIKADLETCLQ QLKTTGNIGHFSLGSQDISDKFHIPQKLYGREQEITQLLTTFERVSQGKAEIILVSGY SGIGKSALVNEIHKPITKQRGFFINGKFDQLQRDIPYAAITQAWQGLVRQLLSEPEIT LKTWKEKILAVLGNNSQIIIDIIPDLEKIIGKQPPVEQLGATETQDRFNLFFARFVHI FSQKEHPLTIFLDDLQWADLPSLNLIEKLITNVDSQYLLIIGAYRNNEVSPTHPLTQT LEQIKKAEVIINQIMLQPLGISDVKQLMADTLNCSREDVQPLAELVTKKTAGNSFFIT QLLQTLYKEKLLVLNVPQLPIHQRENNQGFWQWNIEKIQQIGITDNVVDLVVRKIEKL EQNTQNILKLAACIGNRFNLEILSIVNRKSLTFTSQEIQPALQEGLIIPLSNDYKLPL LWSEEEISGDTSEISSDFILKNSTSIPYKFLHDRVQQAAYSLILEAEKKSIHLQIGRL LRNNTPADELEENIFNIVHQLNEGLSLITEPLEKYELAKLNLQAAKKSKASTAYEPAL KYLEMGLSLLGSNSWNEQYTLTWELHIETLELLYLNTKFDQFEEFSNTVLQQAQEILD QAKINQLQILYYCTTFQANKAIDIAIKISRKLGTHISQEQGDIENKIAQQQDLIQLFL QDKNLEYLYQLPVMTDKYQIAIVQILQQIIAATHTTNFPLFVEIILIQLNLCIKYGNP PNAAYIYNTYGMLLCSIKQDIDYGYQFGNLALKLVEKSKIKKLEVFVLQMYYGQIWHW KEYLRNIVAQNKLIYGFKIGIDTGGNEFASYVAINYCLIKFFGGQNLEEVEQDYQKYS GVIKNLKLQFSIFIMETFHKLIIKFLGINNYDKLIISDNVEQEYLENWIQNNSQWLIF FFYFTRTFYCYLLKDYACACANGIKAEKYVEASSSFLTAPQHNFYSSLSYLAHYSACD IKQQQNLIEQVDKNQESMKIWSNHCPENFQHKYDLVAAEKARALVQYWQAEDLYERAI QGAKKYEFIHEEALAYERAAEFYLHLGREEIGQLYLRNAHHCYTRWGAKAKVKQLEDE YPEYFIGNTNQGTAKSLSTTISTSGSNGEFLDLTTVIKASQALAGEIVLNKLLAKLMK IMIENAGARKGFLLLHSDDNWVIEAVGAIDSDDVTILQSIPVDSPDASTPLLSTAIIN YVARTQENVVLNDATQEGQFTRDPYIVITQPKSILCTPLLNQGKLSGILYLENNLATG AFTPERVEVLNILSSQAAISIKNSRLYATLEQKVEKRTQELSQTLEILKETQAKLEFE NALLKSAEEASIYDYQVGGSLPIDAPTYVVRSADRYLYKALKSGEFCYILNTRQMGKS SLMVRMMHYLQQESFCCAAIDMTRIGSENITPEQWYKGLAVELWQGFDLLGKVNLKAW WQENIELSPVQRLSRFFEEVLLGEVKLPDNTLAPKIVIFLDEIDSVLGLDFSVNDFFA LVRSCYNQRGINPEYQRLCFVLLGVATPSDLITDYRRTPFNIGQAIQLHGFQLHEAQP LLQGLSDKVSNPQAVLQEVLFWTNGQPFLTQKICKLIRSLSSSVPEKTEKAWIKNLIC TNIIDNWETQDEPEHLRTICDRILKGERQATDLLELYRRILEQGQVRAVDSLDERELI LSGLLVKEQSYLKIHNRIYELIFNNSWIELQASLNRNMNGADPAN" gene 14065..14607 /gene="" /locus_tag="" /db_xref="1323830..1324372" CDS 14065..14607 /gene="" /product="lactoylglutathione lyase-like lyase" /translation="MPQVLEKITRSFIKPALCLLLVFGCLFGFTAGSEAAAVETNALV QVNPPGGIQSLLSSLNVSNLQNSIDFYQNKLGLIRNTKFDTDDWTQFFVIGKESISQI SPATPQIGLYQGSVKSDSTSVPTIIVNDIEQYRDYLLDNGIKVGGIIPIEVAGGKVGL KLAFFTDPDGNKLTIRQNLI" gene 15399..16814 /gene="" /locus_tag="" /db_xref="1325164..1326579" CDS 15399..16814 /gene="" /product="hypothetical protein" /translation="MAFHLDEAIKIANQAVSAKFYRSLTDVEIIVLKGAWEREEYDQI AAKNQYATSYISQDIAPKLWKLLTEALGEKVKKSNFKEALKRHWEKECWDRQFTSEYY LPNPESITVKGKQGNNTLKEAASPTYLTQAKQNFPAPELYVERFAIELLCYETLLQPG SLIRVKAPKLMGKTSLMERVLAKVAKEGYRTVSLSLEMADRQTHLTNLNKFLRWFCLN LSRELKLRNQLDEYWDEEGMGAKVSCTTYLEEYLLAAADSPLVLYLDDVDALFPYPEV YEDFFGLLRSWYEKARSRANWKKLRLAIAHSTDVYIRLNINQSPFNVGLPIELPELTK EQVQEFAQLYGLAADSSSVDPLMQLVGGHPYLLQQAFSHLKSYPDITLEQMLAEARTD AGIYRHHLRQFWLSLQQEPKLMAAFETVISSTEPVRLETISAYQLQSMGLVKLAGNEV EPRCQLYRSYFSDVIGSSEGV" gene complement(16990..17571) /gene="" /locus_tag="" /db_xref="1326755..1327336" CDS complement(16990..17571) /gene="" /product="hypothetical protein" /translation="MKIFKQLPQIFSGKALKMSTYCKIAIAYAGRFAIALLAIFLWVV PTTSTFAATNSLSQEIVPAATVQFPTENITLRLLDLGESNNLLADASDYDPQISNTEE GLASIFQNFAEAWKKPNKKESLFNVCENTVLDRKTCFVLLISDIKQKKKDLINACYKP GINGKLCLDLALRQLGVNMETLNAWIAELDAIS" gene complement(17743..17988) /gene="" /locus_tag="" /db_xref="1327508..1327753" CDS