LOCUS NC_014169:6 18347 bp DNA linear BCT 03-SEP-2013 DEFINITION Bifidobacterium longum subsp. longum JDM301 chromosome, complete ACCESSION NC_014169 SOURCE Bifidobacterium longum subsp. longum JDM301 chromosome, complete COMMENT locus start: 1442435; locus end: 1460781 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.501424; n0_4mer:D = 29.602383; n0_4mer:PS = 32.153734 FEATURES Location/Qualifiers source 1..18347 /organism="Bifidobacterium longum subsp. longum JDM301 chromosome, complete" gene complement(1..840) /gene="" /locus_tag="" /db_xref="1442435..1443274" CDS complement(1..840) /gene="" /product="cobyrinic acid a,c-diamide synthase" /translation="MPTDLLGREYETFPAPGPLQQHGPARVIAMCNQKGGVGKTTSSI NIAGALAQYGRRVLIVDFDPQGAATVGLGVNANTVENTIYTALFDISVDPHDVVQHTA FENIDVIPANIDLSAAEVQLVTEVGREQILNSVLRKLKSEYDLIIVDCQPSLGLLTVN ALAAADGVIIPVAAEFFALRGVALLMQSIEKVQSRINPALEVDGVLITMYTKTLHCEE VCQRVYEAFSEKVFHTFISRSIKLPDSTVAAAPVVVYAPEHKTSKEYREVARELIARG IVA" gene complement(1088..2014) /gene="" /locus_tag="" /db_xref="1443522..1444448" CDS complement(1088..2014) /gene="" /product="tyrosine recombinase XerD" /translation="MTNGFTRLTEQFLIHIGVERGLATATVTAYESDIAKYIDWLETR GIHEPDAITKQDVEDYIAALDQAGESARSKARRLASIHEFHRFALGQHAVTADVSAAV KAPKGASTLPDVLTVDEVTRLLDTAAVGGSTDPVVLRDKALLEFMYATGCRVSEATGA NLDDIDLDEHIARLMGKGSKQRLVPLGSYACRAITAYLNAGRGELERRSSAKIPERRA LFLNKRGKRISRQSVWEIVKATGERAGITKPLHPHTLRHSFATHLIQGGADVRTVQEL LGHASVTTTQIYTHVSPETLIETYLTAHPRAR" gene complement(2128..2511) /gene="rplT" /locus_tag="rplT" /db_xref="1444562..1444945" CDS complement(2128..2511) /gene="rplT" /product="50S ribosomal protein L20" /translation="MARVKRAVNAHKKRRVVLERASGYRGQRSRLYRKAKEQLLHSFN YNFRDRKARKGDFRKLWIQRINAAVRAEGITYNRFIQGLRLAGIELDRRALAEIAVSD PNTFKTIVDAAKAALPEDVNAPVEA" gene complement(2564..2758) /gene="" /locus_tag="" /db_xref="1444998..1445192" CDS complement(2564..2758) /gene="" /product="50S ribosomal protein L35" /translation="MPKMKTNSAASKRAKITGTGKVKHVGSAMRHNLEHKSARKRREL SADDVLRGGQAKKLHQLLQK" gene complement(2739..3134) /gene="" /locus_tag="" /db_xref="1445173..1445568" CDS complement(2739..3134) /gene="" /product="initiation factor 3" /translation="VTRFLNGGDKVKVTIMLRGREISRPIGGVELLQRLADDVEEYGT VESKPKQEGRNIIMTLAPKGKKVHTQSEQRRRGTESRAERQARQAARLAAKQESQAQA AADAQSAISQKTSDKKQTSKEGSNAEDEN" gene 3772..4497 /gene="" /locus_tag="" /db_xref="1446206..1446931" CDS 3772..4497 /gene="" /product="thiamine pyrophosphokinase" /translation="MTQVCVIFGAGEYYAGTPVVPAGAYVVAADGGLDHTRELGIVPD VVVGDFDSLEGRPPRTDVRTIALPALKDDPDMLSALKVGWSAGCREFHVYGGLGGRID HTISGIQLMALLARHGASGYLYGDGLIVTAITDGRLSFPAHPVPEDGRMVSAFSHSDV SLGVNEPGLKYELKNGTLTNTVVQGVSNEFRDGVDAAISVEHGTLIVTFPIEVALPQV SRFHEFGGDIGELDTAVSKLLVR" gene complement(4557..4712) /gene="" /locus_tag="" /db_xref="1446991..1447146" CDS complement(4557..4712) /gene="" /product="hypothetical protein" /translation="LARFGTPGHCLPTVATVMPTLYTWQRFSVRFGQKCRIFCERSQF GLPATDM" gene 4737..5795 /gene="" /locus_tag="" /db_xref="1447171..1448229" CDS 4737..5795 /gene="" /product="glyceraldehyde-3-phosphate dehydrogenase" /translation="MTVKIGINGFGRIGRLAFRRIFELQARGGQAGDIEVAAINDLTT PATLAYLLKYDSTHGTFRHDDGTPVDVKATEDSIIVDGKEYKVYAEKDANNIPWVKND GVEYVLECTGFYTSAEKSQAHINAGAKKVLISAPAKDDTTPTVVFGVNHDILKASDVI VSAGSCTTNSMAAMVKLLDEKFGIKAGFMTTIHAYTGTQMLLDGPRGTKTGRNLRAAA INTIAHSTGAAKAIGKVVPSVNGKLQGHAQRVQVPDGSVTELTTVLNTETTADEINEA FKAAFSDTEYYGYNDEGIVSSDILGDTHGGVFDPTQTDVNTVDGVTMARTVSFYDNEY GFTSNMIRTLLYFAEISE" gene 5889..6398 /gene="" /locus_tag="" /db_xref="1448323..1448832" CDS 5889..6398 /gene="" /product="YbaK/EbsC protein" /translation="MAKKSKHDKGAGSTPATVQLEKAGVEFHVYEYEHSNDHMDDGYG VEAATKLGFDEHQVFKTLMADTGSERVVGVVPVSGHMDLKALAAAVGAKKASMADPKV AMRESGYVVGGISPLGQKTRHKTVLDESAMQFDQILVSGGKRGLSVGVNPQDLLKVLN AIAAPIGTW" gene 8248..9393 /gene="" /locus_tag="" /db_xref="1450682..1451827" CDS 8248..9393 /gene="" /product="hypothetical protein" /translation="MYFTSGSDRAFEQLMQTRPGADHFDSGEAGAPEDCGTCRFYRPH WKYQFCVYEECPYQPGKRTALDGAVKFQVKGVDDEMAVFRVEKNRGYTVMSNHHLRNK DLSLKAKGLLSQMLSLPEDWDFTLKGLSLINREQIDAIRAAVRELEQAGYIVRSRERD SQGRLRGADYIIYEQPQPVSDLPTLENPTLDNPTQEKPTQEKPTQLNKDRSSKEKSIT DGSNTDSIPILSPPSPLGEEAAAPPERKGTGAKSQSAVEIYREIIKDNIEYEHLCQYA KGIDRDMLDEIVDLLVETVCSARKTIRIAGDDYPAELVKSKLMKLNSSHIEFVFDCIS KNTTEIRNIKKYLLAVLFNAPSTINGYYTALVAHDMNTGSWGTPQNR" gene 9459..9707 /gene="" /locus_tag="" /db_xref="1451893..1452141" CDS 9459..9707 /gene="" /product="hypothetical protein" /translation="MELVTTRKEADPMKQGALIFDEQTDRYDIRFDLADYYGGLHCGE TFDVMVGGRWRPTRIEMAENWYLVGIHADDLSGLRVRI" gene 9750..10226 /gene="" /locus_tag="" /db_xref="1452184..1452660" CDS 9750..10226 /gene="" /product="hypothetical protein" /translation="LQEEVDQKTIALAVKTGKLTAQVLQAAIQKYLAARQKGTGKARH GQQSLRQLKKDGSALSNIEITDANIGLFKPCAKKYDIDFTLRKDRTTHPPRYIVIFKS KQADNLEQAFKEFTAKKLKQQERPSIRKTLAVLKEKAAARSSQQAKEKIKERGLSR" gene 10235..12028 /gene="" /locus_tag="" /db_xref="1452669..1454462" CDS 10235..12028 /gene="" /product="hypothetical protein" /translation="MKKLIIANLPYLLFVYLFGKLGQTYRLAAGADLSEKLLHLADGF SLAFESAAPSFHLFDLAVGVAGAVALRLMVYCKSKNAKKYRRGVEYGSARWGGPKDIA PYIDPVFDNNILLTQTERLTMNNRPKDPKTARNKNVLVIGGSGSGKTRFFVKPNLMQC VSKDYPTSFVITDPKGSLIGEVGQLLVRCGYRVKVLNTINFSKSMRYNPFRYIHSEKD ILKLVNTLICNTKGEGEKSAEDFWIKSERLLYSALIGYIWYEAPDDEMNFTTLLEMIN ASEAREDDPEFQSPVDQMFERLEEKDPEHFAVRQYRKFLLSAGKTRSSILISCGARLA PFDIREVRELMEDDELELDTVGDQKTALFLIMSDTDTTFNFILAMVQSQLINLLCDRA DDKYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLKAIYKD AAEIISDNCDCTLFLSGRGKNAKEIAEVLGKETIDSYNQSENRGAQTSHGLNYQKLGK ELMSQDEIATMDGGKCILQVRGVRPFFSEKYDITRHPRYKYLSDADKKNTFDVDSYLS SLRRKKRRVVTEDEPFDLYDIELSDEDFAAE" gene complement(12912..14210) /gene="" /locus_tag="" /db_xref="1455346..1456644" CDS complement(12912..14210) /gene="" /product="integrase core domain-containing protein" /translation="MATKRQVTLRFRDEYVRASKKQKGVILDRMCETLGIGRSTARRL LAQAGQHGNGAVPAARERPCRYSDQSRQLLVRVWVLMDMPCGKYLKAMLPQWLPVLRD CGELDAYDGFTFSELMAMSASTIDRYLKPLRDAARPKGLAATRPAGELLRNSITIRKA SDELDGLPGNVEADTVAHCGPSLKGEFCRTLTVVDFATGWTENASARNNAYRNLSQAE AMIEQRPPFTIRSYDNDNGSEFINTDFITHLQQLDIQQTRSRPYRKNDQATVESRNNH VVRKHAFYYRYELAELDLLNELWQLVSVKVNLFTPSKKPVGRSSTRDGRPRRVYDQPT TPWERLKRFDEQDRADGGTGFILPERRDQIERLIAETNPAELVRRIHAIQDQLEDMAA PRTRRLEKRVGPDMAYLDRTLAKIAGVRPEDHNETPADTD" gene 15123..17042 /gene="" /locus_tag="" /db_xref="1457557..1459476" CDS 15123..17042 /gene="" /product="translation elongation factor G" /translation="MKIINIGILAHVDAGKTTLTESLLYASGAISEPGSVEKGTTRTD TMFLERQRGITIQAAVTSFQWHRCKVNIVDTPGHMDFLAEVYRSLAVLDGAILVISAK DGVQAQTRILFHALRKMNIPTVIFINKIDQAGVDLQSVVQSVRDKLSADIIIKQTVSL SPEIVLEENTDIEAWDAVIENNDKLLEKYIAGEPISREKLVREEQRRVQDASLFPVYY GSAKKGLGIQPLMDAVTGLFQPIGEQGSAALCGSVFKVEYTDCGQRRVYLRLYSGTLR LRDTVALAGREKLKITEMRIPSKGEIVRTDTAYPGEIVILPSDSVRLNDVLGDPTRLP RKRWREDPLPMLRTSIAPKTAAQRERLLDALTQLADTDPLLRCEVDSITHEIILSFLG RVQLEVVSALLSEKYKLETVVKEPTVIYMERPLKAASHTIHIEVPPNPFWASIGLSVT PLPLGSGVQYESRVSLGYLNQSFQNAVRDGIRYGLEQGLFGWNVTDCKICFEYGLYYS PVSTPADFRSLAPIVLEQALKESGTQLLEPYLSFTLYAPREYLSRAYHDAPKYCATIE TVQVKKDEVVFTGEIPARCIQAYRTDLAFYTNGQSVCLTELKGYQAAVGKPVIQPRRP NSRLDKVRYMFQKIM" gene complement(17085..18167) /gene="" /locus_tag="" /db_xref="1459519..1460601" CDS complement(17085..18167) /gene="" /product="integrase catalytic subunit" /translation="MRVAEIHLHVQRGRDAFVQGELASLVPGQRVPQELGQVLHFPDD GLLDVFGVVPVGQVQEDREPCRAFHERADRAFVGRAADQVAFPMTGYRPVLDFGGPLA DHDHGFAETGLARVRLPVRPALGAPAPQGLDDVLFQFAFGLDVDGLVDRLRAHMHSII IREIGAQTPRDLLGTPMRPQSCANVCEQAGHRMDLRGLGSSGPSALICWGRYGSYMPV AGFVLRTSSRLAVDAGRLSVRAIPRTLMPAFRQSAMLMRSSWLRYLELIFWGMSTVER YQSTDGFSFLPFDRVLPLRHTLPVRLDTPTARAACVKFMPTSRCSTYRRRRAAHISPC VAYSTPSNAHLPIRSSYRSIRCCNDH" gene 