LOCUS NC_016931:7 19229 bp DNA linear BCT 05-SEP-2013 DEFINITION Rickettsia massiliae str. AZT80 chromosome, complete genome. ACCESSION NC_016931 SOURCE Rickettsia massiliae str. AZT80 chromosome, complete genome. COMMENT locus start: 773871; locus end: 793099 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.867237; n0_4mer:D = 13.045963; n0_4mer:PS = 23.819893 FEATURES Location/Qualifiers source 1..19229 /organism="Rickettsia massiliae str. AZT80 chromosome, complete genome." gene complement(1..1377) /gene="rho" /locus_tag="rho" /db_xref="773871..775247" CDS complement(1..1377) /gene="rho" /product="transcription termination factor Rho" /translation="MSTTNKESTAELNNTESNNNHNNFTENGNIINLKQLKRKLPEEL QAQAEELKIENINSLLKQELVFAILKKSVEQGGLIVGEGVLEVLPDGFGFLRSPEVNY LAGPDDIYISPSQIRRFGLRTGDTVEGQIRAPKAGERYFALLKVNRVNFEDPFKAYHR VHFDNLTPLYPDEKLGLELENNSKDSKDFSTRVIELVAPMGKGQRALIVAPPRTGKTV LLQNIAHAITTNNPEVFLIVLLIDERPEEVTDMQRSVRGEVVSSTFDEPASRHVQLAE MVIKKAKRLVEHKKDVVILVDAITRLARAYNTVVPSSGKVLTGGVDANALQRPKRFFG AARNIENGGSLTIIGTALIETGSRMDEVIFEEFKGTGNSEIVLDRKIADKRIYPAIDI TRSGTRKEDLLVDKIILNKMWVLRRIIDPMGSSEAIEFLLKKLENTKTNGEFFEMMKS PERPKNGL" gene complement(1748..3070) /gene="" /locus_tag="" /db_xref="775618..776940" CDS complement(1748..3070) /gene="" /product="putative methyltransferase" /translation="MSNLKKTKNTTISKDLAEVQEHYQDYPYPFRDPNQEKERLLTIC GEFLGELNHFLYQGKENFNNNFRCLIAGGGTGDSTIYLAEQLKDKNAEIIYLDFSKPS MEVAQKRAEVRGLKNIKWINDSILNIPNLKLGKFDYINCTGVLHHLANPDEGLKNLKD SLKPTGGMGLMVYAKYGRTGVYQIQDLMKMINKDTKSRVEEVMNGKLILDNLPATNWY KRGWELFSDYQNYGDVGVYDMFLHKQDRAYSVPELYEFVEKASLNFVDYFDPLEKILL RPENYIKDFSLLQKVKKMDKVTREAISEILTGNIIKHSFYVSNRKDSVASLDDLDNIP YFHNIANFAKQIYEHLESNPSAVNNAINFTINNGILNNVNISMSIFRSTKYIFKYMVE EKSLREIFDAVRSELNQEISNEALLNEVKNVCIPLLNTNVLLLKSKDC" gene complement(3113..4876) /gene="" /locus_tag="" /db_xref="776983..778746" CDS complement(3113..4876) /gene="" /product="single-stranded-DNA-specific exonuclease RecJ" /translation="MKPQASINGKIWQQKLINEDIVTELCRSFKISDLLARIVSLRVN NLEEVENFLIPKIKNLLPDPFHLLDMEKAVDRTVTAILNNQKICIFADYDVDGATSAA LLKNIFRDLNILCDIYVPDRIAEGYGPTPFAMQKIKDNGTELLITVDCGAMAHEALKY AKDVNLDVIVIDHHITTEILPDAVAIVNPNRIDEKSEYKHLAAVGVAFLFTTAILSNL KKQNYFTQTMLQPNLMKYLDLVALGTVCDMMKLTGLNRAFVASGLKIMQQRQNIGIKT LYDMAGLNEIPKCYHLGFILGPRINAGGRVGKSSLGANLLSTSCSNEAKKLAEELEKH NNERKVIELLMIEEAMEIALTQQDSSLLFIVKEGWHPGVIGIVAGKLKEKFDKPVAVI ALNDGIGKASCRSILGIDFGAEIINAKSKDLLIAGGGHAMAAGFTVTADKLQELQNFF NNAFRISINKLENYKHAEYDIELTVNSVNFPLMEELNTLEPFGQGNHEPIFKFDDLFV LKADIVGSKHIKCMLVPNKRGFGNKALSAIAFNSVGTAFEDVLLSSKAKNIAAIGTLK TNNWQGNYTIQLIIKDILLKE" gene complement(4884..5969) /gene="prfA" /locus_tag="prfA" /db_xref="778754..779839" CDS complement(4884..5969) /gene="prfA" /product="peptide chain release factor 1" /translation="MRFSDNLAKILDKYENLGNKLSSGIMGDEFVKASKEYAELEDVV AKIKEYNKAKSELEEANNFKLEVGLDNATLEMIEDEIHTLENSLPKLERAVKIALLPK DDADSKSAIIEVRAGSGGEEAALFAAVLFNMYQRYAELKGWRFEILAISDTGIGGYKE ASASIKGKDVFSKLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDIQIEDK DLRIDTYRASGAGGQHVNTTDSAVRITHIPTGITVALQDEKSQHKNKAKALKILRARI YEEERRKKEQERADSRRGQVGSGDRSERIRTYNFPQGRVSDHRINLTLYKIDEVVKNG QLDEFVEALIADDEAKKLLGIYSKNTA" gene complement(6102..7340) /gene="" /locus_tag="" /db_xref="779972..781210" CDS complement(6102..7340) /gene="" /product="branched-chain alpha-keto acid dehydrogenase subunit E2" /translation="MPIKILMPALSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKA TMEVEAVDEGILAKIVIPQNSQNVPVNSLIAVLSEEGEEKTDIDAFIAKNNSVSPSPK TDANLLKPHENLANVEEQVTVIKHDASKIFASPLAKRLAKMGNIRFESVKGSGPHGRI VKQDILSYTPSTAHNKIVSRNPEEYRLVPNNNIRKIIAKRLFESKQTVPHFYLSIECN VDKLLDIREDINKSFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNV DISVAVAIENGLVTPIVKNANQKNILELSREMKELIKKAKDNKLTPEEFQGGGFTISN LGMYGIKNFNAIINPPQSCIMGVGASAKRAIVKNDQITIATIMDVTLSADHRVVDGAV GAEFLAAFKKFIESPALMLI" gene complement(7486..7932) /gene="infC" /locus_tag="infC" /db_xref="781356..781802" CDS complement(7486..7932) /gene="infC" /product="translation initiation factor IF-3" /translation="MHGIVNIREALDMAERAGLDLVEISPNAVPPVCKILDFGKFKYE SKKRLHEARKKQKIVVLKEMKFKPNISIGDFETKLKKIKEFLKDGDKVKISLWFKGRE