LOCUS NC_017353:4 22165 bp DNA linear BCT 05-SEP-2013 DEFINITION Staphylococcus lugdunensis N920143, complete genome. ACCESSION NC_017353 SOURCE Staphylococcus lugdunensis N920143, complete genome. COMMENT locus start: 505935; locus end: 528099 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.609605; n0_4mer:D = 24.692364; n0_4mer:PS = 38.275064 FEATURES Location/Qualifiers source 1..22165 /organism="Staphylococcus lugdunensis N920143, complete genome." gene 1..1488 /gene="xylB" /locus_tag="xylB" /db_xref="505935..507422" CDS 1..1488 /gene="xylB" /product="xylulose kinase" /translation="MQEVVLGIDLGTSAVKIIAVDKEGQVLVTVSEPLTLIQQQPGYN EQDPDEWLDAVKQGIKRVTQHDSLKHHTIQGISFSGQMHGLVPLDKNGCPVRHAILWN DTRNSAQCEQIIARYGQRLNGNPILEGFTLPKMLWMQQHEPELWKHVDTFVLPKDYIR YGLTGQIHMEYSDAASTLLLNPTTHEWTREIGDAFGLGEIYPPLIPSHGYVGNVKSGL AIELGLTSNVKVFAGGGDNACGAIGAGVVNDNDTLCSIGTSGVIVNVEKDEHTQYQNN IHFFNHSVPNTYYAMGVTLAAGYSLSWLKHTFFAADSYDDVIKLAASSSIGANRLLYT PYLAGERTPHGDAFIRGSFIGLSGSHTKADFSRAVIEGVTYSLYDSIQLMRAAGKEIT HVTSIGGGAKSEFWLQLQADVFNTTVRKLKHEEGPSMGAAMIAAVGLNWFESIEDCVD AFIDIVAEFHPNPEWHRQYEQFYQIYQQVYAQTRTITQQLLTLEI" gene 1974..3017 /gene="" /locus_tag="" /db_xref="507908..508951" CDS 1974..3017 /gene="" /product="hypothetical protein" /translation="MNIILGVGTLVLVLAVMTLFLKYAPYGKQGLQALSGAACATFLP QAFLSYAIGGVFHIEFLKEIGDLVGGLSGVAVGILTCLKLNISPVFAVIVGLVLHDYK LLPAFIAAYIMAFGIKLIEKKVPEGLDLIVVILVAPAITFGLAHIISPGVMAVLRQIG GAVTSVGDNNPYALAIILGLVIPVTGMTPLSSMVLTSLLGLTGVPMAIGALTCMGSSF VNFVLFRTLKIGGPSKAFAVCIEPLTQIDLIAQYPLQLYGTNAIIGMVNACIVTFAGL VINVTGMATPIAGAIVLFGFNKPLPSVITIIVVAVVSIILAYIFGKLISKLNITKTDI TIPGQNNQVKESV" gene 3020..3700 /gene="" /locus_tag="" /db_xref="508954..509634" CDS 3020..3700 /gene="" /product="putative L-serine dehydratase, beta chain" /translation="MAKKSYDYQSAFDIIGPVMMGPSSSHTAGAVKIGNSAGSVLGVT PQKIEIRYYESFAETHQGHGTDVAVIGGAMGYSTFDSRIKDALNIAESQGIKVDIIED RGESLGEHPNCAYIKAEANGRHIEVIGNSIGGGTIKLKRINVEGLEVNFNHGLPILVM DGYTDKSTVNHFINFASEAGAAIDKEMTEMKDNQCLVVLPLSKALSESALEQIREKYS DLNVSYIN" gene 3714..4610 /gene="" /locus_tag="" /db_xref="509648..510544" CDS 3714..4610 /gene="" /product="putative L-serine dehydratase, alpha chain" /translation="MFDSIRETIDYAVENDMSFADIMINEEMELQGKSREDVRAIMKQ NLEVMRAAVEKGTTGEGVKSVTGYTGQDAIKLNKYNESQHALSGHEMIEAVKGAVATN EVNAAMGIICATPTAGSSGTIPGVLFKLEKTHDLTEDQMIDFLFTSALFGRVVANNAS VAGATGGCQAEVGSASAMAAAAAVAIFGGKPEASGHAMALAISNLLGLVCDPVAGLVE IPCVMRNAIGSGNALISADLALAGVESRIPVDEVIEAMDKVGRNLPASLRETGLGGLA GTSTGEAIKRKIFGDAEKKVNN" gene 4806..4982 /gene="" /locus_tag="" /db_xref="510740..510916" CDS 4806..4982 /gene="" /product="hypothetical protein" /translation="MRRLFGIFLAFTINTTMTYYLTTEGTWENLLLQCMSLSMIIVFF FYYFQFIKKAKKMT" gene complement(5113..5607) /gene="" /locus_tag="" /db_xref="511047..511541" CDS complement(5113..5607) /gene="" /product="acetyltransferase (GNAT) family protein" /translation="MIRHAERQDLPAILSIYNDAIINTTAVYSYESQTIEEREEWFER KVIAGEPILVFEQHQQVVGFATYGSFRDWPAYLYSIEHSIYVDSAYRGHGIASQLLSQ LMQIAKDEGYRTMVAGIDASNEVSIHLHEKIGFIHAGTINNVGYKFNRWLDLAFYQID LLIK" gene 5758..6363 /gene="srtA" /locus_tag="srtA" /db_xref="511692..512297" CDS 5758..6363 /gene="srtA" /product="sortase A" /translation="MRKWTNQLMTIIGVILILVAIYLFAKPHIDSYLHDKDNSDKIEN YDKTVSKANKNDKPTIPKDKAEMAGYLRIPDADINEPVYPGPATPEQLNRGVSFAEEQ ESLDDQNIAIAGHTYIGRPHYQFTNLKAAKKGSKVYFKVGNETREYKMTTIRDVNPDE IDVLDEHRGDKNRLTLITCDDYNEKTGVWEKRKIFIAEQIK" gene 6563..16943 /gene="slsE" /locus_tag="slsE" /db_xref="512497..522877" gene 17139..17936 /gene="" /locus_tag="" /db_xref="523073..523870" CDS 17139..17936 /gene="" /product="putative haloacid dehalogenase-like hydrolase" /translation="MIKAIAVDMDGTFLDSQKHYDEVRFNQQFQKLQDKNIKFIAASG NQYAKLRSIFGDKEMYFIAENGAVIYQGNSLYDYKSFDIQDYQSLVQYLMLEQGLREF IICGLKSAYILKDTSQPFKENAHFYYHQLEEIDSFNVLPDDDYVKIAFNINRTTHPTL DEDMAIRFKYIASLVSSGHDSIDVIMPSMTKGEALKGLLTKWHIKPSELMAFGDANND KDMLALAHYSYVMANSNDSELFDIAHAVAPSNDEQGVLQVIDDVVLS" gene complement(18061..18543) /gene="" /locus_tag="" /db_xref="523995..524477" CDS complement(18061..18543) /gene="" /product="transposase" /translation="MSSDTNSLAHTKWNCKYHIVFAPKYRRQVIYGKIKKDIGMILRQ LCERKGVEIIEAEACKDHIHMIVSIPPKIGVSSFVGYLKGKSSLMIFDRHANLKYRYG NRKFWCKGYYVDTVGRNKKVIENYIRNQLQEDIVADQITMEEYLDPFTGEEIKKRKKK" gene complement(18741..19733) /gene="ddh" /locus_tag="ddh" /db_xref="524675..525667" CDS complement(18741..19733) /gene="ddh" /product="D-specific D-2-hydroxyacid dehydrogenase" /translation="MTKIMFFGTRDYEKKDALNWGKAHNVEVVTSEEILSADTVDQLE GFDGVTTMQFGKLEDSVYPKLEGYGIKQIAQRTAGFDMYDLDLAKKHGIVISNVPSYS PETIAEYSVSIALQLVRKFPLIEKRVQAHNFKWAAPIMSTPVKNMTVAIIGTGRIGAA TGKIYAGFGAKVVGFDAYPNHSLDFLEYKDSVEEAIKDADIISLHVPANKESFHLFDK SMFSKVKKGAILVNAARGAVIDTPALLDAVNDGTLSGAAIDTYENEADYFTYDWTGKD VDDPTLLELIRHENILVTPHIAFFSDEAVRNLVEGGLNAALSVIETGKCDTQLN" gene 20087..20746 /gene="" /locus_tag="" /db_xref="526021..526680" CDS 20087..20746 /gene="" /product="nitroreductase family protein" /translation="MSQMNETIINALNFRHATKIFDSSKQVSDKDMQTILESGRLSPS SLGLEPWRFVVIESQELKDKLKPYSWGAQKQLDTASRFVVILARKNVTAQSDYVQHIL RDIKKYDTHTIPAVEQKFNDFQTNFHINDSERTLLDWASKQTYIALANMMTSAALLGI DSCPMEGFDLDKVTEILQDEGVIDTVHFAPSVMVAFGYRKDEPKGKVRQPATDVIEWV K" gene complement(20944..21777) /gene="slsB" /locus_tag="slsB" /db_xref="526878..527711" CDS complement(20944..21777) /gene="slsB" /product="putative LPXTG cell wall-anchored protein" /translation="VKFYQQQRFGIRKFAIGIGSVALATVVFLGANQDAYASETSRTA TEQNQSQAQHQANTQNQHTSGKHTSEVDITSPYGKTTDIIEKNNSNQNSSSHSKTEII LGSTDGEWLINDITIINSETHHTSQNNHSSHNIKTEKQSTSKKIQHTGSSVKTVSQQR TSQSRLTKQAVQHQSQKQNVEKHSKIVNPSTAAVNVEQPFNPSQHNELNHTHQTLINQ TKKPTVTHATSSNMTVTAPITHKALPNTGKEETPEHSMALASILAVLGSALFMRRRKH I" ORIGIN 1 atgcaagaag tcgtattagg tattgattta ggtacgagtg cagtgaaaat catcgcagta 61 gataaagaag gacaggtatt agtaaccgtt agcgagcctt taacattgat tcagcaacag 121 ccgggatata atgaacaaga tccagatgaa tggctagatg ccgtaaagca agggattaag 181 cgcgttacac agcatgacag tcttaagcat catacaattc aagggatatc attttctgga 241 caaatgcatg gcttggttcc tttggataaa aatggttgtc ctgtgaggca tgcaatctta 301 tggaatgaca cgcgcaattc agcacaatgt gaacaaatca tcgcgcgcta tgggcaacgt 361 ttaaatggta atccaattct tgaaggcttt actttaccta aaatgttatg gatgcaacaa 421 catgagccag agctatggaa acatgtggat acgtttgtat tacctaaaga ctatattcgt 481 tacggtttaa ccggtcagat acatatggaa tactctgatg cagcaagtac attattactt 541 aatccaacaa cgcatgagtg gacaagagaa attggagatg cctttggttt aggtgagatt 601 tatccaccat taataccatc gcatggttac gtcggtaatg ttaagtcagg attagccata 661 gaactaggat taacatcaaa tgtcaaagta tttgctggag gcggagacaa tgcgtgtggt 721 gcaattggtg ctggtgtagt taatgataat gacactttat gtagcattgg gacgtctggc 781 gtgattgtca atgttgaaaa ggatgaacat acacaatatc aaaacaacat tcacttcttt 841 aatcatagtg tgccaaatac ttattatgca atgggagtaa cattagcagc aggttacagt 901 ctttcttggt tgaaacatac gttttttgca gcggatagtt atgatgatgt gattaagtta 961 gcagcctcat catctatcgg tgcgaaccgt ctactttata ctccctattt agcaggtgaa 1021 cgcacaccac atggagatgc ctttattaga ggaagtttta ttggtttaag tggcagccat 1081 acaaaggcgg atttttctcg agcagttatt gaaggtgtga cgtattcttt atatgattca 1141 atacagttaa tgagagcggc gggtaaagaa ataacgcatg tcacttctat tggcggaggt 1201 gctaaaagtg agttctggtt acaacttcaa gcagatgtct ttaatacgac tgtaagaaag 1261 ttaaaacacg aagaaggtcc tagcatggga gctgctatga tagcagcagt aggtctaaat 1321 tggtttgaga gtattgaaga ctgtgtcgat gcatttatag atatcgttgc agaatttcat 1381 cctaatccag aatggcatcg tcaatacgag caattttatc aaatatatca acaggtatat 1441 gcacaaacaa gaacgattac acaacaacta ttgactttag aaatataaaa ttaagcaaga 1501 gtctagggca tcattatgat ttatgttcta aactctatat tggtagcagt tgactggatt 1561 gaaaatacgc ttatactaag ttttttcaat tctagtcgac cttgccgggg cgggacgacg 1621 aattcataat gaattctctc ccgttccttt tttgtgatta aatcgtgagc attttaaaac 1681 aaaaatattt aagtatacgt tacgataaag atatgtaaag ttagtgtata tatatgaaga 1741 attatgtata aaattttact tgttgcaatc aagttcttca tggtgtaaaa tgttaaaaaa 1801 taaatttaat cgttacaata atttaaataa cacaatttta gaaacgcgaa aatttgcata 1861 ttgtgaatat attcacattt tagactaaat aaaattttgt tttatattga aatcgttttc 1921 ttaggggtgt acgatgacta tggctagaaa aaattgaaaa gaggttttgg gaaatgaaca 1981 ttattctagg cgtaggtaca ctcgtattgg tgttagcagt gatgacactg tttttaaagt 2041 atgcaccgta cggtaaacaa ggactacaag ctttatccgg