LOCUS NC_016584:17 18300 bp DNA linear BCT 06-SEP-2013 DEFINITION Desulfosporosinus orientis DSM 765 chromosome, complete genome. ACCESSION NC_016584 SOURCE Desulfosporosinus orientis DSM 765 chromosome, complete genome. COMMENT locus start: 3826300; locus end: 3844599 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.509857; n0_4mer:D = 27.784533; n0_4mer:PS = 26.367402 FEATURES Location/Qualifiers source 1..18300 /organism="Desulfosporosinus orientis DSM 765 chromosome, complete genome." gene complement(-81..23) /gene="" /locus_tag="" /db_xref="3826218..3826322" CDS complement(-81..23) /gene="" /product="hypothetical protein" /translation="MCCFCSTDSSVNGGMQYGSKFEEITKERGMLNYL" gene complement(1..2826) /gene="" /locus_tag="" /db_xref="3826300..3829125" CDS complement(1..2826) /gene="" /product="signal transduction histidine kinase" /translation="MLDGIVYTDMEQCQACSACLRVCRTKSIMMKEGKSKIIEESCLN CGACLKACSRGAKKYQSGLEAVEELLAKDKSAIILAPSYVIVAQKRYGCSPEQFGTAL RKLGFALVYEASFGADVVTKVYLNYLWDFLNTQGREKTHVITSPCPSLMNFMEKHAPS LLDEFAPIMSPMAAQAVLVKQWNQGQVRIVGASPCMAKKSELLDPELGLYDQKLTFEE LIQLLDRRGIVPACLEETEFDGIQALYGAGFPISGGLTKALEPFSGELGFNLLSNDYL IIEGEDRSTNFLKQMARHKQGSGGLAGYPLLIDILFCEGCIMGKSLGVEGDYWENKRL ITDYTKKRFQKLQENSQECQGYITLVKNTVEVPEFQRWLAIVEELIADNQFTRPWQSR EYHRKEPAEEVLRGILELDGKHTREDELNCGACGYETCRERAIAVYNGENEPGGCIVH VKYEAKLSLEENKRLLELDQLKSDFLSTVSHELRTPLTSVLGFSNIIKKKFEDTIVPL VNGDDKKVKRTVQQIADNVEIIISESRRLTNLINDVLDLSKMEAGKVEWQMESISLEE VIARAIAATSSLFEQKGLELKTDMEELPLIQGDKDRLIQTVINLISNAVKFTDQGSIT CRARVTGDEITVSVIDTGIGIAAGDLPKVFEKFKQVGDTLTDKPKGTGLGLPICKQII AQHGGRIWVESEIGQGSTFLFTVPLDKEKGDQLNRLDIDNLVKQMTEQVSSDVRSQSR EQKNVLVVDDDANIRMLLRQELEAAGYAVREAGDGIEAIKMINQSKPDLILLDVMMPG ISGFDVAAVLKNDPGTMDIPIIIVSIIEDKERGFRIGIDRYFAKPINTDALIKEIGLL IANGASRKKVLVVDEDTSTLKTLVDVLETKGYAVVSARDNEDCLKKAQEEKPDMIIVD TVFSRRHNMVKTIRLEKGLENVLFLFY" gene complement(2873..10021) /gene="" /locus_tag="" /db_xref="3829172..3836320" CDS complement(2873..10021) /gene="" /product="amino acid adenylation enzyme/thioester reductase family protein" /translation="MEEQKVVYPLTNAQIRIWETEQFFKGTSIANIGGALYLKEETDF AVWEQCINKLIERNDSLRIRIVETNSGPKQWIEPYRYQRIEQVDFTGKLRKEQETWLT NRLQIPFEVYAEPLYTFISIKAWDGYSGVFLKIHHMLGDGWTIGLLSTQIMAEYARRT GKANDPDSLEYSYLDFIKSEQEYLHSGKYEKDREYWLEKFKLKPELMAVKPKNSLYYS AEAKRLTYAIEAEEAGMIRDYCKAYSTSPAILFEAALGIYLQRLHDLKRISFGVPVLN RRGVKELSTVGMYVSTIPIQIELDEKVSFADLCKQLGKEHFQCFRHQRYPYNRMLAEV RELHGIHDNLYDVSVSYQNAKIDKTKYSYDFKTVWYFNGYQTESLCLHIDDRDDAGVF VLHIDYLRELFQTDEIDDIYRRIMLILWQAISDGSQRITDLELVDGRERQKLLKEFNQ TKADYPRDKTIHQLFEEQAVRTPDQTAAVFEGESLTYEELNSRANCLARLLREKGVGR DKIVGLMPERSLEMLVGIMAILKAGGAYLPIAPETPGERIGYMLEDANAVLLITHEHL MNRVSSQWEVLDLSSEFIAGEKSFNLENVNLPRDLAYVMYTSGSTGKPKGVMIEHRSV LNLCAWIKDFYKLEENKNILSTTRISFDVSVEELLGGLLSGGTVFIGSKGLMLEPEKL ITFIQENKINIAQFVPATLHSLLRVKKITSLRVVVCGSEKLNDGLKDKILGMGYELFD GYGPTEATVEVTIARCEPGKSTIGKPIANNSIYILSGGRGIQPVGAAGEICISGIGLA RGYLNRPELTAEKFMANPFLPGERLYRTGDLGRWLPDGEIEFIGRIDHQVKIRGYRIE LGEIEALLVKYEGIKEAAVTAREDETGSKYLCAYFVSYLEVTATELREHLAQRLPDYM LPSFFIPLPKLPLNPNGKIDRQRLPEPEGSIQTGADYVPPSTETEIRLARLWEEVLGF EKIGVNDSFFELGGHSLKAAILASKIGKEFKVEFPLREIFTAATIREEADYIDKAAES WARDLAAAEKRDFYPASPAQRGLYLLNHMDKNSTSYNMPGAMKIEGNLDEVKLKRVFK KLVQRHEAFRTSFHLRGAEVVQKIEDHLEFTVEAEELEEGDLSQVMTGFVRPFDLSQA PLLRVQLLKVIREEPGILSPPAMYYLLLIDLHHIISDGTSLAVLVRDFISFYKGEELP ELSLQYKDFAVWQNKQLDSQKVRKQKEYWLNSFQGRIPVLELPADYPRPAFQNFAGDV VEFTVNKELTAGLKKLAAEKSATLYMLLLAAYNLLLYKYTGQEDIVVGSPIAGRQHPD LGGIIGMFVNTLALRNYPEGRKSFAEFLEEVKERALLAYENQDVQYKDLVEELGLKID LSRNPLFDTMFIFQNMDSCEPEIEGLRFTGQSMGLRTAKFDLTLTGEEVGEEIHFELE YCTKLFKQETMLRFVRHFTNILKAVTENPELRLADLDILAEEERGQLLWEFNQTKVDY AKDKLIHQLFEDQAEKTPENIALVFAERTITYGELNSRANGVAQVLRGKGVGPESIVS LMTEPSVEMIVGIIAILKAGGAYLPIDPEYPEERIGYMLADSQAKVLLTQRSLQGLLE