ILHKEVGQALFKRIEIGLAGLVKIDQHAKMEGKQMIMIVSPDIKVQ" gene complement(8110..8439) /gene="" /locus_tag="" /db_xref="781980..782309" CDS complement(8110..8439) /gene="" /product="hypothetical protein" /translation="MKETKRFFYKNNRLNKGYAKTFSVNEPDNNFYHKKFEHILPPID LISEYESIYPGTLQELMHMAQKEQAHKHAIDLKNLKIQARVTKLTRICLLIFGMCLVV SIFFKTF" gene complement(8426..8599) /gene="" /locus_tag="" /db_xref="782296..782469" CDS complement(8426..8599) /gene="" /product="hypothetical protein" /translation="MKQSFIKLIYAELKNIINMKSSKQQQKKETQLIDYFKIVESNIL YTFQKIKKEYERD" gene complement(8650..8892) /gene="" /locus_tag="" /db_xref="782520..782762" CDS complement(8650..8892) /gene="" /product="hypothetical protein" /translation="VVQIEKQDLLILRFILGKSPYKFYAYGSNRFNSKVLSNFGDLII LEDIIPDYVKDAEEVKITAGCDKNFITCCAINLIML" gene complement(8879..9208) /gene="" /locus_tag="" /db_xref="782749..783078" CDS complement(8879..9208) /gene="" /product="nucleotidyltransferase substrate binding protein" /translation="LRKHLDTEQNKACSIQSFEFCYELAWKTMKRFCEKSGKTPYILK DVFRAAAVNGLISDPRIWFKFIEIRNITVHTYNEKNLELVISIFDDFSDALNELINNL EKYSGSD" gene complement(9659..9790) /gene="" /locus_tag="" /db_xref="783529..783660" CDS complement(9659..9790) /gene="" /product="hypothetical protein" /translation="MEEDRWIEKLTSYAEIKSLCDSKFLALEKYKLRTYNNRRIFFI" gene complement(11110..11337) /gene="" /locus_tag="" /db_xref="784980..785207" CDS complement(11110..11337) /gene="" /product="hypothetical protein" /translation="MINNQDKKLTSDAMFTAARDQYITDINRLLIRSETNTLEMTPKN ENIICDLHQKIKRNILLRARGDNLLFISILL" gene complement(11359..11715) /gene="" /locus_tag="" /db_xref="785229..785585" CDS complement(11359..11715) /gene="" /product="hypothetical protein" /translation="MNAVQGEWRKIPVPEYLILSNLKSIITDFNSTLPTEYHLITDES VFECKEAINEFTVLGNNKDKHKSIIQKPQETEAIIKPTNNAQSQSITSKPIEEYREYV KNDDYGLTGATHCTIS" gene complement(11759..11962) /gene="" /locus_tag="" /db_xref="785629..785832" CDS complement(11759..11962) /gene="" /product="hypothetical protein" /translation="MLYFQGAMFLGSNDACTYLSEFYKNGNHLGINKEQLSNLIKIVI NIGKFLHHSKLTNSVCLKDFRIF" gene complement(12095..12325) /gene="" /locus_tag="" /db_xref="785965..786195" CDS complement(12095..12325) /gene="" /product="hypothetical protein" /translation="LSVNINEKFLKPSVVTHVKTIEICQQQNSEDPFAINEDEIIENF NLTLDSLRIFVTVTIDYSGLVSSITIDEDEIK" gene complement(12442..12645) /gene="" /locus_tag="" /db_xref="786312..786515" CDS complement(12442..12645) /gene="" /product="hypothetical protein" /translation="MPQGNNNPSYLPQVFLTNAYEQLNEFKKLSSNNIRTLMQDFYKI EKAFKCTLFTGNNNACEGLVELI" gene complement(12700..13512) /gene="" /locus_tag="" /db_xref="786570..787382" CDS complement(12700..13512) /gene="" /product="biotin-(acetyl-CoA carboxylase) ligase" /translation="MNIGKFKLIVFDKLDSTHSEAIRMAQNTKVDSNYAVLAKSQTNG RGRSGKNWQSRSGNLHVSLLIKPDKELELLPQLSFVTALSVYDSITSLCHSHSALCHS RESRHDIRNENNIIQLKWPNDVLINGRKIAGILLESVKVENNYYLIIGIGINITYHPD NIDQPTTSLISENLPPIEAQALLEILIENFEEYYQIWHNNGFPFIRKKWLEHAYKLYE NISVKYQNDIVTGLFKDIDNTGRIILQLPSKKIISFSTAELFFSKNITKFKL" gene complement(13621..15417) /gene="" /locus_tag="" /db_xref="787491..789287" CDS complement(13621..15417) /gene="" /product="putative esterase of the alpha/beta hydrolase superfamily protein" /translation="MADITVRKHPIINNLKQESKTPVVNEQSDILEELKDLQKIQQSS SNQTKTLQELEQAQKAPIEYIAFSGGGAKGAIYSGAYEAVKKAGILDNVKAVAGSSAG AITATVVALGTPPERFEEISKNTNLQTLLGKKGFSAGIVQLNKDGKPLYALLELVIKE NIGKFLQRSDIVNVKDDKALDELRERYNQKDGKIYFKDIALLRKYDPVQYKDLVITAT QQETSELTIFNSFDTPNVEIALACRASASIPLVFKPVEIDDKKYIDGGYRDNIPTKYF KGNEPEFDTKAVTDNMEEITLAKKQGRTLAMAFGTGMEADANIAIYSAKKFESPSDIV KFLADILFKTLAKVGGKFKYTETLRATNEQLRENALNTVVLDTAGIDTLDFKDAQKYS DYLHIKGYCQTREHLNNHDLGKEADKIFDHQKFLLNVYEVYDNKNLHKTFGTKLLEMF IPSKENNTSKWQDGVIENHNDKAKMLLSFCKTGALNEKELNEKLKEYVIIAATSRNNT LKADTNSLNALLYTLNDTAASSKIKDSFIEVLGIDKNQDVRFDKTKTFDENIAKFKFT KQDLESFITKSKSEAPKIQSKHSVATSHVSRG" gene complement(15422..16051) /gene="" /locus_tag="" /db_xref="789292..789921" CDS complement(15422..16051) /gene="" /product="superoxide dismutase" /translation="MTYCNKSNQTSYPFILPDLPYEKESFKPHFTLETFDYHHGKHHN VYVQNLNNLLKDKEELQKKDLEEIIEWSSQNSNAAIFNNAAQIWNHTFFWHSIKPQGG GKPSGKILEQINKDFGSFAEFCEQFKQEAVGQFGSGWAWLVYHDNRLQIIKTANAGTP IANGMKPLLACDVWEHAYYIDYRNKRPDYVDIFIKHMINWKFVEDNLIK" gene complement(16222..17502) /gene="" /locus_tag="" /db_xref="790092..791372" CDS complement(16222..17502) /gene="" /product="folylpolyglutamate synthase" /translation="MLMPHFPVPTWKNNIKYDLENIARLLRALGNSHLRLPPVIHIAG TNGKGSSSAMLKSIFTLAGYKVHCYTSPHLLEFNERIVVAGEKISDNELWQVCEQVRV ASEKFNIEPSFFEGTTAAAFLAFEKTKADILILETGLGGRLDATNIVERPLITLVTPI SHDHMHMLGNTLPLIAVEKAGIMKSCVPCVISMQALEVYETLFAKADELEVPSFCYEY DFGIKKTGNGFIYSSRNFTYEFPTPSLLGDHQLINAASVIALISLINKQFNINNEVIA KGLQNTIWPARIEKIEPKKYSKLIGDNVQIWIDAAHNNSGAQVLANWMRDNLKSSIYL ILGMTQNRNIEEFCSYFKGLTIKGYGVKVLSEPLSHSAETINLEGRKSGIDFSASDSL EEAISDIKKINGDNKANIIITGSLYLASDFHKLL" gene complement(17756..18298) /gene="" /locus_tag="" /db_xref="791626..792168" CDS complement(17756..18298) /gene="" /product="BioY family protein" /translation="MQLNSIALQLTTRQAIEIVLGVALLTICSQIVIPIKPILISLQT VAVIFIGLTYNKTTAPLTILSFITLGAMGIPVFGEFSSGLRILFGPTGGYLAGFVIAV YVMANLKDKIFTSNKWLNQISLCLIGNIIIMSLGWMWLSTLLGASGAFYGGVLPFIIP GIIKSVLLIGLINAVKPKTR" gene 18374..19126 /gene="" /locus_tag="" /db_xref="792244..792996" CDS 18374..19126 /gene="" /product="biotin-protein ligase" /translation="MKIKIYNDLGVSKESIKHCVYTLRLYAPKYNVDYITAQEIIDEK WVQNTLLLILLGGRDLYYVQKLQGTGNANIKNYIKNGGNFLGICAGSYYSGNYVEFAK GTNIEVISKRELKIFNGTVRGPLLAPYYYNSHKGARAAYLKINPTLNLNIKDCYAFYN GGGYFIDAENTKDTEIIASYEDSQAAIIKCTYGDGTAILSGVHLEYEPALINNQSLNN IRKILKAHDTERIKLLNSILDFFGNSLIERNL" ORIGIN 1 ctatagaccg ttcttaggac gttcaggact cttcatcatc tcaaaaaact caccgttagt 61 tttagtattt tcaagttttt tgagtaaaaa ttctattgct tcactgctac ccatcggatc 121 gataatacga cgaagaaccc acattttatt taatattatt ttatctacta ataaatcttc 181 ttttctagtg cctgatctag ttatatcaat agccggataa atacgcttat cggcaatctt 241 acgatctaga actatctcgg aattacctgt acctttaaac tcctcaaaaa ttacctcatc 301 catacgagaa ccggtttcaa ttaaagccgt accgattata gtaagcgaac cgccgttttc 361 aatatttctt gctgctccga aaaatctttt aggtctctga agagcattag catcaacacc 421 gcccgttaat actttacctg atgacggcac tacggtatta taagcacgag ctaaacgtgt 481 tatcgcatct actaaaatta ccacgtcttt tttatgttct actaaacgct ttgctttttt 541 gataaccatt tctgcaagtt gtacgtgcct acttgccggt tcatcgaaag tagagctaac 601 aacctcccca cgcacggaac gttgcatatc ggttacttct tcaggtcttt cgtctattaa 661 cagtactatt aaaaatactt ccggattatt ggttgtaatt gcatgtgcta tattttgtaa 721 taatacggtt ttacctgtac gaggcggtgc tactattaat gcacgttgtc ctttacccat 781 aggggcaaca agttcaataa cccgtgtact aaaatcctta ctatctttac tattattttc 841 aagttctaat cctaattttt catcaggata taagggggtt aaattatcaa aatgaacacg 901 atgataagct ttaaaagggt cttcaaaatt tactctattg actttcagta aagcaaaata 961 acgttctccg gcttttggag ctctgatctg accttctacc gtatcaccgg tacgcagacc 1021 aaagcgacga atctgactag gagaaatata aatatcatca gggcctgcta agtagtttac 1081 ttccggcgaa cgtaaaaaac caaatccgtc aggtagtact tcaagtaccc cctctcccac 1141 tattaaacct ccctgctcta cggatttttt caaaattgca aaaactaatt cttgtttaag 1201 taatgaatta atattttcaa tttttaattc ttctgcttga gcttgtagtt cctccggtaa 1261 tttacgtttt aattgtttta aattaataat attaccgttc tctgtaaaat tattatgatt 1321 gttattggat tcggtattgt taagttctgc tgtggattct ttattagttg tgctcattag 1381 attataattg aaaagttgag ttagcaattc agtttaaagg taagtaatat acttatttaa 1441 attaggaatc aaattagatt tttagaaagt tttatttatt cttgcggttt gaagaattat 1501 ttatcttgtt agcttataag agttgtctat gtatgtaaaa gcatactaac aacgttaata 1561 gcatattgtc aacccaaatc gtcattgcga gcaggtaatc ggtaaatggt cattgcaaga 1621 aaattacgaa gcaatcttgg gagtttatta ttatttcatg agattgccgc acagcttacg 1681 gctgcgtagc tcatgacgac cctggtaacc tcttttcgca atgacggata aatcaatcca 1741 cgtaactcta gcaatccttt gattttaaca ataacacatt tgtattaagt aatggaatgc 1801 atacgttttt aacttcattt aataaggcct cattgcttat ttcttggttt aattcgctgc 1861 gtaccgcatc aaatatttct cttaaacttt tctcttctac catatattta aaaatatatt 1921 tagtgcttct aaatatcgac attgagatat taacattatt taatatccca ttattaatag 1981 taaaattaat agcattattt actgctgaag gattagattc caaatgctca taaatttgtt 2041 tagcaaaatt ggcaatatta tggaagtacg gtatattatc aaggtcatca agagaggcta 2101 cactatcttt tcgatttgat acgtaaaatg aatgtttaat aatattaccg gtaagtattt 2161 cggaaattgc ttctctagtt actttatcca tttttttaac tttttgtaga agtgaaaaat 2221 