LOCUS NC_018876:14 22774 bp DNA linear BCT 23-OCT-2012 DEFINITION Methanolobus psychrophilus R15 chromosome, complete genome. ACCESSION NC_018876 SOURCE Methanolobus psychrophilus R15 chromosome, complete genome. COMMENT locus start: 2277160; locus end: 2299933 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.541808; n0_4mer:D = 28.574903; n0_4mer:PS = 38.226337 FEATURES Location/Qualifiers source 1..22774 /organism="Methanolobus psychrophilus R15 chromosome, complete genome." gene complement(1..1047) /gene="" /locus_tag="" /db_xref="2277160..2278206" CDS complement(1..1047) /gene="" /product="pseudaminic acid synthase" /translation="MEIRIADRCIGERHPVFIIAEVSANHLQNFDLAVDTIRAIKESG ADAVKLQTYTPDTITIDCDNEFFQIEHGTLWDGKTLYNLYKEAYTPWEWQPELKRIAE ELGLICFSSPFDTTAVDLLEKMEVPAYKIASFEITDIPLIEYVASKGKPVIISTGIAT LSDIEEAIASCKRMGNQQIALLKCTSAYPAPLEELNLKTIPNIIDTFRTVVGLSDHTL GIAVPIASVALGAKIIEKHFILDRNMGGPDAAFSLDFHEFESMVKAVRDTEKALGEVT YELTEKAKKSRDFSRSLFVVEDINTGEKFTEKNIKSIRPGFGLHTRFLTEILQKKARK DIKKGTPLRWDCIE" gene complement(1116..1520) /gene="" /locus_tag="" /db_xref="2278275..2278679" CDS complement(1116..1520) /gene="" /product="HAD-superfamily hydrolase, subfamily IA, variant 1" /translation="VDVYREHCPEISLREDIEVFLWKLSKEYKLCLLTNGWLMPQKMK VEALRLERYFDTIFYSQQDGLDFAKPHPKYFTQVLQFYDIEASEALMIGDDPIADIQG AKNLGMPHFQVRNELNDHEKQQIARILHDNMQ" gene complement(1726..2724) /gene="" /locus_tag="" /db_xref="2278885..2279883" CDS complement(1726..2724) /gene="" /product="CarB protein" /translation="MKRKKIIEMTETTILITSVSTKVLLVKEFKKALAEEKNEGKVIG IDIDSLSAALYFCDEYTICPRLNSPNYLDFIEKLCTENKVRLIVPTRDEDVLYLSKHK KHIEDRTMAKVMVPDPMVANMCSDKFEFFRFLQENDLPAITSWTQISDDITYPCVLKS KTGAGARKFYIVKDKGELHELIGNIDDPIIQEYIEGTEYSIDYFSDLDGNFISLVPRV RIKVVSGESKVGITVNDQEITDLCILLATKMKLIGHNVIQCFKTGLGEVKFIEVNPRF GGASNLSFAAGRNTPLYLIKLLNKGKIDVEPFKEGLMMLRYSEDIFIDAHDKNNYL" gene complement(2702..3637) /gene="" /locus_tag="" /db_xref="2279861..2280796" CDS complement(2702..3637) /gene="" /product="NAD-dependent epimerase/dehydratase" /translation="MFFNNKKVLVTGGAGVIGKELIDMLRKQGAIIRCVDFQEKPSEL SNIEYFQMDLSRPDNQFLFRFEPEYVFHLAADFERTEERKDFWESNFKNNILASHYLI DQIIKYPSLKKVIFASSYLIYDKEQYNNIEEQNHLTESSTISPRNTVGVAKLQTEADL EFLSRNNEYPFDTVSARIFRVYGKGSRDIISRWIRDILQEKDIILFNEDNRFDYIFAR DVAAGLLKLGESNNATGIYNLGTGVSSKVKDVITILKKNLGDFNVNAIESRKELYESS CADISKMQKELSWSPQYDLESGIREIISYEKKKNH" gene complement(3648..4169) /gene="" /locus_tag="" /db_xref="2280807..2281328" CDS complement(3648..4169) /gene="" /product="putative ribosomal-protein-serine acetyltransferase" /translation="LEADGLYLSNIEFGDLENIKKWRNEQMSILRQWKPLTDRNQEKY WDIIANSNDSVLFSIIDENDRFVGYCGLTNIDYISSRGELSFLLDTDLECDNTVHDKT LLAVLKMLSQYGFGQLNLNKIYTETYVYRESHIKTLESFGLKRDGILRKHVFKNGEYH DSVMHSMLRSEYL" gene complement(4226..4966) /gene="" /locus_tag="" /db_xref="2281385..2282125" CDS complement(4226..4966) /gene="" /product="acylneuraminate cytidylyltransferase" /translation="MKIVAIVQARMGSTRLPGKVMRTILDKPIILWDIDRISSSTLID EIVIAIPYGDENDIIDITIKQYSDKIIVLRGSESDVLDRYYKAAVQTKADIIIRITSD CPLIDPTIIDKVIEEFLNKDCDYCSNTLKLTYPRGMDTEIFTFNVLERAWNEAKEDYE REHVTPYIREHTDFFKQHNVSNEEDLSHLRLTLDTVEDFDLITKIYQHLYPTKKMFLL KDIKELLDKQPELIKINEHIMQTAVHSK" gene complement(4975..6114) /gene="" /locus_tag="" /db_xref="2282134..2283273" CDS complement(4975..6114) /gene="" /product="hypothetical protein" /translation="MIPYGHQTIDDEDIEEVIKVLKSDWLTTGPKIPEFEKAICEYVG CSYAVAMNSGTSALDVAVASLDLPKGSEVITTPFTFAATSNALLYNRLKPVYADIERE TRNIDTEDIERKITPRTKAIIYVDYAGHPCNIEEIQDIANEHDLYLIEDACHSFGAAY HGKKIGNFADITVFSFHPVKPITTGEGGAVVTNDSELAKKAKMLHSHGIDRDAISRYG PNAGWAYDMKMLGRNYRMTDIQAALGISQLKKIDRFIEKRNYIASYYQELLQDMDSIS IPPVKDGIRHGWHIYTVLLEESINRDDLFKYLRAEKNIGTNVHYIPVYRHTYYQETFG LKEKDYPVTEDVFKRIITLPLYPSMEEKDVEYVASSISDFIKNKG" gene complement(6111..6452) /gene="" /locus_tag="" /db_xref="2283270..2283611" CDS complement(6111..6452) /gene="" /product="hypothetical protein" /translation="MVSMNYEDEPFNCVHSYVVSIEPMKTRANHYHRNKEEWLALAAG KVKLCLKDIVSGKYEEIVLDSKSDAYEVIHIRPYVAHALRNISNGEASVIVFSKNAED KEDTIPYEVAL" gene complement(6521..7504) /gene="" /locus_tag="" /db_xref="2283680..2284663" CDS complement(6521..7504) /gene="" /product="UDP-N-acetylglucosamine 4,6-dehydratase" /translation="MQLKTDESLFDGKNILLTGGTGSFGKKFTEVMLREFNPSSLRIY SRGEFNQYQMKQEFNDKRLRFLIGDVRDRDRLYRAMNGIDIVVHAAALKQVPACEYNP IEAVKTNIDGSVNVIDAAIDNSVEKVMAISTDKAVHPVNLYGATKMVAEKMFVQGNTY TGKGRTRFSCVRYGNVIGSRGSVIPLFNEQKEEGVLTITDERMTRFWLTLDQGVHFVL SSIQRMHGGEIFIPKIPSMKITDLADAIAPEATKMFTGIRPGEKLHEIMITEDESRHA KEFSDYFVIEPEFSFWKKENTSSGKSLPDNYRYSSDINDKWLTTEQLKQIL" gene complement(7733..9019) /gene="" /locus_tag="" /db_xref="2284892..2286178" CDS complement(7733..9019) /gene="" /product="hypothetical protein" /translation="MIIICEPIARGLTHEKVNSGFIYGLRLAYPEEAIRFYADISHIE AIQNILDYDKITIDNIEYIPAKFRNLYTIRGVLKYYSPFNEIFSDAIEFKVNKIFFFS FNPAILYAIKKLKKRRKFHEMKFTFVLHGSFDTVANEYSKPTQLSLPIKRIKNQTDIT YKLQIIRQVKLTELPKVIAQFINRFMPWQLISNKLFTNRKMLLWNHSADYRYIALSPH