17088..18347 /gene="" /locus_tag="" /db_xref="1459522..1460781" CDS 17088..18347 /gene="" /product="Fis family transcriptional regulator" /translation="VIVATSDRPVGGSDGQVGVRGCGVRDAWRDVRGAATPVRRASRG GHELHAGRAGGGRVQTHRQGVAQRKDTIERQEREAIGGLVSFHRGHSPKDQFEVSEPG RAHQHRRLAEGRHERARDRAHAQSSRVDRQPRAGAQHESRDRHVRAVPAPADERGRPR RPKPAKIHTVPGLLAYIRAGLRAHWSPEQIAGRLRADFPDNDAMHVCAETIYQAIYVQ AKGELKKDVIKALRSGRAQRRPHGQTDSRKPRFREPMIMISERPAEVEDRAIPGHWEG DLICSAANKSAIGTLVERSTRFTILLHLPDRHDAKHVQQAVIRKMQYLPKLLRNSLTW DQGSELTLHKRISTTLDMQVYFRDPHSPWQRGTNENTNGLLRQYFPKGTDLSAYPEDH LDAVAEELNDRPRKTLGYRKPSEKIGL" ORIGIN 1 ttacgccacg atgccgcgag caatgagctc acgtgccacc tcacggtatt cctttgatgt 61 cttgtgctca ggtgcataga ccaccacggg cgcggcggca accgtggaat cgggcagttt 121 gatggagcgg gagatgaacg tgtggaacac cttttcgctg aacgcctcgt aaacgcgctg 181 gcagacctct tcgcagtgca gtgtcttggt gtacatggtg atgagcacgc catccacttc 241 caatgcggga ttgatgcggg actgcacttt ttcgatggac tgcataagca gggccacacc 301 gcgcaaggcg aagaattcgg cggccacggg aatgatcacg ccatcagctg cggcaagcgc 361 gttcacggtg agcaggccga gcgatggctg gcagtcgacg atgatgagat cgtattccga 421 cttgagcttg cgcagcacgc tgttcaggat ctgctctcgg cccacttcgg tgaccagttg 481 gacctcggcg gcggacaaat cgatgttcgc cggaatcaca tcgatgttct cgaatgcggt 541 gtgctgcacc acatcatgtg gatccacgga aatatcgaac agcgcggtgt aaatcgtgtt 601 ctccacggta ttcgcgttga cgcccagtcc cacagtggcg gcgccctgcg gatcgaaatc 661 gacgataagc acgcggcggc catactgggc caacgcaccg gcgatattga tggagctggt 721 ggtcttacct acgccgccct tctggttgca catggcaatg acgcgcgccg gaccgtgctg 781 ttgcagcggt ccgggtgcgg ggaaggtttc gtattcacgt ccaagcaaat cggtaggcat 841 actgtctacc ttatcaatat ccatgttccg gggtggtgta acgacatacg cttcgtccat 901 gggcagcgtg ccttgacgga atgcgccgtc ttgcccgtgg tcgccacgcc gatctgccat 961 gcctggacct ccgtcgaatc ctgatctcac ctgaccagcg tactcttatc cgttcgccaa 1021 tatcgccgca aacacgttgc ttcgacatat cgcggacaac ccgtctcatc acctcgccag 1081 acatcggtca tcgcgcccga ggatgggcgg tgagatacgt ttcgatcagg gtttccggac 1141 ttacatgcgt gtagatctgc gtggtggtca cgctggcgtg cccaagcagt tcctgcacgg 1201 tgcgcacgtc cgcgccacct tgaatcaggt gcgtggcgaa ggaatggcgc agggtgtgcg 1261 gatggagtgg tttggtgatg ccggcccgct ccccggttgc tttgacgatt tcccataccg 1321 attgccgcga gatgcgcttg ccacgtttgt tgagaaacag tgcgcgtctc tcgggaatct 1381 tggcgctgga gcgccgttcc agctcgccac gccccgcatt gaggtatgcg gtgatggccc 1441 ggcatgcgta gctgcccaat ggcacaagcc gctgcttgga gcccttgccc atgagtcgcg 1501 cgatgtgctc gtccaggtcg atgtcgtcca gattcgcgcc ggtggcttcc gagacgcggc 1561 agccggtggc gtacatgaat tcgagcaggg ccttgtcccg caataccacc ggatcggttg 1621 atccgccgac tgccgccgtg tcgagcagac gggttacctc gtccacggtg agtacgtcag 1681 gcagggtgct ggcacctttg ggtgccttga ctgcggcaga aacgtcggca gtcaccgcgt 1741 gctgaccgag cgcgaagcga tggaattcgt ggatcgaggc cagtcttcgg gctttggagc 1801 gggcggactc ccccgcctgg tcaagggcgg cgatgtagtc ttcgacgtct tgtttggtta 1861 tggcgtccgg ttcgtggatg ccgcgggttt cgagccaatc aatgtatttg gcgatgtcgg 1921 attcgtaggc ggtgacggtg gccgtggcga gtcctcgctc cacgccgatg tggatgagga 1981 actgctcggt gagtctggtg aatccgttgg tcatgagttt gttctctccc cacccgctgc 2041 gcgggagccc cctcgtcaga gggggctaat aataggaaac cccgctcgga agcggggttt 2101 ctagtgtgaa gtcacgactt caagcaatca ggcctcaacc ggagcgttga cgtcctcagg 2161 cagggcggcc ttggcggcgt ccacgatggt cttgaaggtg ttcgggtcgg agacggcgat 2221 ctcagccaga gcgcgacgat ccagctcgat gccggcgaga cgcaggccct ggatgaagcg 2281 gttgtaggtg atgccctcag cgcggacggc agcgttgatg cgctggatcc acagcttgcg 2341 gaaatcgccc ttgcgagcct tgcggtcgcg gaagttgtag ttaaaggagt gcagcagctg 2401 ttccttggcc ttgcggtaca ggcgggagcg ctggccacgg tagccggaag ccctctcgag 2461 aacaacgcga cgcttcttgt gggcgttcac tgcgcgcttg acacgtgcca taatctattc 2521 ctcagctttc taaagtctta ttatttccgg gtaagcccta tgctcacttc tgcagaagct 2581 ggtgcagctt cttggcctgg ccgccgcgca gcacatcgtc ggcggacagt tcacggcgct 2641 tgcgagcgga cttgtgctcg aggttgtggc