RITYPGEVIDLSSPELVLGSREAKNLGNLENLSSPEDLAYVIYTSGSTGRPKGVLVEQ RNLLAYVMTFNQEFELTGEDAVLQQASCCFDAFGEEIYPVLLKGGRLVLARRAEVRDV NLLAGVINRNSISLISCSPLLLNQLNTLTGLRSVHTFISGGDVLKGDYIDNLLQRGAQ VYNTYGPTEATVCASYHRCLPGEKGLVPVGKPIANYRIYILDPDNNLSPLNIAGELCI AGEGVSRGYLNRPELTAERFVENPFVPGERMYRTGDLARWLPDGSIEFLGRIDQQVKI RGFRIELGEIEAPLLRLAGVKEAVVLAREDNSGGKYLCAYLIGEGEIGVPELRKHLAQ ELPDYMIPSYFLQLEKLPLTPSGKIDRQALPEPKESINTEAGYVPASTETEIRLARLW QEVLEVERIGVHDNFFELGGHSLKATLLVLKVQEEFGLTIPLVTMFSEGTIALLAGYI DAVRASVKPVVKADVKSDVKPAVKPDLSLVSDPKLVLLKAVDGVRENLFLIHDGSCTV EGYVEFSRRLEVEANVWGIKGAEAENMILPGITIADLAADYLKTIKKVQPEGPYSLAG WSSGGGIAFEMALQLESAGERIRFVSMIDSPPPGNADSGSELKGFMEMWEKLEGQLKE DLEGQTEEPFEKLPEGVAQAGARAGNGIPENGIPGAVFKLMSDYRTLNYQDRARRLKV VKAVLAAEISYQPAAKLQAELVYIGASESKVIPNQPWSGDCEKPVRYVEVKGDHFSIF KSPDVIGLTTAFAWNFQP" gene complement(10151..14851) /gene="" /locus_tag="" /db_xref="3836450..3841150" CDS complement(10151..14851) /gene="" /product="ATPase" /translation="MLALSGYTIDEKIHENSRIRVYRGWRTRDSQPVVIKALKEEASN PLGISRLIYEFEITRSLDSHGIVKPLQMEQEGTVFALVMEDNGSVSLREYLRLKPIHI PGFLDIAEQLAETLGRLHQQGIIHQDLKPENILIHPETGKVTIIDFGTAVLWGTYEYN ASIFHPPAGTAQYMPPEQAGRIEGDVDYRSDFYSLGVVFYELLTGRLPWQAGDSEEWV HVHIACKPKFQETDFSVQPIWAILLKLLAKTADDRYQSAYGLLQDLRECRLQFSQKGT IEEFPLGRLDISLSLQLPRKVYGREREMATLQAAFASVCAGQTRIILVSGYAGIGKTM LVREVLEPYAAKKAYFITGKFDQLRQNRPYAPLAAAFGNLVKQLLTENQAALDRWKKR ILRTLGRSGTVITELIPEMEWLIGTQPQAEVLPPMEAQNRFLMVLRDFMRVFARKERP LVLFLDDLQWADSASLQFLQYLSRDDDLSNFLFVGAYRDNETNQTHPLVTVLENLRND EIPVQHIELSGLGYSQVAEFLGETLHCSPEISAPLAEVLYRKSGGNPFFLSQLLKFLH REKLLYFNMEAGCWDWQLHPIQNLQMQDDVVGLILEKLQKLPRESQELLKTAACIGSR FDLNTLSIAGEITGNELSSRLLPAVLEGFVLTAEKGRYTGNQDQTIGAEDYEFLHDRI HQAVYSLLEEEEKKARHLKIGRLILQQTYQDKLDEKILSVMDHFNRGLELISDPEERQ RLAEHSLSAGCKAKKATDYGSAVGYFRAGMQLLPEDAWNSCRDLSFNLHMERAQCEYM GGDVVAAERLFDAALKHAATDFQRVDIGSLKMLLNAGMGNYTEAVGIGLKALGQYGIS LDLYPGKFHFAKALLVYKWHMYGRMITALADLPEIKNPVNRKVAELLIRLACVSSTSY TDLYGLICIMSGNYALKYGNSEMASIGYIGYSIVEGSILGNYQSGHELARVSLQLAEK YDLSFTKCIVYFTVGAMISHWTQHAETGLEYMSKAAEYGVEAGDVLIIGYALSTILES KYIMGTSLDEIAKEAKKYRNEARRLKHEAMDRSVAIYQYTTASLRGREEGLSETADDN SDESSFLDLIKEDKVSLVCYHFSRLQRCYLFGDYKNALNEAKKMKAFLDAIMGFMLTA EGNFYHSLTITAIYEELPPREKRKYAKILKHNQKKMKKWADACPENFLHKYLLVAAEA ARLTNKGQKAMALYDQAIRSAHENGYTQNEALANELAARFHFAKDRDKIARVYRTDAC RGYAKWGALEKVKALQQQYPHLREERFVQEIKTNSVEILNKVLYSSDASSSEQVGPTD MDILQKAIQHITEETDSDQLLRGFLGLAVRIAGADRGYLILEKDGQLFIEAGRLEERQ TITVQEPVAVERCECLAKGIVRYVARTLEIVVLNDKDRTGIFAADDYLMQGQVKSTAC LPVLFQGIPVGVIYLENSLLERAFVPERLELLKLLSAQLATVKKLQDYLEGKQEERKQ AAVPLVEPLTAREIEVLQLITEGLSNKEIAETLVLSNNTVKSYVKNIYGKLGANRRVQ VAARAKELNLVQRK" gene complement(14895..15402) /gene="" /locus_tag="" /db_xref="3841194..3841701" gene complement(15727..17562) /gene="" /locus_tag="" /db_xref="3842026..3843861" CDS complement(15727..17562) /gene="" /product="diguanylate cyclase domain-containing protein" /translation="MRKTIPSILVIIALIILVSATLFYHKPTAAQPPKPRNGVLDLRD WSFEKNGMVCLEGTWSFYFNRFLTHEDFVNGVDVMPTPIEIPSTKESMAHFKPFADNK FYGTLRLVIKLPEGTQTYGLRTNIILTAFKLYIDGNLNGEVGKVGTSGENSLPYYDIL TTYFTPENHEVELIYHTSDFTAQDCTIVAPKIGLASQISREVQLGLGRDLFLFGMLLI MGIYHFGLYMMRTKDRAPLYFGVFCLLFSLRMLLVGERFLPNHVHLSFFVYGRIAYLS VFVGFAALCGFLYYALDGLFAKWFVKISVVLGVLFGFLILWIPYNTADWLLIVYAVAG FLLLCYAIIRLVVGVLEGVPFANIVLLGFTFLGITFINDFIYQITLANTPSLIPFGVS VFTFTQAYSLSAKFSNAYTRAEQLAEENKAILSELKLMNSNLESLVKERTSDLEKALE EMEVMSKTDYLTKLPNRRLVLVKIKELIDKKKDFYIGLADIDHFKDINDQFGHVKGDE ILVLLSEILKATIGGCGFVGRWGGEEFLIVLETERLDTIYDKANEIRRAAAEYRHADI GKNITITMGLCRYRENIPLDILIASADEALYKGKLAGRNQCVISA" gene complement(17573..17959) /gene="" /locus_tag="" /db_xref="3843872..3844258" CDS complement(17573..17959) /gene="" /product="" /translation="MIREIAYNDIQVDVKQHYDTHFLVKCLNCSLQPRELEQLKEFIY