LOCUS NC_017096:1 18833 bp DNA linear BCT 08-SEP-2013 DEFINITION Caldisericum exile AZM16c01, complete genome. ACCESSION NC_017096 SOURCE Caldisericum exile AZM16c01, complete genome. COMMENT locus start: 260333; locus end: 279165 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.546367; n0_4mer:D = 17.812196; n0_4mer:PS = 23.888415 FEATURES Location/Qualifiers source 1..18833 /organism="Caldisericum exile AZM16c01, complete genome." gene 1..771 /gene="" /locus_tag="" /db_xref="260333..261103" CDS 1..771 /gene="" /product="putative CRISPR-associated protein" /translation="MRIKLTFEDIKGREIILPIHYGYLLHYLVYNTFSEGMAQKLYLE GFPIDGKKFKLFTYSNIIEKGTKFNNTLNFGKYITFYFSSPLYEIVEDLGSNAFRKTG IVLNDFNLFLSAVEVIKPPRLTDDILIRTLSPITAYSTFNNNGKRTTHYYRPTESEFK RLIEENAQNKYILIKKAQGLPIEKDVVNDLRLDIEPYKFSIEKNKKVVYFKNTIVECF SGIYRLKGSPELIYTTYDAGLGAKSSEGFGMWDVWEKG" gene 967..1785 /gene="" /locus_tag="" /db_xref="261299..262117" CDS 967..1785 /gene="" /product="putative CRISPR-associated protein" /translation="LRAKVIFDVEGEKMPILYRHRFMDLIISALAESNRDYKLFLYPE DKTDRKIVKPFTFSVMLPQNYYLKKEKFKIFDFEVEDIVFYLSNDKRISLFISSCSYE FFVNLYNGLLSLKEFKFSSDLTLKLSKVYMLNERKINSKEVVLKTMSPILIETANDKP IIPFDESGDLLKEESLSVFNEEFNALHNRILKDIRGFQLYEKLFFSPVKIRKQVVKHA LRDFTKQTGKPYMILTTFEGIFKLRGDPKDLLMLYQLGIGLRTGQGFGMVEVIT" gene 1782..3437 /gene="" /locus_tag="" /db_xref="262114..263769" CDS 1782..3437 /gene="" /product="putative CRISPR-associated protein" /translation="MSEKFKVYLSDWLFNAGIIGFLKIMTNDNIEDQKIVTIGENYIE FERESIKGFSEKYFNTAFKQYGRYDRTLQTLKEFLEDLRNVRDSKNLETISRKYEVDK NNLGLELPLYLFNRFKNKFPYFKFLNNVLPDDEEIKKDPNKVEKIFEEVAALEEKHKE IYQKILENDVRSYLKNIYGQKSFLNNSIRTGIFNKFYNDFEKPIVENTVKQESELYCV NCGRPAKKDTSFDTGISPFFGINKDASNFLWKFNTKLPLCEICELIYFCSFAALTPSV YTKDKTFYFVNSDSSVIDLYQKNRLLSLVLKKEGNPILDFFPELIIELQKEKAYFSLR NIALIELNLNDGNFPKIYSFNISKAKALYLNENANTLKKLAKASYKIKDKERYVLFET IEKILRNEINYEFLYSLERMFLSNSNKNKQNLNPYHLQVLNLLILNFIKNTKNEGRNK MDLEEKEVWNIYFKGKELSKKMRDRNAENKIHTIAYKLLNALKASDVNYFMDVIMRTF MAYEMEIPSDMVKVLLKKDNFYPLGYGFLNGFLDKKGDEKENE" gene 3430..4347 /gene="" /locus_tag="" /db_xref="263762..264679" CDS 3430..4347 /gene="" /product="putative CRISPR-associated protein" /translation="MSKGLTYTAIFEAMSLNYGEGTGNISELKKITKGGETYTYVSRQ AIRYDIYRLLRENFFVDDKEVPLTKEQQVVQFKPDANIKDYVEMDLFGYMKTAKGQKS GSRPAVVRISPAISLEPTLGDIEFGTNKNFADRVGADPNPFQFENHYSLYTYTITIDL DKVGKDENDNIDLSTSEKADRVKMLLEVLKVLNRNIKGRIENLNPVFAIGGVYNIKNP FFLNRIKVKYDRNSGKYALDTEIINSVLDLNFGNEPVRDKTYVGYLKGYWANEEEFNK LVNNPTNIGLFFENLENEVFKNYGVEFKK" gene 4344..5063 /gene="" /locus_tag="" /db_xref="264676..265395" CDS 4344..5063 /gene="" /product="putative CRISPR-associated protein" /translation="MKVLKIKAYQPFACYRKPMNYNLWDTYPLPPLSTIKGWFHSVIK AKEYIPLSISIQGTYAAIVYDMQTLLKFDRIRRDEKQIIMDWIGKALISSPTFIATLL DVDLIIYIYSESKESLDAFRDNILKEDFPSIGRHEDLARIDFVDFVDLEEAKFDVRNA HDLTYGIYLSKETALKYGLGGINYRMNTKYVIKSNLRYFEKVDVVYVDNGRIDKGNFL FDKEDNRIVELINLESKNDNC" gene 5050..7296 /gene="" /locus_tag="" /db_xref="265382..267628" CDS 5050..7296 /gene="" /product="putative CRISPR-associated protein" /translation="MTIAKVFFKENGQFEIETLEQHTDNLLKNYENFKTKYEGDLSRL ELGKNFLELLRIACIFHDLGKVSSAFQNKVKRLLKKNEEFHKDQSEEIPHNFLSVAFL PDQNLLNLSADEEYYKLFYAIAFHHDRKINFTEQDLKKVINEDLSKKIEELSWIKKYG LSISENLWDNYYKLLDLNSSNIFNRIRRDREFILLKGLLHRLDHSSSAHLPVETEKIE EPRSKLVSYIKDNGSTLKDFQKEAEKYSDKNVILTASTGIGKTEFALNWIGEQKAFYT LPVRVSVNAMYERFAEIFGPEKVGLLHSDSLFYNLDFFSNKYDIWEEDSGIEEGIHRT LLSRQLSLPITVTTADQMFTSVFKWRGYEKIYGTLMYSKVIIDEPQSYSPQILAMIIK SLEEISDLGGKFCIISATNHPFVLDQLMRINNKPEIIGPVLDNGERHKLKIEDSEIED LTLTIKKYYDEGKKIIVLVNTVNKAQEVFKKFKEIGNVKMLHSQFIQRDRRNKEKEIM KDQKESGPVIWITTQIIEASLNIDYDVLFTEISSLDSLIQRMGRIYRGRGRYISKSDF PNVFISSVDPSDNFKIYDKEIVSFTKDVLSKYDAKIITEDIKIEMMKNVYDTKRIEGT KYYKKFKEAFALLESGFESQTKDEAQKLFRDIANLLVIPENVYIENKEKIEDALSVIN DKNQNLAKRVEAIKSFNEFTVSVPLYKVNRSQIEKKDKVYVVKAHYDQNMGLFFSNHD DDLFSNII" gene 7296..7805 /gene="" /locus_tag="" /db_xref="267628..268137" CDS 7296..7805 /gene="" /product="putative CRISPR-associated