LOCUS NC_014253:13 23447 bp DNA linear BCT 09-OCT-2011 DEFINITION Methanohalobium evestigatum Z-7303 chromosome, complete genome. ACCESSION NC_014253 SOURCE Methanohalobium evestigatum Z-7303 chromosome, complete genome. COMMENT locus start: 2113233; locus end: 2136679 FEATURES Location/Qualifiers source 1..23447 /organism="Methanohalobium evestigatum Z-7303 chromosome, complete genome." gene complement(0..1280) /gene="" /locus_tag="" /db_xref="2113233..2114513" CDS complement(0..1280) /gene="" /product="thiamine biosynthesis protein ThiC" /translation="MTLLEDAVNGKITDEMKVVAQKEGLDPEYIRRGIANGRIVIPTS PYRDVKLCGIGEGLSTKVNASIGSSSDISNIGLEVEKAKAAEEAGADTLMELGTGGDF LEVRKEVVDNTSLSVGSVPLYQAFIEAAQKRGSITDMTEDDLFKATEEQAKLGTNFMA IHTGVNNITLDRLKKHGRYGGLCSRGGAFMSTWMLYNEKENPLYSEFDYLLEILKEHE VVLSMGNGMRAGAVHDATDRAQIQELIINTELAEQAQNEGVQVIVEGPGHVPMDEIET NVKLMKSMSGNRPFYMLGPLVTDVAPGQDHIVTSIGASASSAAGCDFLCYVTPAEHLA LPNVDDVREGVKASKIAAHVGDMVKLGKRDNDLDMARARCNLDWEKMYSLAIDSQTAR TIRNDRAPEDEDACTMCGDFCALKIVNQHYDLAK" gene 2014..2343 /gene="" /locus_tag="" /db_xref="2115247..2115576" CDS 2014..2343 /gene="" /product="hypothetical protein" /translation="MRIWDIPPDKLCRNHLLGEHRELHALWSIIINNKKAYSNHPETL RWKDKLRALHLRHEKLVEEMDKRGYNHQSPLDVRFATGSDTQDEFIDSYEKQVKILKE KNCGCSV" gene complement(2352..3278) /gene="" /locus_tag="" /db_xref="2115585..2116511" CDS complement(2352..3278) /gene="" /product="glycosyl transferase family 2" /translation="MNVSTPENENVCILIPTLNEESTIVEIIRGFKSEGFDNIFVIDG NSTDRTCELAEGEGASIVVQSGKGKGQAVQEAFNIIESEYVVMVDGDGTYLPSDIHAM LSPILNGEAEHVIGNRFANFEPDAFTRLNLIGNRALNKLFSYAYRKKLNDILSGYRAF THEAIKTLELKETGFEIESEMTIESIKKEFIVVEVPITYLARHEDADTKLNPLKDGFR IGMTIYKLAKMHNPMFYFGAIGAVLIILGTLSGIFVVIEWIKGITHLPLTILTALLII SGIQMFIFGLMSDLVVSLHRETIRNLRSINKK" gene complement(3283..3846) /gene="" /locus_tag="" /db_xref="2116516..2117079" CDS complement(3283..3846) /gene="" /product="TATA-box-binding family protein" /translation="MADYKEDYNIKIENVVASTKLAEEFDLTKIEAEFEGAEYNKQKF PGLVYRVSNPKAAFLVFTSGKVVCTGAKNVDDVHVVIGNMAKKLNDIGIETIKDPVIT VQNIVASADLHAVLNLNAIAIGLGLENIEYEPEQFPGLVYRIDDPKVVVLIFSSGKLV VTGGKSPDHCERGVEVVRNQLDGMGLL" gene complement(4097..4336) /gene="" /locus_tag="" /db_xref="2117330..2117569" CDS complement(4097..4336) /gene="" /product="hypothetical protein" /translation="MSVKDDIHEQIKGALQSVDFPINIPEELLNAFPEGADTTCKSGD VEVTAGEAGKLLKEDDFPFNSAKEVADTIVDRANL" gene 4463..5215 /gene="" /locus_tag="" /db_xref="2117696..2118448" CDS 4463..5215 /gene="" /product="regulatory protein ArsR" /translation="MATVDTEYKNELREIKEEISSMRKEFNRFFEYSNQQYLEQILQD MKNNFSRILIDYVVEDSKNSLNDNMVQDCKMKDFCESIFNDFLQETAQLLNNDSVGPG TIEQYYEQFNELKKEKAKYPKCETCFSEAAKLFEKQINLMRSLKIYEKEDDKENIQNL PVEEVVKDVCDPIANKQRLTILKSIATDTKSFTQLSKLTGLNGGNLLFHLDKLLNSGM IQQRSERGDYIITGKGYATLKGIFNIYSQIKL" gene complement(5235..6356) /gene="" /locus_tag="" /db_xref="2118468..2119589" CDS complement(5235..6356) /gene="" /product="chromosome segregation and condensation protein ScpB" /translation="MADENKKSRDKQIIEAALFAAGNTVDIQTLTRIISKSKKHTISV VQTLIEEYNGSDTGLEILDLGERYVMQVKPEFSELVSKLAPRELSSPILRTLSMIAYH QPITQSDLVDLRGNSAYDHVKELHDRGFIRTNAYGRTKLLETTPLFADYFGLESNDPE SIKQKIIELSREQSGQKGLDRWLGRKVIAVTPMYESIMELCGIEDYRVINIYNPTEDD IDSLEDVYKLIIPKGYSENVEGYYDGEIIEVSSTTFDDLIESIKKLENISDSDKSQES IDYIRDLKEKYSSKALVISRKVKPETNMVARLVNDLRLSVSADGILIGPDYGESSNGE EIGKNADILVPTHQPDIHLIDRVCKRYDAIINGLKNVEG" gene complement(6365..7228) /gene="" /locus_tag="" /db_xref="2119598..2120461" CDS complement(6365..7228) /gene="" /product="chromosome segregation and condensation protein ScpA" /translation="VVKNVETDQVSKNVYEIESGSFGENKNDTNHDPEYIKTFQMLGL DESQIELSDDVMNEPVEMLVNLANDGDIDPWDIDIVDITDKFLDKIEQMKLMDLRISA RTLLYASVLLRMKSTGIIQEEEEDEDEEPDSLEMDGEIEFSEVEDYPVPNLPVRRNSK RPVTLNELVTELKKAEKVESRRKERNHSKKEIDRKEEKEQSSTDEVLDIAHEEDITGR AEGLYEKLEEMFQNKSYTSFSEISYGERSEKVMTYLSLLFLAADRKIKLNQEELFGEL YIFPGNGVSEG" gene complement(7233..10757) /gene="" /locus_tag="" /db_xref="2120466..2123990" CDS complement(7233..10757) /gene="" /product="chromosome segregation protein SMC" /translation="VYIKEIEFLNFKSFGKKVKIPFFDDFTTISGPNGSGKSNIIDGI LFALGLSNSRTMRAEKLTDLIYNPDSSNKPQYAQVKIRFDNSDNEMPVEADEVEITRK IKETGSGYYSYFYFNGKSVSLKDIHNYLAKAKVTPEGYNVVMQGDVTQIITMTPVERR KIIDEIAGVSEFDNKKERAMNELETVREHIERVDIIIEEVNNQLDKLKDERDQALKYQ SLKQEKAKYEGFVILSKLKDAKKELESVNSDIESKNNSVEELQKSLDEKNEQLQELEK TLSDLTNQIQNMGEKEQIQIKKDIEEIRGEISRCNGSIEIAENEIQDIDTRRRKTLVD IDDAKSKVEELESKINDEEIRKESINSELSERKNELKLLQSKINDVDAKFAETRDKLS ELKNEREQIKNEKSELIREENRLLDAVRRKSAEKRDIENEIQDSKEKIESSDSDTRSV QHEIDKLNEKIESLNKDLDDLESNRSQLKEILNEHEEELRKHQQEYAQVEARVRAAEE NSKYSKAVDTVISAKNNKELQGIYGTIAELGQADEKYSTALQIAAGGRMQAVVTENDE DASEAIEYLKRYKAGRATFLPLTKLEKRRPYKDLSDKKGVVGYAIDLIDFDDKFEPAF WYVFRDTLVMDSLENARKLMGGLRIVTLDGELVEKSGAMSGGSKQQRSGLSFAAAEKE KLTKIAEKITEYDSKRNNTIKKLDDVESQISDVKQEINNHENEISKKQMQLEEISSRE ERLSQFIESKNKELEEIEESRKELKEEMDKVVADKDEKTKKENELDEKISELEEELAD SEIPELNEKADNLNEEIQRLEGRIRDTDSNINSLNLDLEYANKRISDDRELIEELDEK KSSHQGRIESFKEKIKELEDSLASKQEREKELGDELKELQDERANKQTEYDNLKKDYN SIKSKFENASNRLQALESTKSSLKEQIDELRSELEQRGIEETEEVPNYETVRTRIASI