gcatggcgga accgacatgc ttcaccttgc 2701 cggtgccggt gatcttggcg cgcttggaag cggcggaatt agttttcatc ttcggcattg 2761 ctgccctcct tgctggtttg cttcttgtcg gaagtcttct gagaaatcgc ggactgcgcg 2821 tcggccgcgg cctgagcctg agactcctgc ttggccgcga gacgagccgc ctggcgagcc 2881 tgacgctcgg cgcgggactc ggtgccacga cgacgctgct cggactgggt gtggaccttc 2941 ttgcccttcg gcgcaagggt catgatgatg ttgcggccct cctgcttcgg cttggactcg 3001 acggtgccgt attcctcgac atcgtcggcc aaacgctgca gcagttccac gccaccaatc 3061 gggcgggaga tctcacgacc gcgcaacatg atggtgacct tgaccttgtc gcctccgtta 3121 aggaaacggg tcacatggcc cttcttcacg tcgaaatcgt ggtcgtcgat cttcaggcgg 3181 aaacgaatct ccttgatttc cgcggtgctc tggttgcggc gagcctcacg agccttgatc 3241 ttctcgttgt acttgaactt gccgtaatca atgagcttgg cgaccggagg cttcgcgttc 3301 ggggccacct cgacgagatc gaggtttgcc tccttggcca ggttcagcgc gacggaagtc 3361 gcgatgacgc ccacctgctc gcccttcggg ccgatcaggc gtacctgcgg gacgcgaatc 3421 tcgtcgttaa tacgtggttc gtcgctgatg atgactccaa tcctctactt taattccgtg 3481 gcgaggtcct ttgctggagt cctgttcaat gctttgggtt catggcaagc caaagtcagc 3541 gccaatatgc gctcagcttc tgcaggcgca tatcagttct ttgcgtcatt cctgattgcg 3601 cgttgcatat cgcaatcgct aggctgtttg ccttgaaccc gaggccttga aaggcttcca 3661 ggtggggttg ccccgctttc ttgatttctc aagccaagta ggaattctac cacacgcccg 3721 gacattcgcg gcacgtgtgt cggtgggtgg ataccggcta cagtgggcat aatgactcag 3781 gtatgcgtga tttttggtgc gggcgaatac tatgcgggca cgcccgtggt gccggccggc 3841 gcgtatgtgg tggcggccga tggcgggctc gaccatacgc gcgagttggg catcgtgccc 3901 gatgtggtgg tgggcgattt cgattcgctg gagggccggc cgcctcgcac cgatgtgcgc 3961 accatcgcgc tgcccgcgtt gaaggacgac ccggacatgc tttccgcgct gaaggtcggt 4021 tggtcggcgg gttgccgcga attccatgtc tatggcggtt tgggcggccg cattgaccat 4081 acgatttccg gcattcaact gatggcatta ttggcccggc atggggcaag cgggtacctg 4141 tatggtgacg ggctcatcgt cacggccatc accgatggca ggctttcgtt ccccgcgcat 4201 ccggtgcccg aggacggccg tatggtgtcg gcgttctccc actccgatgt ttcgcttggc 4261 gtgaacgaac cggggctgaa atacgagctc aagaacggca cgctgaccaa tacggtggtg 4321 caaggcgtca gcaacgagtt ccgcgacggc gtggacgcgg ccatcagcgt ggaacacggc 4381 acactgatcg tcactttccc catcgaggtg gcattgcctc aggtgagccg atttcacgaa 4441 tttggcggcg atatcggcga gctggacacc gcagtgtcca agctgctggt tcgctgactc 4501 gcgtatcgtg cgcttgctcg tgatgattca agacattcct ccaaaggaga ggaaaatcac 4561 atgtcggttg cgggcaatcc gaattgtgag cgctcacaaa aaatacggca tttttgccca 4621 aaacgcacgc tgaaacgttg ccatgtgtac agagtcggca ttacagtagc aactgttggt 4681 aaacaatggc ccggtgtgcc aaagcgcgcc aaggccaccc tacaagggag aattacatga 4741 cagttaagat tggtatcaac ggcttcggtc gcattggtcg tctcgccttc cgtcgcatct 4801 tcgagctgca ggctcgcggc ggccaggctg gtgacattga agttgccgcc atcaacgatc 4861 tgaccacccc ggctaccctg gcttacctgc tgaagtacga cagcacccac ggcaccttcc 4921 gtcatgacga tggcactccg gttgacgtca aggccaccga agactccatc atcgtcgacg 4981 gcaaggaata caaggtctac gccgagaagg acgccaacaa cattccgtgg gtcaagaacg 5041 acggtgtcga gtacgtgctc gagtgcaccg gcttctacac ctccgctgag aagtcccagg 5101 ctcacatcaa cgctggcgcc aagaaggtcc tgatctccgc cccggccaag gatgacacca 5161 ccccgaccgt tgtgttcggc gtgaaccacg acatcctcaa ggcttccgac gtgatcgtct 5221 ccgccggctc ctgcaccacc aactccatgg ccgccatggt caagctgctg gacgagaagt 5281 tcggcatcaa ggccggcttc atgaccacca tccacgccta caccggcacc cagatgctgc 5341 tcgatggccc gcgtggcacc aagaccggcc gcaacctgcg cgccgccgcc atcaacacca 5401 tcgcccactc caccggcgcc gccaaggcca tcggcaaggt cgtcccgtcc gtgaacggca 5461 agctgcaggg ccacgcccag cgcgtccagg tcccggacgg ctccgtcacc gagctgacca 5521 ccgtgctgaa caccgagacc accgccgacg agatcaacga agccttcaag gctgccttct 5581 ccgacaccga gtactacggc tacaacgatg agggcatcgt ctcctccgac attctcggcg 5641 acacccacgg cggcgtcttc gacccgaccc agaccgacgt caacaccgtt gacggcgtga 5701 ccatggctcg caccgtctcc ttctacgaca acgagtacgg cttcacctcc aacatgatcc 5761 gcaccctgct gtacttcgct gagatctccg agtgaaccac tgcggtctag gccgctacgg 5821 ttcgtttgag