protein" /translation="MKDKNFDELKITGLRINYLHVCKRKLWLFDRGIRMEHTSNMVLL GSLLQDYYYQRKERKNILIDNLIQIDIIDNESIREVKYSNKLKEADEAQLLYYLYYLK RLGVSKKGILNYPKIKRREELILTEELEKEVEKDLEEAKKVLSLNKPPKVEKKTFCSK CAYFEFCWS" gene 7808..8788 /gene="" /locus_tag="" /db_xref="268140..269120" CDS 7808..8788 /gene="" /product="putative CRISPR-associated protein" /translation="MSRPYYIFSNGRLSRKENTLYVENANEEKRAIPIEDVEVLHIFS EIDLNSKVLNFLAQHNIAVHFYNYYGFYSGSFMPKESNTSGHLTVKQVEHYLDFEKRR YIAISFVEGAIHHMRRNLREYKETEDFIDVMSMELANVYEAKLISELMGCEGRARDAY YKAFNTIFNGKIEIKKRQKHPPNNPVNALISFGNSIIYSVVLTQIYLTQLNPTISYLH EPGEKRYSLSLDIAEIFKPLIADPVIFKLVNNNMLTAGDFEQDLNFCYLTEQGKKKFL KELDQKLNTTIRHRKLRRNVSYKLLIRLECYKLIKHLIGDELYRPFKAWW" gene 8791..9057 /gene="" /locus_tag="" /db_xref="269123..269389" CDS 8791..9057 /gene="" /product="putative CRISPR-associated protein" /translation="MSYMIVVYDVEEERINKARKVLKKYFLWVQNSVFEGEITEGKFE KCRIELSKVLDLKRDSIYFYRIENKFNYKKVVLGIEKEITDNFI" gene 10815..11060 /gene="" /locus_tag="" /db_xref="271147..271392" CDS 10815..11060 /gene="" /product="hypothetical protein" /translation="MSKKNLTNELKDWLLSNYTYDSSFYDRLYKDEVKDEEMNYFVTI MLQTHLMQLYNLVAILKDYGVGNAELINEIKNRLDGK" gene 11353..11808 /gene="argR" /locus_tag="argR" /db_xref="271685..272140" CDS 11353..11808 /gene="argR" /product="arginine repressor" /translation="MNKYKKEKRQALIKEILKTYEVETEEDLVLHLKKHNIDITQPTI AKDLKELGVIKVNKGNKSYYALPEEGSESILKKIEFAFENFVREIVVEDNLILVKTTP GNANSVAWLIDKYEIKGILGTVAGDDTILVVTKRGTTKDIIKQLEDFKK" gene 11825..13105 /gene="argG" /locus_tag="argG" /db_xref="272157..273437" CDS 11825..13105 /gene="argG" /product="argininosuccinate synthase" /translation="MKGKVVLAYSGGLDTSVILHYLVEKGYEVIAFVGNIGQSENFDE IKEKALKTGASKVYVEDLRKRFVVEFIFPALMGNAIYEGRYLLGTSLARPLLAQKQVE IAEKEGAEYVAHGATAKGNDQVRFELSYYALNPEIKVISPWKDEEFLSNFKGRSDLIE YAKKHGINVKATKDKPFSEDENLMHISHEAGIIEDPMYRPEEYIFSKTKSPKEAKDEE TIIEIYFKDGIPVKVVNPKENIVKEDPLDLFLYLNQVGSENGVGRVDMVENRFIGIKS RGIYETPGATILWTAHRDLEGIAMDKEVMHLRDMLTPKFSELIYNGMWFSPEMDFLFA AIKKSQEAIDGKVVLSIYKGNVMPIGRESPTSLYDKDLSSMDIEGGFTASDSKGFINI NAIRLKAHAAVLRRKNPYTWREILYGKTLEEKGN" gene 13074..14267 /gene="argH" /locus_tag="argH" /db_xref="273406..274599" CDS 13074..14267 /gene="argH" /product="putative argininosuccinate lyase" /translation="MAKLWKKKGIKENDTIIRFTVGNDYLFDRRLVKYDCLCSIAHAK MLNKIGILTDSEVNAITKTLEEIIHIDSKGKFQITPNDEDVHTKIENYLVEKLGDVGK KIHTARSRNDQVLCTLRLYYKSALKDIEKIVVEIINALKIFKRKYGKVQIPGFTHTRK AMVSSIKLWADSFIEALTDELKFGKSVYELIDKSPLGTGAGYGVPVLKIDRNYTKKIL GFKTLQYNPIYVQNSRGKFEGEILSFLTMIMYDINKLVSDIIFFSEDDLGFIKIPVEF TTGSSIMPHKKNPDVFEIARSKYSKLLSLEMRVKILPSNLISGYHRDLQETKECVFEG FDTVKETLIVLANVLSKLEVDKTKAHSLLTQELYATEEVYKLVLEGVPFREAYKIIGE KYLNE" gene 14364..14483 /gene="" /locus_tag="" /db_xref="274696..274815" CDS 14364..14483 /gene="" /product="hypothetical protein" /translation="LCDKNFWGVVSNFVTTEYNWFLFSIGEVLILIAVFLFIR" gene 14611..17688 /gene="" /locus_tag="" /db_xref="274943..278020" CDS 14611..17688 /gene="" /product="hypothetical protein" /translation="MNPTKEGKMNIFKRLISFLLVLMMFFLNFPFVSNAVAFYFSIFN DATASRWAISELTQAYNYGLTYPDIMGKFQQPITREEFCVIVVKLYTKLTNKTVVAGA TPFSDTSNPEIVKAYQLGIVNGTGGGKFSPTLSITRQEIATMIYRALSKAYPALPTIN KNDFPFRDKEKIASWALTSMMFAFQNGIMKGTSVDTIDPLSNTTREQGIILVKRTYEN FRTSINATLQILPTPAPTSESEKFRNLDFNALINAPVYDTKLTLYIANDSTKPLSIPT ASSGTKSGSLYTKADDGALIDMSGNKQRYFYADYGTLTPYAIVVQVSKAPFVGFKTNW NNPPALVYTTTISPAKKEFVIDFSKFVEAFPILIINTTPKTESAQVYYVRAVPVDKNM NCIGDPGEGLRVLYGKPSLGNQKLSQITVNGKPSLIKTSFELWTTQRDGDITCNGEFP NKLQHLSEVGFDCENPNDTARWFQFKNFPEDTTKIVLEISSKPFDVNDAVDNPAGLVY SSSYIPPIPAVACTGTGNSVSVKFHNFASASSTLKPGDSISYYVRAVAYSKSALAGSL DYALSDVIKVNYYKQKDITFFIPKTINVPTYIPSVKIIHYEPVQWQDPNWAHYYVVYR NPHWNEVNFEVTNGVDTLHPYMYYFENDPSMTPDRYEKEILSKWLAVGDGIQVWDRPK DESFWGQLWDGIVSFFKSLINVIAQLTNWVSQAYANLKSGLINFVVSSLPGIPDGWRD SLKKALTALVDYGLASLGIPPELPNFDALEKDGLDYLAKETLTEAGVPATDMTVDLVE KTAKGIGDNLAASANSATPNPLNCSFLKVNPMYLYRPAYMDIKITNNYDKPSQPGKLN IDVQWEWHEWNSDGGSITLSSPLSTFANGCPDAALQEGVDYRNHFLNGLKNGYPYFPV