IIKNAERYIDVKKLNMYTVILPTVFKEPSAQLDNEYAKFAIFGYGNPLMLHNILVQLS QKDMKHPYEIRIIGMDNRGTSDFPNVTCPCPGKRLDRSEMEKYAADIDVFLILYDKSR YRLSCTGSILESLSYMKPILHFDNDCINAFNRPENPIGIRCNSLEEFVCKMEDIIENY KSYSLEFQNFKKNILKLRNECAIENSVNTLKESFTW" gene complement(9016..9891) /gene="" /locus_tag="" /db_xref="2286175..2287050" CDS complement(9016..9891) /gene="" /product="NAD-dependent epimerase/dehydratase" /translation="MKAIIFGINGQDGYYLTQLLTLNRVDVIGVSRSHGYIKGDVADY SFVESIIKHHQPDYVFHFAANSTTAHSALFDNHNAISTGTLNILECVRLHCPKTKVFL SGSAMQFKNEGVPIDEQTPFEANSAYSVARIQSVYAGRYYRSAFGLQVYVGYFFNHDS PLRSERHVNQKIVSAVKRIANGSSEKLKLGNIDVKKEFNYAGDVVEAVWILINQDTVF EAMIGSGIAHSIREWVEYCFKKVNKNWEEHVIINHEFVPEYEMLVSNSELIRSIGWKQ KVDFYKLADMMMETQ" gene complement(9900..11723) /gene="" /locus_tag="" /db_xref="2287059..2288882" CDS complement(9900..11723) /gene="" /product="hypothetical protein" /translation="LNNNRVLFVTHKKCQCGVYEFGENVFDALKLSKKYNFIKVECSN INELKEHFEKERPIAIIYNYMPATMPWVTSAIFRYGILKNNIADIPVPQIGIIHSIMQ NIADSVKQGKKYAIYHPEFANRLFDFYIAPDPTLLLKNPYVFKHGRPVKEYVNKYPTS DKLKIGSFGFAKTGYEDMIELVQSEFDEAEIRLHIPFAKFGDIDGKKAKSIGNDCRKL LRKPGITLSISHDYLDEEAVLDFLAQNTINVFLRDDKGRGISSVIDYALAVNRPIAIS NSRMFRHILDSKPSICVAEKPLREIINNGTTPLIKYTKEWTPENLCWEYERIIDSILI RGKTTNIQKIKHILKDTLGLVIKSHDNPNKNNWLSTTKYLYEDDYTKTLNNVSYEPLA VESISNFNGILDNRARELYKPAVKHLFELVPKTMEKKIPEANVQQAFVFDTVYRHLKE YKNPKILSVGSYQDTACMALIKMGIVVEEIDPMFNYTLQEFATKPDTIKGSYDIIFST SVIEHDPDDKSFVECITELLAPNGIFVMTCDYKDGWKQGDPKPRVCARLYTKVDLEHR LLSYMKNCKLIDEPNWECPNPDFVFGNYKYSFASFVVKKEM" gene complement(11739..12968) /gene="" /locus_tag="" /db_xref="2288898..2290127" CDS complement(11739..12968) /gene="" /product="C-methyltransferase" /translation="MYTEINKCRISGSTNLVTVLSLGEQCLTGVFPKSPNEPITKGPL DLVWCPDSGLLQLKQLYNLNEMYGESYGYRSGLNSSMVRHLQQKIRILEQMVKPNDDD MVIDIGSNDATSLKAYTGKFKKVGIDPTGKKFKQYYTDEVTLIPDFFSATIFKTNFPN RKAKIITSIAMFYDLEDPMAFVKDIEAVLADDGIWHFEQSYMPSMLRTNSYDTICHEH LEFYSFKVVKNMLERCGLRVVDVQMNQINGGSFAVTACKENGPYKSNLPIINWVLKQE NAMGLDTPKPYLDFAERVFQHRESLTELIESLIADGKKVIGYGASTKGNVLLQFCGFT TKHIPCIAEVNEDKFGSYTPGTDIPIVSEKEARAMNPDYFLVLPWHFKHNILDREHEF LAHGGKFIFPLPYIEIV" gene complement(13066..14544) /gene="" /locus_tag="" /db_xref="2290225..2291703" CDS complement(13066..14544) /gene="" /product="polysaccharide biosynthesis protein" /translation="MFKLETFVSRIMSIDAIRRQSIASLIWQIALTFIGFLSTIYFAH AAGASVLGGYFLFLAYLSIINLVADGGFGGAAIKRISEGEEQDAYFSAFIVLRSVFVI LVVVVLITFRSYFVNLNDSGIFIWLILSLIVGILGGVIQSGINGCGKMGISATAGFIN SFSRIIVQIVAIFMGYGVAGLAGGFVVGIVVSSIVQLRFFDLHFVRFRWRHIKSLSTF SLWVFLISGGGIVFSTADTVMIGYYLDNADVGVYRIILQFTLLVSFTTVALGSTLYPR VSRWRKTNDMRLIEKSLPRAFTYSLVVAIPMLVGGFLLGDKLLYYFYGAEFGREYMTM AVLFIVQTVSIFNFFFTTYLTAMDYLKDLFKITVVSVVVNIVLNASFIPLIGILGAAI ATLITTGLNTVLALWVLSKILTIRVESNSLWNILKASIVMGLFLGGYRWLMPLSNVWL TLIPVVVGTVIYGILLLKFDRKIYEELKGILVKMNVSQPKQF" gene complement(14591..15625) /gene="" /locus_tag="" /db_xref="2291750..2292784" CDS complement(14591..15625) /gene="" /product="GDP-mannose 4,6-dehydratase" /translation="MTKTALITGITGQDGAYLAEFLLNKGYIVHGIRRRSSSFNTKRI DHLYRDTHEKNVNLFLHYGDLTDSASLIRIIQETQPDEIYNLAAQSHVHISFDTPEYT ANSDAVGTLRLLEAIRILGLEKKTRFYQASTSELYGKVQEIPQKETTPFYPRSPYAVA KLYAYWVTINYREAYGMYACNGILFNHESPIRGETFVTRKITMAVAKIKNGLQNKLYL GNLDAKRDWGFAGDYVEAMWLMLQQDEPDDFVIATGETHSVREFVELAFKEAGIKIEW EGKGVDEVGMDAATGDVLIEVDPRYYRPTEVDILIGNPTKAKKKLGWESKIGLQELVK MMVEEDMKDL" gene complement(15651..16577) /gene="" /locus_tag="" /db_xref="2292810..2293736" CDS complement(15651..16577) /gene="" /product="NAD-dependent epimerase/dehydratase" /translation="MRSIVTGGAGFLGSHLCDLLIEKGHKVICIDNLVTGKTKNIEHI RFENFTYLKHDITKPVYFGDKIDYIFHLASPASPVDYLELPIQTLKVGALGTYNMLGL AKEHKARLLLASTSEVYGDPLVNPQPETYWGNVNPIGPRGVYDEAKRYAEAITMAYHT HHGIETRIARIFNTYGPRMRANDGRVVPNFINQALKGEDITVYGDGKQTRSFCYVSDL IEGIYRLMMSEHTDPVNIGNPAEMTVLEFAERIIEITGSVSRIVYEELPVDDPKVRRP DITRAREVLGWEPKVKLADGLRETIEYFKQVE" gene complement(16589..17599) /gene="" /locus_tag="" /db_xref="2293748..2294758" CDS complement(16589..17599) /gene="" /product="putative glucose-1-phosphate thymidylyltransferase" /translation="MKVIIPAAGAGTRLFPHTHTKPKPMVFIAGKPIIGHILDRMIDL HPEEIILVVGYRKEQLISYVDKHYSSIFNIRYVCQENRMGLGHSVYLAKEHIRDSETM IALGDMIFKSGYKDFHDQYCQNGACSASIGVREVEEPRKYGIVYLKEQSSHIERLEEK PENPSSNLGIAGVYFIKDTPLLLNILEWMIENGVKTRGEYQLTDALQEMVSRGSELKT FEVSSWYDCGHATSLLEANRILLSEQESKQEVYDSISSVIIPPVIFGTNVKIVNSVIG PFTSIAEDSVIENSIISNTVIGSRTHLSSVNLQSSIVGDDANVIGKHNSLNIGDSSSI EF" gene complement(17704..19077) /gene="" /locus_tag="" /db_xref="2294863..2296236" CDS complement(17704..19077) /gene="" /product="mannose-1-phosphate guanylyltransferase (GDP)" /translation="MCIKSIILAGGSGTRLWPLSRELYPKQFLKIKDRSLFQDTVLRC LQVSDISEIYVVTNEVHKYFAIGQVEELGYDLPVENLLLEPEGKNTLPAICYGMKEID KAHGRSVVGVFSSDHVLDPIAMETISGAEKLTSGYMVTFGIAPSSPHTGYGYIKPGEE LEIGHKVSEFREKPCQEDAQRYISEGCLWNSGMFLMDTGVFLEEVQQLAPDVWNAFEN SGTIQEIYAEMPNISIDYGIMEKSSRVSVVRLGCKWSDLGNFDAFYSEWEKDKSNNCT LSCQNVFVDSGNNFVHSNSNKLVSLIDINDMIVVDTTDALLICPRKSSEKVKEVVGFL