KVHDRGFPNAENALKYYLEGRSFNKPSPDTEVFCSELTAETFMAMGFISTKYVANGYC PDDFNKDDNMPSLQPFYFYNGARLNK" ORIGIN 1 tcagtagaac aaaaacaaca cattttccaa ccccttctct aggcggattg tcttcaccat 61 attatgcctg cgggaaaata ctgtatcgac aataatcata tccggcttct cctcctgggc 121 cttttttaga cagtcttcat tatccctggc ggagacaacg gcgtacccct tcgtttccaa 181 tacatccacc agagttttta aggtggatgt gtcttcatca accaccagca cctttttccg 241 ggaagcccca ttggcaatga gtaagccgat ttccttaatc agggcgtcgg tattgatggg 301 tttggcaaaa tacctgtcaa tgccgatgcg aaagcctctt tccttatctt caatgatgga 361 gacaataata atggggatat ccatagtacc gggatcattt ttcagcacgg cagccacatc 421 aaaaccgctg atccccggca tcatgacatc cagcagaatt aaatccggct tgctttgatt 481 aatcatctta atggcttcaa tgccatcccc ggcttccctt accgcgtatc ccgccgcttc 541 aagctcctgc ctgagaagca tgcggatatt ggcatcgtca tctactacca gaacattttt 601 ctgttccctg ctttgagagc gtacatcgct gctgacctgt tcagtcattt gtttaaccag 661 gttgtcgata tcaagtctgt ttagctggtc tcccttctct ttatccagag gcacggtaaa 721 taggaaggta ctgccctggc cgatctcact ttccacccag atccgcccgc cgtgctgggc 781 aatgatttgc ttgcagatgg gcaagcccag accggtgccc ttgggtttat ccgtaagggt 841 atcccccact tgcttaaatt tctcaaaaac cttgggcagg tctcctgccg ctatccctat 901 gcccgtgtca ataacactga cggttatttc atcccctgtc accctggctc tacaggtaat 961 tgacccctga tccgtaaact tcactgcatt ggagatcaga ttaatcacgg tttgaattaa 1021 cctgtccttg tccccctgga tcagcggcag ctcttccatg tctgtcttca gctccaggcc 1081 cttttgctca aacagggagg atgtagcagc aatggccctg gctataacct cctccaggga 1141 aatggactcc atctgccatt ccacttttcc tgcttccatc ttggagagat caagaacgtc 1201 attaatcaga ttcgtcagcc gcctgctttc ggaaataata atctccacat tatcggcaat 1261 ctgctggacc gtgcgcttta cttttttgtc atccccattg accagaggga cgatggtatc 1321 ctcaaacttc ttcttaataa tattggaaaa ccccaggacc gaggtcaggg gagtccttaa 1381 ctcatgggaa accgtggaca aaaagtcgga cttgagctga tccagttcaa ggagccgttt 1441 attctcttcc agagatagtt tggcctcgta tttgacgtgt acgatacagc ctccaggctc 1501 attttcaccg ttatagacag caatggccct ttcccggcaa gtttcataac cgcaagctcc 1561 gcagttgagt tcatcttccc gggtatgttt gccatccaat tccaaaatgc ctcgcagcac 1621 ctcttctgct ggctcctttc tgtgatattc cctggactgc catggcctgg tgaattgatt 1681 gtccgcaatc agctcttcca cgattgccag ccagcgctga aattccggta cctccaccgt 1741 gtttttcact aaagtgatgt atccctggca ttcttgagaa ttctcctgca gcttttgaaa 1801 tcgttttttg gtatagtcag tgataagccg cttgttttcc caataatccc cttctacacc 1861 caggctttta cccataatgc atccttcgca aaacaagata tcaattaata gcggataacc 1921 ggccaacccc ccgcttccct gcttatgcct ggccatttgt tttagaaaat tggtactgcg 1981 gtcttcaccc tcaatgatca agtaatcatt gcttaataga ttaaagccca attcgccgga 2041 aaagggttcc aaggccttcg tcagccctcc ggatatgggg aaaccggcac catataaagc 2101 ctgaatgccg tcaaattccg tttcctccag gcaggcagga actattcccc gcctgtccag 2161 cagttggatg agctcttcaa aggtcagctt ctgatcataa agccccagtt ccgggtccag 2221 cagctccgat tttttagcca tacagggact ggcacccaca atccggacct gcccctggtt 2281 ccattgcttg accagcactg cctgggcagc catgggactc atgatggggg caaattcatc 2341 caggagagag ggagcatgtt tttccataaa attcatcagg gaaggacaag gactggtgat 2401 tacatgggtt ttttctctgc cctgggtatt cagaaaatcc cagagatagt tcaggtagac 2461 cttggttacc acatccgctc caaaactggc ttcatagacc agtgcaaaac ccagttttct 2521 taaggcggtg ccgaattgct ccggtgaaca gccgtacctc ttttgggcaa caatcacata 2581 ggagggagcc aggataatag ctgacttatc ctttgctaat aattcctcaa cagcttccag 2641 cccggactgg tatttcttgg cccctctgct gcaagcctta agacaagccc cgcagttcaa 2701 gcagctttct tcaatgattt ttgacttgcc ttccttcatc ataatggact tggtcctgca 2761 aactctaagg catgcagaac aggcctgaca ttgttccata tctgtatata caattccatc 2821 gagcatggtc aagtactcct ctcttgcttc ctctctgttc acaagcacaa cttcagggct 2881 gaaaattcca ggcaaaggct gttgtcaggc ctatgacatc cgggctttta aagattgaga 2941 aatgatcccc ctttacttcc acatacctga cgggtttttc acaatccccg ctccatggct 3001 ggttaggaat aactttggat