cttttatata attttccggt cttaataaaa ttttctctaa aggatcaaaa taatcaacaa 2281 aatttaagct tgctttttct acgaattcat ataactcagg aacggaatag gctctatcct 2341 gtttgtgcag gaacatatca taaactccga cgtcaccgta attttggtaa tctgaaaata 2401 actcccaacc tcttttatac cagttagtag caggcaaatt atctagaatt agcttcccgt 2461 tcattacttc ttcgacacgg cttttagtat ctttatttat cattttcatt aaatcctgaa 2521 tttgataaac accggtacgt ccgtatttag catataccat taaacccata ccgccggtcg 2581 gctttaaaga atcttttaga ttttttaaac cttcatcagg atttgctaaa tgatgaagca 2641 cgccggtaca atttatataa tcgaattttc caagttttag attaggtata tttaatattg 2701 aatcattaat ccatttaata tttttaagac ctcgtacttc tgcacgtttt tgtgctactt 2761 ccatgctagg cttgctgaaa tctagatata ttatttcggc atttttatct tttaactgct 2821 cggcaagata aatagtcgaa tcaccggtgc cgccgcctgc tattaagcat ctaaaattat 2881 tattaaaatt ttcttttcct tgatatagaa aatggtttaa ttctcctaag aactcaccgc 2941 atattgtaag taaacgttct ttttcttgat ttgggtctct gaagggataa ggataatctt 3001 gataatgctc ttgtacttct gctaagtctt tagaaattgt agtatttttt gttttcttta 3061 aattgctcat aaattattat tttttaagtt attattatat atacttgtct atctactctt 3121 ttagaagtat atcttttata attaattgaa tagtataatt accttgccaa ttattagttt 3181 ttaacgttcc tattgcggca atattttttg ctttagagct taataaaaca tcttcaaatg 3241 cagttcctac cgaattaaaa gcaatagcag ataaggcttt attaccaaag cctcgcttat 3301 ttggaacaag catacattta atatgcttac ttccaacgat atccgctttt aatacaaata 3361 aatcatcgaa tttaaatata ggctcatgat ttccttgacc gaaaggctct aaagtgttta 3421 attcctccat taaagggaaa ttcacactat taaccgttaa ctcaatatca tattccgcat 3481 gcttataatt ttctagttta tttatactaa ttctaaaagc attattaaaa aaattctgca 3541 attcttgtaa tttgtcagca gttacggtaa aacctgccgc catagcatga cctccgcctg 3601 ctattagcaa gtctttgctt ttagcattga taatttcagc accaaaatca atacctaaaa 3661 tagaacggca tgaagcttta ccaatcccgt catttaaagc tataactgcc accggcttat 3721 caaatttttc ttttaatttg ccggcaacga ttcctataac gcctggatgc catccttctt 3781 ttacgataaa taataaacta ctatcttgtt gtgtcaaagc aatttccatc gcttcttcta 3841 tcattaataa ctcaattact ttacgctcat tattatgttt ttcaagttct tcagctaatt 3901 tttttgcttc attagaacaa ctagtagata ggagattagc ccctaaactt gactttccta 3961 ctctaccgcc cgcattgata cgcggaccta gaataaaccc taaatgataa cattttggta 4021 tttcattaag ccctgccata tcatataatg ttttaatccc tatattttgc ctttgttgca 4081 ttattttcaa tccgcttgca acaaatgcac gatttaagcc tgttaatttc atcatatcac 4141 aaacagtacc aagagccact aaatctagat acttcattag attaggctga agcattgttt 4201 gcgtgaaata attttgcttc tttaaattcg ataatattgc agttgtaaat aagaaagcaa 4261 ctcctacggc tgccaaatgt ttatattcgc ttttttcatc aatacgattt ggatttacta 4321 tagctactgc atccggtaat atttccgtag ttatatgatg atcgattact ataacatcaa 4381 ggttaacgtc ttttgcgtat tttagggctt catgtgccat agcaccgcaa tcaaccgtaa 4441 ttaataattc tgtgccgtta tctttaattt tttgcatagc aaaaggagtg ggaccgtatc 4501 cttcagctat acgatcggga acataaatat cacatagtat atttaaatct ctaaaaatat 4561 ttttaagtaa agcggctgaa gtagcaccgt ctacatcata atcggcaaag atacatattt 4621 tttggttatt taaaatagct gtaacggttc tatctacagc cttttccata tcaagtagat 4681 gaaaaggatc aggtaataaa tttttgattt tcggtatcaa aaaattttct acttcctcta 4741 gattatttac tcttaatgat actatcctag caagtaaatc actaatttta aaactacgac 4801 ataattcggt gactatatct tcgttaatca gtttttgctg ccagatttta ccgtttatag 4861 atgcttgtgg tttcatttgt ttattaggct gtatttttgc tgtatatccc caaaagtttt 4921 ttagcttcat catctgcaat taaagcttca acaaactcat ctaattgtcc gtttttaact 4981 acttcgtcta tcttataaag tgttaagttg attctatggt cggatactct tccctgtggg 5041 aaattataag tacgtatccg ctccgaacga tctcccgaac ctacctgccc tcttctgcta 5101 tcggctcttt cttgttcctt tttccgccgt tcttcttcat aaattctagc acgtagaatt 5161 tttaacgcct ttgctttatt tttatgctgt gacttctcat cttgcaaggc tacggtaata 5221 ccggtaggga tatgagttat acgtacggca gaatcggtag tattaacgtg ctgtccacca 5281 gcccctgaag ctctataagt atcgattctt aagtctttat cttcaatttg aatatcaacc 5341 tcttcagcct caggaagtac tgcaaccgtt gctgccgaag tatgaatacg gccttgtgat 5401 tccgtttccg gtactctctg tactctatga acgcctgact caaatttgag cttagagaat 5461 acatctttgc cttttattga cgccgatgct tctttataac cgcctattcc cgtatcggaa 5521 attgctaata tctcaaaacg ccatcctttt aattcagcat atctttgata catattaaaa 5581 agtacggcag caaaaagtgc agcttcttct ccgccgcttc ctgctctaac ttcaataata 5641 gcacttttac