RKRNDERINIHETVYRPWGSYTLLENSGGHKIKNIAVLPGKKLSLQLHHHRSEHWVVV KGMACVENDGQKFFLRQGESTFIKAGSKHRLSNSGRLPLEIIEVQLGEYVEEDDIVRF DDEYGRA" gene complement(19209..20321) /gene="" /locus_tag="" /db_xref="2296368..2297480" CDS complement(19209..20321) /gene="" /product="transposase, IS605 OrfB family" /translation="MLKAYKYRIYPTKEQEELFYQHFGACRFVYNWALEHKIKSYQQD SKSVSRFTLNKMITGLKVEHEWLKDVNSQSLQGATLNLENAFTKFFREKKGFPTFKSK KNQVQSFSVPQFYEVDFDNNKIKLPKIGWIKTKLHRKFKGIEKTATVSGTSTGRYYIS ILVDDKQETPVKSLFNEKVTVGIDVGIKDFAVLSNGEKIDNPKYLKTSLERLNALQRR MSRKQNGSKNRAKARLEVSKLHEKISNQRNDFQHKLSSKLIGENQALALETLNVSGML KNHCLALHIADASWSSFVSKLEYKAEWFGKTILRIGQFEPSTKICNMCGYHNGKLTLA NRKWQCPDCKTNHDRDINAAINIKKFALDKQNLIRI" gene 20559..21401 /gene="pyrK" /locus_tag="pyrK" /db_xref="2297718..2298560" CDS 20559..21401 /gene="pyrK" /product="ferredoxin-NADP(+) reductase subunit alpha" /translation="MSYTILEKKQIAPQVHLMKVLAPDVAKAAKAGQFIILRIDETSE RIPLTIADFDTGEGYVTIIFQEMGKTTKQLAKMSNTDVLQDFVGPLGKPADVQKLGTV ILVGGGVGIAPVYPQVKAYREAGNKVISIIGARNKDLLILEDEMQDASDELYVATDDG SKGHHGFVTEVAKKILDSGEKIARIVVIGPPILMKVAAGMTAPYGVETIVSLNPIMID GTGMCGGCRVSVDGETKFACVDGPEFDAHKVDFNLLMSRLGLYRSEEAQCQEDHNCTC RSGN" gene 21401..22774 /gene="" /locus_tag="" /db_xref="2298560..2299933" CDS 21401..22774 /gene="" /product="putative oxidoreductase" /translation="MAARQPMPHQDAKERARNFDEVALGYTKEQAIAEASRCLECRNP KCVQGCPVNIDIPGFIAQIKTGNFDEAIATIKLTNSLAAVCGRVCPQEVQCEELCVLA KKGEPVAIGRLERFCADHEREKGVVPPVRTQPSGRRVAVIGAGPAGLTAAADLAKAGH AVTIFEALHDTGGVLTYGIPEFRLPKSIVQEEVDYIRQLGVDFKVDYVIGKIKILDEL RNDFDAIFLGTGAGLPKFMGIEGENLNGVYSANEFLTRVNLMKAYLFPYHGTPVKRGK KVIVVGGGNVAMDAARSALRLGAEEVSIVYRRGEHELPARKEEVENAKEEGVVFRLLT NPVRILQGENMTVKGVECIRMELGEPDESGRRSPVVKEGSEHVIDADIVIIAIGTSPN PMILSGSDGLKVGARGNIIVDESARTSLENVCAGGDAVTGAATVISAMGAGKLAAQTI NEYLMNN" ORIGIN 1 ttattctata caatcccatc ttaaaggagt acctttctta atatctttcc ttgctttttt 61 ctgtagtatt tcagttaaaa atctagtatg taacccgaaa ccaggtctta tagatttaat 121 atttttttca gtgaattttt ctccagtgtt aatatcttcc acaacaaata aggatcttga 181 aaaatccctg cttttcttgg ctttttctgt tagctcataa gtcacttcac cgagtgcttt 241 ttctgtatct ctgacagcct tcaccattga ttcgaattca tggaaatcaa gtgagaatgc 301 agcatcgggc cctcccatat tcctgtcaag gatgaaatgc ttctcaatta tttttgcacc 361 aagcgcaaca gatgcgatag gtacggctat cccaagggtg tgatcagaaa gcccgacgac 421 tgttctgaaa gtgtcgatta tgttcggtat tgttttcaga ttgagttctt cgagtggcgc 481 aggatatgca gatgtgcatt tcaatagtgc tatctgctga ttccccatcc ttttacagga 541 agcaatggct tcctctatgt ccgagagtgt tgcgatacct gtggatatga taaccggttt 601 tccttttgat gcgacatatt ctatgagtgg gatgtctgtt atttcaaagg atgcgatttt 661 gtaggcaggg acttccatct tttcaagaag gtcaactgca gttgtgtcaa aaggagagga 721 gaaacagata agtccaagct cttcagctat ccttttaagc tccggttgcc attcccaggg 781 ggtatatgct tccttataga gattataaag tgtcttccca tcccacaggg ttccatgttc 841 tatctgaaag aactcattgt cacagtcgat cgtaattgta tcaggtgtat atgtctgaag 901 ctttacagca tcagcgcccg attctttaat ggctcttatt gtatcgactg caaggtcgaa 961 attctggagg tggttcgctg aaacttccgc tattatgaat accggatgtc tttcaccaat 1021 gcatctgtca gcaattctga tttccatgtt tccctcaatt gtatatttgt tagcattgat 1081 agtcatttac tttagtaatt tagttcccgt cttcctcatt gcatgttgtc gtgcaggatt 1141 cgtgctatct gctgcttttc atggtcgttc agctcattcc tgacctggaa atgaggcatg 1201 cccagattct tcgctccctg tatatctgca atggggtcat ctcctatcat caaggcttca 1261 gaggcctcta tgtcgtaaaa ttgcaggacc tgcgtgaagt atttagggtg gggttttgca 1321 aagtccaatc catcctgttg tgaataaaat atagtatcaa aatatctttc aagccttaac 1381 gcctcaactt tcattttctg aggcatcaac catccgttgg taagcagaca aagcttgtat 1441 tcctttgata gtttccaaag gaagacttct atgtcttccc tcagggatat ttccgggcag 1501 tgctctcgat agacatccac taacttgctg ataatacagc tatcaatgtt cagtttccta 1561 cacagataat cgaaattgtt ccctcttcca ttgagaacga atgattctaa tagtgaagag 1621 taaactgcgt aatgattcag ggacttttcc ttcgctaaga aaatagcaac ggctttaaac 1681 ccactgatga cgtattctct ttcattgtac aacgtgttat ccagatcaaa gataattatt 1741 tttgtcatgt gcatcaataa atatgtcctc actataccgt agcatcatga gaccttcttt 1801 gaagggctcc acgtcaatct tgcccttatt cagtagtttg atcagataaa gaggagtgtt 1861 tctgccagct gcaaaactta aattagatgc tcctccgaaa cggggattca cttcgatgaa 1921 ttttacctcc cctaatccag ttttaaagca ttggatgaca ttatggccta ttaatttcat 1981 ttttgtagca agtaaaatgc acaggtctgt tatttcctga tcattcactg tgattccgac 2041 cttcgattct cctgagacga cctttattct aaccctaggg accaggctga taaaattccc 2101 atcaagatct gaaaaataat ctatactgta ctcggtccct tctatatatt cctgtattat 2161 ggggtcatca atatttccaa tgagttcgtg caattctccc ttgtctttaa caatatagaa 2221 ttttctggca ccggcacctg tctttgattt gagtacacaa ggataagtaa tgtcatcaga 2281 gatctgtgtc catgacgtta ttgctggtaa atcattttcc tgtaagaatc tgaagaattc 2341 aaacttatct gagcacatat ttgcgaccat gggatcagga accatgacct ttgccatagt 2401 tctgtcttca atatgttttt tgtgttttga caggtaaagt acatcctcat cccttgttgg 2461 aacaataagg cgcactttgt tctcagtaca cagtttctct atgaaatcca gatagttagg 2521 actattcagt cttgggcata tcgtatactc atcgcagaag taaagtgctg cagaaaggga 2581 