EKAMEDLEPVNMRAIDEYDEVLNRHEEMKNRRDTLSNEREQILERIEQYENLKKETFM ETFNGINKAFSSIFNELSDGTGELALDNYEEPFSGGLTLKAQPKDKSLQRLEAMSGGE KSLTALAFVFAIQSYRPAPFYAFDEIDMFLDGANSERVAQRIKKSVNGAQFIVVSLRK PMIESASRTLGVTMQENNNTSITGVKLY" gene complement(10776..11582) /gene="" /locus_tag="" /db_xref="2124009..2124815" CDS complement(10776..11582) /gene="" /product="hypothetical protein" /translation="MGNENRDFVIERLEKQVADKEQEIKKIKDSLKDSIIEEIHQELD INNLENNGSTENVEELEKRVSKIEDKVKELGKTLEGMMEELLDQKSILKNLENQSQTP TSNGYESGNSSNTKSLDSNGIDSGYAGFSGETSGSKISEYTKKFTGRKDQNIDESASG SYTQIQEIDTIQPQEQQENENNVSVEPEYIIAESGEKNHKKNPTMENSSEYIIAESGE KGSSKKGRPKRKSNEYIVADGDDSSTHNPEPEEKVEHREDEDAEIITNDK" gene complement(11685..14351) /gene="" /locus_tag="" /db_xref="2124918..2127584" CDS complement(11685..14351) /gene="" /product="SMC domain-containing protein" /translation="MKLKRLYVENIRSYEYLDLSFNNGVSVVSGANGSGKSSLLEAFF TGLFGSRTLSKEYVLADMIRKGASKASIYLELEQNGNEYIIEQGFRYDTKNDRAYNSK SVFKSNGNIVVDQATQTYDAVCKLLNMDEEAYRNCVYIRQGEIDILINATPKERQNMI DDLLQIGKLEHYRERASNAKKGVKRHLRDVDNRIKNTESEIEKIKNENPYENLNKLRE KSKNIQSKIDELNQKKDSAKSKIDELNNSITTYSELEEKKKSINEEIQDFNTKKTQMY KDIEDIKADISKKRQYLKQLQDKNSELENQIDFNIDDIENTVNKKEEEERVARENLNT VSSNRAIKENELKLKNDTLKDIDKQITESNKNIQKKKESVESVQKEIENFEISMKEWE NKKKTALENAISLGFTEDKLDNIDDTMELLNDQQKDLHGRERELQTSISEVEKRLNEH KKLLEKGKCPTCGQDLKNSSIEESTSEDEKQKKSLEEQLSKTREDLKSVQERLKKVKT ARKYSKTINDSQNEIQIIQNKIESLKKQIEDYNNNIEEEKTNINELENRKKEVNGLID ELNKEILTLKQKEETAGKEHQKVLNSLDIVKNIRNNLNEYEKIQSDINQLEYKIKSNQ DNASLLDSQITERRERLKEIKDKMGDVDIDGLRKTLKQYESAHQNITNEIDKLYQDKD SVLKEAGRLENEINRLNNLHKDLQYLENKKNYLNSVYEDSESLENMYMRIRANLREKN IKALDSLINEIFTFMYSNNAYSHIRLDSDYNFTIYEKDGTPLDPKLLSGGERAIFNLV LRCAIYRLLSYGVSNSSSSSELPPLILDEPTVFLDRGHIHQLIKLIDMMRDSGVGQIL IVSHDESLIDSADYVYQVEKDPVTNTSMISAK" gene complement(14348..15841) /gene="" /locus_tag="" /db_xref="2127581..2129074" CDS complement(14348..15841) /gene="" /product="metallophosphoesterase" /translation="MGREIKLLHTADTHIGYRQYQSESRRQDFLDAFSTVINDAIEMQ VDAVVHAGDLFDSRNPTLEDILETMRIISRLKSSNIPFLAIVGNHESKQHTQWLDLFE KMGIAVRLGYEPYKIDEVSIFGIDSVPKSKIPYFDYSVFNNYSNNSQYNLLVMHQLMK PFAFGEWDCEEVIEYTPFDVHAILLGDYHKHEKIDVNNTWVTYCGSTERTSSSERETR SYNIVTINDSGIDISRRNLPTRDFEFIPVTIKDKDNAYDDIFNTVKEYNIENSVTIVE ISGDPNITISYSEIEDYLLNQGALVPRIRDLRTGSDELDEISMDVSFSDPDEAVREEL KNMNLTKGGLLVDEIVRDMKIVKSNIDSKIDDEMEKLLEDIDFTNPVPSSSNTETQNQ NEPCKDHSNDSQDNKDNPIETGTITDKKNESENEQTSVTTESSENYNKEQPSDVIKDD TKNKPNNVLENSGYNWVEDRTDNKKHQKKKATHKKSAPKQHNLGDYL" gene 16109..16609 /gene="" /locus_tag="" /db_xref="2129342..2129842" CDS 16109..16609 /gene="" /product="IS605 family transposase OrfB" /translation="MYLTQKNHLRADKQTYETLKRLTKLSKNLYNFTLYTIRQYFFNH GKYLNKNTAYHTVKENDNYKLLPSQVAQNTVETVDGSMKSFFKLLDKKRKGEYEKPVS LPKYLDKDGNFICTFKKDQLKVIDDNIRLSLGLDYYRTYGIKYLYFKIPDNIIGQYEQ LLSHFL" gene complement(16551..17048) /gene="" /locus_tag="" /db_xref="2129784..2130281" CDS complement(16551..17048) /gene="" /product="rubredoxin-type Fe(Cys)4 protein" /translation="LTINLKEQYVCTVCSYNMVGYLPERCPFCNAPKDKFITAEKCSR GYDVQETPVTDSVTRLSSVPKLGIEHASYQINKDNKIHQIDCPSSFDTSIKPMDEIIF THFHFLGASNLYRKYFSSKVSIHQSDSDFKLCRGFSFDNTFQTSFIKNGIEAVHIDLL CCQVF" gene complement(17122..17328) /gene="" /locus_tag="" /db_xref="2130355..2130561" CDS complement(17122..17328) /gene="" /product="hypothetical protein" /translation="MNCQICGVESNSKYCQECEKILNEVVRRVGEARWNAMEDCSFIY PMIKRVAKGELTVNDIIQQLERED" gene 17418..18014 /gene="" /locus_tag="" /db_xref="2130651..2131247" CDS 17418..18014 /gene="" /product="NADPH-dependent FMN reductase" /translation="MVKVLGLSGSPRKKGNTDILLDNFLKGVKEEGVDTETIHLRDYV IQPCIGCERCRKDKTCTRLYDGDGMKLLYPKFEESKGLVMGSPSHNYNVTSWIKAFID RLYPYYNFTEDRPRNYSSRLEGQGRKAIVFGICEQPDMDGMGYTLDAMSKPLETLGYK IETKFPVTSYFDRGAVSRDEKILQSAYQEGQNLTKKFV" gene complement(18017..18736) /gene="" /locus_tag="" /db_xref="2131250..2131969" CDS complement(18017..18736) /gene="" /product="uroporphyrinogen III synthase HEM4" /translation="MTYEIMKVAVTRLHEKDDGTYNLFKKYGLDAILIPTIQSREPSD KSSMQTLLKKLESRCIDFLIFTSTLGVIKFFKWTTEIPDRTKIISVGPKTAEKINQYG YHTEVLDSYYSEHFATHLGEKVSGKTVGITRANTPDSGLKQSLQSMGATVIEGFCYEL VETPNELKDYIVDKKIDGVVFTSTKSFLASKLTNSEVKDIITVAIGPKTAESMENHDI TPTLVGSGTLDSCALLLKDIE" gene complement(18733..18939) /gene="" /locus_tag="" /db_xref="2131966..2132172" CDS complement(18733..18939) /gene="" /product="hypothetical protein" /translation="LADKKNPPVFCEKYCIICKGARSGNKICKTIQNLELKIFGDNGC PFGQARAEYYGVKPDEKLPIEDEE" gene complement(19063..19581) /gene="" /locus_tag="" /db_xref="2132296..2132814" CDS complement(19063..19581) /gene="" /product="nicotinamide-nucleotide adenylyltransferase" /translation="MHRKRAFYIGRFQPYHLGHNSIINRIADEVDEVVIGIGSAQKSH SPSDPFTAGERVMMIRNALEKEKVPNYALPIEDIQQNSLWVSHVLSRTPLFDVVYSNN PLVIQLFEEAGIPVKQSPMYQREQYSGTRIRKKMIEDNDWRHLVPDAVADIIDEIDGI TRLKNVSRTDID" gene complement(19603..20628) /gene="" /locus_tag="" /db_xref="2132836..2133861" CDS complement(19603..20628) /gene="" /product="coenzyme F420 hydrogenase/dehydrogenase beta subunit domain-containing protein" /translation="LHPKILDVIENDVCTACGACAAVCPVGAITIDKKAQIRDPNNLE LYEKGAAPSVCEDCYACGNVCPVIHGYVEDELYNVKQFFGARSSIPGQDGGVTSAILK