tcactggctc caatatagac aagttctgct tgcagcttgg 3061 cagcaggctg ataactgatt tcagccgcta agacagcttt aacaaccttt agtctccggg 3121 ccctgtcttg gtagtttagg gtcctataat cggacatcag cttaaatact gccccaggaa 3181 ttccattctc aggtatccca tttcccgctc ttgccccggc ctgcgccacc ccttccggaa 3241 gcttctcaaa aggttcttca gtctgccctt caagatcctc tttcagctga ccttcgagtt 3301 tttcccacat ctccataaag ccttttagtt cactccccga atctgcattg ccaggaggcg 3361 gggaatcaat catagataca aagcggatcc tctcccctgc actttcaagc tgcaaagcca 3421 tttcaaaggc aatcccacct ccactggacc agccggctag ggaataagga ccttccggct 3481 gcactttctt aatggttttc agatagtcag cggccagatc tgctatagtg atgccgggca 3541 gaatcatatt ctcagcctct gcccctttaa tgccccatac attggcctcc acttccaacc 3601 tgcggctgaa ttccacatac ccttctacag tgcagcttcc atcatggata agaaacaggt 3661 tctctctgac tccatccaca gctttaagga gcacgagctt tgggtcagaa accaggctga 3721 gatcaggttt tactgccggt ttcacatccg atttaacatc agctttaaca acgggtttga 3781 cgctggctct gacagcgtct atatagcccg caagcaaagc tatggttcct tcagaaaaca 3841 tcgttaccag gggaatagta aggccaaatt cctcctgtac ctttaagaca agcaaggtgg 3901 ctttcaaaga atgcccgccc agttcaaaga agttgtcgtg gacccctatt ctctcaactt 3961 ccagtacctc ctgccataac ctggccagcc gtatttccgt ttccgtggag gccgggacat 4021 acccagcctc tgtgttaatg ctttccttag gctcaggcag ggcctgcctg tcgatcttgc 4081 cgctgggagt caggggcagc ttctccagct gcaggaaata ggaggggatc atgtaatccg 4141 gcaactcttg agccaggtgt ttccttaact ccggcactcc aatctccccc tcaccgatca 4201 ggtaggcaca aaggtatttg ccgccgctat tgtcctccct ggccagaaca acagcctctt 4261 tcactccagc cagcctgagc agcggggctt caatctcgcc cagctctatc ctgaaacccc 4321 tgatcttgac ctgttggtca atccgtccca ggaattctat gctgccgtcc ggcagccagc 4381 gggccagatc accggtcctg tacatccgct ctcccggcac aaatgggttt tccacaaacc 4441 tttccgctgt aagctcaggc ctgttcagat agcccctgct tacaccctcc cctgcaatac 4501 acaattctcc cgcaatattc agcggtgaaa ggttattgtc cggatcaagg atgtagatcc 4561 tgtagttggc aatgggtttg ccgacaggga ccaatccctt ttcgccaggc aggcaccggt 4621 ggtaactggc acacaccgtt gcttccgtgg gaccgtaggt attgtaaacc tgtgctcccc 4681 tttgcaggag gttatcaatg tagtcgcctt ttaagacatc cccgccgctg atgaaggtat 4741 ggacactcct taaccccgtc agtgtgttca gctgatttaa caataagggt gaacagctga 4801 ttaggctgat tgaattcctg ttgatcaccc ctgccagcag gttgacatcc cttacctctg 4861 ccctcctggc cagcacaagc ctgccgcctt tcagcagcac ggggtagatt tcttcgccaa 4921 aggcatcaaa gcagcaggaa gcctgctgaa gtacagcgtc ctcccccgtt aactcaaatt 4981 cctgattaaa ggtcatgaca taagccagca ggttcctttg ctcaactaaa acacctttgg 5041 gacgtcccgt cgatccggag gtatagataa cataagctaa atcttcaggg gaactgagat 5101 tctccaggtt acccaggttt ttagcctcac ggctgcccaa caccagctcc ggagaagaga 5161 ggtcaataac ttcacccgga taagtaatcc tttccagcaa cccctgtaat gacctttggg 5221 tcaaaagcac cttagcctgg gaatccgcca gcatatagcc tattctttcc tccgggtact 5281 caggatcaat gggcaggtag gcgcccccag ctttcaagat ggctataatc cccacaatca 5341 tctcaacaga aggctccgtc atcaggctta cgatactctc cggccctact cccttccctc 5401 tcaatacttg ggctacaccg ttagctctgg agtttaactc tccataagtt atggtccttt 5461 cagcaaagac cagggcaata ttctccggcg tcttctccgc ctggtcctca aagagctgat 5521 gaatgagttt atccttggca tagtcaacct tcgtctgatt aaactcccag agaagctgtc 5581 ctctttcttc ctcagccagg atatccaggt cagcaagtct tagctccgga ttttctgtaa 5641 ctgctttaag aatattggta aaatgccgga cgaacctcag catagtttct tgcttaaaaa 5701 gtttagtgca atattccagt tcaaagtgga tttcctctcc cacctcttct cctgtgaggg 5761 taagatcaaa cttagccgtc ctcaggccca tactctgccc tgtaaacctg agcccttcaa 5821 tctccggctc acagctgtcc atattctgaa aaataaacat ggtgtcaaag agcgggtttc 5881 tggacagatc aatctttagg cccagctcct ccaccagatc tttatactgc acatcctggt 5941 tctcataagc caggagggcc ctttctttta cttcctccag aaactcagca aaactctttc 6001 ggccttcagg gtaatttctc agggccaggg tgttgacgaa catgccgatt attcccccca 6061 gatccggatg ctgcctgcct gcgataggag atcctacgac