tatccgcatc atctttcggt aataaagcaa tttttacggc tctttcaagt 5701 ttgggtaacg aattttcaag agtgtgtatt tcgtcttcaa tcatttctaa agtagcatta 5761 tcaagtccca cttctagctt aaaattattt gcttcttcaa gctcagattt agccttatta 5821 tattctttaa tttttgctac aacatcttca agttctgcat attctttaga tgccttaaca 5881 aactcgtctc ccataatgcc ggaagatagt ttgttgccta aattttcgta tttatctaaa 5941 atttttgcta aattatctga aaaacgcatg ttattttatt gtgatttgtt tatgggtgag 6001 atttcaacgt tattacgaga agaaactgaa agtttcaacg aagcaatctc aggatatttg 6061 acgagattgc cacgcagcct atggctgctc gcaatgacga cttatatcaa catcaaagcg 6121 ggactctcta taaacttttt aaatgctgcc aagaactcag caccgactgc tccgtctact 6181 actcggtgat cggcagaaag agttacgtcc ataattgttg ctatagtgat ttgatcattc 6241 ttgactatag cacgttttgc actagctccg acgcccatta tacaactttg cggtgggtta 6301 attatagcat tgaaattctt aataccgtac ataccgaggt tagaaatggt aaaccctccg 6361 ccctgaaatt cttcaggggt taatttatta tcttttgctt tctttattaa ttctttcatt 6421 tcacgagata gttctagaat gtttttttga ttggcatttt taactatcgg cgtaacaagt 6481 ccgttctcaa tcgctaccgc tactgaaata tcgacattat tataatatct aattgcatct 6541 tctccccagc tagcattggc atttggcact tcttgtaaag ctttggctac tgctaaaata 6601 ataaaatcat taaccgatat ccttgttgat ttatcttcag aaaaagattt attaatgtct 6661 tctcgtatat ctaacaattt atcgacatta cattctatag ataaataaaa atgtggaact 6721 gtttgtttag attcaaacag acgcttggct ataatcttgc ggatattatt atttggtact 6781 aaacgatatt cttcaggatt tctgctaact attttattat gagcagtgct aggagtatat 6841 gataagatat cctgtttgac tattctaccg tgtggaccgc tacctttcac gctctcaaat 6901 ctaatatttc ccatttttgc aagtcttttt gcaagcggtg aggcgaatat tttactagca 6961 tcatgtttta taactgttac ctgttcttct acattagcta ggttctcgtg gggtttcaga 7021 agattagcat ctgttttcgg tgacggtgat acactattat tttttgcaat aaacgcatca 7081 atgtccgttt tttcttctcc ctcttcactt aacacggcaa ttaaagagtt aacaggtaca 7141 ttttgactat tttgtgggat aactattttg gcaagtatac cttcgtctac tgcttctact 7201 tccatcgttg ctttatcggt ttcaatttca gcaattactt ctccaggatt aactttgtcc 7261 ccttcttttt ttaaccacct agctagattg ccttccgtca tagttggaga taaggcaggc 7321 attaaaattt taatcggcat aacttattta gatttgattt tttattgttg ttattacacg 7381 tcattgcgag gagagacaaa gcctcgacgt ggccacctca tgaaacaata aaattcctga 7441 gattgccaca ctctctacgt tcgcgtgcaa tgacgatttg agtagctatt gcaccttaat 7501 atcagggcta acgatcatta tcatctgctt gccttccatt ttagcatgct gatcgatttt 7561 aacgagtcct gcgagcccta tttctatacg tttaaatagt gcttgaccga cctctttatg 7621 aagaatctct cgtcccttaa accataaaga aatttttact ttatctccgt cttttaaaaa 7681 ttcttttatt ttttttagct tagtttcaaa atcacctata ctaatattag gtttaaattt 7741 catttcttta agtacgacaa ttttttgctt tttgcgtgct tcatgcaaac gttttttgct 7801 ttcgtactta aacttaccaa aatctagaat tttacagaca gggggtacag cattcggtga 7861 tatctcgact aagtcaagac cagctctttc cgccatatct aatgcttctc taatatttac 7921 gatgccgtgc atttcgccgt tttcgcttac taaacgaact tctttagctc tgatttctct 7981 attagcctta ggaaaattat ttttagaaat aaaatttctc cgtattatgt ttataaataa 8041 atatatattg catttaactg attttattta aaattacaag taaataaaat attttatctt 8101 taattttatt tagaaagttt taaaaaaaat tgaaacgaca aggcacattc caaatattaa 8161 taaacagatt cgtgttaatt tagtgactct tgcctgtatt ttcaagtttt ttaggtctat 8221 agcatgctta tgagcttgtt ctttttgtgc catatgcatt aattcctgta aagtaccggg 8281 ataaatactc tcatactcac tgattaaatc aattggcggt aatatatgtt caaatttttt 8341 atggtaaaaa ttattatcag gttcgtttac actaaaagtc ttagcataac ctttatttaa 8401 tctattattt ttgtaaaaaa aacgtttagt ctctttcata ttcctttttt attttttgaa 8461 atgtatataa tatattactt tcaactattt taaaataatc aattaattgc gtttcttttt 8521 tttgctgttg tttggagctt ttcatattta ttatattctt tagctctgca tatattagtt 8581 ttataaaact ttgtttcatt gattatactt ataaaatctg tttttggtat tagtggttgc 8641 ccctaaaatt tatagcatta ttaaatttat tgcacaacag gttataaaat ttttatcaca 8701 tccggcagta atttttactt cctcggcatc tttaacataa tccggtataa tatcctctaa 8761 tataatcaaa tcaccgaaat tgcttagaac tttactgtta aaacgatttg aaccgtaggc 8821 ataaaattta taaggagatt tcccaagtat aaaacgtaat attaacaaat cttgcttttc 8881 aatctgaacc actatatttc tccaaattat ttataagctc atttaaagca tcagaaaaat 8941 catcaaaaat actaattact agttctaaat ttttttcatt ataagtatga accgtaatgt 9001 tacgaatctc tataaattta aaccatattc tagggtcaga aatcaacccg ttaaccgctg 9061 ctgcccgaaa tacatccttt