YYPIFEPVRGISIPALKPHESTTVRIYFKEYVGKNYPFAPNGATVNWDDFANLYGMVG NVGPSQFKVYTNGFTLPNLPKTYCDEKTHTIYTYVYDATTTSDSFIGVPKNAH" gene 17779..18240 /gene="" /locus_tag="" /db_xref="278111..278572" CDS 17779..18240 /gene="" /product="hypothetical protein" /translation="MTRPRFRRRIGWLPRVDYFTPVLDKGSQVESVVLTLDEVEAIRL ADLEGLYQEEAAKRMNISRQTFGRIIDSAHKKIADAIVNGKAIRIAGGPVEFVENLRE FVEGDYCVCPNCGFVKIHERGVPCRFEICPNCGSHLIREFEIKSNKRKRGE" gene 18242..18502 /gene="" /locus_tag="" /db_xref="278574..278834" CDS 18242..18502 /gene="" /product="hypothetical protein" /translation="MPLGDRTGPLGLGPRTRRGLGYCVGYGFRYGFGRGFGWGGRFVP YYGYPFGYSPSDEKAILTEELKALENELNAIKSRLAELEKEG" gene 18552..18833 /gene="" /locus_tag="" /db_xref="278884..279165" CDS 18552..18833 /gene="" /product="hypothetical protein" /translation="MIIAITSSGNTLDSMVDPRFGRCPYFIIGDPMQFKAIDNSGAGR QGGAGVNTAQFLIDEGVQILVSGNAGPNAEQALKSSVIRIITGVSGVVR" ORIGIN 1 atgagaataa agttaacctt cgaggacatt aagggtcgtg aaattatcct tcccattcat 61 tacgggtatc tcttgcatta ccttgtctac aatacttttt cagaaggtat ggcacagaag 121 ttataccttg aaggcttccc aatcgacggc aaaaagttca aactctttac ctattcaaat 181 atcatcgaaa aaggcacaaa gttcaacaac actttaaatt ttggtaaata tatcacattc 241 tacttttcat ctcctcttta tgaaatcgtt gaagatcttg gctcaaatgc ctttagaaaa 301 acaggaattg tcctaaatga ctttaacctt tttttatcag cagttgaagt gataaaaccc 361 ccacgattga cagacgacat acttatccgc acactatcac ccatcactgc ctatagcacc 421 ttcaacaaca atggcaaacg cacaacgcac tactatcgcc caactgaaag cgaattcaaa 481 cggctcattg aagagaatgc acaaaacaaa tacattttga ttaaaaaagc gcaaggctta 541 cctattgaga aagatgtcgt taatgatctt cgccttgata ttgagcctta caaattttcc 601 atcgaaaaga acaaaaaagt agtttatttt aaaaatacaa ttgttgaatg cttctcaggt 661 atctacagat tgaaaggctc tcccgaactt atctacacaa cctatgatgc agggcttggt 721 gccaagtcct ccgaaggctt cggcatgtgg gacgtgtggg agaaagggtg aaaatttagt 781 ggaaggataa gatttaagaa aggaggaaac taatggttga aacgattgca aaaattggaa 841 agatgaccag gaaattgaat ggaagatttt ttagcaaaat gaaatattgt aaaatattac 901 aaatagactg tataacttta tattttaaaa atgcttaaat atttgcagaa agaagggagg 961 aacgatttga gagcgaaagt aatttttgat gtcgaaggag aaaagatgcc tatactttat 1021 aggcacaggt ttatggacct aataatttcc gcattagctg agtctaatag agattacaaa 1081 ttgtttcttt accctgaaga taaaacagat cgaaaaatag ttaagccttt tacattcagt 1141 gttatgttac ctcaaaatta ttatctaaaa aaagagaagt tcaaaatttt cgactttgaa 1201 gttgaagata tcgttttcta tctttcgaat gataagagaa tttcactttt tataagttct 1261 tgtagttacg aattttttgt gaatctatat aatggcttat taagtttaaa agaattcaag 1321 tttagtagtg atctgacttt gaaactctcc aaagtttata tgttgaacga gaggaaaatc 1381 aactctaaag aagttgtgct taaaactatg tctccaattc ttatagaaac agccaatgat 1441 aaacctataa taccatttga tgaaagtggc gatttactaa aagaagaatc gctctcggtt 1501 tttaacgagg aatttaatgc tttacacaat agaattctaa aagatattcg cggttttcag 1561 ttatacgaaa aattattctt cagtcctgtg aagattagaa aacaggtcgt aaaacatgca 1621 ttaagagatt ttacgaaaca aactggtaag ccgtatatga tacttactac ttttgagggt 1681 atttttaaac tcagaggaga ccctaaagat ttattgatgc tttatcaatt aggtattggc 1741 ttaagaactg ggcaaggttt tgggatggta gaggtgataa catgagcgag aaatttaagg 1801 tttatctttc tgattggctg ttcaatgctg gaataattgg ttttctcaaa ataatgacca 1861 acgataatat tgaggatcaa aaaattgtta ctattggaga gaattatatt gagttcgaaa 1921 gagaatctat taaaggtttc tcagagaagt atttcaatac cgctttcaaa caatatggta 1981 gatacgatag aactttacaa actttaaagg aatttttaga ggatcttaga aatgtaagag 2041 attccaagaa cttggaaact atttctagaa agtatgaggt tgataaaaac aatttaggtt 2101 tagaactacc tttgtattta tttaaccgtt ttaaaaataa atttccctat tttaagttct 2161 taaacaatgt tcttcctgat gatgaagaga ttaaaaaaga tccaaataaa gttgaaaaaa 2221 tctttgaaga agttgcagct ttggaagaaa aacataagga aatttatcaa aaaatcctcg 2281 aaaatgacgt tcgatcgtac cttaaaaata tatatggaca aaagagcttt cttaataatt 2341 caataaggac aggtattttt aataaattct ataatgattt cgaaaaacca attgttgaaa 2401 atactgtaaa acaagaaagc gaactttact gtgtaaattg cgggcgtcct gctaagaagg 2461 atacttcttt cgacacaggt atctccccct tttttgggat taataaagat gcaagcaatt 2521 tcttatggaa atttaatacc aaactaccat tatgtgagat atgtgaactc