LOCUS NC_015732:16 18347 bp DNA linear BCT 11-OCT-2011 DEFINITION Spirochaeta caldaria DSM 7334 chromosome, complete genome. ACCESSION NC_015732 SOURCE Spirochaeta caldaria DSM 7334 chromosome, complete genome. COMMENT locus start: 2735753; locus end: 2754099 FEATURES Location/Qualifiers source 1..18347 /organism="Spirochaeta caldaria DSM 7334 chromosome, complete genome." gene 0..1229 /gene="" /locus_tag="" /db_xref="2735753..2736982" CDS 0..1229 /gene="" /product="hypothetical protein" /translation="MKSQNLIKLVKPVIIVFYLLFVCLIFAETTTTITDIEVQGLKRT NPIVVKNLLKAYINRDADKINTDEIIALLVATGIFENVTVSVKENTNQTVLFISLEEK WSIIPLPLVSIKSDSYVFGLGFFDANAFGLNHKLFSSASVSSKGPSIALGYIINSLWQ SKWDGVFSISYATKDETFTDVYEHEISTSDITSFSATISGNYSILNILKWDFGFEYQT KSYTDEQDTDLTSLGLQTGITLQSNAHWNGVFLTMSGVQFYYTWYYGIEGPSYGVFLT KGSYETAPVKNLKLSFRSVGLWGPQTPQLAEIGANKLGLIILPDTYTVYTMATFRSGL ELKLFSSGIVTFAGLAHYHIGYSEGSRTEPHIDYGPSFGLRLYLAKVALPAMDINIAY NQTTGLYQASFSIGMQM" gene complement(1274..3013) /gene="" /locus_tag="" /db_xref="2737027..2738766" CDS complement(1274..3013) /gene="" /product="flavocytochrome c" /translation="MRIKYFLHTIILWASVAFIGCVSTAPRFQPGTYEGEGKGHGGDI RVLVTVTETDIKDIKIMSMQETAFLGDTAFATLKDRILKANSTEVDVVSGATEASNGY ISAVQDALNKAGFVAVKKTKTQGRSKNLPAKSYDLVIIGGGGAGLSAANAAVAKGVRV VLFEKMGILGGNTIRATGGINAAGTAIQAEKGIKDSPDLFFQDTMKGGYNKNDPELVK TLATKSAASVSWLTDMGADLSDVGRLAGASVNRAHRPSGGAKVGPEIVKTLANKAKQS ATLSIFTDAEVRSLLTNKQGAVTGVVVRIDGKDYKVTAKAVVLASGGFGANNEMAAKF NPALKGFATTNHAGATGDGILMAQAIGAALVDMDQIQTHPTFAPDGNEMVTEAVRGNG AILVNSAGKRFVDELETRDVVSAKILAQEGKIAYLVFDNSVRKSLSAIESYLKAGFVL EAQNLADLAHKIGSTSETLEKTIKNYNDAVLSKKDTEYGRSDMPRTLSEAPYYAIKVT PAIHHTMGGVKINTSAQVLRTDGSVIPGLYAAGEVTGGVHGGNRLGGNALADIVTFGR IAGENAVAYIMKK" gene 3427..4281 /gene="" /locus_tag="" /db_xref="2739180..2740034" CDS 3427..4281 /gene="" /product="ATP phosphoribosyltransferase" /translation="MGKLRILIPKGRIFDNVSRLFAEAGIPISLSERTYRPNIAADWL DGKVMKPQNVGELLEIGSHDAGFTGIDWIRETGSNVVEVMDLGFDRVRIVAAVPAEMD EAALRGKKLVVATEYVNLAREWLTKKGYDFRILRTYGATEVFPPDDADMIVDNTSTGQ TLRDNGLRIVDTILESSTRFVASKIAMADPEKKAQIDELAMLFKAVLDGREKVMLEMN VNKIRFPDLVAGLPAMRSPTIAPLYGDDGYAVKVAVPRHEVPILIPQLKRLGATDIVE YELRKVVP" gene 4360..4965 /gene="" /locus_tag="" /db_xref="2740113..2740718" CDS 4360..4965 /gene="" /product="Imidazoleglycerol-phosphate dehydratase" /translation="MERIAEITRKTGETDIQVKLNIDGTGSAKIDCPVGFVTHMLTTF ARHGLFDIELTARGDLEVDQHHLVEDIGIVLGQAFAKALGDKGGINRVGSCLFPMDET LARAAVDLSGRPYLVFEANLSGLPLVSTEASFQTDTVEDFWLGFATNAACALHLDILR GRSDHHKIEALFKAAARAMREACSIDNRSLGQIPSTKGVLA" gene 4962..5624 /gene="" /locus_tag="" /db_xref="2740715..2741377" CDS 4962..5624 /gene="" /product="Imidazole glycerol phosphate synthase subunit hisH" /translation="VIGVLNYGAGNLGSVMNALARLGLPAQFVTGPEELQVRRGNNSG SSAGQQYSAIIFPGDGHFATAMEALTAQGYTEAIREWIAADLPFLGICIGLQLLFEQS EEAPPVQGKEIPGLSVIPGRVKKFQGPKVPQIGWNETKGTSRSRLFQNLPERSFFYYI HSYYVVPAEEDWVAAEADYYGTYCSAVERGALTAVQFHPEKSGALGLELLRRWAEVYH VS" gene 5614..6390 /gene="" /locus_tag="" /db_xref="2741367..2742143" CDS 5614..6390 /gene="" /product="Imidazole glycerol phosphate synthase subunit hisF" /translation="MLAKRIIPCLDVDDGRVVKGIKFEGIKDAGDPVELARCYNEQGA DELTFLDIGASYKSRDTLMEVVRQVAREVFIPLCVGGGIRTVEDMRLAMNAGADKVSV CTAALRNPALLTEMARAYGSQCVVLSIDAKRVSEPGEAPRWHAFAKGGREDTGIDAIQ WAIEAVRLGAGEILLNSIDADGTGAGYDLELTRRVGEAVPVPVIASGGAGNLDQIVQA LIPEGGNADAALVASMLHFGKTTIQEIKTYAEQKGVVVRW" gene 6384..7655 /gene="" /locus_tag="" /db_xref="2742137..2743408" CDS 6384..7655 /gene="" /product="phosphoribosyl-ATP diphosphatase" /translation="MVIASIDIQNGKVVQLKQGSQLMLEREDAAELAAEFDKYGEVAV IDLDAAMKTGSNDELVKSLLRRADCRVGGGIATVERAAELVSLGAKKVIIGSKAFRTS GDSFGINTAFLEALAKKIGRERVIVAVDARDGEIVVDGWKTPTGLPLIESAKALEPYV GELLYTCVEREGTMTGTNLDSIRSLREAVSCLVTVAGGVSTLEEIEAIARLGCDVQLG MALYTGKINLADAFIASLSWNQAWQEGKLLPVVAQAPDGQVLMLGYTDREALAETFKR GNLCFHSRSRNKLWMKGESSGNTLKLIRLRADCDRDTILATVEPTGPTCHTGNWTCFT