agctgcttgt gctacatttt 2101 taccacaagc attcctgagt tacgctattg gcggcgtatt tcacattgaa tttttaaaag 2161 agattggtga tttagtcggc ggtcttagcg gcgtagctgt aggtatttta acgtgtttga 2221 aattaaatat atcacctgtt tttgcggtga ttgtagggct agtcttacat gattacaaat 2281 tattacctgc atttattgct gcgtacatta tggcttttgg aattaagctt attgagaaaa 2341 aagttccaga aggtttagat ttaattgttg tcattctagt tgcacctgct attacgtttg 2401 gtttagcaca tattatttca ccaggggtta tggcagtatt aagacaaatt ggtggcgctg 2461 ttacttcagt tggagataac aacccatacg cattagcaat tatattagga cttgttattc 2521 cagttacagg aatgacacct ttaagctcta tggttttaac tagtttatta ggactcactg 2581 gtgtgccaat ggcaatcggt gcattaactt gtatgggcag ctcatttgtt aactttgtct 2641 tatttagaac attgaaaatt ggtggaccat caaaagcatt tgcggtatgt attgaaccac 2701 ttacccaaat tgacttaatc gcacagtatc cattacaact ttatggtacg aatgcgatta 2761 tcggtatggt caacgcatgt atcgttacat ttgcagggct agtgataaat gtaactggta 2821 tggcaacacc aatcgctggt gccattgtat tgtttggctt taataaacct ttaccatcag 2881 ttattacaat tattgtggtt gcagttgtaa gtattatttt agcgtatatc tttggtaaat 2941 tgattagcaa attaaatatt acaaaaacag acatcacgat tcctggacaa aacaaccaag 3001 ttaaggagag tgtttaataa tggctaaaaa atcctatgat tatcaaagcg catttgacat 3061 tattgggcca gttatgatgg gaccatcaag ttctcatact gctggtgccg ttaaaatcgg 3121 taactcagca ggaagtgtac ttggtgttac acctcagaaa attgaaattc gttattacga 3181 atcatttgct gaaactcatc aaggtcatgg cacagatgtc gcagttatag gtggtgcgat 3241 gggctatagc acgtttgata gccgtattaa agatgcttta aatattgctg aaagtcaagg 3301 tatcaaagta gatatcattg aagacagagg cgaaagcttg ggagaacatc caaactgtgc 3361 gtatattaaa gctgaagcaa atggtcgcca tattgaagta attggtaact caattggtgg 3421 cggaacaatt aaactaaaac gtattaacgt tgaagggcta gaagttaact tcaatcatgg 3481 attacctatt ttagtgatgg atggttatac tgataaatcc acagtcaatc atttcattaa 3541 ctttgccagt gaagccggtg ctgcaattga caaagaaatg actgaaatga aagacaacca 3601 atgtttagta gtattacctt tatctaaagc attgtcagaa tcagcgttag aacaaataag 3661 agagaaatat agtgacttaa acgtatccta tataaattag agggggattt ataatgtttg 3721 attcaattag agagacaatt gattatgcag tagaaaatga tatgtcattt gctgacatca 3781 tgatcaatga agaaatggaa cttcaaggca aatcacgtga agacgttcga gcaattatga 3841 aacaaaatct tgaagtaatg cgcgcagcag ttgaaaaggg cacaactggt gaaggcgtaa 3901 aaagtgttac aggttacaca ggtcaagatg caatcaaatt aaataaatac aatgaatcac 3961 aacacgcttt atctgggcat gagatgattg aagcggttaa aggagctgtt gcgacaaatg 4021 aagtgaacgc agcaatgggt atcatctgtg caactccaac agctggctcc tccggaacga 4081 ttccgggcgt actttttaaa ttagaaaaaa cacacgattt aactgaagat caaatgattg 4141 atttcttgtt tacttcagca ctgtttggcc gtgttgttgc aaataacgcc agtgttgcag 4201 gtgctacggg tggttgccaa gccgaagtag gatcagcatc agcaatggca gctgcggcag 4261 ctgtagccat ttttggaggt aaaccagaag catctggaca tgctatggca ttagcaatta 4321 gtaacttatt aggattagtt tgtgacccag ttgcaggctt agttgaaatt ccatgtgtaa 4381 tgagaaatgc cataggatct ggtaacgcat taatttcagc agatttagca ttagcaggtg 4441 ttgaaagtag aattcctgtt gatgaagtta ttgaagctat ggataaagtt ggtagaaact 4501 taccagcatc tctaagagaa actggacttg gtggcttagc tggaacatca acaggagaag 4561 cgattaaacg taaaatcttc ggagacgctg aaaaaaaagt caataattaa attctacgaa 4621 aacctagatt ataacatttt agggagtggg actacgaatt cataatgaat tctgtcctgc 4681 tccctttttc atggatattt accacaattg attacataga agtggagtca attttccgaa 4741 aatttaaaat cttatattgc aaatttacaa ctttgattat aaaatatcca aaaggggttg 4801 atgttatgcg aaggttattt gggatttttt tagcctttac gattaacaca acgatgacct 4861 actatttgac aacggagggt acatgggaga atcttctatt gcaatgcatg tcgcttagta 4921 tgataatcgt atttttcttt tactatttcc aatttattaa gaaagctaaa aaaatgacat 4981 agttgaataa taaaagcgct cgggaaatga aacttgagcg cttttattgc tatagtaacg 5041 agtctatgta cggttataaa ttaatatcaa agtgatgaca aaatttatta gacttaaatg 5101 ttaatatttg aattatttaa ttaataaatc aatttgataa aatgctaaat ccaaccaacg 5161 attgaatttg taaccaacat tattaattgt acctgcatga ataaaaccaa ttttttcgtg 5221 tagatgaatg cttacttcat ttgaagcatc gatacctgca accattgtac gatagccttc 5281 atctttagca atttgcatta gttgactaag taattgtgaa gcaataccat ggccgcgata 5341 ggctgaatct acataaattg aatgttctat tgaatagaga taagcaggcc aatctcggaa 5401 tgaaccataa gtagcgaacc caacgacttg ttgatgttgt tcaaatacga gaataggctc 