SLLDKGEIDCVVGITRNENWETELVLMTEPSQVDQTAGTKYTYDSVISALREPFKDYD RIAVVGVPCQAHGARLIFENINDKIAVIIGLFCMESFHHETMLNDIIPKVLGLDIEQV VKMDFAKGKFWAYTKDGEGHSVKIPTVAEYARNPCHNCCDYTAVHADISIGSVGAPDG WNSVLIRTDIGEKYFKKASKDLEIMENPEPGMDLIKKLLNMKHEKNEPHYLEACEKFS FEAGGIK" gene complement(20629..21615) /gene="" /locus_tag="" /db_xref="2133862..2134848" CDS complement(20629..21615) /gene="" /product="5,10-methylenetetrahydromethanopterin reductase" /translation="LTFGIEFVPSDPVLKIAHYAKLAEQSGFDNVWVTDHFNNRDVYT TLAVLANNTNSIKLGTGVTNPYTRNIGITASSIGAINEISGGRAILGIGPGDKATFDS MGISWEKPLTTTKESVTALRGYFAGENVSLDGEMVKVGGAKMAFKTGDIPIYLGAQGP KMLQLAGEVADGILINGSHPRDFDVALDKIKEGAENAGRDMNDIDIAAYTCFSIDKDA EKAKQEAKVVVAFIVAGSPDVVLERHGIDPEAKKNISDAISKGDFKSLMGDMVTDDMV NAFSVCGTPEDCKQRVDELFNTGVTQIVVGSPIGPKKEKAIKLIGKEIIGGK" gene complement(21926..22156) /gene="" /locus_tag="" /db_xref="2135159..2135389" CDS complement(21926..22156) /gene="" /product="hypothetical protein" /translation="MVEYDYKYNGSRNKLTNKYNLRNQVPRLKEEKPFLKTVYSSVLK NVAIRLAKSYENFFQIPEVGHPQHRKMVPIIL" gene 22382..22504 /gene="" /locus_tag="" /db_xref="2135615..2135737" CDS 22382..22504 /gene="" /product="desulfoferrodoxin dfx domain-containing protein" /translation="LAVSSVGEKYVCEICGNEVEVTVVGGGVLVCCGEEMELVE" gene 22567..22806 /gene="" /locus_tag="" /db_xref="2135800..2136039" CDS 22567..22806 /gene="" /product="hypothetical protein" /translation="MLCYDCAQQGKDVDTIGICILCGRGICKEHSVREDLPVMKGEYD VELECGMGVECSTKDMQHLPQMLCPTCHKVVKENY" gene 22821..23039 /gene="" /locus_tag="" /db_xref="2136054..2136272" CDS 22821..23039 /gene="" /product="hypothetical protein" /translation="MMKCYDCMNEGVDKESTGTCTFCGKGICSTHTKKLELPVSVGTY PNFKRLPEPLPKFVCNECADNIITDSFD" gene 23066..23446 /gene="" /locus_tag="" /db_xref="2136299..2136679" CDS 23066..23446 /gene="" /product="carboxymuconolactone decarboxylase" /translation="MTDEKEEHLEPDDLLKEMGEKIGYTPHILEILGELDPDHLTRYN ACNKRILSDGEIPSKYKVLMALAVVASKQCERCAQTQMINAINHGATKEEIMETMDVI GITSGAPAVAACRDALKLLQKETE" ORIGIN 1 ttactttgca aggtcgtagt gctggtttac aattttaaga gcacagaagt ctccgcacat 61 agtgcaggcg tcttcatctt ctggagctct gtcatttctg atggttcttg cagtctggga 121 gtcaatggca agactgtaca ttttttccca gtcaaggttg cagcgtgcac gtgccatatc 181 aaggtcattg tctcttttgc caagttttac catgtctcct acatgagcag caatctttga 241 ggctttgaca ccctctctta catcatcaac gtttggaagt gcaagatgtt ctgcaggggt 301 gacgtaacac aggaaatcac atccggctgc acttgaagca gaggcaccaa tggatgtaac 361 aatatggtcc tgtcctggtg ctacatcagt gaccagtggt ccaagcatat agaatggtct 421 gtttccgctc atggatttca tgagtttgac attggtctcg atttcgtcca ttggtacgtg 481 accaggacct tcaactatta cctgcacacc ttcgttctgc gcctgctcag caagttcagt 541 gtttataatc aattcctgaa tttgtgctct atcagtagca tcatggactg cacctgcacg 601 cattccattg cccattgaga gaactacttc gtgttctttc aggatttcaa gcaagtaatc 661 aaattcactg tagagagggt tttctttttc attgtaaagc atccatgtac tcatgaatgc 721 accgcctctg gaacagagtc ctccgtaacg gccatgtttt ttaagcctgt ccagtgtgat 781 gttgttaact ccagtgtgta tagccatgaa atttgtacca agttttgcct gttcttcggt 841 agctttgaac aggtcatctt cggtcatgtc agtaatagaa ccgcgttttt gtgcagcttc 901 tatgaatgcc tgatagagtg gtacagaccc aactgacaag gatgtattat caacaacttc 961 tttccttacc tcaaggaaat ctccgcctgt accaagttcc atgagagtgt ctgcaccagc 1021 ttcttctgca gcttttgctt tttcaacctc caaacctatg ttggaaatat cggatgatga 1081 gccgatagaa gcattcactt ttgttgaaag cccttcacca attccacaaa gtttaacatc 1141 tctgtaggga gaggtgggta taacaatcct tccgttggct attcctcttc ttatatactc 1201 agggtcaaga ccctcttttt gtgcaacaac tttcatttca tctgttattt ttccattgac 1261 tgcatcttct aatagtgtca taagtagacc tcattaaagt taactttgtt attgttcgtt 1321 tctatgcaaa tattttattt aaaacttgtc aaaaaatatt ctttagtttt aatcaagtaa 1381 atttgattta aaatttattg gtaatgaatt gctataggaa tataaacaaa ttcagtttct 1441 taaatctttg ataatgattt gtttaatatt gtattatata actaaaaggc tattataaaa 1501 ataaatagtt cagtttaaat ttataaaact atttaagcaa tagtgataac tcaaattttt 1561 ctgtagtaaa aacccaaaaa ggtattatat cttgggttat attattgtta taatagtagt 1621 ttagtggtat aatttatatt attaaactac cagtgatgaa gaaaggtaac tgtttggaat 1681 atgtttgtat aatagatcat tcctcccctc tcttcaatat aaaataagga taagaggcat 1741 cgtaatatac atatgcccca tagtaaataa cccactcccc aacccgcatt ggattgagag 1801 cctccccttg actctcaatc gcaggttttc ggatcgaaag aaaaaccact aaaactttcg 1861 accacgtatc ctttctaagg ttgtaatcgt atttaacaaa aacgctaact aaaatttaac 1921 agcgttgaaa attttaacgc ctttaaatat tataccggtt tatttaatat caaacccaat 1981 aagtttttta tccttttatt tctaaaaggc ttgtatgagg atatgggata tacctcctga 2041 taaattatgc cgaaatcatt tacttggcga acatagagaa ttacatgcat tgtggtcgat 2101 aattattaac aacaaaaagg cttattctaa tcatcctgaa actctacgct ggaaggataa 2161 acttagagcc ctgcatttga gacatgaaaa actggtcgaa gaaatggata aaagaggata 2221 taatcatcaa tccccacttg atgtcaggtt tgctacaggc agtgatacac aagatgaatt 2281 catagattct tatgagaagc aggtaaagat tttgaaagaa aaaaattgcg gatgtagtgt 2341 ttaaatttaa gcttattttt tatttattga acgaagatta cgtattgttt ctctgtgaag 2401 tgatacaacc aaatcgctca ttaacccgaa tatgaacatc tgtatacccg agataataag 2461 aagtgctgta agaattgtca gaggcagatg ggtaatccct tttatccatt caattaccac 2521 aaaaatgccc gaaagtgtgc caagaataat tagcactgca ccgatggcac caaaataaaa 