gtcaatatct atccctatta ctttcccttc attcttttct tctgccagcg cttttttgaa 2641 ttcttttaca agcagcactt tcgtagaaac actggtgata aggattgtgg tttcagtcat 2701 ctcaatgatt ttttttcttt tcataactga ttatctctct gattcctgat tcgagatcgt 2761 attgaggaga ccaagacaat tctttttgca ttttacttat atctgcacaa cttgattcat 2821 atagctcttt tctggattcg attgcattga cattgaaatc ccctaggttc ttttttaaga 2881 ttgtaataac atctttgact ttagaagata caccggttcc taaattgtag atgcctgtag 2941 cattattgct ctcacctagt tttaatagtc ctgcagctac atcccttgca aatatatagt 3001 caaatcgatt atcttcgttg aacaaaataa tatccttttc ttgaaggata tctcttatcc 3061 accgggaaat tatgtcacgt gatccttttc catatactct gaatattctt gcagacacag 3121 tatcaaaagg atattcatta ttccggctaa ggaattccag atcagcttct gtctggagct 3181 ttgcaacacc aaccgtgttc ctgggactga tggtagaact ttcagtcaaa tggttttgtt 3241 cttcaatgtt gttatactgt tctttgtcgt atatcagata actggatgca aagataacct 3301 ttttcaaaga agggtatttg ataatctgat cgatcagata atgagatgca aggatattat 3361 tcttgaaatt ggattcccag aagtcctttc tttcttcggt tctttcaaaa tcggcggcta 3421 aatgaaaaac gtattcaggt tcaaagcgga aaaggaactg gttatcaggt cttgaaagat 3481 ccatctggaa gtattctata ttactcagtt ctgaaggctt ttcctgaaaa tccacacatc 3541 ttattatggc tccctgcttc ctgagcatat caatgagctc ttttccaatt actcctgctc 3601 cgccggttac tagtactttc ttgttgttga aaaacatgat gatcacctta taaatattcc 3661 gaccttaaca tcgaatgcat cacactgtca tggtattcgc catttttgaa aacgtgtttt 3721 ctgaggatac catctctttt cagtccgaag ctttccagtg ttttgatgtg actttccctg 3781 taaacatagg tctctgtata tatcttattc aaattgagct gcccgaatcc atattgtgag 3841 agcattttga ggactgcaag cagcgtttta tcatgtacgg tattgtcgca ttcaagatca 3901 gtgtccagta aaaaagataa ttctcctctt gatgatatgt aatcaatatt ggtaagacca 3961 caataaccaa cgaacctgtc attctcatcg attattgaaa aaaggactga atcattacta 4021 ttggcaatga tatcccagta tttctcctgg tttctgtcag taaggggttt ccattgacga 4081 agtatggaca tttgctcatt gcgccatttt tttatatttt ccagatcacc aaactctatg 4141 ttcgataagt atagaccatc tgcttccaat attctagctc tcatgagcaa atctcctata 4201 atatgttaac gaaaagcatt acattttact ttgaatgtac cgctgtttgc atgatatgtt 4261 cgtttatctt tattaactct ggttgtttat ccaataattc cttgatgtct tttagcaaaa 4321 acattttttt tgtagggtat agatgttgat agatttttgt gattaagtca aagtcttcta 4381 ctgtgtccag tgtaagtcgt aagtgactca agtcttcttc atttgataca ttatgctgct 4441 taaaaaaatc agtgtgttct cttatatatg gtgttacatg ttctctttca taatcttctt 4501 ttgcttcgtt ccatgctctt tcaagcacat tgaacgtgaa aatttctgta tccattcctc 4561 ttggatatgt aagctttaaa gtattggaac agtaatcaca atctttattc agaaactctt 4621 caataacctt atctattatg gtagggtcga ttaatgggca atctgatgtg attctaatta 4681 ttatatcagc tttagtctgt acagcagctt tataatacct gtcaaggacg tcgctctcac 4741 ttcctctcaa cacgatgatt ttgtcactat attgttttat cgtgatgtca ataatgtcgt 4801 tttcgtcacc atatggtata gcgatgacaa tttcatcaat taatgtggaa ctagatattc 4861 tgtcgatgtc ccaaagtatt ataggcttgt ccagaatagt tctcataact tttccgggaa 4921 ggcgggtgga tcccatcctt gcttgaacaa tcgccacaat tttcatattg aattctatcc 4981 cttatttttg atgaaatccg atattgagga tgcaacgtat tccacatctt tctcttccat 5041 gctaggatac aatggcaacg taattattct tttaaaaaca tcttcagtca caggatagtc 5101 tttttcttta aggccaaagg tctcttggta gtaagtatgt ctgtaaacag gtatgtaatg 5161 aacatttgtc ccaatgttct tttctgctcg caggtatttg aaaaggtcat cccggttaat 5221 agattcttca agtaggaccg tatagatatg ccatccatgc ctgataccat ctttgaccgg 5281 aggaatgctt attgagtcca tatcctggag cagttcctga taatatgagg cgatatagtt 5341 ccttttttct ataaaacggt ctattttttt tagctgggat attcccagag ctgcctgaat 5401 atcggtcata cgataattac gtccgagcat tttcatatca tatgcccatc cggcattggg 5461 accgtagcgg gatatagcat ccctgtctat tccatgacta tgtaacatct ttgctttttt 5521 ggccagctct gaatcatttg tcactactgc ccccccttct cctgtagtta taggttttac 5581 cggatgaaaa ctgaatactg tgatatctgc gaagttgcct atttttttac catgataagc 5641 ggctccaaaa gagtggcaag cgtcttcgat caaatagaga tcatgttcat ttgctatgtc 5701 ctgtatttct tcaatattgc atgggtgccc tgcataatcc acatagatta tcgcctttgt 5761 tcttggcgtg attttccgct caatgtcctc cgtgtctatg ttacgtgttt ctctttctat 5821 atctgcataa actggtttca gtctattgta aagaagtgca ttactggtgg cagcgaatgt 5881 gaagggggtt gtgatgacct ctgaaccttt tggcaggtcg agtgaagcta ctgcgacatc 5941 cagagcactg gttccgctat tcatagctac agcatagctg catcccacat actcacagat 6001 ggctttctcg aattcgggta tttttgggcc ggtggtcaac cagtcacttt tcaggacctt 6061 tatcacctct tcgatatctt catcatcgat tgtctgatgt ccataaggga tcataatgca 6121 acctcgtagg ggattgtatc ctctttgtcc tctgcattct tactgaaaac tataacgctt 6181 gcttcaccat tcgaaatgtt ccttaatgca tgggcaacat atggccggat atgaatcact 6241 tcataggcat ctgattttga atccagaacg atctcttcat atttcccgga aactatatcc 6301 tttaaacaca acttgacctt tccggcagcc agagctaacc attcctcttt gttcctatga 6361 taatgattag ctctggtttt catgggttcg atagatacta cataagaatg cacgcaattg 6421 aatggctcat cttcatagtt catcgatacc atctctgaga gccatccgtc ctccctttta 6481 tgtttgaccc gtataagttt attgtataac atggacccaa ttacaatatt tgtttcagct 6541 gttctgttgt aagccatttg tcattgatgt cgctggaata ccggtagtta tcaggtaggc 6601 tctttcctga agaagtgttt tcctttttcc agaatgagaa ctctggctcg atcacaaaat 