atctattttt 2581 gtagttttgc tgcacttacg ccttccgtat acacaaaaga taagactttt tatttcgtta 2641 acagcgattc gagtgtaatc gatttgtacc agaaaaacag acttttgtct ttagtcctta 2701 agaaagaagg gaatcctatt ttagattttt ttccagaact aattattgaa ctacagaaag 2761 aaaaggcata tttttcatta agaaacatag ctttaattga gttaaacctt aatgatggca 2821 attttccaaa aatatactct tttaacattt ccaaagccaa ggcattatac ctgaatgaaa 2881 atgcaaatac tctgaaaaaa cttgcaaaag cctcttataa gataaaagat aaggaaagat 2941 atgttttatt cgaaacaata gagaaaattc ttagaaacga aatcaactac gaattccttt 3001 acagccttga gcggatgttt ttaagtaatt ctaacaaaaa caaacaaaat ctcaatccat 3061 atcatttaca ggttttgaat ttattgattt taaattttat aaaaaatacc aaaaacgaag 3121 ggaggaataa aatggattta gaagaaaaag aagtatggaa tatttatttc aaaggaaaag 3181 aactttctaa aaaaatgaga gatagaaacg cagagaacaa aatccataca attgcataca 3241 agctgcttaa tgcacttaaa gcaagtgatg taaattattt tatggatgtt attatgagaa 3301 cttttatggc atacgaaatg gaaataccat ctgatatggt aaaagtactt ttaaagaagg 3361 ataactttta tcctttgggt tatggatttt taaacggctt tttagacaag aaaggagatg 3421 aaaaagaaaa tgagtaaggg attgacttac acggcaattt ttgaagcgat gagcttgaac 3481 tatggagaag gcacaggtaa tatttctgag ttaaaaaaaa ttactaaagg tggggaaaca 3541 tatacttacg tttcacgaca agctataagg tatgatattt accgtttgtt aagagagaac 3601 ttttttgttg atgataagga ggttcctctt actaaggagc agcaggttgt ccaattcaag 3661 cctgatgcta acatcaaaga ttatgttgaa atggacttgt tcggatacat gaaaacagct 3721 aaggggcaga agtcgggttc acgtcccgca gttgttcgaa taagtcctgc tatctctctc 3781 gaacccacat tgggcgacat tgagtttgga actaacaaga attttgcaga tcgagtagga 3841 gcagatccca atcctttcca atttgaaaat cattattctc tttataccta tacaattacg 3901 attgatttag acaaagttgg caaagatgaa aacgataaca tcgatctttc gacaagcgaa 3961 aaagctgacc gtgtaaaaat gctacttgaa gtacttaaag tgttgaacag aaatatcaaa 4021 ggtagaattg aaaacctaaa ccccgttttt gcaataggtg gagtttataa tattaaaaat 4081 ccattctttt taaaccggat aaaggttaaa tatgacagga atagtggaaa gtacgctctt 4141 gacactgaaa taataaattc agtgcttgac ttaaactttg gcaatgagcc tgtacgggat 4201 aaaacatacg ttggttactt aaaaggatac tgggccaatg aagaggaatt taataaattg 4261 gtcaacaacc caaccaatat tggtttattt tttgaaaatc ttgagaatga agtttttaaa 4321 aattatggag tagaatttaa gaaatgaaag tgttaaagat taaagcatat caaccttttg 4381 cctgttacag aaaaccaatg aattataatt tatgggacac ctatccacta ccaccattat 4441 ctacgattaa aggatggttt catagtgtta taaaggccaa agaatatatc cccttgtcaa 4501 ttagtattca aggaacttat gctgctatag tttacgatat gcagaccttg cttaagtttg 4561 atcggataag aagagacgag aaacaaataa taatggattg gataggaaaa gcgctcatct 4621 catccccaac atttattgca accctattgg acgttgatct tattatttat atttattctg 4681 aaagcaagga atcattagat gcgttcagag ataacatttt aaaagaagat tttccgagca 4741 ttggaagaca tgaagattta gcaagaattg attttgtcga ttttgtcgat ttagaggaag 4801 ccaagtttga tgtgagaaat gcccatgact tgacatacgg tatatattta agtaaagaaa 4861 cggcacttaa atatggactt ggtggaatta attatagaat gaacaccaag tatgtaatta 4921 aatccaattt aagatatttt gaaaaggtag acgtggttta tgtagataat ggtagaattg 4981 ataaaggaaa ttttcttttt gacaaagagg ataacagaat tgtggagctt ataaatttgg 5041 aaagcaaaaa tgacaattgc taaagtattt tttaaagaaa atggacaatt cgaaattgag 5101 actttagagc aacataccga taatttatta aaaaactacg aaaattttaa gacgaaatac 5161 gaaggtgatt tgtcgagatt agaattaggg aaaaatttct tggaattatt gagaatagcc 5221 tgtatttttc acgacctcgg aaaagtttct tctgcttttc aaaacaaagt aaaaagactt 5281 ttaaagaaaa atgaagaatt tcataaagat caaagcgaag agatacctca taattttctc 5341 tctgttgcgt ttctgccaga tcaaaacttg cttaatttga gtgcagacga agaatactat 5401 aagttatttt atgcaattgc atttcatcat gacaggaaaa ttaattttac tgaacaagat 5461 ctaaaaaaag ttattaatga agatctctca aaaaaaatcg aagaactttc ctggattaaa 5521 aagtatggtc taagtatatc agaaaatttg tgggacaatt actataagct tcttgatctt 5581 aattcatcaa atatatttaa tagaataagg agagatagag aatttatttt attgaaaggt 5641 ttattacata gattagacca ctcatcatca gcacatttac ctgtcgaaac agagaaaatt 5701 gaagagccaa gaagcaaact tgttagctat attaaagata acggtagtac gctaaaagat 5761 tttcagaaag aagcggaaaa gtattctgat aaaaacgtaa tacttactgc ctcaaccggg 5821 atagggaaaa ctgaatttgc attgaactgg