5461 tccggctata acttttctct caaaccactc ttcacgttcc tctattgttt gtgactcata 5521 gctataaaca gctgtcgtat tgataatagc atcattataa atagatagaa tggccggtaa 5581 atcttgacgt tctgcgtgtc taatcatatg tctcaccttt ttatttttta ttgtatagtg 5641 ttcaactatt gatttcaaat ttatgtaata aaatatgaca aacttgtcgt aggtaaaaaa 5701 agcaatcaat gctatactat tatcaaacaa ttttacggtt taaaggagaa atactgcatg 5761 agaaaatgga caaaccaatt gatgaccatt attggagtta tacttatatt agttgccatt 5821 tacctatttg ccaaacctca tattgatagt tatttacatg acaaagataa tagcgataaa 5881 atagaaaact atgataaaac agtcagtaaa gcaaataaaa atgataagcc aaccatccct 5941 aaagacaagg cagaaatggc tggttatctc cgtattccag atgctgatat taatgaacct 6001 gtttaccctg gaccagcaac acctgaacaa ttaaaccgtg gagttagctt tgccgaagaa 6061 caggaatcct tagatgatca aaatattgca attgcaggtc atacatatat tggccgccca 6121 cattatcaat ttacaaattt aaaagcagct aaaaaaggta gcaaggttta ttttaaagtg 6181 ggaaatgaaa caagagagta taaaatgaca actatacgag atgtgaatcc agacgaaatc 6241 gatgtgctag atgagcatag aggggataaa aaccgcctaa ctttaattac ttgtgatgat 6301 tataatgaaa agacgggtgt ttgggaaaag cgtaaaatat ttatagcaga acagattaaa 6361 taattgtaga acactttgat ccgttagtta ttaactaata gattgaagtg tttttttatt 6421 ttctctcaca atatgatttt aagcaaaatt caaagtacaa aaaatgatat aaaaaaataa 6481 tagtattgtt atacgctgaa ttatctgata ttcttagtgt agataaatac atcaagatta 6541 tacaacgagg acgtgacaaa aagtgaaatc aaacaaaaaa ccagctcaat ttcttaatcg 6601 acataacaat tattcgatta gaaaatttac aattggtact gcttctattc ttgttgggac 6661 aacattgatt tttggtttga gtaatgaagc acacgcccaa agcaatagtt cagcaaaggt 6721 atcagataag gtagcaactg aacagtcagc atcgacttct caagaggcag atagcagtca 6781 acaaactgca gcttctaatg ctcaaaacgt tcaaactgca cctgagcaag ataaagcaac 6841 acctactaca gaggttaact ctaacaataa tcaaacagat tctaagcacg tagcaccaca 6901 gaaagagcaa aatcaaacag ctacgcaaac agaatctaaa aaagaaactg cacaaacaca 6961 agcaaaaaca gaagaaaaag cagcttctga tagcaaaaaa gcatcagaag attcagatga 7021 taaagcgact tcaaaagaaa cagatgaaaa taaaactgat gatagtgtag atacaaactc 7081 taatatcact actccagtgt atgatacgac acgtgcgcgt gctgcaactt cagtaccact 7141 tgctagtagt cttgactcag atgctagtgc tgctgaaaat gcagagccac cagcagaatt 7201 tattgataaa tacaataaat caacaaatag aagtcaatta gtgcatgatt tattagctga 7261 atcatacagt gaaacagacg ttagagcaat tgttaatcgc ttaaatatag actttaataa 7321 gacagatgct aaaaaagcat ttcaagcgat aatgtatgct ggtattcaat atgctaaaga 7381 acaaacatca ttatacacaa catatgctac tatacctggt gatggtgtaa atgttaataa 7441 cacagaaatt ggatcggtag cagagttaaa gcgtagtatt tatatagatc caaataaagg 7501 cttaacagtt aacggtcaag gatatacttc tcaaggccaa tctcctgcaa actatacagt 7561 acatgttcaa cctaataaaa gaacaaataa aatggacttt actgtaactt ggaaagttaa 7621 tccatcagct tctgcatctg ggcatgacgc tgatttaggt ggctttaact ttggctcagg 7681 atataatgtg ccagaacgta ttaacggtcg ttttaatata tatggtggta atacaatctc 7741 aaataattta gatatgatta aaagtccaca ccctagttat ccagctggtt atggtttgag 7801 tagccgacca acaattacga gatattttgt tcaacgtggt ggacgtgtag aatatcattt 7861 tagtgttcca gtacgtgatt ggaatggtga tttaagcttt aatggtaagg ttctaatgtt 7921 cgacaacaac gttactcttg ttggtcaagg tgtaatgaac ccaaattcaa atgataacta 7981 cttctatgac gaaatgaaca tccagggaga taataatcca gatcgtcata ttatcactac 8041 tgatgatacg tcagaagttg aaaatattcc tttccaaata gaatacgtgg tttctaaaga 8101 cttacctgta ggtcaacaag aagttcaaag agaaggtcaa gtaggtaaac gcggtacact 8161 ttattcaatt gttaaattta ataaccaaac aattggtcga tttgttaaag aaacatacaa 8221 tataccacca gttaataaaa ttattaaaat tggtattggg gctgtaaatg attctaatat 8281 cagtggacca ctacctccaa ttcttgaacc acaactttct ggtacaaata ttgttagcgg 8341 tgaaacaagc cctaatgctg ccgtaacaat aacagtagga ggaagaaact atcaaacgac 8401 atctgataat tcaggtcgat ttaatttcca attgccaaat tatacattgc aagaaggaga 8461 ccacatttca gccgtagcaa ctgttgaagg taaaacaagt aaacctggaa aaattattat 8521 tcctcgagat ggtagaacac ctaaccttac tacatcagtt caacgtggac aagatcaaaa 8581 taaaccaggt agttgggtaa caattacgaa tgcgacaact ggtcaacaag taagtcgatt 8641 ctttgtacca gatggtttac ctggtaatga tggtcgttct attactatta caaatgaata 8701 tttagatcca agtactggag aaagagtcgt tcaatttagt gacggacgaa caatccgtct 8761 tcctaaagga ccaaaaggtg ataaaggtga ccaaggtcca gcaggtaaat ctattactgt 8821 caaacacata