gatgtcttcc tgtcccgtgt 6121 atttatagag aaggaggtta taggcagcca gcagcagcat atatagggta gcgctctttt 6181 ctgctgcaag tttctttaac cctgccgtca gttctttatt gacagtgaat tccacgacat 6241 cccctgcaaa gttttggaag gccggcctgg ggtagtccgc cggcagttcc aggaccggaa 6301 tcctgccttg gaaagagttt aaccagtatt ctttctgctt cctgaccttt tgggaatcaa 6361 gctgtttgtt ctgccataca gcaaagtcct tgtactgcag actgagctcc ggcagctcct 6421 ctcccttgta gaagctgata aaatccctga ccagcacagc taaagaggta ccgtcggata 6481 taatgtgatg cagatcaatg agcagcaaat aatacatagc cggaggtgag agaatccctg 6541 gctcctcacg aataactttc aggagttgga cccggagcag gggtgcttgc gagaggtcaa 6601 aaggtctgac aaatcccgtc ataacctggg acaaatcccc ttcttccagc tcctccgcct 6661 caacggtaaa ctccaggtga tcctctattt tctggacaac ttcagcaccc ctaagatgaa 6721 aggaggttct gaaggcctca tgccgctgca caagcttttt gaaaactcgt ttcagcttta 6781 cttcatccag gttgccttct atcttcatag ctccaggcat attgtagctg gtagaatttt 6841 tatccatatg gtttagtaaa tacagtcctc tttgagccgg agaggcagga taaaagtccc 6901 tcttttctgc cgctgccaaa tccctagccc agctctcagc ggccttgtcg atatagtccg 6961 cctcctcccg gatagtcgct gctgtaaaaa tctctctcag gggaaactct actttgaatt 7021 ccttccctat ctttgaggcc aggatggcag ccttcaggga gtgtcccccc agttcaaaga 7081 agctgtcatt gacccctatt ttttcaaaac ccagtacctc ttcccataac ctcgccaggc 7141 gtatttccgt ttccgtagag ggcgggacat agtctgctcc tgtctgaatg cttccctcag 7201 gctccggcag tctttgcctg tcaattttcc cgttggggtt cagaggcagc ttaggcaacg 7261 ggataaagaa agaaggcaac atataatccg gcagcctttg ggccaggtgt tcccgcagct 7321 cggttgccgt tacttccaga tagctgacaa agtaggcaca caagtacttg ctgccagtct 7381 catcctcccg ggctgtcact gccgcctctt taatcccttc atactttaca agcagggctt 7441 ctatttcccc cagctctatc cggtaacctc tgatcttaac ctggtgatct atcctgccga 7501 taaattcaat ttctccgtcg ggaagccacc tgcctaaatc tccggtcctg tacagcctct 7561 cccccggcag gaatggattg gccataaatt tttctgccgt cagttccggt ctgttcagat 7621 accctctggc cagcccaatt cctgagatgc agatttcgcc cgctgcgcct acaggctgaa 7681 tacccctgcc gccgctaaga atatagatac tgttattggc aatgggtttg ccgattgttg 7741 attttcccgg ttcacatcgg gctatggtca cttccactgt tgcttcagtg ggtccataac 7801 catcaaacag ctcatatccc ataccgagaa ttttgtcctt gagtccatca ttcagcttct 7861 ctgagccaca gaccaccact cgcaggctgg taatcttttt tacccttaac aggctatgga 7921 gagtcgcagg tacaaactga gcgatattga ttttattctc ctggataaag gttattaact 7981 tctcaggttc caacatcagc ccttttgaac caataaaaac cgtgcctccg ctcaaaagcc 8041 cgcccaatag ttcttcaacg gaaacatcaa aggatatcct ggtggtactg aggatatttt 8101 tgttttcctc cagcttatag aaatccttaa tccaggcaca caaattaagg acacttcggt 8161 gttcgatcat aacccccttg ggttttcccg tggaacctga cgtgtacatg acataagcca 8221 ggtctcttgg caaatttaca ttttccaagt taaaagattt ttctccggca atgaattcgg 8281 aggataaatc caggacttcc cactggctgc tcactctgtt cattaaatgc tcatgagtta 8341 taagcagcac ggcattagca tcctccagca tataccctat cctctcccca ggggtttcag 8401 gggctatggg caggtaggct cctcccgcct ttaagatagc cataatccct accagcatct 8461 ccagagaacg ctcgggcata aggcctacga tcttgtcccg ccctactccc ttctctctca 8521 gcagccgggc cagacagttg gctctggagt tcaactcctc ataagttaaa ctttcaccct 8581 caaatactgc cgctgtctga tcaggggtcc gcaccgcctg ctcttcaaac agctggtgga 8641 tggttttatc cctgggataa tcagccttgg tctgattaaa ctccttaagg agtttctgcc 8701 gttcccggcc atccaccagc tcaaggtccg taattctttg gctgccgtca ctgattgcct 8761 gccacaggat cagcatgatt ctccggtaga tatcgtcaat ctcatctgtc tgaaacagtt 8821 ctctcaggta atctatgtgc aggacaaaca cccctgcgtc atcccgatca tcaatatgga 8881 gacacagaga ttctgtctga tagccattga aataccatac cgttttaaag tcataactgt 8941 actttgtttt atcaattttg gcattttggt aggaaacgct gacatcgtaa agattatcat 9001 gaatgccgtg aagttccctg acctcagcca gcatcctgtt ataagggtat ctctgatgcc 9061 ggaaacactg aaaatgctct ttgcccagtt gtttgcaaag gtcggcaaaa gaaaccttct 9121 catccagctc tatttgaatg ggaatggtac tcacatacat ccccactgtt gacagctctt 