ataggtgaac aaaaggcgtt ttatacgctt 5881 cctgtaaggg tgtccgtgaa tgcgatgtat gaaagatttg ctgaaatttt cggtccagaa 5941 aaagtaggtc ttctccatag cgatagttta ttctataact tggatttttt ctcaaacaag 6001 tatgatatct gggaagaaga ctcaggaatt gaagaaggta tacacaggac acttctctca 6061 agacaactat ctttaccaat taccgtgaca acagcggatc agatgtttac ttcggtcttt 6121 aagtggagag gttacgaaaa aatttatgga actctaatgt attcaaaagt tatcatagat 6181 gagccacaaa gttattcgcc tcagatactc gcgatgataa ttaagtcttt ggaagagatc 6241 tcagatcttg gaggtaagtt ttgcattata agtgcaacaa atcatccttt tgtgttggac 6301 caattaatga ggataaataa caaacctgaa ataattggac ctgttttaga taatggagaa 6361 agacataagc taaagataga ggattcagaa attgaagatt taaccttgac aataaagaaa 6421 tattatgacg agggcaaaaa aattattgtg cttgtaaata ctgtaaataa agcacaggaa 6481 gtttttaaga aattcaagga aataggaaat gtgaaaatgc ttcattcgca gtttatccag 6541 cgtgacagaa gaaataaaga aaaggaaata atgaaggatc aaaaagaaag cgggcctgtt 6601 atttggataa caacccaaat tatcgaagca tcactgaata ttgattacga cgtattgttt 6661 acagagattt cttcgttaga ctctttgatt caaagaatgg gaagaatata caggggcaga 6721 ggtagatata taagcaaatc tgattttccc aatgttttca ttagtagtgt cgatccatcg 6781 gacaatttta agatatatga taaggaaatt gttagtttca ctaaagatgt tttatcaaaa 6841 tatgatgcta aaataataac agaagacata aaaattgaaa tgatgaaaaa cgtttatgat 6901 acgaagagga ttgaaggcac taaatattac aaaaagttta aagaagcatt tgctttgtta 6961 gaaagtggat tcgaatcgca aacaaaggat gaagcgcaaa aactatttag agatattgca 7021 aatcttcttg ttattcctga gaatgtctac atagaaaaca aagaaaaaat agaagatgca 7081 ctttctgtaa taaacgacaa gaaccaaaat ttggctaaaa gagttgaggc tataaaaagc 7141 tttaatgagt ttactgtaag tgtcccttta tacaaggtta accgatcaca aattgaaaaa 7201 aaagacaaag tatatgtagt aaaagcacac tatgaccaaa atatgggact gttttttagt 7261 aatcatgatg atgacctttt ttctaatata atttaatgaa agataaaaac tttgacgaat 7321 taaaaatcac tggattaaga attaattatc ttcatgtatg taaaaggaag ctatggctct 7381 ttgatagggg aattagaatg gagcatacat ctaatatggt cttattaggc tcattactcc 7441 aagactatta ttaccaaagg aaggaaagga aaaacattct aattgataat cttattcaaa 7501 tagatataat agacaacgag tcgatcagag aggtgaagta ttcaaataaa ctcaaggaag 7561 ccgacgaagc acagctttta tactatcttt actatcttaa gagacttggt gtttccaaga 7621 aaggtatatt gaactaccca aagattaaaa gaagagaaga acttattttg actgaagagc 7681 ttgagaaaga agtagaaaaa gatttagaag aagcaaaaaa agttttgtcg cttaataagc 7741 ctccgaaagt tgaaaaaaag acattttgct caaaatgtgc ctattttgaa ttctgctgga 7801 gttaacaatg agtagacctt attatatttt ttcaaatggt aggttgtcaa gaaaagaaaa 7861 cacactttat gttgaaaatg ctaatgaaga gaaaagggca atccccattg aggatgttga 7921 ggttctccac atttttagtg agattgattt aaatagtaaa gttctaaact ttttagcaca 7981 gcataatata gcagttcact tttataatta ttacggtttt tattcgggta gttttatgcc 8041 gaaggaaagt aatacctctg gacaccttac agtaaaacaa gttgagcact atcttgattt 8101 tgaaaagagg agatatattg caatttcatt tgttgaggga gccatacatc atatgagaag 8161 aaatttgaga gaatacaaag aaacggagga ttttatagat gtaatgagca tggaattagc 8221 aaatgtatac gaagcaaagc taataagtga acttatgggt tgtgaaggaa gagcaagaga 8281 tgcttattat aaagcattta atactatttt caatggaaaa attgaaataa agaaaagaca 8341 aaaacatccc ccaaacaatc cagttaacgc attaatttca tttggtaact ctattatata 8401 ttctgttgta ctaacgcaaa tttaccttac tcaacttaac ccaactataa gttatcttca 8461 tgagccaggg gaaaaacgat actcgctaag tcttgatata gcagaaattt ttaagccgct 8521 tattgcagat ccagttatct ttaaacttgt aaacaataat atgttgactg ctggagattt 8581 tgaacaagac ttgaattttt gctatttaac agaacaagga aagaagaaat tcttgaagga 8641 attagatcaa aaacttaaca cgactattag gcataggaaa ttaagaagaa atgtttcata 8701 caaactttta attaggcttg aatgttataa actaattaaa cacttaatag gtgacgagct 8761 ttatcgtcct tttaaggctt ggtggtaatt atgtcttata tgattgttgt gtatgatgtg 8821 gaagaggaaa gaataaacaa agcaagaaaa gttctaaaga aatattttct gtgggttcag 8881 aattccgttt ttgaagggga aattacggaa ggtaaatttg aaaagtgtag aatagaatta 8941 tcaaaggtgc tcgatttaaa aagagattcg atttactttt atagaatcga gaataagttt 9001 aattataaga aagttgtgct tggaatagag aaggagatta ccgataattt tatataatcg 9061 catcgaaggt attttttggc ttttaactaa aagaactgta ttttatacaa gcttgttaaa 9121 