tctaaagatt cacaaggaaa tacaacagtt caatttagtg ataattcatc 8881 tattatcatt ccagcaggta cgcctggacg taatggtact tcagtaggaa tacgtacaat 8941 tacgccgcaa gcaaatggcg atacagttgt aacgtttaca gatggtaaaa caatgacaat 9001 accaaaaggt gccaaaggtg atcgtggtga agctggtcca aaaggtgccg atggtcattc 9061 aattacaatt acaagcaata cggtagaacc aaatggtgat cgtaaaattg ttttctcaga 9121 ccacactacc gtagtaattc caaaaggcga caaaggtgat aaaggcgaca atggtacatc 9181 aataggtatt acccaaattg atacagacgc agcaggtaat aaagtcgttc attttacaga 9241 tggcaaaaca atgacagtac caaaaggtca agatggtaca tcaattggaa tcaagtctat 9301 tacgccacaa gcaaatggcg ataaattagt aacatttact gataatagaa ccatggtaat 9361 tccaaaaggt gacaaaggtg acaaaggtga taaaggcgac aaaggtgctg atggtgcgag 9421 tccaaccgtg acagctacac gtacgcaaca tgatggaaaa gatggtgtgg aaatcacgat 9481 tacccctgca aatggtggta caccaattaa aactttcgta gctgatggtg aacgtggtga 9541 gagaggtctg caaggcatta acggtgtaga tggaaaatct atccgagtat caagtagccg 9601 tgataatcaa aaacatgaaa caacattgac cttctattac gatcaagatg gcgatcaagc 9661 ctttgatgca agtaaagaca tcgtagttga cacagctgtt atcaaagatg gtcgtacccc 9721 aacggtagat attaagaaaa ttttacgtgg tgtgtcaaca tttagaactg ccacagctac 9781 cgcgaatcct gataaaggtc atgaagtcaa attctattat gacaataaca acaacggtat 9841 ttttgatgaa ggtgatgaag aaatttcatc tggcttcatt gctgatggta aaaacggtca 9901 aaatggtcga aatggacgac aaggtactga attaataagt ggaataacac ctcctacaga 9961 tagtgatggt ctaaatggcg atacgtatat cgacactaac actggcgaca cttataaaaa 10021 agaaaacgga aaatgggtgc caagtggaaa tatcaaagga ccaaaaggtg acaaaggtga 10081 gaatggtcaa aacggtagag atggaaaaga cgttctgaac ggcaaagttg atccacaatc 10141 aagtcaaggt aaagatggcg ataaatacat caatacagta acaggtgatg tctttgttaa 10201 atcaggtgac aactggacca acgaaggcaa tatcaaagga ccaaaaggtg acaaaggcga 10261 taatggttta aacggtagag atggaaaaga tgttctgaat ggcaaagtta atccacaatc 10321 aagtcaaggt aaagatggcg ataaatacat caatacagta acaggtgatg tctttgttaa 10381 atcaggtgga aactggacta atgaaggtaa tatcaaagga ccaaaaggtg accgaggcga 10441 acgtggtgag actggtccaa aaggtgataa aggcgaaaat ggcacatcaa ttggaattac 10501 aacaattgac acggattcag ctggaaataa agtcgttcgc tttacagacg gcaaaacaat 10561 gacaatacct aaaggtcaag atggtacatc aataggtatc cgtacaatta caccacaaac 10621 aaacggtgac acagttgtaa cctttacaga cggtaaaaca atgacgatac caaaaggcgc 10681 taaaggcgac aaaggtgata acggtcgtga tggtacatca ataggcatta caaatattca 10741 aacagatgct gcaggtaata atattgttca ctttacagat ggtaaaacaa tgacagtacc 10801 aaaaggtcaa aatggtacat caataggcat ccgtacaatt acaccacaag caaatggtga 10861 catagtcgta accttcacag atggtaaaac aatgacgata ccaaaaggtg cgaagggtga 10921 taaaggtgac gtaggtgcac gaggtgcaga tggtcgctca atcacaatca caagtaatac 10981 agaacaacca aatggagatc gtaaacttgt gttctcagat aacactactg tcatcattcc 11041 aaaaggtgca aaaggggata aaggcgacaa aggtgataat ggtacatcaa ttggaattac 11101 aacaattgac actgatacag ttggcaataa agtcgttcac ttcacagatg gcaaaacaat 11161 gacagtacct aaaggtcaag atggtcaatc agttggcgta aaaacaatta ccacagcaac 11221 aaatggagat acagttgtaa ccttcacaga cggtaaaaca atgacgatac caaaaggtgc 11281 gaaaggtgat aaaggtgacg taggtgcacg aggtgccgat ggtcgctcaa tcacaatcac 11341 aagtaataca gaagaaccaa acggtgaccg taagcttgtg ttctcagata atacaactgt 11401 catcattcca aaaggtgcga aaggtgataa aggtgatgta ggtgcaaaag gtgccgatgg 11461 tcattcaatc acaatcacta gtaatacagt agaaccaaat ggaaatcgta aacttgtctt 11521 ctcagataac acaacagttg tgataccaaa aggtgaaaaa ggtgaccgag gcgacaatgg 11581 tcatgatggc caaaacggac gtgatggtgc gtcaatcaca attactcgca cagaaacaga 11641 tgctgcaggt aacacagtta tccatttcag tgatggtaaa aatgtaaccg taccaaaagg 11701 ccaaaatgga acatcagtga caatacaaaa tatcgctaaa caaccaaatg gtgatacatt 11761 agtaaccttc tcagatggca aatctattac ggtaccaaaa ggagacaaag gtgacgcagg 11821 tgttaaaggt gccgatggtc attcaattac aatcacaagt aatacagaag aaccaaatgg 11881 tgatcgtaaa cttgtgttct cagataacac aacagttgtg ataccaaaag gtgcgaaagg 11941 tgacaaaggt gaaaatggta catctattgg catttcaaga acagaagtag atggatcagg 12001 taacacagtt gttcatttta cagatggcaa agtaatcaca ataccaaaag gtcaaaatgg 12061 cacatcagta ggtattgcaa caattacaac gtcaagtact ggtgataaag ttgtaacctt 12121 tacagatggt aaaacattga caataccaaa aggcgacaaa ggtgaccgtg gagataacgg 