9181 taaccccccg gcgattaagc accggtacac caaaagagat gcgcttcagg tcatgcagtc 9241 tctgtaaata gatacccagg gcagcttcaa ataaaatggc cggagatgtg gaatatgctt 9301 tgcaataatc ccgtatcatc cctgcttcct cagcctcaat ggcgtaagtc agccgtttgg 9361 cttcggcgga gtagtacaag ctgtttttag gctttacggc cataagctcc ggcttaagtt 9421 taaatttttc cagccaatat tcccggtcct tctcatactt gccagaatga agatactcct 9481 gttcactctt gatgaaatca agataggaat actccaggct gtccgggtca ttggcttttc 9541 ccgttcgcct ggcgtattcc gccataattt gagtgctgag caggccgatg gtccagccat 9601 ctcccagcat atggtgaatc ttcagaaaaa ccccgctgta gccatcccaa gccttaatgc 9661 taataaaggt atataaaggc tcagcataga cctcaaaagg aatttgcagc cggttggtta 9721 accaggtttc ctgttccttt ctcaattttc ctgtaaaatc cacctgttct atcctttgat 9781 accggtaagg ctcaatccac tgcttgggtc cgctgttggt ctccacaatt ctgattctta 9841 aagaatcatt tcgttcaata agtttattaa tacactgctc ccagacagca aagtctgttt 9901 cctctttgag atacaaggca cctccgatat ttgcaatgga agtaccttta aaaaattgtt 9961 ccgtttccca tattcgtatt tgcgcattgg ttaagggata aaccaccttc tgctcttcca 10021 tccgtatttc tcctccaaag ccttccttag gtttgactta gtaaaaacaa tggtttgcat 10081 cacctgcagc tttaacttac aaccgatttg cgcaaaaaaa accacccgaa tgggtggaaa 10141 gtgtaataat ctacttcctt tgcacgagat ttagttcctt cgcccgggca gccacctgca 10201 ctctgcggtt agctcccagc ttaccgtaga tatttttgac gtagcttttc acagtattgt 10261 tggaaagcac taacgtttcc gcaatttcct tgttggacaa tccctctgta atcagttgaa 10321 gcacctctat ttctctggcg gtcaggggtt cgaccagggg taccgccgcc tgcttcctct 10381 cctcctgttt accctccagg taatcctgca gttttttcac cgtcgccagc tgggcggaca 10441 aaagctttaa cagctccagc ctttccggaa caaaggccct ctccagcaga ctgttctcca 10501 gatatatgac tcctacaggg atgccctgaa atagaacagg caggcaggct gtggatttta 10561 cctgcccctg catgagatag tcatcggctg caaaaattcc agtccggtct ttgtcgttta 10621 acaccacgat ttcaagggtt ctggctacat agcggacgat ccctttggcc agacactcac 10681 acctttccac ggcaaccggt tcctgtacgg ttatggtctg ccgctcttcc agccggccgg 10741 cttcaataaa taactgtcca tccttctcta aaatcaggta tccccggtca gcacctgcaa 10801 tccggactgc caaacccagg aagcccctta acagttggtc cgagtcggtt tcctccgtaa 10861 tatgctggat agctttttgc aggatatcca tatcagtcgg accgacctgt tcgctgctgc 10921 tggcatcgga actgtacagg accttattta aaatctcaac ggaatttgtt ttgatttctt 10981 gcacaaatct ttcctcccgc agatggggat attgctgctg caacgccttc actttttcca 11041 gggctcccca ttttgcatag ccgcggcagg catctgtcct atatacccgg gctattttgt 11101 cacgatcttt ggcaaaatgg aacctggctg ccagctcatt ggccagggct tcattctggg 11161 tatacccatt ctcatgggcg gaccggatgg cctgatcata caaggccatg gctttctgtc 11221 ccttatttgt cagacgcgca gcttcggcgg ccaccagcaa atatttatgt aaaaagttct 11281 cggggcaggc atctgcccat tttttcattt ttttttggtt atgtttaagg atcttagcgt 11341 atttcctttt ctccctggga ggcagttcct cgtaaatggc ggtaatggtg agagaatgat 11401 aaaaattccc ctcggcagtg agcataaaac ccatgatagc atcaagaaag gctttcattt 11461 tttttgcttc gttgagagca ttcttgtaat ccccaaatag gtaacacctt tgcagccttg 11521 aaaaatgata gcaaaccagg gaaaccttat cctctttgat taaatccagg aaactgcttt 11581 catcagagtt gtcatccgcc gtttcggaaa gcccctcttc ccgcccccgc agtgaggctg 11641 tagtgtattg atagatggct acagacctgt ccatagcttc atgcttcaac cgtctggcct 11701 cattgcggta tttttttgct tctttggcga tttcgtccag tgaagttccc ataatatatt 11761 tgctttccag aatggtgctg agggcatagc ctatgatcaa gacatccccc gcttctaccc 11821 catattctgc tgctttgctc atatactcca gacctgtctc tgcatgctgt gtccaatggg 11881 aaatcatggc tccaacggta aagtaaacaa tgcatttagt aaaactcagg tcatatttct 11941 cggccagctg caggctgacc cgggccagtt catgacctga ctggtagttg cccaggatgc 12001 tgccttccac aatactatag ccaatataac ctatggaagc catttcactg tttccatatt 12061 tgagggcata attgccggac ataatgcaaa taaggccgta gagatccgtg tagctggtac 12121 tggaaacgca ggccagccta atgagaagct ccgcaacctt tctgttgacg ggattcttaa 12181 tttccggcag gtcagctaaa gctgttatca tacggccata catatgccat