gttatttatc actattaaaa aaatggatta gcgggtcgat gcaaaaatga cctccgttaa 9181 atgactttta tacaaaaatt ttacttttat gatataatta taaaaaatat gtaaacgtta 9241 atgccatcag gcttagctta ccttgaaaat tatgctattt ttaaaaaggg gttttatctg 9301 aaccatgtgg gatataaaga tatcagaacc attaaatttt atcccatagc ctgaagaagt 9361 tttatctgaa ccatgtggga tataaaggaa agatgtgttg caaggtcgtc aacaaaattg 9421 agagttttat ctgaaccatg tgggatataa agcaacaatt atttgcgggc ccagaggcga 9481 gagaaaaagt tttatctgaa ccatgtggga tataaagcaa aaagaaagat aggaggtgag 9541 aaaatggaat tagttttatc tgaaccatgt gggatataaa gtacttaaaa gattatccaa 9601 aagcatatac ggttgagttt tatctgaacc atgtgggata taaaggcaag aaatttaaaa 9661 gtagaagcaa gagatttaat agttttatct gaaccatgtg ggatataaag tcgcaaaagc 9721 tttgaaaata aataggggag ctttcagttt tatctgaacc atgtgggata taaagttgca 9781 aaaaactcgc atcacaactg caacattttg cgttttatct gaaccatgtg ggatataaag 9841 tcagtatggt gcataatata aagtgtatca aaaaaggttt tatctgaacc atgtgggata 9901 taaagttcgt aaatgcttgt gtctattttt tctgtgtaat agttttatct gaaccatgtg 9961 ggatataaag catcacttta ttcacagaag gagtaaggct tttagtttta tctgaaccat 10021 gtgggatata aagaaagaaa tagggttgtt ctgggagttt ttagacagag ttttatctga 10081 accatgtggg atataaagtt ctatctcatt gacaagatta gcattgccta ctttgtttta 10141 tctgaaccat gtgggatata aagcttgtgc agactaactt tatctgcgtt aagtctcctg 10201 ttttatctga accatgtggg atataaagaa atgcaaatcg ccaagcggta taagatacac 10261 cttagtttta tctgaaccat gtgggatata aagatagatt taacgaattt tgacagaatt 10321 cacttctggg ttttatctga accatgtggg atataaagct tgtttggaga ggagatttcg 10381 taaagttcta tttggtttta tctgaaccat gtgggatata aaggcttcag aaatacgaag 10441 aagggaaaag aatgcaccgt tttatctgaa ccatgtggga tataaagagt ctatgtatgg 10501 caaacaattg ataatctttt tccacgtttt atctgaacca tgtgggatat aaagtaagga 10561 attactgatc taaatggttt actatttact gttttatctg aaccatgtgg gatataaagt 10621 taacaagaga agagttaagc attatacttt acagagtttt atctgaacca tgtgggatat 10681 aaagacacca taatctttta gaatgctaat cagattgctt gttttatctg aaccatgtgg 10741 gatgtaaatt aatgaacttt cttctcatac aaataccgaa ggagaaattt taaaacaaaa 10801 aaggaggtat taaaatgtct aaaaaaaatt taacaaatga attgaaggat tggttgcttt 10861 caaactacac ttatgacagc agtttttatg ataggttgta taaggatgaa gttaaagatg 10921 aagagatgaa ttattttgtt acgattatgc tacaaaccca tctaatgcaa ttgtacaatc 10981 ttgttgcaat tcttaaagac tatggggttg gaaacgctga attgattaat gagattaaaa 11041 ataggttgga tggcaaatga aacttcttta aataatattt gtaaagttaa tatcttctat 11101 acattctaat caccatctat agttgctgta aaaattttta gaagagtatg ttttttttac 11161 cctacccttg agggattgaa acataattat gtagggtggt gtcaggttta ctgtttttgt 11221 tttttagcgt gcttaaaaag aattgaaacc aattttcgag aggattaaaa caatctttac 11281 aaagatttaa gggtggattt ttgttttagg tcttgacata ctttcaaaat gtattataat 11341 tatgccaata atatgaataa atataagaaa gagaaaaggc aagccttaat aaaagagatt 11401 ttaaagactt acgaggttga aacagaagaa gaccttgtgc ttcatttgaa gaagcacaac 11461 atagatatta ctcaacctac cattgcaaag gatctcaaag agcttggcgt gataaaggtg 11521 aataagggaa ataaatcata ctatgcactt ccagaagaag gctctgaaag tatccttaaa 11581 aaaatcgaat ttgcttttga aaattttgta agggaaattg tagtagaaga taatcttata 11641 cttgtgaaaa ccacacctgg aaatgcaaat agtgttgcgt ggctcattga taagtatgaa 11701 attaaaggaa ttcttggaac agttgcaggt gatgatacga tacttgtcgt gacaaaaagg 11761 ggaacaacca aagacataat aaagcaatta gaagatttta aaaaataatt agggaggttt 11821 tgtaatgaaa ggaaaagtgg tgcttgccta cagtggagga cttgatactt cggttattct 11881 ccactatctt gtggaaaagg ggtatgaggt aattgcattt gttggaaaca tcggccagag 11941 tgagaatttt gacgaaatca aggaaaaggc actgaaaaca ggcgcaagta aggtctacgt 12001 ggaagattta agaaagcgtt tcgttgttga atttatcttt cctgctctta tgggaaatgc 12061 aatctatgag ggaagatacc ttttaggcac ttcgcttgct cgtccacttc ttgcacaaaa 12121 acaagttgag attgcagaga aagaaggcgc agagtatgtt gcacacggtg caacggcaaa 12181 agggaacgat caggtaaggt ttgaactttc ttactatgct cttaatcctg aaataaaagt 12241 tatatctcct tggaaagacg aggagttttt gagcaacttc aagggaagaa gcgatttaat 12301 tgagtatgca aagaagcatg gcataaatgt aaaggcaaca aaggataaac cattttcaga 12361 agatgaaaac