aactaagctg tgagaccccc gccttgtgcg ggggtctctt cgtagtagaa 5881 cggtaatcat ggcaaagaaa agcaagcatg ataagggcgc gggttccact ccggcgacag 5941 tccaactgga gaaggcgggc gtggaattcc acgtatacga atacgagcac tccaacgacc 6001 atatggatga cggctacggc gtggaggcgg ccaccaagct cggcttcgac gaacatcagg 6061 tgttcaagac gttgatggcg gacaccggtt cggagcgagt ggtgggcgtg gtaccggtca 6121 gtggccatat ggatttgaag gccctggctg cggctgtagg tgccaagaag gcctctatgg 6181 ccgatcccaa ggtggcaatg cgcgaatccg gctatgtggt aggtggcatc tcgccgttgg 6241 gccagaagac acgtcataag actgtgttgg atgaaagcgc catgcaattc gaccagattc 6301 tggtctccgg cggtaaacga ggcctgtccg tgggggtgaa cccgcaggac ctgctgaagg 6361 tgctgaacgc cattgccgca ccaatcggca cgtggtaaat gaatcagctt tcagccacta 6421 cattttctcg gctattctct atatttcgtt gaaatctctt ctctcataca taaaattcga 6481 gactgacggt cgcataaata acgtaaccat cagtctcaat tattgtactt tactaacccc 6541 gaatgtttca ctgcttttca agagtgaact cgtgatcgcc tccaacgtca aaagtcatgt 6601 cattattttc aattgaaact ctcacagtat ctcctgtatt aagttcgaca tcaaaccaat 6661 tatcttctgg agagccagaa acgaccttcc cattctgaat attaaccaat cctgcgccac 6721 cccacacttc gccgggaacg ctatctattg taacttcatc tccggttttt tgatcataat 6781 aaacgacatt agcggacaaa gtcccattct tatttatggt gaaggtataa tcacatgaca 6841 atgagtagaa ttgcatttct tttatgttgt ctccatgacc acaatcctcc agcatccctt 6901 cgtatgtgcc atatggatta ctacccaatg gaaccgaaca tgcggaaata agagttccaa 6961 taatcaaagc caatacaaca acagaataat atttattttt tctattcatt ctacttcctt 7021 tattcgttta ttctgttata aaataattac tgtatgtcat atgtaatcgt ggactcccct 7081 gttccagctg cttgtatatg gcatactgta aaacctttat tgcgcgtaca tcgagcctgt 7141 gctacatcag tcaaaggtga gaactctata ttccaaatcg aactgccata gatacctgaa 7201 tattcatcaa tttgattttg caatccaagc ccttccagat atcctcgcaa tcgttcacca 7261 gcagtccctg aatccaagcc cggctcataa ccgacgtccc acgcaataca ccccagcccc 7321 atcgtgactg cataattatg agattctaaa tcatagccgc catacatcct catacgatca 7381 taatttggtc ctttaaattg cagatatgca atactgttat catctctatc tcggtcaatt 7441 ttaaaatatg catcagcgct gtttccacta aatacagaat tgtattgatc agagcaatga 7501 aatatacttt cgaaattgat ttctctggtc actgattgcg gattatcgga ggcatcattg 7561 tcttctttgg aatcatcttt gtccgcatca ttatcctcgc tcacatttgt ttcatcagca 7621 ggctctattg ccttacctat ttcttcattg cgcttttttc catcgttgag catagtctca 7681 tttttttttg caaatataac gctaccaaga acaaggagaa caaccaccag tatgataaat 7741 aatgctttct ttttcatagc tggctcacac ctttactcca tattccaagt aactgcgcta 7801 cttaagatag aatcaaccgt gagatcatca atgatggtgt ttagacgcac taagacagga 7861 cgacttttgt gataacgaat aatcagacga ccataaaagg gccgaagaga tgaccactct 7921 tcacccatgt aggcagggcc aggaacagat cctttaggag caagctccct gacaatcgtt 7981 ttgattgtta gatcaacaac tctgattatc tccaaaaagc ccggaaatac gggcatttca 8041 cgggatataa gaactgaatt tactaccgat ttactacttt cggattgagc tttgacacgc 8101 ttcttcctcc cgtgaagccc accgcccaaa tagtgacaca tcgaaaattg aatacgacac 8161 cgcagacagc ggcgttctct tttccccttt ggggagatca ggacgccgct ttttttgcgc 8221 ccaaaaccag aaaggaggcg accgcctatg tactttactt ccggcagcga ccgggccttt 8281 gaacagctca tgcagacgag gccgggcgca gatcattttg acagcggcga ggccggagcg 8341 ccggaggact gcggcacctg ccgtttctac cgcccgcact ggaagtacca gttttgtgtg 8401 tatgaggaat gtccctacca gccgggcaag cgcaccgccc ttgacggcgc ggtgaaattt 8461 caagtgaaag gagtggacga cgagatggca gtttttcgag tggagaaaaa ccggggctac 8521 acggtgatgt ctaaccacca cctgcggaac aaggacttgt ccctgaaagc caagggcctg 8581 ctgtcgcaaa tgctgtcctt gccggaggat tgggacttta cgctgaaagg cttgtccctt 8641 atcaaccggg aacagatcga cgcgatccgg gcggctgtcc gggagctgga acaggcgggc 8701 tatatcgtgc gttcccgtga gcgtgacagc caaggccgcc tgcgcggagc ggattacatc 8761 atttacgaac agccccagcc tgtgtcggat ttacctacat tggaaaatcc aacattggat 8821 aatccaacgc aggaaaagcc tacgcaggaa aaaccaacgc aattaaataa agatagatca 8881 agtaaagaga aatcaattac ggatggatca aataccgatt ccattcctat cctttcccct 8941 ccctctcctt tgggggaaga agcggctgcg ccgccggaac ggaaaggaac