ttatagacca 12241 ataaggcttt ggcaaaatga aactttcccg gatataaatc caggctgatg ccatattgcc 12301 ccagggcctt cagtcctatg cccacagctt ccgtatagtt tcccatcccg gcatttaaga 12361 gcatctttaa gctgccgata tccacccgct ggaaatccgt tgccgcatgc ttcaaagccg 12421 catcaaacaa cctttccgct gccacaacat ctccgcccat atattcacac tgggcccgct 12481 ccatatgcag gttaaagctc aagtcccggc agctgttcca ggcatcctcc ggcaggagct 12541 gcatcccggc tcgaaaatag cctacagctg aaccgtaatc cgttgctttt ttcgctttgc 12601 agccagcgct gagactatgt tccgccagcc tctgccgttc ctcagggtct gagatcagct 12661 ccagtccccg gttgaagtga tccatcacgg acaatatttt ttcatccagc ttatcctgat 12721 aagtctgctg caagatgagc cggccgatct tcaggtgcct ggcttttttt tcctcttcct 12781 caagcaagga gtagaccgcc tggtgtatcc tatcatggag gaattcataa tcttctgccc 12841 caatagtctg atcctggttc cctgtatatc tgcccttctc cgccgtaaga acaaagccct 12901 ccaaaacggc aggcagaagc cgtgaactca attcattgcc ggttatttct ccggcgatgg 12961 agagagtatt caggtcgaaa cggctgccga tgcaggctgc ggttttcagc agttcctggc 13021 tttccctagg gagtttttgc agtttttcta aaatcagccc caccacatca tcctgcattt 13081 gcaggttttg aatggggtga agctgccaat cccagcaacc tgcttccata ttgaagtata 13141 agagtttctc cctatgaagg aactttaaca actggctaag gaagaatggg tttccgccgg 13201 atttccggta taatacctct gccaaaggag cagatatttc tggagaacag tgcagagttt 13261 cccccaggaa ctctgccact tgggaataac ccaggccgga aagctcaata tgctggactg 13321 ggatctcatc gtttctcaga ttctccagca cagtcaccaa gggatgggtt tggttcgtct 13381 cattatcccg gtaagccccg acaaataaaa aattgctcag gtcgtcatcc cggcttaagt 13441 attgcaagaa ctgcaaggaa gcagaatccg cccactgcag gtcgtccaga aacaagacca 13501 gcggccgctc tttcctggca aatactcgca taaagtctct taagaccatg agaaaacggt 13561 tttgggcttc catgggcggt aacacctctg cttgaggctg agttccaatc agccattcca 13621 tctcgggaat cagttcagta atcaccgttc cgctccggcc cagggtgcgc aagattcttt 13681 tcttccaacg atcaagggct gcttgatttt ccgtcaatag ctgttttacc aggttcccaa 13741 aggccgccgc caaaggggca tagggtctgt tttgcctgag ctggtcaaac tttccggtaa 13801 taaaataggc ctttttggca gcataaggct ccaagacttc ccgaaccagc atagttttgc 13861 caatacccgc atagccgctg actaagatga tgcgtgtttg tccggcacag acactagcaa 13921 aggcagcctg cagggttgcc atctctcgct cccgtccata gaccttgcgg ggtaattgaa 13981 gactcaagga tatatccagc ctgccaagag ggaattcctc aattgtccct ttttggctga 14041 actggagcct gcattcccgt aaatcctgca aaagcccgta agcactctgg tagcggtcat 14101 ctgccgtctt tgcgagtaat ttcaaaagaa tagcccagat gggctgaaca gagaaatctg 14161 tttcctgaaa tttcggttta caggcaatgt gaacatgtac ccactcttca gaatcccccg 14221 cctgccaggg cagccttcct gtcaataatt cataaaacac aacccccagt gaataaaaat 14281 cactgcggta atccacatct ccttctatcc tccccgcctg ctccggcggc atatactggg 14341 cagttcctgc tggaggatga aagattgagg cgttatactc ataagttccc caaagaactg 14401 ccgttccgaa gtcaataata gttactttcc ctgtctcagg gtgaattaaa atattttccg 14461 gttttaaatc ctggtggata atcccttgtt ggtggagccg ccccagggtc tccgccaatt 14521 gctcggcaat atcgagaaag cctggaatat gaataggttt gagtcggaga tattctcgca 14581 aagatacaga gccattatcc tccataacca gagcaaaaac cgtcccctcc tgctccatct 14641 gcaaaggttt gacaatacca tggctatcca ggctccgcgt aatttcgaat tcataaatga 14701 ggcgggatat tcccagagga ttggaggctt cttctttcag ggccttaata accacaggct 14761 gactgtcccg cgtcctccaa cctcgataaa ctctgattct gctattttcg tgaatctttt 14821 catcaatggt atatcctgat aaagcaagca ttattggcct ccacctcctt tgctgcatgt 14881 ctgctgatct acaatcattc ttcccataag caatataggc tgctgccgcc atttcttttt 14941 gcgctataca tggcctcatc actgcgtttg attgcagttt ctatagctgt attagtatct 15001 atctctgtaa tacctatact aacgctgata ttatataatt ccatttttat taaaaggctc 15061 tcgaattgtt tgaataattc tttgagctat gttttttatg tcttctaacc gcccgttaat 15121 aactataata aattcatctc cgccgtacct gcatattata tccgtatttc tcagaagatt 15181 ttttaatctt tggctagtct tctgtaaaat ataatctcct attttatggc catatgtatc 15241 attgatttct ttaaagcaat