complement(17743..17988) /gene="" /product="hypothetical protein" /translation="MKLPIQVVPVQRNLSIATYAMSSGIQASVFNPCACHAKGLGCIV TRNDCPAGWMPRCEVQLGAGCVCYCCSATGTCSGPYE" ORIGIN 1 gtgtctgact catccccaac ctatattctc agccaagaac agcgtgactt gctaatgcaa 61 aaacttggta atctgcaaaa agaaaatgtt ttatcacaac agtccttgcg agaacagcaa 121 acccaaattg ccgcaaatac cgaagattta tttttggaac ttttagaagt tgctgatgcc 181 ctggaagccc tgttagacta tctggaaaat caccccgacc ccagtccaga atttatcgag 241 cgcttaccca ggaacatcgg cgcagtaaat cgtaaatacc tcagcgtact aggaaagcgc 301 caagtcttgc ctatagaatt gccaggtgat cagccagatt ttaacttgtg tcgcgtagtt 361 gatcgagaaa tccgcaccga tgtcccagac caaacaatta ctaaagttgt ccgtcgcggg 421 tttcgtttag gtgagaaaat cctgcgccca gcagaagtag ttacatctaa atcagaataa 481 gcaccgttga tagtttctat ggctagaagt cattggcttt gcgcctgact ttccagtcaa 541 aaatcaagtt acttaactta agtagatacc tgtagtatat ttaaatactt tatattacaa 601 tggcgagaaa ataccagcaa tgaagtacgt aaaaatacta taggcaaata ctgaagacaa 661 gtatttaagt taatttttat attcttttgt caaaaaataa ttgacagaat ttaacgtcat 721 aaattttaac tattggttaa tcttttctaa cctcatcagc ccagatccag ctaagtcagt 781 tcaatacaca ggagataatc tcacaggcgt tggcgatggc gatgatatca ttatcaagat 841 gaatcttgag aaaaaagtgt aatcactttg ggattatttg agactgcata ttgttattgc 901 ctaaatttat ctttaattac ttaatgccta tcaggtttgt caagggaacc tagataggct 961 atttcttttg aaaattaaat gggcgaatat gctgagtaat gacaataacc acaacaagtt 1021 taaattacgg cttgataact ataagatgcg ataatcagat cattgatatt tgtattgtct 1081 gggtttgcac tgtttaaact ggctgaaaac ttctatgact cctcacgaaa gtgatgcaaa 1141 agatgctacc gcgtcatcaa aaatatggcg cggttggcaa gaaaatctca ccttaattgc 1201 gatcgcctta tgtttggcat tcctgatccg cactttgatc gctgaacccc gctatatccc 1261 ctctgagtcc atgtttccca ccttacacac aggcgatcgc ctagtggtgg aaaaaatctc 1321 ctatcgtctt cacccgccca catttggaga tattattgtt tttcagccac ccgcagaatt 1381 acaacgccgg ggatatccca aagaccaagc cttcatcaag cggattattg gtcagccagg 1441 agaggtaatt agcgttgctc aaggaaaagt ttatctcaac ggtcaagctt tgtcagaaaa 1501 ctacatcgct gaaccaccta atcagccgtt cccaccagtc aaagtcccgg aaggtgaatt 1561 ttttgtgatg ggagacaacc gcaatgatag taatgactcg cgctactggg gctttttacc 1621 gagaaaaaat attatcggtc gagcgatatt tcgcttctgg cctttcgacc gcatcggctt 1681 aatataaact gctccaacct acttcgcttt tgcgtccttt gcggtaatgc cgagcgctcc 1741 cgtaaaggat aggtttcttc atgatttcgc ataagtcctg aatttttaat tgtttaatgt 1801 ttcagcgtca attcattaaa aaataaaaac tatgctcaat caaccacatt tcaaccctgg 1861 ttacaccgtt gaaaccatag aaccagatga gatatttctc ttatccgaga gggaagcagt 1921 gtggttgagc gatcgccttt cttgtcgtgt agcggcttta ctgcgcgatc gccataccat 1981 agacgaaatt atagacataa tccaactcga actactccaa caacaaccca ccacccaaca 2041 aacaaccgac ttcttccaaa atctgctcga tgtcagcatc aagacccaat atgctctatt 2101 ccaaatggaa caacagggct atctggtaga acaagatgac tcactaccct cccacctagc 2161 catcttctgt catcatctca atattactcc cacagtcgct actcaacgat tacaatcagc 2221 cacagtcgca gtcaaaacac taggttccct tcctaccgac gacttcatag ccatcctcaa 2281 atcccagcat attcaaatag ctgatgcagg agatatcaca atagtcttga cagacgacta 2341 cctccacccc cagctagaag aacttaatca acaagcatta aagtcacaat ctccctggat 2401 gctagtcaac cccttgggaa caatgtcctg gatagggcct atatttcatc