aaaatataag gtgttttgcc ggatttttca caaaagcgtt 9121 tcattgtttt ccaagctagt tcataacaaa attcaaaaga ttggatactg caggctttat 9181 tctgctcagt atctaaatgt ttacgcaact cttcgaattt ctgccttgat acttatatct 9241 agccctgcga ttaaatgcat tttatactcc tattttttgc tttaataatg cctgataatt 9301 cattaccaat tttgtactga ctaagtcttt gttagtgtga aactctattt tatttgtttt 9361 tataccagca acattttcaa atgagtgatg ctctatttta tcgcttattt tactagcaag 9421 gcttagagca atattacggt ttttatcatt agtaaaaata catattgcaa attccagcta 9481 cattatattt ttgtacatta gtagatatat tattaacatt caatatacat atatttccaa 9541 cgctattata tttaaaaatt tactcttttt ttcaacgtta ataattcatt taatttcaaa 9601 ttcccgttct ttaaataaaa tacgcatttt agtagtgata tttttaataa atcttatttt 9661 aaataaaaaa tatccttctg ttattatatg tccgaagctt atatttttct agagcaagga 9721 atttactatc gcatagtgat ttaatttcag catagcttgt taatttctct atccatctat 9781 cctcttccat ttctgtctcc tgcgatattt tttaaaaatt taatttaatg ctgaaaattt 9841 ttcacgactg tttttgtcat tttattacct tttaaattaa gtaagatgtc atcctcgctc 9901 acttgtaggc gttgcctgaa tggatcgttt atgtcattcc cgcgaaggcg ggaatccatg 9961 gtaaagcgag ataaatcgag tttttaatat taaaaattca atatatttat acctttttat 10021 tactgaatgc ccgccttcgc gggaatgaca tacaagtata tctaattaaa taccccactc 10081 ttaatagctt cttggttcac cacattaccc cctactctct ttacggcata aaactttaca 10141 aaaggctttt cagtgtaagg atcacgtata atattaatac cgcttctatc tactatttta 10201 taacctgctt taaagtcacc tatcgctata gcatttccct ttttatctat aggaggcata 10261 gcggagctac acactaccag tactccaaat atatttgctt aagggaatcg gatagtgaag 10321 actgccaaat aaaacgtcct tggtgatctt taagcttctg aacttcggat aaagtaatac 10381 gattcatgag caaagttgca ttcactaaat attctgcttt aagggagttt ataaaatcaa 10441 gcagcccatc ggcggtaatt ttattaccca tcttaatctt ctcgattgta tcatggtcag 10501 gtgataaaat atctctaggt ttttttatac cgtcaccatt gataaacgca ttattttcca 10561 ttttaacgaa gcaattatta tttttttctg tatcttcgcc taacccaaga atctctattt 10621 gttgtgcagt atttttaatt ctgtctgctg taagggaaca ggtggtggag gttctatcag 10681 cattattata ttttgtcggt tcatttactt tagaaagcag cattagcatg attaaactat 10741 cattttttta ggcttatcta atggtccact taattctaac gatgtatcag gttgcgttaa 10801 tagctccgga gtattagata tattgtgtga cgtgttatcg ataatactaa atatttcttt 10861 tatttcagta tcttttatac attcaataat agcggattca gcttcctttt ttattgcatt 10921 ggttattatt tatattttga cttggagctt ataataactc tcgtacattt tacagccaaa 10981 actttaagcc cttcagataa aggatcatca tttttataat ccaaaaccat acaattttga 11041 tcaccgcatt ttttccctat tgaaagaata aaatttccct taataatatc ttttttaact 11101 gatcagccgt tatagtaaaa ttgagataaa tagtaagttg tctccccttg cccgcaaaag 11161 aatgtttctt ttaatttttt gatgtaaatc acatataata ttttcgttct taggtgtcat 11221 ttctaatgta ttagtttctg atctaataag tagccggttg atgtctgtta tatattgatc 11281 tcgtgctgct gtaaacattg catcagaagt taatttttta tcttggttat tgatcattat 11341 ttttatccct ttattttttt aagatatggt acagtgtgtt gcgcctgtta gcccgtaatc 11401 atcattctta acatactctc tatattcttc tattggtttt gaagttatag attgagattg 11461 ggcgttatta gtaggcttta ttattgcttc tgtttcttga ggtttttgaa ttatagattt 11521 atgcttatct ttattgttac ctaatacggt aaattcattt attgcttctt tacattcaaa 11581 aacactttca tcggtaatta aatggtactc agtgggtaaa gtgctattaa aatctgttat 11641 aattgatttt aaattagaaa gaattaagta ttcaggaacg ggaattttac gccattctcc 11701 ctgtactgca ttcatatatc cattttctat tatagctagc tctttaagtt cagagtaatc 11761 agaatatcct aaaatctttt aaacatacag aatttgttaa cttgctatga tgtaaaaatt 11821 ttcctatatt aattacaatt tttattaaat tacttagttg ttccttatta attccaaggt 11881 gatttccatt tttataaaat tctgataaat atgtacaagc atcattactt cctaaaaaca 11941 tagcaccttg aaaatataac atggtatcta caaatttttc ttattgctta gaaatctctt 12001 cttccagtaa agcatcttga taagattttt tacctttttc atataaatat tcaagatccc 12061 tataatatat tacataaatt atattctgag gttattattt tatctcatct tcgtctatag 12121 ttattgagga tacaagccct gaatagtcta ttgttactgt tacaaatata cggaggctat 12181 caagagtgag attaaaattt tcaataattt catcctcgtt aattgcgaaa ggatcttcac 12241 tattttgctg ttgacatatt tcaatagttt ttacgtgagt aacaacactt ggtttgagaa 12301 atttttcatt aatatttact gacaataagg aggtatttat acatttttta tgcttaagtt 12361 ccgactaaga ccataatatc tctaaattgt gttatattta tattttgaag tccataatta 12421 ggcatttttt ttattacttc gtcatattaa ttctactaaa ccttcacatg