6661 agtcagagaa ttcttttgca tgccttgatt catcttctgt tatcatgatc tcgtgcagtt 6721 tctctccagg tcgaattcct gtgaacattt ttgttgcttc aggagcgatt gcatctgcta 6781 gatcagttat tttcatactg ggtattttcg ggatgaaaat ttcccctcca tgcattctct 6841 gtattgaact aagcacaaaa tggacacctt gatcaagagt tagccagaaa cgtgtcatcc 6901 tttcatcggt gatcgttaaa actccttctt ctttctgttc attgaacagt ggtatcacgc 6961 tccctcggct acctatcaca tttccgtatc tgacacaact gaaccgggtt ctcccttttc 7021 ctgtataggt attgccctga acgaacattt tttctgcaac catttttgtt gccccataaa 7081 ggtttacagg atgaacggct ttgtctgtgc ttattgccat cactttttca acagaattat 7141 caatagctgc atcaattaca ttgacagagc cgtctatgtt tgtcttcacg gcctctatgg 7201 ggttgtactc acaggctggg acttgtttta acgctgctgc atggacaacg atatcaattc 7261 cattcattgc gcgatagagc ctgtcacggt ccctaacatc accaatcagg aatctgaggc 7321 gcttatcatt aaattcctgt ttcatttgat actgattgaa ttcccctctg gaatatattc 7381 tcaggctact cggattgaat tccctaagca taacttcagt gaacttttta ccaaaagagc 7441 cggttccgcc tgtgaggagg atattcttgc catcaaataa agattcatca gttttcaatt 7501 gcatgtttcg accatctcta atttagaata tataagttat tatggacatt ttattatata 7561 aagtcatttt cgactctgca tatctctctc tttctgcttc atctttatgt attctccaaa 7621 agaaaataca ctctgtcagt tattaatatg tttcctgttg aaagggtgtg aagcgaagat 7681 tactggaact tggtcgggtt tattgaacag cacattctaa gaaaagctac aattaccatg 7741 taaaactttc ctttaatgtg tttactgaat tttcaatggc acattcattg cgtaatttca 7801 agatattctt tttgaaattc tggaattcaa ggctatatga cttgtaattt tcaattatat 7861 cttccatttt gcacacaaat tcctcaaggc tattacaacg gattccaatt ggattctcag 7921 gcctattgaa agcattgata caatcgttgt cgaaatgcag aattggtttc atgtaagaca 7981 gggattcgag gattgatcca gtacaactga gcctgtaacg acttttgtca tataatatca 8041 ggaatacatc aatatctgca gcatattttt ccatttcact tctatcaagt ctttttccgg 8101 ggcatggaca cgtgacgttc gggaaatctg aagttcctct gttgtccatt cctatgatac 8161 ggatctcata cgggtgtttc atatcttttt gtgaaagctg gaccaatatg ttatgcaaca 8221 tcaatggatt cccataaccg aagattgcaa atttggcata ctcattatct agctgggcgg 8281 aaggttcttt aaagacagta ggaagtatca ctgtatacat gttcaacttc ttcacgtcta 8341 tgtacctctc tgcattttta ataatatgag gcgacaatgc gatgtatcga tagtccgccg 8401 aatggttcca gagtagcatt tttcgatttg taaataattt attggatatc aattgccagg 8461 gcataaaacg attaataaat tgtgcgataa ccttaggtaa ctctgttaat ttcacctgtc 8521 tgattatttg aagtttatat gtgatatcag tttgattttt tattctttta attggcaatg 8581 atagttgagt tggtttagaa tactcatttg caacagtgtc aaaacttcca tgaagcacga 8641 aagtgaattt catttcatgg aattttcttc ttttctttaa tttttttatt gcataaagaa 8701 ttgcaggatt aaaggaaaag aagaaaattt tgttcacctt aaattcaatg gcatcagaaa 8761 aaatttcgtt aaaaggtgag taatatttga gcactcccct tatagtataa agatttctga 8821 atttagctgg aatatattct atattatcga tggtaatttt atcatagtct aatatgttct 8881 gaatggcctc aatatgtgat atatctgcat aaaacctgat tgcttcctct ggataagcta 8941 agcgcagtcc ataaataaaa ccactgttaa ccttttcatg agttaatcct cgtgcaatcg 9001 gctcgcaaat tataatcatt gtgtctccat catcatatct gctaatttat aaaaatctac 9061 tttttgtttc catccaatac ttcgtatcaa ctcagaattg ctaactaaca tttcgtattc 9121 aggaacaaat tcatgattta ttattacatg ttcttcccaa tttttgttga cctttttgaa 9181 gcagtattct acccattcac ggatgctatg ggcaattcca ctgccaatca ttgcctcgaa 9241 tacagtgtct tggtttatca gtatccagac agcttcaacc acatcaccgg cataattaaa 9301 ttcttttttt acgtctatat tgcccagttt aagtttttca gaacttccat tagcaattcg 9361 ctttactgcg cttacgattt tttggtttac gtgcctttcg gaccttaacg gactgtcatg 9421 gttaaaaaag tatccaacat acacctgcaa accaaatgca gaacgataat atctgcccgc 9481 ataaacagat tgaattcgag ctacagagta ggcactgttt gcctcaaaag gtgtttgttc 9541 atcgatgggt actccttcgt ttttaaactg catagcactg ccagataaaa acactttagt 9601 ttttggacaa tgtaaccgga cacattccaa gatattcaga gtaccagtgc ttatagcgtt 9661 gtggttatca aacaatgcag aatgggccgt ggtggaatta gctgcaaaat gaaaaacgta 9721 gtctggttga tgatgtttta ttatcgattc gacaaatgaa taatctgcta catctccttt 9781 tatatagccg tgggaccgag aaacaccaat tacgtcaact ctattcaatg ttaaaagctg 9841 ggtgaggtag taaccatctt gcccgtttat accgaagata attgctttca tagaacaaac 9901 tacatttctt ttttgacaac aaatgatgca aatgagtatt tgtaatttcc aaacacaaaa 9961 tcgggattgg ggcattccca attcggttca tcaatcaact tgcagttttt catgtaagat 10021 agcaacctat gctctaagtc aactttagtg tatagtcgtg cacaaacacg aggcttagga 10081 tccccttgct tccaaccatc cttataatcg caagtcatta caaatattcc attaggcgct 10141 aataattctg taatgcattc aacaaatgac ttgtcatcgg gatcgtgttc tattacggaa 10201 gttgaaaaaa taatatcata actgcccttt attgtatctg gttttgtggc aaactcttgc 10261 aaagtatagt tgaacatagg atctatttcc tctacaacaa ttcccatttt aattaatgcc 10321 atacaagcgg tgtcttggta gctacctaca ctaaggattt taggattttt gtattcctta 10381 agatgacgat agactgtgtc aaaaacaaag gcttgttgta cgttagcttc aggaattttt 10441 ttctccatcg tttttggcac taactcaaat aaatgcttca cagcaggctt atataactct 10501 cgtgctctat tatctagaat cccgttgaaa ttacttatgc tttcaactgc tagtggctca 10561 tagcttacat tgttgagtgt tttggtgtaa tcatcttcgt ataagtattt ggtagtacta 10621 agccaattat ttttatttgg attatcatgt gattttatga ccaatcctaa tgtatccttc 10681 aagatgtgct ttattttttg aatgttggta gttttccctc