gggagcgaaa 9001 tcacagagcg ccgtagagat ttatcgggag atcatcaagg acaacatcga gtatgaacac 9061 ctttgccagt acgccaaggg gattgaccgg gatatgctgg acgagatcgt ggacttgctg 9121 gtggaaaccg tatgcagcgc ccgaaagacc atccgcattg ccggggacga ttaccccgcc 9181 gagctggtga aatccaagct gatgaagctg aacagttctc acattgagtt tgtctttgac 9241 tgtatcagca aaaacaccac ggaaatacgg aacatcaaaa aatacctgct ggcggttctg 9301 ttcaacgccc caagcaccat caacggctat tacacggcgc tggtggccca cgacatgaac 9361 acaggcagtt ggggaacccc gcaaaatcgg tgattttgtg gggagaggag gaacagcgaa 9421 atgagcgagc ttttcacgct tgcgtggaaa caagcgatat ggagcttgtg acgacgagaa 9481 aggaggccga ccctatgaaa cagggtgctt tgatttttga cgagcagaca gaccgctacg 9541 acatccgctt tgaccttgcg gactattacg gcggcctgca ctgcggagaa acttttgatg 9601 tgatggtggg cggcagatgg aggccgaccc gcattgaaat ggccgagaac tggtatctgg 9661 tgggaatcca tgccgacgac ctctccggcc tgcgggtgcg gatttaagcc atccgcctgc 9721 ctgctgactt tccaaaggag ggatagcagt tgcaggaaga agtagaccag aaaaccatag 9781 cgttagcggt taagacgggc aagctcaccg cccaagtgct gcaagcggcc atccaaaaat 9841 atctggccgc ccggcagaaa gggacgggca aggcccgtca cggacagcag agcttacggc 9901 agctcaaaaa ggacggttcc gccctgtcca acattgagat caccgacgcc aacattggct 9961 tatttaagcc ctgcgccaag aaatacgaca ttgattttac cctgcggaaa gaccgcacta 10021 cccatccgcc ccggtatatc gtgatcttca aatccaagca ggcggacaat ctggaacagg 10081 cgtttaagga gtttacggcc aagaagctca aacagcagga acgcccctcc atccgaaaga 10141 cccttgccgt cctgaaagaa aaggcagcgg ccagaagtag ccagcaggcc aaggagaaaa 10201 tcaaggaaag ggggctgtca cgatgaagcc ggaaatgaaa aagctgataa tcgctaacct 10261 gccctacctg ctgtttgttt acctgttcgg caagctggga cagacctacc ggctggcggc 10321 tggggcggac ttgtcggaaa agctattgca ccttgcggac ggcttttccc ttgcctttga 10381 aagtgccgcc cccagcttcc acctgttcga tctggcggtg ggcgtggccg gtgcagtggc 10441 actgcggctg atggtgtact gcaagagcaa gaacgccaag aaataccgcc ggggcgtcga 10501 gtacggcagc gcccgttggg gaggccccaa agatatagcc ccgtacatcg acccggtgtt 10561 tgacaacaac atcctcctga cccagacgga acgcctcacc atgaacaacc ggcccaaaga 10621 ccccaagacc gcccggaaca aaaatgtgct ggtgatcggc ggttccggca gcggcaagac 10681 ccggttcttt gtgaagccca acctcatgca gtgcgtgtcc aaggactacc caacctcatt 10741 cgtgattact gacccgaaag gaagtctgat cggcgaggtg ggccagctcc ttgtgcggtg 10801 cggctaccgg gtaaaagtgc tgaataccat taacttttcc aagagtatgc gctacaaccc 10861 gtttcgctac atccattcgg aaaaggacat tttgaagctg gtaaacacgc tgatctgcaa 10921 caccaagggc gagggcgaaa agagcgccga ggatttttgg atcaaatcgg aacgcctgct 10981 gtattcggcc ctcattggct atatctggta cgaagcgccg gacgatgaaa tgaatttcac 11041 cacgctgctt gaaatgataa acgccagcga agcccgcgag gacgacccgg aatttcaatc 11101 cccggtagac cagatgtttg aacggctgga agaaaaagac ccggaacact ttgcggtgcg 11161 ccagtaccgt aaattcctgc tgtcggcggg caagacccgc agctccatct tgataagctg 11221 cggagccaga ttagcgccct ttgacatccg ggaagtgcgg gagctgatgg aggacgacga 11281 actggaactt gacaccgtcg gggatcaaaa aacagccctg ttcctgatta tgtcggacac 11341 ggacacgacc tttaatttca ttttggcaat ggtgcaaagc cagcttatca atcttttgtg 11401 tgaccgggcc gatgacaaat acggcgggcg gctgcccgtc catgtgcggc tgattctgga 11461 cgagtttgcc aacatcggcc agattccaaa cttcgacaag ctgatcgcca ccatccgaag 11521 ccgggaaatc tcggcttcta ttattttgca gagccagtcg cagctaaagg ccatttacaa 11581 ggacgcggcg gaaatcattt ccgacaactg cgactgtacg ctgttcctta gtggcagggg 11641 caagaacgcc aaggagattg cggaggtgct gggcaaggaa accattgaca gctacaacca 11701 aagcgagaac cggggcgcgc agacctccca cggactgaac taccaaaaac tcggaaagga 11761 gctgatgagc caagacgaaa ttgcaacgat ggacggaggc aagtgtattt tgcaggtgcg 11821 cggcgtaagg ccatttttca gtgagaaata cgacatcacc cgccaccccc gctataaata 11881 cctctcggac gctgacaaaa agaacacctt tgatgtggac agctacctgt cgtccctgcg 11941 ccggaaaaag cggcgcgtgg taacagagga cgaacccttt gacctctacg acattgagct 12001 gtcggatgaa gattttgccg cagaataaag cggccataga gaaaggagcg tgaccgatgg 12061 gacactcgga cgaatggaca tttgcggatt atttcaggta tgagaaagaa atctaccggg 