cccacaaaac 2461 aggatgttgg caatgtctag cacaacgttt acgagataac aaacccattg aaagatttat 2521 ccaaaagcaa aagcagattt ccttatctcc tcctttaggg ttcctagctt caacagtgca 2581 aacagccctc ggaatggcag ctacagaagt cttcaagtgg attgtccaag gggagaatca 2641 acgattagaa ggtaatttaa tcacatacga tacactgact cttcagcatc aagaccatac 2701 tcttgttaaa cgtccccaat gtcccagttg tggacagatg gttaatggat tagagaatca 2761 gcccctaccc gttgttttag gacaccgcaa gaaaaacttt accgcagacg gaggacatcg 2821 ttattgttcc ccccaagaaa cttttagaaa ataccaacat catattagtc cgattacagg 2881 cattgtccga gaactgcaaa aaatcccagg aagtccttta acgcatacat atattgccaa 2941 gcatcatttc ctcaacatct ttgacgattt agacagctta caccaaaata tcggcggtag 3001 aagtgcaggc aaaggtagaa cagatagcca agccagagcc agcggtttct gtgaagccat 3061 tgaaaggtat tctggcgtat ttcagggaaa tgaaataaca cataaaagca gttatcaaca 3121 aatggggaac aaagcaattc accccaatgc ctgtatgaac ttcagcccac agcaatacca 3181 gaatcgagaa caatggaata cccaatctaa aggttggttt caaaaagtcc cagaaccctt 3241 tgatatagaa agagaaatcg actggacacc agtttggtct ttaacccacc aagaattcaa 3301 atatctgcca acagcttact gctattatgg ctatccccaa tctcatccac cagactgttg 3361 ggcagactcc aatggatgtg ccgcaggtaa caccctcgaa gaagctattc tccaaggatt 3421 tatggaatta gttgaacggg actgtgtagc attatggtgg tataaccgtc tgccaaaaac 3481 tcaagtagat ttagacagtt tcaatgagcc ttactttcaa aacctcaaag aatattacca 3541 aacccttaac agagacttgt gggtattaga tattagcagc gacctgaata ttcccgcttt 3601 cgctgctatt agtcgccgaa cagatcgaga agtagaagat attgttttag ggtatggtgc 3661 ccactttgac ccaaaaattg ccattagtcg agccttaacc gaggttaacc aaattctacc 3721 taatgtactc agagctacag aggatggtaa cactcaatat cccccatctg ccgattccct 3781 agctctagat tggtggaagt ctgcaacttt ggccaatcaa ccttatctgc ttcctgatac 3841 tcagagtgtc cccaaagtta gtgctgatta ttcacaacta gcaagtgacg atctacttga 3901 agatgttaga ctttgtcaaa aaatcgtcga gaaaaatgga ctggaaatgc tagtgttaga 3961 tcagacacgt cctgatattg gactgagagt agccaaagta atagtaccgg gaatgcgcca 4021 tatgtggaaa cgcttaggtt caggacggct ttatgaagtt ccagtgaaaa tgggttggtt 4081 gtcagagcct ctgacagaag aacaactcaa cccttatccc atgtggatgt aattgacact 4141 tgtaaatcgg ttaatcccag aaattacaca gctttaacta tgctgcatgg atataaaatt 4201 attgatgctg attcccatgt aatagagcct ccgcagatat gggccaaata ccttccccct 4261 gaatttaagc actttgcacc ctcagcagac atgaaaatca aaggggaaga cattacgcaa 4321 aaaatatccc agcaagtgcg acaacaaggc aatcagcaga tgatgcaggc tcacccgaat 4381 gcttatcttc atcgctacga tgcagaatct cacctccaag caatggtaca gatgggggtt 4441 gatatagcct ttatttatcc aacttacggt ttgtggctct ttgccattga taccatgcca 4501 gcagaagttg taggagcctt cacccatgcc tacaatactt ggttatatga agaattttgt 4561 agctatgctc cagacaagtt gaaaggagta ggagcgatta atcttcatgc accagagcaa 4621 atggtgtcag aattacaccg catcgccgag tttggctgga aatcggtatt tttacgccct 4681 aaccccgtta aagggcgact cttaagtgat agtgcctatg agccattttg gacagcctgc 4741 gaagagttag gtatagcagt cggaattcat gaaggcaccc atagccgctt accaactaca 4801 ggtgcagata gatttaatac tcggtttgcc ctgcacgctt gttcccatcc aatggaacag 4861 atgatggcat tgttagccct gattgaagga ggggtattag aacgtcatcc ccatctcagg 4921 gtagggtttc tagagtctgg ttgtggttgg ctcccttact ggctctggcg aatggatcaa 4981 gagtatgata atttacattg ggaggtgcaa aatcatgtta aaatgaagcc atcagactac 5041 ttccgtcgtc agtgctttgt