DQRYTWELLQNIVTERFRNPKPGSYTATLDDERVREKVMEEAEEVCTAKTHDEIIWEV ADLLYFTTVLMTRAGVSVVEVMAELDRRHKK" gene 7652..8830 /gene="" /locus_tag="" /db_xref="2743405..2744583" CDS 7652..8830 /gene="" /product="Histidinol-phosphate aminotransferase" /translation="MTRLMKGSPYWSSRCAALEPYTPGEQPRDRRYIKLNTNESPYPP SPKVLEALKTAANGDLRLYPDPTCLALRETIARRYGLPGPEWVFVGNGSDEILAFAFA AFFGPRKRTGSTPASGSGLITGQSGPDPLYQDEAPLLFPDITYSFYPVYAQLWNIPYG TIPVSDTFEIDPREYLQRAAGVVLANPNAPTGRALGKGALRELAAFHQQNQRVVLIDE AYVDFGGESMAEDVKQFDNLLVVHTLSKSRSLAGLRVGYALGHPDLIEGLRRIKDSFN SYTLDRLALAGAQAAIEDRDYYDAMAARIIATRERTCTQLEALGFEVIPSGANFIFIR HPARRGAELFQSLRDRGILVRHWNKERISEYLRVSIGTDEEMDSFVGCCQELVEKPNT" gene 8859..10256 /gene="" /locus_tag="" /db_xref="2744612..2746009" CDS 8859..10256 /gene="" /product="Histidinol dehydrogenase" /translation="MTILKAKDFDAYWNSLHGGRPLPRGDAAAAGPAHLASSPAAAAP VAASPSPEALSPSAATATDTAVLAIIEAVRSGGDRALRDLAARFDRSSPERLEVPMTA ARRALEELEATDASLATALRLAADHIRVFAELQKKQFTDFEVKLEPGLFTGQRCIPVE RAAVYVPAGRFPLISTVLMGVIPAKVAGVDELIILSPPLEDGLPDRRILAAAALAGAD RIFAVGGAQAVAAAAFGTESVPRCDVIVGPGNKYVAAAKRLLFGQVGIDFVAGPTDVL IIADGTASADLIAADMLAQAEHDPDARARVLVPSEALAQAVQADLVRRLSKLGTADTA RASLDAGGLIIIYETLDEAIQIANTIAPEHLELHLAEPETIAGRLRNYGSLFIGHLAA EVLGDYSAGINHTLPTSGTARFTGGLSVRHFIKTVTSLRCTPGSGFETSRKAAAIIAR AEGLDGHRQSAESRG" gene complement(10472..11239) /gene="" /locus_tag="" /db_xref="2746225..2746992" CDS complement(10472..11239) /gene="" /product="hypothetical protein" /translation="MELIKYKNYQLFPGELLWVTGSLYFTWFILSNYNPIRFVNGVML LLLSIYSLGLSILLFIEIQKKVYRILNIFFSWFINVLDGILNYIILKGPYGSNSDGFI MWQKINPVYDVWFIIAIMIFKIGVSSIVIVCIERGFSAPLGSLQRMNFFELQAIPYKA IENNSAYRVVKSLFSKNSETLLLDIQVIHAYYKVFYQPLCLVIMLLVYVFFNNLSVYF IEPIGPLFISVYVMYGLIIGIIIMPVFLYIYYKKKAN" gene complement(11715..12044) /gene="" /locus_tag="" /db_xref="2747468..2747797" CDS complement(11715..12044) /gene="" /product="integrase catalytic subunit" /translation="LAPAYQSFYLVIGDVLQKLERSQEAATAYKKTLTMTPHILRPRG IGRWSRKIVGWEIHNRETTSLASQCFERMVARNGTRPVYLYVDNGNPMQEHAQQWFAD FVHWYIT" gene complement(12063..12449) /gene="" /locus_tag="" /db_xref="2747816..2748202" CDS complement(12063..12449) /gene="" /product="hypothetical protein" /translation="MSVEISELSGLLDSASKMVNDRLAHAPGWQVLQVIQTQLQAMQD DVNHERVPTAEAKKRINIGVLAVREFEANDPEFADILIKAAYLYKKLSPRLSTTVPVP QEQANALVAEANTLQATGGYEEAVKA" gene complement(12917..13291) /gene="" /locus_tag="" /db_xref="2748670..2749044" gene complement(13345..13545) /gene="" /locus_tag="" /db_xref="2749098..2749298" CDS complement(13345..13545) /gene="" /product="hypothetical protein" /translation="MHEVPWAREQSGFLQVYRVGVDETRQREQIEVKDLNKIIISWFK NPENLTIKTGYAYRLLTGSLVS" gene complement(13666..14694) /gene="" /locus_tag="" /db_xref="2749419..2750447" CDS complement(13666..14694) /gene="" /product="Cellulase" /translation="MKERTAWFGILGLMVMLISACGIDDTQLSVDKNGKTVVERFGQL QVIGTKLCTEGGKPIQLRGMSSFGLQWAGKYANEDVIGWLRDDWNIQVWRAAMYLTEG GYIQNPVIKEKVISSIEAALKLGVYVIVDWHVLSDKNPQAYQAKAIEFFTDIAQQYRK YPHIIYEICNEPNGKDVTWQGNIKPYAEAVIAAIRQYDPDNIIIVGTPNWSQDVDVAA ADPIQNQKNIMYTLHFYAGTHGQELRAKAEKALAKGLPLFVTEWGTSDASGGGGFYME KSKEWLSFLKKHKISWVNWSVNNKGEESGALVYNADREGKGYWKDSDLSESGRFVRKV LRNEIRIP" gene 14922..15863 /gene="" /locus_tag="" /db_xref="2750675..2751616" CDS 14922..15863 /gene="" /product="hypothetical protein" /translation="MSSSISSVKDHRLDREAGAIIYPVISRRAGGLSVGINLFPDRKT CSFDCPYCEVFPFEMDLKFSLAAMEQGLRNLAEELQTDPPAHPVRDISFSGNGEPTLH PDLIPALTLAARLRRELFQVHQPDVKLVLITNGTGLLDTSIAAFLAQAARGEMPYFDG PSEALEIWLKIDAGTKFWYEQMNRSALPFEALNEAIDAFARRAPFIIQTMICKVDGQL PPEEEVTAWEGRIRQLVEASLIEAPPHPPLADESSAPTGGKHRTVGPQAIQLYGKARP APEDPKTEPVDESYLAARRASLLKALALHHLPINLFV" gene 16025..16792 /gene="" /locus_tag="" /db_xref="2751778..2752545" CDS 16025..16792 /gene="" /product="hypothetical protein" /translation="MKKCSIAIAFLYVLLFVSCATNSTTAKDDSTIDSVAVVTKKNFE LDMYADAPQSVRDAIARCDSLITQAKYASALRALSIDEDLGKDKDYIIYKWTEVITNW