taataagtat ggaatcaatt 10741 attcgctcat attcccaaca taaattttca ggagtccact cttttgtgta ctttattaaa 10801 ggagttgttc cattattaat gatttctctc aatggttttt ctgctacaca aattgaaggt 10861 ttggaatcta aaatatgtct aaacatccgg ctattggaaa tagcaattgg tctgtttact 10921 gccaatgcat agtcgataac acttgatatt cctcttccct tgtcatcacg taaaaataca 10981 tttatagtat tttgagcaag aaaatcaagt acggcttctt catccaaata atcatgtgaa 11041 attgaaagtg ttattccagg ctttcgtagc aattttctac aatcatttcc tatactcttt 11101 gccttctttc cgtcaatgtc accaaatttg gcgaatggaa tatgtaatct tatctcagct 11161 tcatcaaact cgctctgtac caactcaatc atgtcctcat aacccgtttt tgcaaaaccg 11221 aaactgccaa tctttaattt gtcagatgtc ggatatttat taacgtactc tttaacaggc 11281 cgtccatgtt taaacacata ggggttcttt agcaaaagag ttggatcagg agcaatatag 11341 aaatcaaaca gcctatttgc aaattccgga tggtagattg catacttctt gccttgcttg 11401 acagaatctg cgatattttg cattattgaa tgaataatcc ctatttgtgg tactggaatg 11461 tctgcaatat tgtttttgag aattccatat ctaaatattg cactggttac ccaaggcatt 11521 gtagcaggca tataattata gatgattgca atagggcgtt ctttctcaaa atgttctttt 11581 aactcattaa tgttactgca ctctactttg ataaagttat acttttttga taacttgaga 11641 gcatcaaaaa cattttctcc aaactcataa acgccacact ggcatttctt atgcgtgaca 11701 aacaataccc tattgttatt caaaataaac cctccatttt aaacaatttc aatatatggc 11761 agtgggaaaa taaacttccc tccgtgtgct aaaaattcat gctctctgtc taaaatattg 11821 tgtttaaaat gccaaggcag caccaaaaaa taatcggggt tcattgccct cgcctctttt 11881 tcagaaacaa tcggaatgtc agtacctggt gtgtatgagc caaacttgtc ctcatttact 11941 tccgcaatac aaggtatatg cttggttgtg aatccacaaa attgaagcaa aacattccct 12001 tttgtgcttg caccataacc aataaccttt ttaccatcag ctatcaagga ctcaatcaat 12061 tctgtaagac tttctcgatg ttgaaaaact ctctctgcaa aatcaaggta aggcttagga 12121 gtgtctaaac ccatagcatt ctcttgttta agcacccaat tgataatcgg caaattagat 12181 ttatatggtc cattttcctt gcatgctgtc actgcaaaac ttccaccatt gatttggttc 12241 atctgcacat ccacaaccct tagtccacag cgctccagca tatttttaac tactttaaat 12301 gagtaaaatt ctaaatgctc atgacaaatg gtatcgtaag aattagtgcg gagcatacta 12361 ggcatatagc tctgttcaaa atgccatatt ccatcatcag caaggactgc ttcaatatcc 12421 tttacaaatg ccattggatc ttccaaatcg taaaacatgg caatagatgt aataatcttt 12481 gctttgcgat ttggaaaatt ggtcttaaat attgtcgctg aaaaaaagtc cggaatgagg 12541 gtaacctcat cggtatagta ttgtttaaac tttttcccgg taggatcaat tcctactttt 12601 ttgaatttac ctgtatatgc cttaagtgaa gttgcatcat tactgccgat gtcaataacc 12661 atatcgtcat cattcggttt caccatctgc tctaagatgc ggattttttg ctgtaggtgt 12721 cttaccatag agctgtttag acctgagcgg tagccatagc tttctccata catttcattc 12781 aaattgtata actgttttag ttgcaacaaa ccgctatcag gacaccacac aaggtcaagt 12841 ggacccttcg taataggctc gtttggtgat ttaggaaata cgcctgtgag gcattgttcg 12901 ccaagcgata atactgtgac aaggttcgtg ctaccactga tgcgacattt attgatttca 12961 gtatacatat tatttaatcc attagttgca ataagttact taatatgagt aaatctaacc 13021 taacgttaat attattattg cttattttaa caatcccctg attaatcaaa actgtttcgg 13081 ctgtgacaca ttcattttca ctaggattcc ctttaattct tcatatattt tcctatcgaa 13141 cttcaataac aaaatcccat atattacagt ccccactaca actggaatca atgttaacca 13201 cacattcgac agtggcatta accaccgata tccacccaaa aacaatccca taacaataga 13261 tgcctttaaa atattccaca aactgttaga ttccactctg atcgttagta tcttcgataa 13321 tacccatagt gccaaaactg tgtttagtcc cgtagtaata agggtggcaa ttgcagcccc 13381 taaaatccct attaatggga taaatgatgc attcaataca atgtttacca caactgaaac 13441 tacagtgatt ttaaataaat ctttaagata atccattgca gttagataag tagtgaaaaa 13501 aaaattaaat atactcacag tttgcacaat gaacaatact gccatagtca tatattctcg 13561 tccaaactcc gcaccgtaga aatagtacag gagtttatct cccagtaaaa atccacctac 13621 aagcattggt atggccacaa caagtgagta tgtaaacgct ctaggtaatg atttttctat 13681 caatctcata tcattggtct ttctccagcg gctaactctt ggatatagtg ttgatccaag 13741 tgcaactgtt gtgaacgaga ccagcaatgt aaattgcaat attatacggt acacacctac 13801 atctgcattg tcaagataat aacctatcat aactgtatct gcagtcgaaa agactatacc 13861 accacctgat atcaaaaaaa cccacaatga aaatgttgat aagcttttaa tgtgcctcca 13921 cctaaagcgc acaaaatgca aatcgaaaaa acgcagttga actatggaac tgacaactat 13981 ccctactaca aaaccaccgg caaggcctgc aacaccataa cccataaaaa tcgcaactat 14041 ttgaacaatt atgcgtgaaa agctattaat aaatcctgca gttgcactga ttcccatttt 14101 tccgcagcca ttgatgccac tttgaataac ccctcccaaa attcctacaa tcagcgacag 14161 tatgagccag ataaatattc cggaatcgtt gagattaaca aaataactgc gaaatgtaat 14221 taataccacc actaccaata tcacaaaaac agagcggagt acgataaaag cactgaaata 14281 cgcatcctgt tcctctccct cactgatgcg cttgattgca gctccaccaa agccgccgtc 14341 agccaccaga ttaatgatgc taagatacgc aagaaacagg aaatatccgc ccaacacgct 14401 tgcacccgcc gcatgtgcaa agtatattgt actcaagaaa ccaataaacg taagtgcaat 14461 ctgccagatg agagacgcta tgctctgacg tctgattgca tctatgctca taatgcgtga 14521 gacgaatgtt tctaatttga acatagttta tgtaatcctg tcgatgcttt agatatggac 14581 agattacagt tcataagtct ttcatatcct cttcaaccat cattttcacc agttcctgaa 14641 gtccgatctt agactcccac cccaacttct tcttggcttt tgttggattt ccaatcagga 14701 tatccacctc agtaggtcta taatatcttg gatccacttc