2581 cataggattg tgcatttttg caagtttgta tattgtcatt cctattctga aaccatcttt 2641 tagcgggttg agtttggtat cggcatcctc atgtcttgcc agataagtga ttggaacttc 2701 aaccacaata aattcttttt tgatgctttc aatcgtcatt tctgattcaa tttcaaaacc 2761 ggtttcttta agttccagtg ttttgatagc ttcatgggta aaggcacggt atccagacag 2821 gatatcattc aattttttcc gatatgcata actgaataat ttattaagag cccggtttcc 2881 tataaggttt agtcgggtaa aagcgtcagg ttcaaaattt gcaaaacggt tacctataac 2941 atgttctgct tctccattta gtattggaga tagcattgca tgaatatccg atggtagata 3001 cgttccgtcc ccgtctacca tcacaacata ttcactttct attatgttga aagcttcctg 3061 taccgcctga cctttaccct taccgctctg gacaactata ctggctcctt ctccttctgc 3121 cagttcacag gttctatctg tgctgttgcc gtcgataacg aatatattgt caaatccttc 3181 agatttgaaa ccccttatta tttctacaat ggtagattct tcattaaggg tgggtattag 3241 tatacaaacg ttttcgtttt ctggtgtact cacattcatc cctttacagg agccccatac 3301 catctaactg gtttcttacc acttctaccc cgcgttcaca gtgatcaggg gatttacctc 3361 cggtaacgac cagttttcct gaactaaata tcaaaactac aacttttggg tcatcaatac 3421 gatatactaa accagggaac tgttcgggtt catactctat gttttcaaga ccaagaccta 3481 tagcaatagc attcagattg agtactgcat gcaggtcagc agatgccaca atattctgaa 3541 cagtaattac agggtctttg atggtttcaa taccgatgtc attgagtttt ttagccatgt 3601 tcccgataac aacatgcacg tcatccacat ttttggcacc tgtgcagaca actttaccag 3661 aagtgaaaac aaggaaagca gcttttggat tggaaaccct gtatacaaga cccgggaatt 3721 tttgtttgtt gtattctgcg ccttcaaatt cggcttctat ttttgttaaa tcaaattctt 3781 ctgcaagttt ggtggaagcc accacgtttt cgattttgat gttgtaatcc tctttataat 3841 ctgccatatt tttggtcctg aatatttgat taaactatat tttttatatc cttatatata 3901 atagcaaaaa gtaatttatt catttataaa agttacttaa atacatgttt cttttaaaaa 3961 tgttttggat atttgtaatt acaacatcgc aaaattatag tattaaaagt aaaaatatat 4021 attttaaaat tagaagtatg aaacaatagg ggcacagtcc tttaatgccc ctatataaat 4081 ttataatcca gcagggttta taagtttgct ctatctacaa tagtgtctgc tacttctttt 4141 gcactgttaa atgggaaatc atcttctttt agtagttttc ctgcttctcc agcggtgact 4201 tcaacatctc ctgatttgca ggttgtatct gctccttcag ggaatgcgtt caataattct 4261 tcaggtatgt ttatcggaaa atctacactc tggagagctc cttttatctg ttcatggatg 4321 tcatctttga cactcatatt ttatcaccaa taccatatat tatcagtcat aaatatatag 4381 ttaatcgtta taattatata ctaagaactt atttagtgta tgacaataac ttagttttga 4441 tatagattta tggaggtcca tcaatggcta ctgttgacac tgaatataaa aacgaactcc 4501 gggaaataaa agaggaaatc agttccatgc gtaaggaatt caaccgtttt tttgaatatt 4561 cgaatcaaca atatcttgaa caaatattgc aggatatgaa gaacaacttt tccagaatac 4621 tgattgatta tgttgtcgag gacagcaaaa actcacttaa tgacaatatg gtacaggact 4681 gtaagatgaa agatttttgt gaatcaatat ttaatgattt tctgcaggaa actgcccaac 4741 tattaaacaa tgacagtgtg ggcccgggaa caatcgagca gtattatgaa caatttaatg 4801 aattgaaaaa agaaaaagca aagtatccaa aatgtgagac atgtttttct gaggctgcaa 4861 aactgtttga aaaacagatt aatctcatgc gttcattaaa gatatatgaa aaagaagatg 4921 ataaagaaaa tattcaaaat cttcccgtgg aagaggttgt taaagacgta tgtgacccca 4981 tagcgaataa acaaaggctt acgatattaa aatctattgc aaccgataca aaaagtttca 5041 cacagctatc caaattaaca ggtcttaatg gcggtaacct gctctttcat ctcgacaaac 5101 ttcttaattc aggtatgata cagcaaagaa gtgaaagggg agactatatt ataactggga 5161 aaggatacgc aacattaaaa ggaatattca atatttattc gcaaataaaa ctataatact 5221 gataaaacat cagttttaac cttcgacgtt tttcagtcca ttgattattg catcatatct 5281 tttacagact ctgtcaatca gatggatgtc gggttgatgg gtgggaacaa gtatatccgc 5341 atttttacca atttcctcac cattacttga ttcgccataa tcaggcccga ttaaaatacc 5401 atcggcggat acactgagtc tgaggtcatt caccagtctt gctaccatat ttgtttctgg 5461 tttgacttta cggctgatga caagtgcttt tgatgaatat ttctctttta aatccctgat 5521 ataatcgatg ctttcctgtg atttatcact gtctgatatg ttttccagtt tctttatcga 5581 ttcaatcaga tcgtcgaaag tagtagagct aacttcgatg atttctccat cgtaatatcc 5641 ttctacattt tctgaatatc ctttcggaat aataagtttg taaacatcct ccagtgaatc 5701 gatatcatct tcagttgggt tatagatatt aatgactctg taatcttcga ttccgcacag 5761 ttccataatt gattcgtaca tcggggtgac cgctataacc ttcctcccaa gccatctgtc 5821 aagacccttc tgtccgctct gttcacggga aagttctata attttttgtt ttatcgattc 5881 agggtcattg gattcaagtc caaaataatc ggcaaaaagt ggagtggttt caagtaactt 5941 tgtccttcca tatgcatttg tgcggataaa tcctctatca tggagttctt taacatggtc 6001 ataggcagaa ttacctctta aatctacaag gtcggattgg gtgatgggtt ggtggtaagc 6061 tatcatggaa agggttctaa gtataggtga actgagttct cttggagcaa gtttgctgac 6121 aagttcgcta aattcaggtt taacctgcat cacatatctt tctccaagat ccagtatttc 6181 aagtccagta tcactaccat tgtattcttc aataagtgtt tgaacaaccg atatggtatg 6241 ttttttggat ttgcttataa ttcttgtgag tgtctgtata tcaactgtat taccggcggc 6301 aaaaagtgct gcttcgataa tttgtttgtc tcttgatttt ttgttctcat cagccataaa 6361 acatcttacc cttcggacac tccattaccg ggaaatatat aaagttctcc aaaaagctcc 6421 tcctgattca atttaatttt tctgtcagca gcaagaaaca gaagggacag ataggtcatg 6481 actttttcag aacgttcacc ataggatatt tcggaaaaag aagtgtagct cttgttttga 6541 aacatttctt ccagtttttc gtacaaacct tccgcacgac cggtaatatc ttcctcatgt 6601 gcaatatcaa gtacttcatc agtagaggat tgttcctttt cctcttttct atctatctct 6661 tttttactgt gatttcgctc ttttcttctg gactctactt tttcagcctt ttttagttct 6721 gtaacgagtt catttaaagt aacaggacgc ttggaatttc gccttacagg aagatttgga 6781 acagggtaat