FSFSMMHTMFDIKDFNSEEELYAYRRDISYGNKEMSFNLTVDYTGPEGKIDEYEKIYG ETPRTNLARAQYYFDVSQRYKDQWLKPYDELLSLAYENYRKAISANFYNLRALENYAQ SALLTNHFEEAYKGYKDLVEYRPEFGNYWYNFAVSSM" gene complement(16855..18318) /gene="" /locus_tag="" /db_xref="2752608..2754071" CDS complement(16855..18318) /gene="" /product="transposase, IS5 family" /translation="MYKEKEQVPEFEDFYVPFGGHLREDNRWVRLAAIIPWEEIEAEY KKCFSKRIGRTAKTVRLALGSLLIKEKLQLTDEETVETIRENHYLQYFLGYESYKDEK PFDPSMMVHFRKRLGPDAIAQINELIAKRYQEQVEAESEKKQNKENQKDDHDHGNRGQ LIIDATCVPQDIRHPHDVTLLDEARRKTEKIIDTLYEASELTIKPRTYRKQARIKYLN FIRGRRRTKKEIRRAIRTQLQYIRRNLRTINELQNKVPSTTLSAKQRRDLIVIHEVYR QQVQMYKGKTHSISGKIVSISQPHVRPIARGKAKAAFEFGAKLSASMTEHGMIFIDRL QWEPYNEQEDLPTQIEKYKRRCGRYPESVHADKIYRTRANRAYCEARGIRLSGPPLGR PIKETLENKKIVRQLRKIQRLDEAIRQAIEGGFGYMKRKFGLGTIYEKLRETSETAIM VCVLLTNCEKILRDLFMRFLFLLGFKPHKSYLKVLVY" ORIGIN 1 atgaaatcac agaacttaat aaaactagta aaaccagtca ttatcgtttt ttatcttctt 61 ttcgtatgtt taatctttgc agaaacaact acaaccatta cagacattga agtacaaggg 121 ctgaaacgaa ccaacccaat agtggtaaaa aatctgttaa aggcctatat caatagagat 181 gcagataaaa tcaacactga tgaaattatt gcacttctcg ttgctacagg tatttttgaa 241 aatgttactg tttctgttaa agaaaacacc aaccaaacag tattgttcat cagtttggaa 301 gaaaaatggt ccatcattcc attaccactt gtttctataa aatcagatag ttatgtattt 361 ggattaggtt tctttgatgc taacgccttt ggccttaatc ataaactctt ttcttccgca 421 agtgtatcat caaagggacc atcgattgcc ctaggatata ttattaactc tttatggcaa 481 agcaaatggg acggtgtatt ttctatttcc tatgcaacaa aagatgagac cttcactgat 541 gtctatgagc atgaaattag tacatccgat attacctcat tttccgcaac aataagcgga 601 aactattcta ttttgaatat attgaaatgg gattttggtt ttgaatatca aactaaatca 661 tatactgatg aacaagatac agatctcact agcctaggac tacaaacagg cataacttta 721 caatcaaatg ctcattggaa tggtgtattt cttacaatgt ctggagtcca gttctattac 781 acctggtatt atggcataga agggccatcc tatggggtat ttttaacaaa gggatcctac 841 gaaacggcac cagtaaaaaa ccttaaactt tcatttagaa gtgttggatt gtggggcccc 901 caaacaccac aactagcaga aataggagct aacaaacttg gcttaatcat acttcctgat 961 acctatactg tttatactat ggcaaccttt agatccggtc ttgaactaaa acttttttca 1021 tctggaatag taacctttgc aggtttagca cattatcata taggttattc agagggctct 1081 cgaacagagc cccatattga ttatggacca tcctttggtt tacgactcta tcttgcaaag 1141 gtagctttac ctgccatgga cataaatatc gcttataacc agactaccgg cctttaccag 1201 gccagttttt ctattggaat gcaaatgtaa atacacctgt ccaaagggca atagcctttt 1261 ggacaggtgt tcctttattt tttcattata tacgcaacag cgttttcacc agcaatccga 1321 ccaaaggtaa ctatatcagc gagcgcattt cctcccaaac ggtttccacc atgaactcca 1381 ccggtaacct caccagcggc atataatcct ggaataacag aaccgtctgt gcgaagcact 1441 tgagctgagg tattaatctt taccccgccc atggtatggt gaatcgcagg agttaccttt 1501 atagcataat agggagcttc cgataacgtt ctcggcatat cactgcgacc atattcagta 1561 tcctttttag aaagaacagc atcattatag ttttttatgg tcttctcgag ggtttcagaa 1621 gtactaccaa ttttatgggc caaatcagca agattttgag cttctaaaac aaaaccggct 1681 tttaaatagc tttcaattgc agataaactt tttcgtaccg aattatcaaa tacaagatag 1741 gctattttcc cttcctgggc aagtattttt gcagaaacca catcccgagt ttccaattca 1801 tcaacgaaac gcttgccagc tgaatttacc aaaatagcac cattaccccg tacggcctca 1861 gtaaccatct cattgccatc gggtgcaaag gtgggatggg tctgaatctg atccatatct 1921 actaatgctg ccccaatagc ttgggccatt aggataccat cccccgttgc accagcatga 1981 tttgtagtag caaatccttt taatgcaggg ttaaattttg cagccatttc attattagcc 2041 ccaaaaccac cagatgcaag cacaactgct tttgctgtca ctttatagtc ttttccatca 2101 atacgaacta ctactcctgt aacagcccct tgtttattgg taagcaatga tcttacttcg 2161 gcatcagtaa agatggagag cgtagcagat tgtttggcct tattggcaag ggttttaaca 2221 atttctggtc ccactttagc accaccagaa ggccgatgag cccgattaac actggcaccg 2281 gctaagcgcc ccacatctga taaatccgca cccatatcag taagccatga aactgatgct 2341 gcacttttcg ttgccagagt tttaactaat tcaggatcat tcttgttgta tccgcccttc 2401 atagtatcct gaaagaaaag atcaggacta tctttaattc ccttttcggc ttgtatagca 2461 gtacctgctg catttatacc accagtagca