agcaattgac ccttctgaac cttatttagc ccaaattatc 5101 gagtacatcg gtactgataa cttaatcttc ggctctgatt atcctcacat ggatcatcag 5161 ccggatgttg tcaatatggt tttagagctt gagacgcagt tatctcaaga aacggtgcaa 5221 aagattgttt gggataatac ctgccgtttt tacaatttga cttgaaactt acataaggac 5281 gcactactat catgagtgaa aaagtaacac aaacatttca ggagccacta aaatcgtggc 5341 ttgatcctaa gacatattat caaatccttc tagttactcc ccctgatccg aatactaaaa 5401 aagaaggaca aaatatacaa acaaaaatag tagctaaaac caaggaagaa tttgacacct 5461 atctgactga taagaataat cttgatggtt ctaaggaaac ggtaggttcg catttaccct 5521 cacctggggt aactctagac gatgattttc tgaaagcaat tttctcatct gagtcagatt 5581 gtgggaaatc cgtcgtaatg aaaccaaatc aactagatgc taataatttt tatgctacaa 5641 gccggaatct attacagagc cgcaaactat ctcagctaat tgctaacaca tggtactgct 5701 atgtaacagc aaaagaatca gaagcatgga agcgttttca aaatggtgat tggcatacag 5761 attctcacat attaaatgga ctcatagcta gagagatttt ctttatttct caaagcgttt 5821 acccatctga gcttgaaccc gaaaatcttg atatttatta tccactcagg ggtagaatcg 5881 caattcctgc aaatggtgat aaagaacatg gaaaaccaag attcttgatt ttgcccaata 5941 gcacagcttg ggagagaatt gctttgagcc ttttattagc aggacaggca tatcgccaaa 6001 ttaaagacga taaatcaact actggttata tttatcaaca aatttctcag cctattttta 6061 gtacaggtga aataattcat aggtatgggc tagacgtggt atggtacgac tatataggta 6121 agatcagcga agtacaattt agtccagtag atgtttctac taattatcaa gttgttattc 6181 cttatcctcc aataccggat gaaaaaaatc tatctcttga agaaattgaa aaatgggctg 6241 gagcttctga taaagaagca ccatttccct tctatcgcat aacagaggac aacagatatg 6301 taggtataga ttatgtttca cctccatacc cctacatacc gctatctact agttagaaca 6361 actgggagta aacaggaagt cactagtata atgtactccc aaattagtta gggatagacc 6421 cgaatgaacc ttattaagcc ccatcgagta cattggtgct gataacttaa tcttcggctc 6481 tgactaccct cacatggatc acaattctga catcgttgat aaattagtcc ttgaagagca 6541 tttatcaaga acaattgtca aaaagattgc tggggataat ccccagcgtt tttataacct 6601 ggtctaatca ttctattctc taattgcaaa ggaagcagaa agtgcaaata cttttgaaaa 6661 atttatcttt tgatttacct atttcctgta acgatccggt gttgagtaaa aatacatctc 6721 gatctggggt tgaagataac tattactttc aaatactcac gatagaagga aagccgggtg 6781 agagggtaaa aaagttagta tatggaacta gaaaaaattt agttaagtac ctggaaattg 6841 cagacaatga gttgcctaca gaaggaacaa aagttaatcc ggagtttgta acaaaaaatg 6901 atcaccaatt ttgtggagta aggtttctat tacaaggtcg ccagctgtct caaataatgt 6961 cttatacatg gcttgacgat cagaagcttc aagaatacga accaaaagac ggaacagacc 7021 cactgaaaaa agtaacaaaa acacagatag agttagttag agaaatattt aattcgtata 7081 acattatccc tgatgtttat tgtttagagg atgaattaac atcatcccct acagaaaaca 7141 ttgaactatg ccctttgaga aacacagaac ttagagaaaa gctattcaaa gctgaagaaa 7201 aaaatagcaa agctgaacct tacttaatta aaccccaata tgtaagttat aacacaatat 7261 ctctatctct attattaagc ggacaagtat attatcaaga tgaacatgag ccagataaat 7321 ggaaacagct ttggccatcc attctcagca catatgaaat ggtttgggag tatgcattag 7381 acatatcatg ggatacattc tattctagta gagttgatat tgctcaagct ggttatccac 7441 caacacctcc ttatactaag gtaactctgg gttatcctcc gaaaccgact gaattcagtc 7501 tgacacaaga aaatatccaa atatgggctg aagaagttga ggaattaccg gaaatctcag 7561 aagaagagaa tccaaataga agaaaattcc ccttttatcc tgcaagaaat actgaagaat 7621 ggcgtagcaa aaacttacaa tatgtctctc ctcctttccc ctatattccc