cctctacttc tgaaaattcg atttcaccat ccatttccag agaatcgggc 6841 tcttcgtcct catcctcttc ttcttcctgg atgattccgg tggatttcat acgaagtaaa 6901 acggaagcat aaagcaaggt tcttgctgat atccttaaat ccatcagttt catctgttca 6961 atcttgtcca gaaatttatc tgtaatatca acaatatcaa tatcccatgg atcgatatct 7021 ccatcatttg caagatttac cagcatttca acaggttcat tcattacatc atcggataac 7081 tcaatctggg attcatccag accaagcatc tgaaaagttt ttatgtattc agggtcatgg 7141 ttggtatcgt ttttattttc cccaaatgaa cctgattcaa tttcgtatac gttttttgat 7201 acctgatctg tttccacgtt tttcaccaca gtttcaatac agtttaacgc ctgtgatact 7261 ggtattgtta ttctcctgca tggtaactcc aagagtcctt gaagcagatt caatcatggg 7321 cttccggagt gagaccacta taaactgagc accgttcacg gattttttaa tacgctgtgc 7381 gaccctttca gaattagcac catcaaggaa catatcgatt tcatcaaagg catagaatgg 7441 agctggacga taagattgga ttgcaaaaac aaatgcaaga gccgtcaggc ttttttctcc 7501 acctgacatt gcttccagac gttgcaggct tttgtctttg ggctgggctt taagagtaag 7561 tcctccagaa aacggctctt cataattatc aagagccagt tcacctgttc catctgaaag 7621 ttcattgaat atggatgaga aagctttatt tattccatta aatgtctcca tgaacgtttc 7681 ttttttgagg ttttcatatt gctctatacg ttccagaatc tgctcccttt catttgaaag 7741 ggtgtctctt cggtttttca tctcttcatg tctattcaaa acctcatcat actcatcgat 7801 agctcgcata ttgacaggtt caaggtcttc catggctttt tcaatcgatg caatccttgt 7861 acgtactgtt tcatagttgg ggacttcttc agtttcctca attcctcgct gttccagttc 7921 gcttcttaat tcatctattt gctctttaag agaacttttt gtagattcaa gtgcctgaag 7981 tcggttactt gcattctcaa atttggattt gatggaatta taatcttttt tgaggttgtc 8041 atattcggtt tgtttgttcg ccctctcgtc ctgtaattct ttgagttcat cacccagctc 8101 tttttccctt tcctgtttac tggcaagact atcttccagt tctttgattt tttctttaaa 8161 ggattcaata cgaccttgat ggcttgattt tttctcatca agctcttcaa tgagttccct 8221 atcatcgcta attcttttgt tggcgtattc aaggtcaaga ttcaatgaat tgatattact 8281 gtcagtatca cgtatacgtc cctccagtct ctggatttct tcgttcagat tatcagcttt 8341 ttcattgagt tcgggtattt cagaatcggc aagttcttct tcaagttctg atattttctc 8401 atcaagttcg ttttcttttt tggttttctc atccttatct gcaacgacct tatccatctc 8461 ttctttgagt tctttacgtg attcttctat ttcttcaagt tctttgtttt tggattctat 8521 gaattgggat agtcgttcct ctctgcttga gatttcctca agttgcatct gttttttgga 8581 tatttcattt tcgtgattgt tgatttcctg cttaacatca gaaatctggc tttcaacatc 8641 atcaagtttt ttgattgtgt tgttgcgttt ggaatcgtat tcggtgattt tttctgctat 8701 ttttgtaagt ttttccttct cagccgcggc aaatgaaaga cctgaacgct gctgtttgga 8761 cccgccactc atggctccgc ttttttcgac aagttctcca tcaagggtta ctattcggag 8821 tccgcccatc agtttgcggg cgttttccaa actatccatt accagagtat ctctgaatac 8881 gtaccagaaa gcaggttcaa atttatcatc aaaatcaata agatctatcg cataaccaac 8941 aacacctttt ttatccgaga ggtctttgta aggtctgcgt ttttcaagtt ttgttagagg 9001 gagaaatgtt gctcttccag ctttataccg ctttaaatat tcgattgctt ctgatgcatc 9061 ttcatcattt tcagtaacaa cagcctgcat acgtccgcct gcagctatct gaagagcggt 9121 agaatatttt tcgtctgcct gtcccagttc agcaatagtt ccatagattc cctgaagttc 9181 cttgttattt tttgcagata tgaccgtatc aaccgctttt gagtatttgc tgttttcctc 9241 tgcagcacgg actcgggctt caacttgtgc atattcctgc tggtgctttc ggagttcttc 9301 ttcatgttca ttcaatattt ctttaagctg ggagcggttg ctttcaaggt catcgaggtc 9361 tttgttcagt gactcgattt tttcgttcag tttatcaatt tcatgttgaa cagagcgggt 9421 atcgctatct gaagattcga ttttttcttt agaatcttgt atttcgtttt ctatatccct 9481 tttttctgcg gatttacgtc ttactgcatc aagcaaacgg ttttcttcgc gaatcagttc 9541 acttttttca ttcttaattt gttcacgttc atttttgagt tcagacagtt tgtcccgggt 9601 ttcggcaaat ttggcatcaa catcattgat tttgctctgc agaagtttca gttcgttttt 9661 acgttcgctg agttcagaat tgatactttc tttgcgtatt tcttcatcat tgatttttga 9721 ttcaagttct tcaaccttag attttgcatc atcaatatct acaagggtct tacgtcgtcg 9781 ggtatctatg tcctgtattt cgttttcagc aatttcaata ctgccattac accttgaaat 9841 ctctcccctt atctcttcaa tatccttttt tatctggatt tgttcctttt cacccatatt 9901 ctggatttgg tttgtaaggt cagagagggt tttttcaagt tcttgtagct gttcattctt 9961 ttcatccagt gatttttgta gttcttctac tgaattgttc ttggattcaa tatcactgtt 10021 tacagattca agctcttttt ttgcatcctt taattttgaa aggattacaa aaccttcata 10081 ctttgctttt tcctgtttca atgattggta tttaagtgcc tgatcccgtt catccttgag 10141 tttatcaagc tgattgttaa cttcttcgat tataatgtct actctttcaa tgtgttctcg 10201 aacggtttca agttcattca tcgctctttc ttttttatta tcaaattcgg atacacccgc 10261 gatttcatcg atgatttttc tcctttctac aggggtcatg gttataatct gggtgacatc 10321 tccctgcatg acaacattgt atccttcggg tgtaactttt gctttggcga gataattatg 10381 aatgtctttc aaacttacag attttccatt aaaataaaaa tagctgtaat acccacttcc 10441 cgtttccttt atttttcgcg taatctcaac ttcatcagct tccacaggca tttcattgtc 10501 tgagttgtca aaacggattt taacctgtgc gtactgtggc ttattactgg aatcgggatt 10561 ataaatcagg tctgtaagtt tttcagcacg catagttctt gaattggaca gacccaatgc 10621 aaacaggata ccatcaatta tgtttgattt gccacttccg tttggtccgg atatggttgt 10681 aaaatcatca aaaaatggta tctttacctt tttaccaaag gatttgaaat tcaggaattc 10741 aatttccttt atgtacacgt gcaacctctt taaaaattat ttgtcattag tgataatttc 10801 agcatcttcg tcttctctat gttcaacttt ttcttcaggt tcgggattat gagtagatga 10861 atcatctcca tcggcaacaa tatattcatt gctttttctt ttcggtcttc ctttttttga 10921 tgagcccttt tctccactct cagcaattat atattcagaa ctgttttcca tagtgggatt 10981 