cgaatggtat tgccacccag gatccccatt 2521 ttttcaaaaa gaacaacccg tacccccttt gcaacagcgg catttgctgc agaaagtccc 2581 gcaccaccac caccaataat gacgagatca taggactttg caggcagatt tttacttctt 2641 ccctgtgttt ttgttttttt aacggcaacg aaacctgcct tattcaaagc atcttgaacg 2701 gctgatatat atccattact tgcttcagtt gcaccactta ctacatcaac ctcggtacta 2761 tttgccttta ggattcggtc tttcaaagtt gcaaaagcag tatcaccaag gaatgctgtc 2821 tcctgcatac tcattatttt aatgtctttt atatctgttt cagtaaccgt aactagtacc 2881 cttatgtctc caccatgacc ttttccttca ccttcatagg taccaggctg gaaacgaggg 2941 gcggtgctga cacagccgat gaatgctaca ctagcccata aaatgatagt gtgcaaaaaa 3001 tatttaatcc tcataaaacc tccaattgca ttatgggtat attattatag atataatatt 3061 attgagtcaa ccagttatac cataacatcg attaacatca tttaagcggc tctctaagag 3121 gcattgaaat tgggtagctg ctttaattct gtatatttat tcatcttcgc ccccccccac 3181 ttgacatatt ttttgcatac cggtagtata tttatatgaa acggattact atgaaccacc 3241 atcatcatca tgggtactca tccagggggg catagggtcc ggtgccgcgt tgcggttctg 3301 ttcggcatat acagccgtgg gctctatggg gtccacggct ttttttatgc cccgaagggg 3361 acgtttaaaa ctaaggttat aaaactttag tttataaagg caccccgaag ttacaaggag 3421 tttttgtatg ggaaaattgc ggattttaat acccaagggc aggatatttg acaatgtgtc 3481 ccgattgttt gccgaagcgg gtattccaat aagcctttcc gagcggacct accggcccaa 3541 cattgccgct gactggctcg atggaaaggt catgaaaccc cagaatgtgg gggaactctt 3601 agaaattggg agccacgatg caggttttac cggcatcgac tggatccgtg aaaccggatc 3661 gaacgtggta gaagtgatgg acctgggctt tgaccgggtt cggattgtgg cagcggtccc 3721 cgctgaaatg gacgaggctg ccctgcgggg aaagaaactt gttgtagcca ccgagtatgt 3781 taaccttgcc cgggaatggc ttacgaaaaa gggctatgat ttccggattc tcaggaccta 3841 cggcgccacc gaagtattcc cgccggatga tgcggacatg atcgtcgata acacctccac 3901 cggccaaacc ctgcgggaca acggcctgcg gatcgtagat accatccttg agtcatcaac 3961 ccgttttgtt gcatccaaga ttgccatggc agatccggag aagaaggctc agattgatga 4021 actggccatg ctctttaagg cggtccttga tggccgcgaa aaggtcatgc tcgaaatgaa 4081 cgtgaataag atccgcttcc ccgacctggt ggcagggctt ccggctatgc ggagccccac 4141 catcgcccct ctgtatggtg atgacggcta tgcggttaag gttgccgttc cccgccacga 4201 ggtgcccatc ctgattcccc agcttaaacg gcttggagct accgatattg ttgaatatga 4261 gctgcgtaag gtagttccct gatacgaact caccctcagc cggcggcaga tcgacaaaga 4321 ttacaaggat gcggccgcgg aggcccgcaa aggaggagcc atggaacgga ttgcggaaat 4381 tacacggaaa accggagaaa ccgatataca ggtaaaactc aatattgatg gaacagggtc 4441 ggccaaaatc gactgccccg taggttttgt aacccatatg ctcaccacct ttgcccggca 4501 tggccttttt gacatagagc tcactgcccg tggagacctg gaggtggatc agcaccacct 4561 ggtagaagat ataggcattg tactcggtca ggcttttgcc aaagccttgg gggacaaagg 4621 gggcatcaac cgggtcggaa gctgtctctt ccctatggat gaaaccctgg cccgggcagc 4681 ggtggacctg tccggcaggc cgtacctcgt attcgaggcc aatctgagcg gcctccccct 4741 ggtttccacc gaggccagtt ttcagaccga tacggtagaa gacttctggc tcggttttgc 4801 caccaatgcg gcctgcgcgc ttcacctgga tatactccgc ggtcgcagtg accaccacaa 4861 gattgaagcc ctctttaagg ccgctgcccg ggccatgcgg gaagcctgca gtatcgataa 4921 ccgcagtttg ggccagatcc catccaccaa gggggttctg gcgtgattgg cgtcctcaac 4981 tacggggcag ggaacctggg atcggtgatg aatgcccttg cccggctggg ccttccggcc 5041 caattcgtga caggtccgga ggaactgcag gttcgccggg gaaacaacag cggatcttcc 5101 gccggccagc agtactcggc catcattttt cccggggatg ggcacttcgc caccgccatg 5161 gaagccctca cagcccaggg ctataccgaa gccatccggg agtggattgc tgcggacctg 5221 ccctttctcg gcatctgtat cggcctgcaa ttactctttg aacagagcga agaagcaccg 5281 ccggttcagg gcaaggaaat ccctggatta tcggtaatac cgggaagggt gaaaaaattc 5341 cagggaccca aggttcccca gattggctgg aatgaaacca aaggtacaag ccgttcacgg 5401 cttttccaga acctgccgga acgttctttc ttctattata tacattccta ttatgttgta 5461 cctgcagagg aagactgggt tgccgcagag gcagactact atggaaccta ctgcagtgcg 5521 gtggaacggg gtgccctgac ggcggtccag ttccacccgg aaaaatcggg agctctggga 5581 ctggaactcc tgcggcgctg ggctgaggtg taccatgtta gctaaacgaa tcattccctg 5641 cctggacgta gatgacggca gagtcgttaa gggaataaag tttgaaggca