ctcagtacta 7681 cttaagtaaa cttacttaat tgattgcctt gttgactcat tttctgagta ggtaaactac 7741 aaatacagta tctataagca ggttggttga atttcaccaa tctgcttacg tatgttattt 7801 aataaataaa aagcatactt cctaaaccag actcccaatt ctaatatgat tcacaatcaa 7861 gatattcttc aaaaagacta ccagattatt gaaaaaatat atgaaagtgc tagttcattg 7921 atctatcgag ccattctcaa gcttaataat caacccatta ttctgaagat tcttaaggaa 7981 gattatccca gcccctcaga actcacccga tataaacagg aatatgaaat tacaagttcc 8041 ttaaacgcag ataacattat taaagcctac aaattacagc gatataaaaa tagtttagta 8101 atgctgttgg aagactttgg cggtgaatct ttaaaaattt taatatccaa acatcaattt 8161 agcttagaag tatttctgac cattgctatc aagaccactg agagtttagc agctattcac 8221 aacgctaata ttattcacaa agacattaac tctgccaaca ttgtctataa ccaagaaact 8281 agacaactga aaataattga ctttggtatt tctactcgtt tatctcaaga aaatcagatt 8341 attagcaata tcaatcaatt agaaggaaca ttagcttata tttctccaga acaaactggt 8401 agaatgaacc ggggtataga ttaccggagt gatttttatt ctttaggtgt cactttctat 8461 gaactattaa caaatcaact tccatttact accaatgacc ccatagaatt agtccattgt 8521 catatcgcac aacacccaaa aataccaaat gaactgattg cttcaattcc tttaacatta 8581 tctaatatca ttatcaaatt gttagcaaaa accccagagg aaagatatca aagtgcttgg 8641 ggaattaaag cagatttaga aacttgtctc cagcaattaa aaactacagg aaacattggt 8701 catttttctt taggatctca ggatatttct gataagtttc atattccaca aaaactctat 8761 ggacgagagc aggaaattac tcaactgtta actacttttg agcgagttag ccaaggtaaa 8821 gcggaaataa ttctggtttc tggttattca ggtatcggta aatctgcctt agttaatgaa 8881 attcataaac caattacaaa acaaagagga ttctttatca atggtaaatt tgaccagtta 8941 caacgagata ttccttatgc agcaataacc caagcttggc aaggtttagt ccgtcaactc 9001 ttgagtgaac cggaaatcac cctaaaaact tggaaagaaa aaattttagc agttttagga 9061 aataatagtc aaataattat tgatatcatt cctgacttag aaaagattat cggtaaacag 9121 ccaccagttg agcaactagg agcaacggaa acacaagata gatttaactt attttttgcc 9181 agatttgtcc acattttcag tcaaaaagaa caccccttaa caatctttct cgatgactta 9241 caatgggctg atttaccatc tttgaattta attgaaaaac taattaccaa tgttgacagc 9301 caatatttat tgattatagg ggcataccga aataatgaag tcagtcctac ccatccttta 9361 acgcaaacat tagagcaaat taaaaaagct gaagttataa ttaatcaaat tatgcttcaa 9421 cctttgggaa ttagcgatgt taaacaatta atggctgata ccctaaattg ctctagagaa 9481 gatgtacaac ctttagcaga gttagtcact aaaaaaactg ctggtaattc tttctttatc 9541 actcaattac tccaaacatt gtataaagaa aaactattag tgttgaatgt tcctcaactc 9601 cccattcatc aaagagaaaa taatcagggt ttttggcagt ggaatattga gaaaattcaa 9661 caaataggta taactgataa tgtagttgac ttggtggtca gaaagattga aaaactagag 9721 caaaatacac aaaatatttt aaaattagct gcttgtatag gcaacagatt taatttagaa 9781 attctgtcca ttgtcaatag aaaatcactg actttcactt ctcaggaaat acagccagca 9841 cttcaggagg gtttgattat tcccctaagc aatgactata aattaccctt gctatggagt 9901 gaagaagaaa tatcaggtga tacttcagaa atttcctcgg acttcatcct caaaaattcc 9961 acatctattc cctataaatt tttacatgat cgagtacaac aagcggctta cagtctgatt 10021 ttagaagcag agaaaaaatc tattcatttg caaataggcc gtttgttgag gaacaatact 10081 ccagcagatg aattagagga aaatattttt aatattgttc atcaacttaa cgaaggatta 10141 agtttaatta ctgagccatt agaaaaatat gagttagcta aattgaatct tcaagcagct 10201 aaaaaatcta aagcctcgac agcttatgaa cccgctctta aatatttaga aatgggatta 10261 agtctcttag