tttcttgtgg tttttctccc cactttcagc aattatatat tcgggttcta cagaaacgtt 11041 gttttcattt tcttgttgct cttgaggttg tatagtatcg atttcctgta tttgtgtata 11101 actaccagaa gcactttcat caatgttctg gtcttttctt cctgtaaatt tttttgtata 11161 ttctgatatt tttgatcctg aggtttcgcc tgaaaagcct gcatagccgc tatcaatacc 11221 gttagaatca agggattttg tatttgaaga attaccagat tcatagccat tcgaggttgg 11281 agtttgggat tgattttcga gatttttaag aattgatttt tggtccagca attcttccat 11341 catgccttca agtgtttttc caagttcctt gaccttatct tcaattttgc tcacacgttt 11401 ctccagttct tctacatttt ctgttgagcc gttgttttca aggttgttaa tatcaagctc 11461 ctgatgaatt tcctcgatga ttgaatcttt gagtgaatct tttatttttt tgatttcctg 11521 ctctttatca gcgacctgtt tttcaagcct ttcaataaca aaatccctgt tttcattgcc 11581 catattttat gttacctcgt aaattcattc atccctcaaa ttttatatat ttaatcttat 11641 aagattttta tgtacgtaga gatatgatat aagttgtggt tgtttttatt ttgcagaaat 11701 catggatgta tttgtaacag ggtctttttc cacctgatat acgtaatcag cagaatcgat 11761 taaactttcg tcatgggata ctatcagaat ctgtcctact ccagaatccc tcatcatatc 11821 aataagtttt ataagctggt ggatatgccc tctgtcaagg aaaacagtcg gttcatcaag 11881 tattagaggt ggcaattctg aactgctgga actgttgctg acaccatatg ataagagcct 11941 gtaaatggca catctaagaa ccagattgaa tattgcccgt tctccaccac ttaatagttt 12001 ggggtcaagc ggggtgccgt ctttttcata aatggtgaaa ttataatcag aatcgagccg 12061 tatatgtgag taagcattgt tggaatacat gaaagtgaat atttcattta tcaatgaatc 12121 cagtgctttt atattcttct cacggaggtt ggcacggata cgcatataca tattttcaag 12181 agattcagaa tcttcataga cactattaag gtaatttttt ttattttcca gatattgtaa 12241 atctttgtgc aggttgttca ggcggttaat ttcgttttcc agtcgaccgg cttctttgag 12301 aacgctgtct ttatcctggt ataatttatc aatttcgttc gtaatgtttt gatgggcgct 12361 ttcatattgt ttgagtgttt ttctcaaacc atctatgtca acatcaccca ttttatcctt 12421 tatttctttt aaccgctctc tgcgttctgt aatttggctg tcaagtagag atgcgttatc 12481 ttggttgctt tttatcttgt attccagctg atttatatcg ctctggattt tttcgtattc 12541 gttgaggttg tttcggatat ttttaacaat atcaagacta ttcagaactt tctgatgttc 12601 ttttcctgca gtctcttctt tttgtttcag ggtcaatatt tctttgttaa gttcatcgat 12661 taatccattg acttcctttt tgcggttttc aagttcattg atatttgttt tttcctcttc 12721 tatgttgttg ttataatctt ctatctgttt ttttagcgat tcgattttgt tctggattat 12781 ctgtatctca ttttgactat cgttgatagt tttactgtat tttctggcgg tttttacttt 12841 tttcagtctc tcctgcacac tttttaaatc ttctctggtt tttgaaagct gttcctcgag 12901 ggattttttc tgtttttcat cctctgatgt agattcttca atgctggagt ttttcaaatc 12961 ctgtccgcat gtggggcatt tacccttttc gagcaatttt ttatgttcgt ttaaacgttt 13021 ttccacttct gatatcgagg tctggagttc acgttctctg ccatgaaggt ctttttgctg 13081 gtcgtttaga agctccatag tgtcatcgat gttgtccagt ttatcctcgg taaatccaag 13141 ggatattgcg ttttcaagcg cagtcttttt cttgttttcc cattctttca tggaaatttc 13201 aaaattttcg atttcttttt gaaccgattc tacggattct ttctttttct ggatattttt 13261 attactttca gtaatctgtt tgtcaatatc ttttaaggta tcatttttga gtttcagttc 13321 attttccttg atagcccggt tactggatac agtattcaga ttttctcttg caacccgttc 13381 ttcttcttcc tttttattta cagtgttttc aatgtcatca atattgaaat cgatttggtt 13441 ttcaagttct gaatttttat cttggagttg ttttaaatac tggcgctttt tgctgatatc 13501 tgcttttata tcctcgatat ccttatacat ctgggttttt ttggtgttga aatcctgaat 13561 ttcttcgttt atcgatttct ttttctcttc cagttctgaa taggtagtaa tactgttatt 13621 aagttcatcg attttggatt tggcgctatc ttttttctga ttgagttcat cgattttgga 13681 ctgtatattt ttggattttt ctctgagttt gttcaggttt tcataggggt tttcattttt 13741 aatcttttca atttcagact ctgtgttttt gattcgatta tccacatctc ttaaatgccg 13801 ttttacacct tttttagcat tgctggctcg ttctcgataa tgttccagtt ttccgatttg 13861 taataggtca tcgatcatat tctggcgttc tttaggggtt gcattaatga gtatatcaat 13921 ttcaccctgc cttatgtaca cacaatttct gtacgcttct tcatccatgt tgagtaattt 13981 gcaaacagca tcataagtct gggtagcttg gtctaccact atattaccat tggatttaaa 14041 tacggattta gaattgtaag ccctatcatt tttagtatcg tatctgaaac cctgctcgat 14101 tatgtattca tttccatttt gttccagttc cagatatata ctggcttttg aagcaccctt 14161 gcgtatcata tctgccagaa catattcttt tgaaagtgtc ctgcttccaa aaagcccggt 14221 aaaaaaagcc tcaagtagac tggattttcc actcccgtta gcaccggata ctactgatac 14281 accattgtta aatgaaaggt cgagatattc ataacttcta atgttttcga catataaacg 14341 tttgagtttc atagataatc tccaagattg tgctgtttgg gtgcggattt tttatgtgtt 14401 gcttttttct tttgatgttt tttattatct gttctatctt caacccagtt gtaaccagaa 14461 ttctctaaaa cattgttagg tttgtttttt gtatcatctt ttataacgtc tgaaggttgt 14521 tctttattgt agttttcaga tgattcggtt gttactgatg tctgctcatt ttcagattca 14581 ttttttttat cggttattgt tcctgtttct ataggattat ctttattatc ctgactgtcg 14641 ttactgtgat ccttacaggg ttcattttga ttctgggttt cagtattaga agaagatggg 14701 acagggtttg tgaaatcgat atcttcaagt agtttttcca tctcgtcatc aatttttgaa 14761 tctatgttac ttttaacaat tttcatatcc cgtacaattt catctaccag taatccgcct 14821 tttgtaaggt tcatattttt gagttcttcc ctgacagctt cgtctgggtc tgaaaatgaa 14881 acatccattg atatctcgtc cagttcatcg ctgccggttc tcaaatccct tattcttggg 14941 acaagagcac cctggtttaa cagataatct tctatttcac tgtatgatat tgtgatgttt 15001 ggatcaccag aaatttctac aatggtaaca ctgttttcga tattgtattc tttaacagta 15061 ttgaaaatat catcatatgc attatctttg tcttttatcg taacaggtat aaattcgaaa 15121 tcacgagttg ggagattacg