ttaaggacgc 5701 gggggacccg gtggaactgg cccgctgcta taatgaacag ggagccgatg agctcacctt 5761 tcttgacatc ggcgcctcct acaaaagccg ggataccctc atggaggtag tccgccaggt 5821 tgcccgggaa gtctttatcc ccctctgcgt aggagggggg atccgcacgg tagaggatat 5881 gcgccttgcc atgaacgctg gggcagacaa ggtatcggtc tgtacggcag ccctgcggaa 5941 tcctgcactg ctcaccgaga tggcccgggc ctatgggagc cagtgcgtgg tcctttccat 6001 cgatgcaaaa cgggtatctg agcccggcga agctccccgc tggcatgcct ttgccaaggg 6061 cggcagggaa gatacgggga ttgatgccat ccagtgggcc atagaggcgg tccggctcgg 6121 agcgggggaa atactcctta actccatcga tgcggacgga accggtgcgg gctatgacct 6181 tgaactaacc cgccgggtgg gagaagcggt tcccgtgccg gtgattgcct caggcggggc 6241 gggtaatctg gaccagattg tccaggctct tatcccggaa gggggcaacg ccgatgcggc 6301 cctggtggcc agcatgctgc acttcggaaa aacaacgata caggaaatta aaacctacgc 6361 agaacagaaa ggagtggtag ttcgatggta atagcttcta tagatattca aaacggaaaa 6421 gtcgtccagc tgaaacaggg ttctcagctc atgctcgaac gggaagatgc ggcagaactg 6481 gccgccgaat tcgacaaata tggggaagtg gcggtcatcg acctggatgc ggctatgaaa 6541 accggttcca acgacgaatt ggtcaaatcc ttgctccgcc gggccgattg ccgggttggc 6601 ggcggcatcg ccacagtgga acgggcggcg gagctcgtca gcctcggggc aaaaaaggtc 6661 ataatcgggt ccaaggcttt ccggacatca ggagacagtt tcggcattaa cacagccttc 6721 ctggaagccc tggcaaaaaa gatcggccgg gagcgggtta tcgtggccgt cgatgcccgg 6781 gacggcgaaa tcgtcgtcga tggctggaag acccccacag ggctgcccct tatcgagagt 6841 gccaaagcgc tggaacccta tgtgggggaa ctgctttaca cctgcgttga gcgggaagga 6901 accatgaccg gcaccaacct ggacagtatc cgctccctgc gggaagcggt ttcctgtctc 6961 gtcacggttg ccggcggcgt gagcaccctg gaagaaatcg aagccatcgc ccggctgggc 7021 tgtgatgtcc agctcggcat ggccctctat accggcaaaa tcaacctggc cgatgccttt 7081 attgcaagcc tttcctggaa ccaggcctgg caggagggaa aactgctacc cgtcgtcgcc 7141 caggccccgg acggtcaggt tctcatgctg ggctacaccg acagggaggc cctggcggag 7201 acctttaagc ggggaaacct ctgctttcac agccggagcc gcaacaagct ctggatgaag 7261 ggtgaaagct caggtaacac cctcaaactc attcggctcc gggcggactg cgaccgggac 7321 accatacttg cgacagtaga accgacgggt cccacctgtc ataccggaaa ctggacctgt 7381 tttacggacc agcgctatac ctgggaactt ttgcagaaca tcgtcactga acggttccgc 7441 aaccccaaac cgggttccta cacggcaacg ttggacgatg aacgggtccg ggaaaaggtg 7501 atggaagaag ccgaagaggt ctgcaccgca aaaacccatg atgaaatcat ctgggaagtg 7561 gcggaccttt tatattttac gacagtattg atgacccggg ccggagtctc ggtggtagag 7621 gtcatggctg aacttgatcg gcggcacaag aaatgaccag gttgatgaag ggaagtccct 7681 actggagcag ccgctgtgca gctctggagc cctacactcc gggggagcag ccccgggacc 7741 ggcggtacat caaactgaat accaatgaaa gcccctaccc gccttcgccg aaggtgctag 7801 aagcgcttaa gactgcggcc aacggggacc tgcggctcta tccggacccg acatgccttg 7861 cgctccgcga aacaatcgcg aggaggtacg ggcttccggg ccccgaatgg gtctttgtgg 7921 ggaacggctc tgatgaaatc ctcgcctttg cctttgcggc ctttttcggt ccccggaaac 7981 ggaccggctc caccccggca tccggctcag ggcttatcac aggacaaagc gggccggatc 8041 cgctctacca agatgaggct cccctgctct tcccggacat cacctacagc ttttatccgg 8101 tctatgccca gttgtggaat attccctacg ggacgattcc ggtttcagac acgtttgaaa 8161 tagatcctcg ggagtacttg caaagggctg ccggtgtagt cctggcgaat cctaacgcac 8221 caacaggccg cgccctcggc aagggggctc tcagggaact ggccgccttt catcaacaga 8281 accaacgggt agttttaatt gatgaggcct atgtggactt tgggggcgaa tccatggcgg 8341 aagatgttaa acagtttgat aatctcctcg tggtccatac actttccaag tcccgttctc 8401 tggcagggct cagggtgggc tatgcactgg gacatccgga ccttatcgaa ggcttgcggc 8461 ggattaagga ctcctttaat tcgtatacac tggaccggct tgcattggca ggtgcccagg 8521 cggccatcga agaccgggac tattacgatg ccatggctgc tcggattatc gcaacccgag 8581 agcggacctg cacccagctc gaagccctgg gattcgaagt aattccctct ggggcaaact 8641 ttatctttat ccggcatccg gcgcggcgcg gggcagaact gtttcagtcg ctgcgagacc 8701 gtgggatcct tgtccgtcac tggaacaagg agcggatcag cgagtacctc cgggtgagta 8761 tcgggaccga tgaggaaatg gacagctttg taggctgttg ccaggaactt gtagaaaagc 8821 caaatacgta gggagcgcca tcgcaccaga ggaatgatca tgaccatact gaaagccaag 8881 