gatcaaatag ctggaatgag caatatacat tgacatggga attgcatata 10321 gaaactttag agttgcttta cttaaacact aaatttgatc aatttgaaga gttttctaat 10381 actgttctgc aacaagccca agaaattctt gatcaagcaa aaattaatca gctacaaata 10441 ttatactatt gtacgacatt tcaagctaat aaagcaatag acattgctat taaaatttca 10501 agaaagttgg gaacacatat ttctcaagaa cagggcgata tagaaaataa aattgcacaa 10561 caacaagact taatacaatt atttttacag gataaaaacc ttgaatattt atatcaatta 10621 cctgtaatga ccgataagta tcaaatagcg atagtacaaa tactacaaca aattattgca 10681 gctacacata cgacaaactt ccctttattt gttgaaataa tattgattca gcttaatctt 10741 tgtataaaat atggaaatcc acctaatgct gcttatatat ataatactta tggaatgctt 10801 ttgtgtagca taaaacaaga tattgattat ggatatcagt ttggcaattt ggctctcaag 10861 ctagtagaaa aatctaaaat taaaaaatta gaagtttttg ttttacaaat gtattatgga 10921 cagatatggc attggaaaga gtatctcagg aatatagttg cacaaaataa attaatatat 10981 ggctttaaaa taggcataga tactggagga aatgagtttg cttcttatgt agctataaat 11041 tattgcttga tcaagttttt cgggggacaa aatttagaag aagttgagca ggattaccaa 11101 aaatattctg gggttattaa aaacttaaaa ctacaatttt ctatatttat tatggaaacg 11161 tttcataaat taataattaa atttttaggt ataaataatt atgataaatt aataattagt 11221 gataacgtag aacaagaata tttagaaaat tggattcaga ataatagtca atggttaatc 11281 ttttttttct attttaccag aacattttat tgttatcttt taaaagatta tgcttgtgct 11341 tgtgctaatg gaattaaggc agaaaaatat gtagaagctt ctagttcatt tctaactgct 11401 ccccagcata atttttattc ttctctttct tatcttgctc attatagtgc ttgtgatatc 11461 aagcagcaac aaaatttaat tgagcaagta gataaaaatc aagagagcat gaaaatatgg 11521 tctaaccatt gtccagaaaa ttttcaacat aaatatgatt tagtggcggc tgaaaaagca 11581 cgagcattag tccaatattg gcaagcggaa gacctttatg aacgagctat tcaaggggct 11641 aaaaaatatg aatttatcca cgaagaagct ctagcttatg aacgagcagc agaattttat 11701 ttgcacctgg gtagggaaga aattggccag ttatatctga gaaatgccca ccattgttac 11761 actcgctggg gagctaaagc caaagtcaag caattagaag atgaatatcc agaatatttt 11821 ataggaaata caaaccaagg gacagctaaa agcctcagca caactatctc tactagcggt 11881 agtaatggag aattccttga cttaacaacg gttattaaag catctcaagc cctagccgga 11941 gaaattgttc tgaacaagtt gctggcaaag ttaatgaaaa taatgattga gaatgcaggc 12001 gctcgaaaag gctttttgct tctacattct gatgataact gggtcattga agcagtggga 12061 gcaatagatt ctgatgatgt taccatacta caatctattc cagtagactc accagatgcc 12121 tccaccccgt tgctctcaac cgctatcatc aactatgtcg cccgcaccca ggaaaatgta 12181 gttctcaatg atgccaccca ggagggacaa tttacccgcg acccctacat tgtcatcact 12241 caacctaaat caattctctg cactccccta ctgaatcaag ggaaattgag cggtatttta 12301 tatttagaaa ataatctcgc aactggggca tttacaccag agcgagtgga agtcttaaat 12361 atcctttcta gtcaagccgc tatctctatt aaaaattctc gcctctacgc aaccctggag 12421 caaaaagtag aaaagcgtac tcaagaacta tcacagactc tagaaattct taaagaaact 12481 caagctaaat tggaatttga gaatgcgctg ctcaaaagtg ccgaagaagc ctcaatttat 12541 gattatcaag ttggcggtag tttgccaatt gatgctccta cttatgtagt gcgctctgcc 12601 gaccgttatc tctacaaagc attgaagagt ggagagtttt gttacattct caatacacga 12661 caaatgggta aatcaagttt gatggtgcgg atgatgcact acttacaaca agaaagtttt 12721 tgctgtgctg ccattgatat gacccgaatt ggcagtgaaa acattacccc agaacaatgg 12781 tataagggat tagctgttga gttgtggcaa ggttttgacc tgctaggtaa ggttaattta 12841 