12121 cgatcatttc cgctgcggtg ctgtgccagt ggatcgcgga acatgatacc ccgcccacag 12181 acggggaagc cgaagaactt gcaagggaaa tagaccgcag actgtgtgaa gcatggggcg 12241 aaattttttc gctggctgtg ctggaatggc gggacggcca gtaactccgg gccgtctgcg 12301 gattgtgagg ctgccgctgt gaacggcggc tttttttgca cccaaacacc atcacaatct 12361 gaatttatgg aggtaaattt atggaatttt tcaatagtgc agttgatact ttgcagacca 12421 tcgttgtggg cctcggtgga gcgctttgcg tatggggcgg cgtcaatctt ttggagggat 12481 acggggcgga caacccggca agcaatgctc atgtacggta aagaagcaag caaccgaaaa 12541 caatagatag accgccagca ctacactatt ccgaaccaaa gaccaaaaga taagcatttt 12601 gagaaaatct aaacttttgg attttcctac aatgccgact acggcggaat ccctcccact 12661 ccttatatat ttctttctgt atacattgaa tttgtattta gtaaaatgca gacaacacca 12721 cggatcggct tttggctgga caattccaac caaacaccgc agcagacagt agaaaccatt 12781 ctgaacgtta ggaagccggt atgattgtta catataaggg gaagaaaaat ttcttttaga 12841 taccgaggtg cctcatttga aagtgagcgc gaaaccggga gtggtgcctc actggaagtg 12901 agcgcgaaat cctagtcggt gtcggctggt gtttcgttgt ggtcttccgg tcggacgccc 12961 gcgatcttgg cgagtgtcct gtccaagtat gccatgtcgg ggccgacgcg tttctcgagg 13021 cgtcgggttc gtggagcggc catgtcctcg agctggtcct ggatggcgtg gatgcggcgg 13081 acgagctcgg ccgggtttgt ctcggcgatc agacgttcga tctggtcgcg tcgctcgggc 13141 aggatgaacc cggtgccgcc gtcggcccgg tcctgctcgt cgaatcgttt gagtctctcc 13201 catggggtcg tgggctggtc gtagacgcgc cggggtcgtc cgtcgcgggt gctggagcgt 13261 cccacgggtt tcttggacgg ggtgaacagg ttgaccttga cgctcacgag ctgccacagc 13321 tcgttcaaca ggtcgagttc ggcgagttcg taccggtagt agaacgcgtg tttgcgtacg 13381 acgtggttgt tgcgggattc gacggtggcc tggtcgttct tcctgtaggg gcggcttctg 13441 gtctgctgga tgtcgagctg ttggaggtgg gtgatgaagt ccgtgttgat gaactcgctg 13501 ccgttgtcgt tgtcgtagga gcggatcgtg aacgggggcc gctgctcgat catggcctcg 13561 gcctgggaga ggttgcggta cgcgttgttg cgggcggacg cgttctcggt ccatccggtg 13621 gcgaagtcga ccacggtcaa ggtgcggcag aactcgccct tgaggctggg gccgcagtgg 13681 gcgacggtgt cggcctccac gttgccgggc aggccgtcca gctcgtcgct ggctttcctg 13741 atcgtgatcg agttgcgcaa cagctcgccg gccggacgcg tagccgccaa acccttgggg 13801 cgggcggcgt cacgcagggg cttgaggtac cggtcaattg tggaagcgct catcgccatg 13861 agctcgctga acgtgaaccc gtcataggcg tccagctccc cgcaatcgcg caacacgggc 13921 agccactgcg gcagcatcgc cttcaaatac ttgccacacg gcatatccat caacacccac 13981 acccgtacca gcagctgtcg cgactggtcc gaataccggc acggccgctc ccgcgccgcc 14041 ggcaccgcgc cgttcccatg ctgcccggcc tgggcgagca ggcgcctggc cgtgctcctg 14101 cctatcccca gtgtctcgca catcctgtcc aggatgacgc ccttctgctt cttcgacgcc 14161 ctcacgtact cgtccctgaa cctgagggtg acctgccgct tcgtcgccat gctgatcctg 14221 tcttccatac gacaagccaa acagaccaac ccggtttcgc gctcactcca ggtgaggcac 14281 cactacccat ttcgcgctca aaaaacgtga ggcacgtcgg atacttgttt tcctaaaact 14341 gatgtgatat aataattcca ttacagaaaa ggagtaaaaa atatgcggca aggtattctt 14401 aaataaaact ataatcaaat agtgggaaca aaggattatg atagtccctt ttgtaggggc 14461 ttagtttttt gtacccaatt taagaatact tttgccttat caattttgac atatccccaa 14521 aaacagcact cacaaacagg tgtatgctgt atatgtgtat gtccgcaaat tatcatcccc 14581 agtggtaaaa gtattttact gctggggatt tttatgccct tcggggcagt aaagggagga 14641 caatcacatg aaaataatca atattggaat tcttgcccat gtagacgctg gaaagacgac 14701 cttgacggag agcctgctat atgccagcgg agccatttca gaaccgggga gcgtcgaaaa 14761 agggacaacg aggacggaca ccccagtttg aggggatact tgttttccta aaactgatgt 14821 gatataataa ttccattaca gaaaaggagt aaaaaatatg cggcaaggta ttcttaaata 14881 aaactataat caaatagtgg gaacaaagga ttatgatagt cccttttgta ggggcttagt 14941 tttttgtacc caatttaaga atacttttgc cttatcaatt ttgacatatc cccaaaaaca 15001 gcactcacaa acaggtgtat gctgtatatg tgtatgtccg caaattatca tccccagtgg 15061 taaaagtatt ttactgctgg ggatttttat gcccttcggg gcagtaaagg gaggacaatc 15121 acatgaaaat aatcaatatt ggaattcttg cccatgtaga cgctggaaag acgaccttga 15181 cggagagcct gctatatgcc agcggagcca tttcagaacc ggggagcgtc