gattttgatg catactggaa ctcactccat gggggcagac ctttgccccg gggagacgcc 8941 gcggcggctg gccccgcaca cctcgcatcc agccctgctg ccgcggcccc tgttgccgcg 9001 agcccctcgc ctgaggccct aagcccatca gcggccacag cgaccgacac agcggtcctc 9061 gccatcatcg aagctgtccg ttccggcggg gaccgggccc tgcgggacct ggcggcccgc 9121 tttgaccgct caagcccaga acggctggaa gttcccatga ctgcggcccg ccgggccctt 9181 gaggaactgg aagcgaccga tgcgagcctc gccacagccc tgaggctcgc cgctgaccac 9241 atcagggttt ttgcagaact gcagaaaaag cagtttaccg actttgaggt gaaacttgag 9301 ccggggcttt tcacgggtca gcggtgcatt ccggtggaac gggctgcggt ctatgtcccg 9361 gcgggccgct tccccctcat ttctacggtg ctcatggggg tcatccccgc aaaggtagcc 9421 ggtgtggatg agcttatcat cctgtcaccg cctcttgaag atggccttcc ggaccggcgc 9481 atcctggccg cagcggcatt ggccggggca gaccggatat ttgccgtcgg cggtgcccag 9541 gctgttgcgg cagccgcctt tggaaccgaa tcggtccccc gctgtgatgt gatcgtgggg 9601 ccgggaaata aatatgtggc cgccgcaaag cggctcctct ttggccaggt cggcatagac 9661 tttgtggcgg gtcccacgga tgtgctcatc atagccgatg gaacggccag cgcggacctc 9721 atcgccgcgg atatgctggc tcaggcagaa catgatccgg acgcccgcgc ccgggtccta 9781 gtccccagcg aagcgctggc ccaggccgtg caggccgacc tggtgcggcg gctgagcaag 9841 ctgggcaccg ccgacaccgc ccgggcatcc ctcgatgccg gggggcttat catcatctat 9901 gaaaccctgg acgaagccat acagattgct aacaccattg caccggaaca cctggaactg 9961 cacctggcag agccggagac cattgccggc aggctcagga attatggctc cctctttata 10021 gggcacctgg cggcggaagt gctgggcgat tattcagcag ggattaacca tacccttcca 10081 acttcaggaa cagcccgctt taccggcggc ctctcggtcc ggcacttcat taaaaccgtc 10141 accagcctcc gctgtacgcc aggttccggc tttgagacaa gccgaaaggc cgctgccata 10201 atcgcccgtg ctgaagggct cgacggccac cggcaaagcg ctgagagcag gggatagtct 10261 gcaagatcag gtttcacacg taggatgaga tctgtttagg aaacgtggcg catctcaaaa 10321 gctaaccgag cttttagagg cgcctattat tcaaccttaa agttccgaac ctggttgata 10381 atatgctgaa actgctcaaa aaattattgg ttcaatgaac tgatattcac cgtatactct 10441 ttaacgctgc tggtacggaa tgtatcgtat gcttaatttg ctttcttttt ataataaatg 10501 tataaaaaga caggcataat tatgatacca attattaaac catacattac gtagacagaa 10561 ataaataaag gtcctatagg ttctatgaaa taaacactta aattattaaa aaacacataa 10621 acgagtaaca taatcaccaa acataagggt tgataaaaaa ctttatagta tgcatgaata 10681 acttgaatat ctaatagcaa ggtttcgcta tttttagaaa atagagattt tactactcta 10741 tatgcagaat tattctctat tgccttatag ggtatcgcct gaagttcaaa aaaattcatt 10801 ctttgtaaac tgcccaatgg tgcgctaaat ccccgttcaa tacaaacaat aacaatacta 10861 gaaacaccaa ttttaaatat cattattgct atgatgaacc atacatcata tacagggttt 10921 attttttgcc acatgatgaa gccatcacta ttagaaccat atggaccttt taaaattata 10981 taatttaaaa ttccatctag tacatttata aaccaagaga aaaatatatt taaaatacgg 11041 tatacttttt tttgtatttc aatgaataaa agtatagata atccaagact ataaattgat 11101 aataaaagca gcattactcc gttgacaaat cggataggat tataattgga taaaataaac 11161 caagtaaaat aaagtgatcc tgttacccac aaaagttcgc ctggaaaaag ctgataattc 11221 ttatatttta ttaattccat ggtaaaccaa cctattattt ggccgctcaa accattaact 11281 catttgagta gcatgtgttt ttagaattta ctacattgct gaacagctct tcctaaatca 11341 tatgaatcac atgcatattg cactgcttta ggaacagaag gatttttaat tgcatataaa 11401 ccaacacctg ctgcaacaac atctgcaaca accactgctg tttttttaat ttcatttatt 11461 gaatttttta cttgagattt ttatgtacgg gaacctgaac ctctgccatc accatggtag 11521 caccacgtta tttgtcaaca tagatgtcgc ccgtttaatg atgctgtgcg ttcagcacca 11581 ctctgtcaca atggacccaa tctttaaggg atgaccgtat ttctggtcga aagagccgta 11641 cataggtaag agctctttat caataccata gtggcgctga tcgggtgtca cagagccaat 11701 cccagcatgt cgatgttaag taatgtacca atggacaaaa tcggcaaacc actgttgtgc 11761 atgctcttgc ataggattcc cattatcaac atacaggtaa acaggtcgtg ttccattccg 11821 tgcaaccatt ctttcaaaac actggctcgc taatgatgtt gtctcccggt tatgaatctc 11881 ccagccgaca atctttctac tccagcgccc aattccccta ggcctgagaa tatgtggggt 11941 cattgtcaat gtttttttat aggccgtagc ggcctcttga gagcgttcca gcttttgcaa 12001 tacatcgcca atgaccaggt aaaaagactg ataggcagga gccaacaaaa