cattattatt 12481 acccgtaaat aatgtacatt taaaagcttt ttcaatttta taaaaatctt gcattaatgt 12541 acgaatgtta ttagaagaaa gttttttaaa ttcgtttaat tgctcatatg catttgttaa 12601 aaacacttga ggcagataac ttgggttgtt attcccttgg ggcatatatt tattaccttg 12661 ttaaatggga gcttaagtag aagttaacaa aaattaagtc tacaatttaa atttagtaat 12721 atttttgcta aaaaaaagtt cggcagtgga aaaagagatt atttttttgg aaggtagttg 12781 caatattatt ctgccggtat tatcgatatc tttaaaaaga ccggttacta tatcattttg 12841 atatttaacg ctaatatttt catataactt ataagcatgt tctaaccatt tttttctaat 12901 aaaaggaaaa ccgttattat gccaaatttg ataatattct tcaaaatttt ctattaatat 12961 ctcaagtaaa gcttgcgctt ctataggtgg tagattttcg cttattaagc tagtagtagg 13021 ttggtcgata ttatcagggt gataggtaat attaatgccg ataccgataa taaggtaata 13081 attattttct actttaacag attcaagaag tataccggca attttccgac cgttaattaa 13141 tacatcattt ggccatttta gttgtataat gttattttcg ttccttatgt catgcctgct 13201 ttcgcgggaa tgacatagag cactatggga gtggcataaa gaggttatac tatcataaac 13261 gctaagtgcc gtaacaaaag ataattgcgg caataattct agctctttat caggctttat 13321 tagtaaactt acatgtaagt tacctgacct agactgccag tttttgccgc ttctaccacg 13381 tccgttagtt tgagatttgg caagtactgc atagtttgaa tcaactttag tattctgagc 13441 cattctaata gcctcagagt gtgtactgtc tagcttgtca aaaacaatta gcttaaattt 13501 accgatattc atttttttta gtagccgtca ttgcgaggaa aggcgagctt tgttgcatgg 13561 ctcgaaaaat ccgctcgatg tcattcccgc gaaagcagga atgacataaa aacacctaac 13621 tcacccccta ctgacatgac ttgtagctac actatgtttg ctttgaattt ttggtgcttc 13681 gcttttactc ttagttataa agctttctaa atcttgttta gtaaatttaa acttagcaat 13741 attttcatca aaggttttag ttttatcaaa tcttacatct tgatttttat ctattccaag 13801 tacctcaatg aaactatctt ttattttact tgaagcagca gtatcgttta aggtatacaa 13861 caaagcgttc aatgagtttg tatcggcttt tagtgtgtta ttacgactag ttgcagcaat 13921 aattacatat tctttaagct tttcatttaa ttctttttcg tttaatgctc cggttttaca 13981 aaatgataat aacatctttg ctttatcatt atgattttca ataactccgt cttgccattt 14041 agaagtatta ttttcttttg acggaataaa catttctaac aatttagtgc caaatgtttt 14101 atgtaaattt ttattatcat aaacttcata aacatttagt agaaattttt gatggtcaaa 14161 tattttatct gcttctttgc caaggtcatg attattcaaa tgttctctag tttgacaata 14221 tcctttaata tgcaaataat cagaatattt ttgtgcatct ttgaaatcca aagtatctat 14281 tccggcagta tctaaaacaa cagtgtttaa agcattttca cgcaactgct cattagttgc 14341 tcttagagtt tcagtatatt taaattttcc tcctactttt gcaagcgtct taaataatat 14401 atcagctaaa aactttacga tatcacttgg gctttcaaat ttttttgcac tatatatagc 14461 aatatttgca tcagcttcca tacccgtacc aaaagccata gctagagttc taccttgttt 14521 tttagctaag gtaatctcct ccatattatc agttactgct tttgtatcaa attccggttc 14581 attgccttta aaatattttg ttggtatatt atctctatat ccaccgtcga tatatttttt 14641 atcgtcaatt tctaccggct taaaaacaag cggtatagaa gcagaagcac ggcaagctaa 14701 agcaatttca acatttggcg tatcaaagct attgaaaata gttaattcac ttgtctcttg 14761 ctgagttgcc gtaattacta aatccttata ctgcactgga tcgtattttc gcagtaacgc 14821 tatatcctta aaatatattt taccgtcttt ttggttgtat ctttctctta attcatcaag 14881 agctttatca tctttaacat ttactatatc tgatctctgt aaaaattttc ctatattttc 14941 tttaataaca agttctaata gagcatataa aggtttaccg tctttattta actgtactat 15001 acccgcagaa aacccttttt ttccaagtaa agtttgcaga tttgtatttt tagaaatttc 15061 ttcaaatcgc tcaggcggtg tcccaagagc taccactgtg gcagttatag caccagcgga 15121 agaacctgct accgccttga cattatctaa aataccagct ttttttactg cttcataagc 15181 tccagaatat attgctccct tagctcctcc tccactaaaa gctatatatt cgataggagc 15241 tttctgtgct tgctctaact cctgcaatgt ttttgtttga ttgctagaag attgttgaat 15301 tttttgtagg tcttttaact cctctaatat atcagattgc tcattaacta caggagtttt 15361 tgactcttgc ttcagattat taataatagg atgttttctt accgttatat cagccatagt 15421 tttattttat taagttatct tctacaaact tccagttaat catatgctta ataaatatgt 15481 caacataatc aggtcgtttg ttacgataat caatataata agcatgttcc catacatcac 15541 atgcaagaag cggcttcata ccgtttgcta taggtgtacc ggcattagcg gtttttataa 15601 tttgtaacct attatcgtga tatacaagcc atgcccagcc gctaccgaac tgccctactg 15661 cctcttgctt aaactgttcg caaaactctg caaaactacc gaaatcttta ttaatttgtt 15721 ctaatatttt accgcttggc ttacctccgc cctgcggctt tattgaatgc caaaaaaagg 15781 tatgattcca tatttgggct gcgttattaa aaatagccgc atttgagttt tgtgatgacc 15841 attcgattat