aatcagaaca tcgcctgtag 14761 cagcatccat accgacttca tcaacacctt tgccctccca ttcaatttta atcccagctt 14821 ccttaaacgc aagctccaca aattcccgca cggaatgtgt ctcacccgtg gcaatcacaa 14881 aatcatcggg ttcatcctgc tggagcatga gccacatggc ttctacataa tctccagcaa 14941 atccccagtc ccgctttgca tcgagattgc ctagatatag tttattctgt agtccatttt 15001 tgatcttggc aacagccatc gtgatttttc gtgtcacaaa tgtctcgcca cgaattgggg 15061 attcgtggtt gaacaggata ccgttgcagg catacatccc ataagcttcc cggtagttta 15121 tggtaaccca gtaagcatag agtttggcta cagcgtatgg acttcttgga tagaaggggg 15181 tggtctcttt ttgtggaatc tcctgtacct tgccatatag ttcgcttgtt gatgcctggt 15241 aaaaccttgt tttcttctct aatccaagaa tgcgtatagc ttccaagaga cgtagtgttc 15301 ctactgcatc tgaatttgcg gtatattccg gggtgtcgaa agagatgtgc acatggcttt 15361 gggcggcaag gttgtatatt tcatcaggct gcgtttcctg aatgatcctt atcaaactcg 15421 cagaatctgt caggtcacca tagtgcagaa ataaatttac gtttttctcg tgtgtgtctc 15481 tgtacaggtg gtctatacgt ttggtattga aagacgatga tcgtcttctt atgccatgca 15541 cgatatatcc tttattaagc aaaaactccg caaggtatgc accatcctgt ccagtgattc 15601 cggtaataag agctgtttta gtcatttgag atacctcttt gtaataatga ttattcaacc 15661 tgtttgaaat actctatggt ttctcttagt ccgtcagcta acttaacctt tggctcccag 15721 cccaaaactt ctctcgctct ggtaatatca ggcctcctga ccttagggtc atccacaggt 15781 agttcctcgt acactatcct ggatacgctt ccggttattt ctatgatcct ctctgcaaac 15841 tccagtacgg tcatctctgc aggatttcct atattgacag gatccgtatg ctcagacatc 15901 ataagtctgt aaattccctc tataagatca gagacatagc aaaaagacct tgtctgcttt 15961 ccgtcaccgt aaactgttat atcttcacct ttgagtgcct ggttaatgaa attagggaca 16021 accctgccgt cgttagcccg catcctggga ccataagtat tgaaaatacg tgctattctt 16081 gtttcaatgc cgtggtgtgt gtggtatgcc atggtaatag cttcggcata tctctttgcc 16141 tcatcatata cgccgcgggg accgatgggg ttcacgttac cccagtaggt ttcaggttgg 16201 gggttcacca gtgggtctcc atacacttct gaagttgatg ctagcaggag tcttgcctta 16261 tgttcctttg caagaccaag catgttataa gtgccaagag cacccacctt cagcgtttgt 16321 atgggcaatt ccaggtaatc gacgggtgaa gccggacttg cgagatgaaa tatgtaatct 16381 atcttatcgc cgaaatagac aggttttgta atgtcgtgct ttagatacgt aaaattttcg 16441 aatctaatgt gttcgatatt ctttgttttt ccggtgacaa ggttgtcaat acatattacc 16501 ttgtgacctt tttctattaa caggtcgcag agatgcgaac ccagaaaacc tgctcctccg 16561 gttacaatcg atctcatatt atcacgcttt aaaactcaat agaggatgaa tccccgatat 16621 tcaaagaatt atgttttcct atgacgtttg cgtcatcacc gacaatggaa gattgaaggt 16681 tgacgctgga aaggtgcgtt cgcgaaccaa tgaccgtgtt cgatatgatc gagttctcga 16741 taaccgaatc ttctgcaatc gatgtgaacg gacctattac tgaattcact attttcacat 16801 ttgtcccaaa tataacaggt ggtattatta cggaacttat actatcatat acttcctgtt 16861 tactttcctg ttcgctgagc aatatcctgt tggcttccag aagcgatgtg gcatgcccgc 16921 agtcatacca gcttgacact tcaaacgttt tcagttcact gcctcttgaa accatttcct 16981 gaagtgcatc tgtcaactga tattctcctc tggtctttac accattctct atcatccact 17041 ccagtatatt cagaagaagc ggtgtgtcct taataaaata aacaccggca atcccaagat 17101 ttgaagatgg gttttccggt ttttcctcaa gcctctcaat atgggacgat tgctctttga 17161 ggtatactat accatatttc ctgggttctt caacttctct tacgccaatg gaagcagaac 17221 acgccccatt ttgacagtat tgatcatgga aatccttgta accggatttg aatatcatgt 17281 ccccaagggc tatcattgtt tcagagtccc ggatatgttc ctttgccagg tacacagagt 17341 gcccgagtcc catcctgttc tcctggcata catatcttat gttaaatata ctgctgtaat 17401 gtttatcaac atatgatatc agttgctctt ttcgatagcc cacaaccagt attatctctt 17461 caggatgaag gtctatcatt ctgtcaagta tgtgcccgat gattggttta cctgctatga 17521 ataccatggg ctttggtttt gtgtgcgtgt gagggaagag gcgtgttccg gcgcctgcag 17581 cgggtatgat gactttcatt tttatcctcg gttaacttct caaatatggt ataaatgcaa 17641 gccttctgtt taaatataat atttatttga cccttattat tttaaatgaa tataagggtt 17701 gtttcaggct ctcccatact catcatcaaa tctcacaata tcatcctctt ccacatactc 17761 gcccagctgc acttcaatga tctctagcgg gagtctccct gaattcgata gcctgtgctt 17821 cgagcccgcc ttgatgaatg tactctctcc ttgtctcagg aagaatttct ggccgtcgtt 17881 ctccacacac gccattcctt tgacgaccac ccagtgctcg ctcctgtgat gatggagctg 17941 caggcttagt ttctttccag gaaggaccgc tatgttcttt atcttgtgac cacctgagtt 18001 ttcaagcagc gtataggaac cccagggacg ataaacggtc tcatggatgt ttatacgctc 18061 gtcatttctc tttctgagaa agcctaccac ttctttaacc ttctcgctgc tctttcgggg 18121 gcatataagt aaggcgtctg tagtgtcaac aactatcata tcatttatat cgataagtga 18181 aaccagcttg ttagagttgg aatgcacaaa gttgttgccg gaatcgacaa atacattctg 18241 gcatgaaaga gtgcaattat tggacttatc cttctcccat tcagagtaga acgcgtcaaa 18301 attcccaagg tcgctccatt tacagccaag cctgacaacg ctgaccctcg aggatttctc 18361 catgatgccg taatcaatgg agatgttcgg catctctgca tatatttcct gtatcgtccc 18421 ggagttctcg aatgcattcc aaacatccgg ggctaattgc tgcacttctt ctaaaaagac 18481 ccctgtgtcc ataaggaaca tgccgctgtt ccagagacaa ccttctgaga tgtatctttg 18541 cgcatcttct tggcagggct tctccctaaa ctctgaaacc ttgtgaccga tctcaagctc 18601 ctctccgggc ttgatgtagc catatccggt atgtggggaa gagggagcta tcccgaaggt 18661 caccatgtat ccggaggtca acttctctgc accggaaatg gtttccattg cgattgggtc 18721 aagcacatga tctgaagaga agacgccgac aactgacctt