12181 acatgatggt acatcaatta caattactcg cacagaaaca gatggaaatg gcaacacagt 12241 catccacttt agtgatggta aaaatgtaac tgtaccaaaa ggtcaaaacg gaacatcagt 12301 gacaatacaa aatgtcacta aacaaccaaa tggcgacact gttgtaacct tctcagatgg 12361 caaaactatt acaataccaa aaggcgacaa aggtgacgca ggtgttaaag gtgccgatgg 12421 tcattcaatt acaatcacaa gtaatacaga agaacctaac ggcgaccgta aactagtatt 12481 ctcagataac acaacagttg tgataccaaa aggtgcgaaa ggtgataaag gcgacaatgg 12541 ccaaaatggt gcatcaatca caattacccg cacagaaaca gatgctgcag gtaacacagt 12601 tatccacttc agtgatggta aaaatgtaac cgtgccaaaa ggccaagacg gcacatcaat 12661 tggtattaaa tcaattacta catcaactac tggtgaaaaa gttgtaacct tcacggatgg 12721 tcaagtatta acaataccaa aaggtgaaaa aggcgaccga ggcgaaaatg gacatgatgg 12781 tcaaaacgga cgcgatggtg tatcaattac aattacaagt actacaacag atggtgcggg 12841 caatacagtc atccacttta gtgatggtaa aaatgtaact gtaccaaaag gtcaaaacgg 12901 tacatcagta acaatacaaa atgtcactaa acaaccaaat ggtgaaactg ttgtaacatt 12961 ctcagacgga aaatctatta cgatacctaa aggagaaaaa ggtgacgcag gtgttaaagg 13021 tgccgatggt cattcaatta caatcacaag taatacagaa gaaccaaatg gcgatcgcaa 13081 acttgtattc tcagataaca caacagttgt gataccaaaa ggtacaaaag gcgacaaagg 13141 tgaaaatggc acatcaatta gtattactac aattgataca gataatgatg gaaataaagt 13201 cgttcacttt agtgatggca aaacattaac tgtaccaaaa ggccaagacg gcacatcaat 13261 tggtattaaa acaattacaa cgtcaactac tggtgataaa gttgtaacct ttacagacgg 13321 aaaatcaatt acaataccaa aaggtgatcg aggcgaaaat ggtcaaaaag gtcaagacgg 13381 tcaatctatt acgattacaa gtacaacaac agatggcgct ggcaacacag ttatccactt 13441 tagtgatggt cgtaatgtta ctgtaccaaa aggtcaagac ggtcaaaatg gtacatcaat 13501 tacagtaact aatactgaat tagataaaga cggaaacgca gttgttcact ttagtgatgg 13561 caaaacagta acaataccga aaggcgcgaa aggtgatcga ggtgaaaatg gtcacgatgg 13621 ccaaaatggc acatcaatta gtattacaag tacgacaaca gatagtgcag gtaatacagt 13681 gattcacttc agcgatggta aaactgttac aattcctaaa ggtcaagacg gacatgccat 13741 cgatattcaa agtgttacta aaaacccaca aggtgataca gtaatcacat ttacaaatgg 13801 taaaacagta acaataccaa aaggcgaaaa aggtgaccga ggcgaaaatg gtcacgatgg 13861 tcaaaatggt acatcaatta gtatcacaag tacaacaaca gatagtgcgg gtaatacagt 13921 aattcacttt agtgatggta aaactgttac aattcctaaa ggtcaagacg gtacatcagt 13981 tggtattcaa aacattacaa aacaacctac tggagaaaca gttgtaacat ttacagatgg 14041 aaaatcaatt acaataccaa aaggtgacaa aggccaagat ggcaaatcta taactattat 14101 tagtaataca attgaaccaa atggtgaccg taaagttgtc ttctcagata acacttcaat 14161 tattgtgcca aaaggtgata aaggtgatca tggtgaaaat ggacatgatg gaacgtcagt 14221 aacagtaact aatacaacaa cagatggaga cggtaataca gttatccact tcagtgacgg 14281 taaaacagta accgtgccaa aaggtgcgaa aggtgataaa ggccaagacg gtacatcagt 14341 aacagtaacc gacacaacaa cagatggagc tggcaacaca gttatccact tcagtgacgg 14401 taaaacagtg actgtgccaa aaggtcacga tggccaaaat ggacatgatg gtacatcagt 14461 gacagtaacg aacacaacaa cagatggaga cggtaataca gttatccact ttagtgacgg 14521 taaaacagta accgtaccga aaggcgcgaa aggtgataaa ggccaagacg gtacatcagt 14581 cacaataaca agaactgaaa cagaccaagc tggtaataca gtagttcact ttagcgatgg 14641 tcattcaatc actgtaccaa aaggccaaga cggtcaaaat ggcacatcaa taacggtaac 14701 aaataccgaa ttagataaag acggcaatac agttatccac tttagtgacg gtaaaacagt 14761 aaccgtaccg aaaggcgcga aaggtgataa aggccaagac ggcacatcaa tcacaatcac 14821 aagaactgaa acagatcaag ctggtaatac agtagttcac tttagtgatg gtcattcaat 14881 cactgtacca aaaggccaag acggacattc aataggtatt caagaaatca ctaaaaatgc 14941 tcaaggtgaa acagttgtaa catttactga taaccactca atcactattc caaaaggtga 15001 gaaaggtgat aaaggtcaag atggtacatc agtaacagta acgaacacaa caacagatgg 15061 tgctggtaac acagttatcc actttagtga cggtaaaaca gtaaccgtac cgaaaggcgc 15121 gaaaggtgat aaaggtcaag acggcacatc aattaccgta acgaacacaa caacagatag 15181 tgctggcaat acagttatcc acttcagcga cggtaaaaca gtaaccgtac caaaaggtcg 15241 cgatggacaa aatggacgag atggtcatga tggcgtatca attaccgtaa cgaacacaac 15301 aacagatggc gctggtaaca cagttatcca cttcagtgat ggcaaaacaa ttacagttcc 15361 taaaggtcaa gatggacact cagttagcat tcaagaaata acaaaagatg ctcaaggtgg 15421 aacaattgtt aaattcacag atggacattc aatcacaata ccaaaaggtg ataaaggtga 15481 tcgtggtgaa aaaggtcagg atggtcaatc