aaagcttggt ggcaagaaaa tatcgaactt tcccctgtgc agcgattgag tagatttttt 12901 gaagaagttt tgttaggcga agttaaattg ccggataata ctcttgcacc taaaatagtc 12961 atctttttag atgaaattga tagtgtttta ggtttggact tttcagttaa tgatttcttt 13021 gccctggttc gctcctgcta taatcagcgc ggtattaatc cagagtatca gcggttgtgc 13081 tttgttttat tgggagttgc tactccgagt gatttaatta cagattatcg ccgtacgcct 13141 tttaatattg gtcaggcaat tcaactgcat ggcttccaat tacacgaagc tcaacctctg 13201 cttcaaggtt tatcagacaa ggtgagcaac ccacaagcag tgcttcaaga agtattgttc 13261 tggactaacg gtcagccgtt tttaactcaa aagatttgca agctgattcg tagtttatca 13321 tcttctgtcc ccgaaaaaac tgaaaaagcc tggattaaga atttgatttg cactaatatt 13381 atagacaact gggaaactca ggacgaacca gagcatttaa ggacaatttg cgatcgcatc 13441 ctcaaaggag aacgacaagc tactgatctg ctggaactgt atcgacgaat tttagagcaa 13501 ggacaggtga gggcagtaga tagtctggat gaacgagaat tgatattatc agggttatta 13561 gttaaagaac agagttattt aaaaatccac aaccggattt atgaattaat ttttaacaat 13621 agttggattg agctacaggc gtcgctgaat cgaaatatga atggtgcaga tcctgcgaat 13681 tagggttcta ccgctccctt gatgtaaaat ctggttcaca atcattgaaa gctttatact 13741 gtaggcattt cacttaatac aatgctaatg ggatcactgt tgttcgcatt caggcaattg 13801 aagttaccct gacctcgcca aatgcgaaat ttgtcaggct gtagacatta tgagtcaaca 13861 ggatcgcatc tgtcaattca aaggttgtat tacgggcaaa ctccagtatg tgctctatca 13921 aacacttttg accacaacca cctgaattta gctgaattta gctgaattta gctgaaattt 13981 aaaaatcctg aatttagctg aacttttaat gtgtgaaagc aaaatatatt atcaatgtac 14041 aagcacaaat gctaggagaa ttttatgcct caggtcttgg aaaaaatcac tcgttctttt 14101 attaaacctg ccttgtgttt actgttagtt tttggttgtc tgtttggttt tactgctgga 14161 agcgaagctg ctgctgttga aaccaatgca ttagtccaag tcaatccccc tggcggaata 14221 cagagccttt tatctagctt aaacgtatct aatcttcaaa attccatcga cttctatcag 14281 aacaaacttg ggttaatacg taacacaaaa tttgataccg atgattggac tcagtttttc 14341 gtcataggca aagaatcaat tagccagata tccccagcaa cacctcaaat tgggctttac 14401 caaggtagcg taaaaagtga cagtacatct gttcctacaa tcattgtaaa tgacatagaa 14461 caatatcgtg actacctgct agacaatggc atcaaagtag ggggtattat acctattgaa 14521 gttgcagggg ggaaggtagg actgaaatta gcgttcttta ctgacccaga tggtaacaaa 14581 ttgactatta gacaaaacct gatttaagaa aaattactta gacattcttc ttgaaattcg 14641 ctttgtcagt gaaaggtgct gaatctggta attaagacaa attattacct tgttccaatc 14701 ccctaatttt aattagggga tttctattta aaattccgaa tcttgcaatt tgctaccaca 14761 catagctaaa atacttatta catcagtctt tcagcatact tcgtcgcccc atcagttcca 14821 tctgatgctg tatgcgatcg cctccaagat accaaactag ataccaatga acatgaaatg 14881 gatgttttta ctttaattat caaatttcga cacctactta cttgttgatt atttttaatt 14941 gctgcttatt gagaaacgag tataccgatt tttaagcata tgcaaataat tttaaacttt 15001 ttataccaaa aattacgaga gtcctatttg agttgtgaac ttactcatgg atgcaaaaga 15061 aatctttaca gggaacggga aacagaattt tctcgaaatt acttagaagc aaatagtata 15121 attgaagcta gaaatatacg attattttaa gtaataaccc tcagtgacac tttatggtgc 15181 gggatgtgac ttaaaaatct ataactgtgt ttataaatta atttttaata ggagttagat 15241 tttacgtcat acatgatatt ctcagtaata aataaccaaa tttttcaaat gagcgataaa 15301 tatttacctt tacttggaga aaagcccttg aacgtaaaac cggggtgcaa gttaatcaaa 15361 caactcagga taaataaaag ctttcactct agctcattat ggcttttcac ttagatgagg 