ccatgtgctt tatctatttc 18781 cttcatcccg taacatatag cggggagcgt attctttcct tcgggctcaa ggagaaggtt 18841 ctcaacaggt aggtcataac caagctcttc cacctgcccg atcgcaaaat acttgtggac 18901 ctcatttgta acgacatata tctctgatat gtctgacact tgcaggcatc ttaatactgt 18961 atcctggaaa agggacctgt cctttatctt caggaactgt ttaggataaa gttcccggct 19021 aagtggccat aggcgtgttc ccgatccgcc tgcaagaatt attgacttta tacacattcc 19081 tccgctttaa ctaactggaa attgtttgct ttgtgtgaac taccatccta tgaataggat 19141 ggcttcctgc ttcattcttt ccccttgtga ggacaagtcc acaggctcat tccgtagttc 19201 ctacggtgtt atattctaat taagttttgc ttatcaagtg caaacttttt gatattaata 19261 gcggcattaa tatctcgatc gtgattggtt ttacaatccg gacattgcca ttttctgttt 19321 gcaagtgtta atttaccgtt gtgataacca cacatattac agattttagt cgatggctcg 19381 aattgtccta tacggagtat tgttttacca aaccattctg ccttatattc cagcttggat 19441 acaaaagaac tccaagaagc atctgctatg tgcaatgcaa ggcaatgatt tttcaacata 19501 ccgctaacgt ttaaagtttc caatgctaat gcttgattct cacctatcag cttagaggat 19561 aatttatgtt gaaaatcatt tctttggttg cttatctttt catggagttt tgatacttct 19621 aatctggctt ttgctctgtt ctttgaacca ttttgctttc gactcatcct tctttgaagg 19681 gcattaaggc gttctaatga tgttttaagg tattttggat tatctatttt ttcaccattg 19741 gaaagaactg caaagtcctt gattccaaca tcgataccaa cagttacctt ttcgttgaac 19801 agacttttaa cgggtgtttc ctgtttatca tctacaagaa tgctgatgta atatcttcca 19861 gttgatgttc cggatacagt agctgttttt tcaataccct taaatttacg atgtagtttt 19921 gtttttatcc acccaatctt aggaagtttt attttattgt tatcaaaatc cacttcgtag 19981 aattgaggta ctgaaaaaga ttgtacttga ttctttttag atttaaaagt aggaaatccc 20041 tttttctctc taaaaaattt agtaaaagca ttttcaagat taagagtagc accctgcaac 20101 gattgggaat ttacatcctt caaccattcg tgttctactt tcaaaccagt tatcatttta 20161 ttcaaggtga atcttgatac tgatttacta tcttgttgat atgacttgat tttgtgttct 20221 aaagcccaat tatagacaaa cctacatgca ccaaagtgtt gatagaacag ctcttcctgc 20281 tcttttgtag gatatattct gtacttatag gctttcaaca tacaaacata tatccaattt 20341 aatatcattt ataattagtg ttaaatcgtg gaaagaacat gttttgcagg atagacgtaa 20401 ttcatccccg tttgaatata gtggtctttt taatcaaacg tgataatcgg acaagtcata 20461 gtccttttcc tactgctcct acttaaatct taagtactag aactctaatc atatgcacta 20521 tttctatcaa taattatcaa tccctaacag gtgatcacat gtcatataca attcttgaaa 20581 agaagcagat agcgccccag gtgcatctga tgaaggtgct ggcaccggat gtagctaagg 20641 ctgcaaaggc aggccagttc attattttgc gcatcgatga aaccagcgag cgcatccctc 20701 ttacaattgc tgattttgat accggtgaag gttacgtcac aattatcttc caggaaatgg 20761 gtaaaaccac aaagcaacta gcaaaaatga gcaacacgga tgtactgcag gactttgtcg 20821 gcccgctggg gaaacctgcc gatgtgcaaa aactgggtac ggttatactt gtgggaggag 20881 gcgtcgggat cgccccagtg tatccgcagg tcaaagccta ccgtgaagcc gggaacaagg 20941 tcatatccat tattggtgca aggaacaagg acctgctcat actggaagat gagatgcagg 21001 acgcaagcga tgaactttat gtggctacag atgatggctc caaaggccac catggttttg 21061 tgaccgaagt cgcaaagaag atccttgaca gcggcgagaa gatcgcaagg atagttgtta 21121 tcggtcctcc catcctgatg aaggtggcag caggcatgac agctccatat ggtgtggaaa 21181 ccatcgtcag cctgaacccg ataatgatag acggcacagg catgtgtggg ggctgcaggg 21241 tctctgttga cggcgagaca aagttcgcct gtgtggacgg gcctgagttc gatgcacaca 21301 aagtcgattt caacctgctt atgagccgcc ttggccttta caggagcgaa gaggcgcagt 21361 gtcaggaaga tcacaactgc acctgcagga gtggtaactg atggcagcaa gacagccaat 21421 gcctcatcag gacgccaaag agcgggcccg gaatttcgat gaggttgcac tgggatatac 21481 caaagagcag gcaatcgctg aagcttcacg ctgccttgag tgcaggaatc ccaaatgtgt 21541 ccaaggctgc cccgtgaaca ttgatatccc tggttttatt gcacagataa aaaccgggaa 21601 cttcgatgag gccatcgcca ccatcaagct gaccaattcc cttgcagctg tatgtggccg 21661 cgtctgccct caggaagtgc agtgtgaaga gttgtgcgtg cttgcaaaga agggtgagcc 21721 ggtggctatc ggcaggcttg agcgcttctg cgctgatcat gagcgggaaa agggggtagt 21781 tcctccggtg cgcacccagc caagcggcag gcgcgtggct gtcatagggg caggtccagc 21841 agggcttact gcggcagcgg accttgcaaa ggcaggccat gctgtcacca tctttgaggc 21901 acttcatgac acaggaggag tcctgacata cgggatacct gagttcaggc ttccaaagtc 21961 tatcgtgcag gaagaggttg attacataag gcagttaggt gttgatttca aggtcgacta 22021 tgtcatcggg aagataaaga tccttgatga gctgaggaac gatttcgatg caattttcct 22081 tggcacgggt gccggtcttc cgaaattcat gggcatcgag ggcgagaacc tgaatggcgt 22141 ttactctgct aatgagttcc tcacaagggt caacctgatg aaagcttatc tcttccccta 22201 tcatggtact cccgtcaaga gaggcaagaa agttattgta gtaggtggcg gcaatgttgc 22261 aatggatgct gcgcgtagtg cgcttcgcct tggagccgaa gaggttagta tcgtctatcg 22321 ccgtggagag cacgagcttc ctgccaggaa ggaagaggtc gagaacgcaa aggaagaagg 22381 cgtagtattc agacttctca ccaatcctgt ccgcatcctg cagggtgaga acatgaccgt 22441 aaaaggtgtc gaatgcatca ggatggagct tggcgagccg gatgagtccg ggcgcaggag 22501 ccctgttgtg aaagaaggtt ctgagcatgt gatcgatgca gatattgtta tcattgccat 22561 aggcacatcc cccaatccga tgatactgtc cggctcagat gggctgaagg taggggcacg 22621 tggcaatata atcgtagatg aatccgcaag gacatccctt gaaaacgtct gtgcgggagg 22681 ggatgcagtg acaggcgcgg caaccgtcat cagtgcgatg ggagccggca agcttgcagc 22741 ccagactatt aatgaatacc tgatgaataa ctga //