tggcctccta 12061 atattaagct ttgacagctt cctcgtaccc gccagtggcc tggagggtat ttgcttctgc 12121 tacaagggca ttggcttgct cttgcggcac cggaacagtg gtagatagcc ggggtgagag 12181 tttcttgtag aggtatgccg ccttgatcaa aatatcagca aactcgggat catttgcttc 12241 aaattctcga acagccagaa cgccgatatt aatgcgcttt ttcgcttccg cggtcggtac 12301 acgctcatga ttaacatcat cttgcatggc ttgcaactgg gtttgaatca cttgcagcac 12361 ctgccagccc ggcgcgtggg ccaacctgtc attgaccatc ttacttgctg agtctagcaa 12421 tccgctcaat tcggatattt ccacactcat atcattcccc taaggtatga aaactaccct 12481 tgtcagcaga aaagaactgg acacctccac caatacaaga aaaattgata ggaattgtca 12541 tttcgtggtt tttacggttt tgcgtcgaaa ttcggttttt cccctaaaat tattttccag 12601 cccgaacaac taaaccaatc aaaaatttcg gcaacgccaa cactgtgaag tataatttca 12661 gtctatttct gccgtcaatc cctgattcga gccaatgtga caaagctcaa aaatataact 12721 ccccctcaaa gccatataac ctccggtttt gagtttttat cctgttccgc ataaacttca 12781 ttttgggagt ggaacctagg gaattctcca aaggattggt tactgacaac acagacgcac 12841 agcagtggcc gccttgcagc aagggagaaa aattcagaca gtagcgagaa tagtaacttg 12901 gatacctctt caaacaagcg tttatcagat ttaaagtatg gctttagatt cttgggaatc 12961 gtaaacacaa attgccaatg cgataaatcc aacagcaagt cctaagccag gtattcagca 13021 tagagtaagg tcctcttttg gttgcaggat ggacaaagat tgaaaacctt gcacgaaaac 13081 ggcctgaagt aggaatgacc acaatcttcg taacggatac gagctacacc ttttgaccag 13141 tcggcgaaac cagtgaattg ctctaggcgg tcaagaattg tctggggtgg actggcatag 13201 gcttggtact gagtaagaga attgcggact atggtctgga ttactccttc ccgatgggga 13261 ataagtgtat atgcagtctg caccaaacac atagagacag ttacaaaaca atatgactct 13321 tcactatttt atatggataa gcatctcagc ttaccagcga cccggtaagt aatctgtaag 13381 catatccggt cttaatagtc aggttctcag gatttttaaa ccaagatata attattttgt 13441 ttaaatcttt tacttcaatc tgttctctct gacgagtttc atcaacacca actcgataga 13501 cctggagaaa accggattgt tcacgagccc agggaacttc atgcatacag gtatattttg 13561 tattgaaaac aatcaaggta aatatccaat tttttaggcc aagaatcgcc tgaaatattt 13621 ttgcctaccc acacgtttga gcgaagagcc ctaaaattgt aaaaatttat gggatccgaa 13681 tttcgttcct taacaccttc cgaacaaaac ggcccgattc ggaaaggtcc gaatctttcc 13741 aatagccctt tccttcccgg tcagcgttgt acaccagggc gcctgattct tctcccttgt 13801 tattgaccga ccagttaacc caggaaatct tatgcttttt caggaatgaa agccactctt 13861 tggatttttc catataaaag ccgccgcccc cggaagcatc ggaggtgccc cattcggtta 13921 caaaaagagg aagtccctta gccagcgctt tctcagcttt ggctcgcagt tcttgtccat 13981 gggtccccgc gtagaaatgg agggtataca tgatattttt ctgattctgt atggggtccg 14041 ctgcagccac atccacatcc tgactccaat tgggggtccc cacaatgatg atattatccg 14101 gatcatactg gcgaattgcc gcaattactg cttccgcata gggctttata ttgccctgcc 14161 aggtcacatc cttaccgttg ggctcattgc agatttcata gataatatga gggtactttc 14221 tatattgctg tgctatatct gtaaaaaact cgatagcctt tgcctgatac gcctggggat 14281 ttttatcact gagaacatgc cagtccacaa tcacataaac accgagcttt aaagctgctt 14341 ctatggaact gatgaccttt tctttgatga cagggttctg gatataacct ccctcggtaa 14401 gatacatggc cgcccgccat acctggatat tccagtcatc ccggagccat cctatgacat 14461 cctcattggc atacttgcca gcccactgga gaccaaaact actcattccc cgaagctgta 14521 tcggtttacc cccttcggtg catagcttgg taccaattac ctgcaattgg ccgaagcgtt 14581 ccactacggt cttgccattt ttatccaccg aaagctgagt atcatcaatc ccacaggctg 14641 atatcaacat gaccatcaaa ccaaggattc caaaccatgc agtgcgttct ttcatcatcc 14701 tacttccccc attatcgtta taggggacct ctaaaacttc actttttaga ggcgctctat 14761 aatgataagg tcacatttat tgaatatttt caaacaatgc acattagttt aatctacttt 14821 aggagaaagt caagctaaga atcggtcatg agctattcaa gatgcactaa atagacaagc 14881 gaggctcgac cttggtcgaa ctctttttct ataataccag atatgagtag ctcaatcagt 14941 tccgtaaaag atcatcggct tgaccgggaa gcaggggcca ttatatatcc tgtcatatcc 15001 cgcagagccg ggggcctttc ggtgggcatt aacctgtttc cagaccggaa aacctgcagt 15061 tttgactgcc cctactgcga ggtgtttccc ttcgagatgg acctaaagtt ttctcttgca 15121 gccatggaac agggactgcg gaacctggca gaagagctcc agacagatcc ccctgcgcat 15181 ccggttcggg acatctcgtt