aattacaatt gtgagtcaaa gagtaactaa 15541 agaaggcaat acaattgttg aatttagtga tggacataca attactgtgc caagaggcca 15601 agatggacat tcagtcactg taaaagaaag tcataaagac caatcaggca atacggttgt 15661 agtctttagt gatggtaata caattacaat agaaaaaggt cgcgatggac gtgacggtca 15721 agatggcaaa tcaattacaa ttgtgagtca aagagtaact aaagaaggca atacaattgt 15781 cgaatttagt gatggaaact caatcactat acctagaggt caagatggac attcagttac 15841 agtaaaagaa agccatcaag atcaatcagg caatacggtt gtagtcttta gtgatggtaa 15901 tacaattaca atagaaaaag gccgtgatgg acgagatggt cgagatggcc gcgacggacg 15961 tgacggaaat aatggtcaaa atggttacaa tggtaataat ggctacaatg gtcaaaatgg 16021 ttataacggc caaaatggct ataacggtaa agatggtcag tctattcata ttgtaagtca 16081 aaaattaact aaagatggaa acactatcat tgaatttagt gatggacaca caattactat 16141 tcctggaggt caaaacggac attcagttac agtaaaagat attcaaaaag atcaatcagg 16201 caatacaatt attatcttta gtgatggtag aaaagtagtt attgaagcat caaaacaaat 16261 tcaaaaacaa gatgttaaac caacaccttc tgcagttaaa cattattaca ttgaccaaga 16321 taaaaatact gtgattatct tagctgatgg tcgagaagtt tgtgttccat gtatccaagg 16381 cacacgtgca acaatcaaat attattatat tgatcaagca ggtaatgtgc atattgattt 16441 caataatcat ccaagtattg taattccaag aaaaccaatt gaaatcacaa aaacacatca 16501 acacacaaac catcaataac catcaacatc aagactttaa tggaggttat aataactacc 16561 acaaccatta caaaggacaa catgacttta atggacaaca ttcacatcat ggtgttaata 16621 actttgtagg acatcaaggt aacgctggac atcaacatta cagtcattat gaaaactata 16681 ctcatagtca atatgatcac ggacaagcac atgctaacta cgctcatcaa gcagtacaac 16741 atcaagcata taaccgtcat gtatcatatc atggttatgg ctatacaatg actgaagcaa 16801 tggctcaata tagagatgtt gttacaaaac gctatgctct acctgaaact ggtgaaacaa 16861 catcattatc attagcatat ttaatgactc ttgttggtag tatcttactt cttagtgctt 16921 ttcgtcgcaa aaacgttaaa taagtaagta tcatataacc atttaaaaaa gctcttcctc 16981 tctttataga gggggagctt ttattttttt cacttatgaa agtgatttca taatctgaac 17041 atagtttcat aatgatagtc gttacttcat gatgacgtat agacactata taattagtag 17101 tgaaaaattg tgaaaggtat aggaggcatc attcatttat gattaaagcg attgctgtgg 17161 atatggatgg gacattttta gacagtcaaa aacattatga tgaagtaaga tttaatcaac 17221 aatttcagaa acttcaagat aaaaatatta agtttatagc agcaagtgga aatcaatatg 17281 caaagcttag atctattttt ggtgataaag agatgtattt tattgcagaa aatggtgctg 17341 tgatttatca aggcaacagc ttatatgatt ataagagttt tgatatacaa gactaccaat 17401 ctttggtgca atatttaatg ttagaacaag gacttcgaga gtttattata tgtggcttaa 17461 aaagtgctta tattttaaag gatacgtcac aaccttttaa agagaatgcg cacttttatt 17521 atcaccaatt ggaggaaatt gattcgttta acgtattacc agacgatgat tatgtaaaaa 17581 ttgcttttaa tatcaatcgg acaacgcatc ctacgcttga tgaagatatg gctatacgct 17641 ttaagtatat tgcaagttta gtatcgagtg ggcatgatag tattgacgta attatgccta 17701 gtatgacaaa aggggaagcg cttaaaggtt tgttaacaaa gtggcatatc aaacctagtg 17761 aactcatggc ttttggagat gctaataatg ataaagatat gctggcattg gcccattata 17821 gttatgtgat ggctaatagt aatgattctg aattatttga tatagcgcat gcagttgcgc 17881 caagcaatga tgaacaaggc gtattacagg ttatagatga tgtggtctta tcttaatcaa 17941 aaccacccgt gtgaacgggt ggtttgttct gcggctataa gcctttcata ctggccagtc 18001 ctaaaagggc actgataagt cagccaactg cactactatt ccagcaaccc taaagggtta 18061 ctattttttc tttctttttt taatttcttc tcctgtaaac ggatctaggt attcttccat 18121 tgtgatttga tctgcaacga tatcctcttg taattggttt cgtatataat tttcaattac 18181 ttttttgttt ctacctacag tatctacata atatcctttg caccaaaact ttctatttcc 18241 atatctatat ttcaagttgg catgtctatc aaatatcatt aaactacttt ttccttttaa 18301 atagccaaca aatgatgata cacctatttt tggcggtata ctaactatca tgtgaatatg 18361 atctttacat gcctctgctt caattatctc tacgcctttt ctttcgcaca attgacgcaa 18421 aatcattcca atatcttttt ttatttttcc atatatcact tgtcttctgt atttaggagc 18481 aaagacgata tgatacttac aattccattt tgtatgtgct aaactgtttg tgtcggatga 18541 cattaaatag catctcctcg tgttgattat tttggttggc tgaccaatat taattctagt 18601 acgaagagat gcattttttg tgacaatggt agaacctttt ctgaaccata cgcatagcgt 18661 atggttttct ttttacaaaa aagcgctaaa caagtcatat cgcttgttta gcgctttgta 18721 tatattaaat ttaatctata ttagtttaat tgagtgtcac atttaccagt ttcaatgact 18781 gataacgcag catttaatcc accttcaaca aggtttctta ctgcctcatc agagaagaaa 