15421 caattaaaat tgctaaccaa gcagtttcgg caaagttcta tagaagctta actgatgttg 15481 agataattgt acttaaagga gcttgggaac gagaagaata tgaccaaatt gcagctaaaa 15541 accagtacgc aacaagttat atcagtcaag atattgcgcc caagctttgg aaattactga 15601 cagaagctct aggagaaaaa gttaaaaaaa gtaattttaa ggaagccttg aaacgacatt 15661 gggaaaagga atgttgggat aggcaattta catctgaata ttacttaccc aacccagaat 15721 caataactgt taaaggcaaa cagggtaata atacccttaa agaagctgca tctccgacct 15781 atttaactca agctaaacaa aattttccgg ctcccgaatt gtatgtggag cgttttgcta 15841 ttgaattgct ctgctatgaa actctgttgc aacctggttc cctgattcgg gtcaaagcac 15901 ctaaattaat gggtaaaacc tcgctcatgg aacgggtatt agctaaagtg gcaaaggagg 15961 gctatcgtac agtcagttta agtttagaga tggcagatcg gcaaactcat ctcactaacc 16021 tgaataaatt tttacgctgg ttctgcctca atcttagccg agaacttaag ctacgcaatc 16081 agttagatga atattgggat gaagaaggta tgggtgctaa ggtaagttgc acaacttatt 16141 tagaagaata cctcttggca gcagcagata gtcctctagt tctatactta gatgatgtgg 16201 atgcactttt cccttatcct gaagtttacg aagacttttt tgggttgttg cgttcttggt 16261 atgagaaagc cagaagccgc gcaaactgga aaaagctgcg attagcgatc gcacattcca 16321 ccgacgttta tatccgcctg aatatcaatc agtcaccctt taatgtggga ttacccatag 16381 aattaccaga attaactaaa gagcaagtgc aggaatttgc acaactatat ggattagcag 16441 cagattcatc ttcagtagat ccattaatgc aactcgtagg tggtcatcct tatttgttgc 16501 agcaggcatt ttctcacctc aaaagttatc ctgatatcac tcttgagcaa atgttagccg 16561 aggctagaac tgacgcaggt atttatcgcc atcatttaag acaattttgg ttgagtttac 16621 aacaggaacc aaagctgatg gcagcatttg aaacagtgat ttcttctact gagccagtga 16681 gattggaaac aatatcagct tatcagttgc agagtatggg tttggtgaag cttgcgggta 16741 atgaagttga gccacgttgt cagttgtatc gtagttattt tagtgatgtg attgggagtt 16801 cagaaggtgt ctgacgctga aattattcaa tctcctccaa aaaaaaaccg acttttttaa 16861 taagtcgagg ttctaattct ttttattttc acaaatcaga taggattgcc atatagcagt 16921 ccctaaaaaa ggcgaggagc gattgcaagt caaatctatt acaaaagata agcgatcgct 16981 attttaagtt tacgaaatcg catctaattc tgctatccag gcattaagag tttccatgtt 17041 tacacctaat tgacgtaatg ctaagtctag gcacaatttt ccgttgatac caggtttata 17101 gcaagcattt atcaagtcct tttttttctg ttttatatca gatattagta aaacaaaaca 17161 tgttttgcgg tctagaacag tattttcgca tacattgaat aagctttctt tcttattcgg 17221 tttcttccat gcttctgcga aattttgaaa aatagaagct aaaccttctt ctgtattgct 17281 tatctgtgga tcataatcag aagcatcagc aagtaaatta tttgattctc ctaaatccag 17341 tagtctcaac gtaatatttt cagtagggaa ctgcactgta gcggcaggaa ctatttcctg 17401 ggaaagacta ttagttgcag caaaggtgct tgttgtcgga actacccaca gaaaaattgc 17461 taggagtgcg atcgcgaaac gaccagcata ggcgatcgct atcttgcagt atgtactcat 17521 tttcaaggct tttcctgaaa aaatctgagg taattgcttg aatattttca tgactcttct 17581 cctttgttga tgggtaggag cgttcgctac gcgaacgctc ctaccgatgt acttcagcta 17641 catagaatat gctctcaagg gtaagcttcc agcgtgagta agttactaat cagactagaa 17701 atattaccct gaactccaga tttttgaaac acgccgttct ttttactcgt atggtcctga 17761 gcaagtacct gtggcactgc agcaataaca aacacaacct gcgcctagtt gcacttcgca 17821 tctaggcatc caaccagctg gacaatcatt ccgggttaca atacagccta gacccttcgc 17881 atgacacgca caaggattaa atacgctggc ttgaattcca ctactcatgg cgtacgttgc 17941 aatactcaaa ttcctctgaa caggtactac ttgaattgga agtttcat //