ttccgggaat ggggaaccga ccctgcatcc tgaccttatt 15241 ccggccctta ccctagccgc ccggttgcgt cgcgaactct ttcaggttca tcaacctgat 15301 gtaaaactgg tgctcatcac gaacggcacg gggctcctgg atacatcgat agcagcattc 15361 ctcgcccagg cagcccgggg tgaaatgcct tattttgatg gcccctctga agccctcgag 15421 atatggctca agattgatgc gggaaccaaa ttctggtatg aacaaatgaa ccgttcagca 15481 ctaccctttg aggcactgaa cgaagcaatc gatgcctttg cccggcgggc ccccttcatc 15541 atccagacta tgatctgcaa ggttgatgga cagctcccgc ccgaggaaga ggttactgcc 15601 tgggaagggc ggatacgaca gttggtggaa gcctcgctta tagaagcacc accccaccca 15661 cccttggcag acgaatcatc tgcacccaca ggtggtaagc acagaacggt tggacctcag 15721 gctatccagc tctatggaaa ggctcgccct gctccggagg acccgaaaac ggaacccgta 15781 gacgagtcct accttgcggc tcggcgggct tccttactga aagccctcgc tctccatcat 15841 cttccgataa atttgtttgt atagggttat ctggccgcct catattactc tttttcctcc 15901 caaaaagcac atcacggcaa tactgcagaa gtaaaaaaat gagtatcatg ataaaaaaga 15961 aaacttgacc gattaaattg tctgtactat gctaactaaa tcaactttgt tataaggggt 16021 ttaatatgaa aaaatgtagt atagcgattg cattccttta tgttctactg tttgtttcct 16081 gtgcgaccaa tagcactact gctaaggatg atagtacgat tgattctgta gcggtcgtta 16141 ccaagaaaaa ctttgaactg gatatgtatg ctgatgcccc acaaagtgtt cgcgatgcca 16201 tagcccgttg tgatagcctt attacacaag ctaaatatgc atctgccctt cgtgctcttt 16261 ctatagatga agatctggga aaagataagg actatattat ctataagtgg acagaagtaa 16321 ttaccaactg gttcagtttt agcatgatgc atactatgtt tgatatcaag gactttaata 16381 gtgaagaaga actgtatgcc tatcgccgcg acatttcata tggcaacaaa gaaatgagtt 16441 ttaatttaac cgttgactat accggacccg aaggtaaaat tgatgaatac gaaaaaatct 16501 atggcgaaac tccaagaact aatctggcac gggctcagta ctattttgac gtctcgcaac 16561 gctataaaga tcaatggtta aaaccatatg atgaactact atcacttgca tatgaaaatt 16621 accgcaaagc tattagcgcg aacttttaca atctgagggc ccttgaaaat tatgcccaat 16681 ctgctttatt aactaatcat tttgaggaag cttacaaagg gtataaagat cttgtagaat 16741 ataggccaga gtttggcaac tactggtata atttcgccgt atccagtatg tagggcctac 16801 tgaaaatgtc taaaaatgat atttcaaaac ttttttacgt taaaatgggt ttaatttagt 16861 atactaaaac tttcaaatat gatttatgag gtttaaaacc aagtaaaaat aaaaagcgca 16921 taaaaagatc cctcaggatc ttttcacagt tggtcagcaa tacacatacc atgattgctg 16981 tttcactagt ttcgcgtaat ttttcataga ttgtaccaag accaaacttt cgtttcatat 17041 atccaaagcc accttcaatc gcttgtcgaa tggcttcgtc aagtctttga atctttcgta 17101 gctgtcgtac tatcttttta ttctctaatg tttctttaat cggtctgcct aagggtggtc 17161 cagacaatcg tattcctcga gcttcacaat aggctcggtt tgctcgtgtc cgatatattt 17221 tatcggcatg caccgattcc ggatatcgac cacatcgcct cttatatttt tctatttgtg 17281 ttggcaaatc ttcttgttcg ttatagggtt cccattgtaa tcgatctata aaaatcatcc 17341 cgtgttcggt catcgatgct gatagttttg ctccgaattc aaaggccgct tttgctttac 17401 ctcgggctat tggtcgtaca tggggttgac tgatactgac gatttttccc gatatcgaat 17461 gggtctttcc cttatacatc tgtacctgtt gccggtaaac ctcatgtatc acgataagat 17521 cacgtcgctg ttttgcactc aacgttgtac tgggaacctt gttttgtaat tcattgatag 17581 tccgtaaatt acgtcgtatg tattggagtt gggtccgaat cgctctgcgt atttcttttt 17641 ttgttcttcg tcgccctcgt ataaaattga gatatttgat acgggcctgt tttctatagg 17701 ttcgtggttt tatggtgagc tcactcgctt catataacgt atcaattatc ttttctgttt 17761 tccttcgcgc ttcatccaat aaagtgacat catggggatg ccggatatcc tgggggacgc 17821 acgtggcatc tataatgagt tgccctcgat ttccatgatc atggtcatcc ttttggtttt 17881 ctttgttctg ttttttttca gattctgctt ctacctgttc ttgataccgt ttcgctatca 17941 actcatttat ctgtgctatt gcatcaggtc caagccgttt tcgaaaatga accatcatgc 18001 ttggatcaaa gggtttttca tctttgtaag attcatatcc taaaaaatat tgcaggtaat 18061 ggttctctcg tattgtttct accgtttctt catctgttaa ttgtaatttc tcttttatca 18121 ataatgatcc caaggcgagc cgtacggtct tggctgttct tccaattcgt tttgaaaaac 18181 attttttata ttcagcttct atctcttccc atggaataat tgcggctaat cgtacccatc 18241 gattatcttc tcgtaaatgt cctccgaagg gtacataaaa gtcttcaaac tcaggtacct 18301 gttccttttc cttatacatc gttaccccat agtaaagtgc acgcttt //