gaaaaaggga 15241 caacgaggac ggacaccatg tttttggagc ggcagcgtgg gattaccatt caagcggcag 15301 tcacttcctt ccagtggcac agatgtaaag tcaacattgt ggatacgccc ggccacatgg 15361 attttttggc ggaggtgtac cgctctttgg ctgttttaga tggggccatc ttggtgatct 15421 ccgctaaaga tggcgtgcag gcccagaccc gtattctgtt ccatgccctg cggaaaatga 15481 acattcccac cgttatcttt atcaacaaga tcgaccaggc tggcgttgat ttgcagagcg 15541 tggttcagtc tgttcgggat aagctctccg ccgatattat catcaagcag acggtgtcgc 15601 tgtccccgga aatagtcctg gaggaaaata ccgacataga agcatgggat gcggtcatcg 15661 aaaataacga taaattattg gaaaagtata tcgcaggaga accaatcagc cgggaaaaac 15721 ttgtgcggga ggaacagcgg cgggttcaag acgcctccct gttcccggtc tattatggca 15781 gcgccaaaaa gggccttggc attcaaccgt tgatggatgc ggtgacaggg ctgttccaac 15841 cgattgggga acaggggagc gccgccctat gcggcagcgt tttcaaggtg gagtatacag 15901 attgcggcca gcggcgtgtc tatctacggc tatacagcgg aacgctgcgc ctgcgggata 15961 cggtggccct ggccgggaga gaaaagctga aaatcacaga gatgcgtatt ccatccaaag 16021 gggaaattgt tcggacagac accgcttatc cgggtgaaat tgttatcctt cccagcgaca 16081 gcgtgaggtt aaacgatgta ttaggggacc caacccggct ccctcgtaaa aggtggcgtg 16141 aggaccccct ccccatgctg cggacgtcga ttgcgccgaa aacggcagcg caaagagaac 16201 ggctgctgga cgctcttacg caacttgcgg atactgaccc gcttttgcgc tgcgaggtgg 16261 attccatcac ccatgagatc attctttctt ttttgggccg ggtgcagttg gaggttgttt 16321 ccgctttgct gtcggaaaaa tacaagcttg aaacagtggt aaaggaaccc accgtcattt 16381 atatggagcg gccgctcaaa gcagccagcc acaccatcca tatcgaggtg ccgcccaacc 16441 cgttttgggc atccatcgga ctgtctgtta caccactccc gcttggctcc ggtgtacaat 16501 acgagagccg ggtttcgctg ggatacttga accagagttt tcaaaacgct gtcagggatg 16561 gtatccgtta cgggctggag cagggcttgt tcggctggaa cgtaacggac tgtaagattt 16621 gctttgaata cgggctttat tacagtccgg tcagcacgcc ggcggacttc cgctcattgg 16681 ccccgattgt attggaacag gcattgaagg aatcagggac gcaactgctg gaaccttatc 16741 tctccttcac cctctatgcg ccccgggaat atctttccag ggcttatcat gatgcaccga 16801 aatactgtgc caccatcgaa acggtccagg taaaaaagga tgaagttgtc tttactggcg 16861 agattcccgc ccgctgtata caggcatacc gtactgatct ggccttttac accaacgggc 16921 agagcgtatg ccttacagaa ctgaaagggt atcaggccgc tgtcggcaag ccagtcatcc 16981 agccccgccg tccaaacagc cgcctggaca aggtgcgcta tatgtttcag aagataatgt 17041 aacgtcttgc gcaatgcaag cgttcattgc tggctaggca ggttctagtg atcgttgcaa 17101 catctgatcg accggtagga ggatcggatg ggcaggtggg cgttcgaggg tgtggagtac 17161 gcgacgcatg gcgagatgtg cgcggcgcgg cgacgccggt acgtcgagca tctcgaggtg 17221 ggcatgaact tcacgcaggc cgcgcgggcg gtgggcgtgt ccaaacgcac cggcaaggtg 17281 tggcgcaacg gaaggacacg atcgaacggc aggaacgaga agccatcggt ggactggtat 17341 cgttccaccg tggacattcc ccaaaagatc agttcgaggt atctgagcca ggacgagcgc 17401 atcagcatcg ccgactggcg gaaggccggc atgagcgtgc gcgggatcgc gcgcacgctc 17461 aatcgtcccg cgtcgaccgc cagccgcgag ctggtgcgca acacgaatcc cgcgaccggc 17521 atgtacgagc cgtaccggcc ccagcagatg agcgcggacg gcccagacga cccaagcccg 17581 cgaagatcca tacggtgccc ggcctgctcg catacattcg cgcaggattg cgggcgcatt 17641 ggagtcccga gcagatcgcg gggcgtctgc gcgccgattt cccggataat gatgctatgc 17701 atgtgtgcgc ggagacgatc taccaggcca tctacgtcca ggccaaaggc gaactgaaaa 17761 aggacgtcat caaggccctg aggagcgggc gcgcccaacg ccggccgcac gggcagacgg 17821 actcgcgcaa gccccgtttc cgcgaaccca tgatcatgat cagcgagcgg cccgccgaag 17881 tcgaggaccg ggcgataccc ggtcattggg aaggcgacct gatctgcagc gcggccaaca 17941 aaagcgcgat cggcacgctc gtggaacgct cgacacggtt cacgatcctc ctgcacctgc 18001 ccgacaggca cgacgccaaa cacgtccagc aggccgtcat ccggaaaatg caatacctgc 18061 ccaagctcct gaggaactcg ctgacctggg accagggaag cgagctcacc ctgcacaaac 18121 gcatctcgac cacgttggac atgcaggtgt atttccgcga cccgcattca ccctggcagc 18181 gcggcaccaa cgagaacacc aacgggctcc tgcgccaata cttccccaag ggcaccgacc 18241 tgagcgcata ccccgaggac cacctcgacg cggtcgccga ggaactcaac gaccggcccc 18301 gcaaaacact cggctacagg aaaccatccg agaaaatagg gctatag //