18841 gcaatgtgtg gtgttactaa aatattttcg tgacgaatta attctaataa tgttggatcg 18901 tcaacatctt tacctgtcca gtcataagtg aagtaatctg cttcattttc ataagtgtca 18961 attgctgcac ctgataaagt accatcattg actgcatcaa gtaaagctgg tgtgtcgata 19021 acagcaccac gagcggcatt tactaaaata gcgccttttt tcactttgct aaacattgat 19081 ttatcgaata aatggaagct ttctttgttt gcaggtacat gtaatgaaat gatatctgca 19141 tctttaattg cttcttccac agagtcttta tattctaaga aatctaaaga gtgatttgga 19201 tatgcatcaa agcctactac tttagcaccg aagccagcat aaattttacc tgttgctgca 19261 ccgatacgtc ctgtaccaat aattgcaact gtcatatttt taaccggtgt tgacataata 19321 ggtgctgccc atttgaagtt gtgtgcttga acgcgttttt caattaatgg gaatttacgt 19381 actaattgta aagctataga tacagaatat tcagcgattg tttcaggtga ataacttggt 19441 acatttgaaa taacaatgcc gtgtttttta gctaaatcta agtcatacat atcaaaacca 19501 gcagtacgtt gtgcaatttg tttaattcca tatccttcta atttaggata aacagaatct 19561 tctagtttcc caaattgcat tgttgtaaca ccgtcaaatc cttctaattg atctacagta 19621 tcagcactta agatttcttc tgaagtaacg acttcaacat tgtgtgcttt accccaattt 19681 aaagcatctt ttttctcata atcacgcgta ccgaaaaaca taatttttgt cattgaaata 19741 atctctcctg ttcctagatg atatagttat ataaatataa gacgttatac gatatataag 19801 taagctgtaa taatattggc ttgtgttata gtgtctacaa gtctcttacc tacaatatta 19861 ttatattgtg aattatttca caaatcaata gtttgcatca cattttttgt tataaaattg 19921 taccaaagca acaatatgaa aatatttaca catattttat aattcttgct ttgtattttg 19981 ccatagtggt atgtgggttt taaataattg gataatcaca atactttttt gtactgatta 20041 tatattttat aatttaagtc acactactat ttcaggaggc tttatcatgt cacaaatgaa 20101 tgaaacaatt attaatgcat taaattttcg ccatgcgacg aaaatatttg attcatcaaa 20161 acaagttagc gataaagata tgcaaacgat tttagagtca ggacggctgt caccgagttc 20221 tcttggatta gaaccatggc gatttgttgt cattgagagt caagaactaa aggataaact 20281 taaaccttat agttggggtg cacaaaaaca acttgataca gctagtcgtt tcgttgttat 20341 tttggctcgt aaaaatgtta cggcacagtc ggactatgtt caacatatcc tcagagacat 20401 taagaaatat gatacacata ccatcccagc agttgaacaa aagttcaatg atttccaaac 20461 aaattttcat ataaatgata gcgaacgtac tttgttggat tgggctagca aacaaacata 20521 tatagcctta gcaaacatga tgacttcagc agcattactc ggaattgatt catgtccaat 20581 ggaaggtttc gatttggata aagtgacgga aatattacaa gatgagggcg ttattgatac 20641 agtgcatttt gcaccttcag ttatggtggc ctttggttat agaaaagatg agccaaaagg 20701 aaaagtacgt cagccagcaa cagatgtcat tgaatgggtt aaataagtaa tgatgtaata 20761 gcattttaaa tgattaagta agggagcggg acagcattca taatgaattc gtagtcccgc 20821 cccagcaagg ttgactagga ttgaaaaaag cttagtataa gcgtattttc tatctagtca 20881 actactgcca atacatatat atatcatagc ctaaaacaaa atgatgcccc agactgtttt 20941 gtattatatg tgttttcgac ggcgcataaa gagtgctgag ccaagtactg cgagtattga 21001 agctaatgcc atactatgtt cgggcgtttc ttctttacct gtatttggta atgctttatg 21061 agtaatcggt gctgtgacag tcatatttga tgaagtagcg tgagtaactg tcggcttttt 21121 agtttgattg attaatgttt gatgagtgtg atttaattca ttatgttgtg aaggattaaa 21181 aggttgttcc acattcactg ctgctgtcga tggattaact attttactat gtttctcgac 21241 gttttgtttt tgactttgat gttgaacagc ttgtttagtt aaacgagatt ggcttgttct 21301 ttgttgactt acagttttaa cactactgcc agtatgttga atttttttag atgtagattg 21361 tttttcggtt ttaatattgt gactagagtg attattttga cttgtgtgat gcgtttcact 21421 attgataatc gttatgtcat tgatgagcca ttcaccatct gtagagccta aaataatttc 21481 agttttgctg tgtgaactac tattttgatt tgaattattt ttttctataa tgtctgttgt 21541 tttaccatat ggacttgtaa tatcgacttc tgatgtatgt ttaccagatg tgtgttgatt 21601 ttgagtattt gcctgatgct gagcctgact ttgattttgt tctgtagctg tacgactagt 21661 ttctgaagca tacgcatctt gattcgctcc taaaaatact actgttgcta gggcaactga 21721 tcctattcct attgcaaatt tacgaattcc aaaacgctgt tgttgataaa atttcacatg 21781 atcactcctt aatatgattt aataatgcct tacatgtttg ctactacttt ctagttggaa 21841 taaatgtaag gacgccacta tataaatatt ttatataatt ataaccattt taccataaga 21901 cagtgaaata aaatatagta tagttagcag tttaatagct ttttaaattt ataagcataa 21961 ttaaaatata aggtattaat gtaaagttag catatcatca tgttttaagt acggctaaat 22021 tggtaatacg ttataagcaa gttgttttta ttttttacgc agaaaaggta aaatactaaa 22081 tacgtagaaa acgctttcat tattttctac aggctttacc gcatcgaacg tattgcacat 22141 ggccttttat aaattctaag taaag //