cttatgcata taagtcatga ggcaggaata attgaagacc caatgtatcg 12421 cccagaggag tatattttct caaaaacgaa aagcccaaaa gaggcaaaag acgaagagac 12481 aataattgaa atttacttca aagatggaat tcctgtgaag gttgtaaatc caaaggaaaa 12541 cattgtaaaa gaagatccat tagatttatt tttatattta aatcaagttg gaagtgaaaa 12601 tggagtggga agagtagata tggtagaaaa tagatttatt ggcatcaaat cgcgtggaat 12661 ttacgaaacg cctggtgcaa cgattttatg gactgcgcat agagatcttg aagggattgc 12721 aatggataaa gaagtaatgc atcttagaga tatgcttaca ccaaaatttt ctgagttaat 12781 ctataacggt atgtggtttt cacctgagat ggactttttg tttgctgcaa taaagaaaag 12841 tcaagaagca atcgatggga aggtggtgct ttccatatat aaaggaaacg ttatgccaat 12901 aggaagagaa tccccaacct ctctttatga caaagatcta tcgagtatgg atattgaagg 12961 tggttttact gcttctgatt caaaaggctt tataaatata aacgcaataa ggttaaaggc 13021 gcatgcagca gttttaagga ggaagaatcc ctacacttgg agagaaattc tatatggcaa 13081 aactctggaa gaaaaaggga attaaagaaa acgatacgat tattagattt acagttggta 13141 atgactattt gtttgataga agacttgtga aatacgattg cctttgctct attgcacatg 13201 caaagatgct caataaaatt ggaatactaa ctgatagcga ggtaaacgcc attacaaaga 13261 cacttgaaga aatcattcat attgattcaa aaggaaaatt tcaaattact cctaacgatg 13321 aagacgtgca tacaaaaatt gaaaattacc ttgttgaaaa attaggtgat gttggcaaaa 13381 agatacatac tgcgcgatca agaaatgatc aagtactctg caccttacgc ctttattaca 13441 aaagtgctct aaaagatatt gaaaaaattg ttgtggaaat tattaatgca cttaaaatat 13501 tcaaaagaaa gtatggtaag gttcaaatac cgggctttac tcacacaaga aaggcaatgg 13561 tttcatctat taaattgtgg gcagattcgt ttattgaggc acttactgat gagttaaaat 13621 ttggaaaatc agtgtatgaa cttattgata agtcgccttt gggcactggt gcaggatatg 13681 gagtacctgt gttaaaaata gacagaaatt atacaaaaaa gattcttgga tttaaaacat 13741 tgcaatataa tcccatatac gtgcaaaact ccaggggtaa atttgaaggc gaaattcttt 13801 ctttccttac aatgattatg tatgatataa acaaacttgt ttctgatatt atcttctttt 13861 cagaggatga tttaggattt ataaaaatac cagtagagtt tacaacggga agttccataa 13921 tgccacacaa gaaaaatcca gatgtttttg aaattgcacg aagtaaatat tcaaaacttc 13981 tttcccttga aatgagggta aaaattttac cgtcaaatct tatttcaggc tatcacaggg 14041 atttgcagga gacaaaagag tgtgtctttg aaggcttcga taccgtaaag gaaactctta 14101 tagtgttagc aaacgttttg tcaaagttag aagtagataa aaccaaggcg catagtcttt 14161 taacccagga actatacgca acagaggaag tctataaact cgtcttagaa ggtgttcctt 14221 ttagagaagc ctataaaata attggggaga aatatctaaa cgaataagtc aaatactttt 14281 agtaatctat aggtcttaac tattatctat gattattcga agatggtttt aagttatatt 14341 tttaagtatg gagttaacaa tttttgtgtg ataaaaattt ctggggtgtc gtctcaaatt 14401 ttgtcacaac agaatataac tggtttttgt tttcaatagg cgaagtttta attttgattg 14461 ccgtttttct ttttattcga tgaaccacta aaactaagaa ataaaaaaat tttatttgct 14521 ttaatttttg ttttgcataa aattgagtat ggctaatctt taacaacata aaatcttaat 14581 gtcattaaag aaaggtcata aagtgaggtt atgaacccca caaaggaggg aaagatgaat 14641 atctttaaaa ggcttatatc tttcttactt gttttaatga tgttcttttt gaactttccg 14701 tttgtaagta atgctgttgc attttacttc tcaattttta acgatgcaac agcaagcagg 14761 tgggcaatct cagaactcac acaggcttac aactatgggc ttacttaccc tgacattatg 14821 ggtaaatttc agcaaccaat cacaagggaa gaattctgcg ttattgttgt aaaactctac 14881 actaaactta cgaataaaac ggtagtggca ggagcaactc ctttttccga cacaagcaat 14941 cctgaaattg taaaggcgta tcaacttggt attgttaatg gaacaggcgg tggaaaattt 15001 tcaccaactc tttccataac aagacaggaa attgcaacaa tgatttatcg agcactgtca 15061 aaggcttatc ctgcgcttcc aaccattaat aagaacgact ttccatttag ggataaagaa 15121 aaaatcgctt cgtgggcact tacaagtatg atgtttgcat tccaaaatgg aattatgaag 15181 ggcacatcag ttgatacaat cgaccctctc tcaaatacaa caagagaaca agggattatt 15241 cttgtaaaaa ggacctatga aaatttcaga acttccatta atgctacact tcaaattctt 15301 ccaacacctg cacctacaag cgaatccgaa aaatttagaa atcttgattt caatgcgtta 15361 ataaatgcgc ctgtgtatga tactaaattg actctttata ttgcaaatga ctcgacaaaa 15421 cccttgagca ttccgacagc atcgtcaggt acaaaaagtg gctcgcttta cacaaaggca 15481 gacgatggtg ctctgattga tatgtcgggc aacaagcaac gctattttta tgcagattat 15541 gggactttga ctccttatgc aattgttgtt caagtttcaa aggcgccttt cgttggtttc 15601 