ttcttctaaa tctttttttt gtaattcttc tttatctttg agtaaattgt 15901 ttagattttg tacataaaca ttatgatgct taccatgatg ataatcaaaa gtctcgagag 15961 taaaatgtgg tttaaaactt tctttctcat aaggtaaatc aggtaagata aaaggatatg 16021 aggtttgatt agatttgttg caataggtca tgttattttc tcctatgtga gtttttatat 16081 atttatagcg agaatcagta cgtcattgcg aggaaaaatt gaaaattttg acgaagcaat 16141 ctcaggagtc ttactttatg agattgtcac actccttgca gttgctcaca atgacgattt 16201 agtatccacg caggaatgac atcaaagtaa cttatgaaaa tcggaagcta aataaagcga 16261 tccggttatt ataatatttg ctttattatc gccgtttatc ttctttatat cactaatcgc 16321 ttcttcgagt gagtcgcttg cgctaaaatc aataccactc tttctgcctt ccaaatttat 16381 tgtttctgca ctatggctta gtggttcgga taaaacttta acgccgtaac ctttaattgt 16441 caagccctta aagtaagagc aaaattcctc gatattccta ttttgagtca taccgagtat 16501 taaatatatc gatgatttta aattatcacg catccaattt gccaaaactt gagctccgct 16561 attattgtga gctgcgtcta tccaaatttg aacattatca cctattaatt tagaatattt 16621 tttcggttct attttttcga ttctagcagg ccaaatagta ttttgtaatc ctttagcaat 16681 aacctcatta ttaatattaa attgtttgtt aataaggctt attaaggcaa taacgcttgc 16741 agcatttatt aattgatgat caccaagtag cgaaggagtc ggaaactcat aggtaaaatt 16801 tcgtgatgaa taaataaatc cgttgcccgt ctttttaata ccgaaatcat attcataaca 16861 gaaactcggt acttctaact cgtcagcctt tgcaaataat gtttcataaa cttccaaagc 16921 ttgcatactt ataacgcaag gaacgcaaga cttcataata ccagctttct caactgctat 16981 taggggtaat gtattaccca gcatatgcat atgatcatgt gaaataggtg taactaaagt 17041 aattaacggt cgttctacta tatttgttgc gtctaaccga ccacctagtc ccgtctctaa 17101 aattaatata tcggcttttg ttttctcaaa tgctagaaat gctgctgccg tagtaccttc 17161 aaagaagcta ggttcaatat taaatttttc gcttgctacc ctcacctgct cacaaacctg 17221 ccataattca ttatctgaga ttttctcacc tgctactacg attcgttcat taaattctaa 17281 taaatgagga gatgtatagc aatgtacctt ataaccggca agcgtaaaga tgcttttaag 17341 catagcactg cttgaacctt tgccgtttgt acctgctata tgtatgacgg gaggaagcct 17401 taaatgagag ttacctaagg ctcttaaaag tcttgctata ttttcaagat catatttaat 17461 gttatttttc caggtcggca ctggaaaatg cggcattagc attgttattg attttttttc 17521 atgaatgata gagttatacc atatttgttg tcaacttaaa gatcgatgcc attcctgcaa 17581 aggtggtgtt tttgcatggc tcgaaaaacc tactcgatgt cattcccgcg caagcgggaa 17641 tccagggtaa agcgagataa atcgagcttt taaaaagctt aaaagtagcg aattcccgct 17701 tgcgcgggaa tgacatcgaa actttagatc cactgttttt aggcaatact gaagttcatc 17761 gagtttttgg ttttactgca ttgataagtc caattaataa tactgactta attattcccg 17821 gtattataaa aggtaatacg ccgccgtaaa atgcaccact tgctcctaag agtgtagaga 17881 gccacatcca gcctaaactc ataataatta tattaccgat caaacataaa gatatctgat 17941 ttaaccattt attagaagta aaaattttat cttttaagtt agccataaca tatacggcaa 18001 ttacaaaacc tgctagatat cctccggtag gaccgaataa tattcgtaaa ccgcttgaaa 18061 attctccgaa cacagggatt cccattgctc caagagttat gaaagataat attgttaaag 18121 gtgcggtagt cttattatat gtaagtccga tgaatatcac tgcaacggtt tgcaatgaaa 18181 taagtatagg ctttataggt attactattt gtgaacaaat agtaagtaat gccactccta 18241 aaactatttc tattgcttgc cttgtggtta actgtagtgc gattgaatta agttgcataa 18301 aattaccgca tgatttattt ttaagtaatt acactaaata gaattatata atgtccttgt 18361 caagaatata aaaatgaaaa taaaaattta taatgatcta ggagtttcaa aagaaagtat 18421 taagcattgt gtgtatacct taagacttta tgctccaaag tataacgtag attatattac 18481 tgcacaagaa attatagacg aaaagtgggt tcaaaacacc ttattactta ttttactcgg 18541 tggaagagat ttatactatg tacaaaaatt gcaaggcaca ggaaatgcta atataaagaa 18601 ttatattaaa aacggtggta attttcttgg gatatgtgca ggtagttact acagcggtaa 18661 ctatgtagaa ttcgctaaag gcacaaatat agaggttata agtaaacgag aattaaagat 18721 tttcaatgga acggttagag gaccattgct tgcgccttat tattacaatt cacataaagg 18781 agcaagagcc gcttatctaa aaataaatcc aacacttaat ttaaatatta aggattgtta 18841 tgctttttat aatggcggtg gatattttat tgatgcagaa aataccaaag atactgaaat 18901 aatagcaagt tatgaggatt ctcaggctgc aataataaaa tgtacttacg gcgacgggac 18961 agctatttta agtggagttc atcttgaata tgagcctgca ctcataaaca atcaatctct 19021 taataatatt cgtaaaatac taaaagctca tgatacggaa agaatcaaat tattaaattc 19081 tatattagac ttcttcggaa actcgcttat agagaggaat ttgtaggaaa cacgcagcac 19141 agcaccgcag cgtacataga agtacgtgag gatgcgagca gcgaattgac gcacaaatta 19201 cctctagaag tagagtttcc gaagaagtc //