ctaagtgaag aaacataaga tatttatttt tgctattgtt 15301 gaaagaatca tttttatcga attccattat ataggttcta ttatacaaac ctgttaaagg 15361 atctctaatt accttttgat tcaagaatct gattttcttc gattatacat aagaattgct 15421 gaaatgtgat tagagaaaag caaatgctaa taatagcaca atagtaatta aaattatcaa 15481 taaaaaccat tgtttacgtc tcatgcatcc accatttttg ttattttatt atagttaact 15541 tcttaacatt atatctcaaa atataccaaa attcatcaaa aaactaactc ttataaatat 15601 tcaaaatagt aaatatacct ggctagcttg aatcaacaac tactttgagc ttttagagct 15661 ggagctgctt tagcagttgc agctttgaag gtgaggagac tctatgtttc aggtggctga 15721 cgtagcttac gcggaaatga cacactggtt tctgccggct aatttgccct tgtaaagagc 15781 ctcatcagca ctagcaatga gaatatccaa gggaatgttt tcccggtatc gacataatcc 15841 catggtaatc gtaatgtttt tgccgatgtc tgcgtgccgg tattccgctg ctgccctgcg 15901 tatctcatta gccttgtcat aaatggtatc caatcgctcc gtctccagta cgattaagaa 15961 ttcctcgccg ccccaccggc cgacaaagcc acagccgccg atagttgcct ttaatatctc 16021 ggataaaagg acaagaattt cgtccccttt aacatgcccg aactgatcat taatgtcttt 16081 aaaatgatca atatctgcta agccaatgta aaaatccttt ttcttgtcaa tgagttcctt 16141 gattttgaca agcacaagcc gtctgttggg caatttagtc aggtaatccg ttttagacat 16201 gacttccatt tcctccagag ccttttctaa atcggaagtc cgttccttaa ccagggattc 16261 aagattactg ttcattagct taagctctga caaaatcgct ttattctctt cagccagctg 16321 ctcagctctt gtataggcat tggaaaattt ggcagacaaa gaataagcct gagtaaaggt 16381 aaatacagaa accccgaagg gaatcagtga aggggtattg gcaagtgtaa tttgataaat 16441 aaaatcgttg ataaaggtta tccctaaaaa tgtgaaccct aaaagcacga tattggcaaa 16501 aggaactcct tccaatacgc caacaactaa gcgaataatt gcatagcata ataataaaaa 16561 tccagctacc gcatatacga tcaatagcca gtctgctgta ttatagggga tccagaggat 16621 gagaaaacca aacaatactc ccagaacaac actgatcttg acaaaccatt tggcaaatag 16681 tccgtccaac gcatagtata aaaatccaca caaagctgca aagcccacaa acacgcttaa 16741 ataagctatc cgcccataaa caaaaaagct gagatgcaca tgatttggca aaaagcgttc 16801 tcctaccaat agcatacgga gggaaaacaa gagacaaaaa actccgaaat agaggggggc 16861 ccggtctttt gtcctcatca tgtagagacc gaaatgatag atccccataa tcaacagcat 16921 accaaaaaga aacaaatccc tgccaagacc caactgtact tctctggaaa tctgagaggc 16981 taagccgatt ttgggcgcca cgattgtaca atcttgggct gtaaaatcgg atgtatgata 17041 aatcaattcc acttcatgat tttccggggt aaaataggta gtgagtatgt cgtaatatgg 17101 aaggctattc tccccgctcg tcccgacttt tcccacttca ccgtttaaat tgccgtctat 17161 gtatagttta aaggcagtca aaatgatatt tgttcttagt ccatatgtct gtgttccctc 17221 gggaagtttt ataaccagcc gcagggtacc gtagaatttg ttgtccgcaa agggcttgaa 17281 atgtgccatg ctctctttgg tgctgggtat ttcaataggt gttggcataa catcaacacc 17341 atttacaaag tcttcatgag tcagaaagcg gttaaaatag aaagaccaag tgccttctaa 17401 acaaaccatt ccatttttct caaatgacca gtcccttaaa tccaggacac cgttccttgg 17461 ttttggcggc tgggcggcag ttggtttatg ataaaataag gtcgctgata caagtataat 17521 tagcgctatt attaccaata tcgaagggat tgtctttctc ataatatcat ctctacttat 17581 tcaatctggc cccgttataa aagtaaaaag gctgcaggga tggcatattg tcgtctttat 17641 taaagtcatc ggggcaatac ccgtttgcta catattttgt agagatgaat cccatggcca 17701 tgaaagtctc tgccgttaat tcactgcaaa acacttccgt atccggtgac ggtttattga 17761 aagacctgcc ttctaagtaa tatttcaagg cattttcagc attaggaaat ccacgatcat 17821 gaactttgta tataaattcc ttaagctgtt ccagctcccg cggctgtaat gaacaattta 17881 aacatttcac cagaaaatgg gtatcgtaat gctgcttcac atccacctgg atatcattgt 17941 atgctatttc tctaatcata acttaatcat ccttttaatt tattaagcaa aatactttgt 18001 agcttactat ataacgggta ttttatacat ttaatgaaaa atttctttaa attataattt 18061 attttaacat cccgaccact attttccaat actaatgtgg cctaatagac atggtgacct 18121 ttcaatgtcc ctcaagagct aagtatttag gcccgtttgc atcttattgc aaacgggcca 18181 catgcggcgc acttattaat ttggattttt tagcaataag ttgatggaag agacatgata 18241 aaagcgggcg tacctttgta tattggtgtc aaagcaatca atacactaaa gtttgtggtg //