aagacaaact ggaataatcc gccggctctt gtttatacaa caacgatatc gcctgcaaaa 15661 aaagaatttg ttattgattt ttctaaattc gttgaggcat ttccgatcct tataatcaat 15721 accacgccta aaacagaaag tgcacaggtt tattacgtaa gggctgttcc tgtagacaaa 15781 aatatgaatt gcatcggaga cccgggtgag ggattgcgag tgctttatgg aaagccaagt 15841 ttgggaaatc aaaaactctc tcaaattact gttaacggaa agccaagttt aataaaaacg 15901 tcttttgaat tatggactac ccagcgtgac ggagacatta cctgcaatgg tgagtttcca 15961 aataaactcc aacatttaag cgaagttgga tttgattgtg agaatccgaa tgataccgca 16021 agatggttcc aattcaaaaa ctttccagaa gacacaacaa aaattgtctt agagatttct 16081 tcaaagccgt ttgatgtaaa tgatgctgtc gataatccag cagggcttgt ttattcaagc 16141 tcatatatac caccaattcc tgcggtagca tgcactggaa ctggaaattc tgtttccgtg 16201 aagtttcata attttgcatc ggcatcttct acccttaaac caggcgattc tatctcgtac 16261 tatgtaaggg ctgttgcata ttcaaaatct gcattggcag gatctttgga ttatgctcta 16321 tccgatgtta taaaagtgaa ttattacaag caaaaggaca ttacattctt tataccaaaa 16381 actattaatg ttcccacgta tattccatcc gttaagataa ttcactacga acctgttcaa 16441 tggcaagacc caaactgggc acattactat gtggtgtatc gaaatccaca ttggaacgag 16501 gtaaactttg aagtaacaaa cggagtcgac actctccatc cttatatgta ctactttgaa 16561 aatgatccct ctatgactcc tgaccgctat gaaaaagaaa ttctctcaaa gtggcttgcg 16621 gtaggagacg gaatacaggt ttgggatagg cctaaagacg agtcgttctg gggacaattg 16681 tgggatggga ttgtctcatt ctttaagtct ttgataaacg ttatagctca acttacaaac 16741 tgggtatcac aggcatatgc caatttgaaa tcagggctaa ttaattttgt tgtatcgagt 16801 cttcctggaa tccccgatgg ttggcgtgac agtttgaaaa aagcgcttac tgcacttgta 16861 gattatggct tagcttctct tggaattcct ccagaacttc caaattttga tgcacttgaa 16921 aaagatgggc ttgactatct tgcaaaagaa acactaactg aagcaggtgt gcctgcaacg 16981 gatatgaccg ttgatttagt tgaaaaaact gcgaaaggta ttggtgataa tcttgctgcc 17041 tcggcaaatt ctgctactcc aaacccgctt aactgttcat tccttaaagt taatccaatg 17101 tatttataca ggcctgcata tatggatatt aaaatcacta acaactatga caagccatcg 17161 caacctggta aattgaatat agacgttcaa tgggagtggc acgaatggaa ttctgatggt 17221 ggaagtatta cactctcaag cccactttct acttttgcaa atgggtgtcc cgatgctgca 17281 cttcaagaag gagtggatta ccgtaaccac tttcttaacg gactcaaaaa tggatatccg 17341 tactttcctg tttactatcc gatatttgag cctgttaggg gcatttcaat acctgcgctt 17401 aagccacatg aaagcacgac tgttcgtatc tatttcaagg aatatgtggg aaagaattat 17461 ccgtttgcac caaatggagc aactgttaac tgggacgatt ttgcaaacct gtatggaatg 17521 gtaggaaatg ttggaccatc gcaattcaaa gtttatacaa atggtttcac actacctaat 17581 ctccctaaaa cttattgcga tgagaaaaca catacaattt atacgtatgt ctatgatgca 17641 acaactactt cagattcatt cataggagta cccaaaaacg cgcattaaat aaatacccaa 17701 aagtttttca aaagtgggtc cttttaaact cttgactatt atgagcatat gcttataata 17761 ttgtagaagg taagtgatat gacaagaccg agatttagaa gaagaattgg atggcttcct 17821 cgcgttgact actttactcc tgttttagat aagggtagcc aagttgaaag tgttgtgctt 17881 acacttgatg aggtagaggc aattcgcctt gcggatcttg agggactata ccaagaggaa 17941 gccgcaaaga gaatgaatat ttcaaggcaa acattcggaa gaattattga ttctgcacac 18001 aaaaagattg cagatgcaat tgtaaacgga aaggcaataa gaattgcagg cggcccagtt 18061 gagtttgttg aaaatcttag ggagtttgtt gagggggatt actgtgtttg cccaaattgt 18121 gggtttgtca agatacacga aagaggtgta ccttgcaggt ttgagatttg tccgaattgc 18181 ggaagtcatt tgataaggga atttgaaata aaaagcaata aaagaaaaag gggtgaatag 18241 tatgccatta ggagatagaa ctgggccact tggcttaggt ccaaggacac gaagaggact 18301 tggctattgt gtaggatatg gttttagata cggtttcggg cgaggttttg gttggggtgg 18361 aagatttgtt ccctattatg gatacccgtt tggatatagt ccttcagatg aaaaagcaat 18421 ccttactgaa gagttgaaag cacttgaaaa tgaacttaat gcaataaaat ctcgtcttgc 18481 agaattagaa aaagaaggat aggattctat gccccgggtg taagcccgga gactattttg 18541 ggaggtgaaa aatgattatt gcaataacct caagtggaaa tacgcttgac tcaatggtag 18601 acccaagatt tgggagatgc ccgtatttta ttattggcga tcctatgcag tttaaagcga 18661 ttgataatag tggcgcagga cgtcagggag gtgcaggggt gaatacagca caattcctca 18721 ttgatgaggg agttcaaatt ttggttagcg gaaatgctgg accaaacgca gaacaagctc 18781 taaaaagtag tgtcattaga attataactg gagtttcagg cgtggtaaga tga //