tctgctgata tctatacctg aatcgtttat tgtaacaata 15181 ttgtaggagc gtgtttcacg ttctgatgaa ctggtacgtt cggtactccc gcagtatgtg 15241 acccatgtat tgtttacgtc tatcttttca tgtttgtgat aatctccaag cagaatggca 15301 tgtacatcaa atggagtata ttcaatcacc tcttcacaat cccattctcc aaaggcaaat 15361 ggtttcatga gttgatgcat tacaagaagg ttgtattgtg aattattaga ataattatta 15421 aaaacagaat agtcgaaata ggggattttt gattttggaa cactatcgat tccaaagata 15481 ctaacctcgt ctattttata aggttcgtat ccgagcctta cagcaatacc catcttttca 15541 aaaaggtcaa gccattgagt gtgctgttta ctttcatggt tgcctacaat agccagaaat 15601 gggatattcg atgatttcaa acgtgaaata atcctcatag tttccagtat atcttcaagt 15661 gttgggtttc ttgaatcaaa aaggtctcca gcgtgtacaa cagcatcaac ctgcatttca 15721 atggcgtcat ttataacagt ggaaaaagca tcaagaaaat cctgtcggcg agattcgctc 15781 tggtattggc ggtagcctat atgtgtatca gcagtgtgga gtaattttat ttcacgtccc 15841 atgtttgatt ctataggaat ctcaacactt ttaaggttga tgtatttttt ccattagctt 15901 acaataaatt ttaaatgatg agtgtaattt tatccagatt ttgataccag caggcttttg 15961 tatcttggat accagtcttt aaaatccatg acgtaattga ctccacagat tttgtttata 16021 aagatgaaga aaaccacgat gtctttagca tcgtggtatg ataaagagtc aaaaaaatat 16081 aagtattttg ctaaacgatt gtataatgta tgtatctgac ccagaagaat catctccgtg 16141 ctgataaaca gacctatgaa actttgaaga ggttgaccaa gctgtccaag aacctgtaca 16201 atttcacatt gtatacgatt agacaatact ttttcaacca tggtaaatat ctcaataaga 16261 atactgctta tcatacggtt aaagagaacg acaactacaa gcttctgcct tctcaggttg 16321 cccagaatac agtggaaact gtagacggca gtatgaaatc gttcttcaag cttctggata 16381 agaagagaaa aggagaatat gaaaaacctg tttctcttcc aaagtatctg gataaagacg 16441 gtaacttcat atgtacgttc aagaaagatc aactgaaggt tatcgacgac aatatcaggt 16501 tatcgttagg tttagattat tacagaactt atgggattaa atacctatac ttcaaaatac 16561 ctgacaacat aataggtcaa tatgaacagc ttctatccca ttttttataa aactggtttg 16621 gaatgtattg tcaaaactaa atcctctgca taatttgaaa tcagaatctg attgatgaat 16681 ggatactttt gatgaaaaat attttctgta tagattggat gcaccaagaa aatggaaatg 16741 tgtgaatata atctcatcca ttggttttat gctggtgtca aaacttgacg ggcagtctat 16801 ctgatgaatt ttgttgtctt tatttatctg atatgaagcg tgttcgatac ccagttttgg 16861 aacagaactt aacctggtaa cagaatctgt tacaggtgtc tcttgtacat cataacctct 16921 tgaacatttt tcagcagtta tgaatttgtc tttgggagca ttgcagaaag gacacctttc 16981 aggtaaatat ccaaccatgt tgtaactgca tacagtacat acatattgct ctttcaggtt 17041 tattgtcaat catatctcct ctgatggaaa aacagtttct attaattggt aatggttata 17101 aaatgaaaag gaaaactgga aattaatcct ctctttccaa ctgctgtatt atatcgttta 17161 ctgtcagttc tccttttgca actcttttta tcattggata tataaatgaa caatcttcca 17221 tagcattcca gcgcgcttcc cccactcttc taactacttc attaagaatt ttttcacatt 17281 cctgacagta tttactgtta ctttccactc cgcaaatttg gcagttcata agactcctcc 17341 cttaataaat taaagtgtac taatatttaa ataaattgtg ttgggcagtt atttataata 17401 aaaatttgga gattgaatat ggttaaagta cttggtttaa gtggcagtcc caggaaaaaa 17461 ggaaacaccg atatattgct cgataatttt ttaaaaggag ttaaggagga aggagttgat 17521 actgaaacaa ttcatctgcg tgattatgta attcagccgt gtataggatg tgagcggtgc 17581 cgcaaagata aaacctgcac acgtctctat gatggtgatg gtatgaagct tttatatcca 17641 aagtttgaag agtcaaaagg tcttgtgatg ggttctcctt cacataatta caatgtcaca 17701 tcctggataa aggcttttat cgaccgtctc tatccttatt ataattttac tgaggacaga 17761 cccagaaact attcatcccg tttggaagga cagggtcgaa aagcgattgt ttttgggata 17821 tgcgaacagc cagatatgga tggcatggga tatacattgg atgccatgtc aaaaccactt 17881 gaaacactgg ggtacaaaat agaaacaaag ttcccagtaa ccagttactt tgatagggga 17941 gctgtatcca gagatgagaa aatattacaa tcagcctatc aggaaggtca aaacttgacc 18001 aagaaatttg tataatttta ttctatatct ttaagcaaaa gagcacatga atcaagggta 18061 cctgaaccta caagagtggg tgttatatcg tgattttcca tactttcagc tgtttttggt 18121 ccaattgcca ctgtaatgat atctttgact tcagaatttg taagttttga agctagaaaa 18181 gattttgtgc ttgtaaaaac aacaccatcg atttttttat ccactatata atctttcaat 18241 tcattagggg tttctacgag ttcataacag aacccttcaa taacagttgc acccattgac 18301 tgcagagatt gtttaagccc agaatcaggt gtatttgctc tggtgatgcc aacagttttg 18361 cctgatacct tttcaccaag atgtgttgca aaatgttcag aatagtatga atccagaact 18421 tctgtgtggt atccatactg gtttatcttt tctgctgttt tggggcccac actgattatt 18481 ttggttctat caggaatttc agtagtccac ttgaaaaatt tgataacacc aagtgtactt 18541 gtaaaaatga gaaaatctat acaccgcgat tccaactttt ttagaagagt ttgcatagat 18601 gatttatcag aaggctcacg tgattgtatg gtgggtatta gaattgcatc aagtccatac 18661 tttttgaaaa gattgtatgt tccatcatct ttttcatgta aacgtgttac ggcaaccttc 18721 ataatttcat aggtcattct tcatcttcaa taggtagctt ttcatcaggt ttaactccat 18781 aatattcagc tcttgcttga ccgaaaggac acccattatc tccaaaaatt tttaattcca 18841 gattttgtat ggtcttacag attttatttc ctgaccttgc acctttgcag ataatgcagt 18901 acttttcaca aaaaacaggt ggattttttt tatcagccaa tataaaccct ccttttggtt 18961 agccccattt ttataaagat aatgagttac tatattttaa tatttgtctt aatgtttcaa 19021 aaaatttttg gagcggtttt atataaaaat tttaatagtt aatttagtct atgtcggttc 19081 ttgaaacatt ttttaatcgt gtgataccat ctatttcatc gataatgtct gctacagcat 19141 caggtacaag gtgtctccag tcattatcct caatcatctt tttccgaatt cttgtgcctg 19201 aatattgttc tctctggtac atgggtgact gttttacagg tattcctgcc tcttcaaaca 19261 gttgtattac cagtgggttg tttgaatata ccacatcaaa taaaggagtc cttgaaagta 19321 catgagatac ccataatgag ttctgctgga tatcttcgat aggaagagca taatttggaa 19381 ctttttcctt ttcaagagcg ttacgaatca tcatcactct ttcaccggct gtgaaaggat 19441 cagatggact atgacttttc tgggcactac ctattcctat aactacttca tcgacttcat 19501 cggcgattcg gttgataata gaattatgcc ccagatggta gggctggaat cgtccgatat 19561 aaaatgctct tttcctgtgc atagttgaaa attgtaaaat aagttatttt attccacctg 19621 cttcaaacga gaatttttca caggcttcca gataatgtgg ttcatttttc tcgtgtttca 19681 tattgagcag ttttttgata aggtccattc caggttctgg gttctccatt atctccaggt 19741 ctttgctggc ttttttgaag tacttttctc ctatatcggt gcgtataagt acactattcc 19801 agccatcagg ggcacctact gaacctatgg atatgtctgc atggactgcg gtatagtcac 19861 agcagttatg acacgggttt ctggcgtatt ctgctacagt agggattttt acactgtgtc 19921 cttcaccgtc ttttgtatat gcccagaatt ttcctttggc aaagtccatt ttaacgactt 19981 gttctatatc aagcccgaga acctttggta ttatatcatt taacatggtt tcatgatgga 20041 aactttccat acagaacaat cctattatga cggcgatttt atcgtttatg ttttcaaata 20101 tcagacgagc accatgagcc tgacagggta cacctacaac agcaatcctg tcatagtctt 20161 taaatggttc tctaagggca gaaattactg aatcataggt atattttgta cctgcggttt 20221 gatctacctg tgatggttct gtcattaaca ccagttcggt ttcccagttt tcatttctgg 20281 ttatgcctac aacacaatca atttcaccct tgtccagcag ggattttaat atagcagatg 20341 tgactccacc gtcctgcccg ggtatgctac ttctggctcc gaagaactgc ttgacattgt 20401 acagttcatc ttctacatat ccgtgaatca ccgggcatac attaccacaa gcgtaacaat 20461 cttcacatac cgaaggtgca gctccttttt catacagttc cagattattc gggtcacgta 20521 tctgtgcttt tttatcaatt gttatagccc cgacggggca tacggcagcg catgccccac 20581 aggctgtaca tacatcgttt tcaataacat ccaatatttt tgggtgcaat cattttcctc 20641 cgataatttc ctttcctatg agtttaatgg ctttctcttt tttgggaccg attggagagc 20701 ctacaacaat ctgtgtcaca cctgtattaa acaattcatc cactctctgt ttgcagtctt 20761 caggtgtacc acatactgaa aaagcattta ccatatcgtc ggtgaccata tctcccatca 20821 atgatttgaa atcacctttg gatattgcgt cactgatgtt tttcttggct tctgggtcga 20881 taccatggcg ttcaagtacc acatctggtg agcctgctac aataaatgca acaactactt 20941 tggcttcctg ttttgctttt tcagcatctt tatcaatcga gaagcatgtg taggctgcga 21001 tatcaatatc attcatatct ctaccagcgt tttccgcgcc ttctttaatt ttgtcaagag 21061 cgacgtcgaa atctcttgga tgggatccat taatcagtat tccatctgca acttctcctg 21121 cgagctgtag catttttgga ccctgggcac ccaagtatat ggggatgtct ccagtcttaa 21181 atgccatttt tgctccgccg actttgacca tctctccatc aagagataca ttttctcctg 21241 cgaaatatcc tctaagggcg gttacagatt ctttggttgt tgttaatggt ttttcccatg 21301 atatacccat tgaatcaaag gttgctttat ctcctggacc aattccaaga attgctctgc 21361 caccagatat ttcgtttata gcacctatac ttgatgcggt gattcctata tttctggtat 21421 acggatttgt aacaccagta cccagtttga tgctgttggt attattggca agtactgcca 21481 atgtagtata tacatcgcgg ttgttgaagt ggtctgtcac ccatacatta tcaaatccgc 21541 tctgttctgc taattttgca taatgagcga ttttaagtac agggtcactt ggtacaaatt 21601 ctattccgaa tgtcaattta gctcctccta tgttaaaata tatcaatatt gaggatatta 21661 tacatcttta tatctttatt ggttttacta ttttcctata atctgttttc taattaataa 21721 atacaaccct tattataata cgtactgtat ataaaaagtc ttttagtaat taaatcaatt 21781 atatatgaat gatatggtta cgtcattgta attgataaac ttagtaacat tagataacta 21841 attttattat cagttacatt cgtgagatat actcaccggg tgtaacgcta caccctctat 21901 cccatctaaa tcagggattg cttttttcat aatattatag gcaccatttt tctgtgttga 21961 ggatgtccta cttcgggtat ctggaaaaag ttttcataag attttgctaa ccttatcgcc 22021 acgtttttca gaactgaaga ataaacagtt ttcaaaaatg gtttttcttc ttttaaacgt 22081 ggaacctggt ttctcaagtt gtatttattg gtgagtttgt tcctactacc attatactta 22141 tagtcatatt cgaccatgtc gtaaagataa ttatataacc agttacatat cttcgattaa 22201 ccatcgagga tattctcatc ttcaccggag aaataagtgt ctaatattat acaaatttgt 22261 tgtataattt gggaactgtt ttattcccaa atcccagaga atttgaaagt taattaataa 22321 ttgaccaata tacatatatg ttggcagcag caaactaatt gatagttgta ggaggtgatt 22381 aattggcagt atcaagtgtt ggcgaaaaat atgtgtgtga aatatgcggc aatgaagtag 22441 aagtcactgt agttggtggc ggagtactgg tatgttgcgg agaagaaatg gaactggttg 22501 aataaatata aatcattggt atacatatac tgtttaattg ataaataaaa aacaaaggaa 22561 gattctaatg ttatgttatg actgtgctca gcaaggaaaa gatgtcgata caataggtat 22621 ctgtatactc tgtggaagag gcatctgtaa agaacattcg gtacgggaag accttcctgt 22681 tatgaaaggc gaatatgacg tggaattgga gtgtggaatg ggtgttgaat gtagtacaaa 22741 ggatatgcag catttacctc agatgctttg tccaacatgt cataaagtag tcaaggagaa 22801 ctattaaccg gagtgatttt tatgatgaaa tgttatgatt gtatgaatga aggtgtagat 22861 aaagaatcta caggtacctg tactttctgt ggtaaaggta tttgttctac acataccaaa 22921 aaattagaac ttcccgtatc tgttggaaca tacccaaatt ttaaaaggtt gccagaaccg 22981 cttccaaaat ttgtatgcaa tgaatgtgct gataatatca taactgatag ttttgattaa 23041 atgattgata aaggggagga tataaaatga cagatgaaaa agaagaacat cttgaaccag 23101 atgacttatt aaaagaaatg ggcgaaaaga taggatatac accacatata ctggagatac 23161 ttggtgaact tgatcctgac catctcacaa gatataacgc ctgcaacaaa aggattttat 23221 cagatggcga gataccatca aaatataaag tccttatggc acttgcagta gttgcatcca 23281 aacaatgtga aagatgcgcc cagacacaga tgataaatgc cattaatcac ggtgcaacca 23341 aagaagaaat catggaaacc atggatgtaa tagggataac ttcgggtgct cctgctgtag 23401 ctgcctgtag ggacgcactg aaattactac agaaagaaac agaataa //